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Tytuł :
[Inhibition of Copper Transporter-1 by Ammonium Tetrathiocarbolybdate in the Treatment of Pancreatic Cancer].
Autorzy :
Zhao YN; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Chen LH; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Yang XL; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Dong JY; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Wu WB; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Chen D; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Geng RM; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Ke NW; Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Liu J; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
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Źródło :
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition [Sichuan Da Xue Xue Bao Yi Xue Ban] 2020 Sep; Vol. 51 (5), pp. 643-649.
Typ publikacji :
Journal Article
MeSH Terms :
Ammonium Compounds*
Chelating Agents*/pharmacology
Copper Transporter 1*/metabolism
Copper Transporter 1*/pharmacology
Pancreatic Neoplasms*/drug therapy
Animals ; Cell Line, Tumor ; Cell Proliferation ; Copper ; Humans ; Mice ; Mice, Nude ; Vascular Endothelial Growth Factor A/metabolism
SCR Disease Name :
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł :
Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function.
Autorzy :
Sudhahar V; Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, Georgia.; Department of Pharmacology and Toxicology, Medical College of Georgia at Augusta University, Augusta, Georgia.; Charlie Norwood Veterans Affairs Medical Center, Augusta, Georgia.
Okur MN; Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.
O'Bryan JP; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina.; Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina.
Minshall RD; Departments of Anesthesiology and Pharmacology, University of Illinois at Chicago, Chicago, Illinois.
Fulton D; Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, Georgia.; Department of Pharmacology and Toxicology, Medical College of Georgia at Augusta University, Augusta, Georgia.
Ushio-Fukai M; Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, Georgia.; Department of Medicine (Cardiology), Medical College of Georgia at Augusta University, Augusta, Georgia.
Fukai T; Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, Georgia.; Department of Pharmacology and Toxicology, Medical College of Georgia at Augusta University, Augusta, Georgia.; Charlie Norwood Veterans Affairs Medical Center, Augusta, Georgia.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2020 Nov 01; Vol. 319 (5), pp. C933-C944. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Caveolin 1/*genetics
Copper-Transporting ATPases/*genetics
Endothelial Cells/*metabolism
Superoxide Dismutase/*genetics
Superoxide Dismutase-1/*genetics
Animals ; Aorta/cytology ; Aorta/metabolism ; Caveolin 1/deficiency ; Copper/pharmacology ; Copper Transport Proteins/genetics ; Copper Transport Proteins/metabolism ; Copper-Transporting ATPases/metabolism ; Endothelial Cells/cytology ; Endothelial Cells/drug effects ; Fibroblasts/cytology ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Gene Expression Regulation ; Male ; Mesenteric Arteries/cytology ; Mesenteric Arteries/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Oxidative Stress ; Primary Cell Culture ; Proteasome Endopeptidase Complex/metabolism ; Proteolysis ; Signal Transduction ; Superoxide Dismutase/metabolism ; Superoxide Dismutase-1/metabolism ; Ubiquitination/drug effects ; Vasodilation/drug effects
Czasopismo naukowe
Tytuł :
The Response of the Planorbid Snail Isidorella newcombi to Chronic Copper Exposure Over a 28-Day Period: Linking Mortality, Cellular Biomarkers, and Reproductive Responses.
Autorzy :
Ubrihien RP; Centre for Applied Water Science, University of Canberra, Canberra, ACT, 2601, Australia. .
Maher WA; Research School of Earth Science, Australian National University, Canberra, ACT, 2601, Australia.
Taylor AM; Centre for Applied Water Science, University of Canberra, Canberra, ACT, 2601, Australia.
Stevens MM; NSW Department of Primary Industries, Yanco Agricultural Institute, Private Mail Bag, Yanco, NSW, 2703, Australia.; Graham Centre for Agricultural Innovation, NSW Department of Primary Industries and Charles Sturt University, North Wagga Wagga, NSW, Australia.
Ezaz T; Centre for Conservation Ecology and Genetics, University of Canberra, Canberra, ACT, 2601, Australia.
