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Wyszukujesz frazę ""Colorectal Neoplasms"" wg kryterium: Temat


Tytuł:
Activin and Hepatocyte Growth Factor Promotes Colorectal Cancer Stemness and Metastasis through FOXM1/SOX2/CXCR4 Signaling.
Autorzy:
Peng H; Department of Gastroenterology and Hepatology, Bishan Hospital of Chongqing, Bishan Hospital of Chongqing Medical University, Chongqing, China.
Ye T; Department of Gastroenterology and Hepatology, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing University School of Medicine, Chongqing, China.
Deng L; Department of Gastroenterology and Hepatology, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing University School of Medicine, Chongqing, China.
Yang X; Department of Gastroenterology and Hepatology, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing University School of Medicine, Chongqing, China.
Li Q; Institute of Life Sciences, Chongqing Medical University, Chongqing, China.
Tong J; Department of Gastroenterology and Hepatology, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing University School of Medicine, Chongqing, China.
Guo J; Department of Gastroenterology and Hepatology, Bishan Hospital of Chongqing, Bishan Hospital of Chongqing Medical University, Chongqing, China.
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Źródło:
Gut and liver [Gut Liver] 2024 May 15; Vol. 18 (3), pp. 476-488. Date of Electronic Publication: 2023 Jul 17.
Typ publikacji:
Journal Article
MeSH Terms:
Hepatocyte Growth Factor*/pharmacology
Hepatocyte Growth Factor*/metabolism
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/metabolism
Activins*/metabolism
SOXB1 Transcription Factors*/metabolism
SOXB1 Transcription Factors*/genetics
Forkhead Box Protein M1*/metabolism
Forkhead Box Protein M1*/genetics
Neoplastic Stem Cells*/drug effects
Neoplastic Stem Cells*/metabolism
Neoplastic Stem Cells*/pathology
Signal Transduction*/drug effects
Humans ; Cell Line, Tumor ; Receptors, CXCR4/metabolism ; Receptors, CXCR4/genetics ; Neoplasm Metastasis ; Carcinogenesis/drug effects ; Carcinogenesis/genetics ; Animals
Czasopismo naukowe
Tytuł:
Tumor analysis of MMR genes in Lynch-like syndrome: Challenges associated with results interpretation.
Autorzy:
Rofes P; Hereditary Cancer Program, Catalan Institute of Oncology, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Dueñas N; Hereditary Cancer Program, Catalan Institute of Oncology, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Del Valle J; Hereditary Cancer Program, Catalan Institute of Oncology, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Navarro M; Hereditary Cancer Program, Catalan Institute of Oncology, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.
Balmaña J; Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Hospital, Barcelona, Spain.
Ramón Y Cajal T; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Tuset N; Medical Oncology Department, Arnau de Vilanova University Hospital, Lleida, Spain.
Castillo C; Hereditary Cancer Program, Catalan Institute of Oncology, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.
González S; Hereditary Cancer Program, Catalan Institute of Oncology, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Brunet J; Hereditary Cancer Program, Catalan Institute of Oncology, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hereditary Cancer Program, Catalan Institute of Oncology - IDIBGi, Girona, Spain.
Capellá G; Hereditary Cancer Program, Catalan Institute of Oncology, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Lázaro C; Hereditary Cancer Program, Catalan Institute of Oncology, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Pineda M; Hereditary Cancer Program, Catalan Institute of Oncology, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
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Źródło:
Cancer medicine [Cancer Med] 2024 Apr; Vol. 13 (7), pp. e7041.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms, Hereditary Nonpolyposis*/diagnosis
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
Colorectal Neoplasms, Hereditary Nonpolyposis*/pathology
Neoplastic Syndromes, Hereditary*
Brain Neoplasms*
Humans ; Germ-Line Mutation ; DNA Mismatch Repair/genetics
Czasopismo naukowe
Tytuł:
A Phase 1b/2a Study of GC1118 with 5-Fluorouracil, Leucovorin and Irinotecan (FOLFIRI) in Patients with Recurrent or Metastatic Colorectal Cancer.
Autorzy:
Lee KW; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Han SW; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.; Seoul National University Cancer Research Institute, Seoul, Korea.
Kim TW; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Ahn JB; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.
Baek JY; Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Cho SH; Division of Hemato-Oncology, Department of Internal Medicine, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea.
Lee H; Department of Clinical Pharmacology and Therapeutics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea.
