Temat: "Collagen Type VII" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Visualization of autoantibodies and neutrophils in vivo identifies novel checkpoints in autoantibody-induced tissue injury.
Autorzy:: Hundt JE; Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
Iwata H; Department of Dermatology, University of Lübeck, Lübeck, Germany.; Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Pieper M; Insitute of Anatomy, University of Lübeck, Germany and Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Lübeck, Germany. .
Pfündl R; Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
Bieber K; Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
Zillikens D; Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.; Department of Dermatology, University of Lübeck, Lübeck, Germany.
König P; Insitute of Anatomy, University of Lübeck, Germany and Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Lübeck, Germany.
Ludwig RJ; Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.; Department of Dermatology, University of Lübeck, Lübeck, Germany.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Mar 11; Vol. 10 (1), pp. 4509. Date of Electronic Publication: 2020 Mar 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Autoantibodies/*immunology
Disease Susceptibility/*immunology
Neutrophils/*immunology
Animals ; Autoimmune Diseases/etiology ; Autoimmune Diseases/metabolism ; Autoimmune Diseases/pathology ; Biomarkers ; Biopsy ; Collagen Type VII/immunology ; Disease Models, Animal ; Fluorescent Antibody Technique ; Immunoglobulin G/immunology ; Mice ; Neutrophils/metabolism ; Skin/immunology ; Skin/metabolism ; Skin/pathology

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Skocz do pozycji: 2.

Tytuł:: Structural proteins of the dermal-epidermal junction targeted by autoantibodies in pemphigoid diseases.
Autorzy:: Goletz S; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Lübeck, Germany.
Zillikens D; Department of Dermatology, University of Lübeck, Lübeck, Germany.
Schmidt E; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Lübeck, Germany.; Department of Dermatology, University of Lübeck, Lübeck, Germany.; Pokaż więcej
Źródło:: Experimental dermatology [Exp Dermatol] 2017 Dec; Vol. 26 (12), pp. 1154-1162.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Autoantibodies/*immunology
Skin Diseases, Vesiculobullous/*immunology
Animals ; Autoantigens/immunology ; Collagen Type VII/immunology ; Dystonin/immunology ; Humans ; Integrin alpha6beta4/immunology ; Laminin/immunology ; Non-Fibrillar Collagens/immunology ; Plectin/immunology ; Collagen Type XVII

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Skocz do pozycji: 3.

Tytuł:: T cells mediate autoantibody-induced cutaneous inflammation and blistering in epidermolysis bullosa acquisita.
Autorzy:: Bieber K; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
Witte M; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
Sun S; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.; Department of Immunology, Dalian Medical University, No9 West Section Lvshun S Rd, Liaoning Province, China.
Hundt JE; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
Kalies K; Institute of Anatomy, University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
Dräger S; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
Kasprick A; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
Twelkmeyer T; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.; Department of Dermatology, Johannes Gutenberg-University Mainz, Saarstraße 21, D-55122 Mainz, Germany.
Manz RA; ISEF, University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
König P; Institute of Anatomy, University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
Köhl J; ISEF, University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
Zillikens D; Department of Dermatology, University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
Ludwig RJ; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.; Department of Dermatology, University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Dec 05; Vol. 6, pp. 38357. Date of Electronic Publication: 2016 Dec 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Autoantibodies/*biosynthesis
Epidermolysis Bullosa Acquisita/*immunology
Natural Killer T-Cells/*immunology
Neutrophils/*immunology
Skin/*immunology
T-Lymphocytes/*immunology
Animals ; Antibodies, Monoclonal/administration & dosage ; Antigen-Antibody Complex/chemistry ; Antigen-Antibody Complex/metabolism ; Cell Communication/immunology ; Collagen Type VII/genetics ; Collagen Type VII/immunology ; Cricetulus ; Disease Models, Animal ; Epidermolysis Bullosa Acquisita/chemically induced ; Epidermolysis Bullosa Acquisita/pathology ; Gene Expression ; Humans ; Immunoglobulin G/biosynthesis ; Lymph Nodes/immunology ; Lymph Nodes/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Nude ; Natural Killer T-Cells/pathology ; Neutrophils/pathology ; Rabbits ; Receptors, Antigen, T-Cell, gamma-delta/genetics ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; Signal Transduction ; Skin/pathology ; Spleen/immunology ; Spleen/pathology ; T-Lymphocytes/pathology

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Skocz do pozycji: 4.

Tytuł:: Autoimmunity and Cytokine Imbalance in Inherited Epidermolysis Bullosa.
Autorzy:: Esposito S; Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy. .
Guez S; Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy. sguez_.
Orenti A; Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy. .
Tadini G; Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy. .; Dermatology Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy. .
Scuvera G; Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy. .
Corti L; Dermatology Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy. .
Scala A; Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy. .
Biganzoli E; Unit of Medical Statistics, Biometry and Bioinformatics 'G.A. Maccacaro', Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan 20122, Italy. .
Berti E; Dermatology Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy. .
Principi N; Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2016 Sep 24; Vol. 17 (10). Date of Electronic Publication: 2016 Sep 24.
Typ publikacji:: Journal Article
MeSH Terms:: Autoimmunity*
Autoantibodies/*blood
Cytokines/*blood
Epidermolysis Bullosa/*pathology
Adolescent ; Adult ; Case-Control Studies ; Child ; Child, Preschool ; Collagen Type VII/immunology ; Desmoglein 1/immunology ; Desmoglein 3/immunology ; Epidermolysis Bullosa/metabolism ; Female ; Humans ; Male ; Severity of Illness Index ; Young Adult

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Skocz do pozycji: 5.

Tytuł:: Autoantibody Profile of a Cohort of 78 Italian Patients with Mucous Membrane Pemphigoid: Correlation Between Reactivity Profile and Clinical Involvement.
Autorzy:: Cozzani E; Department of Dermatology, IRCCS AOU san martino-IST, DISSAL, Sezione di Dermatologia , University of Genoa, IT-16100 Genova, Italy. .
Di Zenzo G
Calabresi V
Carrozzo M
Burlando M
Longanesi L
Cerri A
Caproni M
Sera F
Antiga E
Quaglino P
Marzano AV
Parodi A; Pokaż więcej
Źródło:: Acta dermato-venereologica [Acta Derm Venereol] 2016 Aug 23; Vol. 96 (6), pp. 768-73.
Typ publikacji:: Journal Article; Multicenter Study
MeSH Terms:: Autoantibodies/*blood
Pemphigoid, Benign Mucous Membrane/*immunology
Aged ; Collagen Type VII/immunology ; Electrophoresis, Polyacrylamide Gel ; Enzyme-Linked Immunosorbent Assay ; Female ; Fluorescent Antibody Technique, Indirect ; Humans ; Immunity, Humoral ; Immunoblotting ; Italy ; Male ; Non-Fibrillar Collagens/immunology ; Retrospective Studies ; Severity of Illness Index

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Skocz do pozycji: 6.

Tytuł:: Prevalence of collagen VII-specific autoantibodies in patients with autoimmune and inflammatory diseases.
Autorzy:: Licarete E; Department of Dermatology, University of Freiburg, Hauptstr, 7, Freiburg 79104, Germany.
Ganz S
Recknagel MJ
Di Zenzo G
Hashimoto T
Hertl M
Zambruno G
Hundorfean G
Mudter J
Neurath MF
Bruckner-Tuderman L
Sitaru C; Pokaż więcej
Źródło:: BMC immunology [BMC Immunol] 2012 Apr 04; Vol. 13, pp. 16. Date of Electronic Publication: 2012 Apr 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Enzyme-Linked Immunosorbent Assay*
Autoantibodies/*blood
Autoimmune Diseases/*blood
Collagen Type VII/*immunology
Inflammation/*blood
Autoimmune Diseases/immunology ; C-Reactive Protein/metabolism ; Cells, Cultured ; Collagen Type VII/genetics ; Epitope Mapping ; Epitopes/genetics ; Epitopes/immunology ; Humans ; Immunoglobulin G/blood ; Inflammation/immunology ; Inflammation Mediators/metabolism ; Protein Engineering ; Protein Structure, Tertiary/genetics ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/immunology

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Skocz do pozycji: 7.

Tytuł:: Heat shock protein 90 is required for ex vivo neutrophil-driven autoantibody-induced tissue damage in experimental epidermolysis bullosa acquisita.
Autorzy:: Tukaj S; Department of Dermatology, University of Lübeck, Lübeck, Germany.
Hellberg L; Institute of Medical Microbiology and Hygiene, University of Lübeck, Lübeck, Germany.
Ueck C; Institute of Medical Microbiology and Hygiene, University of Lübeck, Lübeck, Germany.
Hänsel M; Department of Dermatology, University of Lübeck, Lübeck, Germany.
Samavedam U; Department of Dermatology, University of Lübeck, Lübeck, Germany.
Zillikens D; Department of Dermatology, University of Lübeck, Lübeck, Germany.
Ludwig RJ; Department of Dermatology, University of Lübeck, Lübeck, Germany.
Laskay T; Institute of Medical Microbiology and Hygiene, University of Lübeck, Lübeck, Germany.
Kasperkiewicz M; Department of Dermatology, University of Lübeck, Lübeck, Germany.; Pokaż więcej
Źródło:: Experimental dermatology [Exp Dermatol] 2015 Jun; Vol. 24 (6), pp. 471-3. Date of Electronic Publication: 2015 Mar 25.
Typ publikacji:: Letter; Research Support, Non-U.S. Gov't
MeSH Terms:: Autoantibodies/*physiology
Epidermolysis Bullosa Acquisita/*pathology
Epidermolysis Bullosa Acquisita/*physiopathology
HSP90 Heat-Shock Proteins/*physiology
Neutrophils/*pathology
Skin/*pathology
Autoantibodies/immunology ; Benzoquinones/pharmacology ; Case-Control Studies ; Cells, Cultured ; Collagen Type VII/immunology ; Dose-Response Relationship, Drug ; Epidermolysis Bullosa Acquisita/immunology ; HSP90 Heat-Shock Proteins/antagonists & inhibitors ; HSP90 Heat-Shock Proteins/drug effects ; Humans ; Immunoprecipitation ; Lactams, Macrocyclic/pharmacology ; Matrix Metalloproteinase 12/physiology ; Matrix Metalloproteinase 2/physiology ; Neutrophils/drug effects ; Neutrophils/metabolism ; Reactive Oxygen Species/metabolism ; Skin/drug effects ; Skin/physiopathology

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Skocz do pozycji: 8.

Tytuł:: Autoimmunity to type VII collagen in SKH1 mice is independent of regulatory T cells.
Autorzy:: Chen L; Department of Dermatology, University of Illinois-Chicago, 808 S. Wood Street, Chicago, IL 60612, USA.
Peterson JD
Zheng WY
Lin SX
Chan LS; Pokaż więcej
Źródło:: Clinical and experimental immunology [Clin Exp Immunol] 2006 Aug; Vol. 145 (2), pp. 322-31.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Autoantibodies/*analysis
Collagen Type VII/*immunology
Epidermolysis Bullosa Acquisita/*immunology
T-Lymphocytes, Regulatory/*immunology
Animals ; Autoantibodies/genetics ; Basement Membrane/immunology ; Blotting, Western/methods ; Cloning, Molecular ; Collagen Type VII/genetics ; Enzyme-Linked Immunosorbent Assay/methods ; Female ; Immunoglobulin G/analysis ; Immunoglobulin kappa-Chains/analysis ; Mice ; Mice, Inbred Strains ; Microscopy, Fluorescence/methods ; Models, Animal ; Rats ; Rats, Sprague-Dawley ; Recombinant Proteins/genetics ; Recombinant Proteins/immunology ; Time Factors

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Skocz do pozycji: 9.

Tytuł:: Persistent autoantibody-production by intermediates between short-and long-lived plasma cells in inflamed lymph nodes of experimental epidermolysis bullosa acquisita.
Autorzy:: Tiburzy B; Institute for Systemic Inflammation Research (ISEF), University of Lübeck, Lübeck, Germany.
Szyska M; Institute for Systemic Inflammation Research (ISEF), University of Lübeck, Lübeck, Germany.
Iwata H; Department of Dermatology, University of Lübeck, Lübeck, Germany.
Chrobok N; Institute of Anatomy, University of Lübeck, Lübeck, Germany.
Kulkarni U; Institute for Systemic Inflammation Research (ISEF), University of Lübeck, Lübeck, Germany.
Hirose M; Department of Dermatology, University of Lübeck, Lübeck, Germany.
Ludwig RJ; Department of Dermatology, University of Lübeck, Lübeck, Germany.
Kalies K; Institute of Anatomy, University of Lübeck, Lübeck, Germany.
Westermann J; Institute of Anatomy, University of Lübeck, Lübeck, Germany.
Wong D; Institute for Systemic Inflammation Research (ISEF), University of Lübeck, Lübeck, Germany.
Manz RA; Institute for Systemic Inflammation Research (ISEF), University of Lübeck, Lübeck, Germany.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Dec 26; Vol. 8 (12), pp. e83631. Date of Electronic Publication: 2013 Dec 26 (Print Publication: 2013).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Autoantibodies/*immunology
Epidermolysis Bullosa Acquisita/*immunology
Lymph Nodes/*immunology
Plasma Cells/*immunology
Animals ; Autoantibodies/biosynthesis ; Autoantibodies/blood ; Bone Marrow/immunology ; Bone Marrow/metabolism ; Collagen Type VII/immunology ; Disease Models, Animal ; Epidermolysis Bullosa Acquisita/blood ; Epidermolysis Bullosa Acquisita/metabolism ; Epitopes, B-Lymphocyte/immunology ; Lymph Nodes/metabolism ; Mice ; Plasma Cells/metabolism ; Spleen/immunology ; Spleen/metabolism ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism