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Tytuł :
Effect of escitalopram dose and treatment duration on CSF Aβ levels in healthy older adults: A controlled clinical trial.
Autorzy :
Sheline YI; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York. .
Snider BJ; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Beer JC; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Seok D; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Fagan AM; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Suckow RF; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Lee JM; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Waligorska T; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Korecka M; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Aselcioglu I; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Morris JC; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Shaw LM; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
Cirrito JR; From the Center for Neuromodulation in Depression and Stress, Department of Psychiatry (Y.I.S., D.S., I.A.), and Departments of Radiology (Y.I.S.), Neurology (Y.I.S.), Biostatistics, Epidemiology and Bioinformatics (J.C.B.), and Pathology (T.W., M.K., L.M.S.), University of Pennsylvania, Philadelphia; Department of Neurology, The Knight Alzheimer Disease Research Center, Hope Center for Neurological Disorders (B.J.S., A.M.F., J.-M.L., J.C.M., J.R.C.), Washington University School of Medicine, St Louis MO; and New York State Psychiatric Institute and Department of Psychiatry (R.F.S.), Columbia University, New York.
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Źródło :
Neurology [Neurology] 2020 Nov 10; Vol. 95 (19), pp. e2658-e2665. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms :
Duration of Therapy*
Amyloid beta-Peptides/*cerebrospinal fluid
Citalopram/*administration & dosage
Peptide Fragments/*cerebrospinal fluid
Serotonin Uptake Inhibitors/*administration & dosage
Aged ; Aged, 80 and over ; Amyloid beta-Peptides/drug effects ; Citalopram/pharmacology ; Cohort Studies ; Dose-Response Relationship, Drug ; Female ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Peptide Fragments/drug effects ; Prospective Studies ; Serotonin Uptake Inhibitors/pharmacology
Czasopismo naukowe
Tytuł :
Divergent Response to the SSRI Citalopram in Male and Female Three-Spine Sticklebacks (Gasterosteus aculeatus).
Autorzy :
Kellner M; School of Natural Sciences, Technology and Environmental Studies, Södertörn University, Alfred Nobels allé 7, 141 89, Huddinge, Sweden.
Olsén KH; School of Natural Sciences, Technology and Environmental Studies, Södertörn University, Alfred Nobels allé 7, 141 89, Huddinge, Sweden. .
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Źródło :
Archives of environmental contamination and toxicology [Arch Environ Contam Toxicol] 2020 Nov; Vol. 79 (4), pp. 478-487. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article
MeSH Terms :
Citalopram/*toxicity
Serotonin Uptake Inhibitors/*toxicity
Smegmamorpha/*physiology
Water Pollutants, Chemical/*toxicity
Aggression/drug effects ; Animals ; Behavior, Animal/drug effects ; Citalopram/pharmacology ; Feeding Behavior ; Female ; Male ; Serotonin Uptake Inhibitors/pharmacology ; Spine
Czasopismo naukowe
Tytuł :
Serotonin transporter gene and escitalopram: depressing medical science.
Autorzy :
Braillon A; University Hospital, 80000, Amiens, France. .
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Źródło :
European journal of clinical pharmacology [Eur J Clin Pharmacol] 2020 Nov; Vol. 76 (11), pp. 1621-1622. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Letter; Comment
MeSH Terms :
Antidepressive Agents, Second-Generation*
Citalopram*
Humans ; Serotonin Plasma Membrane Transport Proteins ; Serotonin Uptake Inhibitors
Opinia redakcyjna
Tytuł :
Combinatorial Pharmacogenomic Algorithm is Predictive of Citalopram and Escitalopram Metabolism in Patients with Major Depressive Disorder.
Autorzy :
Shelton RC; Department of Psychiatry and School of Medicine, The University of Alabama at Birmingham, Birmingham, AL. Electronic address: .
Parikh SV; University of Michigan Comprehensive Depression Center and Department of Psychiatry, and National Network of Depression Centers, Ann Arbor, MI.
Law RA; Myriad Neuroscience, Mason, OH.
Rothschild AJ; University of Massachusetts Medical School and UMass Memorial Healthcare, Worcester, MA.
