Autor: "Cole AL" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Antimicrobial polypeptides are key anti-HIV-1 effector molecules of cervicovaginal host defense.
Autorzy:: Cole AM; Department of Molecular Biology and Microbiology, University of Central Florida, Orlando, FL, USA. />Cole AL; Pokaż więcej
Źródło:: American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2008 Jan; Vol. 59 (1), pp. 27-34.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:: Antimicrobial Cationic Peptides/*immunology
Cervix Uteri/*immunology
Defensins/*immunology
HIV Infections/*immunology
HIV-1/*immunology
Vagina/*immunology
Bacteria/immunology ; Cervix Uteri/microbiology ; Cervix Uteri/virology ; Defensins/metabolism ; Female ; HIV Infections/prevention & control ; HIV Infections/virology ; Humans ; Immunity, Innate ; Mucous Membrane/immunology ; Mucous Membrane/metabolism ; Vagina/microbiology ; Vagina/virology

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Skocz do pozycji: 2.

Tytuł:: The retrocyclin analogue RC-101 prevents human immunodeficiency virus type 1 infection of a model human cervicovaginal tissue construct.
Autorzy:: Cole AL; Department of Molecular Biology & Microbiology, Biomolecular Science Center, Burnett College of Biomedical Sciences at University of Central Florida, Orlando, FL 32816, USA. />Herasimtschuk A
Gupta P
Waring AJ
Lehrer RI
Cole AM; Pokaż więcej
Źródło:: Immunology [Immunology] 2007 May; Vol. 121 (1), pp. 140-5. Date of Electronic Publication: 2007 Jan 23.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Anti-HIV Agents/*pharmacology
HIV Infections/*virology
HIV-1/*drug effects
Peptides/*pharmacology
Vagina/*virology
Anti-HIV Agents/pharmacokinetics ; Anti-HIV Agents/toxicity ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Female ; Humans ; Inflammation Mediators/metabolism ; Models, Biological ; Peptides/pharmacokinetics ; Peptides/toxicity ; Tissue Culture Techniques ; Vagina/drug effects

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Skocz do pozycji: 3.

Tytuł:: Avirulins, a Novel Class of HIV-1 Reverse Transcriptase Inhibitors Effective in the Female Reproductive Tract Mucosa.
Autorzy:: Cherne MD; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, USA. michelle_.
Hall J; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, USA. .
Kellner A; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, USA. .
Chong CF; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, USA. .
Cole AL; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, USA. amy.cole@ucf.edu.
Cole AM; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32816, USA. .; Pokaż więcej
Źródło:: Viruses [Viruses] 2019 May 01; Vol. 11 (5). Date of Electronic Publication: 2019 May 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genitalia, Female*
HIV Infections/*virology
HIV-1/*drug effects
Mucous Membrane/*virology
Reverse Transcriptase Inhibitors/*pharmacology
Cell Line ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Discovery ; Drug Evaluation, Preclinical ; Female ; Genotype ; HIV Infections/drug therapy ; HIV Infections/transmission ; HIV-1/genetics ; Humans ; Mutation ; Reverse Transcriptase Inhibitors/therapeutic use

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Skocz do pozycji: 4.

Tytuł:: HIV-Enhancing and HIV-Inhibiting Properties of Cationic Peptides and Proteins.
Autorzy:: Cole AM; Division of Molecular Microbiology, Burnett School of Biomedical Sciences, UCF College of Medicine, 4110 Libra Drive, Orlando, FL 32816, USA. .
Cole AL; Division of Molecular Microbiology, Burnett School of Biomedical Sciences, UCF College of Medicine, 4110 Libra Drive, Orlando, FL 32816, USA. amy.cole@ucf.edu.; Pokaż więcej
Źródło:: Viruses [Viruses] 2017 May 15; Vol. 9 (5). Date of Electronic Publication: 2017 May 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Antimicrobial Cationic Peptides/*immunology
HIV Infections/*immunology
HIV-1/*drug effects
HIV-1/*immunology
Antimicrobial Cationic Peptides/pharmacology ; Antiviral Agents/pharmacology ; Female ; HIV Infections/prevention & control ; HIV Infections/virology ; HIV-1/pathogenicity ; Humans ; Immunity, Innate ; Mucous Membrane/immunology ; Mucous Membrane/virology ; Semen/virology ; Vagina/immunology ; Vagina/virology

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Skocz do pozycji: 5.

