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Wyszukujesz frazę ""Cornall, Richard J."" wg kryterium: Autor


Wyświetlanie 1-14 z 14
Tytuł:
NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance.
Autorzy:
Hodgson R; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Xu X; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Anzilotti C; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Deobagkar-Lele M; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Crockford TL; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Kepple JD; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Cawthorne E; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Bhandari A; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Cebrian-Serrano A; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Wilcock MJ; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Davies B; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Cornall RJ; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. richard.cornall@ndm.ox.ac.uk.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. richard.cornall@ndm.ox.ac.uk.
Bull KR; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. .; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. .
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Źródło:
Communications biology [Commun Biol] 2022 Nov 10; Vol. 5 (1), pp. 1216. Date of Electronic Publication: 2022 Nov 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Refsum Disease*/genetics
Refsum Disease*/metabolism
Charcot-Marie-Tooth Disease*/genetics
Mice ; Animals ; T-Lymphocytes ; Immune Tolerance ; Lymphocyte Activation
Czasopismo naukowe
Tytuł:
Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections.
Autorzy:
Eyre DW; Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, UK. .; Oxford University Hospitals NHS Foundation Trust, Oxford, UK. .; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. .; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford in partnership with Public Health England, Oxford, UK. .; Microbiology Department, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK. .
Lumley SF; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
O'Donnell D; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Stoesser NE; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford in partnership with Public Health England, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Matthews PC; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Howarth A; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Hatch SB; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Marsden BD; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Kennedy Institute of Rheumatology Research, University of Oxford, Oxford, UK.
Cox S; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
James T; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Cornall RJ; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Stuart DI; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Screaton G; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Ebner D; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Target Discovery Institute, University of Oxford, Oxford, UK.
Crook DW; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Conlon CP; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Jeffery K; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Walker TM; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Peto TEA; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2021 Feb 18; Vol. 21 (1), pp. 187. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Viral/*analysis
COVID-19/*diagnosis
COVID-19 Serological Testing/*standards
Immunoglobulin G/*analysis
Adult ; Ageusia/virology ; Anosmia/virology ; Asymptomatic Infections ; Enzyme-Linked Immunosorbent Assay/standards ; Female ; Health Personnel ; Humans ; Immunoassay/standards ; Male ; Middle Aged ; Sensitivity and Specificity ; Undiagnosed Diseases ; United Kingdom
Czasopismo naukowe
Tytuł:
Mutations in TCF12, encoding a basic helix-loop-helix partner of TWIST1, are a frequent cause of coronal craniosynostosis.
Autorzy:
Sharma VP; Clinical Genetics Group, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Fenwick AL
Brockop MS
McGowan SJ
Goos JA
Hoogeboom AJ
Brady AF
Jeelani NO
Lynch SA
Mulliken JB
Murray DJ
Phipps JM
Sweeney E
Tomkins SE
Wilson LC
Bennett S
Cornall RJ
Broxholme J
Kanapin A
Johnson D
Wall SA
van der Spek PJ
Mathijssen IM
Maxson RE
Twigg SR
Wilkie AO
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Corporate Authors:
500 Whole-Genome Sequences (WGS500) Consortium
Źródło:
Nature genetics [Nat Genet] 2013 Mar; Vol. 45 (3), pp. 304-7. Date of Electronic Publication: 2013 Jan 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Craniosynostoses*/complications
Craniosynostoses*/genetics
Craniosynostoses*/pathology
Basic Helix-Loop-Helix Transcription Factors/*genetics
Nuclear Proteins/*genetics
Twist-Related Protein 1/*genetics
Acrocephalosyndactylia/complications ; Acrocephalosyndactylia/genetics ; Acrocephalosyndactylia/pathology ; Animals ; Cranial Sutures/growth & development ; Cranial Sutures/pathology ; Dimerization ; Exome ; Gene Expression Regulation, Developmental ; Heterozygote ; Humans ; Mice ; Mice, Transgenic ; Molecular Sequence Data ; Mutation ; Sequence Analysis, DNA ; Transcriptional Activation
Czasopismo naukowe
Tytuł:
Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations.
Autorzy:
Bull KR; Nuffield Department of Medicine and Wellcome Trust Centre for Human Genetics, Oxford University, Oxford, United Kingdom.
Rimmer AJ
Siggs OM
Miosge LA
Roots CM
Enders A
Bertram EM
Crockford TL
Whittle B
Potter PK
Simon MM
Mallon AM
Brown SD
Beutler B
Goodnow CC
Lunter G
Cornall RJ
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Źródło:
PLoS genetics [PLoS Genet] 2013; Vol. 9 (1), pp. e1003219. Date of Electronic Publication: 2013 Jan 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Models, Animal*
Genome*
Ethylnitrosourea/*toxicity
Mutation/*genetics
Sequence Analysis, DNA/*methods
Animals ; Chromosome Mapping ; Genes, Dominant ; Genes, Recessive ; Humans ; Mice ; Mutagenesis ; Phenotype
Czasopismo naukowe
Tytuł:
The phenotype of circulating follicular-helper T cells in patients with rheumatoid arthritis defines CD200 as a potential therapeutic target.
Autorzy:
Chakera A; School of Medicine and Pharmacology, Sir Charles Gairdner Hospital, The University of Western Australia, 4th Floor G Block, Hospital Avenue, Nedlands, Perth, WA 6009, Australia.
Bennett SC
Morteau O
Bowness P
Luqmani RA
Cornall RJ
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Źródło:
Clinical & developmental immunology [Clin Dev Immunol] 2012; Vol. 2012, pp. 948218. Date of Electronic Publication: 2012 Oct 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD/*immunology
Arthritis, Rheumatoid/*blood
Arthritis, Rheumatoid/*immunology
T-Lymphocytes, Helper-Inducer/*immunology
Adult ; Aged ; Aged, 80 and over ; Autoantibodies/immunology ; Autoimmunity/immunology ; Case-Control Studies ; Female ; Humans ; Interferon-gamma/immunology ; Male ; Middle Aged ; Phenotype ; Tumor Necrosis Factor-alpha/immunology ; Young Adult
Czasopismo naukowe
Tytuł:
A whole blood monokine-based reporter assay provides a sensitive and robust measurement of the antigen-specific T cell response.
Autorzy:
Chakera A; richard.cornall@ndm.ox.ac.uk
Bennett SC
Cornall RJ
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Źródło:
Journal of translational medicine [J Transl Med] 2011 Aug 26; Vol. 9, pp. 143. Date of Electronic Publication: 2011 Aug 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Enzyme-Linked Immunospot Assay/*methods
Monokines/*blood
T-Cell Antigen Receptor Specificity/*immunology
T-Lymphocytes/*immunology
Cells, Cultured ; Humans ; Immunosuppression Therapy ; Interferon-gamma/pharmacology ; Lymphocyte Activation/drug effects ; Lymphocyte Activation/immunology ; Lymphocyte Count ; Receptors, Cytokine/genetics ; Receptors, Cytokine/metabolism ; Recombinant Proteins/pharmacology ; Reproducibility of Results ; Sensitivity and Specificity ; T-Lymphocytes/drug effects
Czasopismo naukowe
Tytuł:
Renal transplant immunosuppression impairs natural killer cell function in vitro and in vivo.
Autorzy:
Morteau O; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
Blundell S
Chakera A
Bennett S
Christou CM
Mason PD
Cornall RJ
O'Callaghan CA
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Źródło:
PloS one [PLoS One] 2010 Oct 12; Vol. 5 (10), pp. e13294. Date of Electronic Publication: 2010 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:
Kidney Transplantation*
Cyclosporine/*therapeutic use
Immunosuppressive Agents/*therapeutic use
Killer Cells, Natural/*drug effects
Tacrolimus/*therapeutic use
Cell Degranulation/drug effects ; Cyclosporine/pharmacology ; Flow Cytometry ; Humans ; Immunosuppressive Agents/pharmacology ; In Vitro Techniques ; Interferon-gamma/biosynthesis ; Tacrolimus/pharmacology
Czasopismo naukowe
Tytuł:
Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection.
Autorzy:
Johnson AL; Nuffield Department of Clinical Medicine, Oxford University, UK.
Aravind L
Shulzhenko N
Morgun A
Choi SY
Crockford TL
Lambe T
Domaschenz H
Kucharska EM
Zheng L
Vinuesa CG
Lenardo MJ
Goodnow CC
Cornall RJ
Schwartz RH
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Źródło:
Nature immunology [Nat Immunol] 2009 Aug; Vol. 10 (8), pp. 831-9. Date of Electronic Publication: 2009 Jul 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
Cell Lineage/*physiology
Proteins/*physiology
Receptors, Antigen, T-Cell/*physiology
Amino Acid Sequence ; Animals ; CD4-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/cytology ; Cell Differentiation ; Cell Line ; Cell Survival/physiology ; Ethylnitrosourea/pharmacology ; Female ; Humans ; Intercellular Signaling Peptides and Proteins ; Mice ; Molecular Sequence Data ; Mutation ; Oligonucleotide Array Sequence Analysis ; Proteins/genetics ; Proteins/immunology ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/immunology ; Signal Transduction
Czasopismo naukowe
Tytuł:
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis.
Autorzy:
Heazlewood CK; Mucin and IBD Research Teams, Mucosal Diseases Program, Mater Medical Research Institute, and the University of Queensland, Aubigny Place, Mater Health Services, South Brisbane, Queensland, Australia.
Cook MC
Eri R
Price GR
Tauro SB
Taupin D
Thornton DJ
Png CW
Crockford TL
Cornall RJ
Adams R
Kato M
Nelms KA
Hong NA
Florin TH
Goodnow CC
McGuckin MA
Pokaż więcej
Źródło:
PLoS medicine [PLoS Med] 2008 Mar 04; Vol. 5 (3), pp. e54.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colitis, Ulcerative/*metabolism
Colitis, Ulcerative/*pathology
Endoplasmic Reticulum/*pathology
Mucins/*metabolism
Adult ; Animals ; Apoptosis ; Cell Proliferation ; Colitis, Ulcerative/genetics ; Colitis, Ulcerative/immunology ; Endoplasmic Reticulum/ultrastructure ; Gene Expression Regulation ; Genetic Predisposition to Disease ; Goblet Cells/pathology ; Humans ; Inflammation ; Intestinal Mucosa/pathology ; Intestinal Mucosa/ultrastructure ; Male ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Mucin-2 ; Mucins/chemistry ; Mucins/genetics ; Mutation/genetics ; Protein Folding ; Protein Precursors/metabolism ; Protein Structure, Quaternary
Czasopismo naukowe
Tytuł:
DNA repair is limiting for haematopoietic stem cells during ageing.
Autorzy:
Nijnik A; Henry Wellcome Building for Molecular Physiology, Oxford University, Oxford OX3 9DU, UK.
Woodbine L
Marchetti C
Dawson S
Lambe T
Liu C
Rodrigues NP
Crockford TL
Cabuy E
Vindigni A
Enver T
Bell JI
Slijepcevic P
Goodnow CC
Jeggo PA
Cornall RJ
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Źródło:
Nature [Nature] 2007 Jun 07; Vol. 447 (7145), pp. 686-90.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Repair*
Aging/*physiology
Hematopoietic Stem Cells/*cytology
Animals ; Cell Proliferation ; Cellular Senescence/physiology ; DNA Breaks, Double-Stranded ; DNA Damage ; DNA Ligase ATP ; DNA Ligases/deficiency ; DNA Ligases/genetics ; DNA Ligases/metabolism ; Hematopoietic Stem Cells/pathology ; Humans ; Mice ; Mice, Inbred C57BL ; Mutation, Missense/drug effects ; Mutation, Missense/genetics ; Syndrome
Czasopismo naukowe
Tytuł:
Tolerance and autoimmunity in the eye: a role for CD8 T cells in organ-specific autoimmunity in the retina.
Autorzy:
Forrester JV; Department of Ophthalmology, University of Aberdeen, UK. j. />Cornall RJ
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Źródło:
Immunology [Immunology] 2003 Nov; Vol. 110 (3), pp. 293-5.
Typ publikacji:
Comment; Journal Article; Review
MeSH Terms:
Autoimmunity*
Immune Tolerance*
CD8-Positive T-Lymphocytes/*immunology
Retina/*immunology
Animals ; CD4-Positive T-Lymphocytes/immunology ; Humans
Czasopismo naukowe
    Wyświetlanie 1-14 z 14

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