Thase ME; Perelman School of Medicine of the University of Pennsylvania and the Corporal Michael Crescenz VAMC, Philadelphia, PA.
Dunlop BW; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA.
DeBattista C; Stanford University School of Medicine, Department of Psychiatry and Behavioral Sciences, Stanford, CA.
Conway CR; Department of Psychiatry, Washington University School of Medicine, and the John Cochran Veteran's Administration Hospital, St. Louis, MO.
Forester BP; McLean Hospital, Division of Geriatric Psychiatry, Belmont, MA; Harvard Medical School.
Macaluso M; Department of Psychiatry and Behavioral Sciences, University of Kansas School of Medicine-Wichita, Wichita, KS.
Hain DT; Myriad Neuroscience, Mason, OH.
Aguilar AL; Myriad Neuroscience, Mason, OH.
Brown K; Myriad Genetics, Inc., Salt Lake City, UT.
Lewis DJ; Myriad Neuroscience, Mason, OH.
Jablonski MR; Myriad Neuroscience, Mason, OH.
Greden JF; University of Michigan Comprehensive Depression Center and Department of Psychiatry, and National Network of Depression Centers, Ann Arbor, MI.
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Źródło :
Psychiatry research [Psychiatry Res] 2020 Aug; Vol. 290, pp. 113017. Date of Electronic Publication: 2020 May 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antidepressive Agents/*blood
Antidepressive Agents/*pharmacokinetics
Citalopram/*blood
Citalopram/*pharmacokinetics
Cytochrome P-450 CYP2C19/*genetics
Cytochrome P-450 CYP2D6/*genetics
Cytochrome P-450 CYP3A/*genetics
Depressive Disorder, Major/*drug therapy
Serotonin Uptake Inhibitors/*blood
Serotonin Uptake Inhibitors/*pharmacokinetics
Adult ; Algorithms ; Antidepressive Agents/therapeutic use ; Citalopram/therapeutic use ; Cytochrome P-450 CYP2D6/metabolism ; Cytochrome P-450 CYP3A/metabolism ; Depressive Disorder, Major/blood ; Depressive Disorder, Major/genetics ; Female ; Humans ; Male ; Middle Aged ; Pharmacogenetics ; Pharmacogenomic Testing ; Serotonin Uptake Inhibitors/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Examination of preliminary behavioral and effective connectivity findings from treatment response to citalopram in cocaine use disorder: A dynamic causal modeling study.
Autorzy :
Snyder AD; Institute for Drug and Alcohol Studies; Department of Psychiatry. Electronic address: .
Zuniga E; Institute for Drug and Alcohol Studies.
Ma L; Institute for Drug and Alcohol Studies; Department of Radiology.
Steinberg JL; Institute for Drug and Alcohol Studies; Department of Psychiatry.
Woisard K; Institute for Drug and Alcohol Studies; Virginia Commonwealth University School of Medicine, Richmond, VA, United States.
Narayana PA; Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, Houston, TX, United States.
Lane S; Program in Neuroscience, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, Texas, United States.
Schmitz J; Faillace Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, Texas, United States.
Moeller FG; Institute for Drug and Alcohol Studies; Department of Psychiatry; Department of Pharmacology and Toxicology; Department of Neurology, Virginia Commonwealth University, Richmond, VA, United States. Electronic address: .
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Źródło :
Psychiatry research. Neuroimaging [Psychiatry Res Neuroimaging] 2020 Sep 30; Vol. 303, pp. 111127. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Citalopram/*therapeutic use
Cocaine-Related Disorders/*drug therapy
Corpus Striatum/*drug effects
Magnetic Resonance Imaging/*methods
Prefrontal Cortex/*drug effects
Serotonin Uptake Inhibitors/*therapeutic use
Adult ; Citalopram/pharmacology ; Cocaine-Related Disorders/diagnostic imaging ; Corpus Striatum/diagnostic imaging ; Female ; Humans ; Impulsive Behavior/drug effects ; Impulsive Behavior/physiology ; Male ; Nerve Net/diagnostic imaging ; Nerve Net/drug effects ; Prefrontal Cortex/diagnostic imaging ; Serotonin Uptake Inhibitors/pharmacology ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Coprescribed Benzodiazepines in Older Adults Receiving Antidepressants for Anxiety and Depressive Disorders: Association With Treatment Outcomes.