Kim JW; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Kim JW; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Kim TY; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.; Seoul National University Cancer Research Institute, Seoul, Korea.
Hong YS; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Beom SH; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.
Cha Y; Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Choi Y; GC Biopharma Corp., Yongin, Korea.
Kim S; GC Biopharma Corp., Yongin, Korea.
Bang YJ; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
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Źródło:
Cancer research and treatment [Cancer Res Treat] 2024 Apr; Vol. 56 (2), pp. 590-601. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Clinical Trial, Phase I; Journal Article
MeSH Terms:
Colonic Neoplasms*/drug therapy
Rectal Neoplasms*/drug therapy
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Antibodies, Monoclonal, Humanized*
Humans ; Irinotecan/therapeutic use ; Fluorouracil/adverse effects ; Leucovorin/adverse effects ; Camptothecin/adverse effects ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/etiology ; ErbB Receptors ; Antineoplastic Combined Chemotherapy Protocols/adverse effects
Czasopismo naukowe
Tytuł:
RAS/RAF mutations and microsatellite instability status in primary colorectal cancers according to HER2 amplification.
Autorzy:
Lee SM; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, 350 W. 11th Street, Indianapolis, IN, 46202, USA. .; Department of Pathology, Jeju National University Hospital, Jeju-si, South Korea. .
Oh H; Department of Internal Medicine, Jeju National University Hospital, Jeju-si, South Korea.
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Źródło:
Scientific reports [Sci Rep] 2024 May 19; Vol. 14 (1), pp. 11432. Date of Electronic Publication: 2024 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Receptor, ErbB-2*/genetics
Receptor, ErbB-2*/metabolism
Mutation*
Gene Amplification*
Humans ; Female ; Male ; Middle Aged ; Aged ; Adult ; Aged, 80 and over ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins p21(ras)/genetics ; High-Throughput Nucleotide Sequencing ; ras Proteins/genetics
Czasopismo naukowe
Tytuł:
Squalene epoxidase promotes the chemoresistance of colorectal cancer via (S)-2,3-epoxysqualene-activated NF-κB.
Autorzy:
Liu Q; Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Zhang Y; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Li H; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China.
Gao H; State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Zhou Y; State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Luo D; Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Shan Z; Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Yang Y; Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Weng J; Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Li Q; Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Yang W; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China. .; State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. .
Li X; Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China. .; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 May 18; Vol. 22 (1), pp. 278. Date of Electronic Publication: 2024 May 18.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/metabolism
Squalene Monooxygenase*/metabolism
Squalene Monooxygenase*/genetics
NF-kappa B*/metabolism
Drug Resistance, Neoplasm*/genetics
Drug Resistance, Neoplasm*/drug effects
Fluorouracil*/pharmacology
Fluorouracil*/therapeutic use
Humans ; Animals ; Mice ; Cell Line, Tumor ; Mice, Nude ; Mice, Inbred BALB C ; Female ; Male ; Cell Proliferation/drug effects ; NF-KappaB Inhibitor alpha/metabolism ; NF-KappaB Inhibitor alpha/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Long non-coding RNA RP11-197K6.1 as ceRNA promotes colorectal cancer progression via miR-135a-5p/DLX5 axis.
Autorzy:
Wang M; The Fifth School of Clinical Medicine, Navy Clinical College, Anhui Medical University, Hefei, Anhui, 230032, China.; Department of General Surgery, The First Medical Center, Chinese PLA General Hospital, 28 Fuxing road, Haidian District, Beijing, 100853, China.; Department of General Surgery, The Sixth Medical Center of PLA General Hospital, 6 Fucheng road, Haidian District, Beijing, 100048, China.
Niu X; Department of General Surgery, School of Medicine, South China University of Technology, Guangzhou, 510006, China.; Department of General Surgery, The First Medical Center, Chinese PLA General Hospital, 28 Fuxing road, Haidian District, Beijing, 100853, China.; Department of General Surgery, The Sixth Medical Center of PLA General Hospital, 6 Fucheng road, Haidian District, Beijing, 100048, China.
Wang M; Department of General Surgery, The First Medical Center, Chinese PLA General Hospital, 28 Fuxing road, Haidian District, Beijing, 100853, China.
Zheng P; The Fifth School of Clinical Medicine, Navy Clinical College, Anhui Medical University, Hefei, Anhui, 230032, China.; Department of General Surgery, The First Medical Center, Chinese PLA General Hospital, 28 Fuxing road, Haidian District, Beijing, 100853, China.; Department of General Surgery, The Sixth Medical Center of PLA General Hospital, 6 Fucheng road, Haidian District, Beijing, 100048, China.
