Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Complement factor H"" wg kryterium: Temat


Tytuł:
The human factor H protein family - an update.
Autorzy:
Sándor N; Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.; HUN-REN-ELTE Complement Research Group, Hungarian Research Network, Budapest, Hungary.
Schneider AE; Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.
Matola AT; Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.
Barbai VH; Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.
Bencze D; Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.
Hammad HH; Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.
Papp A; Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.
Kövesdi D; Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.; HUN-REN-ELTE Complement Research Group, Hungarian Research Network, Budapest, Hungary.
Uzonyi B; Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.; HUN-REN-ELTE Complement Research Group, Hungarian Research Network, Budapest, Hungary.
Józsi M; Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.; HUN-REN-ELTE Complement Research Group, Hungarian Research Network, Budapest, Hungary.
Pokaż więcej
Źródło:
Frontiers in immunology [Front Immunol] 2024 Feb 12; Vol. 15, pp. 1135490. Date of Electronic Publication: 2024 Feb 12 (Print Publication: 2024).
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Complement Factor H*/metabolism
Complement System Proteins*
Humans ; Complement Activation
Czasopismo naukowe
Tytuł:
Levels of complement factor H-related 4 protein do not influence susceptibility to age-related macular degeneration or its course of progression.
Autorzy:
Zouache MA; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA. .
Richards BT; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Pappas CM; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Anstadt RA; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Liu J; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Corsetti T; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Matthews S; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Seager NA; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Schmitz-Valckenberg S; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Fleckenstein M; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Hubbard WC; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Thomas J; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Hageman JL; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Williams BL; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.
Hageman GS; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA. .
Pokaż więcej
Źródło:
Nature communications [Nat Commun] 2024 Jan 10; Vol. 15 (1), pp. 443. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Complement Factor H*/genetics
Macular Degeneration*/genetics
Humans ; Bruch Membrane ; Choroid ; Cognition
Czasopismo naukowe
Tytuł:
Efficacy of GalNAc C3 siRNAs in factor H-deficient mice with C3 glomerulopathy.
Autorzy:
Zanchi C; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.
Locatelli M; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.
Cerullo D; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.
Aumiller V; Silence Therapeutics GmbH, Berlin, Germany.
Corna D; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.
Rottoli D; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.
Schubert S; Silence Therapeutics GmbH, Berlin, Germany.
Noris M; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.
Tomasoni S; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.
Remuzzi G; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.
Zoja C; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.
Benigni A; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy. Electronic address: .
Pokaż więcej
Źródło:
Molecular immunology [Mol Immunol] 2024 Apr; Vol. 168, pp. 10-16. Date of Electronic Publication: 2024 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Glomerulonephritis, Membranoproliferative*/genetics
Glomerulonephritis, Membranoproliferative*/drug therapy
Glomerulonephritis, Membranoproliferative*/metabolism
Kidney Diseases*
Hereditary Complement Deficiency Diseases*
Complement Factor H/*deficiency
Humans ; Animals ; Mice ; Complement C3/genetics ; Complement C3/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/therapeutic use ; Complement Factor H/genetics ; Complement Factor H/therapeutic use ; Complement Pathway, Alternative
SCR Disease Name:
Complement Factor H Deficiency
Czasopismo naukowe
Tytuł:
Identification of complement factor H variants that predispose to pre-eclampsia: A genetic and functional study.
Autorzy:
Lokki AI; Immunobiology Research Program, Bacteriology and Immunology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Heart and Lung Centre, Helsinki University Hospital, Helsinki, Finland.
Ren Z; Division of Clinical Immunology and Allergy, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Triebwasser M; Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA.
Daly E; Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Perola M; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.
Auro K; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.
Burwick R; Maternal Fetal Medicine, San Gabriel Valley Perinatal Medical Group, Pomona Valley Hospital Medical Center, Pomona, California, USA.; Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Salmon JE; Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York, USA.
Daly M; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.
Laivuori H; Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; Department of Obstetrics and Gynaecology, Tampere University Hospital, Tampere University, Tampere, Finland.; Centre for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Atkinson JP; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Java A; Division of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Meri S; Immunobiology Research Program, Bacteriology and Immunology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; HUSLAB Diagnostic Centre, Helsinki University Hospital, Helsinki, Finland.
Pokaż więcej
Corporate Authors:
FINNPEC; Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Źródło:
BJOG : an international journal of obstetrics and gynaecology [BJOG] 2023 Nov; Vol. 130 (12), pp. 1473-1482. Date of Electronic Publication: 2023 May 08.
Typ publikacji:
Journal Article
MeSH Terms:
Complement Factor H*/genetics
Complement Factor H*/metabolism
Pre-Eclampsia*/genetics
Humans ; Pregnancy ; Female ; Case-Control Studies ; Placenta/metabolism ; Genotype
Czasopismo naukowe
Tytuł:
Complement and coagulation crosstalk - Factor H in the spotlight.
Autorzy:
Heurich M; School of Pharmacy and Pharmaceutical Sciences, College of Biomedical and Life Sciences, Cardiff University, United Kingdom. Electronic address: .
McCluskey G; Université Paris-Saclay, INSERM, Hémostase, Inflammation, Thrombose HITH U1176, 94276 Le Kremlin-Bicêtre, France.
Pokaż więcej
Źródło:
Immunobiology [Immunobiology] 2023 Nov; Vol. 228 (6), pp. 152707. Date of Electronic Publication: 2023 Jul 12.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Complement Factor H*
Thrombosis*
Humans ; Blood Coagulation/physiology ; Blood Coagulation Factors/metabolism ; Complement System Proteins/metabolism ; Complement Activation
Czasopismo naukowe
Tytuł:
AAV Gene Augmentation of Truncated Complement Factor H Differentially Rescues Ocular Complement Dysregulation in a Mouse Model.
Autorzy:
Grigsby D; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.
Klingeborn M; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.; McLaughlin Research Institute, Great Falls, Montana, United States.
Kelly U; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.
Chew LA; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.; Department of Cell Biology, Duke University School of Medicine, Durham, North Carolina, United States.
Asokan A; Departments of Surgery, Molecular Genetics and Microbiology, and Biomedical Engineering, Duke University School of Medicine, Durham, North Carolina, United States.
Devlin G; Departments of Surgery, Molecular Genetics and Microbiology, and Biomedical Engineering, Duke University School of Medicine, Durham, North Carolina, United States.
Smith S; Applied Genetic Technologies Corporation, Alachua, Florida, United States.
Keyes L; Pfizer, Morrisville, North Carolina, United States.
Timmers A; Editas Medicine, Cambridge, Massachusetts, United States.
Scaria A; Applied Genetic Technologies Corporation, Alachua, Florida, United States.
Bowes Rickman C; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States.; Department of Cell Biology, Duke University School of Medicine, Durham, North Carolina, United States.
Pokaż więcej
Źródło:
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2023 Jul 03; Vol. 64 (10), pp. 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Complement Factor H*/genetics
Complement Factor H*/metabolism
Macular Degeneration*/genetics
Animals ; Humans ; Mice ; Liver/metabolism ; Polymorphism, Single Nucleotide ; Retina/metabolism ; Mice, Knockout
Czasopismo naukowe
Tytuł:
Alzheimer's disease-associated complement gene variants influence plasma complement protein levels.
Autorzy:
Veteleanu A; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.
Stevenson-Hoare J; Neurosciences and Mental Health Institute, Cardiff University, Cardiff, CF244HQ, UK.
Keat S; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.
Daskoulidou N; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.
Zetterberg H; UK Dementia Research Institute at University College London, London, WC1E6BT, UK.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Psychology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N3BG, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.
Heslegrave A; UK Dementia Research Institute at University College London, London, WC1E6BT, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N3BG, UK.
Escott-Price V; Neurosciences and Mental Health Institute, Cardiff University, Cardiff, CF244HQ, UK.
Williams J; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.
Sims R; Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, CF244HQ, UK.
Zelek WM; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.
Carpanini SM; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.
Morgan BP; UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK. .
Pokaż więcej
Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2023 Jul 21; Vol. 20 (1), pp. 169. Date of Electronic Publication: 2023 Jul 21.
