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Tytuł :
Dendritic cells support a proliferative antigen-specific T-cell response in the presence of poly(lactic-co-glycolic acid).
Autorzy :
Srinivasan S; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA.
Elizabeth Babensee J; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA.; Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA.
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Źródło :
Journal of biomedical materials research. Part A [J Biomed Mater Res A] 2021 Nov; Vol. 109 (11), pp. 2269-2279. Date of Electronic Publication: 2021 May 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adjuvants, Immunologic*/chemistry
Adjuvants, Immunologic*/pharmacology
Antigens*/chemistry
Antigens*/pharmacology
Polylactic Acid-Polyglycolic Acid Copolymer*/chemistry
Polylactic Acid-Polyglycolic Acid Copolymer*/pharmacology
Cell Proliferation/*drug effects
Dendritic Cells/*immunology
T-Lymphocytes/*immunology
Animals ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
A study of lovastatin and L-arginine co-loaded PLGA nanomedicine for enhancing nitric oxide production and eNOS expression.
Autorzy :
Wijaya A; Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing 400030, China. .
Wang Y; College of Basic Medical Sciences, Chongqing Medical University, Chongqing 400016, China.
Tang D; Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing 400030, China. .
Zhong Y; Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing 400030, China. .
Liu B; Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing 400030, China. .
Yan M; Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing 400030, China. .
Jiu Q; Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing 400030, China. .
Wu W; Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing 400030, China. .
Wang G; Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing 400030, China. .
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Źródło :
Journal of materials chemistry. B [J Mater Chem B] 2022 Jan 26; Vol. 10 (4), pp. 607-624. Date of Electronic Publication: 2022 Jan 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nanomedicine*
Arginine/*pharmacology
Atherosclerosis/*drug therapy
Lovastatin/*pharmacology
Nitric Oxide/*biosynthesis
Nitric Oxide Synthase Type III/*genetics
Polylactic Acid-Polyglycolic Acid Copolymer/*pharmacology
Animals ; Arginine/chemistry ; Atherosclerosis/metabolism ; Cells, Cultured ; Humans ; Lovastatin/chemistry ; Male ; Materials Testing ; Mice ; Mice, Inbred C57BL ; Nitric Oxide Synthase Type III/metabolism ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry
Czasopismo naukowe
Tytuł :
High-Efficient Vacuum Ultraviolet-Ozone Assist-Deposited Polydopamine for Poly(lactic- co -glycolic acid)-Coated Pure Zn toward Biodegradable Cardiovascular Stent Applications.
Autorzy :
Fang H; State Key Laboratory of Advanced Welding and Joining, Harbin Institute of Technology, Harbin 150001, China.
Qi X; State Key Laboratory of Advanced Welding and Joining, Harbin Institute of Technology, Harbin 150001, China.
Zhou S; State Key Laboratory of Advanced Welding and Joining, Harbin Institute of Technology, Harbin 150001, China.
Yang S; State Key Laboratory of Advanced Welding and Joining, Harbin Institute of Technology, Harbin 150001, China.
Hang C; State Key Laboratory of Advanced Welding and Joining, Harbin Institute of Technology, Harbin 150001, China.
Tian Y; State Key Laboratory of Advanced Welding and Joining, Harbin Institute of Technology, Harbin 150001, China.
Wang C; State Key Laboratory of Advanced Welding and Joining, Harbin Institute of Technology, Harbin 150001, China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2022 Jan 19; Vol. 14 (2), pp. 3536-3550. Date of Electronic Publication: 2021 Dec 23.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiovascular Diseases/*drug therapy
Coated Materials, Biocompatible/*pharmacology
Indoles/*pharmacology
Ozone/*pharmacology
Polylactic Acid-Polyglycolic Acid Copolymer/*pharmacology
Polymers/*pharmacology
Zinc/*pharmacology
Cell Proliferation/drug effects ; Coated Materials, Biocompatible/chemical synthesis ; Coated Materials, Biocompatible/chemistry ; Hemolysis/drug effects ; Humans ; Indoles/chemistry ; Materials Testing ; Myocytes, Smooth Muscle/drug effects ; Ozone/chemistry ; Particle Size ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Polymers/chemistry ; Stents ; Ultraviolet Rays ; Vacuum ; Zinc/chemistry
Czasopismo naukowe
Tytuł :
Drug delivery of 6-bromoindirubin-3'-glycerol-oxime ether employing poly(D,L-lactide-co-glycolide)-based nanoencapsulation techniques with sustainable solvents.
