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    Wyświetlanie 1-2 z 2
    Tytuł:
    Extensive heterogeneity in somatic mutation and selection in the human bladder.
    Autorzy:
    Lawson ARJ; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Abascal F; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Coorens THH; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Hooks Y; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    O'Neill L; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Latimer C; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Raine K; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Sanders MA; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 GD, Netherlands.
    Warren AY; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
    Mahbubani KTA; Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK.; NIHR Cambridge Biomedical Research Centre, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
    Bareham B; Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK.; NIHR Cambridge Biomedical Research Centre, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
    Butler TM; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Harvey LMR; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Cagan A; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Menzies A; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Moore L; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
    Colquhoun AJ; Department of Urology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
    Turner W; Department of Urology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
    Thomas B; The Royal Melbourne Hospital, Parkville, Victoria 3010, Australia.; Department of Surgery, The University of Melbourne, Parkville, Victoria 3010, Australia.
    Gnanapragasam V; Academic Urology Group, Department of Surgery and Oncology, University of Cambridge, Cambridge CB2 0QQ, UK.; Cambridge Urology Translational Research and Clinical Trials Office, University of Cambridge CB2 0QQ, UK.
    Williams N; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Rassl DM; Department of Pathology, Royal Papworth Hospital NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge CB2 0AY, UK.
    Vöhringer H; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton CB10 1SD, UK.
    Zumalave S; Mobile Genomes and Disease, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, Santiago de Compostela 15706, Spain.
    Nangalia J; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Tubío JMC; Mobile Genomes and Disease, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, Santiago de Compostela 15706, Spain.; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela 15706, Spain.; The Biomedical Research Centre (CINBIO), University of Vigo, Vigo 36310, Spain.
    Gerstung M; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton CB10 1SD, UK.
    Saeb-Parsy K; Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK.; NIHR Cambridge Biomedical Research Centre, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
    Stratton MR; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Campbell PJ; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Department of Haematology, University of Cambridge, Cambridge CB2 2XY, UK.
    Mitchell TJ; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Department of Urology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
    Martincorena I; Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton CB10 1SA, UK. .
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2020 Oct 02; Vol. 370 (6512), pp. 75-82.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genes, Neoplasm*
    Mutagenesis*
    Selection, Genetic*
    Urinary Bladder/*pathology
    Urinary Bladder Neoplasms/*genetics
    Urothelium/*pathology
    APOBEC Deaminases/genetics ; Adult ; Aged ; Biopsy ; Chromatin Assembly and Disassembly/genetics ; Female ; Humans ; Male ; Middle Aged ; Mutagens/analysis ; Mutation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Embryonal precursors of Wilms tumor.
    Autorzy:
    Coorens THH; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Treger TD; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.
    Al-Saadi R; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Moore L; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
    Tran MGB; UCL Division of Surgery and Interventional Science, Royal Free Hospital, London NW3 2PS, UK.; Specialist Centre for Kidney Cancer, Royal Free Hospital, London NW3 2PS, UK.
    Mitchell TJ; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK.
    Tugnait S; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.
    Thevanesan C; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.
    Young MD; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Oliver TRW; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK.
    Oostveen M; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Collord G; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.
    Tarpey PS; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
    Cagan A; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Hooks Y; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Brougham M; Department of Haematology and Oncology, Royal Hospital for Sick Children, Edinburgh EH9 1LF, UK.
    Reynolds BC; Department of Paediatric Nephrology, Royal Hospital for Children, Glasgow G51 4TF, UK.
    Barone G; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Anderson J; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Jorgensen M; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Burke GAA; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.
    Visser J; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
    Nicholson JC; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.
    Smeulders N; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Mushtaq I; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Stewart GD; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK.
    Campbell PJ; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Wedge DC; Big Data Institute, University of Oxford, Oxford OX3 7LF, UK.; Oxford NIHR Biomedical Research Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK.
    Martincorena I; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Rampling D; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Hook L; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK.
    Warren AY; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK.
    Coleman N; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK.
    Chowdhury T; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Sebire N; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Drost J; Princess Máxima Center for Pediatric Oncology, Oncode Institute, 3584 CS Utrecht, Netherlands.
    Saeb-Parsy K; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK.
    Stratton MR; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
    Straathof K; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Pritchard-Jones K; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
    Behjati S; Wellcome Sanger Institute, Hinxton CB10 1SA, UK. .; Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.; Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2019 Dec 06; Vol. 366 (6470), pp. 1247-1251.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Clone Cells*
    DNA Methylation*
    Kidney/*pathology
    Kidney Neoplasms/*genetics
    Precancerous Conditions/*pathology
    Wilms Tumor/*genetics
    Child ; Humans ; Kidney/embryology ; Kidney Neoplasms/pathology ; Mutation ; Phylogeny ; Wilms Tumor/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-2 z 2

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