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Tytuł :
Inhibitory Effects of P2Y12 Receptor Antagonist on PAR1- and PAR4-AP-Induced Platelet Aggregation in Patients with Stroke or TIA.
Autorzy :
Kamada A; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan.
Shimizu M; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan. Electronic address: .
Oura K; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan.
Yoshida M; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan.
Tsuda K; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan.
Oi K; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan.
Ishigaku Y; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan. Electronic address: .
Natori T; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan.
Narumi S; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan.
Itabashi R; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan. Electronic address: .
Maeda T; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan. Electronic address: .
Terayama Y; Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate 028-3695, Japan; Department of Neurology, Shonan Keiiku Hospital, Japan.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2021 Mar; Vol. 30 (3), pp. 105547. Date of Electronic Publication: 2020 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Platelet Function Tests*
Blood Platelets/*drug effects
Clopidogrel/*therapeutic use
Ischemic Attack, Transient/*drug therapy
Ischemic Stroke/*drug therapy
Oligopeptides/*pharmacology
Platelet Aggregation/*drug effects
Platelet Aggregation Inhibitors/*therapeutic use
Purinergic P2Y Receptor Antagonists/*therapeutic use
Adenosine Diphosphate/pharmacology ; Adenosine Monophosphate/analogs & derivatives ; Adenosine Monophosphate/pharmacology ; Adult ; Aged ; Aged, 80 and over ; Blood Platelets/metabolism ; Case-Control Studies ; Clopidogrel/adverse effects ; Female ; Humans ; Ischemic Attack, Transient/blood ; Ischemic Attack, Transient/diagnosis ; Ischemic Stroke/blood ; Ischemic Stroke/diagnosis ; Male ; Middle Aged ; Platelet Aggregation Inhibitors/adverse effects ; Predictive Value of Tests ; Prospective Studies ; Purinergic P2Y Receptor Antagonists/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
CYP2C19 Loss-of-Function is Associated with Increased Risk of Ischemic Stroke after Transient Ischemic Attack in Intracranial Atherosclerotic Disease.
Autorzy :
Patel PD; Vanderbilt University School of Medicine, 1161 21st Ave S # D3300, Nashville, TN 37232, United States; Surgical Outcomes Center for Kids, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, United States. Electronic address: .
Vimalathas P; Vanderbilt University School of Medicine, 1161 21st Ave S # D3300, Nashville, TN 37232, United States.
Niu X; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
Shannon CN; Surgical Outcomes Center for Kids, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, United States; Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, TN, United States.
Denny JC; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
Peterson JF; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
Chitale RV; Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, TN, United States.
Fusco MR; Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, TN, United States.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2021 Feb; Vol. 30 (2), pp. 105464. Date of Electronic Publication: 2020 Nov 24.
Typ publikacji :
Journal Article
MeSH Terms :
Pharmacogenomic Variants*
Clopidogrel/*adverse effects
Cytochrome P-450 CYP2C19/*genetics
Drug Resistance/*genetics
Intracranial Arteriosclerosis/*drug therapy
Ischemic Attack, Transient/*prevention & control
Ischemic Stroke/*prevention & control
Platelet Aggregation Inhibitors/*adverse effects
Aged ; Clopidogrel/administration & dosage ; Databases, Factual ; Female ; Humans ; Intracranial Arteriosclerosis/complications ; Intracranial Arteriosclerosis/diagnostic imaging ; Ischemic Attack, Transient/diagnostic imaging ; Ischemic Attack, Transient/etiology ; Ischemic Stroke/diagnostic imaging ; Ischemic Stroke/etiology ; Male ; Middle Aged ; Platelet Aggregation Inhibitors/administration & dosage ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Ethnic variance on long term clinical outcomes of concomitant use of proton pump inhibitors and clopidogrel in patients with stent implantation: A PRISMA-complaint systematic review with meta-analysis.
Autorzy :
Shi W; State Key Laboratory of Cardiovascular Disease.; Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yan L; State Key Laboratory of Cardiovascular Disease.; Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yang J; State Key Laboratory of Cardiovascular Disease.; Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yu M; State Key Laboratory of Cardiovascular Disease.; Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Feb 12; Vol. 100 (6), pp. e24366.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Blood Vessel Prosthesis*
Blood Vessel Prosthesis Implantation*/adverse effects
Blood Vessel Prosthesis Implantation*/methods
Continental Population Groups*/statistics & numerical data
Percutaneous Coronary Intervention*/adverse effects
Percutaneous Coronary Intervention*/methods
Stents*
Clopidogrel/*therapeutic use
Platelet Aggregation Inhibitors/*therapeutic use
Proton Pump Inhibitors/*therapeutic use
Clopidogrel/administration & dosage ; Coronary Occlusion/prevention & control ; Coronary Occlusion/therapy ; Drug Therapy, Combination ; Humans ; Platelet Aggregation Inhibitors/administration & dosage ; Proton Pump Inhibitors/administration & dosage ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Correlation study of CYP2C19 gene polymorphism and clopidogrel resistance in Han Chinese patients with cerebral infarction in Guizhou region.
