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Tytuł:
Chemotherapeutic Activities of New η - p -Cymene Ruthenium(II) and Osmium(II) Complexes with Chelating SS and Tridentate SNS Ligands.
Autorzy:
Ywaya DO; School of Chemistry and Physics, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Ibrahim H; School of Chemistry and Physics, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Friedrich HB; School of Chemistry and Physics, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Bala MD; School of Chemistry and Physics, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Soobramoney L; School of Chemistry and Physics, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Daniels A; Nano-Gene and Drug Delivery Group, Discipline of Biochemistry, School of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Singh M; Nano-Gene and Drug Delivery Group, Discipline of Biochemistry, School of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 21; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/chemistry
Antineoplastic Agents*/chemistry
Coordination Complexes*/chemistry
Cymenes*
Humans ; Osmium ; Ligands ; HEK293 Cells ; Thiones ; Chelating Agents/chemistry ; Cell Line, Tumor ; Fluorouracil
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ruthenium-Cyclopentadienyl-Cycloparaphenylene Complexes: Sizable Multicharged Cations Exhibiting High DNA-Binding Affinity and Remarkable Cytotoxicity.
Autorzy:
Ypsilantis K; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Sifnaiou E; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Garypidou A; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Kordias D; Biomedical Research Institute, Foundation for Research and Technology, 45110 Ioannina, Greece.; Laboratory of Clinical Chemistry, Faculty of Medicine, University of Ioannina, 45110 Ioannina, Greece.
Magklara A; Biomedical Research Institute, Foundation for Research and Technology, 45110 Ioannina, Greece.; Laboratory of Clinical Chemistry, Faculty of Medicine, University of Ioannina, 45110 Ioannina, Greece.; Institute of Biosciences, University Research Center of Ioannina (U.R.C.I.), 45110 Ioannina, Greece.
Garoufis A; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.; Institute of Materials Science and Computing, University Research Centre of Ioannina (U.R.C.I.), 45110 Ioannina, Greece.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 19; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/pharmacology
Ruthenium*/chemistry
Ovarian Neoplasms*
Antineoplastic Agents*/chemistry
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Humans ; Female ; Cell Line, Tumor ; Cations ; DNA/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ruthenium(II)-Arene Curcuminoid Complexes as Photosensitizer Agents for Antineoplastic and Antimicrobial Photodynamic Therapy: In Vitro and In Vivo Insights.
Autorzy:
Marras E; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Balacchi CJ; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Orlandi V; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Caruso E; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Brivio MF; Department of Theoretical and Applied Sciences (DiSTA), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Bolognese F; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Mastore M; Department of Theoretical and Applied Sciences (DiSTA), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Malacarne MC; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Rossi M; Department of Chemistry, Vassar College, Poughkeepsie, NY 12604, USA.
Caruso F; Department of Chemistry, Vassar College, Poughkeepsie, NY 12604, USA.
Vivona V; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Ferrario N; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Gariboldi MB; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 11; Vol. 28 (22). Date of Electronic Publication: 2023 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/pharmacology
Ruthenium*/chemistry
Curcumin*/pharmacology
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Antineoplastic Agents*/chemistry
Photochemotherapy*
Humans ; Photosensitizing Agents/chemistry ; Diarylheptanoids ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Investigation of the Relationship between Electronic Structures and Bioactivities of Polypyridyl Ru(II) Complexes.
Autorzy:
Hou Z; Institute of Drug Discovery Technology (IDDT), Ningbo University, Ningbo 315211, China.
Lu Y; Institute of Drug Discovery Technology (IDDT), Ningbo University, Ningbo 315211, China.
Zhang B; Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Research Center, Department of Marine Pharmacy, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315800, China.
Motiur Rahman AFM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Zhao Y; Institute of Drug Discovery Technology (IDDT), Ningbo University, Ningbo 315211, China.
Xi N; Institute of Drug Discovery Technology (IDDT), Ningbo University, Ningbo 315211, China.
Wang N; Institute of Drug Discovery Technology (IDDT), Ningbo University, Ningbo 315211, China.
Wang J; Institute of Drug Discovery Technology (IDDT), Ningbo University, Ningbo 315211, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jun 27; Vol. 28 (13). Date of Electronic Publication: 2023 Jun 27.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/chemistry
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Pyridines/chemistry ; DNA/chemistry ; Density Functional Theory
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An Overview of the Potential Medicinal and Pharmaceutical Properties of Ru(II)/(III) Complexes.
Autorzy:
Skoczynska A; Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, 93-338 Lodz, Poland.
Lewinski A; Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, 93-338 Lodz, Poland.
Pokora M; International Center of Research on Innovative Biobased Materials (ICRI-BioM)-International Research Agenda, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.
Paneth P; International Center of Research on Innovative Biobased Materials (ICRI-BioM)-International Research Agenda, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.; Institute of Applied Radiation Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.
Budzisz E; Department of the Chemistry of Cosmetic Raw Materials, Medical University of Lodz, 90-151 Lodz, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 30; Vol. 24 (11). Date of Electronic Publication: 2023 May 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Coordination Complexes*/pharmacology
Ruthenium*/pharmacology
Diabetes Mellitus, Type 2*
Pharmacy*
Antineoplastic Agents*/pharmacology
Humans ; Pharmaceutical Preparations
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis and Antiproliferative Insights of Lipophilic Ru(II)-Hydroxy Stearic Acid Hybrid Species.
Autorzy:
Drius G; Department of Industrial Chemistry 'Toso Montanari', Alma Mater Studiorum, Università di Bologna, Viale del Risorgimento 4, 40136 Bologna, Italy.
Bordoni S; Department of Industrial Chemistry 'Toso Montanari', Alma Mater Studiorum, Università di Bologna, Viale del Risorgimento 4, 40136 Bologna, Italy.; Health Sciences and Technologies Interdepartmental Centre for Industrial Research (CIRI SDV), University of Bologna, 40126 Bologna, Italy.
Boga C; Department of Industrial Chemistry 'Toso Montanari', Alma Mater Studiorum, Università di Bologna, Viale del Risorgimento 4, 40136 Bologna, Italy.
Monari M; Department of Chemistry 'Giacomo Ciamician', University of Bologna, Via Selmi 2, 40126 Bologna, Italy.
Fiori J; Department of Chemistry 'Giacomo Ciamician', University of Bologna, Via Selmi 2, 40126 Bologna, Italy.
Esposito E; Department of Chemistry 'Giacomo Ciamician', University of Bologna, Via Selmi 2, 40126 Bologna, Italy.; IRCCS, Istituto Scienze Neurologiche di Bologna, Via Altura 1/8, 40139 Bologna, Italy.
Zalambani C; Department of Pharmacy and Biotechnology, University of Bologna, Via San Donato 15, 40127 Bologna, Italy.
Pincigher L; Department of Pharmacy and Biotechnology, University of Bologna, Via San Donato 15, 40127 Bologna, Italy.
Farruggia G; Department of Pharmacy and Biotechnology, University of Bologna, Via San Donato 15, 40127 Bologna, Italy.
Calonghi N; Department of Pharmacy and Biotechnology, University of Bologna, Via San Donato 15, 40127 Bologna, Italy.
Micheletti G; Department of Industrial Chemistry 'Toso Montanari', Alma Mater Studiorum, Università di Bologna, Viale del Risorgimento 4, 40136 Bologna, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 12; Vol. 28 (10). Date of Electronic Publication: 2023 May 12.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Ruthenium*/chemistry
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Humans ; Ligands ; HeLa Cells ; Cell Proliferation ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effective and Selective Ru(II)-Arene Complexes Containing 4,4'-Substituted 2,2' Bipyridine Ligands Targeting Human Urinary Bladder Cancer Cells.
Autorzy:
Muralisankar M; Physics Department, National Dong Hwa University, Hualien 97401, Taiwan.
Chen JR; Physics Department, National Dong Hwa University, Hualien 97401, Taiwan.
Haribabu J; Facultad de Medicina, Universidad de Atacama, Copayapu 485, Copiapo 1531772, Chile.
Ke SC; Physics Department, National Dong Hwa University, Hualien 97401, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 25; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article
MeSH Terms:
Coordination Complexes*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Urinary Bladder Neoplasms*/drug therapy
Ruthenium*/chemistry
Animals ; Humans ; Chlorocebus aethiops ; Cisplatin/pharmacology ; 2,2'-Dipyridyl ; Molecular Docking Simulation ; Ligands ; Vero Cells ; Endothelial Cells/metabolism ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Bipyridine Ruthenium(II) Complexes with Halogen-Substituted Salicylates: Synthesis, Crystal Structure, and Biological Activity.
Autorzy:
Schoeller M; Department of Inorganic Chemistry, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovakia.
Piroš M; Department of Inorganic Chemistry, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovakia.
Litecká M; Department of Materials Chemistry, Institute of Inorganic Chemistry of the CAS, Husinec-Řež č.p. 1001, 250 68 Řež, Czech Republic.
Koňariková K; Institute of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Comenius University, Sasinkova 2, 811 08 Bratislava, Slovakia.
Jozefíková F; Department of Inorganic Chemistry, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovakia.; Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Kalinčiakova 8, 832 32 Bratislava, Slovakia.
Šagátová A; Department of Inorganic Chemistry, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovakia.
Zahradníková E; Department of Inorganic Chemistry, Faculty of Science, Palacký University, 17. Listopadu 12, 771 46 Olomouc, Czech Republic.
Valentová J; Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Kalinčiakova 8, 832 32 Bratislava, Slovakia.
Moncol J; Department of Inorganic Chemistry, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovakia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jun 07; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/pharmacology
Ruthenium*/chemistry
Heterocyclic Compounds*
Coordination Complexes*/chemistry
Antineoplastic Agents*/chemistry
Halogens ; Protein Binding ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mechanistic Studies of Arene-Ruthenium(II) Complexes with Carbothioamidopyrazoles as Alternative Cancer Drugs.
Autorzy:
Hikisz P; Department of Oncobiology and Epigenetics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Namiecińska E; Department of the Chemistry of Cosmetic Raw Materials, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.
Paneth P; Institute of Applied Radiation Chemistry, Department of Chemistry, Technical University of Lodz, Zeromskiego 116, 90-924 Lodz, Poland.
Budzisz E; Department of the Chemistry of Cosmetic Raw Materials, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 08; Vol. 28 (9). Date of Electronic Publication: 2023 May 08.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Ruthenium*/pharmacology
Coordination Complexes*/pharmacology
Neoplasms*
Humans ; Cell Line, Tumor ; Molecular Docking Simulation ; Cisplatin ; Reactive Oxygen Species/metabolism ; Drug Screening Assays, Antitumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ruthenium(II)-Dithiocarbazates as Anticancer Agents: Synthesis, Solution Behavior, and Mitochondria-Targeted Apoptotic Cell Death.
Autorzy:
Sahu G; Department of Chemistry, National Institute of Technology, Rourkela, 769008, Odisha, India.
Patra SA; Department of Chemistry, National Institute of Technology, Rourkela, 769008, Odisha, India.
Lima S; Department of Chemistry, National Institute of Technology, Rourkela, 769008, Odisha, India.; Institut für Anorganische und Analytische Chemie, Friedrich-Schiller-Universität Jena, Humboldtstr. 8, 07743, Jena, Germany.
Das S; Department of Chemistry, National Institute of Technology, Rourkela, 769008, Odisha, India.
Görls H; Institut für Anorganische und Analytische Chemie, Friedrich-Schiller-Universität Jena, Humboldtstr. 8, 07743, Jena, Germany.
Plass W; Institut für Anorganische und Analytische Chemie, Friedrich-Schiller-Universität Jena, Humboldtstr. 8, 07743, Jena, Germany.
Dinda R; Department of Chemistry, National Institute of Technology, Rourkela, 769008, Odisha, India.
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Źródło:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2023 Mar 28; Vol. 29 (18), pp. e202202694. Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Humans ; HeLa Cells ; Apoptosis ; Imines ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exploring pta Alternatives in the Development of Ruthenium-Arene Anticancer Compounds.
Autorzy:
Kljun J; Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, SI-1000 Ljubljana, Slovenia.
Rebernik M; Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, SI-1000 Ljubljana, Slovenia.
Balsa LM; CEQUINOR (UNLP, CCT-CONICET La Plata, Asociado a CIC), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Blvd. 120 N°1465, La Plata 1900, Argentina.
Kladnik J; Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, SI-1000 Ljubljana, Slovenia.
Rapuš U; Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, SI-1000 Ljubljana, Slovenia.
Trobec T; Institute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, Gerbičeva 60, SI-1000 Ljubljana, Slovenia.
Sepčić K; Department of Biology, Biotechnical Faculty, University of LjubljanaJamnikarjeva 101, SI-1000 Ljubljana, Slovenia.
Frangež R; Institute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, Gerbičeva 60, SI-1000 Ljubljana, Slovenia.
León IE; CEQUINOR (UNLP, CCT-CONICET La Plata, Asociado a CIC), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Blvd. 120 N°1465, La Plata 1900, Argentina.
Turel I; Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, SI-1000 Ljubljana, Slovenia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 09; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/pharmacology
Ruthenium*/chemistry
Phosphines*
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Organometallic Compounds*/chemistry
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Ruthenium Compounds ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Recent Trends in the Development of Novel Metal-Based Antineoplastic Drugs.
Autorzy:
Todorov L; Department of Chemistry, Faculty of Pharmacy, Medical University-Sofia, 1504 Sofia, Bulgaria.
Kostova I; Department of Chemistry, Faculty of Pharmacy, Medical University-Sofia, 1504 Sofia, Bulgaria.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 18; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents*
Coordination Complexes*
Transition Elements*
Ruthenium*
Platinum
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Photoactivated Ru (II) Polypyridine Complex Induced Oncotic Necrosis of A549 Cells by Activating Oxidative Phosphorylation and Inhibiting DNA Synthesis as Revealed by Quantitative Proteomics.
Autorzy:
Zhu L; College of Applied Science and Technology, Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing 100101, China.
Liu H; College of Applied Science and Technology, Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing 100101, China.; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Centre for Excellence in Molecular Sciences, National Centre for Mass Spectrometry in Beijing, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Dou Y; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Centre for Excellence in Molecular Sciences, National Centre for Mass Spectrometry in Beijing, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Luo Q; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Centre for Excellence in Molecular Sciences, National Centre for Mass Spectrometry in Beijing, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Gu L; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Centre for Excellence in Molecular Sciences, National Centre for Mass Spectrometry in Beijing, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Liu X; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Centre for Excellence in Molecular Sciences, National Centre for Mass Spectrometry in Beijing, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Zhou Q; Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Han J; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Centre for Excellence in Molecular Sciences, National Centre for Mass Spectrometry in Beijing, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Wang F; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Centre for Excellence in Molecular Sciences, National Centre for Mass Spectrometry in Beijing, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 24; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Ruthenium*/pharmacology
Coordination Complexes*/pharmacology
Humans ; A549 Cells ; Reactive Oxygen Species/metabolism ; Oxidative Phosphorylation ; HEK293 Cells ; Proteomics ; Necrosis ; Apoptosis ; DNA/metabolism ; Adenosine Triphosphate/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Half-Sandwich Type Platinum-Group Metal Complexes of C -Glucosaminyl Azines: Synthesis and Antineoplastic and Antimicrobial Activities.
Autorzy:
Kacsir I; Department of Organic Chemistry, University of Debrecen, P.O. Box 400, H-4002 Debrecen, Hungary.; Doctoral School of Chemistry, University of Debrecen, P.O. Box 400, H-4002 Debrecen, Hungary.
Sipos A; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Egyetem Tér 1., H-4032 Debrecen, Hungary.; The Hungarian Academy of Sciences, Center of Excellence, Hungary.; MTA-DE Cell Biology and Signaling Research Group ELKH, H-4032 Debrecen, Hungary.
Major E; Department of Metagenomics, University of Debrecen, H-4032 Debrecen, Hungary.
Bajusz N; Department of Metagenomics, University of Debrecen, H-4032 Debrecen, Hungary.
Bényei A; Department of Physical Chemistry, Faculty of Sciences and Technology, University of Debrecen, Egyetem Tér 1., H-4032 Debrecen, Hungary.
Buglyó P; Department of Inorganic & Analytical Chemistry, Faculty of Sciences and Technology, University of Debrecen, Egyetem Tér 1., H-4032 Debrecen, Hungary.
Somsák L; Department of Organic Chemistry, University of Debrecen, P.O. Box 400, H-4002 Debrecen, Hungary.
Kardos G; Department of Metagenomics, University of Debrecen, H-4032 Debrecen, Hungary.
Bai P; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Egyetem Tér 1., H-4032 Debrecen, Hungary.; The Hungarian Academy of Sciences, Center of Excellence, Hungary.; MTA-DE Cell Biology and Signaling Research Group ELKH, H-4032 Debrecen, Hungary.; NKFIH-DE Lendület Laboratory of Cellular Metabolism, H-4032 Debrecen, Hungary.; Research Center for Molecular Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Bokor É; Department of Organic Chemistry, University of Debrecen, P.O. Box 400, H-4002 Debrecen, Hungary.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 29; Vol. 28 (7). Date of Electronic Publication: 2023 Mar 29.
Typ publikacji:
Journal Article
MeSH Terms:
Coordination Complexes*/chemistry
Cytostatic Agents*/therapeutic use
Ovarian Neoplasms*/drug therapy
Antineoplastic Agents*/chemistry
Quinolines*/therapeutic use
Anti-Infective Agents*/pharmacology
Anti-Infective Agents*/therapeutic use
Ruthenium*/chemistry
Humans ; Female ; Cell Line, Tumor ; Metals ; Azo Compounds/therapeutic use ; Pyridines/pharmacology ; Pyridines/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
DNA Binding and Cleavage, Stopped-Flow Kinetic, Mechanistic, and Molecular Docking Studies of Cationic Ruthenium(II) Nitrosyl Complexes Containing "NS 4 " Core.
Autorzy:
Shereef HA; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt.; Clinical Pathology Department, University Hospital, Menoufia University, Shebin El-Kom 32512, Egypt.
Moemen YS; Clinical Pathology Department, National Liver Institute, Menoufia University, Shebin El-Kom 32512, Egypt.
Elshami FI; Chemistry Department, Faculty of Science, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
El-Nahas AM; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt.
Shaban SY; Chemistry Department, Faculty of Science, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
van Eldik R; Department of Chemistry and Pharmacy, University of Erlangen-Nuremberg, 91058 Erlangen, Germany.; Faculty of Chemistry, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 28; Vol. 28 (7). Date of Electronic Publication: 2023 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/chemistry
Coordination Complexes*/chemistry
Molecular Docking Simulation ; Ligands ; Nitric Oxide ; DNA/chemistry ; DNA Cleavage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Investigating the Interaction of an Anticancer Nucleolipidic Ru(III) Complex with Human Serum Proteins: A Spectroscopic Study.
Autorzy:
Riccardi C; Department of Chemical Sciences, University Federico II of Napoli, Via Cintia 21, 80126 Napoli, Italy.
Campanella A; Department of Chemical Sciences, University Federico II of Napoli, Via Cintia 21, 80126 Napoli, Italy.
Montesarchio D; Department of Chemical Sciences, University Federico II of Napoli, Via Cintia 21, 80126 Napoli, Italy.; CINMPIS-Consorzio Interuniversitario Nazionale di Ricerca in Metodologie e Processi Innovativi di Sintesi, Via E. Orabona 4, 70125 Bari, Italy.
Del Vecchio P; Department of Chemical Sciences, University Federico II of Napoli, Via Cintia 21, 80126 Napoli, Italy.
Oliva R; Department of Chemical Sciences, University Federico II of Napoli, Via Cintia 21, 80126 Napoli, Italy.
Paduano L; Department of Chemical Sciences, University Federico II of Napoli, Via Cintia 21, 80126 Napoli, Italy.; CSGI-Consorzio Interuniversitario per Lo Sviluppo dei Sistemi a Grande Interfase, Via della Lastruccia 3, 50019 Florence, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 20; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 20.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/chemistry
Coordination Complexes*/chemistry
Antineoplastic Agents*/chemistry
Organometallic Compounds*/chemistry
Humans ; Blood Proteins ; Liposomes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ruthenium(II) Complexes Coupled by Erianin via a Flexible Carbon Chain as a Potential Stabilizer of c-myc G-Quadruplex DNA.
Autorzy:
Wang Z; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Liu W; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Li G; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Wang J; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Zhao B; Department of Southern Pharmacy, Guangdong Jiangmen Chinese Medical, Jiangmen 510047, China.
Huang P; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Mei W; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.; Guangdong Province Engineering Technology Centre for Molecular Probe and Bio-Medical Imaging, Guangzhou 510006, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 04; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 04.
Typ publikacji:
Journal Article
MeSH Terms:
G-Quadruplexes*
Ruthenium*/chemistry
Coordination Complexes*/chemistry
Molecular Docking Simulation ; Phenanthrolines/chemistry ; DNA/chemistry
Czasopismo naukowe
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Tytuł:
Highly Charged Ru(II) Polypyridyl Complexes as Photosensitizer Agents in Photodynamic Therapy of Epithelial Ovarian Cancer Cells.
Autorzy:
Conti L; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Giacomazzo GE; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Valtancoli B; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Perfetti M; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Privitera A; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Giorgi C; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Sfragano PS; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Palchetti I; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Pecchioli S; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
Bruni P; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
Cencetti F; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 01; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:
Journal Article
MeSH Terms:
Photochemotherapy*
Ruthenium*/pharmacology
Ruthenium*/chemistry
Ovarian Neoplasms*/drug therapy
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Humans ; Female ; Photosensitizing Agents/pharmacology ; Photosensitizing Agents/chemistry ; Carcinoma, Ovarian Epithelial/drug therapy ; Cell Line, Tumor ; Reactive Oxygen Species ; HeLa Cells ; Neoplasm Recurrence, Local
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluation of Ruthenium(II) N -Heterocyclic Carbene Complexes as Enzymatic Inhibitory Agents with Antioxidant, Antimicrobial, Antiparasitical and Antiproliferative Activity.
Autorzy:
Al Nasr IS; Department of Biology, College of Science and Arts, Qassim University, Unaizah 51911, Saudi Arabia.; Department of Science Laboratories, College of Science and Arts, Qassim University, Ar Rass 51921, Saudi Arabia.
Koko WS; Department of Science Laboratories, College of Science and Arts, Qassim University, Ar Rass 51921, Saudi Arabia.
Khan TA; Department of Clinical Nutrition, College of Applied Health Sciences, Qassim University, Ar Rass 51921, Saudi Arabia.
Gürbüz N; Department of Chemistry, Faculty of Science and Art, İnönü University, Malatya 44280, Turkey.; Catalysis Research and Application Center, İnönü University, Malatya 44280, Turkey.
Özdemir I; Department of Chemistry, Faculty of Science and Art, İnönü University, Malatya 44280, Turkey.; Catalysis Research and Application Center, İnönü University, Malatya 44280, Turkey.
Hamdi N; Department of Chemistry, College of Science and Arts at ArRass, Qassim University, Ar Rass 51921, Saudi Arabia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jan 31; Vol. 28 (3). Date of Electronic Publication: 2023 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/pharmacology
Ruthenium*/chemistry
Anti-Infective Agents*/pharmacology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Antioxidants/pharmacology ; Ligands
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Metal Complexes of a 5-Nitro-8-Hydroxyquinoline-Proline Hybrid with Enhanced Water Solubility Targeting Multidrug Resistant Cancer Cells.
Autorzy:
Pivarcsik T; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
Pósa V; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
Kovács H; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
May NV; Centre for Structural Science, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.
Spengler G; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Medical Microbiology, Albert Szent-Györgyi Health Center, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis u. 6, H-6725 Szeged, Hungary.
Pósa SP; Drug Resistance Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.; National Laboratory for Drug Research and Development, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.
Tóth S; Drug Resistance Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.; National Laboratory for Drug Research and Development, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.
Nezafat Yazdi Z; Drug Resistance Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.
Özvegy-Laczka C; Drug Resistance Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.
Ugrai I; Institute of Pharmaceutical Chemistry and Stereochemistry Research Group, Eötvös Loránd Research Network, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Szatmári I; Institute of Pharmaceutical Chemistry and Stereochemistry Research Group, Eötvös Loránd Research Network, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Szakács G; Drug Resistance Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.; Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.
Enyedy ÉA; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 29; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 29.
Typ publikacji:
Journal Article
MeSH Terms:
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Ruthenium*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Organometallic Compounds*/chemistry
Neoplasms*
Humans ; Proline ; Solubility ; Ligands ; Drug Resistance, Multiple ; Ferric Compounds ; Drug Resistance, Neoplasm ; Water/chemistry ; Ions ; Ferrous Compounds
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 242

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