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Tytuł :
Aminocarboxylic acids related to aspergillomarasmine A (AMA) and ethylenediamine-N,N'-disuccinic acid (EDDS) are strong zinc-binders and inhibitors of the metallo-beta-lactamase NDM-1.
Autorzy :
Tehrani KHME; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands. .
Fu H; Department of Chemical and Pharmaceutical Biology, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands. .
Brüchle NC; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands. .
Mashayekhi V; Division of Cell Biology, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Prats Luján A; Department of Chemical and Pharmaceutical Biology, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands. .
van Haren MJ; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands. .
Poelarends GJ; Department of Chemical and Pharmaceutical Biology, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands. .
Martin NI; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands. .
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Mar 10; Vol. 56 (20), pp. 3047-3049.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem. Commun. (Camb.) Subsets: MEDLINE
MeSH Terms :
Aspartic Acid/*analogs & derivatives
Coordination Complexes/*pharmacology
Escherichia coli Proteins/*antagonists & inhibitors
Ethylenediamines/*pharmacology
Succinates/*pharmacology
Zinc/*pharmacology
beta-Lactamase Inhibitors/*pharmacology
Amino Acids/chemistry ; Amino Acids/pharmacology ; Aspartic Acid/chemistry ; Aspartic Acid/pharmacology ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Dose-Response Relationship, Drug ; Escherichia coli Proteins/metabolism ; Ethylenediamines/chemistry ; Molecular Structure ; Structure-Activity Relationship ; Succinates/chemistry ; Zinc/chemistry ; beta-Lactamase Inhibitors/chemical synthesis ; beta-Lactamase Inhibitors/chemistry ; beta-Lactamases/metabolism
Czasopismo naukowe
Tytuł :
Niacin-ligated platinum(iv)-ruthenium(ii) chimeric complexes synergistically suppress tumor metastasis and growth with potentially reduced toxicity in vivo.
Autorzy :
Shu L; The First Affiliated Hospital, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, School of Medicine, Zhejiang University, Hangzhou, 310003, P. R. China. , Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, P. R. China.
Ren L; Department of Medical Oncology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, P. R. China.
Wang Y; The First Affiliated Hospital, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, School of Medicine, Zhejiang University, Hangzhou, 310003, P. R. China. , Zhejiang, University, Hangzhou, P. R. China.
Fang T; Jinhua People's Hospital, Jinhua, Zhejiang Province 321000, P. R. China.
Ye Z; Jinhua People's Hospital, Jinhua, Zhejiang Province 321000, P. R. China.
Han W; Department of Medical Oncology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, P. R. China.
Chen C; College of Life Sciences, Huzhou University, Huzhou, 313000, P. R. China. .
Wang H; The First Affiliated Hospital, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, School of Medicine, Zhejiang University, Hangzhou, 310003, P. R. China. .
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Mar 10; Vol. 56 (20), pp. 3069-3072.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem. Commun. (Camb.) Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*pharmacology
Coordination Complexes/*pharmacology
Niacin/*pharmacology
Platinum/*pharmacology
Ruthenium/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Body Weight/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cisplatin/chemistry ; Cisplatin/pharmacology ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Female ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Inbred ICR ; Mice, Nude ; Molecular Structure ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/pathology ; Niacin/chemistry ; Platinum/chemistry ; Ruthenium/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
The First Anticancer Tris(pyrazolyl)borate Molybdenum(IV) Complexes: Tested in Vitro and in Vivo-A Comparison of O,O-, S,O-, and N,N-Chelate Effects.
Autorzy :
Berasaluce I; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.
Cseh K; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.
Roller A; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.
Hejl M; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.
Heffeter P; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.; Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, 1090, Vienna, Austria.
Berger W; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.; Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, 1090, Vienna, Austria.
Jakupec MA; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.
Kandioller W; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.
Malarek MS; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.
Keppler BK; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Feb 17; Vol. 26 (10), pp. 2211-2221. Date of Electronic Publication: 2019 Nov 19.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*chemistry
Borates/*chemistry
Coordination Complexes/*chemistry
Molybdenum/*chemistry
Pyrazoles/*chemistry
Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Cell Survival/drug effects ; Chelating Agents/chemistry ; Coordination Complexes/pharmacology ; Coordination Complexes/therapeutic use ; Crystallography, X-Ray ; Drug Screening Assays, Antitumor ; Drug Stability ; Humans ; Ligands ; Mice ; Mice, Inbred BALB C ; Molecular Conformation ; Neoplasms/drug therapy ; Nitrogen/chemistry ; Oxygen/chemistry ; Sulfur/chemistry
Czasopismo naukowe
Tytuł :
Gallium(iii)-polypyridyl complexes as anti-osteosarcoma stem cell agents.