Autorzy :
Shi GX; Department of Neurology, Guizhou Aerospace Hospital, Zunyi.
Zhao ZH; Department of Dermatology, Beijing Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing, China.
Yang XY; Department of Neurology, Guizhou Aerospace Hospital, Zunyi.
Lin M; Department of Neurology, Guizhou Aerospace Hospital, Zunyi.
Chen ZX; Department of Neurology, Guizhou Aerospace Hospital, Zunyi.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Feb 12; Vol. 100 (6), pp. e24481.
Typ publikacji :
Journal Article
MeSH Terms :
Cerebral Infarction/*drug therapy
Clopidogrel/*therapeutic use
Cytochrome P-450 CYP2C19/*genetics
Polymorphism, Genetic/*genetics
Asian Continental Ancestry Group/genetics ; China ; Clopidogrel/pharmacokinetics ; Drug Resistance/genetics ; Female ; Gene Frequency/genetics ; Genotyping Techniques ; Humans ; Male ; Middle Aged ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Effects of the ABCB1 C3435T single nucleotide polymorphism on major adverse cardiovascular events in acute coronary syndrome or coronary artery disease patients undergoing percutaneous coronary intervention and treated with clopidogrel: A systematic review and meta-analysis.
Autorzy :
Biswas M; Department of Pharmacy, University of Rajshahi , Rajshahi, Bangladesh.
Rahaman S; Department of Pharmacy, University of Rajshahi , Rajshahi, Bangladesh.
Biswas TK; Department of Medicine, Faridpur Medical College Hospital , Faridpur, Bangladesh.
Ibrahim B; School of Pharmaceutical Sciences, Universiti Sains Malaysia , Penang, Malaysia.
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Źródło :
Expert opinion on drug safety [Expert Opin Drug Saf] 2020 Dec; Vol. 19 (12), pp. 1605-1616. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Clopidogrel/*administration & dosage
Percutaneous Coronary Intervention/*methods
ATP Binding Cassette Transporter, Subfamily B/genetics ; Acute Coronary Syndrome/therapy ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/genetics ; Clopidogrel/adverse effects ; Coronary Artery Disease/therapy ; Genotype ; Hemorrhage/chemically induced ; Humans ; Platelet Aggregation Inhibitors/administration & dosage ; Platelet Aggregation Inhibitors/adverse effects ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
Clopidogrel drug interactions: a review of the evidence and clinical implications.
Autorzy :
Lee CH; Division of Cardiology, University of Florida College of Medicine-Jacksonville , Jacksonville, FL, USA.; Division of Cardiology, Department of Internal Medicine, Veterans Health Service Medical Center , Seoul, Korea.
Franchi F; Division of Cardiology, University of Florida College of Medicine-Jacksonville , Jacksonville, FL, USA.
Angiolillo DJ; Division of Cardiology, University of Florida College of Medicine-Jacksonville , Jacksonville, FL, USA.
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Źródło :
Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2020 Nov; Vol. 16 (11), pp. 1079-1096. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Clopidogrel/*adverse effects
Platelet Aggregation Inhibitors/*adverse effects
Purinergic P2Y Receptor Antagonists/*adverse effects
Animals ; Cardiovascular Diseases/drug therapy ; Clopidogrel/administration & dosage ; Drug Interactions ; Humans ; Platelet Aggregation Inhibitors/administration & dosage ; Polypharmacy ; Purinergic P2Y Receptor Antagonists/administration & dosage
Czasopismo naukowe
Tytuł :
CYP2C19 status and risk of major adverse cardiovascular events in peripheral artery disease: Insights from the EUCLID Trial.
Autorzy :
Gutierrez JA; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Division of Cardiology, Duke University School of Medicine, Durham, NC. Electronic address: .
Heizer GM; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Jones WS; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Division of Cardiology, Duke University School of Medicine, Durham, NC.
Rockhold FW; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Mahaffey KW; Stanford Center for Clinical Research, Stanford University School of Medicine, Stanford, CA.
Fowkes FGR; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
Berger JS; Departments of Medicine and Surgery, New York University School of Medicine, New York, NY.
Baumgartner I; Swiss Cardiovascular Centre, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Held P; University of Gothenburg, Sweden.
Katona BG; AstraZeneca Gaithersburg, Gaithersburg, MD.
Norgren L; Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Blomster JI; Turku University Hospital, Turku, Finland.
Hiatt WR; University of Colorado School of Medicine and CPC Clinical Research, Aurora, CO.
Patel MR; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Division of Cardiology, Duke University School of Medicine, Durham, NC.
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Źródło :
American heart journal [Am Heart J] 2020 Nov; Vol. 229, pp. 118-120. Date of Electronic Publication: 2020 Aug 16.
Typ publikacji :
Letter; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Cardiovascular Diseases*/diagnosis
Cardiovascular Diseases*/etiology
Cardiovascular Diseases*/mortality
Cardiovascular Diseases*/surgery
Clopidogrel*/administration & dosage
Clopidogrel*/adverse effects
Clopidogrel*/pharmacokinetics
Hemorrhage*/chemically induced
Hemorrhage*/diagnosis
Ischemia*/etiology
Ischemia*/surgery
Peripheral Arterial Disease*/complications
Peripheral Arterial Disease*/drug therapy
Peripheral Arterial Disease*/genetics
Vascular Surgical Procedures*/methods
Vascular Surgical Procedures*/statistics & numerical data
Cytochrome P-450 CYP2C19/*genetics
Extremities/blood supply ; Female ; Humans ; Loss of Function Mutation ; Male ; Middle Aged ; Outcome and Process Assessment, Health Care ; Pharmacogenomic Testing/methods ; Platelet Aggregation Inhibitors/administration & dosage ; Platelet Aggregation Inhibitors/adverse effects ; Platelet Aggregation Inhibitors/pharmacokinetics
Raport
Tytuł :
Perioperative changes of response to antiplatelet medication in vascular surgery patients.
Autorzy :
Hummel T; Department of Vascular Surgery, St. Josef Hospital, Katholisches Klinikum Bochum, Ruhr University Bochum, Bochum, Germany.
Meves SH; Department of Neurology, St. Josef Hospital, Katholisches Klinikum Bochum, Ruhr University Bochum, Bochum, Germany.
Breuer-Kaiser A; Department of Anaesthesiology, St. Josef Hospital, Katholisches Klinikum Bochum, Ruhr University Bochum, Bochum, Germany.
Düsterwald JO; Department of Vascular Surgery, St. Josef Hospital, Katholisches Klinikum Bochum, Ruhr University Bochum, Bochum, Germany.
Mühlberger D; Department of Vascular Surgery, St. Josef Hospital, Katholisches Klinikum Bochum, Ruhr University Bochum, Bochum, Germany.
Mumme A; Department of Vascular Surgery, St. Josef Hospital, Katholisches Klinikum Bochum, Ruhr University Bochum, Bochum, Germany.
Neubauer H; Department of Cardiology, St. Josef Hospital, Katholisches Klinikum Bochum, Ruhr University Bochum, Bochum, Germany.
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Źródło :
PloS one [PLoS One] 2020 Dec 29; Vol. 15 (12), pp. e0244330. Date of Electronic Publication: 2020 Dec 29 (Print Publication: 2020).
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Aspirin/*administration & dosage
Carotid Stenosis/*surgery
Clopidogrel/*administration & dosage
Peripheral Arterial Disease/*surgery
Platelet Aggregation Inhibitors/*administration & dosage
Vascular Surgical Procedures/*adverse effects
Aged ; Aged, 80 and over ; Aspirin/therapeutic use ; Clopidogrel/therapeutic use ; Empirical Research ; Female ; Humans ; Male ; Perioperative Care/instrumentation ; Platelet Aggregation Inhibitors/therapeutic use ; Platelet Count ; Prevalence ; Prospective Studies ; Risk Assessment ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Dual Antiplatelet Therapy Beyond 90 days in Symptomatic Intracranial Stenosis in the SAMMPRIS Trial.
Autorzy :
Abdul Rahman L; Department of Neurology, 96 Jonathan Lucas Street, Clinical Science Building 301, MSC 606, Medical University of South Carolina, Charleston 29425-8050, SC, United States. Electronic address: .
Turan TN; Department of Neurology, 96 Jonathan Lucas Street, Clinical Science Building 301, MSC 606, Medical University of South Carolina, Charleston 29425-8050, SC, United States. Electronic address: .
Cotsonis G; Department of Biostatistics and Bioinformatics, 1518 Clifton Rd, Emory University Rollins School of Public Health, Atlanta 30322, GA, United States. Electronic address: .
Almallouhi E; Department of Neurology, 96 Jonathan Lucas Street, Clinical Science Building 301, MSC 606, Medical University of South Carolina, Charleston 29425-8050, SC, United States. Electronic address: .