Liu X; Department of General Surgery, School of Medicine, South China University of Technology, Guangzhou, 510006, China.; Department of General Surgery, The First Medical Center, Chinese PLA General Hospital, 28 Fuxing road, Haidian District, Beijing, 100853, China.; Department of General Surgery, The Sixth Medical Center of PLA General Hospital, 6 Fucheng road, Haidian District, Beijing, 100048, China.
Cao Z; The Fifth School of Clinical Medicine, Navy Clinical College, Anhui Medical University, Hefei, Anhui, 230032, China. .; Department of General Surgery, School of Medicine, South China University of Technology, Guangzhou, 510006, China. .; Department of General Surgery, The First Medical Center, Chinese PLA General Hospital, 28 Fuxing road, Haidian District, Beijing, 100853, China. .; Department of General Surgery, The Sixth Medical Center of PLA General Hospital, 6 Fucheng road, Haidian District, Beijing, 100048, China. .
Zhang C; The Fifth School of Clinical Medicine, Navy Clinical College, Anhui Medical University, Hefei, Anhui, 230032, China. .; Department of General Surgery, School of Medicine, South China University of Technology, Guangzhou, 510006, China. .; Department of General Surgery, The First Medical Center, Chinese PLA General Hospital, 28 Fuxing road, Haidian District, Beijing, 100853, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 May 17; Vol. 22 (1), pp. 469. Date of Electronic Publication: 2024 May 17.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/metabolism
Disease Progression*
Homeodomain Proteins*/genetics
Homeodomain Proteins*/metabolism
Gene Expression Regulation, Neoplastic*
Cell Movement*/genetics
Mice, Nude*
Humans ; Animals ; Cell Line, Tumor ; Male ; Female ; Apoptosis/genetics ; Cell Proliferation/genetics ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Base Sequence ; Mice, Inbred BALB C ; Middle Aged ; Mice ; RNA, Competitive Endogenous
Czasopismo naukowe
Tytuł:
Understanding the interplay of colorectal cancer awareness and attitudes among Palestinians: a national cross-sectional study.
Autorzy:
Elshami M; Division of Surgical Oncology, Department of Surgery, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Lakeside, Cleveland, OH, 7100, 44106, USA. .; Ministry of Health, Gaza, Palestine. .
Dwikat MF; Department of Internships, An-Najah National University Hospital, Nablus, Palestine.
Al-Slaibi I; Almakassed Hospital, Jerusalem, Palestine.
Alser M; The United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA), Gaza, Palestine.
Albandak ME; Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Ayyad M; Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Naji SA; Faculty of Pharmacy, Al-Azhar University of Gaza, Gaza, Palestine.
Mohamad BM; Doctors Without Borders (Médecins Sans Frontières), Hebron, Palestine.
Isleem WS; Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.
Shurrab A; Nasser Medical Complex, Khanyounis, Palestine.
Yaghi B; Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Qabaja YA; Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Hamdan FK; Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Sweity RR; Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Jneed RT; Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.
Assaf KA; Faculty of Medicine, An-Najah National University, Nablus, Palestine.
Hmaid MM; Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.
Awwad II; Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Alhabil BK; Ministry of Health, Gaza, Palestine.
Alarda MN; Faculty of Dentistry, Arab American University, Jenin, Palestine.
Alsattari AS; Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.
Aboyousef MS; Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.
Aljbour OA; Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.
AlSharif R; Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Giacaman CT; Augusta Victoria Hospital, Jerusalem, Palestine.
Alnaga AY; Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.
Nemer RMA; Faculty of Allied Medical Sciences, Arab American University, Jenin, Palestine.
Almadhoun NM; Faculty of Medicine, Al-Azhar University, Gaza, Palestine.
Skaik SM; Faculty of Medicine, Al-Azhar University, Gaza, Palestine.
Albarqi SI; Faculty of Pharmacy, Al-Azhar University of Gaza, Gaza, Palestine.
Abu-El-Noor N; Faculty of Nursing, Islamic University of Gaza, Gaza, Palestine.
Bottcher B; Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.
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Źródło:
BMC cancer [BMC Cancer] 2024 May 15; Vol. 24 (1), pp. 590. Date of Electronic Publication: 2024 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/psychology
Colorectal Neoplasms*/epidemiology
Health Knowledge, Attitudes, Practice*
Arabs*/psychology
Humans ; Cross-Sectional Studies ; Female ; Male ; Middle Aged ; Adult ; Risk Factors ; Aged ; Surveys and Questionnaires ; Young Adult ; Middle East/epidemiology
Czasopismo naukowe
Tytuł:
Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance).
