Temat: "Complement System Proteins" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Persistent complement dysregulation with signs of thromboinflammation in active Long Covid.
Autorzy:: Cervia-Hasler C; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Brüningk SC; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Hoch T; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Fan B; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Muzio G; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Thompson RC; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mount Sinai Clinical Intelligence Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Ceglarek L; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Meledin R; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Westermann P; Precision Proteomics Center, Swiss Institute of Allergy and Asthma Research, University of Zurich, 7265 Davos, Switzerland.
Emmenegger M; Institute of Neuropathology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Taeschler P; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Zurbuchen Y; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Pons M; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Menges D; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, 8001 Zurich, Switzerland.
Ballouz T; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, 8001 Zurich, Switzerland.
Cervia-Hasler S; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Adamo S; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Merad M; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Charney AW; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mount Sinai Clinical Intelligence Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Puhan M; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, 8001 Zurich, Switzerland.
Brodin P; Unit for Clinical Pediatrics, Department of Women's and Children's Health, Karolinska Institute, 17165 Solna, Sweden.; Department of Immunology and Inflammation, Imperial College London, London W12 0NN, UK.
Nilsson J; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Aguzzi A; Institute of Neuropathology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Raeber ME; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Messner CB; Precision Proteomics Center, Swiss Institute of Allergy and Asthma Research, University of Zurich, 7265 Davos, Switzerland.
Beckmann ND; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mount Sinai Clinical Intelligence Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Division of Data Driven and Digital Medicine (D3M), Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Borgwardt K; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Boyman O; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.; Faculty of Medicine and Faculty of Science, University of Zurich, 8006 Zurich, Switzerland.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2024 Jan 19; Vol. 383 (6680), pp. eadg7942. Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:: Journal Article
MeSH Terms:: Complement Activation*
Complement System Proteins*/analysis
Complement System Proteins*/metabolism
Post-Acute COVID-19 Syndrome*/blood
Post-Acute COVID-19 Syndrome*/complications
Post-Acute COVID-19 Syndrome*/immunology
Thromboinflammation*/blood
Thromboinflammation*/immunology
Proteome*
Humans ; Biomarkers/blood ; Proteomics ; Male ; Female ; Young Adult ; Adult ; Middle Aged ; Aged

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Skocz do pozycji: 2.

Tytuł:: Immune damage in Long Covid.
Autorzy:: Ruf W; Center for Thrombosis and Hemostasis, Johannes-Gutenberg- University Medical Center Mainz, Mainz, Germany.; Scripps Research, La Jolla, CA, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2024 Jan 19; Vol. 383 (6680), pp. 262-263. Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:: Journal Article
MeSH Terms:: Blood Coagulation*/immunology
Complement System Proteins*/analysis
Complement System Proteins*/immunology
Post-Acute COVID-19 Syndrome*/blood
Post-Acute COVID-19 Syndrome*/immunology
Humans

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Skocz do pozycji: 3.

Tytuł:: Variants in complement genes are uncommon in patients with anti-factor H autoantibody-associated atypical hemolytic uremic syndrome.
Autorzy:: Khandelwal P; Division of Nephrology, Department of Pediatrics, ICMR Center for Advanced Research in Nephrology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Joshi A; Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology, Delhi, India.
Mathur A; Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology, Delhi, India.
Puraswani M; Division of Nephrology, Department of Pediatrics, ICMR Center for Advanced Research in Nephrology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Gurjar BS; Division of Nephrology, Department of Pediatrics, ICMR Center for Advanced Research in Nephrology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Sinha A; Division of Nephrology, Department of Pediatrics, ICMR Center for Advanced Research in Nephrology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Hari P; Division of Nephrology, Department of Pediatrics, ICMR Center for Advanced Research in Nephrology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Faruq M; Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology, Delhi, India.
Bagga A; Division of Nephrology, Department of Pediatrics, ICMR Center for Advanced Research in Nephrology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India. .; Pokaż więcej
Źródło:: Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2023 Aug; Vol. 38 (8), pp. 2659-2668. Date of Electronic Publication: 2023 Jan 09.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms:: Atypical Hemolytic Uremic Syndrome*/genetics
Complement System Proteins*/genetics
Child ; Humans ; Autoantibodies ; Complement Factor H/genetics ; Homozygote ; Prospective Studies ; Sequence Deletion

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Skocz do pozycji: 4.