Tytuł:: Non-Cationic Proteins Are Associated with HIV Neutralizing Activity in Genital Secretions of Female Sex Workers.
Autorzy:: Birse KD; Proteomics Unit, National Laboratory for HIV Immunology, JC Wilt Infectious Disease Research Centre, Public Health Agency of Canada, Winnipeg, Manitoba, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada.
Cole AL; Burnett School of Biomedical Sciences, University of Central Florida College of Medicine, Orlando, Florida, United States of America.
Hirbod T; Unit of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
McKinnon L; Centre for the AIDS Programme of Research In South Africa, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Congella, South Africa.
Ball TB; Proteomics Unit, National Laboratory for HIV Immunology, JC Wilt Infectious Disease Research Centre, Public Health Agency of Canada, Winnipeg, Manitoba, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Medical Microbiology, Kenyatta National Hospital, University of Nairobi, Nairobi, Kenya.
Westmacott GR; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Kimani J; Department of Medical Microbiology, Kenyatta National Hospital, University of Nairobi, Nairobi, Kenya.
Plummer F; Proteomics Unit, National Laboratory for HIV Immunology, JC Wilt Infectious Disease Research Centre, Public Health Agency of Canada, Winnipeg, Manitoba, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada; Department of Medical Microbiology, Kenyatta National Hospital, University of Nairobi, Nairobi, Kenya.
Cole AM; Burnett School of Biomedical Sciences, University of Central Florida College of Medicine, Orlando, Florida, United States of America.
Burgener A; Proteomics Unit, National Laboratory for HIV Immunology, JC Wilt Infectious Disease Research Centre, Public Health Agency of Canada, Winnipeg, Manitoba, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada; Unit of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Broliden K; Unit of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Jun 19; Vol. 10 (6), pp. e0130404. Date of Electronic Publication: 2015 Jun 19 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Bodily Secretions/*immunology
HIV Infections/*immunology
Proteins/*metabolism
Vagina/*metabolism
Disease Susceptibility ; Female ; Humans ; Immunity, Innate ; Leukocytes, Mononuclear/virology ; Protective Factors ; Sex Workers ; Vagina/immunology ; Vagina/virology

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Skocz do pozycji: 6.

Tytuł:: The anti-HIV microbicide candidate RC-101 inhibits pathogenic vaginal bacteria without harming endogenous flora or mucosa.
Autorzy:: Eade CR; Burnett School of Biomedical Sciences, University of Central Florida College of Medicine, Orlando, FL 32816, USA.
Cole AL
Diaz C
Rohan LC
Parniak MA
Marx P
Tarwater PM
Gupta P
Cole AM; Pokaż więcej
Źródło:: American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2013 Feb; Vol. 69 (2), pp. 150-8. Date of Electronic Publication: 2012 Nov 20.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Anti-HIV Agents/*pharmacology
Peptides/*pharmacology
Vagina/*drug effects
Vagina/*microbiology
Vaginosis, Bacterial/*drug therapy
Vaginosis, Bacterial/*microbiology
Female ; Gardnerella vaginalis/drug effects ; Gardnerella vaginalis/pathogenicity ; HeLa Cells ; Humans ; Lactobacillus/drug effects ; Microbial Sensitivity Tests ; Mobiluncus/drug effects ; Mobiluncus/pathogenicity ; Prevotella/drug effects ; Symbiosis/drug effects

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Skocz do pozycji: 7.

