Temat: "Comparative Genomic Hybridization" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Meta-analysis of adrenocortical tumour genomics data: novel pathogenic pathways revealed.
Autorzy:: Szabó PM; 2nd Department of Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Tamási V
Molnár V
Andrásfalvy M
Tömböl Z
Farkas R
Kövesdi K
Patócs A
Tóth M
Szalai C
Falus A
Rácz K
Igaz P; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2010 May 27; Vol. 29 (21), pp. 3163-72. Date of Electronic Publication: 2010 Mar 22.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms:: Comparative Genomic Hybridization*
Genomics*
Meta-Analysis as Topic*
Adrenal Cortex Neoplasms/*genetics
Chromosome Aberrations ; Gene Expression Profiling ; Humans ; Oligonucleotide Array Sequence Analysis ; RNA, Messenger/genetics ; RNA, Neoplasm/genetics

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Skocz do pozycji: 2.

Tytuł:: Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer.
Autorzy:: Hosoda F; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Arai Y; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Okada N; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Shimizu H; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Miyamoto M; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Kitagawa N; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Katai H; Division of Gastric Surgery, National Cancer Center Hospital, Tokyo, Japan.
Taniguchi H; Division of Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan.
Yanagihara K; Division of Translational Research, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Chiba, Japan.
Imoto I; 1] Department of Molecular Cytogenetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan [2] Department of Human Genetics and Public Health, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.
Inazawa J; Department of Molecular Cytogenetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Ohki M; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
Shibata T; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2015 Feb 26; Vol. 34 (9), pp. 1196-206. Date of Electronic Publication: 2014 Mar 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Chromosomes, Human, Pair 6/*genetics
Genomics/*methods
Lactoylglutathione Lyase/*genetics
Receptor, ErbB-2/*genetics
Stomach Neoplasms/*genetics
Animals ; Cell Line, Tumor ; Comparative Genomic Hybridization ; Gene Amplification ; Gene Dosage ; Glutathione/analogs & derivatives ; Glutathione/metabolism ; HEK293 Cells ; Humans ; Lactoylglutathione Lyase/metabolism ; Mice ; NF-kappa B/genetics ; NIH 3T3 Cells ; Signal Transduction ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/pathology ; Transcription Factor AP-1/genetics

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Skocz do pozycji: 3.

Tytuł:: MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas.
Autorzy:: Mukherjee M; Texas Children's Cancer Center, Department of Pediatric Hematology/Oncology, Houston, TX 77030.
Ge G; Texas Children's Cancer Center, Department of Pediatric Hematology/Oncology, Houston, TX 77030.
Zhang N; Texas Children's Cancer Center, Department of Pediatric Hematology/Oncology, Houston, TX 77030.
Edwards DG; Molecular and Cellular Biology; Baylor College of Medicine, Houston, TX 77030.
Sumazin P; Texas Children's Cancer Center, Department of Pediatric Hematology/Oncology, Houston, TX 77030.
Sharan SK; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702.
Rao PH; Texas Children's Cancer Center, Department of Pediatric Hematology/Oncology, Houston, TX 77030.
Medina D; Molecular and Cellular Biology; Baylor College of Medicine, Houston, TX 77030.
Pati D; Texas Children's Cancer Center, Department of Pediatric Hematology/Oncology, Houston, TX 77030.; Molecular and Cellular Biology; Baylor College of Medicine, Houston, TX 77030.; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2014 Nov 27; Vol. 33 (48), pp. 5511-5522. Date of Electronic Publication: 2013 Nov 25.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Adenocarcinoma/*genetics
Adenocarcinoma/*pathology
Mammary Neoplasms, Experimental/*genetics
Mammary Neoplasms, Experimental/*pathology
Separase/*genetics
Adenocarcinoma/metabolism ; Aneuploidy ; Animals ; Blotting, Western ; Comparative Genomic Hybridization ; Estrogen Receptor alpha/biosynthesis ; Female ; Fluorescent Antibody Technique ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Mammary Neoplasms, Experimental/metabolism ; Mammary Tumor Virus, Mouse ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Separase/metabolism

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Skocz do pozycji: 4.

Tytuł:: Array CGH demonstrates characteristic aberration signatures in human papillary thyroid carcinomas governed by RET/PTC.
Autorzy:: Unger, K.
Malisch, E.
Thomas, G.
Braselmann, H.
Walch, A.
Jackl, G.
Lewis, P.
Lengfelder, E.
Bogdanova, T.
Wienberg, J.
Zitzelsberger, H.; Pokaż więcej
Źródło:: Oncogene. 7/31/2008, Vol. 27 Issue 33, p4592-4602. 11p. 1 Diagram, 5 Charts, 4 Graphs.

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Skocz do pozycji: 5.