Tytuł:: Dynamics and Molecular Interactions of GPI-Anchored CD59.
Autorzy:: Voisin TB; Department of Life Sciences, Sir Ernst Chain Building, Imperial College London, London SW7 2AZ, UK.
Couves EC; Department of Life Sciences, Sir Ernst Chain Building, Imperial College London, London SW7 2AZ, UK.
Tate EW; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK.
Bubeck D; Department of Life Sciences, Sir Ernst Chain Building, Imperial College London, London SW7 2AZ, UK.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2023 Jun 30; Vol. 15 (7). Date of Electronic Publication: 2023 Jun 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Complement Membrane Attack Complex*/metabolism
Complement System Proteins*
Humans ; CD59 Antigens/chemistry ; CD59 Antigens/metabolism ; Bacteria/metabolism

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Skocz do pozycji: 5.

Tytuł:: Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation.
Autorzy:: Sandomenico A; Institute of Biostructures and Bioimaging (IBB), National Research Council (CNR), I-80131 Napoli, Italy.
Ruggiero A; Institute of Biostructures and Bioimaging (IBB), National Research Council (CNR), I-80131 Napoli, Italy.
Iaccarino E; Institute of Biostructures and Bioimaging (IBB), National Research Council (CNR), I-80131 Napoli, Italy.
Oliver A; Institute of Biostructures and Bioimaging (IBB), National Research Council (CNR), I-80131 Napoli, Italy.
Squeglia F; Institute of Biostructures and Bioimaging (IBB), National Research Council (CNR), I-80131 Napoli, Italy.
Moreira M; Institute of Biostructures and Bioimaging (IBB), National Research Council (CNR), I-80131 Napoli, Italy.
Esposito L; Institute of Biostructures and Bioimaging (IBB), National Research Council (CNR), I-80131 Napoli, Italy.
Ruvo M; Institute of Biostructures and Bioimaging (IBB), National Research Council (CNR), I-80131 Napoli, Italy.
Berisio R; Institute of Biostructures and Bioimaging (IBB), National Research Council (CNR), I-80131 Napoli, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 10; Vol. 24 (10). Date of Electronic Publication: 2023 May 10.
Typ publikacji:: Journal Article
MeSH Terms:: Complement System Proteins*/metabolism
HIV-1*/physiology
Humans ; Binding Sites, Antibody ; CD59 Antigens/metabolism ; Complement Membrane Attack Complex/metabolism ; Complement Inactivating Agents

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Skocz do pozycji: 6.

Tytuł:: The complement system in pediatric acute kidney injury.
Autorzy:: Stenson EK; Section of Pediatric Critical Care Medicine, Department of Pediatrics, University of Colorado School of Medicine, 13121 E 17th Avenue, MS8414, Aurora, CO, 80045, USA. .
Kendrick J; Division of Renal Disease and Hypertension, Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
Dixon B; Renal Section, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
Thurman JM; Division of Renal Disease and Hypertension, Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.; Pokaż więcej
Źródło:: Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2023 May; Vol. 38 (5), pp. 1411-1425. Date of Electronic Publication: 2022 Oct 06.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:: Complement System Proteins*
Kidney*/pathology
Kidney Diseases*/therapy
Atypical Hemolytic Uremic Syndrome/therapy ; Complement Activation ; Humans ; Child

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Skocz do pozycji: 7.

Tytuł:: Recombinant Acetylcholine Receptor Immunization Induces a Robust Model of Experimental Autoimmune Myasthenia Gravis in Mice.
Autorzy:: Theissen L; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Schroeter CB; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Huntemann N; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Räuber S; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Dobelmann V; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Cengiz D; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Herrmann A; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Koch-Hölsken K; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Gerdes N; Department of Cardiology, Pulmonolgy and Vascular Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Hu H; Department of Cardiology, Pulmonolgy and Vascular Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Mourikis P; Department of Cardiology, Pulmonolgy and Vascular Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Polzin A; Department of Cardiology, Pulmonolgy and Vascular Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Kelm M; Department of Cardiology, Pulmonolgy and Vascular Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Hartung HP; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.; Brain and Mind Center, University of Sidney, Sidney NSW 2050, Australia.; Department of Neurology, Palacky University Olomouc, 77146 Olomouc, Czech Republic.
Meuth SG; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Nelke C; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Ruck T; Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Mar 14; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:: Journal Article
MeSH Terms:: Receptors, Cholinergic*
Myasthenia Gravis, Autoimmune, Experimental*/drug therapy
Myasthenia Gravis, Autoimmune, Experimental*/metabolism
Mice ; Animals ; Neuromuscular Junction/pathology ; Complement System Proteins ; Autoantibodies ; Immunization

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Skocz do pozycji: 8.