Autorzy :
Czapka A; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743, Jena, Germany.
Grune C; Pharmaceutical Technology and Biopharmacy, Institute of Pharmacy, Friedrich Schiller University Jena, Lessingstraße 8, 07743, Jena, Germany.
Schädel P; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743, Jena, Germany.
Bachmann V; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743, Jena, Germany.
Scheuer K; Chair of Materials Science (CMS), Faculty of Physics and Astronomy, Otto Schott Institute of Materials Research, Friedrich Schiller University Jena, Löbdergraben 32, 07743, Jena, Germany.
Dirauf M; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
Weber C; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
Skaltsounis AL; Department of Pharmacy, Division of Pharmacognosy and Natural Products Chemistry, University of Athens, Panepistimiopolis Zografou, 15771, Athens, Greece.
Jandt KD; Chair of Materials Science (CMS), Faculty of Physics and Astronomy, Otto Schott Institute of Materials Research, Friedrich Schiller University Jena, Löbdergraben 32, 07743, Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
Schubert US; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
Fischer D; Pharmaceutical Technology and Biopharmacy, Institute of Pharmacy, Friedrich Schiller University Jena, Lessingstraße 8, 07743, Jena, Germany. .; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany. .; Division of Pharmaceutical Technology, Department for Chemistry and Pharmacy, Friedrich-Alexander-University Erlangen-Nürnberg, Cauerstrasse 4, 91058, Erlangen, Germany. .
Werz O; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743, Jena, Germany. .; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany. .
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Źródło :
Journal of nanobiotechnology [J Nanobiotechnology] 2022 Jan 04; Vol. 20 (1), pp. 5. Date of Electronic Publication: 2022 Jan 04.
Typ publikacji :
Journal Article
MeSH Terms :
Indoles*/chemistry
Indoles*/pharmacokinetics
Indoles*/toxicity
Nanoparticle Drug Delivery System*/chemistry
Nanoparticle Drug Delivery System*/pharmacokinetics
Nanoparticle Drug Delivery System*/pharmacology
Oximes*/chemistry
Oximes*/pharmacokinetics
Oximes*/toxicity
Nanoparticles/*chemistry
Polylactic Acid-Polyglycolic Acid Copolymer/*chemistry
Adolescent ; Adult ; Aged ; Animals ; Cell Survival/drug effects ; Fluorescein/chemistry ; Fluorescein/pharmacokinetics ; Humans ; Leukocytes/drug effects ; Middle Aged ; Nanoparticles/toxicity ; Nanotechnology ; Polylactic Acid-Polyglycolic Acid Copolymer/toxicity ; Solvents/chemistry ; Young Adult
Czasopismo naukowe
Tytuł :
Potential of polylactic-co-glycolic acid (PLGA) for delivery Jembrana disease DNA vaccine Model (pEGFP-C1-tat).
Autorzy :
Unsunnidhal L; Department of Reproduction and Obstetrics, Faculty of Veterinary Medicine, University Gadjah Mada, Yogyakarta 55281, Indonesia.; Biomedical Field, Nursing Study Program, STIKES Yarsi Mataram, West Nusa Tenggara 83361, Indonesia.
Wasito R; Department of Pathology, Faculty of Veterinary Medicine, University Gadjah Mada, Yogyakarta 55281, Indonesia.
Nugraha Setyawan EM; Department of Reproduction and Obstetrics, Faculty of Veterinary Medicine, University Gadjah Mada, Yogyakarta 55281, Indonesia.
Warsani Z; Research Center of Biotechnology, University Gadjah Mada, Yogyakarta 55281, Indonesia.
Kusumawati A; Department of Reproduction and Obstetrics, Faculty of Veterinary Medicine, University Gadjah Mada, Yogyakarta 55281, Indonesia.; Department of Pathology, Faculty of Veterinary Medicine, University Gadjah Mada, Yogyakarta 55281, Indonesia. .
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Źródło :
Journal of veterinary science [J Vet Sci] 2021 Nov; Vol. 22 (6), pp. e76. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article
MeSH Terms :
Polylactic Acid-Polyglycolic Acid Copolymer*
Vaccines, DNA*/administration & dosage
Cattle Diseases/*prevention & control
Lentivirus Infections/*veterinary
Viral Vaccines/*administration & dosage
Animals ; Cattle ; Diagnostic Tests, Routine ; HeLa Cells ; Humans ; Lentivirus Infections/prevention & control
Czasopismo naukowe
Tytuł :
Targeted PD-L1 PLGA/liposomes-mediated luteolin therapy for effective liver cancer cell treatment.
Autorzy :
Cao X; Department Of Radiotherapy, Heng Shui City People's Hospital, Hengshui, China.
Wang B; Department Of Radiotherapy, Heng Shui City People's Hospital, Hengshui, China.
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Źródło :
Journal of biomaterials applications [J Biomater Appl] 2021 Nov; Vol. 36 (5), pp. 843-850. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article
MeSH Terms :
B7-H1 Antigen*/drug effects
Liposomes*
Polylactic Acid-Polyglycolic Acid Copolymer*
Liver Neoplasms/*drug therapy
Luteolin/*pharmacology
Animals ; Carcinoma, Hepatocellular ; Cell Line, Tumor ; Cell Movement/drug effects ; Drug Delivery Systems ; Hep G2 Cells ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Luteolin/therapeutic use ; Mice ; Nanoparticles ; Phosphatidylethanolamines ; Polyethylene Glycols
Czasopismo naukowe
Tytuł :
Preparation of Amomum longiligulare polysaccharides 1- PLGA nanoparticle and its immune enhancement ability on RAW264.7 cells.
Autorzy :
Zhou R; Institute of Traditional South Chinese Veterinary Pharmacology, College of Animal Science and Technology, Hainan University, Haikou 570228, PR China.
Teng L; Institute of Traditional South Chinese Veterinary Pharmacology, College of Animal Science and Technology, Hainan University, Haikou 570228, PR China.
Zhu Y; Institute of Traditional South Chinese Veterinary Pharmacology, College of Animal Science and Technology, Hainan University, Haikou 570228, PR China.
Zhang C; Institute of Traditional South Chinese Veterinary Pharmacology, College of Animal Science and Technology, Hainan University, Haikou 570228, PR China.
Yang Y; Institute of Traditional South Chinese Veterinary Pharmacology, College of Animal Science and Technology, Hainan University, Haikou 570228, PR China.
Chen Y; Institute of Traditional South Chinese Veterinary Pharmacology, College of Animal Science and Technology, Hainan University, Haikou 570228, PR China. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2021 Oct; Vol. 99, pp. 108053. Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article
MeSH Terms :
Amomum/*chemistry
Nanoparticles/*chemistry
Plant Preparations/*immunology
Plant Preparations/*pharmacology
Polylactic Acid-Polyglycolic Acid Copolymer/*chemistry
Polysaccharides/*immunology
Polysaccharides/*pharmacology
Animals ; Fruit/chemistry ; Macrophage Activation/drug effects ; Macrophages/drug effects ; Mice ; Nanoparticles/metabolism ; Particle Size ; Phagocytosis/drug effects ; Plant Preparations/chemistry ; Plant Preparations/isolation & purification ; Polylactic Acid-Polyglycolic Acid Copolymer/immunology ; Polylactic Acid-Polyglycolic Acid Copolymer/pharmacology ; Polysaccharides/chemistry ; Polysaccharides/isolation & purification ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł :
Influence of lactide vs glycolide composition of poly (lactic-co-glycolic acid) polymers on encapsulation of hydrophobic molecules: molecular dynamics and formulation studies.
Autorzy :
Dobhal A; Department of Chemical Engineering, Institute of Chemical Technology, Matunga, Mumbai, 400019, India.
Srivastav A; Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga, Mumbai, 400019, India.
Dandekar P; Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga, Mumbai, 400019, India. .
Jain R; Department of Chemical Engineering, Institute of Chemical Technology, Matunga, Mumbai, 400019, India. .
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Źródło :
Journal of materials science. Materials in medicine [J Mater Sci Mater Med] 2021 Sep 30; Vol. 32 (10), pp. 126. Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Carriers*/chemical synthesis
Drug Carriers*/chemistry
Drug Carriers*/pharmacology
Drug Compounding*/methods
Glycolates/*chemistry
Lactic Acid/*chemistry
Polylactic Acid-Polyglycolic Acid Copolymer/*chemistry
Animals ; CHO Cells ; Coumarins/administration & dosage ; Coumarins/pharmacokinetics ; Cricetulus ; Hydrophobic and Hydrophilic Interactions/drug effects ; Materials Testing ; Microscopy, Electron, Transmission ; Molecular Dynamics Simulation ; Nanoparticles/chemistry ; Particle Size ; Polyesters/chemistry ; Polyglycolic Acid/chemistry ; Polylactic Acid-Polyglycolic Acid Copolymer/chemical synthesis ; Polylactic Acid-Polyglycolic Acid Copolymer/pharmacology ; Toxicity Tests
Czasopismo naukowe
Tytuł :
Polyethylenimine (PEI)-modified poly (lactic-co-glycolic) acid (PLGA) nanoparticles conjugated with tumor-homing bacteria facilitate high intensity focused ultrasound-mediated tumor ablation.
Autorzy :
Wang D; State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China; Chongqing Key Laboratory of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Jiang F; State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China; Chongqing Key Laboratory of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Wang L; State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China; Chongqing Key Laboratory of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Tang Y; State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China; Chongqing Key Laboratory of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Zhang Z; State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China; Chongqing Key Laboratory of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Du Y; State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China; Chongqing Key Laboratory of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Zou J; State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China; Chongqing Key Laboratory of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, People's Republic of China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Sep 24; Vol. 571, pp. 104-109. Date of Electronic Publication: 2021 Jul 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Bifidobacterium bifidum/*isolation & purification
Breast Neoplasms/*drug therapy
Breast Neoplasms/*microbiology
Nanoparticles/*chemistry
Polyethyleneimine/*pharmacology
Polylactic Acid-Polyglycolic Acid Copolymer/*pharmacology
Animals ; Antineoplastic Agents/chemistry ; Breast Neoplasms/pathology ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Female ; Mice ; Mice, Inbred BALB C ; Polyethyleneimine/chemistry ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Ultrasonic Waves
Czasopismo naukowe
Tytuł :
Ba/Mg co-doped hydroxyapatite/PLGA composites enhance X-ray imaging and bone defect regeneration.
Autorzy :
Liu X; Department of Spine Surgery, China-Japan Union Hospital of Jilin University, N.126 Xiantai Street, Changchun 130033, Jilin, P. R. China. .
Ma Y
Chen M
Ji J
Zhu Y
Zhu Q
Guo M
Zhang P
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Źródło :
Journal of materials chemistry. B [J Mater Chem B] 2021 Sep 07; Vol. 9 (33), pp. 6691-6702. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Barium/*pharmacology
Biocompatible Materials/*pharmacology
Bone Regeneration/*drug effects
Durapatite/*pharmacology
Magnesium/*pharmacology
Polylactic Acid-Polyglycolic Acid Copolymer/*pharmacology
3T3 Cells ; Animals ; Barium/chemistry ; Biocompatible Materials/chemical synthesis ; Biocompatible Materials/chemistry ; Cells, Cultured ; Durapatite/chemistry ; Magnesium/chemistry ; Male ; Materials Testing ; Mice ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Rats ; Rats, Sprague-Dawley ; Tomography, X-Ray Computed ; X-Rays
Czasopismo naukowe
Tytuł :
An overview of PLGA in-situ forming implants based on solvent exchange technique: effect of formulation components and characterization.
Autorzy :
Ibrahim TM; Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
El-Megrab NA; Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
El-Nahas HM; Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
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Źródło :
Pharmaceutical development and technology [Pharm Dev Technol] 2021 Sep; Vol. 26 (7), pp. 709-728. Date of Electronic Publication: 2021 Jun 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Compounding*/methods
Polylactic Acid-Polyglycolic Acid Copolymer*
Drug Implants/*pharmacokinetics
Humans ; Injections, Intramuscular
Czasopismo naukowe
Tytuł :
Nerve conduit based on HAP/PDLLA/PRGD for peripheral nerve regeneration with sustained release of valproic acid.
Autorzy :
Wu F; Department of Orthopedics, Renmin Hospital, Wuhan University, Wuhan, Hubei, China.
Jiao C; Department of Orthopedics,  Yangxin People's Hospital, Huangshi, Hubei, China.
Yang Y; Department of Orthopedics, Renmin Hospital, Wuhan University, Wuhan, Hubei, China.
Liu F; Department of Orthopedics, Renmin Hospital, Wuhan University, Wuhan, Hubei, China.
Sun Z; Department of Orthopedics, Renmin Hospital, Wuhan University, Wuhan, Hubei, China.
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Źródło :
Cell biology international [Cell Biol Int] 2021 Aug; Vol. 45 (8), pp. 1733-1742. Date of Electronic Publication: 2021 May 03.
Typ publikacji :
Journal Article
MeSH Terms :
Biocompatible Materials/*pharmacokinetics
Durapatite/*pharmacokinetics
Nerve Regeneration/*drug effects
Polylactic Acid-Polyglycolic Acid Copolymer/*pharmacokinetics
Sciatic Nerve/*drug effects
Valproic Acid/*pharmacokinetics
Animals ; Animals, Newborn ; Biocompatible Materials/administration & dosage ; Cells, Cultured ; Delayed-Action Preparations/administration & dosage ; Delayed-Action Preparations/pharmacokinetics ; Drug Liberation/drug effects ; Drug Liberation/physiology ; Durapatite/administration & dosage ; Male ; Nerve Regeneration/physiology ; Polyesters/administration & dosage ; Polyesters/pharmacokinetics ; Polylactic Acid-Polyglycolic Acid Copolymer/administration & dosage ; Rats ; Rats, Wistar ; Schwann Cells/drug effects ; Schwann Cells/metabolism ; Sciatic Nerve/metabolism ; Valproic Acid/administration & dosage
Czasopismo naukowe
Tytuł :
Evaluation of cytotoxic and genotoxic effects of paclitaxel-loaded PLGA nanoparticles in neuroblastoma cells.
Autorzy :
Bacanlı M; University of Health Sciences Turkey, Gülhane Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey. Electronic address: .
Eşi M Ö; University of Health Sciences Turkey, Gülhane Faculty of Pharmacy, Department of Pharmaceutical Technology Ankara, Turkey.
Erdoğan H; University of Health Sciences Turkey, Gülhane Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara, Turkey.
Sarper M; University of Health Sciences Turkey, Gülhane Institute of Health Sciences, Stem Cell Research Center, Ankara, Turkey.
Erdem O; University of Health Sciences Turkey, Gülhane Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey.
Özkan Y; University of Health Sciences Turkey, Gülhane Faculty of Pharmacy, Department of Pharmaceutical Technology Ankara, Turkey.
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2021 Aug; Vol. 154, pp. 112323. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*toxicity
Nanoparticles/*chemistry
Neuroblastoma/*pathology
Paclitaxel/*toxicity
Polylactic Acid-Polyglycolic Acid Copolymer/*chemistry
Antineoplastic Agents, Phytogenic/administration & dosage ; Cell Line, Tumor ; Comet Assay ; Humans ; Nanoparticles/administration & dosage ; Paclitaxel/administration & dosage ; Polylactic Acid-Polyglycolic Acid Copolymer/administration & dosage
Czasopismo naukowe
Tytuł :
Construction of Enzyme-Responsive Micelles Based on Theranostic Zwitterionic Conjugated Bottlebrush Copolymers with Brush-on-Brush Architecture for Cell Imaging and Anticancer Drug Delivery.
Autorzy :
Liu, Fangjun (AUTHOR)
Wang, Dun (AUTHOR)
Wang, Jiaqi (AUTHOR)
Ma, Liwei (AUTHOR)
Yu, Cuiyun (AUTHOR)
Wei, Hua (AUTHOR)
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Źródło :
Molecules. May2022, Vol. 27 Issue 9, p3016-3016. 23p.
Czasopismo naukowe
Tytuł :
Paclitaxel-loaded and folic acid-modified PLGA nanomedicine with glutathione response for the treatment of lung cancer.
Autorzy :
Yao W; Oncology Institute of Traditional Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Yao J; Oncology Institute of Traditional Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Qian F; Oncology Institute of Traditional Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Que Z; Oncology Institute of Traditional Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Yu P; Oncology Institute of Traditional Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Luo T; Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Zheng D; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhang Z; Oncology Institute of Traditional Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Tian J; Oncology Institute of Traditional Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.; Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.; Research Center for Cancer, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China.
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Źródło :
Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2021 Jul 28; Vol. 53 (8), pp. 1027-1036.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Lewis Lung*/drug therapy
Carcinoma, Lewis Lung*/metabolism
Carcinoma, Lewis Lung*/pathology
Folic Acid*/chemistry
Folic Acid*/pharmacokinetics
Folic Acid*/pharmacology
Lung Neoplasms*/drug therapy
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Nanomedicine*
Paclitaxel*/chemistry
Paclitaxel*/pharmacokinetics
Paclitaxel*/pharmacology
Polylactic Acid-Polyglycolic Acid Copolymer*/chemistry
Polylactic Acid-Polyglycolic Acid Copolymer*/pharmacokinetics
Polylactic Acid-Polyglycolic Acid Copolymer*/pharmacology
Glutathione/*metabolism
Animals ; Delayed-Action Preparations/chemistry ; Delayed-Action Preparations/pharmacokinetics ; Delayed-Action Preparations/pharmacology ; Mice
Czasopismo naukowe
Tytuł :
Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours.
Autorzy :
Di Mascolo D; Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.
Palange AL; Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.
Primavera R; Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.; Interventional Regenerative Medicine and Imaging Laboratory, Department of Radiology, Stanford University, Palo Alto, CA, USA.
Macchi F; Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.
Catelani T; Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.; Microscopy Facility, University of Milano-Bicocca, Milan, Italy.
Piccardi F; Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.
Spanò R; Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.
Ferreira M; Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.
Marotta R; Electron Microscopy Facility, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.
Armirotti A; Analytical Chemistry Lab, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.
Gallotti AL; Neural Stem Cell Biology Unit, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy.
Galli R; Neural Stem Cell Biology Unit, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy.
Wilson C; Department of Neurosurgery, Stanford University, Palo Alto, CA, USA.
Grant GA; Department of Neurosurgery, Stanford University, Palo Alto, CA, USA.
Decuzzi P; Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy. .
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Źródło :
Nature nanotechnology [Nat Nanotechnol] 2021 Jul; Vol. 16 (7), pp. 820-829. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Absorbable Implants*
Antineoplastic Combined Chemotherapy Protocols*/pharmacokinetics
Antineoplastic Combined Chemotherapy Protocols*/pharmacology
Polylactic Acid-Polyglycolic Acid Copolymer*/pharmacokinetics
Polylactic Acid-Polyglycolic Acid Copolymer*/pharmacology
Brain Neoplasms/*drug therapy
Animals ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Line ; Diclofenac/pharmacokinetics ; Diclofenac/pharmacology ; Docetaxel/pharmacokinetics ; Docetaxel/pharmacology ; Drug Implants/pharmacokinetics ; Drug Implants/pharmacology ; Female ; Humans ; Mice ; Mice, Nude ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
PLGA Nanoparticles Decorated with Anti-HER2 Affibody for Targeted Delivery and Photoinduced Cell Death.
Autorzy :
Shipunova VO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., 117997 Moscow, Russia.; Institute of Engineering Physics for Biomedicine (PhysBio), MEPhI (Moscow Engineering Physics Institute), 31 Kashirskoe Shosse, 115409 Moscow, Russia.; Moscow Institute of Physics and Technology, 9 Institutskiy per., 141701 Dolgoprudny, Russia.; Department of Nanobiomedicine, Sirius University of Science and Technology, 1 Olympic Ave, 354340 Sochi, Russia.
Sogomonyan AS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., 117997 Moscow, Russia.; Institute of Engineering Physics for Biomedicine (PhysBio), MEPhI (Moscow Engineering Physics Institute), 31 Kashirskoe Shosse, 115409 Moscow, Russia.
Zelepukin IV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., 117997 Moscow, Russia.; Institute of Engineering Physics for Biomedicine (PhysBio), MEPhI (Moscow Engineering Physics Institute), 31 Kashirskoe Shosse, 115409 Moscow, Russia.; Moscow Institute of Physics and Technology, 9 Institutskiy per., 141701 Dolgoprudny, Russia.
Nikitin MP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., 117997 Moscow, Russia.; Moscow Institute of Physics and Technology, 9 Institutskiy per., 141701 Dolgoprudny, Russia.; Department of Nanobiomedicine, Sirius University of Science and Technology, 1 Olympic Ave, 354340 Sochi, Russia.
Deyev SM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., 117997 Moscow, Russia.; Institute of Engineering Physics for Biomedicine (PhysBio), MEPhI (Moscow Engineering Physics Institute), 31 Kashirskoe Shosse, 115409 Moscow, Russia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 28; Vol. 26 (13). Date of Electronic Publication: 2021 Jun 28.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Nanoparticles*/chemistry
Nanoparticles*/therapeutic use
Polylactic Acid-Polyglycolic Acid Copolymer*/chemistry
Polylactic Acid-Polyglycolic Acid Copolymer*/pharmacology
Recombinant Fusion Proteins*/chemistry
Recombinant Fusion Proteins*/pharmacology
Neoplasms/*therapy
Receptor, ErbB-2/*metabolism
A549 Cells ; Animals ; CHO Cells ; Cell Death/drug effects ; Cricetulus ; Humans ; Neoplasms/metabolism ; Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Recombinant ArgF PLGA nanoparticles enhances BCG induced immune responses against Mycobacterium bovis infection.
Autorzy :
Ni J; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Liu Y; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Hussain T; Animal Health, The University of Agriculture Peshawar, 25000, Pakistan.
Li M; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Liang Z; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Liu T; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China. Electronic address: .
Zhou X; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 May; Vol. 137, pp. 111341. Date of Electronic Publication: 2021 Feb 06.
Typ publikacji :
Journal Article
MeSH Terms :
Mycobacterium bovis*/growth & development
Mycobacterium bovis*/pathogenicity
BCG Vaccine/*administration & dosage
BCG Vaccine/*immunology
Nanoparticles/*administration & dosage
Ornithine Carbamoyltransferase/*immunology
Polylactic Acid-Polyglycolic Acid Copolymer/*immunology
Tuberculosis, Bovine/*prevention & control
Administration, Intranasal ; Animals ; Antibody Formation/drug effects ; Body Weight/drug effects ; CD4-Positive T-Lymphocytes/metabolism ; Cattle ; Cell Line ; Disease Models, Animal ; Female ; Immunoglobulin A, Secretory/metabolism ; Immunoglobulin G/blood ; Interferon-gamma/metabolism ; Interleukin-10/blood ; Interleukin-1beta/blood ; Lung/metabolism ; Lung/microbiology ; Lung/pathology ; Macrophages/drug effects ; Macrophages/immunology ; Mice, Inbred BALB C ; Nanoparticles/chemistry ; Ornithine Carbamoyltransferase/administration & dosage ; Ornithine Carbamoyltransferase/chemistry ; Polylactic Acid-Polyglycolic Acid Copolymer/administration & dosage ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/chemistry ; Recombinant Proteins/immunology ; Spleen/microbiology ; Spleen/pathology ; Tumor Necrosis Factor-alpha/blood
Czasopismo naukowe
Tytuł :
Effect of ligand conjugation site on the micellization of Bio-Targeted PLGA-Based nanohybrids: A computational biology approach.
Autorzy :
Khedri M; Computational Biology And Chemistry Group (CBCG), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Rezvantalab S; Department of Chemical Engineering, Urmia University of Technology, Urmia, Iran.
Maleki R; Computational Biology And Chemistry Group (CBCG), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Rezaei N; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2022 Jul; Vol. 40 (10), pp. 4409-4418. Date of Electronic Publication: 2020 Dec 18.
Typ publikacji :
Journal Article
MeSH Terms :
Nanoparticles*/chemistry
Polyglycolic Acid*/chemistry
Computational Biology ; Drug Carriers/chemistry ; Lactic Acid/chemistry ; Ligands ; Molecular Docking Simulation ; Polyethylene Glycols/chemistry ; Polylactic Acid-Polyglycolic Acid Copolymer
Czasopismo naukowe

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