Autorzy :
Robin P; School of Chemistry, University of Leicester, Leicester, LE1 7RH, UK. .
Singh K
Suntharalingam K
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Feb 04; Vol. 56 (10), pp. 1509-1512.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem. Commun. (Camb.) Subsets: MEDLINE
MeSH Terms :
Coordination Complexes/*pharmacology
Gallium/*chemistry
Neoplastic Stem Cells/*drug effects
Cell Line, Tumor ; Cell Nucleus/chemistry ; Cell Nucleus/metabolism ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Coordination Complexes/chemistry ; Coordination Complexes/metabolism ; Humans ; Neoplastic Stem Cells/cytology ; Neoplastic Stem Cells/metabolism ; Osteosarcoma/metabolism ; Osteosarcoma/pathology
Czasopismo naukowe
Tytuł :
Photoactive metal complexes that bind DNA and other biomolecules as cell probes, therapeutics, and theranostics.
Autorzy :
Saeed HK; Department of Chemistry, Brooklyn College, The City University of New York, Brooklyn, NY 11210, USA.
Sreedharan S; CRUK/MRC Oxford Institute for Radiation Oncology University of Oxford, Oxford, Oxfordshire OX3 7DQ, UK.
Thomas JA; Department of Chemistry, University of Sheffield, Sheffield S10 2TN, UK. .
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Feb 04; Vol. 56 (10), pp. 1464-1480. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article; Review
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem. Commun. (Camb.) Subsets: MEDLINE
MeSH Terms :
Coordination Complexes/*chemistry
DNA/*chemistry
Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Apoptosis/drug effects ; Bacteria/drug effects ; Contrast Media/chemistry ; Contrast Media/metabolism ; Coordination Complexes/metabolism ; Coordination Complexes/toxicity ; DNA/metabolism ; Humans ; Molecular Probes/chemistry ; Molecular Probes/metabolism ; Theranostic Nanomedicine
Czasopismo naukowe
Tytuł :
A palladium-catalyst stabilized in the chiral environment of a monoclonal antibody in water.
Autorzy :
Kobayashi Y; Department of Macromolecular Science, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan. .
Murata K; Department of Macromolecular Science, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan. .
Harada A; The Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki 567-0047, Japan. .
Yamaguchi H; Department of Macromolecular Science, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan. .
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Feb 04; Vol. 56 (10), pp. 1605-1607. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem. Commun. (Camb.) Subsets: MEDLINE
MeSH Terms :
Antibodies, Monoclonal/*chemistry
Coordination Complexes/*chemistry
Palladium/*chemistry
Allyl Compounds/chemical synthesis ; Allyl Compounds/chemistry ; Amination ; Animals ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/metabolism ; Benzylamines/chemical synthesis ; Benzylamines/chemistry ; Catalysis ; Cattle ; Coordination Complexes/immunology ; Coordination Complexes/metabolism ; Cross Reactions/immunology ; Female ; Gastropoda/chemistry ; Hemocyanins/chemistry ; Mice, Inbred BALB C ; Protein Binding ; Rhodium/chemistry ; Serum Albumin, Bovine/chemistry ; Stereoisomerism ; Water/chemistry
Czasopismo naukowe
Tytuł :
DFT Mechanistic Insight into the Dioxygenase-like Reactivity of a Co III -peroxo Complex: O-O Bond Cleavage via a [1,3]-Sigmatropic Rearrangement-like Mechanism.
Autorzy :
Zhao R; School of Chemical Sciences , University of Chinese Academy of Sciences , Jia #19, Yuquan Road , Beijing 100039 , China.
Guo J; School of Chemical Sciences , University of Chinese Academy of Sciences , Jia #19, Yuquan Road , Beijing 100039 , China.
Zhang C; School of Chemical Sciences , University of Chinese Academy of Sciences , Jia #19, Yuquan Road , Beijing 100039 , China.
Lu Y; School of Chemical Sciences , University of Chinese Academy of Sciences , Jia #19, Yuquan Road , Beijing 100039 , China.
