Temat: "Connexin 43" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: C‑type natriuretic peptide prevents angiotensin II‑induced atrial connexin 40 and 43 dysregulation by activating AMP‑activated kinase signaling.
Autorzy:: Ding DZ; Department of Cardiology, Institute of Clinical Medicine, Yanbian University, Yanji, Jilin 133002, P.R. China.
Jia YN; Department of Cardiology, Institute of Clinical Medicine, Yanbian University, Yanji, Jilin 133002, P.R. China.
Zhang B; Department of Physiology, College of Medicine, Yanbian University, Yanji, Jilin 133002, P.R. China.
Guan CM; Department of Cardiology, Institute of Clinical Medicine, Yanbian University, Yanji, Jilin 133002, P.R. China.
Zhou S; Department of Physiology, College of Medicine, Yanbian University, Yanji, Jilin 133002, P.R. China.
Li X; Department of Physiology, College of Medicine, Yanbian University, Yanji, Jilin 133002, P.R. China.
Cui X; Department of Physiology, College of Medicine, Yanbian University, Yanji, Jilin 133002, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2019 Dec; Vol. 20 (6), pp. 5091-5099. Date of Electronic Publication: 2019 Oct 15.
Typ publikacji:: Journal Article
MeSH Terms:: AMP-Activated Protein Kinases/*metabolism
Angiotensin II/*metabolism
Connexin 43/*genetics
Connexins/*genetics
Heart Atria/*metabolism
Natriuretic Peptide, C-Type/*metabolism
Signal Transduction/*genetics
Angiotensin II/pharmacology ; Animals ; Biomarkers ; Connexin 43/metabolism ; Connexins/metabolism ; Female ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fibrosis ; Gene Expression Regulation/drug effects ; Heart Atria/drug effects ; Heart Atria/pathology ; Male ; Natriuretic Peptide, C-Type/pharmacology ; Rats ; Signal Transduction/drug effects ; Transforming Growth Factor beta1/genetics ; Transforming Growth Factor beta1/metabolism ; Gap Junction alpha-5 Protein

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Skocz do pozycji: 2.

Tytuł:: Complex role of connexin 43 in astrocytic tumors and possible promotion of glioma‑associated epileptic discharge (Review).
Autorzy:: Dong H; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Zhou XW; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Wang X; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Yang Y; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Luo JW; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Liu YH; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Mao Q; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2017 Dec; Vol. 16 (6), pp. 7890-7900. Date of Electronic Publication: 2017 Sep 26.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Astrocytoma/*etiology
Astrocytoma/*metabolism
Connexin 43/*metabolism
Epilepsy/*etiology
Glioma/*complications
Glioma/*metabolism
Animals ; Astrocytoma/diagnosis ; Astrocytoma/therapy ; Cell Movement ; Cell Proliferation ; Connexin 43/chemistry ; Connexin 43/genetics ; Epilepsy/physiopathology ; Gene Expression Regulation, Neoplastic ; Glioma/diagnosis ; Glioma/therapy ; Humans ; Neoplasm Grading ; Structure-Activity Relationship

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Skocz do pozycji: 3.

Tytuł:: Carbenoxolone has the potential to ameliorate acute incision pain in rats.
Autorzy:: Dong S; Department of Anesthesiology, The Second Hospital of Lanzhou University, Lanzhou, Gansu 730030, P.R. China.
Zhang K; Department of Anesthesiology, The Second Hospital of Lanzhou University, Lanzhou, Gansu 730030, P.R. China.
Shi Y; Department of Anesthesiology, The Second Hospital of Lanzhou University, Lanzhou, Gansu 730030, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Jul; Vol. 24 (1). Date of Electronic Publication: 2021 May 20.
Typ publikacji:: Journal Article
MeSH Terms:: Acute Pain/*drug therapy
Acute Pain/*metabolism
Carbenoxolone/*pharmacology
Acute Pain/genetics ; Animals ; Astrocytes/metabolism ; Connexin 43/genetics ; Connexin 43/metabolism ; Connexins/genetics ; Connexins/metabolism ; Disease Models, Animal ; Glial Fibrillary Acidic Protein/metabolism ; Hyperalgesia/metabolism ; Male ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Rats ; Rats, Sprague-Dawley

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Skocz do pozycji: 4.

