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Wyszukujesz frazę ""Combinatorial chemistry"" wg kryterium: Temat


Tytuł:
Calculating and Optimizing Physicochemical Property Distributions of Large Combinatorial Fragment Spaces.
Autorzy:
Bellmann L; Universität Hamburg, ZBH - Center for Bioinformatics, Research Group for Computational Molecular Design, Bundesstraße 43, 20146 Hamburg, Germany.
Klein R; BioSolveIT GmbH, An der Ziegelei 79, 53757 Sankt Augustin, Germany.
Rarey M; Universität Hamburg, ZBH - Center for Bioinformatics, Research Group for Computational Molecular Design, Bundesstraße 43, 20146 Hamburg, Germany.
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Źródło:
Journal of chemical information and modeling [J Chem Inf Model] 2022 Jun 13; Vol. 62 (11), pp. 2800-2810. Date of Electronic Publication: 2022 Jun 02.
Typ publikacji:
Journal Article
MeSH Terms:
Combinatorial Chemistry Techniques*
Small Molecule Libraries*
Czasopismo naukowe
Tytuł:
One-pot parallel synthesis of 1,3,5-trisubstituted 1,2,4-triazoles.
Autorzy:
Radchenko DS; Enamine Ltd., Chervonotkatska Street 78, Kyiv, 02094, Ukraine.; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv, 01601, Ukraine.
Naumchyk VS; Enamine Ltd., Chervonotkatska Street 78, Kyiv, 02094, Ukraine.
Dziuba I; Chemspace, Chervonotkatska Street 78, Kyiv, 02094, Ukraine.
Kyrylchuk AA; Enamine Ltd., Chervonotkatska Street 78, Kyiv, 02094, Ukraine.; Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Murmanska Street 5, Kyiv, 02094, Ukraine.
Gubina KE; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv, 01601, Ukraine.
Moroz YS; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv, 01601, Ukraine.; Chemspace, Chervonotkatska Street 78, Kyiv, 02094, Ukraine.
Grygorenko OO; Enamine Ltd., Chervonotkatska Street 78, Kyiv, 02094, Ukraine. .; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv, 01601, Ukraine. .
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Źródło:
Molecular diversity [Mol Divers] 2022 Apr; Vol. 26 (2), pp. 993-1004. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Combinatorial Chemistry Techniques*/methods
Triazoles*/chemistry
Cyclization ; Hydrazines/chemistry ; Molecular Structure
Czasopismo naukowe
Tytuł:
Comparison of Combinatorial Fragment Spaces and Its Application to Ultralarge Make-on-Demand Compound Catalogs.
Autorzy:
Bellmann L; Universität Hamburg, ZBH - Center for Bioinformatics, Research Group for Computational Molecular Design, Bundesstraße 43, 20146 Hamburg, Germany.
Penner P; Universität Hamburg, ZBH - Center for Bioinformatics, Research Group for Computational Molecular Design, Bundesstraße 43, 20146 Hamburg, Germany.
Gastreich M; BioSolveIT GmbH, An der Ziegelei 79, 53757 Sankt Augustin, Germany.
Rarey M; Universität Hamburg, ZBH - Center for Bioinformatics, Research Group for Computational Molecular Design, Bundesstraße 43, 20146 Hamburg, Germany.
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Źródło:
Journal of chemical information and modeling [J Chem Inf Model] 2022 Feb 14; Vol. 62 (3), pp. 553-566. Date of Electronic Publication: 2022 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Combinatorial Chemistry Techniques*
Small Molecule Libraries*/chemistry
Czasopismo naukowe
Tytuł:
Synthon-based ligand discovery in virtual libraries of over 11 billion compounds.
Autorzy:
Sadybekov AA; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USA.; Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.
Sadybekov AV; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USA.; Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.
Liu Y; Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.; Psychoactive Drug Screening Program, National Institute of Mental Health, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Iliopoulos-Tsoutsouvas C; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA.
Huang XP; Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.; Psychoactive Drug Screening Program, National Institute of Mental Health, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Pickett J; Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.; Psychoactive Drug Screening Program, National Institute of Mental Health, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Houser B; Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.
Patel N; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USA.
Tran NK; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA.
Tong F; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA.
Zvonok N; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA.
Jain MK; Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Savych O; Enamine Ltd, Kyiv, Ukraine.
Radchenko DS; Enamine Ltd, Kyiv, Ukraine.; Taras Shevchenko National University of Kyiv, Kyiv, Ukraine.
Nikas SP; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA.
Petasis NA; Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.
Moroz YS; Taras Shevchenko National University of Kyiv, Kyiv, Ukraine.; Chemspace LLC, Kyiv, Ukraine.
Roth BL; Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA. bryan_.; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA. bryan_.; Psychoactive Drug Screening Program, National Institute of Mental Health, School of Medicine, University of North Carolina, Chapel Hill, NC, USA. bryan_.
Makriyannis A; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA. .; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA. .
Katritch V; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USA. .; Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA. .
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Źródło:
Nature [Nature] 2022 Jan; Vol. 601 (7893), pp. 452-459. Date of Electronic Publication: 2021 Dec 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Algorithms*
Combinatorial Chemistry Techniques*
Drug Discovery*
Libraries, Digital*
Ligands ; Molecular Docking Simulation ; rho-Associated Kinases
Czasopismo naukowe
Tytuł:
Bioinspired Screening of Anti-Adhesion Peptides against Blood Proteins for Intravenous Delivery of Nanomaterials.
Autorzy:
Li YJ; State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China.
Zhang L; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China.
Yang PP; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China.
Zhang K; State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China.
Gong XF; State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China.
Hou DY; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China.
Cao H; State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China.
Wu XC; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China.
Liu R; Department of Biochemistry and Molecular Medicine, UC Davis NCI-designated Comprehensive Cancer Center, University of California Davis, Sacramento, California 95817, United States.
Lam KS; Department of Biochemistry and Molecular Medicine, UC Davis NCI-designated Comprehensive Cancer Center, University of California Davis, Sacramento, California 95817, United States.; Division of Hematology and Oncology, Department of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California 95817, United States.
Wang L; CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China.
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Źródło:
Nano letters [Nano Lett] 2022 Oct 26; Vol. 22 (20), pp. 8076-8085. Date of Electronic Publication: 2022 Sep 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Library*
Nanostructures*
Mice ; Animals ; Combinatorial Chemistry Techniques/methods ; Tissue Distribution ; Peptides/pharmacology ; Peptides/chemistry ; Blood Proteins ; Administration, Intravenous ; Gold ; Drug Carriers
Czasopismo naukowe
Tytuł:
A high-throughput pipeline for design and selection of peptides targeting the SARS-Cov-2 Spike protein.
Autorzy:
Wolfe M; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH, 45433, USA.; UES, Inc., Dayton, OH, 45432, USA.
Webb S; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH, 45433, USA.; UES, Inc., Dayton, OH, 45432, USA.
Chushak Y; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH, 45433, USA.; Henry M. Jackson Foundation, Dayton, OH, 45433, USA.
Krabacher R; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH, 45433, USA.; Materials & Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH, 45433, USA.
Liu Y; Department of Electrical and Computer Engineering, University of Virginia, Charlottesville, VA, 22904, USA.
Swami N; Department of Electrical and Computer Engineering, University of Virginia, Charlottesville, VA, 22904, USA.
Harbaugh S; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH, 45433, USA.
Chávez J; 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH, 45433, USA. jorge.chavez_.
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 05; Vol. 11 (1), pp. 21768. Date of Electronic Publication: 2021 Nov 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Combinatorial Chemistry Techniques*
SARS-CoV-2*
COVID-19/*immunology
Peptides/*chemistry
Spike Glycoprotein, Coronavirus/*chemistry
COVID-19/virology ; Computational Biology ; Electrochemistry/methods ; Enzyme-Linked Immunosorbent Assay ; Humans ; Interferometry ; Kinetics ; Peptide Library ; Protein Array Analysis ; Protein Engineering ; Saliva/immunology
Czasopismo naukowe
Tytuł:
Sequential DNA-Encoded Building Block Fusion for the Construction of Polysubstituted Pyrazoline Core Libraries.
Autorzy:
Zhang J; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, P. R. China.
Li X; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, P. R. China.
Wei H; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, P. R. China.
Li Y; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, P. R. China.
Zhang G; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, P. R. China.
Li Y; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, P. R. China.; Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, P. R. China.
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Źródło:
Organic letters [Org Lett] 2021 Nov 05; Vol. 23 (21), pp. 8429-8433. Date of Electronic Publication: 2021 Oct 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Combinatorial Chemistry Techniques*
Czasopismo naukowe
Tytuł:
Dynamic Amino Acid Side-Chains Grafting on Folded Peptide Backbone.
Autorzy:
Zagiel B; Sorbonne Université, École normale supérieure, PSL University, CNRS, Laboratoire des biomolécules, LBM, 75005, Paris, France.
Peker T; Sorbonne Université, École normale supérieure, PSL University, CNRS, Laboratoire des biomolécules, LBM, 75005, Paris, France.
Marquant R; Sorbonne Université, École normale supérieure, PSL University, CNRS, Laboratoire des biomolécules, LBM, 75005, Paris, France.
Cazals G; UMR 5247-CNRS-UM-ENSCM, Institut des Biomolécules Max Mousseron (IBMM), Université de Montpellier, 34293, Montpellier, France.
Webb G; Sorbonne Université, École normale supérieure, PSL University, CNRS, Laboratoire des biomolécules, LBM, 75005, Paris, France.
Miclet E; Sorbonne Université, École normale supérieure, PSL University, CNRS, Laboratoire des biomolécules, LBM, 75005, Paris, France.
Bich C; UMR 5247-CNRS-UM-ENSCM, Institut des Biomolécules Max Mousseron (IBMM), Université de Montpellier, 34293, Montpellier, France.
Sachon E; Sorbonne Université, École normale supérieure, PSL University, CNRS, Laboratoire des biomolécules, LBM, 75005, Paris, France.; MS3 U platform, UFR 926, UFR 927, Sorbonne Université, 4 place Jussieu, 75005, Paris, France.
Moumné R; Sorbonne Université, École normale supérieure, PSL University, CNRS, Laboratoire des biomolécules, LBM, 75005, Paris, France.
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Źródło:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Jun 27; Vol. 28 (36), pp. e202200454. Date of Electronic Publication: 2022 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Amino Acids*
Peptide Library*
Combinatorial Chemistry Techniques/methods ; Peptides/chemistry ; Proteins
Czasopismo naukowe
Tytuł:
Proteomic Tools for the Quantitative Analysis of Artificial Peptide Libraries: Detection and Characterization of Target-Amplified PD-1 Inhibitors.
Autorzy:
Gay M; Institute for Research in Biomedicine (IRB Barcelona), BIST (Barcelona Institute of Science and Technology), Baldiri Reixac 10, Barcelona, 08028, Spain.
Díaz-Lobo M; Institute for Research in Biomedicine (IRB Barcelona), BIST (Barcelona Institute of Science and Technology), Baldiri Reixac 10, Barcelona, 08028, Spain.
Gusi-Vives M; Institute for Research in Biomedicine (IRB Barcelona), BIST (Barcelona Institute of Science and Technology), Baldiri Reixac 10, Barcelona, 08028, Spain.
Arauz-Garofalo G; Institute for Research in Biomedicine (IRB Barcelona), BIST (Barcelona Institute of Science and Technology), Baldiri Reixac 10, Barcelona, 08028, Spain.
Vilanova M; Institute for Research in Biomedicine (IRB Barcelona), BIST (Barcelona Institute of Science and Technology), Baldiri Reixac 10, Barcelona, 08028, Spain.
Giralt E; Institute for Research in Biomedicine (IRB Barcelona), BIST (Barcelona Institute of Science and Technology), Baldiri Reixac 10, Barcelona, 08028, Spain.; Department of Inorganic and Organic Chemistry, Universitat de Barcelona, Martí Franques 1-11, Barcelona, 08028, Spain.
Vilaseca M; Institute for Research in Biomedicine (IRB Barcelona), BIST (Barcelona Institute of Science and Technology), Baldiri Reixac 10, Barcelona, 08028, Spain.
Guardiola S; Institute for Research in Biomedicine (IRB Barcelona), BIST (Barcelona Institute of Science and Technology), Baldiri Reixac 10, Barcelona, 08028, Spain.
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Źródło:
Chembiochem : a European journal of chemical biology [Chembiochem] 2022 Jun 20; Vol. 23 (12), pp. e202200152. Date of Electronic Publication: 2022 Apr 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Library*
Proteomics*/methods
Combinatorial Chemistry Techniques/methods ; Immune Checkpoint Inhibitors ; Peptides/chemistry ; Programmed Cell Death 1 Receptor ; Proteins
Czasopismo naukowe
Tytuł:
New Phenylglycinamide Derivatives with Hybrid Structure as Candidates for New Broad-Spectrum Anticonvulsants.
Autorzy:
Jakubiec, Marcin (AUTHOR)
Abram, Michał (AUTHOR)
Zagaja, Mirosław (AUTHOR)
Andres-Mach, Marta (AUTHOR)
Szewczyk, Aleksandra (AUTHOR)
Latacz, Gniewomir (AUTHOR)
Szulczyk, Bartłomiej (AUTHOR)
Socała, Katarzyna (AUTHOR)
Nieoczym, Dorota (AUTHOR)
Wlaź, Piotr (AUTHOR)
Metcalf, Cameron S. (AUTHOR)
Wilcox, Karen (AUTHOR)
Kamiński, Rafał M. (AUTHOR)
Kamiński, Krzysztof (AUTHOR)
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Źródło:
Cells (2073-4409). Jun2022, Vol. 11 Issue 12, p1862-N.PAG. 35p.
Czasopismo naukowe
Tytuł:
Diversity-oriented synthesis as a tool to expand the chemical space of DNA-encoded libraries.
Autorzy:
Lenci E; Department of Chemistry 'Ugo Schiff', University of Florence, Via della Lastruccia 13, 50019 Sesto Fiorentino, Italy.
Baldini L; Department of Chemistry 'Ugo Schiff', University of Florence, Via della Lastruccia 13, 50019 Sesto Fiorentino, Italy.
Trabocchi A; Department of Chemistry 'Ugo Schiff', University of Florence, Via della Lastruccia 13, 50019 Sesto Fiorentino, Italy; Interdepartmental Center for Preclinical Development of Molecular Imaging (CISPIM), University of Florence, Viale Morgagni 85, 50134 Florence, Italy. Electronic address: .
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Źródło:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2021 Jul 01; Vol. 41, pp. 116218. Date of Electronic Publication: 2021 May 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Combinatorial Chemistry Techniques*
Small Molecule Libraries*
DNA/*chemistry
Drug Discovery/*methods
Gene Library
Czasopismo naukowe
Tytuł:
Comparative analysis of an anthraquinone and chalcone derivatives-based virtual combinatorial library. A cheminformatics "proof-of-concept" study.
Autorzy:
Moshawih S; PAP Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong, Brunei Darussalam. Electronic address: .
Hadikhani P; Institute of Applied Data Analytics, Universiti Brunei Darussalam, Gadong, Brunei Darussalam.
Fatima A; Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Istanbul, Turkey.
Goh HP; PAP Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong, Brunei Darussalam.
Kifli N; PAP Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong, Brunei Darussalam.
Kotra V; Faculty of Pharmacy, Quest International University, Ipoh, Malaysia.
Goh KW; Faculty of Data Science and Information Technology, INTI International University, Nilai, Malaysia.
Ming LC; PAP Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong, Brunei Darussalam. Electronic address: .
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Źródło:
Journal of molecular graphics & modelling [J Mol Graph Model] 2022 Dec; Vol. 117, pp. 108307. Date of Electronic Publication: 2022 Aug 15.
Typ publikacji:
Journal Article
MeSH Terms:
Biological Products*/chemistry
Chalcone*
Chalcones*
Anthraquinones ; Cheminformatics ; Combinatorial Chemistry Techniques/methods ; Drug Design ; Zinc
Czasopismo naukowe
Tytuł:
Multivalent butyrylcholinesterase inhibitor discovered by exploiting dynamic combinatorial chemistry.
Autorzy:
Zhao S; School of Pharmacy, Jiangsu University, 301 Xuefu Rd., Zhenjiang, China.
Xu J; School of Pharmacy, Jiangsu University, 301 Xuefu Rd., Zhenjiang, China.
Zhang S; School of Pharmacy, Jiangsu University, 301 Xuefu Rd., Zhenjiang, China.
Han M; School of Pharmacy, Jiangsu University, 301 Xuefu Rd., Zhenjiang, China.
Wu Y; School of Pharmacy, Jiangsu University, 301 Xuefu Rd., Zhenjiang, China.
Li Y; School of Pharmacy, Jiangsu University, 301 Xuefu Rd., Zhenjiang, China.
Hu L; School of Pharmacy, Jiangsu University, 301 Xuefu Rd., Zhenjiang, China. Electronic address: .
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Źródło:
Bioorganic chemistry [Bioorg Chem] 2021 Mar; Vol. 108, pp. 104656. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Combinatorial Chemistry Techniques*
Drug Discovery*
Butyrylcholinesterase/*metabolism
Cholinesterase Inhibitors/*pharmacology
Acetylcholinesterase/metabolism ; Cell Line, Tumor ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Humans ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
High-Throughput and Combinatorial Approaches for the Development of Multifunctional Polymers.
Autorzy:
Baudis S; Institute of Active Polymers, Helmholtz-Zentrum Hereon, 14513, Teltow, Germany.
Behl M; Institute of Active Polymers, Helmholtz-Zentrum Hereon, 14513, Teltow, Germany.
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Źródło:
Macromolecular rapid communications [Macromol Rapid Commun] 2022 Jun; Vol. 43 (12), pp. e2100400. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Polymers*/chemistry
Spectrometry, Mass, Secondary Ion*
Combinatorial Chemistry Techniques/methods ; Photoelectron Spectroscopy
Czasopismo naukowe
Tytuł:
Synthesis and Screening of a DNA-Encoded Library of Non-Peptidic Macrocycles.
Autorzy:
Koesema E; Deluge Biotechnologies, 6671 W. Indiantown Rd., Suite 50-325, Jupiter, FL 33458, USA.
Roy A; Deluge Biotechnologies, 6671 W. Indiantown Rd., Suite 50-325, Jupiter, FL 33458, USA.
Paciaroni NG; Deluge Biotechnologies, 6671 W. Indiantown Rd., Suite 50-325, Jupiter, FL 33458, USA.
Coito C; Deluge Biotechnologies, 6671 W. Indiantown Rd., Suite 50-325, Jupiter, FL 33458, USA.
Tokmina-Roszyk M; Department of Chemistry, Scripps Florida, 130 Scripps Way, Jupiter, FL 33458, USA.
Kodadek T; Department of Chemistry, Scripps Florida, 130 Scripps Way, Jupiter, FL 33458, USA.; Deluge Biotechnologies, 6671 W. Indiantown Rd., Suite 50-325, Jupiter, FL 33458, USA.
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Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Apr 25; Vol. 61 (18), pp. e202116999. Date of Electronic Publication: 2022 Mar 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
DNA*/chemistry
Solid-Phase Synthesis Techniques*/methods
Combinatorial Chemistry Techniques ; Gene Library ; Ligands
Czasopismo naukowe
Tytuł:
Exploring Aldol Reactions on DNA and Applications to Produce Diverse Structures: An Example of Expanding Chemical Space of DNA-Encoded Compounds by Diversity-Oriented Synthesis.
Autorzy:
Wu R; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
Gao S; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
Du T; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
Cai K; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
Cheng X; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
Fan J; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
Feng J; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
Shaginian A; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
Li J; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
Wan J; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
Liu G; HitGen Inc. Building 6, No 8 Huigu 1st East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, 610200, Sichuan, P. R. China.
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Źródło:
Chemistry, an Asian journal [Chem Asian J] 2020 Dec 01; Vol. 15 (23), pp. 4033-4037. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji:
Journal Article
MeSH Terms:
Combinatorial Chemistry Techniques*
Small Molecule Libraries*
DNA/*chemistry
Hydrocarbons/*chemical synthesis
Drug Discovery ; Hydrocarbons/chemistry ; Molecular Structure ; Nucleic Acid Conformation ; Substrate Specificity
Czasopismo naukowe
Tytuł:
D-Peptide Builder: A Web Service to Enumerate, Analyze, and Visualize the Chemical Space of Combinatorial Peptide Libraries.
Autorzy:
Díaz-Eufracio BI; DIFACQUIM research group, Department of Pharmacy, School of Chemistry, Universidad Nacional Autónoma de México, Avenida Universidad 3000, 04510, Mexico City, Mexico.
Palomino-Hernández O; Computational Biomedicine, Institute of Advanced Simulation (IAS-5), and Institute of Neuroscience and Medicine (INM-9), Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
Arredondo-Sánchez A; DIFACQUIM research group, Department of Pharmacy, School of Chemistry, Universidad Nacional Autónoma de México, Avenida Universidad 3000, 04510, Mexico City, Mexico.
Medina-Franco JL; DIFACQUIM research group, Department of Pharmacy, School of Chemistry, Universidad Nacional Autónoma de México, Avenida Universidad 3000, 04510, Mexico City, Mexico.
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Źródło:
Molecular informatics [Mol Inform] 2020 Nov; Vol. 39 (11), pp. e2000035. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Combinatorial Chemistry Techniques*
Internet*
Peptide Library*
Peptides/*chemistry
User-Computer Interface
Czasopismo naukowe
Tytuł:
Live-Cell-Templated Dynamic Combinatorial Chemistry.
Autorzy:
Carbajo D; Department of Biological Chemistry, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain.
Pérez Y; NMR Facility (IQAC-CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain.
Bujons J; Department of Biological Chemistry, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain.
Alfonso I; Department of Biological Chemistry, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain.
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Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2020 Sep 21; Vol. 59 (39), pp. 17202-17206. Date of Electronic Publication: 2020 May 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Combinatorial Chemistry Techniques*
Extracellular Matrix/*chemistry
Imines/*chemistry
Polyamines/*chemistry
A549 Cells ; Humans ; Ligands ; Molecular Dynamics Simulation
Czasopismo naukowe

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