Dagnaw WM; School of Chemical Sciences , University of Chinese Academy of Sciences , Jia #19, Yuquan Road , Beijing 100039 , China.
Wang ZX; School of Chemical Sciences , University of Chinese Academy of Sciences , Jia #19, Yuquan Road , Beijing 100039 , China.
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Źródło :
Inorganic chemistry [Inorg Chem] 2020 Feb 03; Vol. 59 (3), pp. 2051-2061. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article
Journal Info :
Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-510X (Electronic) Linking ISSN: 00201669 NLM ISO Abbreviation: Inorg Chem Subsets: MEDLINE
MeSH Terms :
Density Functional Theory*
Chelating Agents/*chemistry
Cobalt/*chemistry
Coordination Complexes/*chemistry
Dioxygenases/*chemistry
Peroxides/*chemistry
Chelating Agents/chemical synthesis ; Chelating Agents/metabolism ; Cobalt/metabolism ; Coordination Complexes/chemical synthesis ; Coordination Complexes/metabolism ; Dioxygenases/metabolism ; Models, Molecular ; Molecular Structure ; Oxygen/chemistry ; Oxygen/metabolism ; Peroxides/metabolism
Czasopismo naukowe
Tytuł :
[ nat/44 Sc(pypa)] - : Thermodynamic Stability, Radiolabeling, and Biodistribution of a Prostate-Specific-Membrane-Antigen-Targeting Conjugate.
Autorzy :
Li L; Life Sciences Division , TRIUMF , 4004 Wesbrook Mall , Vancouver , British Columbia V6T 2A3 , Canada.
Jaraquemada-Peláez MG
Aluicio-Sarduy E; Department of Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Wang X
Jiang D; Department of Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Sakheie M; Life Sciences Division , TRIUMF , 4004 Wesbrook Mall , Vancouver , British Columbia V6T 2A3 , Canada.
Kuo HT; Department of Molecular Oncology , BC Cancer , 675 West 10th Ave , Vancouver , British Columbia V5Z 1L3 , Canada.
Barnhart TE; Department of Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Cai W; Department of Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Radchenko V; Life Sciences Division , TRIUMF , 4004 Wesbrook Mall , Vancouver , British Columbia V6T 2A3 , Canada.
Schaffer P; Life Sciences Division , TRIUMF , 4004 Wesbrook Mall , Vancouver , British Columbia V6T 2A3 , Canada.
Lin KS; Department of Molecular Oncology , BC Cancer , 675 West 10th Ave , Vancouver , British Columbia V5Z 1L3 , Canada.
Engle JW; Department of Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Bénard F; Department of Molecular Oncology , BC Cancer , 675 West 10th Ave , Vancouver , British Columbia V5Z 1L3 , Canada.
Orvig C
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Źródło :
Inorganic chemistry [Inorg Chem] 2020 Feb 03; Vol. 59 (3), pp. 1985-1995. Date of Electronic Publication: 2020 Jan 24.
Typ publikacji :
Journal Article
Journal Info :
Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-510X (Electronic) Linking ISSN: 00201669 NLM ISO Abbreviation: Inorg Chem Subsets: MEDLINE
MeSH Terms :
Thermodynamics*
Chelating Agents/*chemistry
Coordination Complexes/*chemistry
Neoplasms, Experimental/*diagnostic imaging
Prostate-Specific Antigen/*analysis
Radioisotopes/*chemistry
Radiopharmaceuticals/*chemistry
Scandium/*chemistry
Animals ; Chelating Agents/chemical synthesis ; Chelating Agents/pharmacokinetics ; Coordination Complexes/chemical synthesis ; Coordination Complexes/pharmacokinetics ; Density Functional Theory ; Humans ; Hydrogen-Ion Concentration ; Mice ; Mice, Nude ; Models, Molecular ; Molecular Structure ; Positron-Emission Tomography ; Radioisotopes/pharmacokinetics ; Radiopharmaceuticals/chemical synthesis ; Radiopharmaceuticals/pharmacokinetics ; Scandium/pharmacokinetics ; Tissue Distribution
Czasopismo naukowe
Tytuł :
A Zr-cluster based thermostable, self-healing and adaptive metallogel with chromogenic properties responds to multiple stimuli with reversible radical interaction.
