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Wyszukujesz frazę ""Colorectal Neoplasms, Hereditary Nonpolyposis"" wg kryterium: Temat


Tytuł :
DNA mismatch repair proteins: scientific update and practical guide.
Autorzy :
Bateman AC; Cellular Pathology, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK .
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Źródło :
Journal of clinical pathology [J Clin Pathol] 2021 Apr; Vol. 74 (4), pp. 264-268. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Mismatch Repair*
Mutation*
Adenoma/*genetics
Biomarkers, Tumor/*genetics
Carcinoma/*genetics
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
DNA Repair Enzymes/*genetics
Adenoma/enzymology ; Adenoma/pathology ; Adenoma/therapy ; Biomarkers, Tumor/metabolism ; Biopsy ; Carcinoma/enzymology ; Carcinoma/pathology ; Carcinoma/therapy ; Colorectal Neoplasms, Hereditary Nonpolyposis/enzymology ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; Colorectal Neoplasms, Hereditary Nonpolyposis/therapy ; DNA Repair Enzymes/metabolism ; Genetic Predisposition to Disease ; Humans ; Phenotype
Czasopismo naukowe
Tytuł :
Management strategies for the colonoscopic surveillance of people with Lynch syndrome during the COVID-19 pandemic.
Autorzy :
Monahan KJ; The Lynch Syndrome and Family Cancer Clinic, St Mark's Hospital and Academic Institute, Harrow, London, UK .; Imperial College London, London, UK.
Lincoln A; Comprehensive Cancer Centre, King's College London, London, UK.
East JE; Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, UK.
Benton S; NHS Bowel Cancer Screening South of England Hub, Royal Surrey County Hospital NHS Foundation Trust, Guildford, Surrey, UK.
Burn J; Institute of Human Genetics, Newcastle upon Tyne, UK.
DeSouza B; Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Hanson H; Clinical Genetics, St George's University Hospitals NHS Foundation Trust, London, UK.
Lalloo F; Genetic Medicine, Central Manchester University Hospitals Foundation Trust, Manchester, UK.
McVeigh T; Cancer Genetics Unit, Royal Marsden NHS Foundation Trust, London, UK.
Rutter MD; Gastroenterology, University Hospital of North Tees, Stockton-on-Tees, UK.; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Snape K; Clinical Genetics, St George's University Hospitals NHS Foundation Trust, London, UK.
Thomas HJW; The Lynch Syndrome and Family Cancer Clinic, St Mark's Hospital and Academic Institute, Harrow, London, UK.; Imperial College London, London, UK.
Sasieni P; Comprehensive Cancer Centre, King's College London, London, UK.
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Źródło :
Gut [Gut] 2021 Mar; Vol. 70 (3), pp. 624-626. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Letter; Comment
MeSH Terms :
COVID-19*
Colorectal Neoplasms*/epidemiology
Colorectal Neoplasms, Hereditary Nonpolyposis*/diagnosis
Colorectal Neoplasms, Hereditary Nonpolyposis*/epidemiology
Gastroenterology*
Colonoscopy ; Humans ; Pandemics ; SARS-CoV-2 ; United Kingdom
Opinia redakcyjna
Tytuł :
High tumor mutational burden and T-cell activation are associated with long-term response to anti-PD1 therapy in Lynch syndrome recurrent glioblastoma patient.
Autorzy :
Anghileri E; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy. .
Di Ianni N; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.; Laboratory of Immunotherapy of Brain Tumors, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Paterra R; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.
Langella T; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.
Zhao J; Institute for Cancer Genetics, University of Columbia, New York, NY, USA.
Eoli M; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.
Patanè M; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133, Milan, Italy.
Pollo B; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133, Milan, Italy.
Cuccarini V; Neuroradiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133, Milan, Italy.
Iavarone A; Institute for Cancer Genetics, Department of Neurology and Pathology, Columbia University Medical Center, New York, NY, USA.