Holmstedt CA; Department of Neurology, 96 Jonathan Lucas Street, Clinical Science Building 301, MSC 606, Medical University of South Carolina, Charleston 29425-8050, SC, United States. Electronic address: .
Chimowitz MI; Department of Neurology, 96 Jonathan Lucas Street, Clinical Science Building 301, MSC 606, Medical University of South Carolina, Charleston 29425-8050, SC, United States. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Dec; Vol. 29 (12), pp. 105254. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Dual Anti-Platelet Therapy*/adverse effects
Aspirin/*administration & dosage
Clopidogrel/*administration & dosage
Intracranial Arteriosclerosis/*drug therapy
Platelet Aggregation Inhibitors/*administration & dosage
Aged ; Angioplasty/instrumentation ; Aspirin/adverse effects ; Clopidogrel/adverse effects ; Drug Administration Schedule ; Female ; Hemorrhage/chemically induced ; Humans ; Intracranial Arteriosclerosis/complications ; Intracranial Arteriosclerosis/diagnostic imaging ; Male ; Middle Aged ; Platelet Aggregation Inhibitors/adverse effects ; Risk Factors ; Stents ; Stroke/etiology ; Stroke/prevention & control ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Ipsilateral Nonstenotic Carotid Disease in Minor Ischemic Stroke: an Exploratory Analysis of The POINT Randomized Clinical Trial.
Autorzy :
Bulwa Z; Department of Neurology, University of Chicago Medical Center, 5841 South Maryland Avenue MC 2030, Chicago, IL 60637, USA. Electronic address: .
Saleh Velez FG; Department of Neurology, University of Chicago Medical Center, 5841 South Maryland Avenue MC 2030, Chicago, IL 60637, USA. Electronic address: .
Brorson JR; Department of Neurology, University of Chicago Medical Center, 5841 South Maryland Avenue MC 2030, Chicago, IL 60637, USA. Electronic address: .
Pinto CB; University of Sao Paulo, Institute of Psychology, Sao Paulo, Brazil. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Nov; Vol. 29 (11), pp. 105115. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Secondary Prevention*
Aspirin/*therapeutic use
Carotid Artery Diseases/*drug therapy
Clopidogrel/*therapeutic use
Ischemic Attack, Transient/*prevention & control
Platelet Aggregation Inhibitors/*therapeutic use
Stroke/*drug therapy
Aged ; Aspirin/adverse effects ; Carotid Artery Diseases/diagnostic imaging ; Carotid Artery Diseases/mortality ; Clopidogrel/adverse effects ; Comorbidity ; Double-Blind Method ; Dual Anti-Platelet Therapy ; Female ; Humans ; Ischemic Attack, Transient/diagnosis ; Ischemic Attack, Transient/mortality ; Male ; Middle Aged ; Platelet Aggregation Inhibitors/adverse effects ; Recurrence ; Risk Factors ; Stroke/diagnosis ; Stroke/etiology ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Resistance to Antiplatelet Therapy Is Associated With Symptoms of Cerebral Ischemia in Carotid Artery Disease.
Autorzy :
Ball STE; Academic Surgery Unit, Institute of Cardiovascular Sciences, 5292University of Manchester, Manchester, United Kingdom.
Taylor R; Academic Surgery Unit, Institute of Cardiovascular Sciences, 5292University of Manchester, Manchester, United Kingdom.
McCollum CN; Academic Surgery Unit, Institute of Cardiovascular Sciences, 5292University of Manchester, Manchester, United Kingdom.
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Źródło :
Vascular and endovascular surgery [Vasc Endovascular Surg] 2020 Nov; Vol. 54 (8), pp. 712-717. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance*
Aspirin/*therapeutic use
Carotid Artery Diseases/*drug therapy
Clopidogrel/*therapeutic use
Infarction, Middle Cerebral Artery/*prevention & control
Intracranial Embolism/*prevention & control
Platelet Aggregation/*drug effects
Platelet Aggregation Inhibitors/*therapeutic use
Aspirin/adverse effects ; Carotid Artery Diseases/blood ; Carotid Artery Diseases/complications ; Carotid Artery Diseases/diagnostic imaging ; Clopidogrel/adverse effects ; Female ; Humans ; Infarction, Middle Cerebral Artery/diagnostic imaging ; Infarction, Middle Cerebral Artery/etiology ; Intracranial Embolism/diagnostic imaging ; Intracranial Embolism/etiology ; Male ; Platelet Aggregation Inhibitors/adverse effects ; Risk Factors ; Time Factors ; Treatment Outcome ; Ultrasonography, Doppler, Transcranial
Czasopismo naukowe
Tytuł :
Extended antiplatelet therapy with clopidogrel alone versus clopidogrel plus aspirin after completion of 9- to 12-month dual antiplatelet therapy for acute coronary syndrome patients with both high bleeding and ischemic risk. Rationale and design of the OPT-BIRISK double-blinded, placebo-controlled randomized trial.
