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Tytuł:
Molecular characterizations of genes in chloroplast genomes of the genus Arachis L. (Fabaceae) based on the codon usage divergence.
Autorzy:
Yang S; School of Intelligent Science and Information Engineering, Xi'an Peihua University, Xi'An, Shaanxi, China.
Li G; Department of Biomedical Engineering, Laboratory for Biodiversity Science, School of Electronic Information Engineering, Xi'An Technological University, Xi'An, Shaanxi, China.
Li H; College of Food Engineering, Jilin Engineering Normal University, Changchun, Jilin, China.
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Źródło:
PloS one [PLoS One] 2023 Mar 14; Vol. 18 (3), pp. e0281843. Date of Electronic Publication: 2023 Mar 14 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arachis*/genetics
Codon Usage*
Genome, Chloroplast*
Codon/genetics ; Evolution, Molecular
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Calculating and comparing codon usage values in rare disease genes highlights codon clustering with disease-and tissue- specific hierarchy.
Autorzy:
Rossi R; Unit of Medical Genetics, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.; Dubowitz Neuromuscular Unit, Institute of Child Health, University College London, London, United Kingdom.
Fang M; BGI-Shenzhen, Shenzhen, China.
Zhu L; BGI-Shenzhen, Shenzhen, China.; BGI College & Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China.
Jiang C; BGI-Shenzhen, Shenzhen, China.
Yu C; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Flesia C; Department of Earth and Environment Science, University of Milano-Bicocca, Milano, Italy.
Nie C; BGI-Shenzhen, Shenzhen, China.
Li W; MGI, BGI-Shenzhen, Shenzhen, China.
Ferlini A; Unit of Medical Genetics, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.; Dubowitz Neuromuscular Unit, Institute of Child Health, University College London, London, United Kingdom.
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Źródło:
PloS one [PLoS One] 2022 Mar 31; Vol. 17 (3), pp. e0265469. Date of Electronic Publication: 2022 Mar 31 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Codon Usage*
Magnoliopsida*/genetics
Animals ; Cluster Analysis ; Codon/genetics ; Dystrophin/genetics ; Humans ; Mammals/genetics ; Rare Diseases/genetics ; Selection, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel anti-PTEN C2 domain monoclonal antibodies to analyse the expression and function of PTEN isoform variants.
Autorzy:
Torices L; Biobizkaia Health Research Institute, Barakaldo, Spain.
Nunes-Xavier CE; Biobizkaia Health Research Institute, Barakaldo, Spain.; Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
López JI; Biobizkaia Health Research Institute, Barakaldo, Spain.
Pulido R; Biobizkaia Health Research Institute, Barakaldo, Spain.; Ikerbasque, The Basque Foundation for Science, Bilbao, Spain.
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Źródło:
PloS one [PLoS One] 2023 Aug 01; Vol. 18 (8), pp. e0289369. Date of Electronic Publication: 2023 Aug 01 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Codon, Nonsense*
Neoplasms*
Humans ; C2 Domains ; PTEN Phosphohydrolase/genetics ; PTEN Phosphohydrolase/metabolism ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Germ-Line Mutation ; Epitopes ; Antibodies, Monoclonal/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
JUN mRNA translation regulation is mediated by multiple 5' UTR and start codon features.
Autorzy:
González-Sánchez AM; Comparative Biochemistry Graduate Program, University of California, Berkeley, Berkeley, CA, United States of America.
Castellanos-Silva EA; Department of Biochemistry and Molecular Biology, University of California, Davis, Davis, CA, United States of America.
Díaz-Figueroa G; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.
Cate JHD; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Mar 14; Vol. 19 (3), pp. e0299779. Date of Electronic Publication: 2024 Mar 14 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Eukaryotic Initiation Factor-3*/genetics
Eukaryotic Initiation Factor-3*/metabolism
Protein Biosynthesis*
Animals ; Humans ; Codon, Initiator/genetics ; 5' Untranslated Regions/genetics ; RNA, Messenger/metabolism ; Transcription Factors/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Unraveling the plasticity of translation initiation in prokaryotes: Beyond the invariant Shine-Dalgarno sequence.
