Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Ukraiński (UK)
Przejdź do strony domowej biblioteki Uniwersytet Ekonomiczny we Wrocławiu Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

Wyszukujesz frazę ""Complement C3a"" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-20 z 285
Tytuł:
SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling.
Autorzy:
Perico L; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy. .
Morigi M; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Pezzotta A; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Locatelli M; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Imberti B; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Corna D; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Cerullo D; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Benigni A; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Remuzzi G; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2023 Jul 14; Vol. 13 (1), pp. 11392. Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Spike Glycoprotein, Coronavirus*
Endothelial Cells*/cytology
Endothelial Cells*/virology
Complement C3a*/metabolism
Receptors, Complement*/metabolism
SARS-CoV-2 ; Lung/pathology ; Lung/virology ; Fibrosis ; Mice, Transgenic ; Humans ; Animals ; Mice ; COVID-19 ; Inflammation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Potential Role of Complement System in the Progression of Ovarian Clear Cell Carcinoma Inferred from the Gene Ontology-Based Immunofunctionome Analysis.
Autorzy:
Su KM; Department of Obstetrics and Gynecology, Tri-service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.
Lin TW; Department of Medical Research, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Liu LC; Department of Obstetrics and Gynecology, Tri-service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.; Division of Obstetrics and Gynecology, Tri-Service General Hospital Songshan Branch, National Defense Medical Center, Taipei 105, Taiwan.
Yang YP; Department of Medical Research, Taipei Veterans General Hospital, Taipei 112, Taiwan.; School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.
Wang ML; Department of Medical Research, Taipei Veterans General Hospital, Taipei 112, Taiwan.; School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.
Tsai PH; Department of Medical Research, Taipei Veterans General Hospital, Taipei 112, Taiwan.; School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.
Wang PH; School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.; Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei 112, Taiwan.; Department of Medical Research, China Medical University Hospital, Taichung 404, Taiwan.
Yu MH; Department of Obstetrics and Gynecology, Tri-service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.
Chang CM; School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.; Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Chang CC; Department of Obstetrics and Gynecology, Tri-service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Apr 17; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 17.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma, Clear Cell/*genetics
Complement C3a/*genetics
Gene Expression Profiling/*methods
Ovarian Neoplasms/*genetics
Receptors, Complement/*genetics
Adenocarcinoma, Clear Cell/immunology ; Adenocarcinoma, Clear Cell/mortality ; Case-Control Studies ; Complement C3a/metabolism ; Disease Progression ; Female ; Gene Expression Regulation, Neoplastic ; Gene Ontology ; Humans ; Machine Learning ; Oligonucleotide Array Sequence Analysis ; Ovarian Neoplasms/immunology ; Ovarian Neoplasms/mortality ; Receptors, Complement/metabolism ; Survival Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Complement C3a activates astrocytes to promote medulloblastoma progression through TNF-α.
Autorzy:
Gong B; Laboratory of Molecular Neuropathology, Pediatric Cancer Center, College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Guo D; Laboratory of Molecular Neuropathology, Pediatric Cancer Center, College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Zheng C; Laboratory of Molecular Neuropathology, Pediatric Cancer Center, College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Ma Z; Laboratory of Molecular Neuropathology, Pediatric Cancer Center, College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Zhang J; Laboratory of Molecular Neuropathology, Pediatric Cancer Center, College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Qu Y; Laboratory of Molecular Neuropathology, Pediatric Cancer Center, College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Li X; Laboratory of Molecular Neuropathology, Pediatric Cancer Center, College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Li G; Laboratory of Molecular Neuropathology, Pediatric Cancer Center, College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Zhang L; Laboratory of Molecular Neuropathology, Pediatric Cancer Center, College of Pharmaceutical Sciences, Soochow University, Suzhou, China. .
Wang Y; Laboratory of Molecular Neuropathology, Pediatric Cancer Center, College of Pharmaceutical Sciences, Soochow University, Suzhou, China. .
Pokaż więcej
Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2022 Jun 20; Vol. 19 (1), pp. 159. Date of Electronic Publication: 2022 Jun 20.