Autorzy :
Altmann H; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Stahl ST; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara St, Pittsburgh, PA 15213. .; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Gebara MA; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Lenze EJ; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA.
Mulsant BH; Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Blumberger DM; Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Reynolds CF 3rd; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Karp JF; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
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Źródło :
The Journal of clinical psychiatry [J Clin Psychiatry] 2020 Sep 29; Vol. 81 (6). Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Aging*
Outcome Assessment, Health Care*
Antidepressive Agents, Second-Generation/*pharmacology
Anxiety Disorders/*drug therapy
Benzodiazepines/*pharmacology
Citalopram/*pharmacology
Depressive Disorder, Major/*drug therapy
Venlafaxine Hydrochloride/*pharmacology
Aged ; Aged, 80 and over ; Antidepressive Agents, Second-Generation/administration & dosage ; Antidepressive Agents, Second-Generation/adverse effects ; Benzodiazepines/administration & dosage ; Benzodiazepines/adverse effects ; Citalopram/administration & dosage ; Citalopram/adverse effects ; Drug Therapy, Combination ; Female ; Humans ; Male ; Middle Aged ; Venlafaxine Hydrochloride/administration & dosage ; Venlafaxine Hydrochloride/adverse effects
Czasopismo naukowe
Tytuł :
Escitalopram in Adolescents With Generalized Anxiety Disorder: A Double-Blind, Randomized, Placebo-Controlled Study.
Autorzy :
Strawn JR; University of Cincinnati, Department of Psychiatry, Box 670559, Cincinnati, OH 45267-0559. .; Department of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Mills JA; Department of Economics, Lindner College of Business, University of Cincinnati, Cincinnati, Ohio, USA.
Schroeder H; Department of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Mossman SA; Department of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Varney ST; Department of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Ramsey LB; Department of Pediatrics, Divisions of Clinical Pharmacology & Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Poweleit EA; Department of Pediatrics, Divisions of Clinical Pharmacology & Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Desta Z; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana,.
Cecil K; Imaging Research Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
DelBello MP; Department of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
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Źródło :
The Journal of clinical psychiatry [J Clin Psychiatry] 2020 Aug 25; Vol. 81 (5). Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms :
Anti-Anxiety Agents/*therapeutic use
Anxiety Disorders/*drug therapy
Citalopram/*therapeutic use
Serotonin Uptake Inhibitors/*therapeutic use
Adolescent ; Area Under Curve ; Child ; Citalopram/analogs & derivatives ; Citalopram/blood ; Citalopram/pharmacokinetics ; Cytochrome P-450 CYP2C19/genetics ; Cytochrome P-450 CYP2C19/metabolism ; Double-Blind Method ; Female ; Humans ; Male ; Psychiatric Status Rating Scales ; Serotonin Uptake Inhibitors/blood ; Serotonin Uptake Inhibitors/pharmacokinetics ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Spatio-temporal dynamics of EEG features during sleep in major depressive disorder after treatment with escitalopram: a pilot study.
Autorzy :
Wu L; School of automation Hangzhou Dianzi University, HangZhou Economic Development Zone, 1158, 2# Road, BaiYang Street, Hangzhou, 310018, Zhejiang, China.
Wang XQ; Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, 100191, China.
Yang Y; School of automation Hangzhou Dianzi University, HangZhou Economic Development Zone, 1158, 2# Road, BaiYang Street, Hangzhou, 310018, Zhejiang, China.
Dong TF; School of automation Hangzhou Dianzi University, HangZhou Economic Development Zone, 1158, 2# Road, BaiYang Street, Hangzhou, 310018, Zhejiang, China.
Lei L; School of automation Hangzhou Dianzi University, HangZhou Economic Development Zone, 1158, 2# Road, BaiYang Street, Hangzhou, 310018, Zhejiang, China.
Cheng QQ; School of automation Hangzhou Dianzi University, HangZhou Economic Development Zone, 1158, 2# Road, BaiYang Street, Hangzhou, 310018, Zhejiang, China.
Li SX; National Institute on Drug Dependence, Peking University, Beijing, 100191, China. .
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Źródło :
BMC psychiatry [BMC Psychiatry] 2020 Mar 14; Vol. 20 (1), pp. 124. Date of Electronic Publication: 2020 Mar 14.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antidepressive Agents, Second-Generation*/pharmacology
Antidepressive Agents, Second-Generation*/therapeutic use
Citalopram*/pharmacology
Citalopram*/therapeutic use
Depressive Disorder, Major*/drug therapy
Depressive Disorder, Major*/physiopathology
Electroencephalography*
Adult ; Humans ; Male ; Pilot Projects ; Sleep ; Young Adult
Czasopismo naukowe
Tytuł :
The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter.
Autorzy :
Plenge P; Laboratory for Membrane Protein Dynamics. Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Abramyan AM; Computational Chemistry and Molecular Biophysics Unit, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.
Sørensen G; Lundbeck Research, H. Lundbeck A/S, Copenhagen, Denmark.
Mørk A; Lundbeck Research, H. Lundbeck A/S, Copenhagen, Denmark.
Weikop P; Laboratory of Neuropsychiatry, Psychiatric Centre Copenhagen, University of Copenhagen, Copenhagen, Denmark.
Gether U; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Bang-Andersen B; Lundbeck Research, H. Lundbeck A/S, Copenhagen, Denmark. .; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. .
Shi L; Computational Chemistry and Molecular Biophysics Unit, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health, Baltimore, MD, USA. .
Loland CJ; Laboratory for Membrane Protein Dynamics. Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. .
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Źródło :
Nature communications [Nat Commun] 2020 Mar 20; Vol. 11 (1), pp. 1491. Date of Electronic Publication: 2020 Mar 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Allosteric Site/*drug effects
Citalopram/*pharmacology
Imipramine/*pharmacology
Serotonin Plasma Membrane Transport Proteins/*chemistry
Serotonin Plasma Membrane Transport Proteins/*metabolism
Serotonin Uptake Inhibitors/*pharmacology
Allosteric Regulation/drug effects ; Allosteric Site/genetics ; Animals ; Antidepressive Agents/pharmacology ; Citalopram/chemistry ; Drug Development ; Genetic Engineering ; Imipramine/chemistry ; Ligands ; Molecular Docking Simulation ; Mutagenesis, Site-Directed ; Protein Conformation ; Rats ; Serotonin/metabolism ; Serotonin Plasma Membrane Transport Proteins/genetics
Czasopismo naukowe
Tytuł :
Dual Roles for the TSPYL Family in Mediating Serotonin Transport and the Metabolism of Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder.
Autorzy :
Qin S; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.
Eugene AR; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.
Liu D; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.
Zhang L; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.
Neavin D; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.
Biernacka JM; Department of Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Yu J; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.
Weinshilboum RM; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.
Wang L; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2020 Mar; Vol. 107 (3), pp. 662-670. Date of Electronic Publication: 2019 Nov 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Citalopram/*administration & dosage
Cytochrome P-450 CYP2C19/*genetics
Depressive Disorder, Major/*drug therapy
Nuclear Proteins/*genetics
Serotonin Uptake Inhibitors/*administration & dosage
Caco-2 Cells ; Citalopram/pharmacokinetics ; Depressive Disorder, Major/genetics ; Depressive Disorder, Major/physiopathology ; Hep G2 Cells ; Humans ; Linkage Disequilibrium ; Pharmacogenetics ; Polymorphism, Single Nucleotide ; Serotonin/metabolism ; Serotonin Plasma Membrane Transport Proteins/genetics ; Serotonin Uptake Inhibitors/pharmacokinetics ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Editorial: Antidepressants to the Rescue in Severe Mood Dysregulation and Disruptive Mood Dysregulation Disorder?
Autorzy :
Carlson GA; Renaissance School of Medicine at Stony Brook University, NY. Electronic address: .
Klein DN; State University of New York at Stony Brook, NY.