Autorzy:
Quintanilha JCF; UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Sibley AB; Duke Cancer Institute, Duke University Medical Center, Durham, NC, USA.
Liu Y; Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Niedzwiecki D; Duke Cancer Institute, Duke University Medical Center, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.; Alliance Statistics and Data Management Center, Duke University, Durham, NC, USA.
Halabi S; Duke Cancer Institute, Duke University Medical Center, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.; Alliance Statistics and Data Management Center, Duke University, Durham, NC, USA.
Rogers L; Duke Cancer Institute, Duke University Medical Center, Durham, NC, USA.
O'Neil B; Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA.
Kindler H; Department of Medicine, The University of Chicago, Chicago, IL, USA.
Kelly W; Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.
Venook A; Department of Medicine, University of California at San Francisco, San Francisco, CA, USA.
McLeod HL; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Utah Tech University, St George, UT, USA.
Ratain MJ; Department of Medicine, The University of Chicago, Chicago, IL, USA.
Nixon AB; Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Innocenti F; Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Owzar K; Duke Cancer Institute, Duke University Medical Center, Durham, NC, USA. .; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA. .; Alliance Statistics and Data Management Center, Duke University, Durham, NC, USA. .
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Źródło:
BMC genomics [BMC Genomics] 2024 May 14; Vol. 25 (1), pp. 473. Date of Electronic Publication: 2024 May 14.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/blood
Colorectal Neoplasms*/pathology
Transforming Growth Factor beta2*/genetics
Transforming Growth Factor beta2*/blood
RNA, Long Noncoding*/blood
RNA, Long Noncoding*/genetics
Humans ; Male ; Female ; Quantitative Trait Loci ; Middle Aged ; Neoplasm Metastasis ; Aged ; Polymorphism, Single Nucleotide ; Biomarkers, Tumor/blood ; Biomarkers, Tumor/genetics ; Genome-Wide Association Study
Czasopismo naukowe
Tytuł:
Estimating effects of whole grain consumption on type 2 diabetes, colorectal cancer and cardiovascular disease: a burden of proof study.
Autorzy:
Liu H; Department of Epidemiology and Health Statistics, School of Public Health, Hangzhou Medical College, 481 Binwen Road, Hangzhou, 310053, China.
Zhu J; Department of Epidemiology and Health Statistics, School of Public Health, Hangzhou Medical College, 481 Binwen Road, Hangzhou, 310053, China.
Gao R; Department of Epidemiology and Health Statistics, School of Public Health, Hangzhou Medical College, 481 Binwen Road, Hangzhou, 310053, China.
Ding L; Department of Epidemiology and Health Statistics, School of Public Health, Hangzhou Medical College, 481 Binwen Road, Hangzhou, 310053, China.
Yang Y; Department of Epidemiology and Health Statistics, School of Public Health, Hangzhou Medical College, 481 Binwen Road, Hangzhou, 310053, China.
Zhao W; Department of Epidemiology and Health Statistics, School of Public Health, Hangzhou Medical College, 481 Binwen Road, Hangzhou, 310053, China.
Cui X; Department of Radiology, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Lu W; Department of Epidemiology and Health Statistics, School of Public health, Tianjin Medical University, Tianjin, China.
Wang J; Department of Epidemiology and Health Statistics, School of Public Health, Hangzhou Medical College, 481 Binwen Road, Hangzhou, 310053, China. .
Li Y; Department of Epidemiology and Health Statistics, School of Public Health, Hangzhou Medical College, 481 Binwen Road, Hangzhou, 310053, China. .
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Źródło:
Nutrition journal [Nutr J] 2024 May 14; Vol. 23 (1), pp. 49. Date of Electronic Publication: 2024 May 14.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/epidemiology
Colorectal Neoplasms*/epidemiology
Whole Grains*
Cardiovascular Diseases*/epidemiology
Cardiovascular Diseases*/prevention & control
Humans ; Diet/methods ; Diet/statistics & numerical data ; Prospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł:
The multifaceted role of extracellular vesicles (EVs) in colorectal cancer: metastasis, immune suppression, therapy resistance, and autophagy crosstalk.