Typ publikacji:
Journal Article
MeSH Terms:
Cerebellar Neoplasms*/metabolism
Cerebellar Neoplasms*/pathology
Medulloblastoma*/metabolism
Medulloblastoma*/pathology
Animals ; Astrocytes/metabolism ; Cells, Cultured ; Complement C3a ; Humans ; Mice ; Tumor Microenvironment ; Tumor Necrosis Factor-alpha/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Brief report on the relation between complement C3a and anti dsDNA antibody in systemic lupus erythematosus.
Autorzy:
Cai YH; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China.
Deng J; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China.; Hubei Clinical and Research Center of Thrombosis and Hemostasis, Wuhan, Hubei, China.
Chen ZL; Institute of Hematology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Mei H; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China.; Hubei Clinical and Research Center of Thrombosis and Hemostasis, Wuhan, Hubei, China.
Tang L; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China.; Hubei Clinical and Research Center of Thrombosis and Hemostasis, Wuhan, Hubei, China.
Luo SS; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China. .
Hu Y; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China. dr_.; Hubei Clinical and Research Center of Thrombosis and Hemostasis, Wuhan, Hubei, China. dr_.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 May 02; Vol. 12 (1), pp. 7098. Date of Electronic Publication: 2022 May 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Complement C1q*
Lupus Erythematosus, Systemic*
Antibodies, Antinuclear ; Autoantibodies ; Complement C3a ; DNA ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The anti-C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID-19.
Autorzy:
Vlaar APJ; Department of Intensive Care, University of Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
Lim EHT; Department of Intensive Care, University of Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Neurology, University of Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, The Netherlands.
de Bruin S; Department of Intensive Care, University of Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
Rückinger S; Metronomia Clinical Research GmbH, Munich, Germany.
Pilz K; InflaRx GmbH, Jena, Germany.
Brouwer MC; Department of Neurology, University of Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, The Netherlands.
Guo RF; InflaRx Pharmaceuticals Inc., Ann Arbor, Michigan, USA.
Heunks LMA; Department of Intensive Care, VU Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
Busch MH; Department of Immunology, Maastricht UMC+, Maastricht, The Netherlands.
van Paassen P; Department of Immunology, Maastricht UMC+, Maastricht, The Netherlands.
Riedemann NC; InflaRx GmbH, Jena, Germany.
van de Beek D; Department of Neurology, University of Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, The Netherlands.
Pokaż więcej
Źródło:
Clinical and translational science [Clin Transl Sci] 2022 Apr; Vol. 15 (4), pp. 854-858. Date of Electronic Publication: 2022 Jan 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Monoclonal*/pharmacology
Antibodies, Monoclonal*/therapeutic use
COVID-19 Drug Treatment*
Clinical Trials, Phase II as Topic ; Complement C3a ; Complement C5a ; Humans ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Excretions/secretions from medicinal larvae (Lucilia sericata) inhibit complement activation by two mechanisms.
Autorzy:
Tamura T; Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Cazander G; Department of Surgery, Medical Center Haaglanden/Bronovo Hospital, The Hague, the Netherlands.
Rooijakkers SH; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Trouw LA; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
Nibbering PH; Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.
Pokaż więcej
Źródło:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society [Wound Repair Regen] 2017 Jan; Vol. 25 (1), pp. 41-50. Date of Electronic Publication: 2017 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Complement C3a/*antagonists & inhibitors
Complement C5a/*antagonists & inhibitors
Diptera/*metabolism
Inflammation/*physiopathology
Larva/*physiology
Wound Healing/*physiology
Animals ; Bodily Secretions/metabolism ; Complement Activation/physiology ; Complement C3a/metabolism ; Complement C5a/metabolism ; Debridement/methods ; Down-Regulation ; Inflammation/metabolism ; Neutrophil Activation/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
C3a Increases VEGF and Decreases PEDF mRNA Levels in Human Retinal Pigment Epithelial Cells.
Autorzy:
Long Q; Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Key Laboratory of Myopia, Ministry of Health, Fudan University, Shanghai, China.
Cao X; Department of Ophthalmology, People's Hospital of Peking University, Beijing, China.