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Źródło :
Journal of the American Academy of Child and Adolescent Psychiatry [J Am Acad Child Adolesc Psychiatry] 2020 Mar; Vol. 59 (3), pp. 339-341. Date of Electronic Publication: 2019 May 22.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
Citalopram*/therapeutic use
Irritable Mood*
Adolescent ; Adult ; Antidepressive Agents ; Attention Deficit and Disruptive Behavior Disorders/drug therapy ; Child ; Double-Blind Method ; Humans ; Infant ; Mood Disorders/drug therapy
Raport
Tytuł :
A Randomized Double-Blind Placebo-Controlled Trial of Combined Escitalopram and Memantine for Older Adults With Major Depression and Subjective Memory Complaints.
Autorzy :
Lavretsky H; Jane and Terry Semel Institute for Neuroscience and Human Behavior, UCLA (HL, KTL, BK-S, BFH, JY, AG, PW, KT-U, LME, PS), Los Angeles, CA. Electronic address: .
Laird KT; Jane and Terry Semel Institute for Neuroscience and Human Behavior, UCLA (HL, KTL, BK-S, BFH, JY, AG, PW, KT-U, LME, PS), Los Angeles, CA.
Krause-Sorio B; Jane and Terry Semel Institute for Neuroscience and Human Behavior, UCLA (HL, KTL, BK-S, BFH, JY, AG, PW, KT-U, LME, PS), Los Angeles, CA.
Heimberg BF; Jane and Terry Semel Institute for Neuroscience and Human Behavior, UCLA (HL, KTL, BK-S, BFH, JY, AG, PW, KT-U, LME, PS), Los Angeles, CA.
Yeargin J; Jane and Terry Semel Institute for Neuroscience and Human Behavior, UCLA (HL, KTL, BK-S, BFH, JY, AG, PW, KT-U, LME, PS), Los Angeles, CA.
Grzenda A; Jane and Terry Semel Institute for Neuroscience and Human Behavior, UCLA (HL, KTL, BK-S, BFH, JY, AG, PW, KT-U, LME, PS), Los Angeles, CA.
Wu P; Jane and Terry Semel Institute for Neuroscience and Human Behavior, UCLA (HL, KTL, BK-S, BFH, JY, AG, PW, KT-U, LME, PS), Los Angeles, CA.
Thana-Udom K; Jane and Terry Semel Institute for Neuroscience and Human Behavior, UCLA (HL, KTL, BK-S, BFH, JY, AG, PW, KT-U, LME, PS), Los Angeles, CA; Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University (KT-U), Bangkok, Thailand.
Ercoli LM; Jane and Terry Semel Institute for Neuroscience and Human Behavior, UCLA (HL, KTL, BK-S, BFH, JY, AG, PW, KT-U, LME, PS), Los Angeles, CA.
Siddarth P; Jane and Terry Semel Institute for Neuroscience and Human Behavior, UCLA (HL, KTL, BK-S, BFH, JY, AG, PW, KT-U, LME, PS), Los Angeles, CA.
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Źródło :
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry [Am J Geriatr Psychiatry] 2020 Feb; Vol. 28 (2), pp. 178-190. Date of Electronic Publication: 2019 Aug 22.
Typ publikacji :
Clinical Trial, Phase IV; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms :
Citalopram/*administration & dosage
Depressive Disorder, Major/*drug therapy
Memantine/*administration & dosage
Memory/*drug effects
Serotonin Uptake Inhibitors/*administration & dosage
Aged ; Citalopram/adverse effects ; Double-Blind Method ; Drug Therapy, Combination ; Female ; Humans ; Male ; Memantine/adverse effects ; Psychiatric Status Rating Scales ; Serotonin Uptake Inhibitors/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Do environmentally relevant concentrations of fluoxetine and citalopram impair stress-related behavior in zebrafish (Danio rerio) embryos?
Autorzy :
Zindler F; Aquatic Ecology and Toxicology Section, Centre for Organismal Studies, University of Heidelberg, Im Neuenheimer Feld 504, Heidelberg, D-69120, Germany. Electronic address: .
Stoll S; Aquatic Ecology and Toxicology Section, Centre for Organismal Studies, University of Heidelberg, Im Neuenheimer Feld 504, Heidelberg, D-69120, Germany.