Tytuł:: A tick saliva serpin, IxsS17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent.
Autorzy:: Nguyen TT; Department of Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America.
Kim TH; Department of Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America.
Bencosme-Cuevas E; Department of Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America.
Berry J; Department of Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America.
Gaithuma ASK; Department of Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America.
Ansari MA; Department of Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America.
Kim TK; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, United States of America.
Tirloni L; Tick-Pathogen Transmission Unit, Laboratory of Bacteriology, NIAID, Hamilton, Montana, United States of America.
Radulovic Z; Department of Biology, Stephen F. Austin State University, Nacogdoches, Texas, United States of America.
Moresco JJ; Center for Genetics of Host Defense, UT Southwestern Medical Center, Dallas, Texas, United States of America.
Yates JR 3rd; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California, United States of America.
Mulenga A; Department of Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2024 Feb 23; Vol. 20 (2), pp. e1012032. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Serpins*/metabolism
Lyme Disease*
Ixodes*
Borrelia burgdorferi*
Mice ; Animals ; Humans ; Saliva/metabolism ; Peptide Hydrolases ; Mice, Inbred C3H ; Complement System Proteins ; Endopeptidases ; Immune System/metabolism

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Skocz do pozycji: 9.

Tytuł:: The Role of Complement Dysregulation in Glaucoma.
Autorzy:: Hoppe C; Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA.; Animal Physiology/Neurobiology, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany.
Gregory-Ksander M; Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 15; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Neurodegenerative Diseases*/pathology
Glaucoma*/metabolism
Animals ; Humans ; Retinal Ganglion Cells/metabolism ; Complement System Proteins ; Inflammation/pathology ; Disease Models, Animal

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Skocz do pozycji: 10.

Tytuł:: Complement-mediated dialysis reaction during regular hemodialysis treatment: a case report.
Autorzy:: Pethő Á; Department of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Korányi S. U. 2/a, 1083, Budapest, Hungary. .
Schnabel K; Department of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Korányi S. U. 2/a, 1083, Budapest, Hungary.
Dézsi L; SeroScience Ltd., Budapest, Hungary.; Nanomedicine Research and Education Center, Institute of Translational Medicine, Semmelweis University, Budapest, Hungary.; Pokaż więcej
Źródło:: Journal of medical case reports [J Med Case Rep] 2024 Feb 08; Vol. 18 (1), pp. 46. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Hypersensitivity*/etiology
Renal Dialysis*/adverse effects
Humans ; Male ; Middle Aged ; Complement System Proteins ; Polymers/adverse effects ; Sulfones

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Skocz do pozycji: 11.

Tytuł:: Anti-aquaporin-4 immune complex stimulates complement-dependent Th17 cytokine release in neuromyelitis optica spectrum disorders.
Autorzy:: Nishiyama S; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA. .; Harvard Medical School, Boston, MA, USA. .; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan. .; Department of Neurology, Massachusetts General Hospital, 65 Landsdowne, Lab 500, Cambridge, MA, 02139, USA. .
Seok JM; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Wright AE; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Lotan I; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Mikami T; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Drosu NC; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Bobrowski-Khoury N; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Anderson MR; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Bilodeau PA; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Schindler P; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Paul F; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Aoki M; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
Yeaman MR; Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Division of Molecular Medicine, David Geffen School of Medicine at UCLA, Institute for Infection and Immunity, Harbor-UCLA Medical Center, Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
Levy M; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Pokaż więcej
Corporate Authors:: Guthy-Jackson Charitable Foundation CIRCLES Study Group
Źródło:: Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3146. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:: Journal Article
MeSH Terms:: Neuromyelitis Optica*
Humans ; Cytokines/metabolism ; Antigen-Antibody Complex/metabolism ; Leukocytes, Mononuclear/metabolism ; Interleukin-17/metabolism ; Interleukin-6/metabolism ; Rituximab/pharmacology ; Rituximab/therapeutic use ; Rituximab/metabolism ; Autoantibodies ; Aquaporin 4 ; Complement System Proteins/metabolism ; Immunoglobulin G/metabolism

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Skocz do pozycji: 12.

