HIV envelope antigen valency on peptide nanofibers modulates antibody magnitude and binding breadth.
Autorzy:
Fries CN; Department of Biomedical Engineering, Duke University, 101 Science Dr., Campus, Box 90281, Durham, NC, 27708, USA. Chen JL; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. Dennis ML; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. Votaw NL; Department of Biomedical Engineering, Duke University, 101 Science Dr., Campus, Box 90281, Durham, NC, 27708, USA. Eudailey J; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. Watts BE; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. Hainline KM; Department of Biomedical Engineering, Duke University, 101 Science Dr., Campus, Box 90281, Durham, NC, 27708, USA. Cain DW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. Barfield R; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, 27710, USA. Chan C; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, 27710, USA. Moody MA; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pediatrics, Duke University Medical Center, Duke University School of Medicine, Box 103020, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA. Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA. Saunders KO; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA. Permar SR; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pediatrics, Duke University Medical Center, Duke University School of Medicine, Box 103020, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pediatrics, New York-Presbyterian/Weill Cornell Medicine, New York, NY, 10065, USA. Fouda GG; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA. .; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. .; Department of Pediatrics, Duke University Medical Center, Duke University School of Medicine, Box 103020, Durham, NC, 27710, USA. . CollierJH; Department of Biomedical Engineering, Duke University, 101 Science Dr., Campus, Box 90281, Durham, NC, 27708, USA. joel.collier@duke.edu.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA. joel.collier@duke.edu.
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Źródło:
Scientific reports [Sci Rep] 2021 Jul 14; Vol. 11 (1), pp. 14494. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Gradated assembly of multiple proteins into supramolecular nanomaterials.
Autorzy:
Hudalla GA; 1] Department of Surgery, University of Chicago, 5841 S. Maryland Avenue ML 5032 Chicago, Illinois 60637, USA [2]. Sun T; Department of Surgery, University of Chicago, 5841 S. Maryland Avenue ML 5032 Chicago, Illinois 60637, USA. Gasiorowski JZ; Department of Surgery, University of Chicago, 5841 S. Maryland Avenue ML 5032 Chicago, Illinois 60637, USA. Han H; Department of Surgery, University of Chicago, 5841 S. Maryland Avenue ML 5032 Chicago, Illinois 60637, USA. Tian YF; 1] Department of Surgery, University of Chicago, 5841 S. Maryland Avenue ML 5032 Chicago, Illinois 60637, USA [2] Illinois Institute of Technology, Department of Biomedical Engineering, 3300 S. Federal Street Chicago, Illinois 60616, USA. Chong AS; 1] Department of Surgery, University of Chicago, 5841 S. Maryland Avenue ML 5032 Chicago, Illinois 60637, USA [2] Committee on Immunology, University of Chicago, 5841 S. Maryland Avenue ML 5032 Chicago, Illinois 60637, USA. CollierJH; 1] Department of Surgery, University of Chicago, 5841 S. Maryland Avenue ML 5032 Chicago, Illinois 60637, USA [2] Committee on Immunology, University of Chicago, 5841 S. Maryland Avenue ML 5032 Chicago, Illinois 60637, USA [3] Committee on Molecular Medicine, University of Chicago, 5841 S. Maryland Avenue ML 5032 Chicago, Illinois 60637, USA.
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Źródło:
Nature materials [Nat Mater] 2014 Aug; Vol. 13 (8), pp. 829-36. Date of Electronic Publication: 2014 Jun 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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