Tytuł:: Inflammatory response in epilepsy is mediated by glial cell gap junction pathway (Review).
Autorzy:: Wang G; Department of Cardiology, Dalinghe Hospital of Far Eastern Horizon, Linghai, Liaoning 121200, P.R. China.
Wang J; Department of Pediatric Neurology, Jilin University, Changchun, Jilin 130000, P.R. China.
Xin C; Department of Pediatric Neurology, Jilin University, Changchun, Jilin 130000, P.R. China.
Xiao J; Department of Pediatric Neurology, Jilin University, Changchun, Jilin 130000, P.R. China.
Liang J; Department of Pediatric Neurology, Jilin University, Changchun, Jilin 130000, P.R. China.
Wu X; Department of Pediatric Neurology, Jilin University, Changchun, Jilin 130000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Jul; Vol. 24 (1). Date of Electronic Publication: 2021 May 06.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Epilepsy/*etiology
Epilepsy/*metabolism
Gap Junctions/*metabolism
Inflammation/*metabolism
Neuroglia/*metabolism
Adenosine Triphosphate/metabolism ; Animals ; Astrocytes/metabolism ; Central Nervous System/metabolism ; Connexin 43/metabolism ; Humans

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Skocz do pozycji: 5.

Tytuł:: Tumor suppressor miR‑613 induces cisplatin sensitivity in non‑small cell lung cancer cells by targeting GJA1.
Autorzy:: Luo J; Department of Respiratory Medicine, Taizhou Municipal Hospital, Taizhou, Zhejiang 318000, P.R. China.
Jin Y; Department of Respiratory Medicine, Taizhou Municipal Hospital, Taizhou, Zhejiang 318000, P.R. China.
Li M; Department of Respiratory Medicine, Taizhou Municipal Hospital, Taizhou, Zhejiang 318000, P.R. China.
Dong L; Department of Invasive Technology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 May; Vol. 23 (5). Date of Electronic Publication: 2021 Mar 24.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung/*drug therapy
Connexin 43/*genetics
MicroRNAs/*genetics
A549 Cells ; Aged ; Apoptosis/genetics ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/drug effects ; Cisplatin/administration & dosage ; Cisplatin/adverse effects ; Drug Resistance, Neoplasm/genetics ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Male ; Middle Aged

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Skocz do pozycji: 6.

Tytuł:: Enhanced expression of Cx43 and gap junction communication in vascular smooth muscle cells of spontaneously hypertensive rats.
Autorzy:: Wang LJ; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Liu WD; Department of Gastroenterology, The People's Hospital of Xinjiang Uyghur Autonomous Region, Urumqi, Xinjiang 830001, P.R. China.
Zhang L; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Ma KT; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Zhao L; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Shi WY; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Zhang WW; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Wang YZ; The Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Li L; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Si JQ; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2016 Nov; Vol. 14 (5), pp. 4083-4090. Date of Electronic Publication: 2016 Sep 26.
Typ publikacji:: Journal Article
MeSH Terms:: Connexin 43/*biosynthesis
Hypertension/*drug therapy
Muscle, Smooth, Vascular/*drug effects
Niflumic Acid/*administration & dosage
Animals ; Blood Pressure/drug effects ; Connexin 43/genetics ; Disease Models, Animal ; Gap Junctions/drug effects ; Gap Junctions/pathology ; Gene Expression Regulation/drug effects ; Humans ; Hypertension/genetics ; Hypertension/pathology ; Mesenteric Arteries/drug effects ; Mesenteric Arteries/pathology ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/pathology ; Patch-Clamp Techniques ; Rats

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Skocz do pozycji: 7.

Tytuł:: Gap junction composed of connexin43 modulates 5‑fluorouracil, oxaliplatin and irinotecan resistance on colorectal cancers.
Autorzy:: Zou ZW; Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Chen HJ; Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Yu JL; Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Huang ZH; Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Fang S; Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Lin XH; Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2016 Nov; Vol. 14 (5), pp. 4893-4900. Date of Electronic Publication: 2016 Oct 06.
Typ publikacji:: Journal Article
MeSH Terms:: Drug Resistance, Neoplasm*/genetics
Antineoplastic Agents/*pharmacology
Camptothecin/*analogs & derivatives
Colorectal Neoplasms/*metabolism
Connexin 43/*metabolism
Fluorouracil/*pharmacology
Gap Junctions/*metabolism
Organoplatinum Compounds/*pharmacology
Camptothecin/pharmacology ; Cell Line, Tumor ; Cell Survival/drug effects ; Colorectal Neoplasms/genetics ; Connexin 43/genetics ; Gene Knockdown Techniques ; Humans ; Irinotecan ; Oxaliplatin

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Skocz do pozycji: 8.

Tytuł:: Phenotypic transformation of smooth muscle cells from porcine coronary arteries is associated with connexin 43.
Autorzy:: Zhang X; Department of Cardiology, East Hospital at Tongji University, Shanghai 200120, P.R. China.
Wang X; Department of Cardiology, East Hospital at Tongji University, Shanghai 200120, P.R. China.
Zhou X; Department of Cardiology, East Hospital at Tongji University, Shanghai 200120, P.R. China.
Ma X; Department of Cardiology, East Hospital at Tongji University, Shanghai 200120, P.R. China.
Yao Y; Department of Cardiology, East Hospital at Tongji University, Shanghai 200120, P.R. China.
Liu X; Department of Cardiology, East Hospital at Tongji University, Shanghai 200120, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2016 Jul; Vol. 14 (1), pp. 41-8. Date of Electronic Publication: 2016 May 13.
Typ publikacji:: Journal Article
MeSH Terms:: Phenotype*
Connexin 43/*metabolism
Coronary Vessels/*metabolism
Coronary Vessels/*pathology
Myocytes, Smooth Muscle/*metabolism
Myocytes, Smooth Muscle/*pathology
Animals ; Biomarkers ; Cells, Cultured ; Connexin 43/genetics ; Connexins/genetics ; Connexins/metabolism ; Coronary Restenosis/genetics ; Coronary Restenosis/metabolism ; Coronary Restenosis/pathology ; Coronary Restenosis/therapy ; Female ; Gene Expression ; Immunophenotyping ; Male ; Myocytes, Smooth Muscle/drug effects ; Platelet-Derived Growth Factor/metabolism ; Platelet-Derived Growth Factor/pharmacology ; Stents ; Swine

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Skocz do pozycji: 9.

Tytuł:: Propofol protects against oxygen/glucose deprivation‑induced cell injury via gap junction inhibition in astrocytes.
Autorzy:: Fan Y; Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong 510623, P.R. China.
Zhu S; Department of Medical Imaging, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat‑sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China.
Wang J; Department of Anesthesiology, State Key Laboratory of Oncology in South China, Sun Yat‑sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China.
Zhao Y; Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong 510623, P.R. China.
Wang X; Department of Anesthesiology, State Key Laboratory of Oncology in South China, Sun Yat‑sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2020 Oct; Vol. 22 (4), pp. 2896-2904. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji:: Journal Article
MeSH Terms:: Astrocytes/*drug effects
Astrocytes/*metabolism
Cell Hypoxia/*drug effects
Gap Junctions/*drug effects
Glucose/*metabolism
Oxygen/*metabolism
Propofol/*pharmacology
Protective Agents/*pharmacology
Animals ; Animals, Newborn ; Apoptosis/drug effects ; Apoptosis/genetics ; Cells, Cultured ; Connexin 43/genetics ; Connexin 43/metabolism ; Down-Regulation/drug effects ; Gap Junctions/metabolism ; Male ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/metabolism ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Stroke/metabolism ; Transfection

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Skocz do pozycji: 10.