Tytuł:: HIV-neutralizing activity of cationic polypeptides in cervicovaginal secretions of women in HIV-serodiscordant relationships.
Autorzy:: Levinson P; Unit of Infectious Diseases, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Choi RY
Cole AL
Hirbod T
Rhedin S
Payne B
Guthrie BL
Bosire R
Cole AM
Farquhar C
Broliden K; Pokaż więcej
Źródło:: PloS one [PLoS One] 2012; Vol. 7 (2), pp. e31996. Date of Electronic Publication: 2012 Feb 28.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cervix Mucus/*chemistry
HIV/*drug effects
HIV Infections/*immunology
Peptides/*immunology
Peptides/*metabolism
Vagina/*metabolism
Cervix Mucus/immunology ; Female ; HIV Seropositivity ; Humans ; Male ; Prospective Studies ; Vagina/immunology

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Skocz do pozycji: 8.

Tytuł:: HIV-1 enhancing effect of prostatic acid phosphatase peptides is reduced in human seminal plasma.
Autorzy:: Martellini JA; Department of Molecular Biology & Microbiology, Biomolecular Science Center, Burnett School of Biomedical Sciences at the University of Central Florida College of Medicine, Orlando, Florida, United States of America.
Cole AL
Svoboda P
Stuchlik O
Chen LM
Chai KX
Gangrade BK
Sørensen OE
Pohl J
Cole AM; Pokaż więcej
Źródło:: PloS one [PLoS One] 2011 Jan 20; Vol. 6 (1), pp. e16285. Date of Electronic Publication: 2011 Jan 20.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: HIV-1/*physiology
Peptide Fragments/*pharmacology
Protein Tyrosine Phosphatases/*pharmacology
Semen/*virology
Acid Phosphatase ; Amyloid ; Dose-Response Relationship, Drug ; HIV Enhancer ; HIV-1/drug effects ; Humans ; Prostate-Specific Antigen/metabolism ; Serine Endopeptidases/metabolism

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Skocz do pozycji: 9.

Tytuł:: Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin.
Autorzy:: Micewicz ED; Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, United States of America.
Cole AL
Jung CL
Luong H
Phillips ML
Pratikhya P
Sharma S
Waring AJ
Cole AM
Ruchala P; Pokaż więcej
Źródło:: PloS one [PLoS One] 2010 Dec 16; Vol. 5 (12), pp. e14360. Date of Electronic Publication: 2010 Dec 16.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Algal Proteins/*chemistry
HIV Infections/*prevention & control
HIV-1/*metabolism
Lectins/*chemistry
Rhodophyta/*metabolism
Amino Acid Sequence ; Disulfides/chemistry ; Drug Design ; HIV Core Protein p24/chemistry ; HIV Fusion Inhibitors/pharmacology ; Humans ; Molecular Sequence Data ; Peptides/chemistry ; Plant Proteins ; Protein Conformation ; Protein Structure, Secondary ; Sequence Homology, Amino Acid

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Skocz do pozycji: 10.

Tytuł:: Reawakening retrocyclins: ancestral human defensins active against HIV-1.
Autorzy:: Venkataraman N; Department of Molecular Biology and Microbiology, Burnett College of Biomedical Sciences, University of Central Florida, Orlando, Florida, United States of America.
Cole AL
Ruchala P
Waring AJ
Lehrer RI
Stuchlik O
Pohl J
Cole AM; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2009 Apr 28; Vol. 7 (4), pp. e95.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Aminoglycosides/*pharmacology
Defensins/*biosynthesis
HIV-1/*immunology
Amino Acid Sequence ; Cervix Uteri/metabolism ; Codon, Nonsense ; Defensins/genetics ; Epithelial Cells/metabolism ; Female ; Gene Expression Regulation ; Granulocyte Precursor Cells ; HIV Infections/prevention & control ; HIV Infections/transmission ; HL-60 Cells ; Humans ; RNA, Messenger/immunology ; RNA, Messenger/metabolism ; Transfection ; Vagina/metabolism

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