Autorzy:
Estrada K; Centro de Investigación en Dinámica Celular, Instituto de Investigación en Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos (UAEM), Cuernavaca, Morelos, México.; Massive Sequencing and Bioinformatics Unit, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.
Garciarrubio A; Department of Cell Engineering and Biocatalysis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.
Merino E; Department of Molecular Microbiology, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.
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Źródło:
PloS one [PLoS One] 2024 Jan 11; Vol. 19 (1), pp. e0289914. Date of Electronic Publication: 2024 Jan 11 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Chain Initiation, Translational*/genetics
Prokaryotic Cells*/metabolism
Phylogeny ; Codon, Initiator/genetics ; Bacteria/metabolism ; RNA, Messenger/metabolism ; RNA, Ribosomal, 16S/genetics ; RNA, Ribosomal, 16S/metabolism ; Protein Biosynthesis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells.
Autorzy:
Li C; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Liu Z; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Anderson J; Department of Pediatrics, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Liu Z; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Tang L; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Li Y; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Peng N; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Chen J; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Liu X; Key Laboratory of Imaging Processing and Intelligent Control, School of Artificial Intelligence and Automation, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Fu L; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Townes TM; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Rowe SM; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Bedwell DM; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Guimbellot J; Department of Pediatrics, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Zhao R; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Gregory Fleming James Cystic Fibrosis Research Center, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Nov 29; Vol. 18 (11), pp. e0295009. Date of Electronic Publication: 2023 Nov 29 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Induced Pluripotent Stem Cells*
Cystic Fibrosis*/therapy
Cystic Fibrosis*/drug therapy
Humans ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Mutation ; Codon, Nonsense ; Epithelial Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genetic diversity, haplotype analysis, and prevalence of Hepatitis B virus MHR mutations among isolates from Kenyan blood donors.
Autorzy:
Langat BK; Department of Medical Biochemistry, University of Nairobi, Nairobi, Kenya.
Ochwedo KO; Department of Biology, Faculty of Science and Technology, University of Nairobi, Nairobi, Kenya.
Borlang J; National Microbiology Laboratory, Winnipeg, Canada.
Osiowy C; National Microbiology Laboratory, Winnipeg, Canada.
Mutai A; Kenya National Blood Transfusion Services, Nairobi, Kenya.
Okoth F; Centre for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya.
Muge E; Department of Medical Biochemistry, University of Nairobi, Nairobi, Kenya.
Andonov A; National Microbiology Laboratory, Winnipeg, Canada.
Maritim ES; Centre for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya.
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Źródło:
PloS one [PLoS One] 2023 Nov 14; Vol. 18 (11), pp. e0291378. Date of Electronic Publication: 2023 Nov 14 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hepatitis B virus*
Hepatitis B*/epidemiology
Hepatitis B*/genetics
Hepatitis B*/diagnosis
Male ; Humans ; Adult ; Female ; Kenya/epidemiology ; Hepatitis B Surface Antigens/genetics ; Haplotypes ; Blood Donors ; Prevalence ; Phylogeny ; DNA, Viral/genetics ; Mutation ; Genotype ; Nucleotides ; Codon
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pharmacological induction of translational readthrough of nonsense mutations in the retinoblastoma (RB1) gene.
Autorzy:
Palomar-Siles M; Department of Oncology-Pathology, BioClinicum, Karolinska Institutet, Stockholm, Sweden.
Yurevych V; Department of Oncology-Pathology, BioClinicum, Karolinska Institutet, Stockholm, Sweden.
Bykov VJN; Department of Oncology-Pathology, BioClinicum, Karolinska Institutet, Stockholm, Sweden.