Tytuł:: Angiotensin II induces RAW264.7 macrophage polarization to the M1-type through the connexin 43/NF-κB pathway.
Autorzy:: Wu, Lei (AUTHOR)
Chen, Kai (AUTHOR)
Xiao, Jingjie (AUTHOR)
Xin, Junzhou (AUTHOR)
Zhang, Liang (AUTHOR)
Li, Xinzhi (AUTHOR)
Li, Li (AUTHOR)
Si, Junqiang (AUTHOR)
Wang, Li (AUTHOR)
Ma, Ketao (AUTHOR); Pokaż więcej
Źródło:: Molecular Medicine Reports. May2020, Vol. 21 Issue 5, p2103-2112. 10p.

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Skocz do pozycji: 11.

Tytuł:: MG132 proteasome inhibitor upregulates the expression of connexin 43 in rats with adriamycin-induced heart failure.
Autorzy:: Chen G; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Zhao J; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Liu C; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Zhang Y; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Huo Y; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Zhou L; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2015 Nov; Vol. 12 (5), pp. 7595-602. Date of Electronic Publication: 2015 Sep 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibiotics, Antineoplastic/*toxicity
Cardiotonic Agents/*pharmacology
Connexin 43/*metabolism
Doxorubicin/*toxicity
Heart Failure/*prevention & control
Leupeptins/*pharmacology
Animals ; Connexin 43/genetics ; Drug Evaluation, Preclinical ; Gene Expression Regulation/drug effects ; Heart Failure/chemically induced ; Heart Failure/metabolism ; Male ; Proteasome Inhibitors/pharmacology ; Rats, Wistar ; Up-Regulation ; Ventricular Fibrillation/chemically induced ; Ventricular Fibrillation/metabolism ; Ventricular Fibrillation/prevention & control ; Zonula Occludens-1 Protein/genetics ; Zonula Occludens-1 Protein/metabolism

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Skocz do pozycji: 12.

Tytuł:: Effects of rotigaptide (ZP123) on connexin43 remodeling in canine ventricular fibrillation.
Autorzy:: Su GY; Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Wang J; Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Xu ZX; Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Qiao XJ; Department of Cardiology, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong 250012, P.R. China.
Zhong JQ; Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Zhang Y; Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2015 Oct; Vol. 12 (4), pp. 5746-52. Date of Electronic Publication: 2015 Aug 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Electric Countershock*
Anti-Arrhythmia Agents/*pharmacology
Connexin 43/*genetics
Gene Expression Regulation/*drug effects
Oligopeptides/*pharmacology
Ventricular Fibrillation/*drug therapy
Animals ; Cardiopulmonary Resuscitation ; Connexin 43/metabolism ; Diastole ; Dogs ; Electrocardiography ; Female ; Heart Ventricles/drug effects ; Heart Ventricles/metabolism ; Heart Ventricles/physiopathology ; Hemodynamics/drug effects ; Male ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Phosphorylation ; Systole ; Ventricular Fibrillation/genetics ; Ventricular Fibrillation/metabolism ; Ventricular Fibrillation/physiopathology

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Skocz do pozycji: 13.

