Temat: "Coronavirus Nucleocapsid Proteins" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Colorimetric and Raman dual-mode lateral flow immunoassay detection of SARS-CoV-2 N protein antibody based on Ag nanoparticles with ultrathin Au shell assembled onto Fe 3 O 4 nanoparticles.
Autorzy:: Li J; College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao, 266580, People's Republic of China.
Liang P; College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao, 266580, People's Republic of China.
Zhao T; College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao, 266580, People's Republic of China.
Guo G; College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao, 266580, People's Republic of China.
Zhu J; College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao, 266580, People's Republic of China.
Wen C; College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao, 266580, People's Republic of China. .
Zeng J; College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao, 266580, People's Republic of China. .; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2023 Feb; Vol. 415 (4), pp. 545-554. Date of Electronic Publication: 2022 Nov 22.
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19*/diagnosis
Gold*
Metal Nanoparticles*
SARS-CoV-2*/immunology
Silver*
Coronavirus Nucleocapsid Proteins*/immunology
Antibodies, Viral*/analysis
Humans ; Colorimetry ; COVID-19 Testing ; Immunoassay ; Reproducibility of Results ; Spectrum Analysis, Raman

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Skocz do pozycji: 2.

Tytuł:: Folic acid: a potential inhibitor against SARS-CoV-2 nucleocapsid protein.
Autorzy:: Chen YM; Laboratory of Tissue and Cell Biology, Lab Teaching & Management Center, Chongqing Medical University, Chongqing, PR China.
Wei JL; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China.
Qin RS; Laboratory of Tissue and Cell Biology, Lab Teaching & Management Center, Chongqing Medical University, Chongqing, PR China.
Hou JP; General Surgery of Neonatal Surgery, Liangjiang District, Children's Hospital of Chongqing Medical University, Chongqing, PR China.
Zang GC; Laboratory of Tissue and Cell Biology, Lab Teaching & Management Center, Chongqing Medical University, Chongqing, PR China.
Zhang GY; Laboratory of Tissue and Cell Biology, Lab Teaching & Management Center, Chongqing Medical University, Chongqing, PR China.; Pathogen Biology and Immunology Laboratory, Lab Teaching & Management Center, Chongqing Medical University, Chongqing, PR China.
Chen TT; Laboratory of Tissue and Cell Biology, Lab Teaching & Management Center, Chongqing Medical University, Chongqing, PR China.; Pathogen Biology and Immunology Laboratory, Lab Teaching & Management Center, Chongqing Medical University, Chongqing, PR China.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 862-878.
Typ publikacji:: Journal Article
MeSH Terms:: Coronavirus Nucleocapsid Proteins*/antagonists & inhibitors
Folic Acid*/pharmacology
SARS-CoV-2*
COVID-19 Drug Treatment*
Humans ; Molecular Docking Simulation ; Phosphoproteins/antagonists & inhibitors

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Skocz do pozycji: 3.

Tytuł:: Structural dynamics of SARS-CoV-2 nucleocapsid protein induced by RNA binding.
Autorzy:: Ribeiro-Filho HV; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Jara GE; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Batista FAH; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Schleder GR; Brazilian Nanotechnology National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Costa Tonoli CC; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Soprano AS; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Guimarães SL; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Borges AC; Brazilian Nanotechnology National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Cassago A; Brazilian Nanotechnology National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Bajgelman MC; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Marques RE; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Trivella DBB; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Franchini KG; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Figueira ACM; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Benedetti CE; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.
Lopes-de-Oliveira PS; Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2022 May 12; Vol. 18 (5), pp. e1010121. Date of Electronic Publication: 2022 May 12 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Coronavirus Nucleocapsid Proteins*/chemistry
Coronavirus Nucleocapsid Proteins*/metabolism
SARS-CoV-2*/chemistry
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19 ; Humans ; Microscopy, Electron ; Molecular Dynamics Simulation ; Nucleocapsid Proteins/chemistry ; Nucleocapsid Proteins/metabolism ; Phosphoproteins/metabolism ; Protein Binding ; RNA, Viral/genetics

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Skocz do pozycji: 4.

Tytuł:: Crystal structures of the SARS-CoV-2 nucleocapsid protein C-terminal domain and development of nucleocapsid-targeting nanobodies.
Autorzy:: Jia Z; The First Affiliated Hospital, Biomedical Translational Research Institute and Guangdong Province Key Laboratory of Molecular Immunology and Antibody Engineering, Jinan University, Guangzhou, China.; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, China.; International Research Center for precision medicine, Beroni Group Limited, Sydney, Australia.
Liu C; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, China.
Chen Y; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, China.
Jiang H; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, China.
Wang Z; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, China.
Yao J; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, China.
Yang J; International Research Center for precision medicine, Beroni Group Limited, Sydney, Australia.
Zhu J; International Research Center for precision medicine, Beroni Group Limited, Sydney, Australia.
Zhang B; International Research Center for precision medicine, Beroni Group Limited, Sydney, Australia.
Yuchi Z; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, China.; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2022 Jul; Vol. 289 (13), pp. 3813-3825. Date of Electronic Publication: 2021 Oct 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Coronavirus Nucleocapsid Proteins*/chemistry
Single-Domain Antibodies*/chemistry
Amino Acid Sequence ; Nucleocapsid/chemistry ; Phosphoproteins/chemistry ; SARS-CoV-2

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Skocz do pozycji: 5.