Rabadan R; Institute for Cancer Genetics, University of Columbia, New York, NY, USA.
Finocchiaro G; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.
Pellegatta S; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.; Laboratory of Immunotherapy of Brain Tumors, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Mar; Vol. 70 (3), pp. 831-842. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Biomarkers, Tumor*
Mutation*
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
Glioblastoma/*pathology
T-Lymphocytes/*immunology
T-Lymphocytes/*metabolism
Adult ; Biopsy ; Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis ; Colorectal Neoplasms, Hereditary Nonpolyposis/drug therapy ; Combined Modality Therapy ; Female ; Glioblastoma/diagnostic imaging ; Glioblastoma/therapy ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Immunohistochemistry ; Magnetic Resonance Imaging ; Molecular Targeted Therapy ; Neoplasm Recurrence, Local ; Neuroimaging ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Retreatment ; T-Lymphocytes/drug effects ; Treatment Outcome ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Microsatellite-Instability-High Advanced Colorectal Cancer.
Autorzy :
Battistuzzi L; University of Genoa, Genoa, Italy.
Puccini A; IRCCS Ospedale Policlinico San Martino, Genoa, Italy .
Sciallero S; IRCCS Ospedale Policlinico San Martino, Genoa, Italy .
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Źródło :
The New England journal of medicine [N Engl J Med] 2021 Mar 11; Vol. 384 (10), pp. 971-972.
Typ publikacji :
Letter; Comment
MeSH Terms :
Antibodies, Monoclonal, Humanized*
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
Humans ; Microsatellite Repeats
Opinia redakcyjna
Tytuł :
Microsatellite-Instability-High Advanced Colorectal Cancer. Reply.
Autorzy :
Diaz LA Jr; Memorial Sloan Kettering Cancer Center, New York, NY .
Le DT; Johns Hopkins Medical Institutes, Baltimore, MD.
André T; Hôpital Saint Antoine, Paris, France.
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Źródło :
The New England journal of medicine [N Engl J Med] 2021 Mar 11; Vol. 384 (10), pp. 972-973.
Typ publikacji :
Letter; Comment
MeSH Terms :
Colorectal Neoplasms*/genetics
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
Humans ; Microsatellite Repeats
Opinia redakcyjna
Tytuł :
Ovarian cancer risk in Lynch syndrome: it's time to individualise.
Autorzy :
Ring KL; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Virginia Health System, Charlottesville, Virginia, USA.
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Źródło :
BJOG : an international journal of obstetrics and gynaecology [BJOG] 2021 Mar; Vol. 128 (4), pp. 737. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Colorectal Neoplasms, Hereditary Nonpolyposis*/epidemiology
Ovarian Neoplasms*/epidemiology
Carcinoma, Ovarian Epithelial ; Female ; Humans ; United Kingdom
Czasopismo naukowe
Tytuł :
Lynch Syndrome: Its Impact on Urothelial Carcinoma.
Autorzy :
Lindner AK; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Schachtner G; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Tulchiner G; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Thurnher M; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.; Immunotherapy Unit, Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Untergasser G; Department of Internal Medicine V, Medical University Innsbruck, 6020 Innsbruck, Austria.; Experimental Oncogenomic Group, Tyrolean Cancer Research Institute, 6020 Innsbruck, Austria.
Obrist P; Pathology Laboratory Obrist and Brunhuber, 6511 Zams, Austria.
Pipp I; Clinical Pathology and Cytodiagnostics, tirol-kliniken, 6020 Innsbruck, Austria.
Steinkohl F; Department of Radiology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Horninger W; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Culig Z; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Pichler R; Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 07; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genetic Predisposition to Disease*
Carcinoma/*genetics
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
Urothelium/*metabolism
Carcinoma/complications ; Carcinoma/pathology ; Colorectal Neoplasms, Hereditary Nonpolyposis/complications ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; DNA Mismatch Repair/genetics ; DNA-Binding Proteins/genetics ; Humans ; Microsatellite Instability ; Mismatch Repair Endonuclease PMS2/genetics ; MutL Protein Homolog 1/genetics ; MutS Homolog 2 Protein/genetics ; Urothelium/pathology
Czasopismo naukowe
Tytuł :
Where Did the Colon Cancer Go?