Bian A; Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li Y; Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Pokaż więcej
Źródło:
BioMed research international [Biomed Res Int] 2016; Vol. 2016, pp. 6958752. Date of Electronic Publication: 2016 Sep 22.
Typ publikacji:
Journal Article
MeSH Terms:
Complement C3a/*pharmacology
Epithelial Cells/*metabolism
Eye Proteins/*genetics
Nerve Growth Factors/*genetics
Retinal Pigment Epithelium/*cytology
Serpins/*genetics
Vascular Endothelial Growth Factor A/*genetics
Cell Line ; Complement C3a/genetics ; Complement C3a/metabolism ; Epithelial Cells/drug effects ; Eye Proteins/metabolism ; Humans ; Nerve Growth Factors/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Serpins/metabolism ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
C3a and Its Receptor C3aR Are Detectable in Normal Human Epidermal Keratinocytes and Are Differentially Regulated via TLR3 and LL37.
Autorzy:
Mommert S; Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany, .
Doenni L; Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
Szudybill P; Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
Zoeller C; Department of Pediatric Surgery, Hannover Medical School, Hannover, Germany.
Beyer FH; Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
Werfel T; Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
Pokaż więcej
Źródło:
Journal of innate immunity [J Innate Immun] 2021; Vol. 13 (3), pp. 164-178. Date of Electronic Publication: 2021 Jan 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antimicrobial Cationic Peptides/*metabolism
Complement C3a/*metabolism
Epidermal Cells/*immunology
Keratinocytes/*immunology
Receptors, Complement/*metabolism
Toll-Like Receptor 3/*metabolism
Cathepsin L/metabolism ; Cells, Cultured ; Chemokine CXCL10/metabolism ; Complement Activation ; Flow Cytometry ; Gene Expression Regulation ; Humans ; Poly I-C/immunology ; Primary Cell Culture ; Cathelicidins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Complement component C3a plays a critical role in endothelial activation and leukocyte recruitment into the brain.
Autorzy:
Wu F; Department of Immunology, Nanjing Medical University, 140 Hanzhong Road, Nanjing, JS, 210029, China. .
Zou Q; Department of Immunology, Chengdu Medical College, Chengdu, 610083, Sichuan, China. .
Ding X; Department of Immunology, Nanjing Medical University, 140 Hanzhong Road, Nanjing, JS, 210029, China. .
Shi D; Department of Immunology, Nanjing Medical University, 140 Hanzhong Road, Nanjing, JS, 210029, China. .
Zhu X; Department of Immunology, Nanjing Medical University, 140 Hanzhong Road, Nanjing, JS, 210029, China. .
Hu W; Shanghai Cancer Center and Institute of Biomedical Science, Shanghai Medical College, Shanghai Cancer Center, Fudan University, Shanghai, 200032, China. .
Liu L; Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, S7N 5E5, Canada. .
Zhou H; Department of Immunology, Nanjing Medical University, 140 Hanzhong Road, Nanjing, JS, 210029, China. .
Pokaż więcej
Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2016 Jan 28; Vol. 13, pp. 23. Date of Electronic Publication: 2016 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Brain/*cytology
Complement C3a/*metabolism
Endothelial Cells/*physiology
Leukocytes/*physiology
Neutrophil Infiltration/*physiology
Animals ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/physiology ; Brain/drug effects ; Cell Adhesion/drug effects ; Cell Adhesion/genetics ; Cell Adhesion Molecules/genetics ; Cell Adhesion Molecules/metabolism ; Cells, Cultured ; Complement C3a/genetics ; Endothelial Cells/drug effects ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/genetics ; Injections, Intraventricular ; Leukocytes/drug effects ; Lipopolysaccharides/pharmacology ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Transgenic ; Microvessels/drug effects ; Microvessels/physiology ; NF-kappa B/metabolism ; Neutrophil Infiltration/drug effects ; Receptors, Complement/deficiency ; Receptors, Complement/genetics ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sustained activation of C3aR in a human podocyte line impairs the morphological maturation of the cells.
Autorzy:
Zheng JM; Department of Nephrology, Taizhou Hospital, Wenzhou Medical University, Linhai, Zhejiang 317000, P.R. China.