Typ publikacji:
Journal Article
MeSH Terms:
Complement Factor H*/genetics
Alzheimer Disease*/genetics
Humans ; Clusterin/genetics ; Amyloid beta-Peptides ; Complement C1q ; Genome-Wide Association Study ; Complement System Proteins/genetics
Czasopismo naukowe
Tytuł:
Factor H autoantibodies contribute to complement dysregulation in multisystem inflammatory syndrome in children (MIS-C).
Autorzy:
Zerra PE; Center for Transfusion Medicine and Cellular Therapies, Department of Laboratory Medicine and Pathology, Emory University, Atlanta, Georgia, USA.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA.
Stowell J; School of Public Health, Boston University, Boston, Massachusetts, USA.
Verkerke H; Center for Transfusion Medicine and Cellular Therapies, Department of Laboratory Medicine and Pathology, Emory University, Atlanta, Georgia, USA.
McCoy J; Center for Transfusion Medicine and Cellular Therapies, Department of Laboratory Medicine and Pathology, Emory University, Atlanta, Georgia, USA.
Jones J; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA.
Graciaa S; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA.
Lu A; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
Hussaini L; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
Anderson EJ; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Rostad CA; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Stowell SR; Joint Program in Transfusion Medicine, Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.
Chonat S; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA.
Pokaż więcej
Źródło:
American journal of hematology [Am J Hematol] 2023 May; Vol. 98 (5), pp. E98-E101. Date of Electronic Publication: 2023 Feb 13.
Typ publikacji:
Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Complement Factor H*
Systemic Inflammatory Response Syndrome*
Child ; Humans
SCR Disease Name:
pediatric multisystem inflammatory disease, COVID-19 related
Raport
Tytuł:
Preferential production and secretion of the complement regulator factor H-like protein 1 (FHL-1) by human myeloid cells.
Autorzy:
van Essen MF; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: m.f.van_.
Peereboom ETM; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Schlagwein N; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands.
van Gijlswijk-Janssen DJ; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Nelemans T; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Joeloemsingh JV; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands.
van den Berg CW; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Prins J; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Clark SJ; Institute for Ophthalmic Research, Eberhard Karls University of Tübingen, Tübingen, Baden-Württemberg 72076, Germany; Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom.
Schmidt CQ; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, Ulm, Germany.
Trouw LA; Department of Immunology, Leiden University Medical Center, Leiden, the Netherlands.
van Kooten C; Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: c.van_.
Pokaż więcej
Źródło:
Immunobiology [Immunobiology] 2023 May; Vol. 228 (3), pp. 152364. Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Complement Factor H*/genetics
Complement Activation*
Humans ; Myeloid Cells/metabolism ; RNA, Messenger ; Muscle Proteins ; Intracellular Signaling Peptides and Proteins ; LIM Domain Proteins
Czasopismo naukowe
Tytuł:
Thrombospondin-1, BIM and CFH polymorphisms and response to anti-VEGF treatment in neovascular age- related macular degeneration patients.
Autorzy:
Sorenson, Christine M. (AUTHOR)
Gurel, Zafer (AUTHOR)
Song, Yong-Seok (AUTHOR)
Peterson, Kyle D. (AUTHOR)
Blodi, Barbara A. (AUTHOR)
Sheibani, Nader (AUTHOR)
Pokaż więcej
Źródło:
PLoS ONE. 2/26/2024, Vol. 19 Issue 2, p1-16. 16p.
Czasopismo naukowe
Tytuł:
Complement-regulatory biomaterial coatings: Activity and selectivity profile of the factor H-binding peptide 5C6.
Autorzy:
Bechtler C; Molecular Pharmacy Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland.
Koutsogiannaki S; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 422 Curie Blvd., Philadelphia, PA 19104, USA.
Umnyakova E; Molecular Pharmacy Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland.
Hamid A; Molecular Pharmacy Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland.
Gautam A; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 422 Curie Blvd., Philadelphia, PA 19104, USA.
Sarigiannis Y; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 422 Curie Blvd., Philadelphia, PA 19104, USA.
Pouw RB; Molecular Pharmacy Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland.
Lamers C; Molecular Pharmacy Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland.
Rabbani S; Molecular Pharmacy Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland.
Schmidt CQ; Institute of Experimental and Clinical Pharmacology, Toxicology and Pharmacology of Natural Products, University of Ulm Medical Center, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Lambris JD; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 422 Curie Blvd., Philadelphia, PA 19104, USA. Electronic address: .
Ricklin D; Molecular Pharmacy Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland. Electronic address: .
Pokaż więcej
Źródło:
Acta biomaterialia [Acta Biomater] 2023 Jan 01; Vol. 155, pp. 123-138. Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Complement Factor H*/chemistry
Complement Factor H*/metabolism
Complement C3b*/chemistry
Complement C3b*/metabolism
Animals ; Mice ; Biocompatible Materials/pharmacology ; Protein Binding ; Peptides/pharmacology ; Peptides/metabolism
Czasopismo naukowe
Tytuł:
Protective role of complement factor H against the development of preeclampsia.
Autorzy:
Yasmin H; Immunology and Cell Biology Laboratory, Department of Zoology, Cooch Behar Panchanan Barma University, Cooch Behar, West Bengal, India.
Agostinis C; Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.
Toffoli M; Department of Medical, Surgical and Health Science, University of Trieste, Trieste, Italy.
Roy T; Immunology and Cell Biology Laboratory, Department of Zoology, Cooch Behar Panchanan Barma University, Cooch Behar, West Bengal, India.
Pegoraro S; Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.
Balduit A; Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.
Zito G; Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.
Di Simone N; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Humanitas Research Hospital, Milan, Italy.
Ricci G; Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.; Department of Medical, Surgical and Health Science, University of Trieste, Trieste, Italy.
Madan T; Department of Innate Immunity, ICMR-National Institute for Research in Reproductive and Child Health (NIRRCH), Mumbai, India.
Kishore U; Department of Veterinary Medicine, U.A.E. University, Al Ain, United Arab Emirates.; Zayed Centre for Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Bulla R; Department of Life Sciences, University of Trieste, Trieste, Italy.
Pokaż więcej
Źródło:
Frontiers in immunology [Front Immunol] 2024 Feb 23; Vol. 15, pp. 1351898. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Placenta*/metabolism
Pre-Eclampsia*/metabolism
Female ; Humans ; Pregnancy ; Complement Factor H/metabolism ; Endothelial Cells/metabolism ; Trophoblasts/metabolism
Czasopismo naukowe
Tytuł:
Factor H's Control of Complement Activation Emerges as a Significant and Promising Therapeutic Target for Alzheimer's Disease Treatment.
Autorzy:
Hasantari I; INSERM (Institut National de la Santé et de la Recherche Médicale), Biologie des Maladies Cardiovasculaires, U1034, University Bordeaux, F-33600 Pessac, France.
Nicolas N; INSERM (Institut National de la Santé et de la Recherche Médicale), Biologie des Maladies Cardiovasculaires, U1034, University Bordeaux, F-33600 Pessac, France.
Alzieu P; INSERM (Institut National de la Santé et de la Recherche Médicale), Biologie des Maladies Cardiovasculaires, U1034, University Bordeaux, F-33600 Pessac, France.
Leval L; INSERM (Institut National de la Santé et de la Recherche Médicale), Biologie des Maladies Cardiovasculaires, U1034, University Bordeaux, F-33600 Pessac, France.
Shalabi A; Medizinische Hochschule Hannover, Abt. Infektiologie, 30625 Hannover, Germany.
Grolleau S; INSERM (Institut National de la Santé et de la Recherche Médicale), Biologie des Maladies Cardiovasculaires, U1034, University Bordeaux, F-33600 Pessac, France.
Dinet V; INSERM (Institut National de la Santé et de la Recherche Médicale), Biologie des Maladies Cardiovasculaires, U1034, University Bordeaux, F-33600 Pessac, France.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 14; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/metabolism
Mice ; Animals ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/metabolism ; Complement Factor H ; Mice, Transgenic ; Complement Activation ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Mechanisms by which Factor H protects Trypanosoma cruzi from the alternative pathway of complement.
Autorzy:
Menon SS; Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States.
Ramirez-Toloza G; Laboratory of Parasitology, Department of Animal Preventive Medicine, Faculty of Veterinary Medicine and Livestock Sciences, University of Chile, Santiago, Chile.
Wycoff KL; Planet Biotechnology, Inc., Hayward, CA, United States.
Ehinger S; Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States.
Shaughnessy J; Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA, United States.
Ram S; Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA, United States.
Ferreira VP; Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States.
Pokaż więcej
Źródło:
Frontiers in immunology [Front Immunol] 2024 Feb 01; Vol. 15, pp. 1152000. Date of Electronic Publication: 2024 Feb 01 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Trypanosoma cruzi*
Chagas Disease*/prevention & control
Humans ; Complement Factor H
Czasopismo naukowe
Tytuł:
Optimizing the Long-Term Therapy with Eculizumab (ECU) for Atypical Hemolytic Uremic Syndrome (aHUS).
Autorzy:
Santangelo L; Unit of Pediatric Nephrology, University Hospital 'Policlinico Consorziale - Giovanni XXIII', Bari, Italy.
Netti GS; Unit of Clinical Pathology, Advanced Research Center on Kidney Aging (A.R.K.A.), Department of Medical and Surgical Sciences, University of Foggia, Viale Luigi Pinto, 71122, Foggia, Italy. .
Mazza S; Unit of Pediatric Nephrology, University Hospital 'Policlinico Consorziale - Giovanni XXIII', Bari, Italy.
Zito F; Unit of Pediatric Nephrology, University Hospital 'Policlinico Consorziale - Giovanni XXIII', Bari, Italy.
Catalano V; Unit of Clinical Pathology, Advanced Research Center on Kidney Aging (A.R.K.A.), Department of Medical and Surgical Sciences, University of Foggia, Viale Luigi Pinto, 71122, Foggia, Italy.
Martino M; Unit of Pediatric Nephrology, University Hospital 'Policlinico Consorziale - Giovanni XXIII', Bari, Italy.
Torres DD; Unit of Pediatric Nephrology, University Hospital 'Policlinico Consorziale - Giovanni XXIII', Bari, Italy.
Carbone V; Unit of Pediatric Nephrology, University Hospital 'Policlinico Consorziale - Giovanni XXIII', Bari, Italy.
Ranieri E; Unit of Clinical Pathology, Advanced Research Center on Kidney Aging (A.R.K.A.), Department of Medical and Surgical Sciences, University of Foggia, Viale Luigi Pinto, 71122, Foggia, Italy.
Giordano M; Unit of Clinical Pathology, Advanced Research Center on Kidney Aging (A.R.K.A.), Department of Medical and Surgical Sciences, University of Foggia, Viale Luigi Pinto, 71122, Foggia, Italy.
Pokaż więcej
Źródło:
Indian journal of pediatrics [Indian J Pediatr] 2024 Feb; Vol. 91 (2), pp. 205. Date of Electronic Publication: 2023 Sep 30.
Typ publikacji:
Letter
MeSH Terms:
Atypical Hemolytic Uremic Syndrome*/drug therapy
Humans ; Antibodies, Monoclonal, Humanized/therapeutic use ; Complement Factor H
Opinia redakcyjna
Tytuł:
Defective C3d caused by C3 p.W1034R in inherited atypical hemolytic uremic syndrome.
Autorzy:
Tsuchida M; Division of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Goto S; Division of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Watanabe H; Division of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Goto S; Department of Applied Molecular Medicine, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Yamaguchi H; Division of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Narita I; Division of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Pokaż więcej
Źródło:
Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2024 Jan; Vol. 12 (1), pp. e2288. Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Journal Article
MeSH Terms:
Atypical Hemolytic Uremic Syndrome*/genetics
Humans ; Complement Factor H/genetics ; Mutation ; Complement System Proteins/genetics ; Genetic Testing
Czasopismo naukowe
Tytuł:
Genetic Variability of Complement Factor H Has Ethnicity-Specific Associations With Choroidal Thickness.
Autorzy:
Fenner BJ; Singapore National Eye Centre, Singapore.; Singapore Eye Research Institute, Singapore.