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Źródło :
Archives of environmental contamination and toxicology [Arch Environ Contam Toxicol] 2020 Nov; Vol. 79 (4), pp. 391-405. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
MeSH Terms :
Copper/*toxicity
Snails/*physiology
Water Pollutants, Chemical/*toxicity
Animals ; Biomarkers ; Copper/analysis ; Copper Sulfate ; Fresh Water ; Reproduction ; Toxicity Tests, Chronic ; Water Pollutants, Chemical/analysis
Czasopismo naukowe
Tytuł :
Mechanism of CuSO 4 cytotoxicity in goat erythrocytes after high-level in vitro exposure to isotonic media.
Autorzy :
Tao D; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China.
Wang Y; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China.
Liu J; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China.
Chen R; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China.
Qi M; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China.
Xu S; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China; Key Laboratory of Tarim Animal Husbandry Technology Corps, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Jan 15; Vol. 208, pp. 111730. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article
MeSH Terms :
Copper Sulfate/*toxicity
Hazardous Substances/*toxicity
Adenosine Triphosphatases/metabolism ; Animals ; Antioxidants/metabolism ; Copper/analysis ; Erythrocyte Membrane/chemistry ; Erythrocyte Membrane/drug effects ; Erythrocyte Membrane/metabolism ; Erythrocytes/drug effects ; Goats/metabolism ; Hemolysis/drug effects ; Osmotic Fragility/drug effects ; Oxidative Stress/drug effects ; Phospholipids/analysis ; Toxicity Tests
Czasopismo naukowe
Tytuł :
Relative Risk of Cervical Neoplasms Among Copper and Levonorgestrel-Releasing Intrauterine System Users.
Autorzy :
Sel G; Zonguldak Bulent Ecevit University, Zonguldak, Turkey.
Yaşar O
Aynali B
Dinçer F
Novruzova K
Darka İ
Akdemir AY
Harma M
Harma Mİ
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Źródło :
Obstetrics and gynecology [Obstet Gynecol] 2020 Jun; Vol. 135 (6), pp. 1486-1487.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Intrauterine Devices, Copper*/adverse effects
Intrauterine Devices, Medicated*/adverse effects
Uterine Cervical Neoplasms*/epidemiology
Copper ; Female ; Humans ; Levonorgestrel/adverse effects ; Risk
Czasopismo naukowe
Tytuł :
Copper mediates mitochondrial biogenesis in retinal pigment epithelial cells.
Autorzy :
Aloysius Dhivya M; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India; SASTRA deemed to be University, Trichy - Tanjore Road, Thirumalaisamudram, Thanjavur, Tamil Nadu 613401, India.
Aberami S; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India.
Nikhalashree S; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India; SASTRA deemed to be University, Trichy - Tanjore Road, Thirumalaisamudram, Thanjavur, Tamil Nadu 613401, India.
Biswas J; Department of Uveitis, Medical Research Foundation, India.
Liu W; Department of Bioengineering, Cancer Center at Illinois, Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Irudayaraj J; Department of Bioengineering, Cancer Center at Illinois, Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Sulochana KN; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India.
Coral K; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India. Electronic address: .
Bharathi Devi SR; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Oct 01; Vol. 1866 (10), pp. 165843. Date of Electronic Publication: 2020 May 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Organelle Biogenesis*
Copper/*metabolism
Epithelial Cells/*metabolism
Macular Degeneration/*metabolism
Mitochondria/*metabolism
Retinal Pigment Epithelium/*metabolism
Retinal Pigments/*metabolism
Aged ; Aged, 80 and over ; Cell Line ; Choroid/metabolism ; Copper/pharmacology ; Copper Transporter 1/metabolism ; DNA-Binding Proteins/metabolism ; Electron Transport Complex IV/metabolism ; Female ; Gene Expression Regulation/drug effects ; Humans ; Macular Degeneration/pathology ; Male ; Mitochondria/genetics ; Mitochondrial Proteins/metabolism ; Molecular Chaperones/metabolism ; NF-E2-Related Factor 2/metabolism ; RNA, Messenger/metabolism ; RNA-Binding Proteins/metabolism ; Reactive Oxygen Species/metabolism ; Retinal Pigment Epithelium/pathology ; Retinal Pigments/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Activation of HIF-1 signaling ameliorates liver steatosis in zebrafish atp7b deficiency (Wilson's disease) models.
Autorzy :
Mi X; Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Li Z; Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Yan J; Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Li Y; School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Zheng J; Department of Pathology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Zhuang Z; Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Yang W; Department of Pathology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Gong L; Department of Infectious Disease, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Shi J; Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China; Department of Infectious Disease, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Oct 01; Vol. 1866 (10), pp. 165842. Date of Electronic Publication: 2020 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Copper-Transporting ATPases/*genetics
Fatty Liver/*metabolism
Hepatolenticular Degeneration/*genetics
Hepatolenticular Degeneration/*metabolism
Hypoxia-Inducible Factor 1/*metabolism
Liver/*metabolism
Signal Transduction/*physiology
Zebrafish Proteins/*genetics
Animals ; CRISPR-Cas Systems ; Copper/metabolism ; Copper/toxicity ; Disease Models, Animal ; Fatty Liver/genetics ; Fatty Liver/pathology ; Female ; Gene Knockout Techniques ; Hep G2 Cells ; Hepatocytes/metabolism ; Humans ; Liver/pathology ; Male ; Mutation ; Zebrafish
Czasopismo naukowe
Tytuł :
Effects of soybean oil and dietary copper levels on nutrient digestion, ruminal fermentation, enzyme activity, microflora and microbial protein synthesis in dairy bulls.
Autorzy :
Shang X; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Wang C; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Zhang G; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Liu Q; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Guo G; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Huo W; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Zhang J; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Pei C; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
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Źródło :
Archives of animal nutrition [Arch Anim Nutr] 2020 Aug; Vol. 74 (4), pp. 257-270. Date of Electronic Publication: 2019 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Digestion*
Bacteria/*metabolism
Cattle/*physiology
Copper Sulfate/*metabolism
Rumen/*enzymology
Rumen/*microbiology
Soybean Oil/*metabolism
Animal Feed/analysis ; Animals ; Bacterial Proteins/biosynthesis ; Copper/administration & dosage ; Copper/metabolism ; Copper Sulfate/administration & dosage ; Dairying ; Diet/veterinary ; Dietary Supplements/analysis ; Fermentation ; Gastrointestinal Microbiome/physiology ; Male ; Nutrients/physiology ; Soybean Oil/administration & dosage
Czasopismo naukowe
Tytuł :
Integration of transcriptomic and metabolomic data reveals metabolic pathway alteration in mouse spermatogonia with the effect of copper exposure.
Autorzy :
Lin S; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China; Department of Histology and Embryology, Anhui Medicial University, Hefei, 230032, China.
Qiao N; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Chen H; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Tang Z; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Han Q; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Mehmood K; University College of Veterinary & Animal Sciences, Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Fazlani SA; Lasbela University of Agriculture Water & Marine Sciences, Uthal Balochistan Pakistan, Pakistan.
Hameed S; University College of Veterinary & Animal Sciences, Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Li Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. Electronic address: .
Zhang H; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2020 Oct; Vol. 256, pp. 126974. Date of Electronic Publication: 2020 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Copper/*toxicity
Environmental Pollutants/*toxicity
Spermatogonia/*drug effects
Animals ; Copper Sulfate/pharmacology ; Down-Regulation/drug effects ; Male ; Metabolic Networks and Pathways ; Metabolomics ; Mice ; Transcriptome/drug effects ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Antagonistic bioaccumulation of waterborne Cu(II) and Cd(II) in common carp (Cyprinus carpio) and effects on ion-homeostasis and defensive mechanisms.
Autorzy :
Castaldo G; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium. Electronic address: .
Flipkens G; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
Pillet M; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
Town RM; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
Bervoets L; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
Blust R; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
De Boeck G; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
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Źródło :
Aquatic toxicology (Amsterdam, Netherlands) [Aquat Toxicol] 2020 Sep; Vol. 226, pp. 105561. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article
MeSH Terms :
Bioaccumulation/*drug effects
Cadmium/*toxicity
Carps/*metabolism
Copper/*toxicity
Homeostasis/*drug effects
Water Pollutants, Chemical/*toxicity
Animals ; Cadmium/metabolism ; Carps/genetics ; Copper/metabolism ; Copper Transporter 1/genetics ; Copper Transporter 1/metabolism ; Electrolytes/metabolism ; Gills/drug effects ; Gills/metabolism ; Ion Transport ; Lethal Dose 50 ; Potassium/metabolism ; Sodium/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism ; Water Pollutants, Chemical/metabolism
Czasopismo naukowe
Tytuł :
Analysis of Wilson disease mutations revealed that interactions between different ATP7B mutants modify their properties.
Autorzy :
Roy S; Department of Physiology, Johns Hopkins Medical Institute, Baltimore, MD, USA. .; S. N. Pradhan Centre for Neurosciences, University of Calcutta, Kolkata, India. .
McCann CJ; Department of Physiology, Johns Hopkins Medical Institute, Baltimore, MD, USA.
Ralle M; Oregon Health and Science University, Portland, OR, USA.
Ray K; ATGC Diagnostics Private Ltd, Kolkata, India.
Ray J; S. N. Pradhan Centre for Neurosciences, University of Calcutta, Kolkata, India.
Lutsenko S; Department of Physiology, Johns Hopkins Medical Institute, Baltimore, MD, USA. .
Jayakanthan S; Department of Physiology, Johns Hopkins Medical Institute, Baltimore, MD, USA.
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Źródło :
Scientific reports [Sci Rep] 2020 Aug 10; Vol. 10 (1), pp. 13487. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Copper-Transporting ATPases/*genetics
Hepatolenticular Degeneration/*genetics
Adenosine Triphosphatases/metabolism ; Alleles ; Cation Transport Proteins/genetics ; Copper/metabolism ; Copper-Transporting ATPases/metabolism ; Endoplasmic Reticulum/metabolism ; Genetic Association Studies ; HEK293 Cells ; Humans ; Mutation ; Protein Transport ; trans-Golgi Network/genetics ; trans-Golgi Network/metabolism
Czasopismo naukowe
Tytuł :
ATP7B variant penetrance explains differences between genetic and clinical prevalence estimates for Wilson disease.
Autorzy :
Wallace DF; Institute of Health and Biomedical Innovation and School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia. .
Dooley JS; Division of Medicine, UCL Institute for Liver and Digestive Health, University College London Medical School (Royal Free Campus), London, UK.
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Źródło :
Human genetics [Hum Genet] 2020 Aug; Vol. 139 (8), pp. 1065-1075. Date of Electronic Publication: 2020 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Copper-Transporting ATPases/*genetics
Genetic Variation/*genetics
Hepatolenticular Degeneration/*genetics
Copper/metabolism ; Databases, Nucleic Acid ; Gene Frequency ; Hepatolenticular Degeneration/epidemiology ; Humans ; Penetrance ; Prevalence
Czasopismo naukowe
Tytuł :
Melatonin: A hypothesis regarding its use to treat Wilson disease.
Autorzy :
Sharma R; Department of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, TX 78229, USA. Electronic address: .
Reiter RJ; Department of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, TX 78229, USA.
Ma Q; Department of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, TX 78229, USA.
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Źródło :
Medical hypotheses [Med Hypotheses] 2019 Dec; Vol. 133, pp. 109408. Date of Electronic Publication: 2019 Sep 24.
Typ publikacji :
Journal Article
MeSH Terms :
Chelation Therapy*
Copper*/metabolism
Antioxidants/*therapeutic use
Chelating Agents/*therapeutic use
Hepatolenticular Degeneration/*drug therapy
Melatonin/*therapeutic use
Animals ; Antioxidants/pharmacology ; Bile/metabolism ; Brain/drug effects ; Brain/metabolism ; Brain/pathology ; Butyrates/metabolism ; Butyrates/therapeutic use ; Chelating Agents/pharmacology ; Copper-Transporting ATPases/deficiency ; Copper-Transporting ATPases/genetics ; Dose-Response Relationship, Drug ; Endoplasmic Reticulum Stress/drug effects ; Female ; Gastrointestinal Microbiome ; Hepatolenticular Degeneration/genetics ; Humans ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Liver Cirrhosis/etiology ; Liver Cirrhosis/prevention & control ; Male ; Melatonin/adverse effects ; Melatonin/pharmacology ; Mitochondria/metabolism
Czasopismo naukowe
Tytuł :
Biochemical regulation and structural analysis of copper-transporting ATPase in a human hepatoma cell line for Wilson disease.
Autorzy :
Agnihotry S; Department of Computational Biology and Bioinformatics, Jacob Institute of Biotechnology and Bio-Engineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad, Uttar Pradesh, India.
Dhusia K; Department of Computational Biology and Bioinformatics, Jacob Institute of Biotechnology and Bio-Engineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad, Uttar Pradesh, India.
Srivastav AK; Photobiology Laboratory, System Toxicology and Health Risk Assessment Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow, Uttar Pradesh, India.
Upadhyay J; Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Verma V; Department of Hematology, Stem Cell Research Centre, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Shukla PK; Department of Biological Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad, Uttar Pradesh, India.
Ramteke PW; Department of Biological Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad, Uttar Pradesh, India.
Gautam B; Department of Computational Biology and Bioinformatics, Jacob Institute of Biotechnology and Bio-Engineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad, Uttar Pradesh, India.
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Źródło :
Journal of cellular biochemistry [J Cell Biochem] 2019 Nov; Vol. 120 (11), pp. 18826-18844. Date of Electronic Publication: 2019 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular*/enzymology
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/pathology
Copper-Transporting ATPases*/genetics
Copper-Transporting ATPases*/metabolism
Hepatolenticular Degeneration*
Liver Neoplasms*/enzymology
Liver Neoplasms*/genetics
Liver Neoplasms*/pathology
Models, Biological*
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Apoptosis ; Copper/metabolism ; DNA Damage ; Hep G2 Cells ; Humans ; Mutation ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Quantitation of copper chlorophylls in green table olives by ultra-high-performance liquid chromatography with inductively coupled plasma isotope dilution mass spectrometry.
Autorzy :
Harp BP; Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, 5001 Campus Drive, College Park, MD, 20740, USA.
Scholl PF; Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, 5001 Campus Drive, College Park, MD, 20740, USA.
Gray PJ; Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, 5001 Campus Drive, College Park, MD, 20740, USA.
Delmonte P; Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, 5001 Campus Drive, College Park, MD, 20740, USA. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2020 Jun 07; Vol. 1620, pp. 461008. Date of Electronic Publication: 2020 Mar 03.
Typ publikacji :
Journal Article
MeSH Terms :
Chlorophyll/*analysis
Chromatography, High Pressure Liquid/*methods
Copper/*analysis
Mass Spectrometry/*methods
Copper Sulfate/chemistry ; Hydrophobic and Hydrophilic Interactions ; Indicator Dilution Techniques ; Isotopes ; Olea/chemistry ; Porphyrins/chemistry ; Sodium/analysis
Czasopismo naukowe
Tytuł :
WilsonGen a comprehensive clinically annotated genomic variant resource for Wilson's Disease.
Autorzy :
Kumar M; CSIR Institute of Genomics and Integrative Biology, Mathura Road, Delhi, 110 025, India.; Academy of Scientific and Innovative Research, CSIR-IGIB South Campus, Mathura Road, Delhi, India.
Gaharwar U; CSIR Institute of Genomics and Integrative Biology, Mathura Road, Delhi, 110 025, India.
Paul S; CSIR Institute of Genomics and Integrative Biology, Mathura Road, Delhi, 110 025, India.; Academy of Scientific and Innovative Research, CSIR-IGIB South Campus, Mathura Road, Delhi, India.
Poojary M; CSIR Institute of Genomics and Integrative Biology, Mathura Road, Delhi, 110 025, India.; Academy of Scientific and Innovative Research, CSIR-IGIB South Campus, Mathura Road, Delhi, India.
Pandhare K; CSIR Institute of Genomics and Integrative Biology, Mathura Road, Delhi, 110 025, India.
Scaria V; CSIR Institute of Genomics and Integrative Biology, Mathura Road, Delhi, 110 025, India. .; Academy of Scientific and Innovative Research, CSIR-IGIB South Campus, Mathura Road, Delhi, India. .
Bk B; CSIR Institute of Genomics and Integrative Biology, Mathura Road, Delhi, 110 025, India. .; Academy of Scientific and Innovative Research, CSIR-IGIB South Campus, Mathura Road, Delhi, India. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jun 03; Vol. 10 (1), pp. 9037. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Dataset; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Copper-Transporting ATPases/*genetics
Genetic Variation/*genetics
Hepatolenticular Degeneration/*genetics
Alleles ; Copper/metabolism ; Copper-Transporting ATPases/metabolism ; Databases, Genetic ; Genetic Testing/methods ; Genomics/methods ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Mutation/genetics
Czasopismo naukowe
Tytuł :
Copper bioavailability, uptake, toxicity and tolerance in plants: A comprehensive review.
Autorzy :
Kumar V; Department of Botany, Government Degree College, Ramban, Jammu, 182144, India. Electronic address: .
Pandita S; Department of Botany, University of Jammu, Jammu and Kashmir, India.
Singh Sidhu GP; Centre for Applied Biology in Environment Sciences, Kurukshetra University, Kurukshetra, 136119, India.
Sharma A; State Key Laboratory of Subtropical Silviculture, Zhejiang A & F University, Hangzhou, 311300, China.
Khanna K; Independent Researcher, House No.282, Lane no. 3, Friends Colony, Opposite DAV College, Jalandhar, 144008, Punjab, India.
Kaur P; Independent Researcher, House No. 472, Ward No. 8, Dhariwal, Gurdaspur, 143519, Punjab, India.
Bali AS; Department of Botany, Dyal Singh College, Karnal, Haryana, 132001, India.
Setia R; Punjab Remote Sensing Centre, Ludhiana, India.
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Źródło :
Chemosphere [Chemosphere] 2021 Jan; Vol. 262, pp. 127810. Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Copper/*metabolism
Crops, Agricultural/*physiology
Soil Pollutants/*metabolism
Biological Availability ; Copper/analysis ; Copper/toxicity ; Crops, Agricultural/metabolism ; Heavy Metal Poisoning ; Humans ; Soil/chemistry ; Soil Pollutants/analysis ; Soil Pollutants/toxicity
Czasopismo naukowe
Tytuł :
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer.
Autorzy :
Aubert L; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada.
Nandagopal N; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada.
Steinhart Z; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, ON, M5S 3M2, Canada.
Lavoie G; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada.
Nourreddine S; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada.
Berman J; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, 600 University Ave., Toronto, ON, M5G 1X5, Canada.
Saba-El-Leil MK; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada.
Papadopoli D; Department of Oncology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, 3755 Côte Sainte-Catherine Road, Montreal, QC, H3T 1E2, Canada.
Lin S; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, ON, M5S 3M2, Canada.
Hart T; MD Anderson Cancer Center, University of Texas, 515 Holcombe Blvd, Houston, TX, 77030, USA.
Macleod G; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, ON, M5S 3M2, Canada.
Topisirovic I; Department of Oncology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, 3755 Côte Sainte-Catherine Road, Montreal, QC, H3T 1E2, Canada.
Gaboury L; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada.; Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Fahrni CJ; School of Chemistry and Biochemistry, Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 315 Ferst Dr NW, Atlanta, GA, 30332, USA.
Schramek D; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, 600 University Ave., Toronto, ON, M5G 1X5, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Meloche S; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada.; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Angers S; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, ON, M5S 3M2, Canada.; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Roux PP; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada. .; Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada. .
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Źródło :
Nature communications [Nat Commun] 2020 Jul 24; Vol. 11 (1), pp. 3701. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Colorectal Neoplasms/*metabolism
Copper/*metabolism
Proto-Oncogene Proteins p21(ras)/*genetics
Proto-Oncogene Proteins p21(ras)/*metabolism
Animals ; Biological Availability ; CRISPR-Cas Systems ; Cell Line, Tumor ; Cell Proliferation ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Copper-Transporting ATPases/metabolism ; Female ; Humans ; Intestinal Mucosa/pathology ; Mice ; Mice, Knockout ; Mice, Nude ; Mice, SCID ; Mutation
Czasopismo naukowe
Tytuł :
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice.
Autorzy :
Guthrie LM; Department of Molecular and Cellular Medicine, Texas A&M Health Science Center, College Station, TX 77843, USA.
Soma S; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Yuan S; Department of Animal and Avian Sciences, University of Maryland, College Park, MD 20742, USA.
Silva A; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Zulkifli M; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Snavely TC; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Greene HF; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Nunez E; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Lynch B; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
De Ville C; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Shanbhag V; Department of Biochemistry, University of Missouri, Columbia, MO 65211, USA.
Lopez FR; Texas Veterinary Medicine Diagnostic Laboratory, College Station, TX 77843, USA.
Acharya A; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Petris MJ; Department of Biochemistry, University of Missouri, Columbia, MO 65211, USA.
Kim BE; Department of Animal and Avian Sciences, University of Maryland, College Park, MD 20742, USA.
Gohil VM; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA. .
Sacchettini JC; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA. .
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Źródło :
Science (New York, N.Y.) [Science] 2020 May 08; Vol. 368 (6491), pp. 620-625.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Copper/*metabolism
Hydrazines/*therapeutic use
Menkes Kinky Hair Syndrome/*drug therapy
Animals ; Biological Transport/drug effects ; Brain/metabolism ; Brain/pathology ; Cell Line ; Copper Transporter 1/genetics ; Disease Models, Animal ; Electron Transport Complex IV/metabolism ; Hydrazines/pharmacology ; Male ; Menkes Kinky Hair Syndrome/metabolism ; Menkes Kinky Hair Syndrome/pathology ; Mice ; Mice, Knockout ; Mitochondria/metabolism ; Neurodegenerative Diseases/prevention & control ; Rats
Czasopismo naukowe
Tytuł :
Interactive effect of compost application and inoculation with the fungus Claroideoglomus claroideum in Oenothera picensis plants growing in mine tailings.
Autorzy :
Pérez R; Centro de Investigación en Micorrizas y Sustentabilidad Agroambiental, CIMYSA, Universidad de La Frontera, Avenida Francisco Salazar 01145, Temuco, Chile; Programa de Doctorado en Ciencias de Recursos Naturales, Universidad de La Frontera, Temuco, Chile.
Tapia Y; Departamento de Ingeniería y Suelos, Universidad de Chile, 8820808 Santiago, Chile.
Antilén M; Departamento de Química Inorgánica, Pontificia Universidad Católica de Chile, 7820436 Santiago, Chile.
Casanova M; Departamento de Ingeniería y Suelos, Universidad de Chile, 8820808 Santiago, Chile.
Vidal C; Centro de Investigación en Micorrizas y Sustentabilidad Agroambiental, CIMYSA, Universidad de La Frontera, Avenida Francisco Salazar 01145, Temuco, Chile; Programa de Doctorado en Ciencias de Recursos Naturales, Universidad de La Frontera, Temuco, Chile.
Santander C; Centro de Investigación en Micorrizas y Sustentabilidad Agroambiental, CIMYSA, Universidad de La Frontera, Avenida Francisco Salazar 01145, Temuco, Chile.
Aponte H; Centro de Investigación en Micorrizas y Sustentabilidad Agroambiental, CIMYSA, Universidad de La Frontera, Avenida Francisco Salazar 01145, Temuco, Chile; Laboratory of Soil Microbiology and Biogeochemistry, Institute of Agri-Food, Animal and Environmental Sciences (ICA3), Universidad de O'Higgins, San Fernando, Chile.
Cornejo P; Centro de Investigación en Micorrizas y Sustentabilidad Agroambiental, CIMYSA, Universidad de La Frontera, Avenida Francisco Salazar 01145, Temuco, Chile. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Jan 15; Vol. 208, pp. 111495. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article
MeSH Terms :
Composting/*methods
Copper/*metabolism
Fungi/*physiology
Oenothera/*microbiology
Soil Pollutants/*metabolism
Biodegradation, Environmental ; Biomass ; Copper/analysis ; Fungi/metabolism ; Mining ; Mycorrhizae/metabolism ; Mycorrhizae/physiology ; Oenothera/growth & development ; Oenothera/metabolism ; Soil/chemistry ; Soil Pollutants/analysis
SCR Organism :
Claroideoglomus claroideum
Czasopismo naukowe

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