Autorzy:
Rahmati S; Student Research Committee, Ramsar Campus, Mazandaran University of Medical Sciences, Ramsar, Iran.; Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Moeinafshar A; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Rezaei N; Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Dr. Qarib St, Keshavarz Blvd, Tehran, 14194, Iran. rezaei_.; Network of Immunity in Infection, Malignancy, and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran. rezaei_.; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. rezaei_.
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Źródło:
Journal of translational medicine [J Transl Med] 2024 May 13; Vol. 22 (1), pp. 452. Date of Electronic Publication: 2024 May 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/metabolism
Colorectal Neoplasms*/immunology
Autophagy*
Extracellular Vesicles*/metabolism
Neoplasm Metastasis*
Drug Resistance, Neoplasm*
Humans ; Animals ; Immunosuppression Therapy
Czasopismo naukowe
Tytuł:
Cell type specific long non-coding RNA targets identified by integrative analysis of single-cell and bulk colorectal cancer transcriptomes.
Autorzy:
Mihaljevic A; Department for BioMedical Research, University of Bern, 3008, Bern, Switzerland.; Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland.
Rubin PD; Department for BioMedical Research, University of Bern, 3008, Bern, Switzerland.; Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland.
Chouvardas P; Urology Research Laboratory, Department for BioMedical Research, University of Bern, 3008, Bern, Switzerland. .; Department of Urology, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland. .
Esposito R; Department for BioMedical Research, University of Bern, 3008, Bern, Switzerland. .; Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland. .; Institute of Genetics and Biophysics Adriano Buzzati-Traverso (IGB-ABT), National Research Council (CNR), Naples, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2024 May 13; Vol. 14 (1), pp. 10939. Date of Electronic Publication: 2024 May 13.
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Long Noncoding*/genetics
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Gene Expression Regulation, Neoplastic*
Transcriptome*
Humans ; Single-Cell Analysis/methods ; Cell Line, Tumor ; Gene Expression Profiling ; Cell Proliferation/genetics
Czasopismo naukowe
Tytuł:
Cetuximab plus FOLFOXIRI versus cetuximab plus FOLFOX as conversion regimen in RAS/BRAF wild-type patients with initially unresectable colorectal liver metastases (TRICE trial): A randomized controlled trial.
Autorzy:
Wang DS; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Ren C; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Li SS; Department of Internal Medicine, The 6th Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Fong WP; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Wu XJ; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Xiao J; Department of Internal Medicine, The 6th Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.; Department of Medical Oncology, Guangdong Provincial People's Hospital, Southern Medical University, Guangzhou, China.
Li BK; Department of Liver Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zheng Y; Department of Liver Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Ding PR; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Chen G; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Qiu MZ; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Wang ZQ; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Wang FH; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Luo HY; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Wang F; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Wang XZ; Shantou Central Hospital, Shantou, China.
Wang LY; Department of Internal Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Xie DJ; Shantou Central Hospital, Shantou, China.
Chen T; Department of Internal Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Li LR; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Lu ZH; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zhai XH; Department of Internal Medicine, The 6th Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Liu TS; Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, China.
Yuan Y; Department of Medical Oncology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chen JQ; Department of Medical Oncology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Tan Q; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Pan ZZ; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Wan DS; Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zhang R; Department of Medical Imaging, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Yuan YF; Department of Liver Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Xu RH; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.; Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, China.
Li YH; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
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Źródło:
PLoS medicine [PLoS Med] 2024 May 10; Vol. 21 (5), pp. e1004389. Date of Electronic Publication: 2024 May 10 (Print Publication: 2024).
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Multicenter Study; Comparative Study
MeSH Terms:
Cetuximab*/administration & dosage
Cetuximab*/therapeutic use
Antineoplastic Combined Chemotherapy Protocols*/therapeutic use
Liver Neoplasms*/secondary
Liver Neoplasms*/drug therapy
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/pathology
Leucovorin*/therapeutic use
Leucovorin*/administration & dosage
Fluorouracil*/therapeutic use
Fluorouracil*/administration & dosage
Organoplatinum Compounds*/therapeutic use
Organoplatinum Compounds*/administration & dosage
Proto-Oncogene Proteins B-raf*/genetics
Camptothecin*/analogs & derivatives
Camptothecin*/therapeutic use
Camptothecin*/administration & dosage
Humans ; Male ; Middle Aged ; Female ; Aged ; Adult ; Treatment Outcome ; ras Proteins/genetics
SCR Protocol:
FOLFOXIRI protocol; Folfox protocol
Czasopismo naukowe
Tytuł:
Establishment and validation of an artificial intelligence-based model for real-time detection and classification of colorectal adenoma.