Li H; Singapore Eye Research Institute, Singapore.
Gan ATL; Singapore Eye Research Institute, Singapore.
Song YS; Singapore Eye Research Institute, Singapore.; Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.
Tham YC; Singapore Eye Research Institute, Singapore.; Centre for Innovation & Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore.
Jonas JB; Institute of Molecular and Clinical Ophthalmology, Basel, Switzerland.
Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Cheng CY; Singapore Eye Research Institute, Singapore.; Centre for Innovation & Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore.
Wong TY; School of Medicine, Tsinghua University, Beijing, China.
Teo KYC; Singapore National Eye Centre, Singapore.; Singapore Eye Research Institute, Singapore.
Tan ACS; Singapore National Eye Centre, Singapore.; Singapore Eye Research Institute, Singapore.
Fan Q; Singapore Eye Research Institute, Singapore.; Center for Quantitative Medicine, Duke-NUS Graduate Medical School, Singapore.
Cheung CMG; Singapore National Eye Centre, Singapore.; Singapore Eye Research Institute, Singapore.
Pokaż więcej
Źródło:
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2023 Feb 01; Vol. 64 (2), pp. 10.
Typ publikacji:
Journal Article
MeSH Terms:
Complement Factor H*/genetics
Macular Degeneration*/genetics
Humans ; Ethnicity ; Choroid/pathology ; Retina/pathology ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł:
The Factor H protein family: The switchers of the complement alternative pathway.
Autorzy:
Lucientes-Continente L; Department of Immunology, Ophthalmology and ENT, School of Medicine, Complutense University and Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain.
Márquez-Tirado B; Department of Immunology, Ophthalmology and ENT, School of Medicine, Complutense University and Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain.
Goicoechea de Jorge E; Department of Immunology, Ophthalmology and ENT, School of Medicine, Complutense University and Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain.
Pokaż więcej
Źródło:
Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 25-45. Date of Electronic Publication: 2022 Nov 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Complement Factor H*/metabolism
Complement System Proteins*/metabolism
Humans ; Complement Activation ; Complement Pathway, Alternative
Czasopismo naukowe
Tytuł:
Complement factor H variants are associated with microangiopathy lesions in IgA nephropathy.
Autorzy:
Hou W; Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China. Electronic address: .
Shi S; Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.
Zhou X; Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.
Wang S; Electron Microscopy Laboratory, Peking University First Hospital, Beijing, China.
Cai Q; Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.
Chen P; Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.
Liu L; Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.
Zhu L; Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.
Lv J; Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.
Zhang H; Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.
Pokaż więcej
Źródło:
International immunopharmacology [Int Immunopharmacol] 2022 Nov; Vol. 112, pp. 109234. Date of Electronic Publication: 2022 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Complement Factor H*/genetics
Complement Factor H*/metabolism
Glomerulonephritis, IGA*/pathology
Humans ; Genome-Wide Association Study ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł:
A supernumerary synthetic chromosome in Komagataella phaffii as a repository for extraneous genetic material.
Autorzy:
Abramczyk D; School of Chemistry, University of Edinburgh, Edinburgh, UK. .
Del Carmen Sanchez Olmos M; Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Rojas AAR; Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Schindler D; Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.; Center for Synthetic Microbiology, Philipps-Universität Marburg, Marburg, Germany.
Robertson D; School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
McColm S; Ingenza Ltd Scotland, Edinburgh, UK.
Marston AL; The Wellcome Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
Barlow PN; School of Chemistry, University of Edinburgh, Edinburgh, UK. .; School of Biological Sciences, University of Edinburgh, Edinburgh, UK. .
Pokaż więcej
Źródło:
Microbial cell factories [Microb Cell Fact] 2023 Dec 16; Vol. 22 (1), pp. 259. Date of Electronic Publication: 2023 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
Pichia*/genetics
Pichia*/metabolism
Saccharomycetales*/genetics
Humans ; Animals ; Mice ; Complement Factor H/genetics ; Complement Factor H/metabolism ; Homologous Recombination ; Chromosomes
SCR Organism:
Komagataella phaffii
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies