NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance.
Autorzy:
Hodgson R; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Xu X; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Anzilotti C; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Deobagkar-Lele M; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Crockford TL; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Kepple JD; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, Oxford, UK. Cawthorne E; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Bhandari A; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Cebrian-Serrano A; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Wilcock MJ; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Davies B; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. CornallRJ; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. richard.cornall@ndm.ox.ac.uk.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. richard.cornall@ndm.ox.ac.uk. Bull KR; MRC Human Immunology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. .; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. .
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Źródło:
Communications biology [Commun Biol] 2022 Nov 10; Vol. 5 (1), pp. 1216. Date of Electronic Publication: 2022 Nov 10.
Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections.
Autorzy:
Eyre DW; Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, UK. .; Oxford University Hospitals NHS Foundation Trust, Oxford, UK. .; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. .; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford in partnership with Public Health England, Oxford, UK. .; Microbiology Department, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK. . Lumley SF; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK. O'Donnell D; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Stoesser NE; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford in partnership with Public Health England, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Matthews PC; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Howarth A; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Hatch SB; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Marsden BD; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Kennedy Institute of Rheumatology Research, University of Oxford, Oxford, UK. Cox S; Oxford University Hospitals NHS Foundation Trust, Oxford, UK. James T; Oxford University Hospitals NHS Foundation Trust, Oxford, UK. CornallRJ; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Stuart DI; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Screaton G; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Ebner D; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Target Discovery Institute, University of Oxford, Oxford, UK. Crook DW; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Conlon CP; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Jeffery K; Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Walker TM; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam. Peto TEA; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2021 Feb 18; Vol. 21 (1), pp. 187. Date of Electronic Publication: 2021 Feb 18.
The phenotype of circulating follicular-helper T cells in patients with rheumatoid arthritis defines CD200 as a potential therapeutic target.
Autorzy:
Chakera A; School of Medicine and Pharmacology, Sir Charles Gairdner Hospital, The University of Western Australia, 4th Floor G Block, Hospital Avenue, Nedlands, Perth, WA 6009, Australia. Bennett SC Morteau O Bowness P Luqmani RA CornallRJ
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