Autorzy :
Marques-de-Sá I; Department of Gastroenterology, Portuguese Oncology Institute of Porto, Portugal.
Pita I; Department of Gastroenterology, Portuguese Oncology Institute of Porto, Portugal.
Coimbra N; Department of Pathology, Portuguese Oncology Institute of Porto, Portugal.
Dinis-Ribeiro M; Department of Gastroenterology, Portuguese Oncology Institute of Porto, Portugal.; Faculty of Medicine, CINTESIS (Center for Health Technology and Services Research), University of Porto, Porto, Portugal.
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Źródło :
The American journal of gastroenterology [Am J Gastroenterol] 2021 Jan 01; Vol. 116 (1), pp. 10.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Colectomy*
Adenocarcinoma/*pathology
Cecal Neoplasms/*pathology
Colorectal Neoplasms, Hereditary Nonpolyposis/*pathology
Neoplasm Regression, Spontaneous/*pathology
Adenocarcinoma/genetics ; Adenocarcinoma/surgery ; Cecal Neoplasms/genetics ; Cecal Neoplasms/surgery ; Colonoscopy ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/surgery ; DNA-Binding Proteins/metabolism ; Female ; Humans ; Hysterectomy ; Middle Aged ; MutS Homolog 2 Protein/genetics ; MutS Homolog 2 Protein/metabolism ; Prophylactic Surgical Procedures ; Salpingo-oophorectomy ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Molecular Features and Clinical Management of Hereditary Gynecological Cancers.
Autorzy :
Ueki A; Center for Medical Genetics, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Hirasawa A; Department of Clinical Genomic Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 14; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Breast Neoplasms/*metabolism
Breast Neoplasms/*pathology
Colorectal Neoplasms, Hereditary Nonpolyposis/*metabolism
Colorectal Neoplasms, Hereditary Nonpolyposis/*pathology
Hereditary Breast and Ovarian Cancer Syndrome/*pathology
Breast Neoplasms/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Female ; Genetic Predisposition to Disease/genetics ; Hereditary Breast and Ovarian Cancer Syndrome/genetics ; Hereditary Breast and Ovarian Cancer Syndrome/metabolism ; High-Throughput Nucleotide Sequencing ; Humans
SCR Disease Name :
Breast Cancer, Familial
Czasopismo naukowe
Tytuł :
[A Family with Lynch Syndrome Diagnosed after a Proband of Elderly Multiple Colorectal Cancers].
Autorzy :
Chika N; Dept. of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University.
Murakami T
Kamae N
Suzuki O
Mori Y
Sakimoto T
Ishiguro T
Kumagai Y
Eguchi H
Ishibashi K
Mochiki E
Okazaki Y
Iwama T
Ishida H
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Źródło :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2020 Dec; Vol. 47 (13), pp. 1909-1912.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Colorectal Neoplasms*
Colorectal Neoplasms, Hereditary Nonpolyposis*/diagnosis
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
Colorectal Neoplasms, Hereditary Nonpolyposis*/surgery
Aged ; DNA Mismatch Repair/genetics ; Genetic Testing ; Humans ; Male ; Microsatellite Instability ; Middle Aged ; MutL Protein Homolog 1 ; MutS Homolog 2 Protein/genetics
Czasopismo naukowe
Tytuł :
[Cancer Risk in Lynch Syndrome-Associated Endometrial Cancer Patients and Their Relatives].
Autorzy :
Yamamoto A; Dept. of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University.
Mori Y
Suzuki O
Ishibashi K
Kamae N
Yoshida H
Hasegawa K
Fujiwara K
Eguchi H
Okazaki Y
Akagi K
Ishida H
Pokaż więcej
Źródło :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2020 Dec; Vol. 47 (13), pp. 2257-2259.