Wiman KG; Department of Oncology-Pathology, BioClinicum, Karolinska Institutet, Stockholm, Sweden.
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Źródło:
PloS one [PLoS One] 2023 Nov 02; Vol. 18 (11), pp. e0292468. Date of Electronic Publication: 2023 Nov 02 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Retinoblastoma*/genetics
Retinal Neoplasms*/pathology
Humans ; Codon, Nonsense/genetics ; Retinoblastoma Protein/genetics ; Protein Biosynthesis ; Ubiquitin-Protein Ligases/genetics ; Retinoblastoma Binding Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Optimized approach for the identification of highly efficient correctors of nonsense mutations in human diseases.
Autorzy:
Benhabiles H; Univ. Lille, CNRS, Institut Pasteur de Lille, UMR 8161-M3T -Mechanisms of Tumorigenesis and Target Therapies, Lille, France.
Gonzalez-Hilarion S; Univ. Lille, CNRS, Institut Pasteur de Lille, UMR 8161-M3T -Mechanisms of Tumorigenesis and Target Therapies, Lille, France.
Amand S; Muséum National d'Histoire Naturelle, Sorbonne Universités, Centre National de la Recherche Scientifique, Laboratoire Molécules de Communication et Adaptation des Microorganismes (MCAM), UMR 7245 CNRS-MNHN, CP 54, Paris, France.
Bailly C; Muséum National d'Histoire Naturelle, Sorbonne Universités, Centre National de la Recherche Scientifique, Laboratoire Molécules de Communication et Adaptation des Microorganismes (MCAM), UMR 7245 CNRS-MNHN, CP 54, Paris, France.
Prévotat A; Univ. Lille, Clinique des Maladies Respiratoires, CRCM Hôpital Calmette, CHRU Lille, France.
Reix P; Hospices Civils de Lyon, Centre de Référence Mucoviscidose, Lyon, France.
Hubert D; Pulmonary Department and Adult CF Centre, Cochin Hospital, AP-HP, Paris, France.
Adriaenssens E; INSERM U908, Cell plasticity and Cancer, University of Lille, Villeneuve d'Ascq, France.
Rebuffat S; Muséum National d'Histoire Naturelle, Sorbonne Universités, Centre National de la Recherche Scientifique, Laboratoire Molécules de Communication et Adaptation des Microorganismes (MCAM), UMR 7245 CNRS-MNHN, CP 54, Paris, France.
Tulasne D; Univ. Lille, CNRS, Institut Pasteur de Lille, UMR 8161-M3T -Mechanisms of Tumorigenesis and Target Therapies, Lille, France.
Lejeune F; Univ. Lille, CNRS, Institut Pasteur de Lille, UMR 8161-M3T -Mechanisms of Tumorigenesis and Target Therapies, Lille, France.
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Źródło:
PloS one [PLoS One] 2017 Nov 13; Vol. 12 (11), pp. e0187930. Date of Electronic Publication: 2017 Nov 13 (Print Publication: 2017).
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Codon, Nonsense*
Genetic Predisposition to Disease*
Base Sequence ; Codon, Terminator ; Cystic Fibrosis/genetics ; Cystic Fibrosis/therapy ; HeLa Cells ; Humans ; Nonsense Mediated mRNA Decay ; RNA, Messenger/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Is the tryptophan codon of gene vif the Achilles' heel of HIV-1?
Autorzy:
Villanova F; Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.
Barreiros M; Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.
Leal É; Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.
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Źródło:
PloS one [PLoS One] 2020 Jun 22; Vol. 15 (6), pp. e0225563. Date of Electronic Publication: 2020 Jun 22 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tryptophan*
Codon/*genetics
HIV-1/*genetics
vif Gene Products, Human Immunodeficiency Virus/*genetics
CD4 Lymphocyte Count ; Codon, Terminator/genetics ; HIV-1/physiology ; Mutation ; Viral Load/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of computational codon usage models and their association with translationally slow codons.