Wang SS; Department of Nephrology, Taizhou Hospital, Wenzhou Medical University, Linhai, Zhejiang 317000, P.R. China.
Tian X; Department of Nephrology, Taizhou Hospital, Wenzhou Medical University, Linhai, Zhejiang 317000, P.R. China.
Che DJ; Department of Nephrology, Taizhou Hospital, Wenzhou Medical University, Linhai, Zhejiang 317000, P.R. China.
Pokaż więcej
Źródło:
Molecular medicine reports [Mol Med Rep] 2020 Dec; Vol. 22 (6), pp. 5326-5338. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Podocytes/*metabolism
Receptors, Complement/*metabolism
Arginine/analogs & derivatives ; Arginine/pharmacology ; Benzhydryl Compounds/pharmacology ; Cell Line ; Complement Activation ; Complement C3a/metabolism ; Humans ; Receptors, Complement/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration.
Autorzy:
Little K; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
Llorián-Salvador M; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
Tang M; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
Du X; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
Marry S; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
Chen M; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
Xu H; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK. .
Pokaż więcej
Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2020 Nov 25; Vol. 17 (1), pp. 355. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji:
Journal Article
MeSH Terms:
Macrophages/*pathology
Macular Degeneration/*pathology
Myofibroblasts/*pathology
Neovascularization, Pathologic/*pathology
Retina/*pathology
Animals ; Cells, Cultured ; Complement C3a/toxicity ; Female ; Fibrosis ; Humans ; Macrophages/drug effects ; Macrophages/immunology ; Macular Degeneration/chemically induced ; Macular Degeneration/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Myofibroblasts/drug effects ; Myofibroblasts/immunology ; Neovascularization, Pathologic/chemically induced ; Neovascularization, Pathologic/immunology ; Retina/drug effects ; Retina/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Heparin and non-anticoagulant heparin attenuate histone-induced inflammatory responses in whole blood.
Autorzy:
Hogwood J; National Institute for Biological Standards and Control, South Mimms, Ridge, Herts, United Kingdom.; Sacker Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, United Kingdom.
Pitchford S; Sacker Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, United Kingdom.
Mulloy B; Sacker Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, United Kingdom.
Page C; Sacker Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, United Kingdom.
Gray E; National Institute for Biological Standards and Control, South Mimms, Ridge, Herts, United Kingdom.; Sacker Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, United Kingdom.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2020 May 29; Vol. 15 (5), pp. e0233644. Date of Electronic Publication: 2020 May 29 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Anticoagulants/*pharmacology
Heparin/*pharmacology
Histones/*immunology
Inflammation/*drug therapy
Anti-Inflammatory Agents/chemistry ; Anticoagulants/chemistry ; Complement C3a/analysis ; Complement C3a/immunology ; Heparin/analogs & derivatives ; Histones/blood ; Humans ; Inflammation/blood ; Inflammation/immunology ; Interleukin-6/blood ; Interleukin-6/immunology ; Interleukin-8/blood ; Interleukin-8/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Acylation stimulating protein, complement C3 and lipid metabolism in ketosis-prone diabetic subjects.
Autorzy:
Liu Y; Centre de Recherche de l'Institut Universitaire de Cardiologie & Pneumologie de Québec, Université Laval, Québec, Canada; Department of Pediatrics, Tongji Hospital, HuaZhong University of Science and Technology, Wuhan, Hubei, P. R. China.
Gupta P; Centre de Recherche de l'Institut Universitaire de Cardiologie & Pneumologie de Québec, Université Laval, Québec, Canada.
Lapointe M; Centre de Recherche de l'Institut Universitaire de Cardiologie & Pneumologie de Québec, Université Laval, Québec, Canada.
Yotsapon T; Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Sarat S; Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Cianflone K; Centre de Recherche de l'Institut Universitaire de Cardiologie & Pneumologie de Québec, Université Laval, Québec, Canada.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2014 Oct 02; Vol. 9 (10), pp. e109237. Date of Electronic Publication: 2014 Oct 02 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lipid Metabolism*
Complement C3a/*metabolism
Diabetes Mellitus, Type 1/*metabolism
Diabetic Ketoacidosis/*metabolism
Adipokines/blood ; Adiposity ; Adolescent ; Adult ; Complement C3a/analysis ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/drug therapy ; Diabetic Ketoacidosis/blood ; Diabetic Ketoacidosis/drug therapy ; Fatty Acids, Nonesterified/blood ; Fatty Acids, Nonesterified/metabolism ; Female ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Male ; Middle Aged ; Postprandial Period ; Triglycerides/blood ; Triglycerides/metabolism ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Complement C3 and C5 deficiency affects fracture healing.
Autorzy:
Ehrnthaller C; Department of Traumatology, Hand-, Plastic-, and Reconstructive Surgery, Center of Surgery, University of Ulm, Ulm, Germany.
Huber-Lang M
Nilsson P
Bindl R
Redeker S
Recknagel S
Rapp A
Mollnes T
Amling M
Gebhard F
Ignatius A
Pokaż więcej
Źródło:
PloS one [PLoS One] 2013 Nov 18; Vol. 8 (11), pp. e81341. Date of Electronic Publication: 2013 Nov 18 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bony Callus/*immunology
Complement C3a/*genetics
Complement C5a/*genetics
Fracture Healing/*genetics
Fractures, Bone/*genetics
Animals ; Biomechanical Phenomena ; Bony Callus/diagnostic imaging ; Bony Callus/pathology ; Complement Activation/genetics ; Complement C3a/deficiency ; Complement C3a/immunology ; Complement C5a/deficiency ; Complement C5a/immunology ; Elasticity ; Femur/diagnostic imaging ; Femur/injuries ; Fracture Healing/immunology ; Fractures, Bone/diagnostic imaging ; Fractures, Bone/immunology ; Gene Deletion ; Gene Expression/immunology ; Hardness ; Interleukin-6/biosynthesis ; Interleukin-6/metabolism ; Male ; Mice ; X-Ray Microtomography
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Lower level of complement component C3 and C3a in the plasma means poor outcome in the patients with hepatitis B virus related acute-on-chronic liver failure.
Autorzy:
Li Q; Department of Infectious Diseases, Huashan Hospital, Fudan University, No.12 Wurumqi Middle Road, Jing'an district, Room 508, Shanghai, 200040, People's Republic of China.
Lu Q; Department of Infectious Diseases, Huashan Hospital, Fudan University, No.12 Wurumqi Middle Road, Jing'an district, Room 508, Shanghai, 200040, People's Republic of China.
Zhu MQ; Department of Infectious Diseases, Huashan Hospital, Fudan University, No.12 Wurumqi Middle Road, Jing'an district, Room 508, Shanghai, 200040, People's Republic of China.
Huang C; Department of Infectious Diseases, Huashan Hospital, Fudan University, No.12 Wurumqi Middle Road, Jing'an district, Room 508, Shanghai, 200040, People's Republic of China.
Yu KK; Department of Infectious Diseases, Huashan Hospital, Fudan University, No.12 Wurumqi Middle Road, Jing'an district, Room 508, Shanghai, 200040, People's Republic of China.
Huang YX; Department of Infectious Diseases, Huashan Hospital, Fudan University, No.12 Wurumqi Middle Road, Jing'an district, Room 508, Shanghai, 200040, People's Republic of China.
Zhao X; Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, 200040, China.; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
Luo XG; Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.
Zheng JM; Department of Infectious Diseases, Huashan Hospital, Fudan University, No.12 Wurumqi Middle Road, Jing'an district, Room 508, Shanghai, 200040, People's Republic of China. .
Pokaż więcej
Źródło:
BMC gastroenterology [BMC Gastroenterol] 2020 Apr 15; Vol. 20 (1), pp. 106. Date of Electronic Publication: 2020 Apr 15.
Typ publikacji:
Journal Article
MeSH Terms:
Acute-On-Chronic Liver Failure/*diagnosis
Complement C3/*metabolism
Hepatitis B, Chronic/*complications
Acute-On-Chronic Liver Failure/blood ; Acute-On-Chronic Liver Failure/mortality ; Acute-On-Chronic Liver Failure/virology ; Adolescent ; Adult ; Biomarkers/blood ; Case-Control Studies ; Complement C3a/metabolism ; Enzyme-Linked Immunosorbent Assay ; Female ; Hepatitis B, Chronic/blood ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Prognosis ; ROC Curve ; Severity of Illness Index ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Integrating complement into the molecular pathogenesis of Hidradenitis Suppurativa.