Typ publikacji :
Journal Article
MeSH Terms :
Colorectal Neoplasms*
Colorectal Neoplasms, Hereditary Nonpolyposis*/complications
Colorectal Neoplasms, Hereditary Nonpolyposis*/epidemiology
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
Endometrial Neoplasms*/epidemiology
DNA Mismatch Repair/genetics ; Female ; Humans ; Incidence ; Japan
Czasopismo naukowe
Tytuł :
Candidate Gene Discovery in Hereditary Colorectal Cancer and Polyposis Syndromes-Considerations for Future Studies.
Autorzy :
Te Paske IBAW; Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Ligtenberg MJL; Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Hoogerbrugge N; Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
de Voer RM; Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 19; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genetic Loci*
Adenomatous Polyposis Coli/*genetics
Adenomatous Polyposis Coli Protein/*genetics
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
PTEN Phosphohydrolase/*genetics
Adenomatous Polyposis Coli/diagnosis ; Adenomatous Polyposis Coli/metabolism ; Adenomatous Polyposis Coli/pathology ; Adenomatous Polyposis Coli Protein/metabolism ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis ; Colorectal Neoplasms, Hereditary Nonpolyposis/metabolism ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; Exome ; Genetic Association Studies ; Genetic Predisposition to Disease ; Genotype ; Humans ; MutL Protein Homolog 1/genetics ; MutL Protein Homolog 1/metabolism ; MutS Homolog 2 Protein/genetics ; MutS Homolog 2 Protein/metabolism ; PTEN Phosphohydrolase/metabolism ; Penetrance ; Phenotype ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
The study of Lynch syndrome in a special population reveals a strong founder effect and an unusual mutational mechanism in familial adenomatous polyposis.
Autorzy :
Siraj AK; Human Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Masoodi T; Human Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Bu R; Human Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Parvathareddy SK; Human Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Siraj S; Human Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Alassiri A; Department of Pediatric Surgery, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Al-Dayel F; Department of Pathology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Alkuraya FS; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Al-Kuraya KS; Human Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia .
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Źródło :
Gut [Gut] 2020 Nov; Vol. 69 (11), pp. 2048-2049. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji :
Letter; Comment
MeSH Terms :
Adenomatous Polyposis Coli*/genetics
Colorectal Neoplasms, Hereditary Nonpolyposis*/epidemiology
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
Founder Effect ; Humans ; Mutation ; Prospective Studies
Opinia redakcyjna
Tytuł :
Exploring the real-world effect of the SARS-CoV-2 pandemic on the molecular diagnostics for cancer patients and high-risk individuals.
Autorzy :
Cavic M; Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Krivokuca A; Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Boljevic I; Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Spasic J; Clinic for Medical Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Mihajlovic M; Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Pavlovic M; Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Damjanovic A; Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Radosavljevic D; Clinic for Medical Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Jankovic R; Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
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Źródło :
Expert review of molecular diagnostics [Expert Rev Mol Diagn] 2021 Jan; Vol. 21 (1), pp. 101-107. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Breast Neoplasms/*diagnosis
Colorectal Neoplasms, Hereditary Nonpolyposis/*diagnosis
Ovarian Neoplasms/*diagnosis
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Breast Neoplasms/genetics ; COVID-19 ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; DNA Mutational Analysis ; ErbB Receptors/genetics ; Female ; GTP Phosphohydrolases/genetics ; Genetic Counseling ; Genetic Predisposition to Disease ; Humans ; Liquid Biopsy ; Membrane Proteins/genetics ; Ovarian Neoplasms/genetics ; Pandemics ; Pathology, Molecular ; Pharmacogenetics ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins p21(ras)/genetics ; Serbia/epidemiology
Czasopismo naukowe
Tytuł :
The clinical utility of microsatellite instability in colorectal cancer.
Autorzy :
Diao Z; National Center for Clinical Laboratories, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, PR China; Peking University Fifth School of Clinical Medicine, Beijing Hospital, Beijing, PR China; Beijing Engineering Research Center of Laboratory Medicine, Beijing, PR China.
Han Y; National Center for Clinical Laboratories, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, PR China; Beijing Engineering Research Center of Laboratory Medicine, Beijing, PR China.
Chen Y; National Center for Clinical Laboratories, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, PR China; Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, PR China; Beijing Engineering Research Center of Laboratory Medicine, Beijing, PR China.
Zhang R; National Center for Clinical Laboratories, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, PR China; Beijing Engineering Research Center of Laboratory Medicine, Beijing, PR China. Electronic address: .
Li J; National Center for Clinical Laboratories, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, PR China. Electronic address: .
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Źródło :
Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2021 Jan; Vol. 157, pp. 103171. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Colorectal Neoplasms*/diagnosis
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/therapy
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
DNA Mismatch Repair/genetics ; Humans ; Microsatellite Instability ; Microsatellite Repeats ; Prognosis
Czasopismo naukowe
Tytuł :
[A Case of Lynch Syndrome with Seven Cancers in Five Organs].
Autorzy :
Nakagawa T; Dept. of Specialized Surgeries, Tokyo Medical and Dental University.
Oda G
Kumaki Y
Wakana K
Oshima N
Nakamura R
Takahashi K
Yoshida M
Koubata H
Uetake H
Onishi I
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Źródło :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2020 Dec; Vol. 47 (13), pp. 1966-1968.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Breast Neoplasms*
Colonic Neoplasms*/genetics
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
Female ; Humans
Czasopismo naukowe
Tytuł :
An Analysis of Clinical, Surgical, Pathological and Molecular Characteristics of Endometrial Cancer According to Mismatch Repair Status. A Multidisciplinary Approach.
Autorzy :
Dondi G; Gynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.; Centro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.
Coluccelli S; Gynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.; Centro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.; Center for Applied Biomedical Research, Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.
De Leo A; Centro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.; Molecular Diagnostic Unit, Azienda USL Bologna, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, 40138 Bologna, Italy.
Ferrari S; Unit of Medical Genetics, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, University of Bologna, 40138 Bologna, Italy.
Gruppioni E; Laboratory of Oncologic and Transplantation Molecular Pathology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, 40138 Bologna, Italy.
Bovicelli A; Gynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.
Godino L; Unit of Medical Genetics, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, University of Bologna, 40138 Bologna, Italy.
Coadă CA; Center for Applied Biomedical Research, Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.
Morganti AG; Centro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.; Radiation Oncology Center, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, 40138 Bologna, Italy.
Giordano A; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA 19122, USA.; Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Santini D; Centro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.; Pathology Unit Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.
Ceccarelli C; Centro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.; Molecular Diagnostic Unit, Azienda USL Bologna, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, 40138 Bologna, Italy.
Turchetti D; Centro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.; Unit of Medical Genetics, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, University of Bologna, 40138 Bologna, Italy.
De Iaco P; Gynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.; Centro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.
Perrone AM; Gynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, 40138 Bologna, Italy.; Centro di Studio e Ricerca delle Neoplasie Ginecologiche (CSR), University of Bologna, 40138 Bologna, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 29; Vol. 21 (19). Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article
MeSH Terms :
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
DNA Mismatch Repair/*genetics
Endometrial Neoplasms/*genetics
MutL Protein Homolog 1/*genetics
Adult ; Biomarkers, Tumor/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; DNA Methylation/genetics ; DNA-Binding Proteins/genetics ; Early Detection of Cancer ; Endometrial Neoplasms/diagnosis ; Endometrial Neoplasms/pathology ; Female ; Genetic Predisposition to Disease ; Germ-Line Mutation/genetics ; Humans ; Male ; Microsatellite Instability ; Middle Aged ; Promoter Regions, Genetic/genetics
Czasopismo naukowe
Tytuł :
Microsatellite instability driven metastatic parathyroid carcinoma managed with the anti-PD1 immunotherapy, pembrolizumab.
Autorzy :
Park D; Internal Medicine, Touro University California, Vallejo, California, USA .
Airi R; Internal Medicine, Touro University California, Vallejo, California, USA.
Sherman M; Hematolgy & Oncology, Contra Costa Oncology, Walnut Creek, California, USA.
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Źródło :
BMJ case reports [BMJ Case Rep] 2020 Sep 23; Vol. 13 (9). Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Microsatellite Instability*
Antibodies, Monoclonal, Humanized/*therapeutic use
Colorectal Neoplasms, Hereditary Nonpolyposis/*complications
Lung Neoplasms/*drug therapy
Parathyroid Neoplasms/*therapy
Aged ; Biomarkers, Tumor/genetics ; Biopsy ; Calcium/blood ; Chemotherapy, Adjuvant/methods ; Colorectal Neoplasms, Hereditary Nonpolyposis/blood ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/therapy ; DNA Mutational Analysis ; Humans ; Hypercalcemia/diagnosis ; Hypercalcemia/genetics ; Hypercalcemia/therapy ; Hyperparathyroidism/diagnosis ; Hyperparathyroidism/genetics ; Hyperparathyroidism/therapy ; Lung/diagnostic imaging ; Lung/pathology ; Lung Neoplasms/genetics ; Lung Neoplasms/secondary ; Male ; Parathyroid Glands/diagnostic imaging ; Parathyroid Glands/pathology ; Parathyroid Glands/surgery ; Parathyroid Hormone/blood ; Parathyroid Neoplasms/diagnosis ; Parathyroid Neoplasms/genetics ; Parathyroid Neoplasms/pathology ; Parathyroidectomy ; Positron Emission Tomography Computed Tomography ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Tomography, Emission-Computed, Single-Photon ; Treatment Outcome ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
The proportion of endometrial tumours associated with Lynch syndrome (PETALS): A prospective cross-sectional study.
Autorzy :
Ryan NAJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.; Division of Evolution and Genomic Medicine, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
McMahon R; Department of Pathology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Tobi S; Manchester Centre for Genomic Medicine, North-West Genomics Laboratory Hub, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Snowsill T; Health Economics Group, University of Exeter Medical School, University of Exeter, Exeter, Devon, United Kingdom.
Esquibel S; Department of Pathology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Wallace AJ; Manchester Centre for Genomic Medicine, North-West Genomics Laboratory Hub, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Bunstone S; Manchester Centre for Genomic Medicine, North-West Genomics Laboratory Hub, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Bowers N; Manchester Centre for Genomic Medicine, North-West Genomics Laboratory Hub, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Mosneag IE; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Kitson SJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
O'Flynn H; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Ramchander NC; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Sivalingam VN; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Frayling IM; Inherited Tumour Syndromes Research Group, Institute of Cancer & Genetics, Cardiff University, Cardiff, United Kingdom.
Bolton J; Department of Pathology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
McVey RJ; Department of Pathology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Evans DG; Division of Evolution and Genomic Medicine, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.; Manchester Centre for Genomic Medicine, North-West Genomics Laboratory Hub, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Crosbie EJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.; Department of Obstetrics and Gynaecology, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
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Źródło :
PLoS medicine [PLoS Med] 2020 Sep 17; Vol. 17 (9), pp. e1003263. Date of Electronic Publication: 2020 Sep 17 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colorectal Neoplasms, Hereditary Nonpolyposis/*diagnosis
Early Detection of Cancer/*methods
Endometrial Neoplasms/*genetics
Adult ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; Cross-Sectional Studies ; DNA Methylation/genetics ; DNA Mismatch Repair/genetics ; Endometrial Neoplasms/diagnosis ; Female ; Genetic Testing/methods ; Humans ; Immunohistochemistry ; Mass Screening/methods ; Microsatellite Instability ; Middle Aged ; Prospective Studies ; Sensitivity and Specificity ; United Kingdom
Czasopismo naukowe

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