Tytuł:: Anti-nucleocapsid antibodies enhance the production of IL-6 induced by SARS-CoV-2 N protein.
Autorzy:: Nakayama EE; Research Institute for Microbial Diseases and Center for Infectious Disease Education and Research, Osaka University, Suita, Osaka, 565-0871, Japan. .
Kubota-Koketsu R; Research Institute for Microbial Diseases and Center for Infectious Disease Education and Research, Osaka University, Suita, Osaka, 565-0871, Japan.
Sasaki T; Research Institute for Microbial Diseases and Center for Infectious Disease Education and Research, Osaka University, Suita, Osaka, 565-0871, Japan.
Suzuki K; Research Institute for Microbial Diseases and Center for Infectious Disease Education and Research, Osaka University, Suita, Osaka, 565-0871, Japan.; TANAKA Kikinzoku Kogyo K.K, Hiratsuka, Kanagawa, 254-0076, Japan.
Uno K; Division of Basic Research, Louis Pasteur Center for Medical Research, Kyoto, 606-8225, Japan.
Shimizu J; MiCAN Technologies Inc., Kyoto, 615-8245, Japan.
Okamoto T; Institute for Advanced Co-Creation Studies, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, 565-0781, Japan.
Matsumoto H; Trauma and Acute Critical Care Center, Osaka University, Suita, Osaka, 565-0871, Japan.
Matsuura H; Osaka Prefectural Nakakawachi Emergency and Critical Care Center, Higashiosaka, Osaka, 678-0947, Japan.
Hashimoto S; Osaka Prefectural Hospital Organization Osaka Habikino Medical Center, Habikino, Osaka, 583-8588, Japan.
Tanaka T; Osaka Prefectural Hospital Organization Osaka Habikino Medical Center, Habikino, Osaka, 583-8588, Japan.
Harada H; Yao Tokushukai General Hospital, Yao, Osaka, 581-0011, Japan.
Tomita M; Kobe Tokushukai Hospital, Kobe, Hyogo, 655-0017, Japan.
Kaneko M; Suita Tokushukai Hospital, Suita, Osaka, 565-0814, Japan.
Yoshizaki K; Institute of Scientific and Industry Research, Osaka University, Ibaraki, Osaka, 567-0047, Japan.
Shioda T; Research Institute for Microbial Diseases and Center for Infectious Disease Education and Research, Osaka University, Suita, Osaka, 565-0871, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 May 16; Vol. 12 (1), pp. 8108. Date of Electronic Publication: 2022 May 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibodies, Viral*/metabolism
COVID-19*
Coronavirus Nucleocapsid Proteins*/immunology
Interleukin-6*/metabolism
SARS-CoV-2*/immunology
SARS-CoV-2*/metabolism
Cytokine Release Syndrome/etiology ; Cytokine Release Syndrome/metabolism ; Cytokines ; Humans ; Phosphoproteins/immunology

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Skocz do pozycji: 6.

Tytuł:: Cross-Recognition of SARS-CoV-2 B-Cell Epitopes with Other Betacoronavirus Nucleoproteins.
Autorzy:: Tajuelo A; Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.
López-Siles M; Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.
Más V; Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.
Pérez-Romero P; Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.
Aguado JM; Hospital Universitario '12 de Octubre', 28041 Madrid, Spain.
Briz V; Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.
McConnell MJ; Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.
Martín-Galiano AJ; Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.
López D; Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 10; Vol. 23 (6). Date of Electronic Publication: 2022 Mar 10.
Typ publikacji:: Journal Article
MeSH Terms:: Coronavirus Nucleocapsid Proteins/*immunology
Coronavirus OC43, Human/*immunology
Cross Reactions/*immunology
Epitope Mapping/*methods
Epitopes, B-Lymphocyte/*immunology
SARS-CoV-2/*immunology
Adult ; Amino Acid Sequence ; COVID-19/immunology ; COVID-19/virology ; Cohort Studies ; Coronavirus Nucleocapsid Proteins/chemistry ; Coronavirus Nucleocapsid Proteins/genetics ; Coronavirus OC43, Human/genetics ; Coronavirus OC43, Human/physiology ; Cross Reactions/genetics ; Enzyme-Linked Immunosorbent Assay/methods ; Epitopes, B-Lymphocyte/metabolism ; HEK293 Cells ; Health Personnel/statistics & numerical data ; Humans ; Protein Domains ; SARS-CoV-2/genetics ; SARS-CoV-2/physiology ; Sequence Homology, Amino Acid ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology

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Skocz do pozycji: 7.

Tytuł:: Loss of Detection of sgN Precedes Viral Abridged Replication in COVID-19-Affected Patients-A Target for SARS-CoV-2 Propagation.
Autorzy:: Ferrucci V; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, 80131 Naples, Italy.
de Antonellis P; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, 80131 Naples, Italy.
Quarantelli F; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, 80131 Naples, Italy.
Asadzadeh F; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, 80131 Naples, Italy.
Bibbò F; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, 80131 Naples, Italy.
Siciliano R; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.
Sorice C; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, 80131 Naples, Italy.
Pisano I; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.
Izzo B; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, 80131 Naples, Italy.
Di Domenico C; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.
Boccia A; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.
Vargas M; Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80131 Naples, Italy.
Pierri B; Istituto Zooprofilattico Sperimentale del Mezzogiorno, 80055 Naples, Italy.
Viscardi M; Istituto Zooprofilattico Sperimentale del Mezzogiorno, 80055 Naples, Italy.
Brandi S; Istituto Zooprofilattico Sperimentale del Mezzogiorno, 80055 Naples, Italy.
Fusco G; Istituto Zooprofilattico Sperimentale del Mezzogiorno, 80055 Naples, Italy.
Cerino P; Istituto Zooprofilattico Sperimentale del Mezzogiorno, 80055 Naples, Italy.
De Pietro L; U.O.C. Pneumologia, Ospedale Boscotrecase-Asl Napoli3 Sud, 80042 Naples, Italy.
Furfaro C; Dipartimento di Medicina di Laboratorio e Anatomia Patologica, Nola Hospital, Asl Napoli 3 Sud, 80035 Naples, Italy.
Napolitano LA; Dipartimento di Medicina di Laboratorio e Anatomia Patologica, Nola Hospital, Asl Napoli 3 Sud, 80035 Naples, Italy.
Paolella G; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, 80131 Naples, Italy.
Festa L; Unità Speciale di Continuità Assistenziale (USCA), Asl Benevento, 82100 Benevento, Italy.; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, 80131 Naples, Italy.
Marzinotto S; Dipartimento di Medicina di Laboratorio, Università degli Studi di Udine, 33100 Udine, Italy.
Conte MC; Unità Speciale di Continuità Assistenziale (USCA), Asl Benevento, 82100 Benevento, Italy.
Gentile I; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, 80131 Naples, Italy.
Servillo G; Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80131 Naples, Italy.
Curcio F; Dipartimento di Medicina di Laboratorio, Università degli Studi di Udine, 33100 Udine, Italy.
de Cristofaro T; IEOS-Institute of Experimental Endocrinology and Oncology G. Salvatore, National Research Council, 80131 Naples, Italy.; BioMol Laboratories srl, 80146 Naples, Italy.
Broccolo F; Laboratory of Molecular Microbiology and Virology, School of Medicine, University of Milano-Bicocca, 20900 Monza, Italy.
Capoluongo E; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, 80131 Naples, Italy.; DAI Medicina di Laboratorio e Trasfusionale, University of Naples Federico II, 80131 Naples, Italy.
Zollo M; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, 80131 Naples, Italy.; DAI Medicina di Laboratorio e Trasfusionale, University of Naples Federico II, 80131 Naples, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Feb 09; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 09.
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19/*virology
Coronavirus Nucleocapsid Proteins/*genetics
SARS-CoV-2/*physiology
Virus Replication/*physiology
Coronavirus Nucleocapsid Proteins/analysis ; Giant Cells/drug effects ; Giant Cells/virology ; HEK293 Cells ; Humans ; Limit of Detection ; Nasopharynx/virology ; Phosphoproteins/analysis ; Phosphoproteins/genetics ; RNA, Antisense/pharmacology ; RNA, Viral ; Ribonuclease P/genetics ; SARS-CoV-2/drug effects ; SARS-CoV-2/genetics ; Sensitivity and Specificity ; Social Isolation ; Viral Load ; Viroporin Proteins/genetics ; Virus Replication/drug effects

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Skocz do pozycji: 8.

Tytuł:: Escherichia coli recombinant expression of SARS-CoV-2 protein fragments.
Autorzy:: McGuire BE; Department of Biochemistry and Microbiology, University of Victoria, STN CSC, PO Box 1700, Victoria, BC, V8W 2Y2, Canada.
Mela JE; Department of Biochemistry and Microbiology, University of Victoria, STN CSC, PO Box 1700, Victoria, BC, V8W 2Y2, Canada.
Thompson VC; Department of Biochemistry and Microbiology, University of Victoria, STN CSC, PO Box 1700, Victoria, BC, V8W 2Y2, Canada.
Cucksey LR; Department of Biochemistry and Microbiology, University of Victoria, STN CSC, PO Box 1700, Victoria, BC, V8W 2Y2, Canada.
Stevens CE; Department of Biochemistry and Microbiology, University of Victoria, STN CSC, PO Box 1700, Victoria, BC, V8W 2Y2, Canada.
McWhinnie RL; Department of Biochemistry and Microbiology, University of Victoria, STN CSC, PO Box 1700, Victoria, BC, V8W 2Y2, Canada.
Winkler DFH; Kinexus Bioinformatics Corporation, Vancouver, BC, Canada.
Pelech S; Kinexus Bioinformatics Corporation, Vancouver, BC, Canada.; Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Nano FE; Department of Biochemistry and Microbiology, University of Victoria, STN CSC, PO Box 1700, Victoria, BC, V8W 2Y2, Canada. .; Pokaż więcej
Źródło:: Microbial cell factories [Microb Cell Fact] 2022 Feb 05; Vol. 21 (1), pp. 21. Date of Electronic Publication: 2022 Feb 05.
Typ publikacji:: Journal Article
MeSH Terms:: Coronavirus Nucleocapsid Proteins/*genetics
Escherichia coli/*metabolism
Recombinant Fusion Proteins/*biosynthesis
SARS-CoV-2/*metabolism
Spike Glycoprotein, Coronavirus/*genetics
Antibodies, Viral/immunology ; Antigen-Antibody Reactions ; COVID-19/pathology ; COVID-19/virology ; Chromatography, High Pressure Liquid ; Coronavirus Nucleocapsid Proteins/metabolism ; Humans ; Mass Spectrometry ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; Receptors, Cell Surface/genetics ; Recombinant Fusion Proteins/analysis ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/immunology ; SARS-CoV-2/isolation & purification ; Spike Glycoprotein, Coronavirus/metabolism

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Skocz do pozycji: 9.

Tytuł:: High level SARS-CoV-2 nucleocapsid refolding using mild condition for inclusion bodies solubilization: Application of high pressure at pH 9.0.
Autorzy:: Chura-Chambi RM; Centro de Biotecnologia, Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, São Paulo, SP, Brazil.
Prieto-da-Silva ARB; Laboratório de Genética, Instituto Butantan, São Paulo, SP, Brazil.
Di Lela MM; Centro de Biotecnologia, Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, São Paulo, SP, Brazil.
Oliveira JE; Centro de Biotecnologia, Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, São Paulo, SP, Brazil.
Abreu PEA; Laboratório de Bacteriologia, Instituto Butantan, São Paulo, SP, Brazil.
Meireles LR; Laboratório de Protozoologia, Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo,SP, Brazil.
de Andrade Junior HF; Laboratório de Protozoologia, Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo,SP, Brazil.
Morganti L; Centro de Biotecnologia, Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, São Paulo, SP, Brazil.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Feb 03; Vol. 17 (2), pp. e0262591. Date of Electronic Publication: 2022 Feb 03 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Protein Refolding*
Antibodies, Viral/*blood
Antigens, Viral/*chemistry
COVID-19/*blood
COVID-19/*diagnosis
Coronavirus Nucleocapsid Proteins/*chemistry
Immunoglobulin G/*blood
Inclusion Bodies/*chemistry
SARS-CoV-2/*immunology
Antibodies, Viral/immunology ; Antigens, Viral/immunology ; COVID-19/virology ; Coronavirus Nucleocapsid Proteins/immunology ; Enzyme-Linked Immunosorbent Assay/methods ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Humans ; Hydrogen-Ion Concentration ; Hydrostatic Pressure ; Immunoglobulin G/immunology ; Phosphoproteins/chemistry ; Phosphoproteins/immunology ; Protein Structure, Tertiary ; Recombinant Proteins/chemistry ; Recombinant Proteins/immunology ; Solubility

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Skocz do pozycji: 10.

Tytuł:: Hypersensitivity may be involved in severe COVID-19.
Autorzy:: Tan C; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Zheng X; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Sun F; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
He J; Department of Pathology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Shi H; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Chen M; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Tu C; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Huang Y; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Wang Z; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Liang Y; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Wu J; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Liu Y; Department of Pathology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Liu J; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Huang J; Department of Pulmonary and Critical Care Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.; Pokaż więcej
Źródło:: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2022 Feb; Vol. 52 (2), pp. 324-333. Date of Electronic Publication: 2021 Oct 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bronchi/*immunology
COVID-19/*immunology
Coronavirus Nucleocapsid Proteins/*immunology
Duodenum/*immunology
Hypersensitivity/*immunology
Immunoglobulin E/*immunology
Mast Cells/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Bronchi/metabolism ; Bronchi/pathology ; COVID-19/metabolism ; COVID-19/pathology ; COVID-19/physiopathology ; Case-Control Studies ; Coronavirus Nucleocapsid Proteins/metabolism ; Duodenum/metabolism ; Duodenum/pathology ; Female ; Humans ; Hypersensitivity/metabolism ; Hypersensitivity/pathology ; Hypersensitivity/physiopathology ; Lung/physiopathology ; Male ; Mast Cells/metabolism ; Mast Cells/pathology ; Middle Aged ; Mucous Membrane/immunology ; Mucous Membrane/metabolism ; Mucous Membrane/pathology ; Phosphoproteins/immunology ; Phosphoproteins/metabolism ; Recovery of Function ; Respiratory Hypersensitivity/physiopathology ; Retrospective Studies ; SARS-CoV-2 ; Severity of Illness Index ; Spike Glycoprotein, Coronavirus/metabolism ; Young Adult

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Skocz do pozycji: 11.

Tytuł:: Ultrasensitive detection of SARS-CoV-2 nucleocapsid protein using large gold nanoparticle-enhanced surface plasmon resonance.
Autorzy:: Yano TA; Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, 770-8506, Japan. .
Kajisa T; Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, 770-8506, Japan.; Graduate School of Interdisciplinary New Science, Toyo University, 2100, Kujirai, Kawagoe, Saitama, 350-8585, Japan.
Ono M; JVCKENWOOD Corporation, 58-7, Shinmei-cho, Yokosuka, Kanagawa, 239-8550, Japan.
Miyasaka Y; JVCKENWOOD Corporation, 58-7, Shinmei-cho, Yokosuka, Kanagawa, 239-8550, Japan.
Hasegawa Y; JVCKENWOOD Corporation, 58-7, Shinmei-cho, Yokosuka, Kanagawa, 239-8550, Japan.
Saito A; JVCKENWOOD Corporation, 58-7, Shinmei-cho, Yokosuka, Kanagawa, 239-8550, Japan.
Otsuka K; Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, 770-8506, Japan.; Department of Immunology and Parasitology, Graduate School of Medical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, 770-8503, Japan.
Sakane A; Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, 770-8506, Japan.; Department of Biochemistry, Graduate School of Medical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, 770-8503, Japan.
Sasaki T; Department of Biochemistry, Graduate School of Medical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, 770-8503, Japan.
Yasutomo K; Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, 770-8506, Japan.; Department of Immunology and Parasitology, Graduate School of Medical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, 770-8503, Japan.
Hamajima R; Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.; Laboratory of Sericulture and Entomoresources, Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Nagoya, 464-8601, Japan.
Kanai Y; Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Kobayashi T; Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Matsuura Y; Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.; Center for Infectious Diseases Education and Research, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Itonaga M; JVCKENWOOD Corporation, 58-7, Shinmei-cho, Yokosuka, Kanagawa, 239-8550, Japan.
Yasui T; Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, 770-8506, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jan 20; Vol. 12 (1), pp. 1060. Date of Electronic Publication: 2022 Jan 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Coronavirus Nucleocapsid Proteins*/analysis
Coronavirus Nucleocapsid Proteins*/chemistry
Surface Plasmon Resonance*
Gold/*chemistry
Metal Nanoparticles/*chemistry
SARS-CoV-2/*chemistry
Phosphoproteins/analysis ; Phosphoproteins/chemistry

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Skocz do pozycji: 12.

Tytuł:: Construction of SARS-CoV-2 virus-like particles in plant.
Autorzy:: Moon KB; Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.
Jeon JH; Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.
Choi H; Department of Biological Sciences, School of Life Sciences, Ulsan National Institute of Science and Technology, UNIST-Gil 50, Ulsan, 44919, Republic of Korea.
Park JS; Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.
Park SJ; Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.
Lee HJ; Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.
Park JM; Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.
Cho HS; Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.
Moon JS; Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.
Oh H; Core Facility Management Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.
Kang S; Department of Biological Sciences, School of Life Sciences, Ulsan National Institute of Science and Technology, UNIST-Gil 50, Ulsan, 44919, Republic of Korea.
Mason HS; Center for Immunotherapy, Vaccines, and Virotherapy (CIVV), The Biodesign Institute at ASU, Tempe, AZ, 85287, USA.
Kwon SY; Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea. .
Kim HS; Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jan 19; Vol. 12 (1), pp. 1005. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: COVID-19/*immunology
COVID-19 Vaccines/*immunology
Coronavirus M Proteins/*immunology
Coronavirus Nucleocapsid Proteins/*immunology
SARS-CoV-2/*immunology
Vaccines, Virus-Like Particle/*immunology
Viroporin Proteins/*immunology
COVID-19/prevention & control ; COVID-19/virology ; COVID-19 Vaccines/administration & dosage ; Coronavirus M Proteins/genetics ; Coronavirus M Proteins/metabolism ; Coronavirus Nucleocapsid Proteins/genetics ; Coronavirus Nucleocapsid Proteins/metabolism ; Humans ; Nicotiana/immunology ; Nicotiana/metabolism ; Nicotiana/virology ; Vaccines, Virus-Like Particle/genetics ; Vaccines, Virus-Like Particle/metabolism ; Viroporin Proteins/genetics ; Viroporin Proteins/metabolism

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Skocz do pozycji: 13.

Tytuł:: SARS-CoV-2 variants with reduced infectivity and varied sensitivity to the BNT162b2 vaccine are developed during the course of infection.
Autorzy:: Khateeb D; Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Gabrieli T; Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Sofer B; Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Hattar A; Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Cordela S; Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Chaouat A; The Concern Foundation Laboratories at the Lautenberg Center for Immunology and Cancer Research, Institute for Medical Research Israel Canada (IMRIC), The Hebrew University Hadassah Medical School, Jerusalem, Israel.
Spivak I; Department of Pediatrics B, Ruth Rappaport Children's Hospital, Rambam Health Care Campus, Haifa, Israel.
Lejbkowicz I; Epidemiology Unit and Biobank, Rambam Health Care Campus, Haifa, Israel.
Almog R; Epidemiology Unit and Biobank, Rambam Health Care Campus, Haifa, Israel.
Mandelboim M; Central Virology Laboratory, Sheba Medical Center, Tel Hashomer, Israel.
Bar-On Y; Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2022 Jan 12; Vol. 18 (1), pp. e1010242. Date of Electronic Publication: 2022 Jan 12 (Print Publication: 2022).
Typ publikacji:: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: COVID-19*/genetics
COVID-19*/immunology
COVID-19*/prevention & control
Coronavirus Nucleocapsid Proteins*/genetics
Coronavirus Nucleocapsid Proteins*/immunology
Databases, Nucleic Acid*
Genome, Viral*
Mutation*
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
Spike Glycoprotein, Coronavirus*/genetics
Spike Glycoprotein, Coronavirus*/immunology
BNT162 Vaccine/*administration & dosage
Adult ; Aged ; Child ; Female ; HEK293 Cells ; Humans ; Male ; Middle Aged ; Phosphoproteins/genetics ; Phosphoproteins/immunology ; Sequence Analysis, RNA
SCR Organism:: SARS-CoV-2 variants

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Skocz do pozycji: 14.

Tytuł:: Development of a quantitative COVID-19 multiplex assay and its use for serological surveillance in a low SARS-CoV-2 incidence community.
Autorzy:: Guarino C; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America.
Larson E; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America.
Babasyan S; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America.
Rollins A; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America.
Joshi LR; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America.
Laverack M; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America.
Parrilla L; Cayuga Medical Center, Ithaca, NY, United States of America.
Plocharczyk E; Cayuga Medical Center, Ithaca, NY, United States of America.
Diel DG; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America.
Wagner B; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jan 21; Vol. 17 (1), pp. e0262868. Date of Electronic Publication: 2022 Jan 21 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibodies, Viral/*chemistry
COVID-19/*diagnosis
COVID-19 Serological Testing/*methods
Coronavirus Nucleocapsid Proteins/*immunology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Neutralizing/chemistry ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; COVID-19/blood ; COVID-19/epidemiology ; COVID-19 Serological Testing/standards ; Coronavirus Nucleocapsid Proteins/chemistry ; Epidemiological Monitoring ; Female ; Humans ; Immunoglobulin A/chemistry ; Immunoglobulin A/immunology ; Immunoglobulin G/chemistry ; Immunoglobulin G/immunology ; Immunoglobulin M/chemistry ; Immunoglobulin M/immunology ; Male ; Middle Aged ; New York/epidemiology ; Phosphoproteins/chemistry ; Phosphoproteins/immunology ; Protein Interaction Domains and Motifs ; Recombinant Proteins/chemistry ; Recombinant Proteins/immunology ; SARS-CoV-2/classification ; Sensitivity and Specificity ; Spike Glycoprotein, Coronavirus/chemistry

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Skocz do pozycji: 15.

Tytuł:: Rapid assessment of SARS-CoV-2-evolved variants using virus-like particles.
Autorzy:: Syed AM; Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.
Taha TY; Gladstone Institute of Virology, San Francisco, CA, USA.
Tabata T; Gladstone Institute of Virology, San Francisco, CA, USA.
Chen IP; Gladstone Institute of Virology, San Francisco, CA, USA.; Biomedical Sciences Graduate Program, University of California, San Francisco, CA, USA.
Ciling A; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.
Khalid MM; Gladstone Institute of Virology, San Francisco, CA, USA.
Sreekumar B; Gladstone Institute of Virology, San Francisco, CA, USA.
Chen PY; Gladstone Institute of Virology, San Francisco, CA, USA.
Hayashi JM; Gladstone Institute of Virology, San Francisco, CA, USA.
Soczek KM; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.
Ott M; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Gladstone Institute of Virology, San Francisco, CA, USA.; Department of Medicine, University of California San Francisco, CA, USA.
Doudna JA; Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2021 Dec 24; Vol. 374 (6575), pp. 1626-1632. Date of Electronic Publication: 2021 Nov 04.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Artificial Virus-Like Particles*
Mutation*
Coronavirus Nucleocapsid Proteins/*genetics
SARS-CoV-2/*genetics
SARS-CoV-2/*physiology
Animals ; Cell Line ; Coronavirus Envelope Proteins/genetics ; Coronavirus Envelope Proteins/metabolism ; Coronavirus Nucleocapsid Proteins/metabolism ; Evolution, Molecular ; Genome, Viral ; Humans ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; Plasmids ; RNA, Messenger/genetics ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism ; Viral Genome Packaging ; Viral Matrix Proteins/genetics ; Viral Matrix Proteins/metabolism ; Virus Internalization
SCR Organism:: SARS-CoV-2 variants

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Skocz do pozycji: 16.

Tytuł:: Human CD4 T cells specific for dominant epitopes of SARS-CoV-2 Spike and Nucleocapsid proteins with therapeutic potential.
Autorzy:: Verhagen J; Department of Medicine 5, Haematology and Oncology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
van der Meijden ED; Department of Medicine 5, Haematology and Oncology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Lang V; Department of Medicine 5, Haematology and Oncology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Kremer AE; Department of Medicine 1, Gastroenterology, Pneumology and Endocrinology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Völkl S; Department of Medicine 5, Haematology and Oncology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Mackensen A; Department of Medicine 5, Haematology and Oncology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Aigner M; Department of Medicine 5, Haematology and Oncology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Kremer AN; Department of Medicine 5, Haematology and Oncology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.; Pokaż więcej
Źródło:: Clinical and experimental immunology [Clin Exp Immunol] 2021 Sep; Vol. 205 (3), pp. 363-378. Date of Electronic Publication: 2021 Jun 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CD4-Positive T-Lymphocytes/*immunology
CD4-Positive T-Lymphocytes/*virology
COVID-19/*immunology
COVID-19/*therapy
Coronavirus Nucleocapsid Proteins/*immunology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Adult ; Aged ; Aged, 80 and over ; Amino Acid Sequence ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/virology ; COVID-19/virology ; Clone Cells/immunology ; Clone Cells/virology ; Coronavirus Nucleocapsid Proteins/chemistry ; Coronavirus Nucleocapsid Proteins/genetics ; Cytokines/biosynthesis ; Epitopes, T-Lymphocyte/chemistry ; Epitopes, T-Lymphocyte/genetics ; Epitopes, T-Lymphocyte/immunology ; Female ; Humans ; Immunization, Passive ; Immunodominant Epitopes/chemistry ; Immunodominant Epitopes/genetics ; Immunodominant Epitopes/immunology ; Male ; Middle Aged ; Phosphoproteins/chemistry ; Phosphoproteins/genetics ; Phosphoproteins/immunology ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/immunology ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; COVID-19 Serotherapy

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Skocz do pozycji: 17.

Tytuł:: Phosphorylation of SARS-CoV-2 Orf9b Regulates Its Targeting to Two Binding Sites in TOM70 and Recruitment of Hsp90.
Autorzy:: Brandherm L; Institute for Biochemistry and Pathobiochemistry, Ruhr-University Bochum, 44801 Bochum, Germany.
Kobaš AM; Institute for Biochemistry and Pathobiochemistry, Ruhr-University Bochum, 44801 Bochum, Germany.
Klöhn M; Department of Molecular & Medical Virology, Ruhr-University Bochum, 44801 Bochum, Germany.
Brüggemann Y; Department of Molecular & Medical Virology, Ruhr-University Bochum, 44801 Bochum, Germany.
Pfaender S; Department of Molecular & Medical Virology, Ruhr-University Bochum, 44801 Bochum, Germany.
Rassow J; Institute for Biochemistry and Pathobiochemistry, Ruhr-University Bochum, 44801 Bochum, Germany.
Kreimendahl S; Institute for Biochemistry and Pathobiochemistry, Ruhr-University Bochum, 44801 Bochum, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 26; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 26.
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19/*transmission
Coronavirus Nucleocapsid Proteins/*metabolism
HSP90 Heat-Shock Proteins/*metabolism
Mitochondrial Membrane Transport Proteins/*metabolism
SARS-CoV-2/*pathogenicity
Animals ; Binding Sites/genetics ; COVID-19/immunology ; COVID-19/virology ; Chlorocebus aethiops ; Coronavirus Nucleocapsid Proteins/genetics ; Coronavirus Nucleocapsid Proteins/immunology ; Coronavirus Nucleocapsid Proteins/isolation & purification ; Humans ; Interferon Type I/immunology ; Interferon Type I/metabolism ; Mitochondrial Membrane Transport Proteins/genetics ; Mitochondrial Membrane Transport Proteins/isolation & purification ; Mitochondrial Precursor Protein Import Complex Proteins ; Mutation ; Phosphoproteins/genetics ; Phosphoproteins/immunology ; Phosphoproteins/isolation & purification ; Phosphoproteins/metabolism ; Phosphorylation ; Protein Binding/genetics ; Protein Binding/immunology ; Protein Domains/genetics ; Recombinant Proteins/genetics ; Recombinant Proteins/immunology ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; Vero Cells

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Tytuł:: Immune response dynamics in COVID-19 patients to SARS-CoV-2 and other human coronaviruses.
Autorzy:: Ravindran R; Department of Pathology and Laboratory Medicine, University of California, Davis, CA, United States of America.
McReynolds C; Department of Entomology and Nematology, University of California, Davis, CA, United States of America.
Yang J; Department of Entomology and Nematology, University of California, Davis, CA, United States of America.
Hammock BD; Department of Entomology and Nematology, University of California, Davis, CA, United States of America.
Ikram A; National Institutes of Health, Rawalpindi, Pakistan.
Ali A; National Institutes of Health, Rawalpindi, Pakistan.
Bashir A; National Institutes of Health, Rawalpindi, Pakistan.
Zohra T; National Institutes of Health, Rawalpindi, Pakistan.
Chang WLW; California National Primate Research Center, University of California, Davis, CA, United States of America.; Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA, United States of America.
Hartigan-O'Connor DJ; California National Primate Research Center, University of California, Davis, CA, United States of America.
Rashidi HH; Department of Pathology and Laboratory Medicine, University of California, Davis, CA, United States of America.
Khan IH; Department of Pathology and Laboratory Medicine, University of California, Davis, CA, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Jul 09; Vol. 16 (7), pp. e0254367. Date of Electronic Publication: 2021 Jul 09 (Print Publication: 2021).
Typ publikacji:: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibodies, Viral*/blood
Antibodies, Viral*/immunology
COVID-19*/blood
COVID-19*/immunology
Chemokines*/blood
Chemokines*/immunology
Coronavirus Nucleocapsid Proteins*/blood
Coronavirus Nucleocapsid Proteins*/immunology
Immunoglobulin G*/blood
Immunoglobulin G*/immunology
Immunoglobulin M*/blood
Immunoglobulin M*/immunology
SARS-CoV-2*/immunology
SARS-CoV-2*/metabolism
Spike Glycoprotein, Coronavirus*/blood
Spike Glycoprotein, Coronavirus*/immunology
Adult ; Animals ; Female ; Humans ; Macaca mulatta ; Male ; Middle Aged ; Phosphoproteins/blood ; Phosphoproteins/immunology ; Rabbits

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Skocz do pozycji: 19.

Tytuł:: Development and characterization of two equine formulations towards SARS-CoV-2 proteins for the potential treatment of COVID-19.
Autorzy:: León G; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Herrera M; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Vargas M; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica. .
Arguedas M; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Sánchez A; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Segura Á; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Gómez A; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Solano G; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Corrales-Aguilar E; Virology-CIET (Research Center for Tropical Diseases), Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.
Risner K; National Center for Biodefense and Infectious Diseases, George Mason University, Virginia, USA.
Narayanan A; National Center for Biodefense and Infectious Diseases, George Mason University, Virginia, USA.
Bailey C; National Center for Biodefense and Infectious Diseases, George Mason University, Virginia, USA.
Villalta M; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Hernández A; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Sánchez A; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Cordero D; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Solano D; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Durán G; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Segura E; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Cerdas M; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Umaña D; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Moscoso E; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Estrada R; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Gutiérrez J; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Méndez M; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Castillo AC; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Sánchez L; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Sánchez R; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Gutiérrez JM; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Díaz C; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.
Alape A; Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, Costa Rica.; Departamento de Bioquímica, Escuela de Medicina, Universidad de Costa Rica, San José, Costa Rica.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 May 10; Vol. 11 (1), pp. 9825. Date of Electronic Publication: 2021 May 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: COVID-19/*immunology
COVID-19/*therapy
Coronavirus Nucleocapsid Proteins/*immunology
Horses/*immunology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; COVID-19/virology ; Coronavirus Nucleocapsid Proteins/genetics ; Coronavirus Nucleocapsid Proteins/metabolism ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunization/methods ; Immunization, Passive/methods ; Immunoglobulin G/immunology ; Recombinant Proteins/immunology ; Recombinant Proteins/metabolism ; SARS-CoV-2/metabolism ; SARS-CoV-2/physiology ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism ; COVID-19 Serotherapy

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Tytuł:: Accurate detection and quantification of SARS-CoV-2 genomic and subgenomic mRNAs by ddPCR and meta-transcriptomics analysis.
Autorzy:: Oranger A; Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari Aldo Moro, Via Orabona 4, 70126, Bari, Italy.
Manzari C; Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari Aldo Moro, Via Orabona 4, 70126, Bari, Italy.
Chiara M; Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, National Research Council, Via Amendola 122/O, 70126, Bari, Italy.; Department of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
Notario E; Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari Aldo Moro, Via Orabona 4, 70126, Bari, Italy.
Fosso B; Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, National Research Council, Via Amendola 122/O, 70126, Bari, Italy.
Parisi A; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, 70017, Putignano (Bari), Italy.
Bianco A; Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, 70017, Putignano (Bari), Italy.
Iacobellis M; Servizio Centralizzato Aziendale di Citopatologia e Screening- PO 'Di Venere' - ASL, 70131, Bari, Italy.
d'Avenia M; Servizio Centralizzato Aziendale di Citopatologia e Screening- PO 'Di Venere' - ASL, 70131, Bari, Italy.
D'Erchia AM; Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari Aldo Moro, Via Orabona 4, 70126, Bari, Italy. .; Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, National Research Council, Via Amendola 122/O, 70126, Bari, Italy. .; Consorzio Interuniversitario Biotecnologie, 34100, Trieste, Italy. .
Pesole G; Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari Aldo Moro, Via Orabona 4, 70126, Bari, Italy. .; Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, National Research Council, Via Amendola 122/O, 70126, Bari, Italy. .; Consorzio Interuniversitario Biotecnologie, 34100, Trieste, Italy. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2021 Oct 22; Vol. 4 (1), pp. 1215. Date of Electronic Publication: 2021 Oct 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Coronavirus Nucleocapsid Proteins*
SARS-CoV-2*
Spike Glycoprotein, Coronavirus*
Transcriptome*
COVID-19/*genetics
COVID-19/*metabolism
COVID-19 Nucleic Acid Testing/*methods
Polymerase Chain Reaction/*methods
RNA, Viral/*metabolism
Computational Biology ; Humans ; Limit of Detection ; Open Reading Frames ; Phosphoproteins ; RNA, Messenger/metabolism ; Real-Time Polymerase Chain Reaction ; Reproducibility of Results

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