Autorzy:
Wright G; Department of Computer Science & Engineering, University of Notre Dame, Notre Dame, IN, United States of America.
Rodriguez A; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN, United States of America.
Li J; Department of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN, United States of America.
Clark PL; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN, United States of America.
Milenković T; Department of Computer Science & Engineering, University of Notre Dame, Notre Dame, IN, United States of America.
Emrich SJ; Department of Electrical Engineering & Computer Science, University of Tennessee, Knoxville, TN, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Apr 30; Vol. 15 (4), pp. e0232003. Date of Electronic Publication: 2020 Apr 30 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Codon Usage/*genetics
Computational Biology/*methods
Protein Biosynthesis/*physiology
Codon/genetics ; Databases, Genetic ; Models, Theoretical ; Protein Biosynthesis/genetics ; RNA, Messenger/genetics ; Ribosomes/genetics ; Saccharomyces cerevisiae/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exploring the evolution and function of Canoe's intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis.
Autorzy:
Gurley NJ; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Szymanski RA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Dowen RH; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.; Integrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Butcher TA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Ishiyama N; Launchpad Therapeutics, Inc., Cambridge, MA, United States of America.
Peifer M; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Aug 03; Vol. 18 (8), pp. e0289224. Date of Electronic Publication: 2023 Aug 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Drosophila Proteins*/genetics
Drosophila Proteins*/metabolism
Intrinsically Disordered Proteins*/genetics
Animals ; Actins/metabolism ; Adherens Junctions/metabolism ; Codon, Terminator ; Cytoskeleton/metabolism ; Drosophila melanogaster/metabolism ; Embryonic Development ; Intercellular Junctions/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nucleotide composition affects codon usage toward the 3'-end.
Autorzy:
Zahdeh F; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, Israel.; Hereditary Research Lab, Life Sciences Department, Bethlehem University, Bethlehem, Palestinian authority.
Carmel L; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, Israel.
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Źródło:
PloS one [PLoS One] 2019 Dec 04; Vol. 14 (12), pp. e0225633. Date of Electronic Publication: 2019 Dec 04 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Base Composition/*genetics
Codon Usage/*genetics
Nucleotides/*genetics
Bias ; Codon/genetics ; Gene Expression Regulation ; Humans ; RNA Folding ; RNA, Messenger/chemistry ; RNA, Messenger/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Complete chloroplast genome of Hordeum brevisubulatum: Genome organization, synonymous codon usage, phylogenetic relationships, and comparative structure analysis.
Autorzy:
Cui G; Lanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Wang C; Lanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Wei X; Academy of Animal and Veterinary Sciences, Qinghai University, Xining, Qinghai, China.
Wang H; Lanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.; Laboratory of Quality & Safety Risk Assessment for Livestock Products, Ministry of Agriculture and Rural Affairs, Lanzhou, Gansu, China.
Wang X; Lanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Zhu X; Lanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Li J; Lanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Yang H; Lanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Duan H; Lanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
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Źródło:
PloS one [PLoS One] 2021 Dec 13; Vol. 16 (12), pp. e0261196. Date of Electronic Publication: 2021 Dec 13 (Print Publication: 2021).
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Codon Usage*
Evolution, Molecular*
Genome, Chloroplast*
Phylogeny*
Chromosomes, Plant/*genetics
Hordeum/*genetics
Chloroplasts ; Genes, Plant ; Introns ; Molecular Sequence Annotation ; Open Reading Frames
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Gene mining, codon optimization and analysis of binding mechanism of an aldo-keto reductase with high activity, better substrate specificity and excellent solvent tolerance.
Autorzy:
Jiang W; College of Chemical Engineering, Huaqiao University, Xiamen, China.
Fu X; College of Chemical Engineering, Huaqiao University, Xiamen, China.
Wu W; College of Chemical Engineering, Huaqiao University, Xiamen, China.