Tytuł:: Suppression of PKCε-mediated mitochondrial connexin 43 phosphorylation at serine 368 is involved in myocardial mitochondrial dysfunction in a rat model of dilated cardiomyopathy.
Autorzy:: Shan H; Department of Cardiology, The Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi 710004, P.R. China.
Wei J; Department of Cardiology, The Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi 710004, P.R. China.
Zhang M; Department of Cardiology, The Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi 710004, P.R. China.
Lin L; Department of Cardiology, The Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi 710004, P.R. China.
Yan R; Department of Cardiology, The Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi 710004, P.R. China.
Zhang R; Department of Gastroenterology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China.
Zhu YH; Department of Cardiology, The Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi 710004, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2015 Jun; Vol. 11 (6), pp. 4720-6. Date of Electronic Publication: 2015 Jan 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cardiomyopathy, Dilated/*pathology
Connexin 43/*metabolism
Mitochondria, Heart/*metabolism
Protein Kinase C-epsilon/*metabolism
Administration, Oral ; Animals ; Cardiomyopathy, Dilated/drug therapy ; Cardiomyopathy, Dilated/metabolism ; Cells, Cultured ; Connexin 43/chemistry ; Disease Models, Animal ; Electron Transport Complex IV/metabolism ; Furazolidone/therapeutic use ; Glycyrrhetinic Acid/analogs & derivatives ; Glycyrrhetinic Acid/pharmacology ; Membrane Potential, Mitochondrial/drug effects ; Myocardium/metabolism ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Phosphorylation/drug effects ; Protein Kinase C-epsilon/chemistry ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Serine/metabolism ; Succinate Dehydrogenase/metabolism ; Tetradecanoylphorbol Acetate/pharmacology ; Transcription, Genetic/drug effects

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Skocz do pozycji: 14.

Tytuł:: Interactions of connexin 43 and aquaporin-4 in the formation of glioma-induced brain edema.
Autorzy:: Li G; Department of Neurosurgery, Tianjin 5th Center Hospital, Tianjin 300450, P.R. China.
Liu X; Department of Neurosurgery, Tianjin 5th Center Hospital, Tianjin 300450, P.R. China.
Liu Z; Department of Neurosurgery, Tianjin 5th Center Hospital, Tianjin 300450, P.R. China.
Su Z; Department of Neurosurgery, Tianjin 5th Center Hospital, Tianjin 300450, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2015 Feb; Vol. 11 (2), pp. 1188-94. Date of Electronic Publication: 2014 Nov 05.
Typ publikacji:: Journal Article
MeSH Terms:: Aquaporin 4/*metabolism
Brain Edema/*etiology
Brain Neoplasms/*pathology
Connexin 43/*metabolism
Glioma/*pathology
Animals ; Aquaporin 4/antagonists & inhibitors ; Aquaporin 4/genetics ; Brain Edema/diagnostic imaging ; Brain Neoplasms/complications ; Brain Neoplasms/diagnostic imaging ; Cell Line, Tumor ; Connexin 43/antagonists & inhibitors ; Connexin 43/genetics ; Glioma/complications ; Glioma/diagnostic imaging ; Magnetic Resonance Imaging ; Male ; Mice ; RNA Interference ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Radiography ; Rats ; Rats, Sprague-Dawley ; Transplantation, Heterologous

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Skocz do pozycji: 15.

Tytuł:: Involvement of connexin43 in the acute hyperosmotic stimulus‑induced synthesis and release of vasopressin in the supraoptic nucleus of rats.
Autorzy:: Jiang S; Department of Physical Medicine and Rehabilitation, The First Affiliated Hospital, Chinese PLA General Hospital, Beijing 100048, P.R. China.
Wang YQ; Department of Opthalmology, Jinan Military General Hospital, Jinan, Shandong 250031, P.R. China.
Xu CF; Department of Physical Medicine and Rehabilitation, The First Affiliated Hospital, Chinese PLA General Hospital, Beijing 100048, P.R. China.
Li YN; Department of Physical Medicine and Rehabilitation, The First Affiliated Hospital, Chinese PLA General Hospital, Beijing 100048, P.R. China.
Guo R; Department of Physical Medicine and Rehabilitation, The First Affiliated Hospital, Chinese PLA General Hospital, Beijing 100048, P.R. China.
Li L; Department of Physical Medicine and Rehabilitation, The First Affiliated Hospital, Chinese PLA General Hospital, Beijing 100048, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2014 Oct; Vol. 10 (4), pp. 2165-71. Date of Electronic Publication: 2014 Jul 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Osmotic Pressure*
Connexin 43/*metabolism
Supraoptic Nucleus/*metabolism
Vasopressins/*metabolism
Animals ; Calcium/metabolism ; Carbenoxolone/pharmacology ; Connexin 43/antagonists & inhibitors ; Connexin 43/genetics ; Gap Junctions/metabolism ; Male ; Oligodeoxyribonucleotides, Antisense/metabolism ; Peptides/pharmacology ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Up-Regulation/drug effects ; Vasopressins/genetics

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Skocz do pozycji: 16.

Tytuł:: β‑estradiol alleviates hypertension‑ and concanavalin A‑mediated inflammatory responses via modulation of connexins in peripheral blood lymphocytes.
Autorzy:: Ni X; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Zhang L; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Ma X; Department of Anesthesiology, First Affiliated Hospital, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Shan LY; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Li L; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Si JQ; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Li XZ; Department of Pathophysiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.
Zhang YY; Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, P.R. China.
Ma KT; Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2019 May; Vol. 19 (5), pp. 3743-3755. Date of Electronic Publication: 2019 Mar 14.
Typ publikacji:: Journal Article
MeSH Terms:: Concanavalin A/*adverse effects
Connexins/*metabolism
Estradiol/*pharmacology
Hypertension/*complications
Inflammation/*etiology
Inflammation/*metabolism
Lymphocytes/*drug effects
Lymphocytes/*metabolism
Animals ; Blood Pressure/drug effects ; Connexin 43/genetics ; Connexin 43/metabolism ; Connexins/genetics ; Cytokines/blood ; Cytokines/metabolism ; Gap Junctions/metabolism ; Gene Expression ; Hypertension/physiopathology ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Kidney/drug effects ; Kidney/metabolism ; Kidney/pathology ; Lymphocyte Activation/drug effects ; Male ; Rats ; Vascular Remodeling/drug effects

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Skocz do pozycji: 17.

Tytuł:: Changes in integrin αv, vinculin and connexin43 in the medial prefrontal cortex in rats under single-prolonged stress.
Autorzy:: Li Y; Department of Histology and Embryology, Institute of Pathology and Pathophysiology, Basic Medical Sciences College, China Medical University, Shenyang, Liaoning 110001, P.R. China.
Han F; Department of Histology and Embryology, Institute of Pathology and Pathophysiology, Basic Medical Sciences College, China Medical University, Shenyang, Liaoning 110001, P.R. China.
Shi Y; Department of Histology and Embryology, Institute of Pathology and Pathophysiology, Basic Medical Sciences College, China Medical University, Shenyang, Liaoning 110001, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2015 Apr; Vol. 11 (4), pp. 2520-6. Date of Electronic Publication: 2014 Dec 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Stress, Physiological*
Connexin 43/*genetics
Integrin alphaV/*genetics
Prefrontal Cortex/*metabolism
Vinculin/*genetics
Animals ; Apoptosis/genetics ; Connexin 43/metabolism ; Disease Models, Animal ; Gene Expression ; Immunohistochemistry ; Integrin alphaV/metabolism ; Male ; Neurons/metabolism ; Neurons/pathology ; Neurons/ultrastructure ; Prefrontal Cortex/pathology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Stress Disorders, Post-Traumatic/genetics ; Stress Disorders, Post-Traumatic/metabolism ; Stress Disorders, Post-Traumatic/pathology ; Vinculin/metabolism

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Skocz do pozycji: 18.