Baumann L; Aquatic Ecology and Toxicology Section, Centre for Organismal Studies, University of Heidelberg, Im Neuenheimer Feld 504, Heidelberg, D-69120, Germany.
Knoll S; Institute for Physical and Theoretical Chemistry, University of Tübingen, Auf der Morgenstelle 18, Tübingen, D-72076, Germany.
Huhn C; Institute for Physical and Theoretical Chemistry, University of Tübingen, Auf der Morgenstelle 18, Tübingen, D-72076, Germany.
Braunbeck T; Aquatic Ecology and Toxicology Section, Centre for Organismal Studies, University of Heidelberg, Im Neuenheimer Feld 504, Heidelberg, D-69120, Germany.
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Źródło :
Chemosphere [Chemosphere] 2020 Dec; Vol. 261, pp. 127753. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article
MeSH Terms :
Behavior, Animal/*drug effects
Embryo, Nonmammalian/*drug effects
Oxidative Stress/*drug effects
Serotonin Uptake Inhibitors/*toxicity
Water Pollutants, Chemical/*toxicity
Zebrafish/*physiology
Animals ; Bioaccumulation/drug effects ; Citalopram/metabolism ; Citalopram/toxicity ; Embryo, Nonmammalian/metabolism ; Embryo, Nonmammalian/physiology ; Environmental Exposure ; Fluoxetine/metabolism ; Fluoxetine/toxicity ; Serotonin Uptake Inhibitors/metabolism ; Swimming ; Water Pollutants, Chemical/metabolism
Czasopismo naukowe
Tytuł :
Development and pharmaceutical evaluation of oral fast dissolving thin film of escitalopram: A patient friendly dosage form.
Autorzy :
Mushtaque M; Department of Pharmaceutics, Faculty of Pharmacy & Pharmaceutical Science, University of Karachi, Karachi, Pakistan.
Muhammad IN; Department of Pharmaceutics, Faculty of Pharmacy & Pharmaceutical Science, University of Karachi, Karachi, Pakistan.
Fareed Hassan SM; Department of Pharmaceutics, Faculty of Pharmacy & Pharmaceutical Science, University of Karachi, Karachi, Pakistan.
Ali A; Department of Pharmaceutics, Faculty of Pharmacy & Pharmaceutical Science, University of Karachi, Karachi, Pakistan/ Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, Karachi, Pakistan.
Masood R; Department of Pharmaceutics, Faculty of Pharmacy & Pharmaceutical Science, University of Karachi, Karachi, Pakistan.
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Źródło :
Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2020 Jan; Vol. 33 (1), pp. 183-189.
Typ publikacji :
Journal Article
MeSH Terms :
Citalopram/*chemistry
Citalopram/*pharmacology
Drug Compounding/*methods
Administration, Oral ; Citalopram/administration & dosage ; Drug Delivery Systems/methods ; Drug Liberation ; Drug Stability ; Humans ; Hypromellose Derivatives/chemistry ; Physical Phenomena ; Polyethylene Glycols/chemistry ; Sensation/drug effects ; Solubility ; Spectrophotometry/methods ; Surface Properties
Czasopismo naukowe
Tytuł :
Natural and semisynthetic polymers blended orodispersible films of citalopram.
Autorzy :
Shahzad Y; Department of Pharmacy, COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan.
Maqbool M; Faculty of Pharmacy, University of Central Punjab, Lahore, Pakistan.
Hussain T; Department of Pharmacy, COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan.
Yousaf AM; Department of Pharmacy, COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan.
Khan IU; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
Mahmood T; Faculty of Pharmacy, University of Central Punjab, Lahore, Pakistan.
Jamshaid M; Faculty of Pharmacy, University of Central Punjab, Lahore, Pakistan.
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Źródło :
Natural product research [Nat Prod Res] 2020 Jan; Vol. 34 (1), pp. 16-25. Date of Electronic Publication: 2019 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Citalopram/*chemical synthesis
Polymers/*chemistry
Abelmoschus/chemistry ; Administration, Oral ; Citalopram/administration & dosage ; Humans ; Hypromellose Derivatives/chemistry ; Serotonin Uptake Inhibitors/administration & dosage ; Serotonin Uptake Inhibitors/chemical synthesis ; Solubility ; Tensile Strength ; X-Ray Diffraction
Czasopismo naukowe
Tytuł :
Probable Galactorrhea Associated with Sequential Trials of Escitalopram and Duloxetine in an Adolescent Female.
Autorzy :
McGrane IR; College of Health Professions and Biomedical Sciences, Skaggs School of Pharmacy, The University of Montana, Missoula, Montana.
Morefield CM; College of Health Professions and Biomedical Sciences, Skaggs School of Pharmacy, The University of Montana, Missoula, Montana.
Aytes KL; Department of Psychiatry, Providence St. Patrick Hospital, Missoula, Montana.
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Źródło :
Journal of child and adolescent psychopharmacology [J Child Adolesc Psychopharmacol] 2019 Dec; Vol. 29 (10), pp. 788-789. Date of Electronic Publication: 2019 Jul 24.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Antidepressive Agents*/adverse effects
Antidepressive Agents*/therapeutic use
Citalopram*/adverse effects
Citalopram*/therapeutic use
Duloxetine Hydrochloride*/adverse effects
Duloxetine Hydrochloride*/therapeutic use
Galactorrhea*/diagnosis
Galactorrhea*/drug therapy
Serotonin Uptake Inhibitors*/adverse effects
Serotonin Uptake Inhibitors*/therapeutic use
Adolescent ; Female ; Humans ; Suicide, Attempted
Raport
Tytuł :
Effects of selective serotonin reuptake inhibitors on DNA damage in patients with depression.
Autorzy :
Ahmadimanesh M; Department of Pharmacodynamics and Toxicology, Mashhad University of Medical Sciences, Mashhad, Iran.
Abbaszadegan MR; Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Morshedi Rad D; Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Moallem SA; Department of Pharmacodynamics and Toxicology, Mashhad University of Medical Sciences, Mashhad, Iran.; Department of Pharmacology and Toxicology, Al Zahra University, Karbala, Iraq.
Mohammadpour AH; Department of Clinical Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.; Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Ghahremani MH; Department of Toxicology-Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Farid Hosseini F; Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Behdani F; Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Akhondpour Manteghi A; Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Jowsey P; National Institute for Health Research (NIHR), Health Protection Research Unit for Chemical and Radiation Threats and Hazards, Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, UK.
Shabani Behbahani F; Department of Pharmacodynamics and Toxicology, Mashhad University of Medical Sciences, Mashhad, Iran.
Moallem SMH; School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Etemad L; Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
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Źródło :
Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2019 Nov; Vol. 33 (11), pp. 1364-1376. Date of Electronic Publication: 2019 Sep 26.
Typ publikacji :
Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Citalopram/*administration & dosage
DNA Damage/*drug effects
Depressive Disorder/*drug therapy
Serotonin Uptake Inhibitors/*administration & dosage
Sertraline/*administration & dosage
Adult ; Case-Control Studies ; Citalopram/pharmacology ; Comet Assay ; DNA Glycosylases/genetics ; Depressive Disorder/genetics ; Female ; Humans ; Male ; Middle Aged ; Oxidative Stress/drug effects ; Poly (ADP-Ribose) Polymerase-1/genetics ; Serotonin Uptake Inhibitors/pharmacology ; Sertraline/pharmacology
Czasopismo naukowe
Tytuł :
Application of LC-ESI-MS/MS Method for Analysis of Escitalopram Oxalate in Human Urine and Pharmaceutical Dosage Forms.
Autorzy :
Badulla WFS; Department of Analytical Chemistry, Faculty of Pharmacy, Aden University, Al-Jumhuriah St., Khormakser District, Aden, Yemen.
Atkoşar Z; Department of Analytical Chemistry, Faculty of Pharmacy, Yeşiltepe, Anadolu Üniversitesi Yunusemre Kampüsü, 26470, Tepebaşı/Eskişehir, Türkiye.
Arli G; Department of Analytical Chemistry, Faculty of Pharmacy, Yeşiltepe, Anadolu Üniversitesi Yunusemre Kampüsü, 26470, Tepebaşı/Eskişehir, Türkiye.
