Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Coordination Complexes"" wg kryterium: Temat


Tytuł :
Coordination Complexes to Combat Bacterial Infections: Recent Developments, Current Directions and Future Opportunities.
Autorzy :
Pandey A; Department of Chemistry, Stony Brook University, 100 Nicolls Road, Stony Brook, NY, 11794, USA.
Boros E; Department of Chemistry, Stony Brook University, 100 Nicolls Road, Stony Brook, NY, 11794, USA.
Pokaż więcej
Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 May 06; Vol. 27 (26), pp. 7340-7350. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Bacterial Infections*/drug therapy
Coordination Complexes*/pharmacology
Coordination Complexes*/therapeutic use
Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Bacteria ; Humans ; Metals
Czasopismo naukowe
Tytuł :
Ruthenium complexes show promise when submitted to toxicological safety tests using alternative methodologies.
Autorzy :
Teixeira TM; Instituto de Ciências Biológicas, Universidade Federal de Goiás (UFG), CEP 74045-155, Goiânia, GO, Brazil; Aquatic Ecology and Toxicology, Center for Organismal Studies, University of Heidelberg, D-69117, Heidelberg, Germany. Electronic address: .
Arraes IG; Instituto de Ciências Biológicas, Universidade Federal de Goiás (UFG), CEP 74045-155, Goiânia, GO, Brazil.
Abreu DC; Instituto de Ciências Biológicas, Universidade Federal de Goiás (UFG), CEP 74045-155, Goiânia, GO, Brazil.
Oliveira KM; Departamento de Química, Universidade Federal de São Carlos (UFSCar), CP 676, CEP 13565-905, São Carlos, SP, Brazil; Departamento de Química, ICEB, Universidade Federal de Ouro Preto (UFOP), CEP 35400-000, Ouro Preto, MG, Brazil.
Correa RS; Departamento de Química, ICEB, Universidade Federal de Ouro Preto (UFOP), CEP 35400-000, Ouro Preto, MG, Brazil.
Batista AA; Departamento de Química, Universidade Federal de São Carlos (UFSCar), CP 676, CEP 13565-905, São Carlos, SP, Brazil.
Braunbeck T; Aquatic Ecology and Toxicology, Center for Organismal Studies, University of Heidelberg, D-69117, Heidelberg, Germany.
de Paula Silveira Lacerda E; Instituto de Ciências Biológicas, Universidade Federal de Goiás (UFG), CEP 74045-155, Goiânia, GO, Brazil. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Apr 15; Vol. 216, pp. 113262. Date of Electronic Publication: 2021 Feb 15.
Typ publikacji :
Journal Article
MeSH Terms :
Coordination Complexes/*chemistry
Ruthenium/*chemistry
Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/metabolism ; Antineoplastic Agents/pharmacology ; Cattle ; Cell Line, Tumor ; Cell Survival/drug effects ; Coordination Complexes/metabolism ; Coordination Complexes/pharmacology ; Crystallography, X-Ray ; DNA/chemistry ; DNA/metabolism ; Embryo, Nonmammalian/drug effects ; Embryo, Nonmammalian/metabolism ; Humans ; Molecular Conformation ; Protein Binding ; Serum Albumin, Bovine/chemistry ; Serum Albumin, Bovine/metabolism ; Thermodynamics ; Zebrafish/growth & development
Czasopismo naukowe
Tytuł :
Development of photoactivable phenanthroline-based manganese(I) CO-Releasing molecules (PhotoCORMs) active against ESKAPE bacteria and bacterial biofilms.
Autorzy :
Toscani A; School of Cancer and Pharmaceutical Sciences, King's College London, London SE1 1DB, United Kingdom.
Hind C; Research and Development Institute, National Infections Service, Porton Down, Public Health England, Salisbury SP4 0JG, Wiltshire, United Kingdom.
Clifford M; Research and Development Institute, National Infections Service, Porton Down, Public Health England, Salisbury SP4 0JG, Wiltshire, United Kingdom.
Kim SH; School of Cancer and Pharmaceutical Sciences, King's College London, London SE1 1DB, United Kingdom.
Gucic A; School of Cancer and Pharmaceutical Sciences, King's College London, London SE1 1DB, United Kingdom.