Autorzy :
Zhang YJ; College of Science, Hebei University of Science and Technology, Yuhua Road 70, Shijiazhuang 050080, P. R. China. .
Shen FJ
Li YJ
Pang XL
Zhang C
Ren JJ
Yu XD
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Feb 25; Vol. 56 (16), pp. 2439-2442.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem. Commun. (Camb.) Subsets: MEDLINE
MeSH Terms :
Temperature*
Coordination Complexes/*chemistry
Zirconium/*chemistry
Amines/chemistry ; Coordination Complexes/chemical synthesis ; Gels/chemical synthesis ; Gels/chemistry ; Molecular Structure ; Particle Size ; Surface Properties
Czasopismo naukowe
Tytuł :
Ratiometric detection of amyloid-β aggregation by a dual-emissive tris-heteroleptic ruthenium complex.
Autorzy :
Shao JY; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China. , CAS Key Laboratory of Photochemistry, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. .
Wu SH; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China. .
Ma J; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China. .
Gong ZL; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. .
Sun TG; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. .
Jin Y; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. .
Yang R; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China. .
Sun B; Institute of BioPharmaceutical Research, Liaocheng University, Liaocheng 252000, China.
Zhong YW; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. and School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Feb 18; Vol. 56 (14), pp. 2087-2090. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem. Commun. (Camb.) Subsets: MEDLINE
MeSH Terms :
Amyloid beta-Peptides/*analysis
Coordination Complexes/*chemistry
Ruthenium/*chemistry
Coordination Complexes/chemical synthesis ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Protein Aggregates
Czasopismo naukowe
Tytuł :
Can a Mononuclear Iron(III)-Superoxo Active Site Catalyze the Decarboxylation of Dodecanoic Acid in UndA to Produce Biofuels?
Autorzy :
Lin YT; The Manchester Institute of Biotechnology and Department of, Chemical Engineering and Analytical Science, The University of, Manchester, 131 Princess Street, Manchester, M1 7DN, UK.
Stańczak A; The Manchester Institute of Biotechnology and Department of, Chemical Engineering and Analytical Science, The University of, Manchester, 131 Princess Street, Manchester, M1 7DN, UK.; Faculty of Chemistry, Silesian University of Technology, ks. Marcina Strzody 9, 44-100, Gliwice, Poland.; Tunneling Group, Biotechnology Centre, Silesian University of Technology, ul. Krzywoustego 8, 44-100, Gliwice, Poland.
Manchev Y; The Manchester Institute of Biotechnology and Department of, Chemical Engineering and Analytical Science, The University of, Manchester, 131 Princess Street, Manchester, M1 7DN, UK.
Straganz GD; Graz University of Technology, Institute of Biochemistry, Petergasse 12, 8010, Graz, Austria.
de Visser SP; The Manchester Institute of Biotechnology and Department of, Chemical Engineering and Analytical Science, The University of, Manchester, 131 Princess Street, Manchester, M1 7DN, UK.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Feb 17; Vol. 26 (10), pp. 2233-2242. Date of Electronic Publication: 2019 Nov 26.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE
MeSH Terms :
Biofuels*
Carboxy-Lyases/*metabolism
Coordination Complexes/*chemistry
Ferric Compounds/*chemistry
Carboxy-Lyases/chemistry ; Catalytic Domain ; Coordination Complexes/metabolism ; Decarboxylation ; Density Functional Theory ; Hydrogen/chemistry ; Molecular Conformation ; Temperature ; Thermodynamics
Czasopismo naukowe
Tytuł :
Luminescent Pt II and Pt IV Platinacycles with Anticancer Activity Against Multiplatinum-Resistant Metastatic CRC and CRPC Cell Models.
Autorzy :
Lázaro A; Dpt de Química Inorgànica i Orgànica, Secció de Química Inorgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1-11, 08028, Barcelona, Spain.
Balcells C; Dpt. of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Av. Diagonal, 643, 08028, Barcelona, Spain.
Quirante J; Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain.; Institut de Biomedicina, Universitat de Barcelona (IBUB), 08028, Barcelona, Spain.
Badia J; Dpt de Bioquímica i Fisiologia, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain.; Institut de Biomedicina, Universitat de Barcelona (IBUB), 08028, Barcelona, Spain.
Baldomà L; Dpt de Bioquímica i Fisiologia, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain.; Institut de Biomedicina, Universitat de Barcelona (IBUB), 08028, Barcelona, Spain.