Tytuł:: High-resolution array CGH analysis of salivary gland tumors reveals fusion and amplification of the FGFR1 and PLAG1 genes in ring chromosomes.
Autorzy:: Persson, F.
Winnes, M.
Andrén, Y.
Wedell, B.
Dahlenfors, R.
Asp, J.
Mark, J.
Enlund, F.
Stenman, G.; Pokaż więcej
Źródło:: Oncogene. 5/8/2008, Vol. 27 Issue 21, p3072-3080. 9p. 1 Color Photograph, 1 Diagram, 1 Chart, 1 Graph.

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Skocz do pozycji: 6.

Tytuł:: ACTuDB, a new database for the integrated analysis of array-CGH and clinical data for tumors.
Autorzy:: Hupé, P.
La Rosa, P.
Liva, S.
Lair, S.
Servant, N.
Barillot, E.; Pokaż więcej
Źródło:: Oncogene. 10/11/2007, Vol. 26 Issue 46, p6641-6652. 12p. 7 Color Photographs, 2 Charts, 1 Graph.

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Skocz do pozycji: 7.

Tytuł:: Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-array.
Autorzy:: Nakaya, K.
Yamagata, H. D.
Arita, N.
Nakashiro, K.-i.
Nose, M.
Miki, T.
Hamakawa, H.; Pokaż więcej
Źródło:: Oncogene. 8/9/2007, Vol. 26 Issue 36, p5300-5308. 9p. 6 Black and White Photographs, 1 Diagram, 3 Charts, 1 Graph.

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Skocz do pozycji: 8.

Tytuł:: Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Autorzy:: Jönsson, G.
Dahl, C.
Staaf, J.
Sandberg, T.
Bendahl, P.-O.
Ringnér, M.
Guldberg, P.
Borg, Å.; Pokaż więcej
Źródło:: Oncogene. 7/12/2007, Vol. 26 Issue 32, p4738-4748. 11p. 1 Color Photograph, 2 Charts, 3 Graphs.

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Skocz do pozycji: 9.

Tytuł:: Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers.
Autorzy:: Chin, S.-F.
Wang, Y.
Thorne, N. P.
Teschendorff, A. E.
Pinder, S. E.
Vias, M.
Naderi, A.
Roberts, I.
Barbosa-Morais, N. L.
Garcia, M. J.
Iyer, N. G.
Kranjac, T.
Robertson, J. F. R.
Aparicio, S.
Tavaré, S.
Ellis, I.
Brenton, J. D.
Caldas, C.; Pokaż więcej
Źródło:: Oncogene. 3/22/2007, Vol. 26 Issue 13, p1959-1970. 12p. 2 Charts, 4 Graphs.

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Skocz do pozycji: 10.

Tytuł:: RGC32, a novel p53-inducible gene, is located on centrosomes during mitosis and results in G2/M arrest.
Autorzy:: Saigusa, K.
Imoto, I.
Tanikawa, C.
Aoyagi, M.
Ohno, K.
Nakamura, Y.
Inazawa, J.; Pokaż więcej
Źródło:: Oncogene. 2/22/2007, Vol. 26 Issue 8, p1110-1121. 12p.

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Skocz do pozycji: 11.

Tytuł:: Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays.
Autorzy:: Clark, Jeremy
Edwards, Sandra
Feber, Andrew
Flohr, Penny
John, Megan
Giddings, Ian
Crossland, Sue
Stratton, Michael R
Wooster, Richard
Campbell, Colin
Cooper, Colin S; Pokaż więcej
Źródło:: Oncogene. 2/27/2003, Vol. 22 Issue 8, p1247. 6p.

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Skocz do pozycji: 12.

Tytuł:: Combined LOH/CGH analysis proves the existence of interstitial 3p deletions in renal cell carcinoma.
Autorzy:: Alimov, Andrei
Kost-Alimova, Maria
Liu, Jian
Li, Chunde
Bergerheim, Ulf
Imreh, Stefan
Klein, George
Zabarovsky, Eugene R; Pokaż więcej
Źródło:: Oncogene. 3/9/2000, Vol. 19 Issue 11, p1392. 8p.

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Skocz do pozycji: 13.

Tytuł:: Flotillin-2 deficiency leads to reduced lung metastases in a mouse breast cancer model.
Autorzy:: Berger T; The Campbell Family Institute for Breast Cancer Research, University Health Network, Toronto, ON, Canada.
Ueda T
Arpaia E
Chio II
Shirdel EA
Jurisica I
Hamada K
You-Ten A
Haight J
Wakeham A
Cheung CC
Mak TW; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2013 Oct 10; Vol. 32 (41), pp. 4989-94. Date of Electronic Publication: 2012 Nov 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Lung Neoplasms/*genetics
Lung Neoplasms/*secondary
Mammary Neoplasms, Experimental/*pathology
Membrane Proteins/*deficiency
Membrane Proteins/*genetics
Animals ; Cell Line, Tumor ; Cell Transformation, Neoplastic ; Comparative Genomic Hybridization ; Disease Models, Animal ; Female ; Gene Silencing ; Humans ; Mice

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Skocz do pozycji: 14.