Autorzy:
Zhao L; Digestive Disease Center, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23, Back Street of Art Museum, Dongcheng District, Beijing, 100010, China.
Wang N; School of Mathematics and Statistics, Beijing Institute of Technology, No. 5, South Street, Zhongguancun, Haidian District, Beijing, 100081, China.
Zhu X; Digestive Disease Center, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23, Back Street of Art Museum, Dongcheng District, Beijing, 100010, China.
Wu Z; Digestive Disease Center, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23, Back Street of Art Museum, Dongcheng District, Beijing, 100010, China.
Shen A; Digestive Disease Center, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23, Back Street of Art Museum, Dongcheng District, Beijing, 100010, China.
Zhang L; Shunyi Hospital, Beijing Traditional Chinese Medicine Hospital, Beijing, China.
Wang R; Digestive Disease Center, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23, Back Street of Art Museum, Dongcheng District, Beijing, 100010, China.
Wang D; School of Mathematics and Statistics, Beijing Institute of Technology, No. 5, South Street, Zhongguancun, Haidian District, Beijing, 100081, China. .
Zhang S; Digestive Disease Center, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23, Back Street of Art Museum, Dongcheng District, Beijing, 100010, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 May 10; Vol. 14 (1), pp. 10750. Date of Electronic Publication: 2024 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:
Colorectal Neoplasms*/diagnosis
Colorectal Neoplasms*/classification
Adenoma*/diagnosis
Adenoma*/classification
Artificial Intelligence*
Humans ; Colonoscopy/methods ; Early Detection of Cancer/methods ; Colonic Polyps/diagnosis ; Colonic Polyps/classification ; Colonic Polyps/pathology ; Algorithms
Czasopismo naukowe
Tytuł:
Identification of DNA methylation characteristics associated with metastasis and prognosis in colorectal cancer.
Autorzy:
Qian F; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.; Guoke Ningbo Life Science and Health Industry Research Institute, Ningbo, 315000, China.
Li Q; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Chang H; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Wei K; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Chen X; Guoke Ningbo Life Science and Health Industry Research Institute, Ningbo, 315000, China. .
Huang T; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China. .
Li Y; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China. .; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China. .; Guangzhou Laboratory, Guangzhou, 510005, China. .; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China. .; Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, 200433, China. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2024 May 10; Vol. 17 (1), pp. 127. Date of Electronic Publication: 2024 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
DNA Methylation*
Neoplasm Metastasis*
Humans ; Prognosis ; Biomarkers, Tumor/genetics ; CpG Islands/genetics ; Tumor Microenvironment ; Female ; Male ; Gene Expression Regulation, Neoplastic ; Nomograms
Czasopismo naukowe
Tytuł:
Investigation of ENO2 as a promising novel marker for the progression of colorectal cancer with microsatellite instability-high.
Autorzy:
Cai J; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325000, China.; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China.
Yang Y; Department of Clinical Laboratory, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, China.; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China.
Zhang L; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325000, China.; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China.
Fang Y; Department of Clinical Laboratory, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, China.; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China.
Zhang Y; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325000, China.; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China.
Tan M; Department of Clinical Laboratory, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Zhang J; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325000, China.
Tang C; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325000, China.; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China.
Ren H; Department of Clinical Laboratory, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, China.; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China.
Wang L; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325000, China.; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China.
Xiang G; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325000, China.; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China.
Xu F; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325000, China.; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China.
Lan L; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Li L; General Surgery Department, Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Zheng X; Department of Clinical Laboratory, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, China. .; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325000, China. .; The Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou, 325035, China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 May 09; Vol. 24 (1), pp. 573. Date of Electronic Publication: 2024 May 09.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/mortality
Colorectal Neoplasms*/metabolism
Microsatellite Instability*
Biomarkers, Tumor*/genetics
Biomarkers, Tumor*/metabolism
Phosphopyruvate Hydratase*/genetics
Phosphopyruvate Hydratase*/metabolism
Disease Progression*
Humans ; Prognosis ; Female ; Male ; Gene Expression Regulation, Neoplastic ; Epithelial-Mesenchymal Transition/genetics ; Middle Aged ; Nomograms ; Single-Cell Analysis ; DNA Copy Number Variations
Czasopismo naukowe
Tytuł:
Protein expression of the amino acid transporter SLC7A5 in tumor tissue is prognostic in early-stage colorectal cancer.
Autorzy:
Ogawa M; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Tanaka A; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Maekawa M; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Namba K; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Otani Y; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Shia J; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America.
Wang JY; Curandis, New York, NY, United States of America.
Roehrl MH; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
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Źródło:
PloS one [PLoS One] 2024 May 09; Vol. 19 (5), pp. e0298362. Date of Electronic Publication: 2024 May 09 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/metabolism
Large Neutral Amino Acid-Transporter 1*/metabolism
Large Neutral Amino Acid-Transporter 1*/genetics
Neoplasm Staging*
Humans ; Male ; Female ; Prognosis ; Middle Aged ; Aged ; Biomarkers, Tumor/metabolism ; Biomarkers, Tumor/genetics ; Gene Expression Regulation, Neoplastic ; Disease-Free Survival ; Immunohistochemistry ; Aged, 80 and over ; Fusion Regulatory Protein 1, Heavy Chain
Czasopismo naukowe
Tytuł:
Cetuximab inhibits colorectal cancer development through inactivating the Wnt/β-catenin pathway and modulating PLCB3 expression.
Autorzy:
Zhang X; Fengxian District Center Hospital Graduate Student Training Base, Jinzhou Medical University, No. 6600 Nanfeng Road, Shanghai, 201499, China.; Endoscopy Center, Minhang Hospital, Fudan University, No. 170 Xinsong Road, Shanghai, 201199, China.
Zhou W; Endoscopy Center, Minhang Hospital, Fudan University, No. 170 Xinsong Road, Shanghai, 201199, China.
Wu C; Endoscopy Center, Minhang Hospital, Fudan University, No. 170 Xinsong Road, Shanghai, 201199, China.
Jiang J; Endoscopy Center, Minhang Hospital, Fudan University, No. 170 Xinsong Road, Shanghai, 201199, China.
Guo Q; Fengxian District Center Hospital Graduate Student Training Base, Jinzhou Medical University, No. 6600 Nanfeng Road, Shanghai, 201499, China.
Feng L; Endoscopy Center, Minhang Hospital, Fudan University, No. 170 Xinsong Road, Shanghai, 201199, China. fengli_.
Cheng X; Endoscopy Center, Minhang Hospital, Fudan University, No. 170 Xinsong Road, Shanghai, 201199, China. chengxun_mh_.
Zhang X; Fengxian District Center Hospital Graduate Student Training Base, Jinzhou Medical University, No. 6600 Nanfeng Road, Shanghai, 201499, China. .; Department of Gastroenterology, Shanghai Jiaotong University Affiliated Sixth People Hospital South Campus, No. 6600 Nanfeng Road, Shanghai, 201499, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 May 09; Vol. 14 (1), pp. 10642. Date of Electronic Publication: 2024 May 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/metabolism
Colorectal Neoplasms*/pathology
Cetuximab*/pharmacology
Wnt Signaling Pathway*/drug effects
Gene Expression Regulation, Neoplastic*/drug effects
Cell Proliferation*/drug effects
beta Catenin*/metabolism
beta Catenin*/genetics
Humans ; Cell Line, Tumor ; Cell Movement/drug effects ; Prognosis ; Antineoplastic Agents, Immunological/pharmacology
Czasopismo naukowe
Tytuł:
Fusobacterium nucleatum infection modulates the transcriptome and epigenome of HCT116 colorectal cancer cells in an oxygen-dependent manner.
Autorzy:
Udayasuryan B; School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, VA, USA.
Zhou Z; Department of Chemical Engineering, Virginia Tech, Blacksburg, VA, USA.
Ahmad RN; School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, VA, USA.
Sobol P; School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, VA, USA.
Deng C; Department of Chemical Engineering, Virginia Tech, Blacksburg, VA, USA.
Nguyen TTD; Department of Biochemistry, Virginia Tech, Blacksburg, VA, USA.
Kodikalla S; School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, VA, USA.
Morrison R; School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, VA, USA.
Goswami I; School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, VA, USA.
Slade DJ; Department of Biochemistry, Virginia Tech, Blacksburg, VA, USA.
Verbridge SS; School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, VA, USA.
Lu C; Department of Chemical Engineering, Virginia Tech, Blacksburg, VA, USA. .