Ward JS; Dpt of Chemistry, Nanoscience Center, University of Jyvaskyla, P.O. Box 35, Jyvaskyla, 40014, Finland.
Rissanen K; Dpt of Chemistry, Nanoscience Center, University of Jyvaskyla, P.O. Box 35, Jyvaskyla, 40014, Finland.
Font-Bardia M; Unitat de difracció de RX, CCiTUB, Universitat de Barcelona, Solé i Sabarís 1-3, 08028, Barcelona, Spain.
Rodríguez L; Dpt de Química Inorgànica i Orgànica, Secció de Química Inorgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1-11, 08028, Barcelona, Spain.; Institut de Nanociència i Nanotecnologia, Universitat de, Barcelona (IN2UB), 08028, Barcelona, Spain.
Crespo M; Dpt de Química Inorgànica i Orgànica, Secció de Química Inorgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1-11, 08028, Barcelona, Spain.; Institut de Biomedicina, Universitat de Barcelona (IBUB), 08028, Barcelona, Spain.
Cascante M; Dpt. of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Av. Diagonal, 643, 08028, Barcelona, Spain.; Institut de Biomedicina, Universitat de Barcelona (IBUB), 08028, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticasydigestivas, (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Feb 11; Vol. 26 (9), pp. 1947-1952. Date of Electronic Publication: 2020 Jan 30.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE
MeSH Terms :
Drug Resistance, Neoplasm*/drug effects
Antineoplastic Agents/*pharmacology
Cell Proliferation/*drug effects
Coordination Complexes/*chemistry
Platinum/*chemistry
Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cisplatin/pharmacology ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Coordination Complexes/pharmacology ; Drug Screening Assays, Antitumor ; Humans ; Male ; Molecular Conformation ; Prostatic Neoplasms, Castration-Resistant/metabolism ; Prostatic Neoplasms, Castration-Resistant/pathology ; Spectrometry, Fluorescence
Czasopismo naukowe
Tytuł :
Predicting the Thermodynamic Stability of Zirconium Radiotracers.
Autorzy :
Holland JP; University of Zurich , Department of Chemistry , Winterthurerstrasse 190 , CH-8057 Zurich , Switzerland.
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Źródło :
Inorganic chemistry [Inorg Chem] 2020 Feb 03; Vol. 59 (3), pp. 2070-2082. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article
Journal Info :
Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-510X (Electronic) Linking ISSN: 00201669 NLM ISO Abbreviation: Inorg Chem Subsets: MEDLINE
MeSH Terms :
Thermodynamics*
Chelating Agents/*chemistry
Coordination Complexes/*chemistry
Deferoxamine/*chemistry
Zirconium/*chemistry
Chelating Agents/chemical synthesis ; Coordination Complexes/chemical synthesis ; Density Functional Theory ; Ligands ; Models, Molecular ; Positron-Emission Tomography ; Radioactive Tracers
Czasopismo naukowe
Tytuł :
Construction of an iridium(iii)-complex-loaded MOF nanoplatform mediated with a dual-responsive polycationic polymer for photodynamic therapy and cell imaging.
Autorzy :
Zhang Y; Tianjin Key Laboratory of Drug Targeting and Bioimaging, School of Chemistry and Chemical Engineering, Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, Tianjin University of Technology, Tianjin 300384, P. R. China. .
Fu H; Tianjin Key Laboratory of Drug Targeting and Bioimaging, School of Chemistry and Chemical Engineering, Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, Tianjin University of Technology, Tianjin 300384, P. R. China. .
Chen S; Tianjin Key Laboratory of Drug Targeting and Bioimaging, School of Chemistry and Chemical Engineering, Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, Tianjin University of Technology, Tianjin 300384, P. R. China. .
Liu B; Department of Chemistry and Biochemistry, North Dakota State University, Fargo, ND 58108-6050, USA.
Sun W; Department of Chemistry and Biochemistry, North Dakota State University, Fargo, ND 58108-6050, USA.
Gao H; Tianjin Key Laboratory of Drug Targeting and Bioimaging, School of Chemistry and Chemical Engineering, Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, Tianjin University of Technology, Tianjin 300384, P. R. China. .
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Jan 16; Vol. 56 (5), pp. 762-765. Date of Electronic Publication: 2019 Dec 17.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem. Commun. (Camb.) Subsets: MEDLINE
MeSH Terms :
Acrylic Resins/*pharmacology
Coordination Complexes/*pharmacology
Metal-Organic Frameworks/*pharmacology
Nanoparticles/*chemistry
Photosensitizing Agents/*pharmacology
Acrylic Resins/chemistry ; Acrylic Resins/toxicity ; Coordination Complexes/chemistry ; Coordination Complexes/toxicity ; Drug Design ; HeLa Cells ; Humans ; Iridium/chemistry ; Metal-Organic Frameworks/chemistry ; Metal-Organic Frameworks/toxicity ; Microscopy, Fluorescence/methods ; Photochemotherapy/methods ; Photosensitizing Agents/chemistry ; Photosensitizing Agents/toxicity ; Quaternary Ammonium Compounds/chemistry ; Quaternary Ammonium Compounds/pharmacology ; Quaternary Ammonium Compounds/toxicity ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Alkyl gallium(III) quinolinolates: A new class of highly selective anti-leishmanial agents.
Autorzy :
Duffin RN; School of Chemistry, Monash University, Clayton, Melbourne, VIC, 3800, Australia.
Blair VL; School of Chemistry, Monash University, Clayton, Melbourne, VIC, 3800, Australia.
Kedzierski L; Faculty of Veterinary and Agricultural Sciences at the Peter Doherty Institute for Infection and Immunity, 792 Elizabeth Street, Melbourne, 3000, Victoria, Australia.
Andrews PC; School of Chemistry, Monash University, Clayton, Melbourne, VIC, 3800, Australia. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2020 Jan 15; Vol. 186, pp. 111895. Date of Electronic Publication: 2019 Nov 18.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
MeSH Terms :
Antiprotozoal Agents/*pharmacology
Coordination Complexes/*pharmacology
Gallium/*pharmacology
Hydroxyquinolines/*pharmacology
Leishmania major/*drug effects
Animals ; Antiprotozoal Agents/chemical synthesis ; Antiprotozoal Agents/chemistry ; COS Cells ; Cell Survival/drug effects ; Cells, Cultured ; Chlorocebus aethiops ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Dose-Response Relationship, Drug ; Gallium/chemistry ; HeLa Cells ; Humans ; Hydroxyquinolines/chemistry ; Leishmania major/metabolism ; Mice ; Molecular Structure ; Parasitic Sensitivity Tests ; Reactive Oxygen Species/analysis ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Ruthenium(II) Conjugates of Boron-Dipyrromethene and Biotin for Targeted Photodynamic Therapy in Red Light.
Autorzy :
Paul S
Kundu P
Bhattacharyya U
Garai A
Maji RC
Kondaiah P
Chakravarty AR
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Źródło :
Inorganic chemistry [Inorg Chem] 2020 Jan 06; Vol. 59 (1), pp. 913-924. Date of Electronic Publication: 2019 Dec 11.
Typ publikacji :
Journal Article
Journal Info :
Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-510X (Electronic) Linking ISSN: 00201669 NLM ISO Abbreviation: Inorg Chem Subsets: MEDLINE
MeSH Terms :
Light*
Photochemotherapy*
Antineoplastic Agents/*pharmacology
Coordination Complexes/*pharmacology
Photosensitizing Agents/*pharmacology
A549 Cells ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Biotin/chemistry ; Biotin/pharmacology ; Boron/chemistry ; Boron/pharmacology ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; DNA Cleavage/drug effects ; Density Functional Theory ; Drug Screening Assays, Antitumor ; Humans ; Models, Molecular ; Optical Imaging ; Photosensitizing Agents/chemical synthesis ; Photosensitizing Agents/chemistry ; Porphobilinogen/analogs & derivatives ; Porphobilinogen/chemistry ; Porphobilinogen/pharmacology ; Ruthenium/chemistry ; Ruthenium/pharmacology
Czasopismo naukowe
Tytuł :
The Fluorine Effect in Zwitterionic Half-Sandwich Iridium(III) Anticancer Complexes.
Autorzy :
Yang Y; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering , Qufu Normal University , Qufu 273165 , People's Republic of China.
Guo L; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering , Qufu Normal University , Qufu 273165 , People's Republic of China.
Ge X; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering , Qufu Normal University , Qufu 273165 , People's Republic of China.
Zhu T; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering , Qufu Normal University , Qufu 273165 , People's Republic of China.
Chen W; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering , Qufu Normal University , Qufu 273165 , People's Republic of China.
Zhou H; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering , Qufu Normal University , Qufu 273165 , People's Republic of China.
Zhao L; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering , Qufu Normal University , Qufu 273165 , People's Republic of China.
Liu Z; Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering , Qufu Normal University , Qufu 273165 , People's Republic of China.
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Źródło :
Inorganic chemistry [Inorg Chem] 2020 Jan 06; Vol. 59 (1), pp. 748-758. Date of Electronic Publication: 2019 Dec 06.
Typ publikacji :
Journal Article
Journal Info :
Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-510X (Electronic) Linking ISSN: 00201669 NLM ISO Abbreviation: Inorg Chem Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*pharmacology
Coordination Complexes/*pharmacology
Fluorine/*chemistry
Iridium/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cisplatin/chemistry ; Cisplatin/pharmacology ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Crystallography, X-Ray ; Drug Screening Assays, Antitumor ; Humans ; Iridium/chemistry ; Models, Molecular ; Molecular Structure ; Reactive Oxygen Species/analysis
Czasopismo naukowe
Tytuł :
Synthesis, Anticancer Evaluation and Synergistic Effects with cisplatin of Novel Palladium Complexes: DNA, BSA Interactions and Molecular Docking Study.
Autorzy :
Joksimović N; Faculty of Science, Department of Chemistry, University of Kragujevac, Radoja Domanovića 12, 34000 Kragujevac, Serbia.
Janković N; Faculty of Science, Department of Chemistry, University of Kragujevac, Radoja Domanovića 12, 34000 Kragujevac, Serbia.
Petronijević J; Faculty of Science, Department of Chemistry, University of Kragujevac, Radoja Domanovića 12, 34000 Kragujevac, Serbia.
Baskić D; Faculty of Medical Sciences, Centre for Molecular Medicine and Stem Cell Research, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Popovic S; Faculty of Medical Sciences, Centre for Molecular Medicine and Stem Cell Research, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Todorović D; Faculty of Medical Sciences, Centre for Molecular Medicine and Stem Cell Research, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Zarić M; Faculty of Medical Sciences, Centre for Molecular Medicine and Stem Cell Research, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Klisurić O; Faculty of Sciences, Department of Physics, University of Novi Sad, Trg Dositeja Obradovića 4, 21000 Novi Sad, Serbia.
Vraneš M; Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia.
Tot A; Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia.
Bugarčić Z; Faculty of Science, Department of Chemistry, University of Kragujevac, Radoja Domanovića 12, 34000 Kragujevac, Serbia.
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Źródło :
Medicinal chemistry (Shariqah (United Arab Emirates)) [Med Chem] 2020; Vol. 16 (1), pp. 78-92.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101240303 Publication Model: Print Cited Medium: Internet ISSN: 1875-6638 (Electronic) Linking ISSN: 15734064 NLM ISO Abbreviation: Med Chem Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*pharmacology
Coordination Complexes/*pharmacology
DNA/*chemistry
Palladium/*pharmacology
Serum Albumin, Bovine/*chemistry
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cattle ; Cell Line ; Cell Proliferation/drug effects ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Fibroblasts/drug effects ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Palladium/chemistry ; Structure-Activity Relationship ; Viscosity
Czasopismo naukowe
Tytuł :
Synthesis, Characterization, and Biological Properties of Steroidal Ruthenium(II) and Iridium(III) Complexes Based on the Androst-16-en-3-ol Framework.
Autorzy :
Koch V; Institute of Organic Chemistry (IOC) , Karlsruhe Institute of Technology (KIT) , Fritz-Haber-Weg 6 , 76131 Karlsruhe , Germany.
Meschkov A; Institute of Organic Chemistry (IOC) , Karlsruhe Institute of Technology (KIT) , Fritz-Haber-Weg 6 , 76131 Karlsruhe , Germany.; Institute of Functional Interfaces (IFG) , Karlsruhe Institute of Technology (KIT) , Hermann von Helmholtz Platz 1 , 76344 Eggenstein-Leopoldshafen , Germany.
Feuerstein W; Institute of Inorganic Chemistry, Division Molecular Chemistry , Karlsruhe Institute of Technology (KIT) , Engesserstr. 15 , 76131 Karlsruhe , Germany.
Pfeifer J; Institute of Functional Interfaces (IFG) , Karlsruhe Institute of Technology (KIT) , Hermann von Helmholtz Platz 1 , 76344 Eggenstein-Leopoldshafen , Germany.
Fuhr O; Institute for Nanotechnology (INT) and Karlsruhe Nano Micro Facility (KNMF) , Karlsruhe Institute of Technology (KIT) , Hermann von Helmholtz Platz 1 , 76344 Eggenstein-Leopoldshafen , Germany.
Nieger M; Department of Chemistry , University of Helsinki , P.O. Box 55 , 00014 Helsinki , Finland.
Schepers U; Institute of Organic Chemistry (IOC) , Karlsruhe Institute of Technology (KIT) , Fritz-Haber-Weg 6 , 76131 Karlsruhe , Germany.; Institute of Functional Interfaces (IFG) , Karlsruhe Institute of Technology (KIT) , Hermann von Helmholtz Platz 1 , 76344 Eggenstein-Leopoldshafen , Germany.
Bräse S; Institute of Organic Chemistry (IOC) , Karlsruhe Institute of Technology (KIT) , Fritz-Haber-Weg 6 , 76131 Karlsruhe , Germany.; Institute of Toxicology and Genetics , Karlsruhe Institute of Technology (KIT) , Hermann-von-Helmholtz-Platz 1 , D-76344 Eggenstein-Leopoldshafen , Germany.
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Źródło :
Inorganic chemistry [Inorg Chem] 2019 Dec 02; Vol. 58 (23), pp. 15917-15926. Date of Electronic Publication: 2019 Nov 12.
Typ publikacji :
Journal Article
Journal Info :
Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-510X (Electronic) Linking ISSN: 00201669 NLM ISO Abbreviation: Inorg Chem Subsets: MEDLINE
MeSH Terms :
Androstenols/*pharmacology
Antineoplastic Agents/*pharmacology
Coordination Complexes/*pharmacology
Iridium/*pharmacology
Ruthenium/*pharmacology
Androstenols/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Iridium/chemistry ; Ligands ; Models, Molecular ; Molecular Structure ; Ruthenium/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Ni(II), Pd(II), and Pt(II) Complexes of the Hedgehog Pathway Inhibitor GANT61-D.
Autorzy :
Ryan AL; Department of Chemistry , Royal College of Surgeons in Ireland , 123 St. Stephen's Green , Dublin D02 YN77 , Ireland.
Fitzgerald MC; Department of Physiology and Medical Physics , Royal College of Surgeons in Ireland , 31A York Street , Dublin D02 YN77 , Ireland.; National Children's Research Centre at the Children's Health Ireland at Crumlin , Dublin D12 N512 , Ireland.
Ozsváth A; Department of Inorganic and Analytical Chemistry , University of Debrecen , Egyetem tér 1 , Debrecen H-4032 , Hungary.
Twamley B; School of Chemistry, Trinity College Dublin , University of Dublin , Dublin D02 PN40 , Ireland.
Buglyó P; Department of Inorganic and Analytical Chemistry , University of Debrecen , Egyetem tér 1 , Debrecen H-4032 , Hungary.
Murphy BM; Department of Physiology and Medical Physics , Royal College of Surgeons in Ireland , 31A York Street , Dublin D02 YN77 , Ireland.; National Children's Research Centre at the Children's Health Ireland at Crumlin , Dublin D12 N512 , Ireland.
Griffith DM; Department of Chemistry , Royal College of Surgeons in Ireland , 123 St. Stephen's Green , Dublin D02 YN77 , Ireland.
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Źródło :
Inorganic chemistry [Inorg Chem] 2019 Dec 02; Vol. 58 (23), pp. 16075-16086. Date of Electronic Publication: 2019 Nov 15.
Typ publikacji :
Journal Article
Journal Info :
Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-510X (Electronic) Linking ISSN: 00201669 NLM ISO Abbreviation: Inorg Chem Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*pharmacology
Coordination Complexes/*pharmacology
Nickel/*pharmacology
Palladium/*pharmacology
Platinum/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Crystallography, X-Ray ; Drug Screening Assays, Antitumor ; Humans ; Models, Molecular ; Molecular Structure ; Nickel/chemistry ; Palladium/chemistry ; Platinum/chemistry
Czasopismo naukowe

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