Tytuł:: Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic myeloid leukemias.
Autorzy:: Tobin LA; Department of Radiation Oncology, Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Robert C
Rapoport AP
Gojo I
Baer MR
Tomkinson AE
Rassool FV; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2013 Apr 04; Vol. 32 (14), pp. 1784-93. Date of Electronic Publication: 2012 May 28.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Poly(ADP-ribose) Polymerase Inhibitors*
Benzamides/*pharmacology
DNA Breaks, Double-Stranded/*drug effects
DNA End-Joining Repair/*drug effects
DNA Ligases/*antagonists & inhibitors
Drug Resistance, Neoplasm/*drug effects
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Piperazines/*pharmacology
Pyrimidines/*pharmacology
Antineoplastic Combined Chemotherapy Protocols ; Apoptosis/drug effects ; Blotting, Western ; Cell Proliferation/drug effects ; Comparative Genomic Hybridization ; DNA Ligase ATP ; DNA Ligases/genetics ; DNA Ligases/metabolism ; Enzyme Inhibitors/pharmacology ; Fluorescent Antibody Technique ; Fusion Proteins, bcr-abl/metabolism ; Humans ; Imatinib Mesylate ; Immunoenzyme Techniques ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Poly (ADP-Ribose) Polymerase-1 ; Poly(ADP-ribose) Polymerases/genetics ; Poly(ADP-ribose) Polymerases/metabolism ; Poly-ADP-Ribose Binding Proteins ; Protein Kinase Inhibitors/pharmacology ; RNA, Messenger/genetics ; RNA, Small Interfering/genetics ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Cells, Cultured ; Xenopus Proteins

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Skocz do pozycji: 15.

Tytuł:: Comparative genomic hybridisation of ductal carcinoma in situ of the breast: identification of regions of DNA amplification and deletion in common with invasive breast carcinoma.
Autorzy:: James, L A
Mitchell, E L D
Menasce, L
Varley, J M; Pokaż więcej
Źródło:: Oncogene. 3/6/97, Vol. 14 Issue 9, p1059. 7p.

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Skocz do pozycji: 16.

Tytuł:: Recurrent deletion of CHD1 in prostate cancer with relevance to cell invasiveness.
Autorzy:: Huang S; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305-5176, USA.
Gulzar ZG
Salari K
Lapointe J
Brooks JD
Pollack JR; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2012 Sep 13; Vol. 31 (37), pp. 4164-70. Date of Electronic Publication: 2011 Dec 19.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Sequence Deletion*
DNA Helicases/*genetics
DNA-Binding Proteins/*genetics
Prostatic Neoplasms/*genetics
Cell Line, Tumor ; Cell Proliferation ; Cell Transformation, Neoplastic/genetics ; Chromatin Assembly and Disassembly ; Comparative Genomic Hybridization ; DNA Helicases/biosynthesis ; DNA-Binding Proteins/biosynthesis ; Gene Expression Profiling ; Humans ; Male ; Neoplasm Invasiveness/genetics ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; RNA Interference ; RNA, Small Interfering

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Skocz do pozycji: 17.

Tytuł:: Mcm2 deficiency results in short deletions allowing high resolution identification of genes contributing to lymphoblastic lymphoma.
Autorzy:: Rusiniak ME; Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
Kunnev D
Freeland A
Cady GK
Pruitt SC; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2012 Sep 06; Vol. 31 (36), pp. 4034-44. Date of Electronic Publication: 2011 Dec 12.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genes, Neoplasm*
Sequence Deletion*
Cell Cycle Proteins/*deficiency
Nuclear Proteins/*deficiency
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Thymus Neoplasms/*genetics
Animals ; Base Sequence ; Cell Cycle Proteins/genetics ; Chromosome Breakpoints ; Chromosomes, Mammalian/genetics ; Comparative Genomic Hybridization ; DNA Copy Number Variations ; Humans ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Minichromosome Maintenance Complex Component 2 ; Molecular Sequence Data ; Nuclear Proteins/genetics ; Sequence Analysis, DNA

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Skocz do pozycji: 18.

