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Podgląd okładki
Tytuł :
Identification of post-digestion angiotensin-I converting enzyme (ACE) inhibitory peptides from soybean protein Isolate: Their production conditions and in silico molecular docking with ACE.
Autorzy :
Xu Z; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China; Guangdong Huapeptide Biotechnology Co., Ltd., Zhaoqing 526238, China.
Wu C; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China; Department of Food Science and Engineering, Jinan University, Guangzhou 510632, China.
Sun-Waterhouse D; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.
Zhao T; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.
Waterhouse GIN; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.
Zhao M; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China; Department of Food Science and Engineering, Jinan University, Guangzhou 510632, China; Guangdong Huapeptide Biotechnology Co., Ltd., Zhaoqing 526238, China.
Su G; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China; Department of Food Science and Engineering, Jinan University, Guangzhou 510632, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 May 30; Vol. 345, pp. 128855. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Digestion*
Molecular Docking Simulation*
Angiotensin-Converting Enzyme Inhibitors/*analysis
Peptides/*analysis
Peptidyl-Dipeptidase A/*metabolism
Soybean Proteins/*chemistry
Angiotensin-Converting Enzyme Inhibitors/metabolism ; Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Animals ; Hydrophobic and Hydrophilic Interactions ; Peptides/metabolism ; Peptides/pharmacology ; Peptidyl-Dipeptidase A/chemistry ; Protein Conformation
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Nonlinear adaptive control of COVID-19 with media campaigns and treatment.
Autorzy :
Cao B; Xinhua College, Ningxia University, Yinchuan, 750021, China; School of Mathematics, Southeast University, Nanjing, 211189, China. Electronic address: .
Kang T; Xinhua College, Ningxia University, Yinchuan, 750021, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 May 28; Vol. 555, pp. 202-209. Date of Electronic Publication: 2021 Jan 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Computer Simulation*
Nonlinear Dynamics*
COVID-19/*drug therapy
COVID-19/*prevention & control
Mass Media/*supply & distribution
COVID-19/epidemiology ; COVID-19/transmission ; Goals ; Humans ; Time Factors ; Uncertainty
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Modelling optimal vaccination strategy for SARS-CoV-2 in the UK.
Autorzy :
Moore S; The Zeeman Institute for Systems Biology & Infectious Disease Epidemiology Research, School of Life Sciences and Mathematics Institute, University of Warwick, Coventry, United Kingdom.
Hill EM; The Zeeman Institute for Systems Biology & Infectious Disease Epidemiology Research, School of Life Sciences and Mathematics Institute, University of Warwick, Coventry, United Kingdom.
Dyson L; The Zeeman Institute for Systems Biology & Infectious Disease Epidemiology Research, School of Life Sciences and Mathematics Institute, University of Warwick, Coventry, United Kingdom.
Tildesley MJ; The Zeeman Institute for Systems Biology & Infectious Disease Epidemiology Research, School of Life Sciences and Mathematics Institute, University of Warwick, Coventry, United Kingdom.
Keeling MJ; The Zeeman Institute for Systems Biology & Infectious Disease Epidemiology Research, School of Life Sciences and Mathematics Institute, University of Warwick, Coventry, United Kingdom.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2021 May 06; Vol. 17 (5), pp. e1008849. Date of Electronic Publication: 2021 May 06 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Computer Simulation*
Vaccination*
COVID-19/*immunology
COVID-19 Vaccines/*administration & dosage
COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/transmission ; Communicable Disease Control ; Humans ; Immunity, Herd ; United Kingdom/epidemiology
Czasopismo naukowe
Szczegóły Pełny tekst
Podgląd okładki
Tytuł :
Minimizing Population Health Loss in Times of Scarce Surgical Capacity During the Coronavirus Disease 2019 Crisis and Beyond: A Modeling Study.
Autorzy :
Gravesteijn B; Department of Otorhinolaryngology (ENT), Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands.
Krijkamp E; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Institute for Health Sciences, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address: .
Busschbach J; Department of Medical Psychology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Institute for Health Sciences, Erasmus University Medical Center, Rotterdam, The Netherlands.
Geleijnse G; Department of Otorhinolaryngology (ENT), Erasmus University Medical Center, Rotterdam, The Netherlands.
Helmrich IR; Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands.
Bruinsma S; Department of Quality and Patient Care, Erasmus University Medical Center, Rotterdam, The Netherlands.
van Lint C; Department of Quality and Patient Care, Erasmus University Medical Center, Rotterdam, The Netherlands.
van Veen E; Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Intensive Care, Erasmus University Medical Center, Rotterdam, The Netherlands.
Steyerberg E; Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Biostatistics, Leiden University Medical Center, Leiden, The Netherlands.
Verhoef K; Department of Surgical Oncology and Gastrointestinal Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.
van Saase J; Department of Internal Medicine - Erasmus University Medical Center, Rotterdam, The Netherlands.
Lingsma H; Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands.
Baatenburg de Jong R; Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands.
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Corporate Authors :
Value Based Operation Room Triage team collaborators
Źródło :
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research [Value Health] 2021 May; Vol. 24 (5), pp. 648-657. Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Computer Simulation*
COVID-19/*complications
Population Health/*statistics & numerical data
Surge Capacity/*standards
Cohort Studies ; Global Burden of Disease ; Humans ; Life Expectancy/trends ; Probability Theory ; Quality-Adjusted Life Years ; Surge Capacity/statistics & numerical data
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Simulation as a Dynamic Tool to Reorganize Pediatric Emergency Department Resuscitation During the Coronavirus Disease 2019 Pandemic and Beyond.
Autorzy :
Lavoie ME; From the Division of Emergency Medicine Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania.
Tay KY; From the Division of Emergency Medicine Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania.
Good G; Center for Simulation, Advanced Education, and Innovation.
Buchhalter L; Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
Abbadessa MK; Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
Gaines S; Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
Myers S; From the Division of Emergency Medicine Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania.
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Źródło :
Pediatric emergency care [Pediatr Emerg Care] 2021 May 01; Vol. 37 (5), pp. 286-289.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Pandemics*
COVID-19/*therapy
Emergency Service, Hospital/*organization & administration
Health Personnel/*organization & administration
Personal Protective Equipment/*supply & distribution
Resuscitation/*methods
COVID-19/epidemiology ; Child ; Humans
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Potential impact of COVID-19 on ongoing clinical trials: a simulation study with the neurological Yale Global Tic Severity Scale based on the CANNA-TICS study.
Autorzy :
Lasch F; Hannover Medical School, Hannover, Germany.
Guizzaro L; European Medicines Agency, Amsterdam, Netherlands.; Università della Campania, Naples, Italy.
Aguirre Dávila L; Paul-Ehrlich-Institut, Langen, Germany.
Müller-Vahl K; Hannover Medical School, Hannover, Germany.
Koch A; Hannover Medical School, Hannover, Germany.
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Źródło :
Pharmaceutical statistics [Pharm Stat] 2021 May; Vol. 20 (3), pp. 675-691. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Computer Simulation*
Mental Health*
Physical Distancing*
Randomized Controlled Trials as Topic*/statistics & numerical data
Research Design*/statistics & numerical data
COVID-19/*prevention & control
Cannabidiol/*therapeutic use
Dronabinol/*therapeutic use
Tic Disorders/*drug therapy
Tics/*drug therapy
COVID-19/psychology ; COVID-19/transmission ; Cannabidiol/adverse effects ; Data Interpretation, Statistical ; Dronabinol/adverse effects ; Drug Combinations ; Endpoint Determination ; Humans ; Sample Size ; Severity of Illness Index ; Tic Disorders/diagnosis ; Tic Disorders/psychology ; Tics/diagnosis ; Tics/psychology ; Time Factors ; Tourette Syndrome/drug therapy ; Tourette Syndrome/psychology ; Treatment Outcome
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
In-silico screening of database for finding potential sweet molecules: A combined data and structure based modeling approach.
Autorzy :
Goel A; Physical Sciences Research Area, Tata Research Development and Design Centre, Tata Consultancy Services, 54 B, Hadapsar Industrial Estate, Pune 411013, India.
Gajula K; Physical Sciences Research Area, Tata Research Development and Design Centre, Tata Consultancy Services, 54 B, Hadapsar Industrial Estate, Pune 411013, India.
Gupta R; Physical Sciences Research Area, Tata Research Development and Design Centre, Tata Consultancy Services, 54 B, Hadapsar Industrial Estate, Pune 411013, India. Electronic address: .
Rai B; Physical Sciences Research Area, Tata Research Development and Design Centre, Tata Consultancy Services, 54 B, Hadapsar Industrial Estate, Pune 411013, India.
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Źródło :
Food chemistry [Food Chem] 2021 May 01; Vol. 343, pp. 128538. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Databases, Pharmaceutical*
Molecular Docking Simulation*
Sweetening Agents/*chemistry
Sweetening Agents/*metabolism
Binding Sites ; Humans ; Receptors, G-Protein-Coupled/metabolism ; Structure-Activity Relationship ; Sweetening Agents/pharmacology
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19.
Autorzy :
Ge Y; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.; NHC Key laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, Jiangsu Province, China.
Tian T; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.; NHC Key laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, Jiangsu Province, China.
Huang S; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Wan F; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.
Li J; NHC Key laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, Jiangsu Province, China.
Li S; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.
Wang X; Silexon AI Technology Co., Ltd., Nanjing, Jiangsu Province, China.
Yang H; Silexon AI Technology Co., Ltd., Nanjing, Jiangsu Province, China.
Hong L; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.
Wu N; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.
Yuan E; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.
Luo Y; Department of Computer Science, University of Illinois at Urbana-Champaign, Illinois, IL, USA.
Cheng L; School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
Hu C; School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
Lei Y; Silexon AI Technology Co., Ltd., Nanjing, Jiangsu Province, China.
Shu H; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.
Feng X; School of Electronic Information and Communications, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.; Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Jiang Z; Department of Automation, Tsinghua University, Beijing, China.
Wu Y; Inner Mongolia Alashan League Organization Establishment Committee Office Electronic Support Center, Alashan, Inner Mongolia, China.
Chi Y; NHC Key laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, Jiangsu Province, China.
Guo X; NHC Key laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, Jiangsu Province, China.
Cui L; NHC Key laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, Jiangsu Province, China.
Xiao L; Convalife (Shanghai) Co., Ltd., Shanghai, China.
Li Z; Convalife (Shanghai) Co., Ltd., Shanghai, China.
Yang C; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Miao Z; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Chen L; School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Li H; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China.
Zeng H; Silexon AI Technology Co., Ltd., Nanjing, Jiangsu Province, China.
Zhao D; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China. .
Zhu F; NHC Key laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, Jiangsu Province, China. .; Center for Global Health, Nanjing Medical University, Nanjing, Jiangsu Province, China. .
Shen X; Convalife (Shanghai) Co., Ltd., Shanghai, China. .
Zeng J; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China. .
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Źródło :
Signal transduction and targeted therapy [Signal Transduct Target Ther] 2021 Apr 24; Vol. 6 (1), pp. 165. Date of Electronic Publication: 2021 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Computer Simulation*
Drug Repositioning*
Models, Biological*
Antiviral Agents/*therapeutic use
COVID-19/*drug therapy
COVID-19/*metabolism
SARS-CoV-2/*metabolism
Humans
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Implementation of a Six-Layer Smart Factory Architecture with Special Focus on Transdisciplinary Engineering Education.
Autorzy :
Ralph BJ; Chair of Metal Forming, Montanuniversität Leoben, Franz Josef Str. 18, 8700 Leoben, Austria.
Sorger M; Chair of Metal Forming, Montanuniversität Leoben, Franz Josef Str. 18, 8700 Leoben, Austria.
Schödinger B; Chair of Metal Forming, Montanuniversität Leoben, Franz Josef Str. 18, 8700 Leoben, Austria.
Schmölzer HJ; Chair of Metal Forming, Montanuniversität Leoben, Franz Josef Str. 18, 8700 Leoben, Austria.
Hartl K; Chair of Metal Forming, Montanuniversität Leoben, Franz Josef Str. 18, 8700 Leoben, Austria.
Stockinger M; Chair of Metal Forming, Montanuniversität Leoben, Franz Josef Str. 18, 8700 Leoben, Austria.
Pokaż więcej
Źródło :
Sensors (Basel, Switzerland) [Sensors (Basel)] 2021 Apr 22; Vol. 21 (9). Date of Electronic Publication: 2021 Apr 22.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Education*
Humans ; Workflow
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Development of an In Vivo Predictive Dissolution Methodology of Topiroxostat Immediate-Release Tablet Using In Silico Simulation.
Autorzy :
Li G; Beijing Adamadle Biotech Co., Ltd., Beijing, 100102, People's Republic of China.
Yang H; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Sunshine South Street, Fangshan District, Beijing, 100102, People's Republic of China.
Liu W; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Sunshine South Street, Fangshan District, Beijing, 100102, People's Republic of China.
Shen C; Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China.
Ji Y; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Sunshine South Street, Fangshan District, Beijing, 100102, People's Republic of China.
Sun Y; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Sunshine South Street, Fangshan District, Beijing, 100102, People's Republic of China.
Huo Q; Department of Biomedical, Beijing Union University College of Health and Environment, Chaoyang District, Beijing, 100023, People's Republic of China. .
Liu Y; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Sunshine South Street, Fangshan District, Beijing, 100102, People's Republic of China. .
Wang G; Zhongcai Health (Beijing) Biological Technology Development Co., Ltd., Beijing, 101500, People's Republic of China.
Pokaż więcej
Źródło :
AAPS PharmSciTech [AAPS PharmSciTech] 2021 Apr 13; Vol. 22 (3), pp. 132. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Computer Simulation*
Models, Biological*
Nitriles/*chemistry
Nitriles/*pharmacokinetics
Pyridines/*chemistry
Pyridines/*pharmacokinetics
Adult ; Drug Liberation/physiology ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacokinetics ; Female ; Forecasting ; Humans ; Linear Models ; Male ; Middle Aged ; Tablets ; Young Adult
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Identification of Vinyl Sulfone Derivatives as EGFR Tyrosine Kinase Inhibitor: In Vitro and In Silico Studies.
Autorzy :
Aiebchun T; Biocatalyst and Environmental Biotechnology Research Unit, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Mahalapbutr P; Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Auepattanapong A; Department of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Bangkok 10700, Thailand.
Khaikate O; Department of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Bangkok 10700, Thailand.
Seetaha S; Department of Biochemistry, Faculty of Science, Kasetsart University, Chatuchak, Bangkok 10900, Thailand.
Tabtimmai L; Department of Biotechnology, Faculty of Applied Science, King Mongkut's University of Technology of North Bangkok, Bangkok 10800, Thailand.
Kuhakarn C; Department of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Bangkok 10700, Thailand.
Choowongkomon K; Department of Biochemistry, Faculty of Science, Kasetsart University, Chatuchak, Bangkok 10900, Thailand.
Rungrotmongkol T; Biocatalyst and Environmental Biotechnology Research Unit, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.; Program in Bioinformatics and Computational Biology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Pokaż więcej
Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 12; Vol. 26 (8). Date of Electronic Publication: 2021 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
ErbB Receptors/*antagonists & inhibitors
Protein Kinase Inhibitors/*pharmacology
Sulfones/*pharmacology
Cell Death/drug effects ; Cell Line, Tumor ; ErbB Receptors/metabolism ; Erlotinib Hydrochloride/chemistry ; Erlotinib Hydrochloride/pharmacology ; Humans ; Hydrogen Bonding ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Protein Kinase Inhibitors/chemistry ; Sulfones/chemistry ; Thermodynamics
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Exosomal Aβ-Binding Proteins Identified by "In Silico" Analysis Represent Putative Blood-Derived Biomarker Candidates for Alzheimer´s Disease.
Autorzy :
Soares Martins T; Neurosciences and Signalling Group, Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro (UA), 3810-193 Aveiro, Portugal.
Marçalo R; Neurosciences and Signalling Group, Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro (UA), 3810-193 Aveiro, Portugal.
Ferreira M; Neurosciences and Signalling Group, Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro (UA), 3810-193 Aveiro, Portugal.
Vaz M; Neurosciences and Signalling Group, Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro (UA), 3810-193 Aveiro, Portugal.
Silva RM; Center for Interdisciplinary Research in Health (CIIS), Faculdade de Medicina Dentária, Universidade Católica Portuguesa, Estrada da Circunvalação, 3504-505 Viseu, Portugal.
Martins Rosa I; Neurosciences and Signalling Group, Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro (UA), 3810-193 Aveiro, Portugal.
Vogelgsang J; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen (UMG), Georg-August University, Von-Siebold-Str. 5, 37075 Goettingen, Germany.; Translational Neuroscience Laboratory, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA.
Wiltfang J; Neurosciences and Signalling Group, Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro (UA), 3810-193 Aveiro, Portugal.; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen (UMG), Georg-August University, Von-Siebold-Str. 5, 37075 Goettingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Von-Siebold-Str. 3a, 37075 Goettingen, Germany.
da Cruz E Silva OAB; Neurosciences and Signalling Group, Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro (UA), 3810-193 Aveiro, Portugal.
Henriques AG; Neurosciences and Signalling Group, Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro (UA), 3810-193 Aveiro, Portugal.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 11; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 11.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Databases, Protein*
Alzheimer Disease/*blood
Amyloid beta-Peptides/*blood
Exosomes/*metabolism
Biomarkers/blood ; Female ; Humans ; Male
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Reducing Bias Due to Exposure Measurement Error Using Disease Risk Scores.
Autorzy :
Richardson DB
Keil AP
Cole SR
Edwards JK
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Źródło :
American journal of epidemiology [Am J Epidemiol] 2021 Apr 06; Vol. 190 (4), pp. 621-629.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Computer Simulation*
Models, Statistical*
Disease Susceptibility/*epidemiology
Risk Assessment/*statistics & numerical data
Bias ; Humans ; Risk Factors
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Common Methods for Handling Missing Data in Marginal Structural Models: What Works and Why.
Autorzy :
Leyrat C
Carpenter JR
Bailly S
Williamson EJ
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Źródło :
American journal of epidemiology [Am J Epidemiol] 2021 Apr 06; Vol. 190 (4), pp. 663-672.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Computer Simulation*
Models, Statistical*
Electronic Health Records/*statistics & numerical data
Data Interpretation, Statistical ; Humans
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Therapeutic Potential of Tuna Backbone Peptide and Its Analogs: An In Vitro and In Silico Study.
Autorzy :
Gopinatth V; Department of Integrative Biology, Oregon State University, Corvallis, OR 97331, USA.
Mendez RL; Department of Food Science and Technology, Oregon State University, Corvallis, OR 97331, USA.
Ballinger E; Department of Food Science and Technology, Oregon State University, Corvallis, OR 97331, USA.; Seafood Research and Education Center, Oregon State University, Astoria, OR 97103, USA.
Kwon JY; Department of Food Science and Technology, Oregon State University, Corvallis, OR 97331, USA.; Seafood Research and Education Center, Oregon State University, Astoria, OR 97103, USA.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 03; Vol. 26 (7). Date of Electronic Publication: 2021 Apr 03.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Peptides/*therapeutic use
Tuna/*metabolism
Amino Acid Sequence ; Animals ; Antioxidants/pharmacology ; Hydrolysis ; Peptides/chemistry ; Protein Stability
Czasopismo naukowe
Szczegóły Pełny tekst
Podgląd okładki
Tytuł :
Synergizing Off-Target Predictions for In Silico Insights of CENH3 Knockout in Cannabis through CRISPR/Cas.
Autorzy :
Hesami M; Department of Plant Agriculture, University of Guelph, Guelph, ON N1G 2W1, Canada.
Yoosefzadeh Najafabadi M; Department of Plant Agriculture, University of Guelph, Guelph, ON N1G 2W1, Canada.
Adamek K; Department of Plant Agriculture, University of Guelph, Guelph, ON N1G 2W1, Canada.
Torkamaneh D; Department of Plant Agriculture, University of Guelph, Guelph, ON N1G 2W1, Canada.; Département de Phytologie, Université Laval, Québec City, QC G1V 0A6, Canada.
Jones AMP; Department of Plant Agriculture, University of Guelph, Guelph, ON N1G 2W1, Canada.
Pokaż więcej
Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 03; Vol. 26 (7). Date of Electronic Publication: 2021 Apr 03.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Gene Knockout Techniques*
CRISPR-Cas Systems/*genetics
Cannabis/*genetics
Centromere/*metabolism
Histones/*genetics
Area Under Curve ; ROC Curve ; Support Vector Machine
Czasopismo naukowe
Szczegóły Pełny tekst
Podgląd okładki
Tytuł :
Isolation, Structure Elucidation and In Silico Prediction of Potential Drug-Like Flavonoids from Onosma chitralicum Targeted towards Functionally Important Proteins of Drug-Resistant Bad Bugs.
Autorzy :
Khan SA; Department of Chemistry, Kohat University of Science & Technology, Kohat 26000, Pakistan.
Khan SU; School of Pharmacy, Monash University, Bandar Sunway, Subang Jaya 47500, Malaysia.; Department of Pharmacy, Abasyn University, Ring Road, Peshawar 25120, Pakistan.
Fozia; Biochemistry Department, KMU Institute of Medical Sciences, Kohat 26000, Pakistan.
Ullah N; Department of Biochemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.
Shah M; Department of Biochemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.
Ullah R; Department of Pharmacognosy, College of Pharmacy, King Saud University Riyadh Saudi Arabia, Riyadh 11495, Saudi Arabia.
Ahmad I; Department of Chemistry, Kohat University of Science & Technology, Kohat 26000, Pakistan.
Alotaibi A; Basic Science Department, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 02; Vol. 26 (7). Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Drug Resistance, Bacterial*/drug effects
Bacterial Proteins/*antagonists & inhibitors
Boraginaceae/*chemistry
Flavonoids/*chemistry
Flavonoids/*isolation & purification
Salmonella typhi/*drug effects
Staphylococcus aureus/*drug effects
Antifungal Agents/chemistry ; Antifungal Agents/pharmacology ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Binding Sites ; Drug Evaluation, Preclinical ; Flavonoids/pharmacology ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Salmonella typhi/metabolism ; Staphylococcus aureus/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Szczegóły Pełny tekst
Podgląd okładki
Tytuł :
A Data-Driven Simulation of the Exposure Notification Cascade for Digital Contact Tracing of SARS-CoV-2 in Zurich, Switzerland.
Autorzy :
Menges D; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Aschmann HE; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Moser A; CTU Bern, University of Bern, Bern, Switzerland.
Althaus CL; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
von Wyl V; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.; Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.
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Źródło :
JAMA network open [JAMA Netw Open] 2021 Apr 01; Vol. 4 (4), pp. e218184. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/diagnosis
COVID-19*/epidemiology
COVID-19*/prevention & control
COVID-19*/transmission
Computer Simulation*
Contact Tracing*/methods
Contact Tracing*/statistics & numerical data
Disease Notification*/methods
Disease Notification*/statistics & numerical data
Disease Transmission, Infectious*/prevention & control
Disease Transmission, Infectious*/statistics & numerical data
Mobile Applications*
Adult ; Communicable Disease Control/methods ; Communicable Disease Control/organization & administration ; Female ; Humans ; Male ; Quarantine ; SARS-CoV-2/isolation & purification ; Switzerland/epidemiology
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
A unified framework for cross-population trait prediction by leveraging the genetic correlation of polygenic traits.
Autorzy :
Cai M; Guangzhou HKUST Fok Ying Tung Research Institute, Guangzhou 511458, China; Department of Mathematics, The Hong Kong University of Science and Technology, Hong Kong SAR, China.
Xiao J; Guangzhou HKUST Fok Ying Tung Research Institute, Guangzhou 511458, China; Department of Mathematics, The Hong Kong University of Science and Technology, Hong Kong SAR, China.
Zhang S; Guangzhou HKUST Fok Ying Tung Research Institute, Guangzhou 511458, China; Department of Mathematics, The Hong Kong University of Science and Technology, Hong Kong SAR, China.
Wan X; Shenzhen Research Institute of Big Data, Shenzhen 518172, China.
Zhao H; SJTU-Yale Joint Center for Biostatistics and Data Science, Shanghai Jiao Tong University, Shanghai 201111, China; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA.
Chen G; Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha 410083, China. Electronic address: .
Yang C; Guangzhou HKUST Fok Ying Tung Research Institute, Guangzhou 511458, China; Department of Mathematics, The Hong Kong University of Science and Technology, Hong Kong SAR, China. Electronic address: .
Pokaż więcej
Źródło :
American journal of human genetics [Am J Hum Genet] 2021 Apr 01; Vol. 108 (4), pp. 632-655. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Body Mass Index*
Computer Simulation*
Models, Genetic*
Body Height/*genetics
Multifactorial Inheritance/*genetics
Africa/ethnology ; African Continental Ancestry Group/genetics ; Asian Continental Ancestry Group/genetics ; China/ethnology ; Databases, Factual ; Female ; Genome-Wide Association Study ; Humans ; Male ; Principal Component Analysis ; Sample Size ; United Kingdom
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 522403

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