Autorzy :
Li Y; Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China.
Jing Q; Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China.
Wang B; Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China.
Wang X; Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China.
Li J; Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China.
Qiao S; Fu Wai Hospital of Chinese Academy of Medical Science, Beijing, China.
Chen S; Nanjing First Hospital of Nanjing Medical University, Nanjing, China.
Angiolillo DJ; University of Florida College of Medicine-Jacksonville, Jacksonville, FL, USA.
Han Y; Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China. Electronic address: .
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Źródło :
American heart journal [Am Heart J] 2020 Oct; Vol. 228, pp. 1-7. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Clinical Trial Protocol; Journal Article
MeSH Terms :
Acute Coronary Syndrome*/complications
Acute Coronary Syndrome*/drug therapy
Acute Coronary Syndrome*/surgery
Aspirin*/administration & dosage
Aspirin*/adverse effects
Clopidogrel*/administration & dosage
Clopidogrel*/adverse effects
Hemorrhage*/chemically induced
Hemorrhage*/prevention & control
Stroke*/chemically induced
Stroke*/etiology
Stroke*/prevention & control
Risk Adjustment/*methods
Adult ; Double-Blind Method ; Drug-Eluting Stents/adverse effects ; Dual Anti-Platelet Therapy/adverse effects ; Dual Anti-Platelet Therapy/methods ; Female ; Humans ; Male ; Outcome and Process Assessment, Health Care ; Percutaneous Coronary Intervention/instrumentation ; Percutaneous Coronary Intervention/methods ; Platelet Aggregation Inhibitors/administration & dosage ; Platelet Aggregation Inhibitors/adverse effects ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Clinical outcomes of patients treated using very short duration dual antiplatelet therapy after implantation of biodegradable-polymer drug-eluting stents: rationale and design of a prospective multicenter REIWA registry.
Autorzy :
Ishida M; Division of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate, 020-3695, Japan. .
Takahashi F; Division of Medical Engineering, Department of Information Science, Iwate Medical University, Yahaba-cho, Iwate, Japan.
Goto I; Division of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate, 020-3695, Japan.
Niiyama M; Department of Cardiology, Hachinohe Red Cross Hospital, Hachinohe, Japan.
Saitoh H; Department of Cardiology, Iwate Prefectural Chubu Hospital, Kitakami, Japan.
Sakamoto T; Department of Cardiology, Iwate Prefectural Ofunato Hospital, Ofunato, Japan.
Maegawa Y; Department of Cardiology, Iwate Prefectural Miyako Hospital, Miyako, Japan.
Osaki T; Department of Cardiology, Iwate Prefectural Kuji Hospital, Kuji, Japan.
Nishiyama O; Department of Cardiology, Iwate Prefectural Ninohe Hospital, Ninohe, Japan.
Endo H; Department of Cardiology, Iwate Prefectural Iwai Hospital, Ichinoseki, Japan.
Sakamoto R; Department of Cardiology, Nakadori General Hospital, Akita, Japan.
Kojima T; Department of Cardiology, Morioka Red Cross Hospital, Morioka, Japan.
Koeda Y; Division of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate, 020-3695, Japan.
Kimura T; Division of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate, 020-3695, Japan.
Itoh T; Division of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate, 020-3695, Japan.
Morino Y; Division of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate, 020-3695, Japan.
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Corporate Authors :
REIWA investigators
Źródło :
Cardiovascular intervention and therapeutics [Cardiovasc Interv Ther] 2020 Oct; Vol. 35 (4), pp. 398-404. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article
MeSH Terms :
Drug-Eluting Stents*/adverse effects
Percutaneous Coronary Intervention*/adverse effects
Percutaneous Coronary Intervention*/instrumentation
Percutaneous Coronary Intervention*/methods
Clopidogrel/*administration & dosage
Coronary Artery Disease/*therapy
Platelet Aggregation Inhibitors/*administration & dosage
Prasugrel Hydrochloride/*administration & dosage
Absorbable Implants ; Clopidogrel/adverse effects ; Clopidogrel/therapeutic use ; Coronary Artery Disease/complications ; Coronary Artery Disease/drug therapy ; Drug Administration Schedule ; Drug Therapy, Combination/adverse effects ; Female ; Humans ; Male ; Middle Aged ; Myocardial Ischemia/drug therapy ; Myocardial Ischemia/etiology ; Myocardial Ischemia/therapy ; Observational Studies as Topic ; Platelet Aggregation Inhibitors/adverse effects ; Platelet Aggregation Inhibitors/therapeutic use ; Polymers ; Prasugrel Hydrochloride/adverse effects ; Prasugrel Hydrochloride/therapeutic use ; Prospective Studies ; Registries ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Ticagrelor Versus Clopidogrel in Patients with Late or Very Late Stent Thrombosis.
Autorzy :
Zhou J; Department of Coronary Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Tan Y; Department of Coronary Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Xiamen Cardiovascular Hospital, Xiamen University, Fujian, China.
Liu C; Department of Coronary Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhou P; Department of Coronary Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Sheng Z; Department of Coronary Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li J; Department of Coronary Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chen R; Department of Coronary Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhao H; Department of Coronary Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Song L; Department of Coronary Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yan H; Department of Coronary Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. .; Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, China. .
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Źródło :
Cardiovascular drugs and therapy [Cardiovasc Drugs Ther] 2020 Oct; Vol. 34 (5), pp. 677-684. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Comparative Study; Journal Article; Observational Study
MeSH Terms :
Stents*
Acute Coronary Syndrome/*therapy
Clopidogrel/*therapeutic use
Coronary Thrombosis/*prevention & control
Percutaneous Coronary Intervention/*instrumentation
Platelet Aggregation Inhibitors/*therapeutic use
Purinergic P2Y Receptor Antagonists/*therapeutic use
Ticagrelor/*therapeutic use
Acute Coronary Syndrome/diagnostic imaging ; Acute Coronary Syndrome/mortality ; Aged ; Clopidogrel/adverse effects ; Coronary Thrombosis/etiology ; Coronary Thrombosis/mortality ; Female ; Humans ; Male ; Middle Aged ; Percutaneous Coronary Intervention/adverse effects ; Percutaneous Coronary Intervention/mortality ; Platelet Aggregation Inhibitors/adverse effects ; Purinergic P2Y Receptor Antagonists/adverse effects ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Ticagrelor/adverse effects ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Optimal antiplatelet therapy for prevention of gastrointestinal injury evaluated by ANKON magnetically controlled capsule endoscopy: Rationale and design of the OPT-PEACE trial.
Autorzy :
Li Y; Department of Cardiology, General hospital of Northern Theater Command, Shenyang, China.
Wang X; Department of Cardiology, General hospital of Northern Theater Command, Shenyang, China.
Bao D; Department of Cardiology, General hospital of Northern Theater Command, Shenyang, China.
Liao Z; Digestive Endoscopy Center, Department of Gastroenterology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, China.
Li J; Department of Cardiology, General hospital of Northern Theater Command, Shenyang, China.
Han X; Department of Endoscopy, General hospital of Northern Theater Command, Shenyang, China.
Wang H; Department of Cardiology, General hospital of Northern Theater Command, Shenyang, China.
Xu K; Department of Cardiology, General hospital of Northern Theater Command, Shenyang, China.
Li Z; Digestive Endoscopy Center, Department of Gastroenterology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, China.
Stone GW; Icahn School of Medicine at Mount Sinai, Mount Sinai Heart and the Cardiovascular Research Foundation, New York.
Han Y; Department of Cardiology, General hospital of Northern Theater Command, Shenyang, China. Electronic address: .
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Źródło :
American heart journal [Am Heart J] 2020 Oct; Vol. 228, pp. 8-16. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Aspirin*/administration & dosage
Aspirin*/adverse effects
Clopidogrel*/administration & dosage
Clopidogrel*/adverse effects
Coronary Artery Disease*/diagnosis
Coronary Artery Disease*/drug therapy
Coronary Artery Disease*/surgery
Gastrointestinal Hemorrhage*/chemically induced
Gastrointestinal Hemorrhage*/diagnosis
Gastrointestinal Hemorrhage*/prevention & control
Percutaneous Coronary Intervention*/instrumentation
Capsule Endoscopy/*methods
Adult ; Coronary Angiography/methods ; Double-Blind Method ; Drug-Eluting Stents ; Dual Anti-Platelet Therapy/methods ; Female ; Humans ; Male ; Outcome and Process Assessment, Health Care ; Platelet Aggregation Inhibitors/administration & dosage ; Platelet Aggregation Inhibitors/adverse effects ; Randomized Controlled Trials as Topic ; Risk Adjustment/methods
Czasopismo naukowe
Tytuł :
Influences of Smoking Status on Effectiveness of Cytochrome P450 Enzyme System Metabolized Medications in Reducing In-Hospital Death in 14 658 Patients With Acute Myocardial Infarction: Data From CPACS-3 Study.
Autorzy :
Li M; Clinical Epidemiology and EBM Center, National Clinical Research Center for Digestive Diseases, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Feng L; Peking University Clinical Research Institute, Peking University Health Science Center, Beijing, China.
Li X; The George Institute for Global Health at Peking University Health Science Center, Beijing, China.
Gao R; Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wu Y; Peking University Clinical Research Institute, Peking University Health Science Center, Beijing, China.; The George Institute for Global Health at Peking University Health Science Center, Beijing, China.
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Źródło :
Journal of cardiovascular pharmacology and therapeutics [J Cardiovasc Pharmacol Ther] 2020 Sep; Vol. 25 (5), pp. 418-424. Date of Electronic Publication: 2020 Apr 26.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Hospital Mortality*
Smokers*
Clopidogrel/*therapeutic use
Cytochrome P-450 Enzyme System/*metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Myocardial Infarction/*drug therapy
Purinergic P2Y Receptor Antagonists/*therapeutic use
Smoking/*adverse effects
Aged ; Biotransformation ; Calcium Channel Blockers/metabolism ; Calcium Channel Blockers/therapeutic use ; China/epidemiology ; Clopidogrel/metabolism ; Female ; Hospitalization ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/metabolism ; Male ; Middle Aged ; Myocardial Infarction/mortality ; Non-Smokers ; Prospective Studies ; Purinergic P2Y Receptor Antagonists/metabolism ; Registries ; Risk Assessment ; Risk Factors ; Smoking/metabolism ; Smoking/mortality ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Search for a practical approach for detection of clopidogrel resistance: Comparison of light transmission aggregometry and INNOVANCE® PFA P2Y cartridge and correlation with CYP2C19 variants.
Autorzy :
Heireman L; Coagulation Laboratory, Department of Laboratory Medicine, University Hospital Ghent, Ghent, Belgium.
Monteyne T; Coagulation Laboratory, Department of Laboratory Medicine, University Hospital Ghent, Ghent, Belgium.
Hemelsoet D; Department of Neurology, University Hospital Ghent, Ghent, Belgium.
van Schaik RHN; Department of Clinical Chemistry, Erasmus Medical Centre, Rotterdam, The Netherlands.
Devreese KMJ; Coagulation Laboratory, Department of Laboratory Medicine, University Hospital Ghent, Ghent, Belgium.; Department of Diagnostic Sciences, Ghent University, Ghent, Belgium.
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Źródło :
International journal of laboratory hematology [Int J Lab Hematol] 2020 Aug; Vol. 42 (4), pp. e189-e191. Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Comparative Study; Letter
MeSH Terms :
Cardiovascular Diseases*/blood
Cardiovascular Diseases*/drug therapy
Cardiovascular Diseases*/genetics
Cardiovascular Diseases*/pathology
Clopidogrel*/administration & dosage
Clopidogrel*/pharmacokinetics
Blood Platelets/*enzymology
Cytochrome P-450 CYP2C19/*genetics
Drug Resistance/*genetics
Platelet Aggregation/*drug effects
Adult ; Aged ; Aged, 80 and over ; Blood Platelets/pathology ; Cytochrome P-450 CYP2C19/metabolism ; Drug Resistance/drug effects ; Female ; Humans ; Male ; Middle Aged ; Platelet Function Tests
Raport
Tytuł :
High on-clopidogrel platelet reactivity in ischaemic stroke or transient ischaemic attack: Systematic review and meta-analysis.
Autorzy :
Alakbarzade V; Royal Cornwall Hospitals NHS Trust, Neurology, Truro, United Kingdom; St George's University Hospitals NHS Trust, Neurology, London, United Kingdom. Electronic address: .
Huang X; St George's University Hospitals NHS Trust, Neurology, London, United Kingdom. Electronic address: .
Ster IC; Institute of Infection and Immunity, St. George's University of London, London, United Kingdom. Electronic address: .
McEntagart M; St George's University of London, Neuroscience, London, United Kingdom. Electronic address: .
Pereira AC; St George's University Hospitals NHS Trust, Neurology, London, United Kingdom. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Jul; Vol. 29 (7), pp. 104877. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Drug Resistance*/genetics
Blood Platelets/*drug effects
Clopidogrel/*therapeutic use
Ischemic Attack, Transient/*drug therapy
Platelet Aggregation/*drug effects
Platelet Aggregation Inhibitors/*therapeutic use
Stroke/*drug therapy
Blood Platelets/metabolism ; Clopidogrel/adverse effects ; Clopidogrel/pharmacokinetics ; Cytochrome P-450 CYP2C19/genetics ; Cytochrome P-450 CYP2C19/metabolism ; Humans ; Ischemic Attack, Transient/blood ; Ischemic Attack, Transient/diagnosis ; Pharmacogenomic Variants ; Platelet Aggregation Inhibitors/adverse effects ; Platelet Aggregation Inhibitors/pharmacokinetics ; Polymorphism, Genetic ; Risk Factors ; Stroke/blood ; Stroke/diagnosis ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Association of Ticagrelor vs Clopidogrel With Net Adverse Clinical Events in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.
Autorzy :
You SC; Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.; Observational Health Data Sciences and Informatics, New York, New York.
Rho Y; Observational Health Data Sciences and Informatics, New York, New York.; Health Insurance Review and Assessment Service, Wonju, Korea.
Bikdeli B; Observational Health Data Sciences and Informatics, New York, New York.; Division of Cardiology, Department of Medicine, Columbia University Medical Center/New York-Presbyterian Hospital, New York, New York.; Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, Connecticut.; Cardiovascular Research Foundation (CRF), New York, New York.
Kim J; Observational Health Data Sciences and Informatics, New York, New York.; Health Insurance Review and Assessment Service, Wonju, Korea.
Siapos A; Observational Health Data Sciences and Informatics, New York, New York.; Real World Evidence Solutions, IQVIA, Durham, North Carolina.
Weaver J; Observational Health Data Sciences and Informatics, New York, New York.; Epidemiology Analytics, Janssen Research and Development, Titusville, New Jersey.
Londhe A; Observational Health Data Sciences and Informatics, New York, New York.; Janssen Research and Development, Titusville, New Jersey.; Now with Amgen, Thousand Oaks, California.
Cho J; Observational Health Data Sciences and Informatics, New York, New York.; Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.
Park J; Observational Health Data Sciences and Informatics, New York, New York.; Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.
Schuemie M; Observational Health Data Sciences and Informatics, New York, New York.; Epidemiology Analytics, Janssen Research and Development, Titusville, New Jersey.; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles.
Suchard MA; Observational Health Data Sciences and Informatics, New York, New York.; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles.; Department of Biomathematics, David Geffen School of Medicine at UCLA, University of California, Los Angeles.
Madigan D; Observational Health Data Sciences and Informatics, New York, New York.; Department of Statistics, Columbia University, New York, New York.
Hripcsak G; Observational Health Data Sciences and Informatics, New York, New York.; Department of Biomedical Informatics, Columbia University, New York, New York.; Medical Informatics Services, New York-Presbyterian Hospital, New York, New York.
Gupta A; Observational Health Data Sciences and Informatics, New York, New York.; Division of Cardiology, Department of Medicine, Columbia University Medical Center/New York-Presbyterian Hospital, New York, New York.; Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, Connecticut.; Cardiovascular Research Foundation (CRF), New York, New York.
Reich CG; Observational Health Data Sciences and Informatics, New York, New York.; Real World Evidence Solutions, IQVIA, Durham, North Carolina.
Ryan PB; Observational Health Data Sciences and Informatics, New York, New York.; Epidemiology Analytics, Janssen Research and Development, Titusville, New Jersey.; Department of Biomedical Informatics, Columbia University, New York, New York.
Park RW; Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.; Observational Health Data Sciences and Informatics, New York, New York.; Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.
Krumholz HM; Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, Connecticut.; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.; Department of Health Policy and Management, Yale School of Public Health, New Haven, Connecticut.
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Źródło :
JAMA [JAMA] 2020 Oct 27; Vol. 324 (16), pp. 1640-1650.
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Percutaneous Coronary Intervention*
Acute Coronary Syndrome/*surgery
Clopidogrel/*adverse effects
Purinergic P2Y Receptor Antagonists/*adverse effects
Ticagrelor/*adverse effects
Acute Coronary Syndrome/mortality ; Adult ; Aged ; Aged, 80 and over ; Algorithms ; Aspirin/administration & dosage ; Case-Control Studies ; Cause of Death ; Clopidogrel/administration & dosage ; Databases, Factual/statistics & numerical data ; Dyspnea/chemically induced ; Female ; Hemorrhage/chemically induced ; Humans ; Ischemia/chemically induced ; Male ; Middle Aged ; Myocardial Infarction/epidemiology ; Network Meta-Analysis ; Propensity Score ; Purinergic P2Y Receptor Antagonists/administration & dosage ; Recurrence ; Republic of Korea ; Retrospective Studies ; Stroke/epidemiology ; Ticagrelor/administration & dosage ; United States
Czasopismo naukowe

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