Tytuł:: The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas.
Autorzy:: Li L; Cancer Epigenetics Laboratory, Department of Clinical Oncology, State Key Laboratory of Oncology in South China, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong and CUHK Shenzhen Research Institute, Hong Kong.
Ying J
Li H
Zhang Y
Shu X
Fan Y
Tan J
Cao Y
Tsao SW
Srivastava G
Chan AT
Tao Q; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2012 Aug 23; Vol. 31 (34), pp. 3901-12. Date of Electronic Publication: 2011 Dec 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Signal Transduction*
Cadherins/*metabolism
Tumor Suppressor Proteins/*metabolism
Wnt Proteins/*metabolism
beta Catenin/*metabolism
Apoptosis/genetics ; Blotting, Western ; Cadherins/genetics ; Cell Line ; Cell Line, Tumor ; Cell Membrane/metabolism ; Chromosomes, Human, Pair 16/genetics ; Comparative Genomic Hybridization/methods ; CpG Islands/genetics ; DNA Methylation ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; HCT116 Cells ; Humans ; Microscopy, Confocal ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Promoter Regions, Genetic/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Suppressor Proteins/genetics

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Skocz do pozycji: 19.

Tytuł:: Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma.
Autorzy:: Santo EE; Department of Oncogenomics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Ebus ME
Koster J
Schulte JH
Lakeman A
van Sluis P
Vermeulen J
Gisselsson D
Øra I
Lindner S
Buckley PG
Stallings RL
Vandesompele J
Eggert A
Caron HN
Versteeg R
Molenaar JJ; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2012 Mar 22; Vol. 31 (12), pp. 1571-81. Date of Electronic Publication: 2011 Aug 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Chromosomes, Human, Pair 11*
Recombination, Genetic*
Neuroblastoma/*genetics
Animals ; Cell Line, Tumor ; Comparative Genomic Hybridization ; Gene Expression Regulation, Neoplastic ; Gene Silencing ; Haploinsufficiency ; Humans ; Loss of Heterozygosity ; Mice ; Oncogene Fusion ; Polymorphism, Single Nucleotide ; Sequence Deletion

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Skocz do pozycji: 20.

Tytuł:: Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXT.
Autorzy:: de Andrea CE; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Reijnders CM
Kroon HM
de Jong D
Hogendoorn PC
Szuhai K
Bovée JV; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2012 Mar 01; Vol. 31 (9), pp. 1095-104. Date of Electronic Publication: 2011 Aug 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bone Neoplasms/*genetics
Bone Neoplasms/*pathology
Chondrosarcoma/*genetics
N-Acetylglucosaminyltransferases/*genetics
Neoplasms, Second Primary/*genetics
Osteochondroma/*pathology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Bone Neoplasms/metabolism ; Child ; Chondrosarcoma/metabolism ; Chondrosarcoma/pathology ; Chromosomes, Human, Pair 8 ; Comparative Genomic Hybridization ; Gene Deletion ; Homozygote ; Humans ; Middle Aged ; N-Acetylglucosaminyltransferases/metabolism ; Neoplasms, Second Primary/metabolism ; Neoplasms, Second Primary/pathology ; Osteochondroma/genetics ; Osteochondroma/metabolism ; Young Adult

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Skocz do pozycji: 21.

Tytuł:: Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours.
Autorzy:: Rajan N; Institute of Human Genetics, University of Newcastle upon Tyne, Newcastle upon Tyne, UK. />Elliott R
Clewes O
Mackay A
Reis-Filho JS
Burn J
Langtry J
Sieber-Blum M
Lord CJ
Ashworth A; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2011 Oct 13; Vol. 30 (41), pp. 4243-60. Date of Electronic Publication: 2011 May 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Neoplasms/*genetics
Protein Kinases/*genetics
Signal Transduction/*genetics
Tumor Suppressor Proteins/*genetics
Adenoma, Sweat Gland/genetics ; Adenoma, Sweat Gland/metabolism ; Adenoma, Sweat Gland/pathology ; Carbazoles/pharmacology ; Carcinoma, Adenoid Cystic/genetics ; Carcinoma, Adenoid Cystic/metabolism ; Carcinoma, Adenoid Cystic/pathology ; Cluster Analysis ; Comparative Genomic Hybridization ; Deubiquitinating Enzyme CYLD ; Furans ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Immunoblotting ; Immunohistochemistry ; Mutation ; Neoplasms/metabolism ; Neoplasms/pathology ; Neoplasms, Basal Cell/genetics ; Neoplasms, Basal Cell/metabolism ; Neoplasms, Basal Cell/pathology ; Oligonucleotide Array Sequence Analysis ; Primary Cell Culture ; Protein Kinases/metabolism ; RNA Interference ; Receptor, trkB/antagonists & inhibitors ; Receptor, trkB/genetics ; Receptor, trkB/metabolism ; Receptor, trkC/antagonists & inhibitors ; Receptor, trkC/genetics ; Receptor, trkC/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Sweat Gland Neoplasms/genetics ; Sweat Gland Neoplasms/metabolism ; Sweat Gland Neoplasms/pathology ; Tissue Array Analysis ; Tumor Cells, Cultured ; Tumor Suppressor Proteins/metabolism

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Skocz do pozycji: 22.