Tytuł:: Gene targeting as a therapeutic avenue in diseases mediated by the complement alternative pathway.
Autorzy:: Dreismann AK; Gyroscope Therapeutics Limited, London, UK.
Hallam TM; Gyroscope Therapeutics Limited, London, UK.
Tam LC; Gyroscope Therapeutics Limited, London, UK.
Nguyen CV; Gyroscope Therapeutics Limited, London, UK.
Hughes JP; Gyroscope Therapeutics Limited, London, UK.
Ellis S; Gyroscope Therapeutics Limited, London, UK.
Harris CL; Gyroscope Therapeutics Limited, London, UK.; Pokaż więcej
Źródło:: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 402-419. Date of Electronic Publication: 2022 Nov 12.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Complement System Proteins*/genetics
Complement System Proteins*/metabolism
Hemoglobinuria, Paroxysmal*/drug therapy
Hemoglobinuria, Paroxysmal*/genetics
Humans ; Gene Targeting ; Complement Pathway, Alternative

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Skocz do pozycji: 13.

Tytuł:: Complement Cascade Proteins Correlate with Fibrosis and Inflammation in Early-Stage Type 1 Diabetic Kidney Disease in the Ins2Akita Mouse Model.
Autorzy:: Tserga A; Biomedical Research Foundation, Academy of Athens, Department of Biotechnology, Soranou Efessiou 4, 11527 Athens, Greece.
Saulnier-Blache JS; Institut National de la Santé et de la Recherche Médicale (INSERM), UMR1297, Institute of Cardiovascular and Metabolic Disease, 31432 Toulouse, France.; Department of Biology, Université Toulouse III Paul-Sabatier, 31062 Toulouse, France.
Palamaris K; 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, 34400 Athens, Greece.
Pouloudi D; 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, 34400 Athens, Greece.
Gakiopoulou H; 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, 34400 Athens, Greece.
Zoidakis J; Biomedical Research Foundation, Academy of Athens, Department of Biotechnology, Soranou Efessiou 4, 11527 Athens, Greece.; Department of Biology, National and Kapodistrian University of Athens, 15701 Zografou, Greece.
Schanstra JP; Institut National de la Santé et de la Recherche Médicale (INSERM), UMR1297, Institute of Cardiovascular and Metabolic Disease, 31432 Toulouse, France.; Department of Biology, Université Toulouse III Paul-Sabatier, 31062 Toulouse, France.
Vlahou A; Biomedical Research Foundation, Academy of Athens, Department of Biotechnology, Soranou Efessiou 4, 11527 Athens, Greece.
Makridakis M; Biomedical Research Foundation, Academy of Athens, Department of Biotechnology, Soranou Efessiou 4, 11527 Athens, Greece.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 23; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetic Nephropathies*/genetics
Diabetic Nephropathies*/metabolism
Diabetes Mellitus, Type 1*/complications
Diabetes Mellitus, Type 1*/genetics
Diabetes Mellitus, Type 1*/metabolism
Diabetes Mellitus, Experimental*/metabolism
Humans ; Mice ; Animals ; Inflammation/metabolism ; Disease Models, Animal ; Complement System Proteins/genetics ; Complement System Proteins/metabolism ; Fibrosis ; Kidney/metabolism

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Skocz do pozycji: 14.

Tytuł:: The Sertoli Cell Complement Signature: A Suspected Mechanism in Xenograft Survival.
Autorzy:: Washburn RL; Department of Cell Biology and Biochemistry, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79424, USA.; Department of Immunology and Molecular Microbiology, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79404, USA.
Martinez-Marin D; Department of Cell Biology and Biochemistry, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79424, USA.; Department of Immunology and Molecular Microbiology, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79404, USA.
Korać K; Department of Cell Biology and Biochemistry, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79424, USA.
Sniegowski T; Department of Cell Biology and Biochemistry, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79424, USA.
Rodriguez AR; Department of Cell Biology and Biochemistry, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79424, USA.
Chilton BS; Department of Cell Biology and Biochemistry, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79424, USA.
Hibler T; Department of Cell Biology and Biochemistry, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79424, USA.; Department of Immunology and Molecular Microbiology, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79404, USA.
Pruitt K; Department of Immunology and Molecular Microbiology, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79404, USA.
Bhutia YD; Department of Cell Biology and Biochemistry, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79424, USA.
Dufour JM; Department of Cell Biology and Biochemistry, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79424, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 18; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 18.
Typ publikacji:: Journal Article
MeSH Terms:: Complement System Proteins*/metabolism
Graft Rejection*/metabolism
Sertoli Cells*/metabolism
Humans ; Male ; Complement Inactivating Agents ; Heterografts ; Transplantation, Heterologous ; Swine ; Animals

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Skocz do pozycji: 15.

Tytuł:: The Complexity of the Post-Burn Immune Response: An Overview of the Associated Local and Systemic Complications.
Autorzy:: Korkmaz HI; Department of Plastic Reconstructive and Hand Surgery, Amsterdam Movement Sciences (AMS) Institute, Amsterdam UMC, Location VUmc, 1081 HZ Amsterdam, The Netherlands.; Department of Molecular Cell Biology and Immunology, Amsterdam Infection and Immunity (AII) Institute, Amsterdam UMC, Location VUmc, 1081 HZ Amsterdam, The Netherlands.; Burn Center and Department of Plastic and Reconstructive Surgery, Red Cross Hospital, 1942 LE Beverwijk, The Netherlands.; Association of Dutch Burn Centres (ADBC), 1941 AJ Beverwijk, The Netherlands.
Flokstra G; Department of Molecular Cell Biology and Immunology, Amsterdam Infection and Immunity (AII) Institute, Amsterdam UMC, Location VUmc, 1081 HZ Amsterdam, The Netherlands.
Waasdorp M; Department of Molecular Cell Biology and Immunology, Amsterdam Infection and Immunity (AII) Institute, Amsterdam UMC, Location VUmc, 1081 HZ Amsterdam, The Netherlands.; Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.
Pijpe A; Department of Plastic Reconstructive and Hand Surgery, Amsterdam Movement Sciences (AMS) Institute, Amsterdam UMC, Location VUmc, 1081 HZ Amsterdam, The Netherlands.; Burn Center and Department of Plastic and Reconstructive Surgery, Red Cross Hospital, 1942 LE Beverwijk, The Netherlands.; Association of Dutch Burn Centres (ADBC), 1941 AJ Beverwijk, The Netherlands.
Papendorp SG; Burn Center and Department of Plastic and Reconstructive Surgery, Red Cross Hospital, 1942 LE Beverwijk, The Netherlands.; Intensive Care Unit, Red Cross Hospital, 1942 LE Beverwijk, The Netherlands.
de Jong E; Burn Center and Department of Plastic and Reconstructive Surgery, Red Cross Hospital, 1942 LE Beverwijk, The Netherlands.; Intensive Care Unit, Red Cross Hospital, 1942 LE Beverwijk, The Netherlands.
Rustemeyer T; Department of Dermatology, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.
Gibbs S; Department of Molecular Cell Biology and Immunology, Amsterdam Infection and Immunity (AII) Institute, Amsterdam UMC, Location VUmc, 1081 HZ Amsterdam, The Netherlands.; Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.
van Zuijlen PPM; Department of Plastic Reconstructive and Hand Surgery, Amsterdam Movement Sciences (AMS) Institute, Amsterdam UMC, Location VUmc, 1081 HZ Amsterdam, The Netherlands.; Burn Center and Department of Plastic and Reconstructive Surgery, Red Cross Hospital, 1942 LE Beverwijk, The Netherlands.; Association of Dutch Burn Centres (ADBC), 1941 AJ Beverwijk, The Netherlands.; Paediatric Surgical Centre, Emma Children's Hospital, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Jan 17; Vol. 12 (3). Date of Electronic Publication: 2023 Jan 17.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Lymphocytes*
Complement System Proteins*
Acute-Phase Proteins ; Inflammation Mediators

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Skocz do pozycji: 16.

Tytuł:: Local complement synthesis-A process with near and far consequences for ischemia reperfusion injury and transplantation.
Autorzy:: Nauser CL; Duke University, Durham, North Carolina, USA.
Sacks SH; King's College London, Guy's Hospital, London, UK.; Pokaż więcej
Źródło:: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 320-326. Date of Electronic Publication: 2022 Oct 06.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Complement System Proteins*/metabolism
Reperfusion Injury*/metabolism
Humans ; Complement Activation ; Graft Rejection

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Skocz do pozycji: 17.

Tytuł:: Therapeutic regulation of complement activation in extracorporeal circuits and intravascular treatments with special reference to the alternative pathway amplification loop.
Autorzy:: Ekdahl KN; Department of Immunology, Genetics and Pathology (IGP), Rudbeck Laboratory C5:3, Uppsala University, Uppsala, Sweden.; Linnaeus Center of Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden.
Fromell K; Department of Immunology, Genetics and Pathology (IGP), Rudbeck Laboratory C5:3, Uppsala University, Uppsala, Sweden.
Mannes M; Institute for Clinical and Experimental Trauma-Immunology, University Hospital of Ulm, Ulm, Germany.
Grinnemo KH; Department of Surgical Sciences, Division of Cardiothoracic Surgery, Uppsala University, Uppsala University Hospital, Uppsala, Sweden.
Huber-Lang M; Institute for Clinical and Experimental Trauma-Immunology, University Hospital of Ulm, Ulm, Germany.
Teramura Y; Department of Immunology, Genetics and Pathology (IGP), Rudbeck Laboratory C5:3, Uppsala University, Uppsala, Sweden.; Cellular and Molecular Biotechnology Research Institute (CMB), National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.; Master's/Doctoral Program in Life Science Innovation (T-LSI), University of Tsukuba, Tsukuba, Japan.
Nilsson B; Department of Immunology, Genetics and Pathology (IGP), Rudbeck Laboratory C5:3, Uppsala University, Uppsala, Sweden.; Pokaż więcej
Źródło:: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 91-103. Date of Electronic Publication: 2022 Oct 18.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Complement Activation*
Complement System Proteins*
Humans ; Complement Pathway, Alternative

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Skocz do pozycji: 18.

Tytuł:: Age-related macular degeneration: A disease of extracellular complement amplification.
Autorzy:: de Jong S; Department for Ophthalmology, University Eye Clinic, Eberhard Karls University of Tübingen, Tübingen, Germany.; Department for Ophthalmology, Institute for Ophthalmic Research, Eberhard Karls University of Tübingen, Tübingen, Germany.
Tang J; Department for Ophthalmology, University Eye Clinic, Eberhard Karls University of Tübingen, Tübingen, Germany.; Department for Ophthalmology, Institute for Ophthalmic Research, Eberhard Karls University of Tübingen, Tübingen, Germany.
Clark SJ; Department for Ophthalmology, University Eye Clinic, Eberhard Karls University of Tübingen, Tübingen, Germany.; Department for Ophthalmology, Institute for Ophthalmic Research, Eberhard Karls University of Tübingen, Tübingen, Germany.; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Pokaż więcej
Źródło:: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 279-297. Date of Electronic Publication: 2022 Oct 12.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Complement System Proteins*
Macular Degeneration*/genetics
Macular Degeneration*/metabolism
Macular Degeneration*/therapy
Humans ; Complement Activation ; Aging ; Immune System/metabolism

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Skocz do pozycji: 19.

Tytuł:: Alternative pathway activation in pregnancy, a measured amount "complements" a successful pregnancy, too much results in adverse events.
Autorzy:: Smith-Jackson K; Complement Therapeutics Research Group, Translational and Clinical Research Institute, Faculty of Medical Science, Newcastle University, Newcastle-upon-Tyne, UK.; The National Renal Complement Therapeutics Centre (NRCTC), Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK.
Harrison RA; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.; Pokaż więcej
Źródło:: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 298-319. Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Complement System Proteins*
Pregnancy Complications*
Pregnancy ; Female ; Humans ; Complement Activation ; Adaptive Immunity

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Skocz do pozycji: 20.

Tytuł:: Intracellular complement: Evidence, definitions, controversies, and solutions.
Autorzy:: King BC; Department of Translational Medicine, Lund University, Malmö, Sweden.
Blom AM; Department of Translational Medicine, Lund University, Malmö, Sweden.; Pokaż więcej
Źródło:: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 104-119. Date of Electronic Publication: 2022 Sep 13.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Complement System Proteins*/metabolism
Humans

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