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Źródło:
Communications biology [Commun Biol] 2024 May 08; Vol. 7 (1), pp. 551. Date of Electronic Publication: 2024 May 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Fusobacterium nucleatum*/genetics
Fusobacterium nucleatum*/physiology
Fusobacterium nucleatum*/pathogenicity
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/microbiology
Colorectal Neoplasms*/metabolism
Colorectal Neoplasms*/pathology
Epigenome*
Transcriptome*
Fusobacterium Infections*/genetics
Fusobacterium Infections*/microbiology
Fusobacterium Infections*/metabolism
Oxygen*/metabolism
Humans ; HCT116 Cells ; Tumor Microenvironment/genetics ; Gene Expression Regulation, Neoplastic
Czasopismo naukowe
Tytuł:
Correlation of gasdermin B staining patterns with prognosis, progression, and immune response in colorectal cancer.
Autorzy:
Sun L; Department of Pathology and Pathophysiology, Department of Hepatobiliary and Pancreatic Surgery of the Second Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.; Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.
Wang J; Department of Pathology and Pathophysiology, Department of Hepatobiliary and Pancreatic Surgery of the Second Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.; Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.
Li Y; Department of Pathology and Pathophysiology, Department of Hepatobiliary and Pancreatic Surgery of the Second Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.; Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.
Kang Y; Department of Pathology and Pathophysiology, Department of Hepatobiliary and Pancreatic Surgery of the Second Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.; Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.
Jiang Y; Department of Statistics, School of Mathematical Sciences, Anhui University, Hefei, Anhui, P.R. China.
Zhang J; Department of Pathology and Pathophysiology, Department of Hepatobiliary and Pancreatic Surgery of the Second Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.; Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.
Qian S; Department of Pathology and Pathophysiology, Department of Hepatobiliary and Pancreatic Surgery of the Second Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.; Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China.
Xu F; Department of Pathology and Pathophysiology, Department of Hepatobiliary and Pancreatic Surgery of the Second Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China. .; Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, Zhejiang, 310058, P. R. China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 May 06; Vol. 24 (1), pp. 567. Date of Electronic Publication: 2024 May 06.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/immunology
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/metabolism
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/mortality
Tumor Microenvironment*/immunology
Disease Progression*
Gasdermins*
Humans ; Male ; Prognosis ; Female ; Middle Aged ; Aged ; Biomarkers, Tumor/metabolism ; Fluorouracil/therapeutic use ; Fluorouracil/pharmacology ; Neoplasm Proteins/metabolism ; Immunohistochemistry ; Adult ; Macrophages/immunology ; Macrophages/metabolism ; Macrophages/pathology ; Pyroptosis
Czasopismo naukowe
Tytuł:
The Usefulness of Vitamin K-Dependent Proteins in the Diagnosis of Colorectal Carcinoma.
Autorzy:
Perné MG; 4th Department-Internal Medicine, 4th Medical Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Sitar-Tăut AV; 4th Department-Internal Medicine, 4th Medical Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Orășan OH; 4th Department-Internal Medicine, 4th Medical Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Negrean V; 4th Department-Internal Medicine, 4th Medical Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Vlad CV; 4th Department-Internal Medicine, 4th Medical Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Alexescu TG; 4th Department-Internal Medicine, 4th Medical Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Milaciu MV; 4th Department-Internal Medicine, 4th Medical Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Ciumărnean L; 4th Department-Internal Medicine, 4th Medical Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Togănel RD; 6th Department-Surgery, 4th Surgery Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Petre GE; 6th Department-Surgery, 4th Surgery Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Șimon I; 6th Department-Surgery, 4th Surgery Discipline, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Republicii Street, Nr. 18, 400015 Cluj-Napoca, Romania.
Crăciun A; 2nd Department-Molecular Sciences, Discipline of Medical Biochemistry, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Pasteur Street, Nr. 6, 400349 Cluj-Napoca, Romania.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 May 03; Vol. 25 (9). Date of Electronic Publication: 2024 May 03.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/blood
Colorectal Neoplasms*/diagnosis
Colorectal Neoplasms*/pathology
Biomarkers, Tumor*/blood
Prothrombin*/metabolism
Calcium-Binding Proteins*/blood
Matrix Gla Protein*
Humans ; Male ; Female ; Middle Aged ; Aged ; Extracellular Matrix Proteins/blood ; Protein Precursors/blood ; Adult ; Liver Neoplasms/blood ; Liver Neoplasms/diagnosis ; Liver Neoplasms/secondary ; Vitamin K/blood ; ROC Curve ; CA-19-9 Antigen/blood ; Carcinoembryonic Antigen/blood ; Biomarkers
Czasopismo naukowe

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