Tytuł:: Shared acquired genomic changes in zebrafish and human T-ALL.
Autorzy:: Rudner LA; Department of Oncological Sciences, Huntsman Cancer Institute, Salt Lake City, UT 84112, USA.
Brown KH
Dobrinski KP
Bradley DF
Garcia MI
Smith AC
Downie JM
Meeker ND
Look AT
Downing JR
Gutierrez A
Mullighan CG
Schiffman JD
Lee C
Trede NS
Frazer JK; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2011 Oct 13; Vol. 30 (41), pp. 4289-96. Date of Electronic Publication: 2011 May 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Comparative Genomic Hybridization/*methods
Genomics/*methods
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Zebrafish/*genetics
Animals ; Gene Expression Regulation, Neoplastic ; Genome/genetics ; Humans ; Kaplan-Meier Estimate ; Neoplasm Transplantation ; Transplantation, Heterologous

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Skocz do pozycji: 23.

Tytuł:: DNA copy number aberrations in small-cell lung cancer reveal activation of the focal adhesion pathway.
Autorzy:: Ocak S; Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University, Nashville, TN 37232-6838, USA.
Yamashita H
Udyavar AR
Miller AN
Gonzalez AL
Zou Y
Jiang A
Yi Y
Shyr Y
Estrada L
Quaranta V
Massion PP; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2010 Dec 02; Vol. 29 (48), pp. 6331-42. Date of Electronic Publication: 2010 Aug 30.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Focal Adhesions*
Gene Dosage*
Carcinoma, Small Cell/*genetics
Lung Neoplasms/*genetics
Carcinoma, Small Cell/pathology ; Cell Adhesion ; Cell Line, Tumor ; Comparative Genomic Hybridization ; Focal Adhesion Protein-Tyrosine Kinases/analysis ; Focal Adhesion Protein-Tyrosine Kinases/antagonists & inhibitors ; Focal Adhesion Protein-Tyrosine Kinases/physiology ; Humans ; Lung Neoplasms/pathology ; Quinolones/pharmacology ; Sulfones/pharmacology

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Skocz do pozycji: 24.

Tytuł:: Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency.
Autorzy:: Cheng L; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853-6401, USA.
Zhou Z
Flesken-Nikitin A
Toshkov IA
Wang W
Camps J
Ried T
Nikitin AY; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2010 Oct 21; Vol. 29 (42), pp. 5700-11. Date of Electronic Publication: 2010 Aug 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Adaptor Proteins, Signal Transducing/*genetics
Inhibitor of Apoptosis Proteins/*genetics
Mammary Neoplasms, Experimental/*genetics
Phosphoproteins/*genetics
Retinoblastoma Protein/*genetics
Tumor Suppressor Protein p53/*genetics
Animals ; Baculoviral IAP Repeat-Containing 3 Protein ; Cell Cycle Proteins ; Cell Transformation, Neoplastic/genetics ; Comparative Genomic Hybridization ; Female ; Gene Amplification ; Genomic Instability ; Immunohistochemistry ; Mammary Neoplasms, Experimental/pathology ; Mice ; Mice, Transgenic ; Tumor Suppressor Protein p53/deficiency ; Ubiquitin-Protein Ligases ; YAP-Signaling Proteins

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Skocz do pozycji: 25.

Tytuł:: Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion.
Autorzy:: Lau KM; Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong. />Chan QK
Pang JC
Li KK
Yeung WW
Chung NY
Lui PC
Tam YS
Li HM
Zhou L
Wang Y
Mao Y
Ng HK; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2010 Oct 07; Vol. 29 (40), pp. 5475-89. Date of Electronic Publication: 2010 Jul 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Cycle Proteins/*metabolism
Cell Movement/*genetics
DNA-Binding Proteins/*metabolism
Medulloblastoma/*metabolism
Nuclear Proteins/*metabolism
Biomarkers, Tumor/analysis ; Cell Cycle Proteins/genetics ; Cell Separation ; Cerebellar Neoplasms/genetics ; Cerebellar Neoplasms/metabolism ; Cerebellar Neoplasms/pathology ; Comparative Genomic Hybridization ; DNA-Binding Proteins/genetics ; Flow Cytometry ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Kaplan-Meier Estimate ; Medulloblastoma/genetics ; Medulloblastoma/pathology ; Minichromosome Maintenance Complex Component 2 ; Minichromosome Maintenance Complex Component 3 ; Minichromosome Maintenance Complex Component 7 ; Neoplasm Invasiveness/genetics ; Nuclear Proteins/genetics ; Oligonucleotide Array Sequence Analysis ; Prognosis ; Reverse Transcriptase Polymerase Chain Reaction

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Skocz do pozycji: 26.

Tytuł:: Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma.
Autorzy:: Cooke SL; Cancer Research UK Cambridge Research Institute, Li Ka Shing Center, Cambridge, UK.
Ng CK
Melnyk N
Garcia MJ
Hardcastle T
Temple J
Langdon S
Huntsman D
Brenton JD; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2010 Sep 02; Vol. 29 (35), pp. 4905-13. Date of Electronic Publication: 2010 Jun 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Evolution, Molecular*
Genetic Heterogeneity*
Genomics/*methods
Ovarian Neoplasms/*genetics
Ovarian Neoplasms/*pathology
Animals ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/genetics ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Comparative Genomic Hybridization ; Drug Resistance, Neoplasm/genetics ; Female ; Humans ; In Situ Hybridization, Fluorescence ; Neoplasm Staging ; Oligonucleotide Array Sequence Analysis ; Ovarian Neoplasms/drug therapy ; Time Factors

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Skocz do pozycji: 27.

Tytuł:: Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets.
Autorzy:: Turner N; The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, UK. />Lambros MB
Horlings HM
Pearson A
Sharpe R
Natrajan R
Geyer FC
van Kouwenhove M
Kreike B
Mackay A
Ashworth A
van de Vijver MJ
Reis-Filho JS; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2010 Apr 08; Vol. 29 (14), pp. 2013-23. Date of Electronic Publication: 2010 Jan 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Amplification*
Gene Expression Regulation, Neoplastic*
Breast Neoplasms/*drug therapy
Breast Neoplasms/*metabolism
Animals ; Apoptosis ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Survival ; Comparative Genomic Hybridization ; Gene Dosage/genetics ; Gene Expression Profiling ; Genomics ; Humans ; Ligands ; Phosphatidylinositol 3-Kinases/metabolism ; Receptor Protein-Tyrosine Kinases/metabolism ; Receptor, Fibroblast Growth Factor, Type 2/genetics ; Reproducibility of Results ; Signal Transduction

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Skocz do pozycji: 28.

Tytuł:: Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer.
Autorzy:: Kim YH; Department of Pathology, Stanford University, Stanford, CA 94305-5176, USA.
Kwei KA
Girard L
Salari K
Kao J
Pacyna-Gengelbach M
Wang P
Hernandez-Boussard T
Gazdar AF
Petersen I
Minna JD
Pollack JR; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2010 Mar 11; Vol. 29 (10), pp. 1421-30. Date of Electronic Publication: 2009 Dec 07.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Gene Amplification*
Gene Expression Profiling*
Adaptor Proteins, Signal Transducing/*genetics
Lung Neoplasms/*genetics
Nuclear Proteins/*genetics
Adaptor Proteins, Signal Transducing/metabolism ; Adaptor Proteins, Signal Transducing/physiology ; Blotting, Western ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Carcinoma, Non-Small-Cell Lung/physiopathology ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cell Survival ; Chromosomes, Human, Pair 22/genetics ; Comparative Genomic Hybridization ; Humans ; In Situ Hybridization, Fluorescence ; Lung Neoplasms/pathology ; Lung Neoplasms/physiopathology ; Nuclear Proteins/metabolism ; Nuclear Proteins/physiology ; Oligonucleotide Array Sequence Analysis ; RNA Interference

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Skocz do pozycji: 29.

Tytuł:: Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling.
Autorzy:: Beck AH; Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA.
Lee CH
Witten DM
Gleason BC
Edris B
Espinosa I
Zhu S
Li R
Montgomery KD
Marinelli RJ
Tibshirani R
Hastie T
Jablons DM
Rubin BP
Fletcher CD
West RB
van de Rijn M; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2010 Feb 11; Vol. 29 (6), pp. 845-54. Date of Electronic Publication: 2009 Nov 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Profiling*
Leiomyosarcoma/*classification
Leiomyosarcoma/*genetics
Biomarkers, Tumor/metabolism ; Comparative Genomic Hybridization ; Genomics ; Humans ; Immunohistochemistry ; Leiomyosarcoma/diagnosis ; Leiomyosarcoma/metabolism ; Prognosis ; Tissue Array Analysis

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Skocz do pozycji: 30.

Tytuł:: Focal amplification and oncogene dependency of GAB2 in breast cancer.
Autorzy:: Bocanegra M; Department of Pathology, Stanford University, Stanford, CA 94305-5176, USA.
Bergamaschi A
Kim YH
Miller MA
Rajput AB
Kao J
Langerød A
Han W
Noh DY
Jeffrey SS
Huntsman DG
Børresen-Dale AL
Pollack JR; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2010 Feb 04; Vol. 29 (5), pp. 774-9. Date of Electronic Publication: 2009 Nov 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Amplification*
Adaptor Proteins, Signal Transducing/*genetics
Breast Neoplasms/*genetics
Signal Transduction/*physiology
Cell Proliferation ; Cell Survival/physiology ; Comparative Genomic Hybridization ; Female ; Gene Expression Profiling ; Humans ; In Situ Hybridization, Fluorescence ; Oligonucleotide Array Sequence Analysis ; Oncogenes

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Skocz do pozycji: 31.