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Źródło:
PloS one [PLoS One] 2021 Dec 02; Vol. 16 (12), pp. e0260787. Date of Electronic Publication: 2021 Dec 02 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Codon*
Alcohols/*metabolism
Aldo-Keto Reductases/*metabolism
Candida tropicalis/*enzymology
Fungal Proteins/*metabolism
Solvents/*chemistry
Aldo-Keto Reductases/chemistry ; Aldo-Keto Reductases/genetics ; Binding Sites ; Catalysis ; Fungal Proteins/chemistry ; Fungal Proteins/genetics ; Substrate Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential.
Autorzy:
Friesen WJ; PTC Therapeutics, South Plainfield, NJ, United States of America.
Johnson B; PTC Therapeutics, South Plainfield, NJ, United States of America.
Sierra J; PTC Therapeutics, South Plainfield, NJ, United States of America.
Zhuo J; PTC Therapeutics, South Plainfield, NJ, United States of America.
Vazirani P; PTC Therapeutics, South Plainfield, NJ, United States of America.
Xue X; PTC Therapeutics, South Plainfield, NJ, United States of America.
Tomizawa Y; PTC Therapeutics, South Plainfield, NJ, United States of America.
Baiazitov R; PTC Therapeutics, South Plainfield, NJ, United States of America.
Morrill C; PTC Therapeutics, South Plainfield, NJ, United States of America.
Ren H; PTC Therapeutics, South Plainfield, NJ, United States of America.
Babu S; PTC Therapeutics, South Plainfield, NJ, United States of America.
Moon YC; PTC Therapeutics, South Plainfield, NJ, United States of America.
Branstrom A; PTC Therapeutics, South Plainfield, NJ, United States of America.
Mollin A; PTC Therapeutics, South Plainfield, NJ, United States of America.
Hedrick J; PTC Therapeutics, South Plainfield, NJ, United States of America.
Sheedy J; PTC Therapeutics, South Plainfield, NJ, United States of America.
Elfring G; PTC Therapeutics, South Plainfield, NJ, United States of America.
Weetall M; PTC Therapeutics, South Plainfield, NJ, United States of America.
Colacino JM; PTC Therapeutics, South Plainfield, NJ, United States of America.
Welch EM; PTC Therapeutics, South Plainfield, NJ, United States of America.
Peltz SW; PTC Therapeutics, South Plainfield, NJ, United States of America.
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Źródło:
PloS one [PLoS One] 2018 Oct 25; Vol. 13 (10), pp. e0206158. Date of Electronic Publication: 2018 Oct 25 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Codon, Nonsense/*chemical synthesis
Genetic Diseases, Inborn/*drug therapy
Gentamicins/*pharmacology
Protein Synthesis Inhibitors/*pharmacology
Aminoglycosides/pharmacology ; Aminoglycosides/therapeutic use ; Animals ; Antibiotics, Antineoplastic/pharmacology ; Cells, Cultured ; Codon, Terminator/chemical synthesis ; Embryo, Nonmammalian ; Gentamicins/chemistry ; Gentamicins/therapeutic use ; Humans ; Kidney Diseases/chemically induced ; Kidney Diseases/pathology ; Male ; Open Reading Frames/drug effects ; Open Reading Frames/genetics ; Protein Synthesis Inhibitors/therapeutic use ; Rats ; Rats, Sprague-Dawley ; Zebrafish/embryology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synonymous codon usage bias in plant mitochondrial genes is associated with intron number and mirrors species evolution.
Autorzy:
Xu W; The Key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, School of Life Science, Shandong University, 27 Shandanan Road, Jinan, Shandong 250100, China.
Xing T; The Key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, School of Life Science, Shandong University, 27 Shandanan Road, Jinan, Shandong 250100, China.
Zhao M; The Key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, School of Life Science, Shandong University, 27 Shandanan Road, Jinan, Shandong 250100, China.
Yin X; The Key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, School of Life Science, Shandong University, 27 Shandanan Road, Jinan, Shandong 250100, China.
Xia G; The Key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, School of Life Science, Shandong University, 27 Shandanan Road, Jinan, Shandong 250100, China.
Wang M; The Key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, School of Life Science, Shandong University, 27 Shandanan Road, Jinan, Shandong 250100, China.
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Źródło:
PloS one [PLoS One] 2015 Jun 25; Vol. 10 (6), pp. e0131508. Date of Electronic Publication: 2015 Jun 25 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Codon*
Genes, Mitochondrial*
Genes, Plant*
Introns*
Plants/*genetics
Biological Evolution ; Chloroplasts/genetics ; Codon, Terminator ; DNA, Mitochondrial/genetics ; Evolution, Molecular ; Exons ; Gene Frequency ; Phylogeny ; Plastids/genetics ; Species Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The effect of the genomic GC content bias of prokaryotic organisms on the secondary structures of their proteins.
Autorzy:
Barceló-Antemate D; Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.; Centro de Investigación en Dinámica Celular, Instituto de Investigación en Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos (UAEM), Cuernavaca, Morelos, México.
Fontove-Herrera F; C3 Consensus, León, Guanajuato, México.
Santos W; Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.
Merino E; Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México.
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Źródło:
PloS one [PLoS One] 2023 May 04; Vol. 18 (5), pp. e0285201. Date of Electronic Publication: 2023 May 04 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proteome*/genetics
Amino Acids*/chemistry
Base Composition ; Phylogeny ; Genomics ; Codon/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Polyploidization is accompanied by synonymous codon usage bias in the chloroplast genomes of both cotton and wheat.
Autorzy:
Tian G; The Key Laboratory of Plant Development and Environmental Adaption, Ministry of Education, School of Life Science, Shandong University, Jinan, Shandong, China.
Li G; The Key Laboratory of Plant Development and Environmental Adaption, Ministry of Education, School of Life Science, Shandong University, Jinan, Shandong, China.
Liu Y; The Key Laboratory of Plant Development and Environmental Adaption, Ministry of Education, School of Life Science, Shandong University, Jinan, Shandong, China.
Liu Q; The Key Laboratory of Plant Development and Environmental Adaption, Ministry of Education, School of Life Science, Shandong University, Jinan, Shandong, China.
Wang Y; Shijiazhuang Academy of Agriculture and Forestry Sciences, Shijiazhuang, China.
Xia G; The Key Laboratory of Plant Development and Environmental Adaption, Ministry of Education, School of Life Science, Shandong University, Jinan, Shandong, China.
Wang M; The Key Laboratory of Plant Development and Environmental Adaption, Ministry of Education, School of Life Science, Shandong University, Jinan, Shandong, China.
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Źródło:
PloS one [PLoS One] 2020 Nov 19; Vol. 15 (11), pp. e0242624. Date of Electronic Publication: 2020 Nov 19 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Codon*
Codon Usage*
Genome, Chloroplast*
Polyploidy*
Gossypium/*genetics
Triticum/*genetics
Exons
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Complete chloroplast genome features and phylogenetic analysis of Eruca sativa (Brassicaceae).
Autorzy:
Zhu B; School of Life Sciences, Guizhou Normal University, Guiyang, China.; Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan, China.
Qian F; School of Life Sciences, Guizhou Normal University, Guiyang, China.
Hou Y; School of Life Sciences, Guizhou Normal University, Guiyang, China.
Yang W; School of Life Sciences, Guizhou Normal University, Guiyang, China.
Cai M; School of Life Sciences, Guizhou Normal University, Guiyang, China.
Wu X; Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan, China.
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Źródło:
PloS one [PLoS One] 2021 Mar 12; Vol. 16 (3), pp. e0248556. Date of Electronic Publication: 2021 Mar 12 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Codon Usage*
Evolution, Molecular*
Genome, Chloroplast*
Phylogeny*
Brassicaceae/*genetics
Brassicaceae/classification ; Chloroplast Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 839

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