Şener E; Department of Analytical Chemistry, Faculty of Pharmacy, Yeşiltepe, Anadolu Üniversitesi Yunusemre Kampüsü, 26470, Tepebaşı/Eskişehir, Türkiye.
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Źródło :
Journal of chromatographic science [J Chromatogr Sci] 2020 Jan 23; Vol. 58 (2), pp. 91-97.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Antidepressive Agents/*urine
Chromatography, High Pressure Liquid/*methods
Citalopram/*urine
Tandem Mass Spectrometry/*methods
Antidepressive Agents/isolation & purification ; Citalopram/isolation & purification ; Dosage Forms ; Humans ; Liquid-Liquid Extraction ; Spectrometry, Mass, Electrospray Ionization/methods
Czasopismo naukowe
Tytuł :
Supramaximal Dose of Ecitalopram-Associated Hematuria in an Adolescent With Obsessive-Compulsive Disorder: A Case Report.
Autorzy :
Naguy A; Al-Manara CAP Centre, Kuwait Centre for Mental Health (KCMH), Shuwaikh, State of Kuwait , Cairo, Egypt. Rhode Island Hospital Brown University Providence, RI Al-Manara CAP Centre, KCMH, Shuwaikh, State of Kuwait. Tufts University, Medford, MA.
Abdelhamid HS
Elsori D
Alamiri B
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Źródło :
Journal of clinical psychopharmacology [J Clin Psychopharmacol] 2020 Jan/Feb; Vol. 40 (1), pp. 102-103.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Citalopram/*adverse effects
Hematuria/*chemically induced
Obsessive-Compulsive Disorder/*drug therapy
Serotonin Uptake Inhibitors/*adverse effects
Adolescent ; Citalopram/administration & dosage ; Humans ; Male ; Serotonin Uptake Inhibitors/administration & dosage
Raport
Tytuł :
An investigation of cortical thickness and antidepressant response in major depressive disorder: A CAN-BIND study report.
Autorzy :
Suh JS; Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada; Mood Disorders Program and Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
Minuzzi L; Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada; Mood Disorders Program and Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Raamana PR; Rotman Research Institute, Baycrest Health Sciences; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Davis A; Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada.
Hall GB; Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada.
Harris J; Department of Computing Science, University of Alberta, Edmonton, AB, Canada.
Hassel S; Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Mathison Centre for Mental Health Research and Education, University of Calgary, Calgary, AB, Canada.
Zamyadi M; Rotman Research Institute, Baycrest Health Sciences; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Arnott SR; Rotman Research Institute, Baycrest Health Sciences; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Alders GL; Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada; Mood Disorders Program and Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
Sassi RB; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Milev R; Departments of Psychiatry and Psychology, Queen's University and Providence Care Hospital, Kingston, ON, Canada.
Lam RW; Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
MacQueen GM; Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Mathison Centre for Mental Health Research and Education, University of Calgary, Calgary, AB, Canada.
Strother SC; Rotman Research Institute, Baycrest Health Sciences; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Kennedy SH; Canadian Biomarker Integration Network for Depression, St. Michael's Hospital, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Frey BN; Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada; Mood Disorders Program and Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada. Electronic address: .
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Źródło :
NeuroImage. Clinical [Neuroimage Clin] 2020; Vol. 25, pp. 102178. Date of Electronic Publication: 2020 Jan 13.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antidepressive Agents/*pharmacology
Aripiprazole/*pharmacology
Cerebral Cortex/*drug effects
Cerebral Cortex/*pathology
Citalopram/*pharmacology
Depressive Disorder, Major/*drug therapy
Depressive Disorder, Major/*pathology
Neuroimaging/*methods
Adult ; Antidepressive Agents/administration & dosage ; Aripiprazole/administration & dosage ; Cerebral Cortex/diagnostic imaging ; Citalopram/administration & dosage ; Depressive Disorder, Major/diagnostic imaging ; Drug Therapy, Combination ; Female ; Humans ; Longitudinal Studies ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Outcome Assessment, Health Care
Czasopismo naukowe

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