Tytuł:: Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma.
Autorzy:: Jones DT; Department of Pathology, Division of Molecular Histopathology, University of Cambridge, Cambridge, Cambridgeshire, UK. />Kocialkowski S
Liu L
Pearson DM
Ichimura K
Collins VP; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2009 May 21; Vol. 28 (20), pp. 2119-23. Date of Electronic Publication: 2009 Apr 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Rearrangement*
Astrocytoma/*genetics
MAP Kinase Signaling System/*physiology
Mutation/*genetics
Oncogene Proteins, Fusion/*genetics
Proto-Oncogene Proteins B-raf/*genetics
Proto-Oncogene Proteins c-raf/*genetics
Animals ; Astrocytoma/metabolism ; Astrocytoma/pathology ; Comparative Genomic Hybridization ; GTPase-Activating Proteins/genetics ; GTPase-Activating Proteins/metabolism ; Humans ; Mice ; NIH 3T3 Cells ; Oligonucleotide Array Sequence Analysis ; Oncogene Proteins, Fusion/metabolism ; Proto-Oncogene Proteins B-raf/metabolism ; Proto-Oncogene Proteins c-raf/metabolism

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Skocz do pozycji: 32.

Tytuł:: Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis.
Autorzy:: Kwek SS; Cancer Research Institute, University of California San Francisco, San Francisco, CA 94143-0808, USA.
Roy R
Zhou H
Climent J
Martinez-Climent JA
Fridlyand J
Albertson DG; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2009 Apr 30; Vol. 28 (17), pp. 1892-903. Date of Electronic Publication: 2009 Mar 30.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Gene Amplification*
Breast Neoplasms/*genetics
Chromosomes, Human, Pair 11/*genetics
Chromosomes, Human, Pair 8/*genetics
Oncogenes/*genetics
Breast Neoplasms/pathology ; Carrier Proteins/genetics ; Cell Line, Tumor ; Comparative Genomic Hybridization ; Cyclin D1/genetics ; Epistasis, Genetic ; Female ; Gene Dosage ; Gene Expression Regulation, Neoplastic ; Genetic Predisposition to Disease ; Humans ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Oncogene Protein p55(v-myc)/genetics ; Phospholipases/genetics ; RNA, Small Interfering/genetics ; Receptor, Fibroblast Growth Factor, Type 1/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction/genetics ; Transfection ; Tumor Suppressor Protein p53/genetics

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Skocz do pozycji: 33.

Tytuł:: Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies
Autorzy:: Shiu, K-K
Wetterskog, D
Mackay, A
Natrajan, R
Lambros, M
Sims, D
Bajrami, I
Brough, R
Frankum, J
Sharpe, R
Marchio, C
Horlings, H
Reyal, F
van der Vijver, M
Turner, N
Reis-Filho, J SAff1, IDonc2012625_cor16
Lord, C JAff1, IDonc2012625_cor17
Ashworth, AAff1, IDonc2012625_cor18; Pokaż więcej
Źródło:: Oncogene. 33(5):619-631

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Skocz do pozycji: 34.

Tytuł:: An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors.
Autorzy:: Chitale, D.
Gong, Y.
Taylor, B. S.
Broderick, S.
Brennan, C.
Somwar, R.
Golas, B.
Wang, L.
Motoi, N.
Szoke, J.
Reinersman, J. M.
Major, J.
Sander, C.
Seshan, V. E.
Zakowski, M. F.
Rusch, V.
Pao, W.
Gerald, W.
Ladanyi, M.; Pokaż więcej
Źródło:: Oncogene. 8/6/2009, Vol. 28 Issue 31, p2773-2783. 11p. 1 Chart, 6 Graphs.

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Skocz do pozycji: 35.

Tytuł:: PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation.
Autorzy:: Suzuki, E.
Imoto, I.
Pimkhaokham, A.
Nakagawa, T.
Kamata, N.
Kozaki, K.-i
Amagasa, T.
Inazawa, J.; Pokaż więcej
Źródło:: Oncogene. 12/13/2007, Vol. 26 Issue 57, p7921-7932. 12p. 3 Black and White Photographs, 3 Charts, 2 Graphs.

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Skocz do pozycji: 36.

Tytuł:: Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization.
Autorzy:: Strefford, J. C.
Worley, H.
Barber, K.
Wright, S.
Stewart, A. R. M.
Robinson, H. M.
Bettney, G.
van Delft, F. W.
Atherton, M. G.
Davies, T.
Griffiths, M.
Hing, S.
Ross, F. M.
Talley, P.
Saha, V.
Moorman, A. V.
Harrison, C. J.; Pokaż więcej
Źródło:: Oncogene. 6/21/2007, Vol. 26 Issue 29, p4306-4318. 13p. 3 Diagrams, 2 Charts.

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Skocz do pozycji: 37.

Tytuł:: A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH.
Autorzy:: Roylance, R.
Gorman, P.
Papior, T.
Wan, Y-L.
Ives, M.
Watson, J. E.
Collins, C.
Wortham, N.
Langford, C.
Fiegler, H.
Carter, N.
Gillett, C.
Sasieni, P.
Pinder, S.
Hanby, A.
Tomlinson, I.; Pokaż więcej
Źródło:: Oncogene. 10/19/2006, Vol. 25 Issue 49, p6544-6553. 10p. 2 Charts, 6 Graphs.

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Skocz do pozycji: 38.

Tytuł:: Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer.
Autorzy:: Bastian, Boris C; Pokaż więcej
Źródło:: Oncogene. 5/19/2003 Review, Vol. 22 Issue 20, p3081-3086. 6p.

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Skocz do pozycji: 39.

Tytuł:: Genomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome.
Autorzy:: Pal, J
Bertheau, R
Buon, L
Qazi, A
Batchu, R B
Bandyopadhyay, S
Ali-Fehmi, R
Beer, D G
Weaver, D W
Shmookler Reis, R J
Goyal, R K
Huang, Q
Munshi, N C
Shammas, M A; Pokaż więcej
Temat:: BARRETT'S esophagus
CANCER genetics
GENETIC recombination research
GENETIC regulation
CELL proliferation
MOLECULAR evolution
DISEASE progression
CONTINUOUS cell lines
COMPARATIVE genomic hybridization
THERAPEUTICS
Źródło:: Oncogene; 8/18/2011, Vol. 30 Issue 33, p3585-3598, 14p

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Skocz do pozycji: 40.

Tytuł:: Epigenetic disruption of interferon-γ response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas.
Autorzy:: Lee, K. Y.
Geng, H.
Ng, K. M.
Yu, J.
van Hasselt, A.
Cao, Y.
Zeng, Y.-X.
Wong, A. H. Y.
Wang, X.
Ying, J.
Srivastava, G.
Lung, M. L.
Wang, L.-D.
Kwok, T. T.
Levi, B.-Z.
Chan, A. T. C.
Sung, J. J. Y.
Tao, Q.; Pokaż więcej
Temat:: CANCER cells
INTERFERONS
GENETIC regulation
COMPARATIVE genomic hybridization
ESOPHAGEAL cancer
MALE reproductive organs
Źródło:: Oncogene; 9/4/2008, Vol. 27 Issue 39, p5267-5276, 10p, 2 Black and White Photographs, 4 Diagrams, 1 Chart, 1 Graph

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Skocz do pozycji: 41.

Tytuł:: In neuroblastic tumours, Schwann cells do not harbour the genetic alterations of neuroblasts but may nevertheless share the same clonal origin.
Autorzy:: Bourdeaut, F.
Ribeiro, A.
Paris, R.
Pierron, G.
Couturier, J.
Peuchmaur, M.
Delattre, O.; Pokaż więcej
Temat:: NEUROBLASTOMA
NERVOUS system tumors
CANCER cells
CHROMOSOMES
COMPARATIVE genomic hybridization
ONCOLOGY
Źródło:: Oncogene; 5/8/2008, Vol. 27 Issue 21, p3066-3071, 6p, 1 Color Photograph, 1 Diagram, 1 Chart, 3 Graphs

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Skocz do pozycji: 42.

Tytuł:: Array CGH and gene-expression profiling reveals distinct genomic instability patterns associated with DNA repair and cell-cycle checkpoint pathways in Ewing's sarcoma.
Autorzy:: Ferreira, B I
Alonso, J
Carrillo, J
Acquadro, F
Largo, C
Suela, J
Teixeira, M R
Cerveira, N
Molares, A
Goméz-López, G
Pestaña, Á
Sastre, A
Garcia-Miguel, P
Cigudosa, J C; Pokaż więcej
Temat:: DNA repair
EWING'S sarcoma
CELL cycle
COMPARATIVE genomic hybridization
GENE expression
TUMORS
Źródło:: Oncogene; 3/27/2008, Vol. 27 Issue 14, p2084-2090, 7p, 2 Charts, 4 Graphs

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Skocz do pozycji: 43.

Tytuł:: POU2AF1, an amplification target at 11q23, promotes growth of multiple myeloma cells by directly regulating expression of a B-cell maturation factor, TNFRSF17.
Autorzy:: Zhao, C.
Inoue, J.
Imoto, I.
Otsuki, T.
Iida, S.
Ueda, R.
Inazawa, J.; Pokaż więcej
Temat:: TUMOR growth
MULTIPLE myeloma
GROWTH
COMPARATIVE genomic hybridization
BREEDING
Źródło:: Oncogene; 1/3/2008, Vol. 27 Issue 1, p63-75, 13p, 1 Chart, 5 Graphs