Tytuł:: Effects of mild induced hypothermia on hippocampal connexin 43 and glutamate transporter 1 expression following traumatic brain injury in rats.
Autorzy:: Li YH; Department of Obstetrics and Gynecology, Tangshan Gongren Hospital, Tangshan, Hebei 063000, P.R. China.
Zhang CL; Department of Cardiology, Tangshan Gongren Hospital, Tangshan, Hebei 063000, P.R. China.
Zhang XY; School of Basic Medical Sciences, Hebei United University, Tangshan, Hebei 063000, P.R. China.
Zhou HX; School of Basic Medical Sciences, Hebei United University, Tangshan, Hebei 063000, P.R. China.
Meng LL; School of Basic Medical Sciences, Hebei United University, Tangshan, Hebei 063000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2015 Mar; Vol. 11 (3), pp. 1991-6. Date of Electronic Publication: 2014 Nov 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hypothermia, Induced*
Brain Injuries/*metabolism
Connexin 43/*metabolism
Excitatory Amino Acid Transporter 2/*metabolism
Hippocampus/*metabolism
Animals ; Brain Edema/etiology ; Brain Edema/pathology ; Brain Edema/therapy ; Brain Injuries/pathology ; Brain Injuries/therapy ; Connexin 43/genetics ; Disease Models, Animal ; Excitatory Amino Acid Transporter 2/genetics ; Gene Expression ; Hippocampus/pathology ; Immunohistochemistry ; Male ; Maze Learning ; Memory ; Rats ; Up-Regulation

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Skocz do pozycji: 19.

Tytuł:: Artemisinin prevents electric remodeling following myocardial infarction possibly by upregulating the expression of connexin 43.
Autorzy:: Gu Y; Department of Cardiology, The Fourth Affiliated Hospital of Nantong University (The First People's Hospital of Yancheng), Yancheng, Jiangsu 224006, P.R. China.
Wu G; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China.
Wang X; Cardiovascular Research Institute of Wuhan University, Wuhan, Hubei 430060, P.R. China.
Wang X; Cardiovascular Research Institute of Wuhan University, Wuhan, Hubei 430060, P.R. China.
Wang Y; Department of Cardiology, The Fourth Affiliated Hospital of Nantong University (The First People's Hospital of Yancheng), Yancheng, Jiangsu 224006, P.R. China.
Huang C; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2014 Oct; Vol. 10 (4), pp. 1851-6. Date of Electronic Publication: 2014 Jul 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anti-Infective Agents/*pharmacology
Artemisinins/*pharmacology
Connexin 43/*metabolism
Ventricular Remodeling/*drug effects
Animals ; Connexin 43/genetics ; Electric Stimulation ; Male ; Myocardial Infarction/metabolism ; Myocardial Infarction/mortality ; Myocardial Infarction/pathology ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Survival Rate ; Tumor Necrosis Factor-alpha/metabolism ; Ventricular Fibrillation/physiopathology

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Skocz do pozycji: 20.

Tytuł:: Vorapaxar stabilizes permeability of the endothelial barrier under cholesterol stimulation via the AKT/JNK and NF‑κB signaling pathways.
Autorzy:: Pang J; Department of Vascular Surgery, Tiantai People's Hospital of Zhejiang Province, Taizhou, Zhejiang 317200, P.R. China.
Hu P; Department of Surgery, Tiantai People's Hospital of Zhejiang Province, Taizhou, Zhejiang 317200, P.R. China.
Wang J; Department of Internal Medicine, Tiantai People's Hospital of Zhejiang Province, Taizhou, Zhejiang 317200, P.R. China.
Jiang J; Department of Vascular Surgery, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. China.
Lai J; Department of Vascular Surgery, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2019 Jun; Vol. 19 (6), pp. 5291-5300. Date of Electronic Publication: 2019 Apr 30.
Typ publikacji:: Journal Article
MeSH Terms:: Lactones/*pharmacology
Pyridines/*pharmacology
Signal Transduction/*drug effects
Calcium/metabolism ; Cell Line ; Cell Survival/drug effects ; Cholesterol/pharmacology ; Connexin 43/metabolism ; Cytokines/genetics ; Cytokines/metabolism ; Endothelial Cells/cytology ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Glycogen Synthase Kinase 3 beta/metabolism ; Humans ; JNK Mitogen-Activated Protein Kinases/metabolism ; NF-kappa B/metabolism ; Nitric Oxide/metabolism ; Permeability/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Up-Regulation/drug effects

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