Autorzy:
Grand D; Laboratory of Investigative Dermatology, The Rockefeller University, New York, NY, USA.; Albert Einstein College of Medicine, Bronx, NY, USA.
Navrazhina K; Laboratory of Investigative Dermatology, The Rockefeller University, New York, NY, USA.; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, Weill Cornell University, New York, NY, USA.
Frew JW; Laboratory of Investigative Dermatology, The Rockefeller University, New York, NY, USA.
Pokaż więcej
Źródło:
Experimental dermatology [Exp Dermatol] 2020 Jan; Vol. 29 (1), pp. 86-92. Date of Electronic Publication: 2019 Nov 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Complement C3a/*metabolism
Complement C5a/*metabolism
Hidradenitis Suppurativa/*immunology
Hidradenitis Suppurativa/*metabolism
Receptor, Anaphylatoxin C5a/*metabolism
Animals ; Female ; Hidradenitis Suppurativa/complications ; Humans ; Inflammasomes/metabolism ; Insulin Resistance ; Microbiota ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Neutrophils ; Obesity/complications ; Polycystic Ovary Syndrome/complications ; Skin/microbiology ; Th17 Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Celiac disease and complement activation in response to Streptococcus pneumoniae.
Autorzy:
Tjernberg AR; Department of Pediatrics, Kalmar County Hospital, SE-391 85, Kalmar, Sweden. .; School of Medical Sciences, Örebro University, SE-701 82, Örebro, Sweden. .
Woksepp H; Research section, Department of Development and Public Health, Kalmar County Hospital, SE-391 85, Kalmar, Sweden.
Sandholm K; Linnaeus Center for Biomaterials Chemistry, Linnaeus University, SE-391 82, Kalmar, Sweden.
Johansson M; Department of Clinical Microbiology, Kalmar County Hospital, SE-391 85, Kalmar, Sweden.; Department of Clinical and Experimental Medicine, Linköping University, SE-581 85, Linköping, Sweden.
Dahle C; Department of Clinical and Experimental Medicine, Linköping University, SE-581 85, Linköping, Sweden.; Department of Clinical Immunology and Transfusion Medicine, Linköping University Hospital, SE-581 85, Linköping, Sweden.
Ludvigsson JF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-171 77, Stockholm, Sweden.; Department of Pediatrics, Örebro University Hospital, SE-701 85, Örebro, Sweden.
Bonnedahl J; Department of Clinical and Experimental Medicine, Linköping University, SE-581 85, Linköping, Sweden.
Nilsson P; Linnaeus Center for Biomaterials Chemistry, Linnaeus University, SE-391 82, Kalmar, Sweden.; Department of Immunology, Oslo University Hospital, University of Oslo, 0424, Oslo, Norway.
Ekdahl KN; Linnaeus Center for Biomaterials Chemistry, Linnaeus University, SE-391 82, Kalmar, Sweden.; Department of Immunology, Genetics and Pathology, Uppsala University, SE-751 85, Uppsala, Sweden.
Pokaż więcej
Źródło:
European journal of pediatrics [Eur J Pediatr] 2020 Jan; Vol. 179 (1), pp. 133-140. Date of Electronic Publication: 2019 Nov 05.
Typ publikacji:
Journal Article
MeSH Terms:
Complement Activation*
Celiac Disease/*complications
Pneumococcal Infections/*etiology
Adolescent ; Biomarkers/blood ; Case-Control Studies ; Celiac Disease/immunology ; Celiac Disease/microbiology ; Child ; Complement C3a/metabolism ; Complement Membrane Attack Complex/metabolism ; Disease Susceptibility ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Male ; Pneumococcal Infections/immunology ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Predictive biomarkers for graft rejection in pig-to-non-human primate corneal xenotransplantation.
Autorzy:
Yoon CH; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Seoul Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea.
Choi SH; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Seoul Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea.
Lee HJ; Laboratory of Ocular Regenerative Medicine and Immunology, Seoul Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea.
Kang HJ; Department of Laboratory Medicine, Hallym University College of Medicine, Anyang-si, Republic of Korea.
Kim MK; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Seoul Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea.
Pokaż więcej
Źródło:
Xenotransplantation [Xenotransplantation] 2019 Jul; Vol. 26 (4), pp. e12515. Date of Electronic Publication: 2019 Apr 14.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Corneal Transplantation*
Antibodies, Heterophile/*blood
Biomarkers/*blood
Complement C3a/*analysis
Graft Rejection/*diagnosis
Immunoglobulin G/*blood
Immunoglobulin M/*blood
Lymphocyte Subsets/*immunology
Animals ; Complement Activation ; Graft Rejection/blood ; Graft Rejection/immunology ; Graft Rejection/prevention & control ; Heterografts ; Immunosuppressive Agents/therapeutic use ; Lymphocyte Count ; Macaca mulatta ; Predictive Value of Tests ; Retrospective Studies ; Swine ; Transplantation Immunology ; Transplantation, Heterologous
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pathological significance of urinary complement activation in diabetic nephropathy: A full view from the development of the disease.
Autorzy:
Zheng JM; Department of Nephrology Taizhou Hospital, Wenzhou Medical University, Lihai, Zhejiang Province, China.; National Clinical Research Center of Kidney Diseases, Jingling Hospital, Nanjing University School of Medicine, Nanjing, China.
Jiang ZH; Department of Nephrology Taizhou Hospital, Wenzhou Medical University, Lihai, Zhejiang Province, China.
Chen DJ; Department of Nephrology Taizhou Hospital, Wenzhou Medical University, Lihai, Zhejiang Province, China.
Wang SS; Department of Nephrology Taizhou Hospital, Wenzhou Medical University, Lihai, Zhejiang Province, China.
Zhao WJ; National Clinical Research Center of Kidney Diseases, Jingling Hospital, Nanjing University School of Medicine, Nanjing, China.
Li LJ; National Clinical Research Center of Kidney Diseases, Jingling Hospital, Nanjing University School of Medicine, Nanjing, China.
Pokaż więcej
Źródło:
Journal of diabetes investigation [J Diabetes Investig] 2019 May; Vol. 10 (3), pp. 738-744. Date of Electronic Publication: 2018 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Complement Activation*
Biomarkers/*urine
Complement C3a/*urine
Complement C5a/*urine
Complement Membrane Attack Complex/*urine
Diabetic Nephropathies/*pathology
Kidney Tubules/*pathology
Biomarkers/blood ; Case-Control Studies ; Diabetes Mellitus, Type 2/complications ; Diabetic Nephropathies/etiology ; Diabetic Nephropathies/urine ; Disease Progression ; Female ; Follow-Up Studies ; Humans ; Kidney Tubules/injuries ; Kidney Tubules/metabolism ; Male ; Middle Aged ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Complement profile in neonates of different gestational ages.
Autorzy:
Grumach AS; Department of Dermatology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil; Faculty of Medicine ABC, Outpatient Clinic of Recurrent Infections, São Paulo, Brazil.
Ceccon ME
Rutz R
Fertig A
Kirschfink M
Pokaż więcej
Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2014 Apr; Vol. 79 (4), pp. 276-81.
Typ publikacji:
Journal Article
MeSH Terms:
Complement C1 Inhibitor Protein/*metabolism
Complement C3a/*metabolism
Premature Birth/*immunology
Adult ; Complement Activation ; Complement C1 Inhibitor Protein/genetics ; Complement C3a/genetics ; Complement Factor H/genetics ; Complement Factor H/metabolism ; Complement Hemolytic Activity Assay ; Female ; Fibrinogen/genetics ; Fibrinogen/metabolism ; Gene Expression Regulation, Developmental ; Gestational Age ; Humans ; Infant, Newborn ; Mannose-Binding Lectin/genetics ; Mannose-Binding Lectin/metabolism ; Pregnancy ; Properdin/genetics ; Properdin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 285

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies