Reduced endosomal microautophagy activity in aging associates with enhanced exocyst-mediated protein secretion.
Autorzy:
Krause GJ; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA.; Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, New York, USA. Diaz A; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA.; Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, New York, USA. Jafari M; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA.; Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, New York, USA. Khawaja RR; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA.; Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, New York, USA. Agullo-Pascual E; Microscopy and Advanced Bioimaging Core, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Santiago-Fernández O; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA.; Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, New York, USA. Richards AL; Department of Cellular Molecular Pharmacology, University of California San Francisco, San Francisco, California, USA.; The J. David Gladstone Institutes, San Francisco, California, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, California, USA. Chen KH; Department of Cellular Molecular Pharmacology, University of California San Francisco, San Francisco, California, USA.; The J. David Gladstone Institutes, San Francisco, California, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, California, USA. Dmitriev P; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA.; Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, New York, USA. Sun Y; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA. See SK; Department of Biochemistry and Biophysics, Institute for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, California, USA. Abdelmohsen K; Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, Maryland, USA. Mazan-Mamczarz K; Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, Maryland, USA. Krogan NJ; Department of Cellular Molecular Pharmacology, University of California San Francisco, San Francisco, California, USA.; The J. David Gladstone Institutes, San Francisco, California, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, California, USA. Gorospe M; Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, Maryland, USA. Swaney DL; Department of Cellular Molecular Pharmacology, University of California San Francisco, San Francisco, California, USA.; The J. David Gladstone Institutes, San Francisco, California, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, California, USA. Sidoli S; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA. Bravo-CorderoJJ; Department of Medicine, Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Kampmann M; Department of Biochemistry and Biophysics, Institute for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, California, USA. Cuervo AM; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA.; Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, New York, USA.
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Źródło:
Aging cell [Aging Cell] 2022 Oct; Vol. 21 (10), pp. e13713. Date of Electronic Publication: 2022 Sep 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Effects of electret coating technology on coronary stent thrombogenicity.
Autorzy:
Zafar MU; Department of Medicine, AtheroThrombosis Research Unit (ATRU), Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, USA. Bravo-CorderoJJ; Division of Hematology and Oncology, Department of Medicine, the Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA. Torramade-Moix S; Hemostasis Coagulation Unit, Department of Pathology, Hospital Clinic De Barcelona, Barcelona, Spain. Escolar G; Department of Medicine, AtheroThrombosis Research Unit (ATRU), Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, USA.; Hemostasis Coagulation Unit, Department of Pathology, Hospital Clinic De Barcelona, Barcelona, Spain. Jerez-Dolz D; Hemostasis Coagulation Unit, Department of Pathology, Hospital Clinic De Barcelona, Barcelona, Spain. Lev EI; Assuta Ashdod University Hospital, Ashdod, and the Faculty of Health Sciences, Ben-Gurion University, Israel. Badimon JJ; Department of Medicine, AtheroThrombosis Research Unit (ATRU), Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
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Źródło:
Platelets [Platelets] 2022 Feb 17; Vol. 33 (2), pp. 312-319. Date of Electronic Publication: 2021 Apr 15.
TMEM176B Regulates AKT/mTOR Signaling and Tumor Growth in Triple-Negative Breast Cancer.
Autorzy:
Kang C; Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1055, New York, NY 10029, USA. Rostoker R; Diabetes and Metabolism Clinical Research Center of Excellence, Clinical Research Institute at Rambam (CRIR) and the Faculty of Medicine, Technion, Rambam Medical Center, Haifa 31096, Israel. Ben-Shumel S; Diabetes and Metabolism Clinical Research Center of Excellence, Clinical Research Institute at Rambam (CRIR) and the Faculty of Medicine, Technion, Rambam Medical Center, Haifa 31096, Israel. Rashed R; Diabetes and Metabolism Clinical Research Center of Excellence, Clinical Research Institute at Rambam (CRIR) and the Faculty of Medicine, Technion, Rambam Medical Center, Haifa 31096, Israel. Duty JA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Center of Therapeutic Antibody Development, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Demircioglu D; The Bioinformatic for Next Generation Sequencing (BiNGS) Core, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Antoniou IM; Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1055, New York, NY 10029, USA. Isakov L; Diabetes and Metabolism Clinical Research Center of Excellence, Clinical Research Institute at Rambam (CRIR) and the Faculty of Medicine, Technion, Rambam Medical Center, Haifa 31096, Israel. Shen-Orr Z; Diabetes and Metabolism Clinical Research Center of Excellence, Clinical Research Institute at Rambam (CRIR) and the Faculty of Medicine, Technion, Rambam Medical Center, Haifa 31096, Israel. Bravo-CorderoJJ; Division of Hematology and Oncology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Kase N; Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1055, New York, NY 10029, USA. Cuajungco MP; Biological Science, California State University, Fullerton, CA 92831, USA. Moran TM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Center of Therapeutic Antibody Development, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. LeRoith D; Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1055, New York, NY 10029, USA.; Center of Therapeutic Antibody Development, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Gallagher EJ; Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1055, New York, NY 10029, USA.; Center of Therapeutic Antibody Development, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
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Źródło:
Cells [Cells] 2021 Dec 06; Vol. 10 (12). Date of Electronic Publication: 2021 Dec 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Remodeling the ECM: Implications for Metastasis and Tumor Dormancy.
Autorzy:
Di Martino JS; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Akhter T; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Bravo-CorderoJJ; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
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Źródło:
Cancers [Cancers (Basel)] 2021 Sep 30; Vol. 13 (19). Date of Electronic Publication: 2021 Sep 30.
Pleckstrin-2 is essential for erythropoiesis in β-thalassemic mice, reducing apoptosis and enhancing enucleation.
Autorzy:
Feola M; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; University of Piemonte Orientale, Amedeo Avogadro, Novara, Italy. Zamperone A; Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY, USA. Moskop D; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Chen H; Erythropoiesis Laboratory, New York Blood Center, New York, NY, USA.; Hunan Province Key Laboratory of Basic and Applied Hematology, School of Life Sciences, Central South University, Changsha, China. Casu C; Children's Hospital of Philadelphia, Philadelphia, PA, USA. Lama D; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Di Martino J; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Djedaini M; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Papa L; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Martinez MR; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Choesang T; Erythropoiesis Laboratory, New York Blood Center, New York, NY, USA. Bravo-CorderoJJ; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. MacKay M; Weill Cornell Medical College, New York, NY, USA. Zumbo P; Weill Cornell Medical College, New York, NY, USA. Brinkman N; CSL Behring, Kankakee, IL, USA. Abrams CS; Perelman Center for Advanced Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. Rivella S; Children's Hospital of Philadelphia, Philadelphia, PA, USA. Hattangadi S; Yale University, New Haven, CT, USA. Mason CE; Weill Cornell Medical College, New York, NY, USA. Hoffman R; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Ji P; Northwestern University, Chicago, IL, USA. Follenzi A; University of Piemonte Orientale, Amedeo Avogadro, Novara, Italy. Ginzburg YZ; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .
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Źródło:
Communications biology [Commun Biol] 2021 May 03; Vol. 4 (1), pp. 517. Date of Electronic Publication: 2021 May 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/Mena -initiated invadopodium formation.
Autorzy:
Pignatelli J; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States.; Gruss Lipper Biophotonics Center Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Bravo-CorderoJJ; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States.; Gruss Lipper Biophotonics Center Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Roh-Johnson M; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States.; Gruss Lipper Biophotonics Center Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Gandhi SJ; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Wang Y; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States.; Gruss Lipper Biophotonics Center Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Chen X; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Eddy RJ; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Xue A; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Singer RH; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Hodgson L; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States.; Gruss Lipper Biophotonics Center Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Oktay MH; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States.; Department of Pathology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States. Condeelis JS; Department of Anatomy and Structural Biology Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States.; Gruss Lipper Biophotonics Center Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, United States.
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Źródło:
Scientific reports [Sci Rep] 2016 Nov 30; Vol. 6, pp. 37874. Date of Electronic Publication: 2016 Nov 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Roh-Johnson M; 1] Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, USA [2] Gruss-Lipper Biophotonics Center, Bronx, NY, USA. Bravo-CorderoJJ; 1] Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, USA [2] Gruss-Lipper Biophotonics Center, Bronx, NY, USA. Patsialou A; 1] Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, USA [2] Gruss-Lipper Biophotonics Center, Bronx, NY, USA. Sharma VP; 1] Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, USA [2] Gruss-Lipper Biophotonics Center, Bronx, NY, USA. Guo P; 1] Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, USA [2] Gruss-Lipper Biophotonics Center, Bronx, NY, USA. Liu H; The Ben May Department for Cancer Research, University of Chicago, Chicago, IL, USA. Hodgson L; 1] Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, USA [2] Gruss-Lipper Biophotonics Center, Bronx, NY, USA. Condeelis J; 1] Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, USA [2] Gruss-Lipper Biophotonics Center, Bronx, NY, USA.
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Źródło:
Oncogene [Oncogene] 2014 Aug 14; Vol. 33 (33), pp. 4203-12. Date of Electronic Publication: 2013 Sep 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.
Autorzy:
Moshfegh Y; 1] Department of Anatomy and Structural Biology, Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA [2]. Bravo-CorderoJJ; 1] Department of Anatomy and Structural Biology, Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA [2]. Miskolci V; Department of Anatomy and Structural Biology, Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA. Condeelis J; Department of Anatomy and Structural Biology, Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA. Hodgson L; Department of Anatomy and Structural Biology, Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA.
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Źródło:
Nature cell biology [Nat Cell Biol] 2014 Jun; Vol. 16 (6), pp. 574-86. Date of Electronic Publication: 2014 May 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Video-Audio Media
Functions of cofilin in cell locomotion and invasion.
Autorzy:
Bravo-CorderoJJ; Department of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, 1300 Morris Park Avenue, Bronx, New York 10461, USA. />Magalhaes MA Eddy RJ Hodgson L Condeelis J
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