Woolley C; Research and Development Institute, National Infections Service, Porton Down, Public Health England, Salisbury SP4 0JG, Wiltshire, United Kingdom.
Saeed N; School of Cancer and Pharmaceutical Sciences, King's College London, London SE1 1DB, United Kingdom.
Rahman KM; School of Cancer and Pharmaceutical Sciences, King's College London, London SE1 1DB, United Kingdom.
Sutton JM; Research and Development Institute, National Infections Service, Porton Down, Public Health England, Salisbury SP4 0JG, Wiltshire, United Kingdom. Electronic address: .
Castagnolo D; School of Cancer and Pharmaceutical Sciences, King's College London, London SE1 1DB, United Kingdom. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Mar 05; Vol. 213, pp. 113172. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Development*
Acinetobacter baumannii/*drug effects
Anti-Bacterial Agents/*pharmacology
Biofilms/*drug effects
Coordination Complexes/*pharmacology
Klebsiella pneumoniae/*drug effects
Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Carbon Monoxide/chemistry ; Carbon Monoxide/pharmacology ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Dose-Response Relationship, Drug ; Manganese/chemistry ; Manganese/pharmacology ; Microbial Sensitivity Tests ; Molecular Structure ; Phenanthrolines/chemistry ; Phenanthrolines/pharmacology ; Photochemical Processes ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Ruthenium compounds as potential therapeutic agents for type 2 diabetes mellitus.
Autorzy :
Maikoo S; School of Chemistry and Physics, University of KwaZulu-Natal, Pietermaritzburg, South Africa.
Makayane D; School of Chemistry and Physics, University of KwaZulu-Natal, Pietermaritzburg, South Africa.
Booysen IN; School of Chemistry and Physics, University of KwaZulu-Natal, Pietermaritzburg, South Africa. Electronic address: .
Ngubane P; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Khathi A; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Mar 05; Vol. 213, pp. 113064. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Coordination Complexes/*chemistry
Diabetes Mellitus, Type 2/*drug therapy
Enzyme Inhibitors/*chemistry
Glycogen Synthase Kinase 3/*antagonists & inhibitors
Hypoglycemic Agents/*chemistry
Protein Tyrosine Phosphatases/*antagonists & inhibitors
Ruthenium Compounds/*chemistry
Administration, Oral ; Animals ; Biocompatible Materials/chemistry ; Coordination Complexes/administration & dosage ; Coordination Complexes/pharmacokinetics ; Drug Carriers/chemistry ; Drug Liberation ; Enzyme Inhibitors/administration & dosage ; Enzyme Inhibitors/pharmacokinetics ; Humans ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/pharmacokinetics ; Islet Amyloid Polypeptide/metabolism ; Nanostructures/chemistry ; Polymers/chemistry ; Prodrugs/chemistry ; Prodrugs/pharmacology ; Protein Aggregates ; Structure-Activity Relationship ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Synthesis, DNA binding, antibacterial and anticancer properties of two novel water-soluble copper(II) complexes containing gluconate.
Autorzy :
Cai DH; Department of Applied Chemistry, South China Agricultural University, Guangzhou, 510642, PR China.
Zhang CL; Department of Applied Chemistry, South China Agricultural University, Guangzhou, 510642, PR China.
Liu QY; Department of Applied Chemistry, South China Agricultural University, Guangzhou, 510642, PR China.
He L; Department of Applied Chemistry, South China Agricultural University, Guangzhou, 510642, PR China. Electronic address: .
Liu YJ; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, PR China. Electronic address: .
Xiong YH; Department of Applied Chemistry, South China Agricultural University, Guangzhou, 510642, PR China.
Le XY; Department of Applied Chemistry, South China Agricultural University, Guangzhou, 510642, PR China. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Mar 05; Vol. 213, pp. 113182. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antineoplastic Agents/*pharmacology
Coordination Complexes/*pharmacology
Copper/*pharmacology
DNA/*drug effects
Gluconates/*pharmacology
Animals ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Bacillus subtilis/drug effects ; Binding Sites/drug effects ; Cattle ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Copper/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Escherichia coli/drug effects ; Gluconates/chemistry ; Humans ; Listeria monocytogenes/drug effects ; Models, Molecular ; Molecular Structure ; Solubility ; Staphylococcus aureus/drug effects ; Structure-Activity Relationship ; Tumor Cells, Cultured ; Water/chemistry
Czasopismo naukowe
Tytuł :
In situ remediation of 2,4-dicholrophenoxyacetic acid herbicide using amine-functionalized imidazole coordination complexes.
Autorzy :
Mansab S; Department of Environmental Sciences, Fatima Jinnah Women University, The Mall, Rawalpindi, Pakistan. .
Rafique U; Department of Environmental Sciences, Fatima Jinnah Women University, The Mall, Rawalpindi, Pakistan.
Pokaż więcej
Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Mar; Vol. 28 (12), pp. 15099-15113. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Journal Article
MeSH Terms :
Coordination Complexes*
Herbicides*
Water Pollutants, Chemical*/analysis
Adsorption ; Amines ; Asia ; Humans ; Imidazoles ; Kinetics ; Thermodynamics
Czasopismo naukowe
Tytuł :
Tunable Anticancer Activity of Furoylthiourea-Based Ru -Arene Complexes and Their Mechanism of Action.
Autorzy :
Swaminathan S; Department of Chemistry, National Institute of Technology, Tiruchirappalli, 620015, Tamil Nadu, India.
Haribabu J; Department of Chemistry, National Institute of Technology, Tiruchirappalli, 620015, Tamil Nadu, India.
Kalagatur NK; DRDO-BU Centre for Life Sciences, Bharathiar University Campus, Coimbatore, 641046, Tamil Nadu, India.
Nikhil M; Centre for Condensed Matter Theory, Department of Physics, Indian Institute of Science, Bangalore, 560012, Karnataka, India.
Balakrishnan N; Department of Chemistry, National Institute of Technology, Tiruchirappalli, 620015, Tamil Nadu, India.
Bhuvanesh NSP; Department of Chemistry, Texas A & M University, College station, Texas, 77842, USA.
Kadirvelu K; DRDO-BU Centre for Life Sciences, Bharathiar University Campus, Coimbatore, 641046, Tamil Nadu, India.
Kolandaivel P; Periyar University, Salem, 636011, Tamil Nadu, India.
Karvembu R; Department of Chemistry, National Institute of Technology, Tiruchirappalli, 620015, Tamil Nadu, India.
Pokaż więcej
Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 May 06; Vol. 27 (26), pp. 7418-7433. Date of Electronic Publication: 2021 Mar 12.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*/pharmacology
Coordination Complexes*/toxicity
Ruthenium*
Cell Line, Tumor ; Structure-Activity Relationship ; Vascular Endothelial Growth Factor A
Czasopismo naukowe
Tytuł :
Re Tricarbonyl Complexes as Coordinate Covalent Inhibitors for the SARS-CoV-2 Main Cysteine Protease.
Autorzy :
Karges J; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, 92093, USA.
Kalaj M; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, 92093, USA.
Gembicky M; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, 92093, USA.
Cohen SM; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, 92093, USA.
Pokaż więcej
Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 May 03; Vol. 60 (19), pp. 10716-10723. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
COVID-19/*drug therapy
Coordination Complexes/*pharmacology
Coronavirus 3C Proteases/*antagonists & inhibitors
Protease Inhibitors/*pharmacology
Rhenium/*pharmacology
SARS-CoV-2/*enzymology
Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Coordination Complexes/chemistry ; Coronavirus 3C Proteases/metabolism ; Drug Discovery ; Humans ; Models, Molecular ; Protease Inhibitors/chemistry ; Rhenium/chemistry ; SARS-CoV-2/drug effects
Czasopismo naukowe
Tytuł :
Recent advances in biological activities of rhodium complexes: Their applications in drug discovery research.
Autorzy :
Sohrabi M; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Saeedi M; Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Larijani B; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mahdavi M; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Apr 15; Vol. 216, pp. 113308. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Discovery*
Coordination Complexes/*chemistry
Rhodium/*chemistry
Coordination Complexes/metabolism ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/metabolism ; Humans ; Isomerases/antagonists & inhibitors ; Isomerases/metabolism ; Oxidoreductases/antagonists & inhibitors ; Oxidoreductases/metabolism ; Protein Kinases/chemistry ; Protein Kinases/metabolism ; STAT3 Transcription Factor/antagonists & inhibitors ; STAT3 Transcription Factor/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Dipyrrinato-Iridium(III) Complexes for Application in Photodynamic Therapy and Antimicrobial Photodynamic Inactivation.
Autorzy :
Hohlfeld BF; Institut für Chemie u. Biochemie, Freie Universität Berlin, Takustr. 3, 14195, Berlin, Germany.; biolitec research GmbH, Otto-Schott-Str. 15, 07745, Jena, Germany.
Gitter B; biolitec research GmbH, Otto-Schott-Str. 15, 07745, Jena, Germany.
Kingsbury CJ; Medicinal Chemistry, Trinity Translational Medicine Institute, Trinity Centre for Health Sciences, Trinity College Dublin, The University of Dublin, St James's Hospital, Dublin, 8, Ireland.
Flanagan KJ; Medicinal Chemistry, Trinity Translational Medicine Institute, Trinity Centre for Health Sciences, Trinity College Dublin, The University of Dublin, St James's Hospital, Dublin, 8, Ireland.
Steen D; biolitec research GmbH, Otto-Schott-Str. 15, 07745, Jena, Germany.
Wieland GD; biolitec research GmbH, Otto-Schott-Str. 15, 07745, Jena, Germany.
Kulak N; Institut für Chemie u. Biochemie, Freie Universität Berlin, Takustr. 3, 14195, Berlin, Germany.; Institut für Chemie, Otto-von-Guericke-Universität Magdeburg, Universitätsplatz 2, 39106, Magdeburg, Germany.
Senge MO; Medicinal Chemistry, Trinity Translational Medicine Institute, Trinity Centre for Health Sciences, Trinity College Dublin, The University of Dublin, St James's Hospital, Dublin, 8, Ireland.; Institute for Advanced Study (TUM-IAS), Technical University of Munich, Lichtenbergstrasse 2a, 85748, Garching, Germany.
Wiehe A; Institut für Chemie u. Biochemie, Freie Universität Berlin, Takustr. 3, 14195, Berlin, Germany.; biolitec research GmbH, Otto-Schott-Str. 15, 07745, Jena, Germany.
Pokaż więcej
Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Apr 12; Vol. 27 (21), pp. 6440-6459. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents*
Coordination Complexes*/pharmacology
Photochemotherapy*
Iridium ; Photosensitizing Agents
Czasopismo naukowe
Tytuł :
Cortisol-Producing Adrenal Adenomas With Intense Activity on 68Ga-Pentixafor PET/CT.
Autorzy :
Ding J; From the Department of Nuclear Medicine and Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine.
Tong A; Department of Endocrinology and Key Laboratory of Endocrinology, Ministry of Health, and Departments of.
Zhang Y; Urology.
Zhang H; Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Huo L; From the Department of Nuclear Medicine and Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine.
Pokaż więcej
Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2021 Apr 01; Vol. 46 (4), pp. 350-352.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Coordination Complexes*
Peptides, Cyclic*
Positron Emission Tomography Computed Tomography*
Adrenal Cortex Neoplasms/*diagnostic imaging
Adrenal Cortex Neoplasms/*metabolism
Adrenocortical Adenoma/*diagnostic imaging
Adrenocortical Adenoma/*metabolism
Female ; Humans ; Middle Aged
Czasopismo naukowe
Tytuł :
Influence of Complexation of Thiosemicarbazone Derivatives with Cu (II) Ions on Their Antitumor Activity against Melanoma Cells.
Autorzy :
Pitucha M; Independent Radiopharmacy Unit, Faculty of Pharmacy, Medical University of Lublin, PL-20093 Lublin, Poland.
Korga-Plewko A; Independent Medical Biology Unit, Faculty of Pharmacy, Medical University of Lublin, PL-20093 Lublin, Poland.
Czylkowska A; Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.
Rogalewicz B; Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.
Drozd M; Independent Radiopharmacy Unit, Faculty of Pharmacy, Medical University of Lublin, PL-20093 Lublin, Poland.
Iwan M; Chair and Department of Toxicology, Faculty of Pharmacy, Medical University of Lublin, PL-20093 Lublin, Poland.
Kubik J; Independent Medical Biology Unit, Faculty of Pharmacy, Medical University of Lublin, PL-20093 Lublin, Poland.
Humeniuk E; Independent Medical Biology Unit, Faculty of Pharmacy, Medical University of Lublin, PL-20093 Lublin, Poland.
Adamczuk G; Independent Medical Biology Unit, Faculty of Pharmacy, Medical University of Lublin, PL-20093 Lublin, Poland.
Karczmarzyk Z; Faculty of Science, Siedlce University of Natural Sciences and Humanities, 3 Maja 54, 08-110 Siedlce, Poland.
Fornal E; Chair and Department of Pathophysiology, Faculty of Medicine, Medical University of Lublin, PL-20090 Lublin, Poland.
Wysocki W; Faculty of Science, Siedlce University of Natural Sciences and Humanities, 3 Maja 54, 08-110 Siedlce, Poland.
Bartnik P; Faculty of Science, Siedlce University of Natural Sciences and Humanities, 3 Maja 54, 08-110 Siedlce, Poland.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 18; Vol. 22 (6). Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Coordination Complexes/*pharmacology
Copper/*pharmacology
Melanoma/*pathology
Thiosemicarbazones/*pharmacology
Apoptosis/drug effects ; Cell Line, Tumor ; Cell Shape/drug effects ; Cell Survival/drug effects ; Coordination Complexes/chemistry ; Copper/chemistry ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Hydrogen Bonding ; Inhibitory Concentration 50 ; Ions ; Melanoma/genetics ; Molecular Conformation ; Necrosis ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Temperature ; Thiosemicarbazones/chemistry
Czasopismo naukowe
Tytuł :
Transition Metal-Promoted Reactions in Aqueous Media and Biological Settings.
Autorzy :
Destito P; Centro Singular de Investigación en Química Biolóxica e Materiais, Moleculares (CIQUS) and Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.
Vidal C; Centro Singular de Investigación en Química Biolóxica e Materiais, Moleculares (CIQUS) and Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.
López F; Centro Singular de Investigación en Química Biolóxica e Materiais, Moleculares (CIQUS) and Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.; Instituto de Química Orgánica General (CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
Mascareñas JL; Centro Singular de Investigación en Química Biolóxica e Materiais, Moleculares (CIQUS) and Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.
Pokaż więcej
Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Mar 12; Vol. 27 (15), pp. 4789-4816. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Coordination Complexes*
Transition Elements*
Animals ; Catalysis ; Metals ; Mice
Czasopismo naukowe
Tytuł :
Guided Antitumoural Drugs: (Imidazol-2-ylidene)(L)gold(I) Complexes Seeking Cellular Targets Controlled by the Nature of Ligand L.
Autorzy :
Bär SI; Organic Chemistry Laboratory, University Bayreuth, Universitaetsstr. 30, 95447, Bayreuth, Germany.
Gold M; Organic Chemistry Laboratory, University Bayreuth, Universitaetsstr. 30, 95447, Bayreuth, Germany.
Schleser SW; Organic Chemistry Laboratory, University Bayreuth, Universitaetsstr. 30, 95447, Bayreuth, Germany.
Rehm T; Organic Chemistry Laboratory, University Bayreuth, Universitaetsstr. 30, 95447, Bayreuth, Germany.
Bär A; Organic Chemistry Laboratory, University Bayreuth, Universitaetsstr. 30, 95447, Bayreuth, Germany.
Köhler L; Organic Chemistry Laboratory, University Bayreuth, Universitaetsstr. 30, 95447, Bayreuth, Germany.
Carnell LR; Organic Chemistry Laboratory, University Bayreuth, Universitaetsstr. 30, 95447, Bayreuth, Germany.
Biersack B; Organic Chemistry Laboratory, University Bayreuth, Universitaetsstr. 30, 95447, Bayreuth, Germany.
Schobert R; Organic Chemistry Laboratory, University Bayreuth, Universitaetsstr. 30, 95447, Bayreuth, Germany.
Pokaż więcej
Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Mar 12; Vol. 27 (15), pp. 5003-5010. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*/pharmacology
Coordination Complexes*/toxicity
Pharmaceutical Preparations*
Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Gold ; Ligands
Czasopismo naukowe
Tytuł :
[Study on the Antioxidant Activity of Aloe-Emodin Metal Complex].
Autorzy :
Liu MY; Key Laboratory of the Ministry of Education for the Standardization of Traditional Chinese Medicine, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Pan XL; Key Laboratory of the Ministry of Education for the Standardization of Traditional Chinese Medicine, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Li XB; Key Laboratory of the Ministry of Education for the Standardization of Traditional Chinese Medicine, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Wu B; Key Laboratory of the Ministry of Education for the Standardization of Traditional Chinese Medicine, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Pokaż więcej
Źródło :
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition [Sichuan Da Xue Xue Bao Yi Xue Ban] 2021 Mar; Vol. 52 (2), pp. 241-247.
Typ publikacji :
Journal Article
MeSH Terms :
Aloe*
Coordination Complexes*
Emodin*
Anthraquinones ; Antioxidants
Czasopismo naukowe
Tytuł :
A photoactivatable Ru (II) complex bearing 2,9-diphenyl-1,10-phenanthroline: A potent chemotherapeutic drug inducing apoptosis in triple negative human breast adenocarcinoma cells.
Autorzy :
Mansour N; Faculty of Health and Medical Sciences, Department of Microbial and Cellular Sciences, University of Surrey, UK; Department of Natural Sciences, Lebanese American University, Chouran, Beirut, 1102-2801, Lebanon.
Bodman-Smith K; Faculty of Health and Medical Sciences, Department of Microbial and Cellular Sciences, University of Surrey, UK.
Khnayzer RS; Department of Natural Sciences, Lebanese American University, Chouran, Beirut, 1102-2801, Lebanon.
Daher CF; Department of Natural Sciences, Lebanese American University, Chouran, Beirut, 1102-2801, Lebanon. Electronic address: .
Pokaż więcej
Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Feb 25; Vol. 336, pp. 109317. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*drug therapy
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Coordination Complexes/*pharmacology
Phenanthrolines/*pharmacology
Ruthenium/*pharmacology
Triple Negative Breast Neoplasms/*drug therapy
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Drug Screening Assays, Antitumor ; Humans ; Phenanthrolines/chemistry ; Photochemical Processes ; Ruthenium/chemistry ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Quinoline Functionalized Schiff Base Silver (I) Complexes: Interactions with Biomolecules and In Vitro Cytotoxicity, Antioxidant and Antimicrobial Activities.
Autorzy :
Adeleke AA; School of Chemistry and Physics, Pietermaritzburg Campus, University of Kwazulu-Natal, Private Bag X01, Scottsville 3209, South Africa.; Department of Chemical Sciences, Olabisi Onabanjo University, P. M. B. 2002, Ago-Iwoye 120107, Nigeria.
Zamisa SJ; School of Chemistry and Physics, Westville Campus, University of Kwazulu-Natal, Private Bag X54001, Westville 4001, South Africa.
Islam MS; Discipline of Biochemistry, School of Life Sciences, Westville Campus, University of Kwazulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Olofinsan K; Discipline of Biochemistry, School of Life Sciences, Westville Campus, University of Kwazulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Salau VF; Discipline of Biochemistry, School of Life Sciences, Westville Campus, University of Kwazulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Mocktar C; Discipline of Pharmaceutical Sciences, School of Health Sciences, Westville Campus, University of Kwazulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Omondi B; School of Chemistry and Physics, Pietermaritzburg Campus, University of Kwazulu-Natal, Private Bag X01, Scottsville 3209, South Africa.
Pokaż więcej
Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 24; Vol. 26 (5). Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antineoplastic Agents/*pharmacology
Antioxidants/*pharmacology
Coordination Complexes/*pharmacology
DNA/*chemistry
Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antioxidants/chemical synthesis ; Antioxidants/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Drug Screening Assays, Antitumor ; Ferric Compounds/antagonists & inhibitors ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Humans ; Microbial Sensitivity Tests ; Oxidation-Reduction ; Quinolines/chemistry ; Quinolines/pharmacology ; Schiff Bases/chemistry ; Schiff Bases/pharmacology ; Silver/chemistry ; Silver/pharmacology
Czasopismo naukowe
Tytuł :
Sulfur-Coordinated Organoiridium(III) Complexes Exert Breast Anticancer Activity via Inhibition of Wnt/β-Catenin Signaling.
Autorzy :
Sun Q; Guangdong Key Laboratory for Genome Stability & Disease Prevention, International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Wang Y; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, P. R. China.; Key Laboratory for Advanced Materials of MOE, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China.
Fu Q; Guangdong Key Laboratory for Genome Stability & Disease Prevention, International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Ouyang A; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, P. R. China.
Liu S; Guangdong Key Laboratory for Genome Stability & Disease Prevention, International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Wang Z; Guangdong Key Laboratory for Genome Stability & Disease Prevention, International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Su Z; Guangdong Key Laboratory for Genome Stability & Disease Prevention, International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Song J; Guangdong Key Laboratory for Genome Stability & Disease Prevention, International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Zhang Q; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, P. R. China.
Zhang P; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, P. R. China.
Lu D; Guangdong Key Laboratory for Genome Stability & Disease Prevention, International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Pokaż więcej
Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Feb 23; Vol. 60 (9), pp. 4841-4848. Date of Electronic Publication: 2021 Jan 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*chemistry
Coordination Complexes/*chemistry
Organometallic Compounds/*chemistry
Sulfur/*chemistry
Wnt Signaling Pathway/*drug effects
Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Survival/drug effects ; Cisplatin/therapeutic use ; Coordination Complexes/pharmacology ; Coordination Complexes/therapeutic use ; Female ; Humans ; Iridium/chemistry ; Low Density Lipoprotein Receptor-Related Protein-6/genetics ; Low Density Lipoprotein Receptor-Related Protein-6/metabolism ; Lung Neoplasms/drug therapy ; Lung Neoplasms/secondary ; Mice ; Mice, Nude ; Transplantation, Heterologous ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
An ER-Targeting Iridium(III) Complex That Induces Immunogenic Cell Death in Non-Small-Cell Lung Cancer.
Autorzy :
Wang L; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Guan R; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Xie L; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Liao X; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Xiong K; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Rees TW; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Chen Y; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Ji L; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Chao H; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Pokaż więcej
Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Feb 23; Vol. 60 (9), pp. 4657-4665. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Coordination Complexes/*chemistry
Endoplasmic Reticulum Stress/*drug effects
Immunogenic Cell Death/*drug effects
Iridium/*chemistry
Adenosine Triphosphate/metabolism ; Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/therapeutic use ; CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Calreticulin/metabolism ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Coordination Complexes/pharmacology ; Coordination Complexes/therapeutic use ; Endoplasmic Reticulum/metabolism ; Female ; HMGB1 Protein/metabolism ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Mice ; Mice, Inbred C57BL ; Reactive Oxygen Species/metabolism ; Survival Rate
Czasopismo naukowe
Tytuł :
Supramolecular Assembly of An Organoplatinum(II) Complex with Ratiometric Dual Emission for Two-Photon Bioimaging.
Autorzy :
Ouyang C; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Li Y; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Rees TW; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Liao X; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Jia J; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Chen Y; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Zhang X; Department of Chemistry, University of Hong Kong, Pokfulam Road, Hong Kong S.A.R., P. R. China.
Ji L; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Chao H; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.; MOE Key Laboratory of Theoretical Organic Chemistry and Functional Molecule, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, 400201, P. R. China.
Pokaż więcej
Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Feb 19; Vol. 60 (8), pp. 4150-4157. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Microscopy, Fluorescence, Multiphoton*
Coordination Complexes/*chemistry
Platinum/*chemistry
Animals ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Coordination Complexes/metabolism ; Coordination Complexes/pharmacology ; Humans ; Inflammation/chemically induced ; Inflammation/diagnostic imaging ; Larva/chemistry ; Larva/metabolism ; Pyridines/chemistry ; Zebrafish/growth & development ; Zebrafish/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies