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Wyszukujesz frazę ""Cricetulus"" wg kryterium: Temat


Tytuł :
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Autorzy :
Kong XT; College of Life Sciences, Qufu Normal University, 273165 Qufu, Shandong, China. Electronic address: .
Wang Z; College of Life Sciences, Qufu Normal University, 273165 Qufu, Shandong, China. Electronic address: .
Mou JJ; College of Life Sciences, Qufu Normal University, 273165 Qufu, Shandong, China. Electronic address: .
Li CS; College of Life Sciences, Qufu Normal University, 273165 Qufu, Shandong, China. Electronic address: .
Xue HL; College of Life Sciences, Qufu Normal University, 273165 Qufu, Shandong, China. Electronic address: .
Wu M; College of Life Sciences, Qufu Normal University, 273165 Qufu, Shandong, China. Electronic address: .
Chen L; College of Life Sciences, Qufu Normal University, 273165 Qufu, Shandong, China. Electronic address: .
Xu JH; College of Life Sciences, Qufu Normal University, 273165 Qufu, Shandong, China. Electronic address: .
Xu LX; College of Life Sciences, Qufu Normal University, 273165 Qufu, Shandong, China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Apr-May; Vol. 253, pp. 110547. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Autophagy*
Aging/*metabolism
Cricetulus/*metabolism
Harderian Gland/*cytology
Mitochondria/*metabolism
Animals ; Caspase 3/metabolism ; Cricetulus/genetics ; Cricetulus/growth & development ; Cricetulus/physiology ; DNA Fragmentation ; Female ; Gene Expression Regulation, Developmental ; Male
Czasopismo naukowe
Tytuł :
Functional effects of berberine in modulating mitochondrial dysfunction and inflammatory response in the respective amyloidogenic cells and activated microglial cells - In vitro models simulating Alzheimer's disease pathology.
Autorzy :
Wong LR; Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117559, Republic of Singapore.
Tan EA; Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117559, Republic of Singapore.
Lim MEJ; Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117559, Republic of Singapore.
Shen W; Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117559, Republic of Singapore.
Lian XL; Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117559, Republic of Singapore.
Wang Y; Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117559, Republic of Singapore.
Chen L; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, 611137 Chengdu, Sichuan, People's Republic of China. Electronic address: .
Ho PC; Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117559, Republic of Singapore. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Oct 01; Vol. 282, pp. 119824. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Alzheimer Disease/*drug therapy
Amyloid beta-Peptides/*metabolism
Berberine/*pharmacology
Microglia/*metabolism
Mitochondria/*metabolism
Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Animals ; CHO Cells ; Cricetulus ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/pathology ; Mice ; Microglia/pathology ; Mitochondria/pathology
Czasopismo naukowe
Tytuł :
Evaluating a new mixed-mode resin Diamond MMC Mustang using Capto MMC ImpRes as a benchmark.
Autorzy :
Zhang S; Technology and Process Development (TPD), WuXi Biologics, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, China.
Wan Y; Technology and Process Development (TPD), WuXi Biologics, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, China.
Duan J; Technology and Process Development (TPD), WuXi Biologics, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, China.
Li Y; Technology and Process Development (TPD), WuXi Biologics, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, China. Electronic address: .
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Źródło :
Protein expression and purification [Protein Expr Purif] 2021 Oct; Vol. 186, pp. 105930. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Antibodies, Bispecific/*isolation & purification
Chromatography, Affinity/*methods
Animals ; Antibodies, Bispecific/immunology ; Benchmarking ; CHO Cells ; Chromatography, Affinity/instrumentation ; Cricetulus ; Staphylococcal Protein A/analysis ; Staphylococcal Protein A/immunology
Czasopismo naukowe
Tytuł :
Activity of the mouse Notch ligand DLL1 is sensitive to C-terminal tagging in vivo.
Autorzy :
Schuster-Gossler K; Institute for Molecular Biology, OE5250, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Boldt K; Institute of Ophthalmic Research, Center for Ophthalmology, University of Tübingen, Elfriede-Aulhorn-Strasse 7, 72076, Tübingen, Germany.
Bornhorst D; Institute for Molecular Biology, OE5250, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.; Institute of Biochemistry and Biology, Potsdam University, 14476, Potsdam, Germany.; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, USA.
Delany-Heiken P; Institute for Molecular Biology, OE5250, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Ueffing M; Institute of Ophthalmic Research, Center for Ophthalmology, University of Tübingen, Elfriede-Aulhorn-Strasse 7, 72076, Tübingen, Germany.
Gossler A; Institute for Molecular Biology, OE5250, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. .
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Źródło :
BMC research notes [BMC Res Notes] 2021 Sep 28; Vol. 14 (1), pp. 383. Date of Electronic Publication: 2021 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Embryo, Mammalian*
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Ligands ; Mice ; Protein Transport
Czasopismo naukowe
Tytuł :
Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Autorzy :
Li T; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Xue W; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Zheng Q; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Song S; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, 518112, Shenzhen, Guangdong, China.; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, 518112, Shenzhen, Guangdong, China.
Yang C; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Xiong H; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Zhang S; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Hong M; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Zhang Y; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Yu H; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Zhang Y; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Sun H; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Huang Y; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Deng T; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Chi X; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Li J; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Wang S; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Zhou L; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Chen T; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Wang Y; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Cheng T; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Zhang T; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Yuan Q; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Zhao Q; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
Zhang J; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China.; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China.
McLellan JS; Department of Molecular Biosciences, The University of Texas at Austin, Austin, 78712, TX, USA.
Zhou ZH; California NanoSystems Institute (CNSI), UCLA, Los Angeles, 90095, CA, USA. .; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, 90095, CA, USA. .
Zhang Z; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, 518112, Shenzhen, Guangdong, China. .; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, 518112, Shenzhen, Guangdong, China. .
Li S; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China. .; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China. .
Gu Y; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China. .; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China. .
Xia N; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, 361102, Xiamen, Fujian, China. .; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, 361102, Xiamen, Fujian, China. .; Research Unit of Frontier Technology of Structural Vaccinology, Chinese Academy of Medical Sciences, 518112, Xiamen, Fujian, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 27; Vol. 12 (1), pp. 5652. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Viral/*immunology
Broadly Neutralizing Antibodies/*immunology
COVID-19/*therapy
Immunization, Passive/*methods
SARS-CoV-2/*immunology
Animals ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/isolation & purification ; Antibodies, Monoclonal/metabolism ; Antibodies, Viral/administration & dosage ; Antibodies, Viral/isolation & purification ; Antibodies, Viral/metabolism ; Binding Sites/genetics ; Binding Sites/immunology ; Broadly Neutralizing Antibodies/administration & dosage ; Broadly Neutralizing Antibodies/isolation & purification ; Broadly Neutralizing Antibodies/metabolism ; CHO Cells ; COVID-19/epidemiology ; COVID-19/immunology ; COVID-19/virology ; Chlorocebus aethiops ; Cricetulus ; Epitopes/immunology ; HEK293 Cells ; Humans ; Mice ; Middle East Respiratory Syndrome Coronavirus/genetics ; Middle East Respiratory Syndrome Coronavirus/immunology ; Neutralization Tests ; Pandemics/prevention & control ; Protein Multimerization ; Receptors, Virus/metabolism ; SARS-CoV-2/genetics ; Sf9 Cells ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology ; Spike Glycoprotein, Coronavirus/metabolism ; Vero Cells
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Risk analysis of leachables in cell and gene therapy using a CAR-T model process.
Autorzy :
Budde D; Sartorius Stedim Biotech GmbH, August Spindler-Str. 11, 37079 Goettingen, Germany; Universität Bielefeld, Universitätsstraße 25, 33615 Bielefeld, Germany. Electronic address: .
Jurkiewicz E; Sartorius Stedim Biotech GmbH, August Spindler-Str. 11, 37079 Goettingen, Germany.
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2021 Sep 25; Vol. 607, pp. 121015. Date of Electronic Publication: 2021 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
Receptors, Chimeric Antigen*
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Genetic Therapy ; Risk Assessment
Czasopismo naukowe
Tytuł :
A Protein-Based Biosensor for Detecting Calcium by Magnetic Resonance Imaging.
Autorzy :
Ozbakir HF
Miller ADC
Fishman KB
Martins AF
Kippin TE
Mukherjee A
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Źródło :
ACS sensors [ACS Sens] 2021 Sep 24; Vol. 6 (9), pp. 3163-3169. Date of Electronic Publication: 2021 Aug 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosensing Techniques*
Calcium*
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Magnetic Resonance Imaging
Czasopismo naukowe
Tytuł :
Enhanced Antiviral Function of Magnesium Chloride-Modified Heparin on a Broad Spectrum of Viruses.
Autorzy :
Mese K; Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Witten/Herdecke University, 58453 Witten, Germany.
Bunz O; Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Witten/Herdecke University, 58453 Witten, Germany.; Department of Prosthodontics, School of Dentistry, Faculty of Health, Witten/Herdecke University, 58455 Witten, Germany.
Volkwein W; Bavarian Health and Food Safety Authority (LGL), 85764 Oberschleissheim, Germany.
Vemulapalli SPB; Department of NMR-Based Structural Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Zhang W; Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Witten/Herdecke University, 58453 Witten, Germany.
Schellhorn S; Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Witten/Herdecke University, 58453 Witten, Germany.
Heenemann K; Center for Infectious Diseases, Institute of Virology, Faculty of Veterinary Medicine, University of Leipzig, 04103 Leipzig, Germany.
Rueckner A; Center for Infectious Diseases, Institute of Virology, Faculty of Veterinary Medicine, University of Leipzig, 04103 Leipzig, Germany.
Sing A; Bavarian Health and Food Safety Authority (LGL), 85764 Oberschleissheim, Germany.
Vahlenkamp TW; Center for Infectious Diseases, Institute of Virology, Faculty of Veterinary Medicine, University of Leipzig, 04103 Leipzig, Germany.
Severing AL; Centre for Biomedical Education and Research (ZBAF), Institute for Translational Wound Research, Witten/Herdecke University, 58453 Witten, Germany.
Gao J; Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Witten/Herdecke University, 58453 Witten, Germany.
Aydin M; Center for Child and Adolescent Medicine, Center for Clinical and Translational Research (CCTR), Helios University Hospital Wuppertal, Witten/Herdecke University, 42283 Wuppertal, Germany.
Jung D; Centre for Biomedical Education and Research, Institute of Pharmacology and Toxicology, Witten/Herdecke University, 58453 Witten, Germany.
Bachmann HS; Centre for Biomedical Education and Research, Institute of Pharmacology and Toxicology, Witten/Herdecke University, 58453 Witten, Germany.
Zänker KS; Center for Biomedical Education and Research (ZBAF), Institute of Immunology, Witten/Herdecke University, 58453 Witten, Germany.
Busch U; Bavarian Health and Food Safety Authority (LGL), 85764 Oberschleissheim, Germany.
Baiker A; Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Witten/Herdecke University, 58453 Witten, Germany.; Bavarian Health and Food Safety Authority (LGL), 85764 Oberschleissheim, Germany.
Griesinger C; Centre for Biomedical Education and Research, Institute of Pharmacology and Toxicology, Witten/Herdecke University, 58453 Witten, Germany.
Ehrhardt A; Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Witten/Herdecke University, 58453 Witten, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 17; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*pharmacology
Heparin/*pharmacology
Magnesium Chloride/*pharmacology
Acyclovir/pharmacology ; Adenoviruses, Human/drug effects ; Adenoviruses, Human/physiology ; Animals ; Antiviral Agents/chemistry ; CHO Cells ; Cell Line, Tumor ; Chlorocebus aethiops ; Cricetulus ; Drug Evaluation, Preclinical ; Fibroblasts ; Heparin/chemistry ; Herpesvirus 1, Human/drug effects ; Herpesvirus 1, Human/physiology ; Humans ; Magnesium Chloride/chemistry ; Magnetic Resonance Spectroscopy ; Microbial Sensitivity Tests ; Molecular Structure ; Primary Cell Culture ; SARS-CoV-2/drug effects ; SARS-CoV-2/physiology ; Structure-Activity Relationship ; Vero Cells ; Viral Load/drug effects ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
Human CYP enzyme-activated clastogenicity of 2-ethylhexyl diphenyl phosphate (a flame retardant) in mammalian cells.
Autorzy :
Chen Z; Department of Toxicology, School of Public Health, (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, 1023 S. Shatai Road, Guangzhou, 510515, China.
Xie J; Department of Toxicology, School of Public Health, (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, 1023 S. Shatai Road, Guangzhou, 510515, China.
Li Q; Department of Dietetics, Nanfang Hospital, Southern Medical University, 1838 N. Guangzhou Avenue, Guangzhou, 510515, China.
Hu K; Department of Toxicology, School of Public Health, (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, 1023 S. Shatai Road, Guangzhou, 510515, China.
Yang Z; Department of Toxicology, School of Public Health, (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, 1023 S. Shatai Road, Guangzhou, 510515, China.
Yu H; Department of Toxicology, School of Public Health, (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, 1023 S. Shatai Road, Guangzhou, 510515, China.
Liu Y; Department of Toxicology, School of Public Health, (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, 1023 S. Shatai Road, Guangzhou, 510515, China. Electronic address: .
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Źródło :
Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2021 Sep 15; Vol. 285, pp. 117527. Date of Electronic Publication: 2021 Jun 04.
Typ publikacji :
Journal Article
MeSH Terms :
Flame Retardants*/toxicity
Mutagens*
Animals ; Biphenyl Compounds ; Cell Line ; Cricetinae ; Cricetulus ; Humans ; Molecular Docking Simulation ; Phosphates
Czasopismo naukowe
Tytuł :
Cutting Edge: CD36 Mediates Phagocyte Tropism and Avirulence of Toxoplasma gondii .
Autorzy :
Zhao Y; Department of Medicine and Center for Immunity and Inflammation, New Jersey Medical School, Rutgers University, Newark, NJ; and.
Reyes J; Department of Medicine and Center for Immunity and Inflammation, New Jersey Medical School, Rutgers University, Newark, NJ; and.
Rovira-Diaz E; Department of Medicine and Center for Immunity and Inflammation, New Jersey Medical School, Rutgers University, Newark, NJ; and.
Fox BA; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Bzik DJ; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Yap GS; Department of Medicine and Center for Immunity and Inflammation, New Jersey Medical School, Rutgers University, Newark, NJ; and .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Sep 15; Vol. 207 (6), pp. 1507-1512. Date of Electronic Publication: 2021 Aug 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
CD36 Antigens/*deficiency
CD36 Antigens/*metabolism
Macrophages, Peritoneal/*immunology
Macrophages, Peritoneal/*parasitology
Toxoplasma/*metabolism
Toxoplasma/*pathogenicity
Toxoplasmosis, Animal/*immunology
Animals ; CD36 Antigens/genetics ; CHO Cells ; Cricetulus ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/immunology ; Immune Tolerance/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Protein-Serine-Threonine Kinases/metabolism ; Protozoan Proteins/metabolism ; RAW 264.7 Cells ; Toxoplasmosis, Animal/metabolism ; Toxoplasmosis, Animal/parasitology ; Virulence/genetics ; Virulence Factors/metabolism
Czasopismo naukowe
Tytuł :
Development of a suitable manufacturing process for production of a bioactive recombinant equine chorionic gonadotropin (reCG) in CHO-K1 cells.
Autorzy :
Villarraza CJ; UNL, CONICET, FBCB (School of Biochemistry and Biological Sciences), CBL (Biotechnological Center of Litoral), Cell Culture Laboratory, Ciudad Universitaria, Ruta Nacional 168 - Km 472.4 - C.C. 242, (S3000ZAA), Santa Fe, Argentina.
Antuña S; Biotecnofe S.A., PTLC, Ruta 168 Pje El Pozo, (CP3000), Santa Fe, Argentina.
Tardivo MB; Biotecnofe S.A., PTLC, Ruta 168 Pje El Pozo, (CP3000), Santa Fe, Argentina.
Rodríguez MC; UNL, CONICET, FBCB (School of Biochemistry and Biological Sciences), CBL (Biotechnological Center of Litoral), Cell Culture Laboratory, Ciudad Universitaria, Ruta Nacional 168 - Km 472.4 - C.C. 242, (S3000ZAA), Santa Fe, Argentina.
Mussio P; UNL, FBCB (School of Biochemistry and Biological Sciences), CBL (Biotechnological Center of Litoral), Biotechnological Development Laboratory, Ciudad Universitaria, Ruta Nacional 168 - Km 472.4 - C.C. 242 - (S3000ZAA), Santa Fe, Argentina.
Cattaneo L; UNL, FCV, R.P. Kreder, 2805, Esperanza, Santa Fe, Argentina.
Fontana D; UNL, CONICET, FBCB (School of Biochemistry and Biological Sciences), CBL (Biotechnological Center of Litoral), Cell Culture Laboratory, Ciudad Universitaria, Ruta Nacional 168 - Km 472.4 - C.C. 242, (S3000ZAA), Santa Fe, Argentina; Cellargen Biotech S.R.L., Antonia Godoy 6369 (S3000ZAA), Santa Fe, Argentina; Biotecnofe S.A., PTLC, Ruta 168 Pje El Pozo, (CP3000), Santa Fe, Argentina.
Díaz PU; UNL, FCV, R.P. Kreder, 2805, Esperanza, Santa Fe, Argentina; Laboratorio de Biología Celular y Molecular Aplicada, Instituto de Ciencias Veterinarias Del Litoral (ICiVet Litoral), Universidad Nacional Del Litoral (UNL) / Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Esperanza, Santa Fe, Argentina.
Ortega HH; UNL, FCV, R.P. Kreder, 2805, Esperanza, Santa Fe, Argentina; Laboratorio de Biología Celular y Molecular Aplicada, Instituto de Ciencias Veterinarias Del Litoral (ICiVet Litoral), Universidad Nacional Del Litoral (UNL) / Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Esperanza, Santa Fe, Argentina.
Tríbulo A; Instituto de Reproducción Animal Córdoba (IRAC), Paraje Pozo Del Tigre, Zona Rural Gral, Paz, (X5145), Córdoba, Argentina.
Macagno A; Instituto AP de Ciencias Básicas y Aplicadas, Universidad Nacional de Villa María (UNVM), Villa Del Rosario, (X5963), Córdoba, Argentina.
Bó GA; Instituto AP de Ciencias Básicas y Aplicadas, Universidad Nacional de Villa María (UNVM), Villa Del Rosario, (X5963), Córdoba, Argentina; Instituto de Reproducción Animal Córdoba (IRAC), Paraje Pozo Del Tigre, Zona Rural Gral, Paz, (X5145), Córdoba, Argentina.
Ceaglio N; UNL, CONICET, FBCB (School of Biochemistry and Biological Sciences), CBL (Biotechnological Center of Litoral), Cell Culture Laboratory, Ciudad Universitaria, Ruta Nacional 168 - Km 472.4 - C.C. 242, (S3000ZAA), Santa Fe, Argentina.
Prieto C; UNL, FBCB (School of Biochemistry and Biological Sciences), CBL (Biotechnological Center of Litoral), Biotechnological Development Laboratory, Ciudad Universitaria, Ruta Nacional 168 - Km 472.4 - C.C. 242 - (S3000ZAA), Santa Fe, Argentina; Cellargen Biotech S.R.L., Antonia Godoy 6369 (S3000ZAA), Santa Fe, Argentina; Biotecnofe S.A., PTLC, Ruta 168 Pje El Pozo, (CP3000), Santa Fe, Argentina. Electronic address: .
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Źródło :
Theriogenology [Theriogenology] 2021 Sep 15; Vol. 172, pp. 8-19. Date of Electronic Publication: 2021 May 23.
Typ publikacji :
Journal Article
MeSH Terms :
Chorionic Gonadotropin*/pharmacology
Gonadotropins, Equine*/pharmacology
Animals ; CHO Cells ; Cattle ; Cricetinae ; Cricetulus ; Female ; Horses ; Ovulation ; Pregnancy
Czasopismo naukowe
Tytuł :
Quantitative Analysis of the Potency of Equimolar Two-Drug Combinations and Combi-Molecules Involving Kinase Inhibitors In Vitro: The Concept of Balanced Targeting.
Autorzy :
Rao S; Cancer Drug Research Laboratory, Department of Medicine, Division of Medical Oncology, The Research Institute of the McGill University Health Center/Glen Hospital, Montreal, QC H4A 3J1, Canada.
Thibault B; Cancer Drug Research Laboratory, Department of Medicine, Division of Medical Oncology, The Research Institute of the McGill University Health Center/Glen Hospital, Montreal, QC H4A 3J1, Canada.
Peyrard L; Cancer Drug Research Laboratory, Department of Medicine, Division of Medical Oncology, The Research Institute of the McGill University Health Center/Glen Hospital, Montreal, QC H4A 3J1, Canada.
Larroque-Lombard AL; Cancer Drug Research Laboratory, Department of Medicine, Division of Medical Oncology, The Research Institute of the McGill University Health Center/Glen Hospital, Montreal, QC H4A 3J1, Canada.
Rupp M; Cancer Drug Research Laboratory, Department of Medicine, Division of Medical Oncology, The Research Institute of the McGill University Health Center/Glen Hospital, Montreal, QC H4A 3J1, Canada.
Thauvin C; Cancer Drug Research Laboratory, Department of Medicine, Division of Medical Oncology, The Research Institute of the McGill University Health Center/Glen Hospital, Montreal, QC H4A 3J1, Canada.
Jean-Claude BJ; Cancer Drug Research Laboratory, Department of Medicine, Division of Medical Oncology, The Research Institute of the McGill University Health Center/Glen Hospital, Montreal, QC H4A 3J1, Canada.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 03; Vol. 22 (17). Date of Electronic Publication: 2021 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Models, Biological*
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Neoplasms/*drug therapy
Protein Kinase Inhibitors/*pharmacology
A549 Cells ; Animals ; Cricetulus ; Female ; Humans ; Male ; Mice ; NIH 3T3 Cells ; Neoplasms/metabolism ; PC-3 Cells
Czasopismo naukowe
Tytuł :
Genotoxic effect induced by dried nicotiana tabacum leaves from tobacco barns (kiln-houses) in chinese hamster lung fibroblast cells (V79).
Autorzy :
Dalberto D; Laboratory of Genetic Toxicology, Postgraduate Program in Molecular and Cell Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil.
Nicolau CC; Laboratory of Genetic Toxicology, Postgraduate Program in Molecular and Cell Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil.
Rosa De Sousa M; Laboratory of Genetic Toxicology, Postgraduate Program in Molecular and Cell Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil.
Garcia ALH; Laboratory of Genetic Toxicology, Postgraduate Program in Molecular and Cell Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil.
Boaretto F; Laboratory of Genetic Toxicology, Postgraduate Program in Molecular and Cell Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil.
Picada JN; Laboratory of Genetic Toxicology, Postgraduate Program in Molecular and Cell Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil.
De Souza GMS; Ion Implantation Laboratory, Institute of Physics, Federal University of Rio Grande Do Sul (UFRGS), Porto Alegre, RS, Brazil.
Chytry P; Ion Implantation Laboratory, Institute of Physics, Federal University of Rio Grande Do Sul (UFRGS), Porto Alegre, RS, Brazil.
Dias JF; Ion Implantation Laboratory, Institute of Physics, Federal University of Rio Grande Do Sul (UFRGS), Porto Alegre, RS, Brazil.
Feistel CC; Pharmacognosy and Phytochemistry Laboratory. Postgraduate Program in Molecular and Cell Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil.
Ferraz ABF; Pharmacognosy and Phytochemistry Laboratory. Postgraduate Program in Molecular and Cell Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil.
Grivicich I; Laboratory of Cancer Biology. Postgraduate Program in Molecular and Cell Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil.
Da Silva J; Laboratory of Genetic Toxicology, Postgraduate Program in Molecular and Cell Biology Applied to Health, Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil.
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Źródło :
Journal of toxicology and environmental health. Part A [J Toxicol Environ Health A] 2021 Sep 02; Vol. 84 (17), pp. 689-701. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutagens/*toxicity
Plant Leaves/*chemistry
Tobacco/*chemistry
Animals ; Cell Line ; Comet Assay ; Cricetulus ; Micronucleus Tests ; Mutagenicity Tests
Czasopismo naukowe
Tytuł :
Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis.
Autorzy :
Sletten AC; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Davidson JW; Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Yagabasan B; Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Moores S; Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Schwaiger-Haber M; Department of Chemistry, Washington University in St. Louis, St. Louis, MO, USA.
Fujiwara H; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Gale S; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Jiang X; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Sidhu R; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Gelman S; Department of Chemistry, Washington University in St. Louis, St. Louis, MO, USA.
Zhao S; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Patti G; Department of Chemistry, Washington University in St. Louis, St. Louis, MO, USA.
Ory DS; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Schaffer JE; Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 01; Vol. 12 (1), pp. 5214. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Fatty Liver/*drug therapy
Fatty Liver/*metabolism
Protective Agents/*pharmacology
RNA, Small Nucleolar/*metabolism
Animals ; CHO Cells ; Cell Death/drug effects ; Cricetulus ; Diabetes Mellitus, Type 2/metabolism ; Fatty Liver/genetics ; Homeostasis ; Inflammation ; Lipid Metabolism ; Lipids/pharmacology ; Male ; Metabolic Syndrome/metabolism ; Mice ; Mice, Inbred C57BL ; Oxidative Stress/drug effects ; RNA, Long Noncoding ; RNA, Small Nucleolar/genetics ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
A simple, sensitive, and low-cost FACS assay for detecting antibodies against the native SARS-CoV-2 spike protein.
Autorzy :
Hambach J; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Stähler T; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Eden T; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Wendt D; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Tode N; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Haag F; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Tolosa E; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Altfeld M; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Fathi A; Section Infectious Diseases, I. Medical Clinic and Polyclinic, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Clinical Immunology of Infectious Diseases, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.
Dahlke C; Section Infectious Diseases, I. Medical Clinic and Polyclinic, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Clinical Immunology of Infectious Diseases, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.
Addo MM; Section Infectious Diseases, I. Medical Clinic and Polyclinic, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Clinical Immunology of Infectious Diseases, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany.; German Center for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.
Menzel S; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Koch-Nolte F; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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Źródło :
Immunity, inflammation and disease [Immun Inflamm Dis] 2021 Sep; Vol. 9 (3), pp. 905-917. Date of Electronic Publication: 2021 May 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/immunology
Spike Glycoprotein, Coronavirus*/immunology
Antibodies, Viral/*analysis
Adult ; Aged ; Aged, 80 and over ; Animals ; Cricetinae ; Cricetulus ; Flow Cytometry ; HEK293 Cells ; Humans ; Middle Aged ; SARS-CoV-2/immunology
Czasopismo naukowe
Tytuł :
Novel variant fibrinogen γp.C352R produced hypodysfibrinogenemia leading to a bleeding episode and failure of infertility treatment.
Autorzy :
Yoda M; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Kaido T; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Kamijo T; Department of Medical Sciences, Graduate School of Medicine, Science and Technology, Shinshu University, Matsumoto, Japan.; Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan.
Taira C; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Higuchi Y; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Arai S; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan. .
Okumura N; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.; Department of Clinical Laboratory Sciences, School of Health Sciences, Shinshu University, Matsumoto, Japan.
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Źródło :
International journal of hematology [Int J Hematol] 2021 Sep; Vol. 114 (3), pp. 325-333. Date of Electronic Publication: 2021 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
Alleles*
Mutation*
Afibrinogenemia/*genetics
Fibrinogen/*genetics
Hemorrhage/*blood
Hemorrhage/*etiology
Infertility/*etiology
Afibrinogenemia/blood ; Afibrinogenemia/complications ; Amino Acid Substitution ; Animals ; Blood Coagulation ; Blood Coagulation Tests ; CHO Cells ; Catalysis ; Cricetulus ; Fibrin/metabolism ; Hemorrhage/diagnosis ; Humans ; Infertility/diagnosis ; Infertility/therapy ; Polymerization ; Thrombin/metabolism
Czasopismo naukowe
Tytuł :
Modulating tyrosine sulfation of recombinant antibodies in CHO cell culture by host selection and sodium chlorate supplementation.
Autorzy :
Liu R; Process Cell Sciences, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Zhang Y; Process Cell Sciences, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Kumar A; Process Cell Sciences, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Huhn S; Process Cell Sciences, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Hullinger L; Process Cell Sciences, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Du Z; Process Cell Sciences, Merck & Co., Inc., Kenilworth, New Jersey, USA.
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Źródło :
Biotechnology journal [Biotechnol J] 2021 Sep; Vol. 16 (9), pp. e2100142. Date of Electronic Publication: 2021 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Dietary Supplements*
Tyrosine*
Animals ; CHO Cells ; Cell Culture Techniques ; Chlorates ; Cricetinae ; Cricetulus
Czasopismo naukowe
Tytuł :
Distinct transcription factor networks control neutrophil-driven inflammation.
Autorzy :
Khoyratty TE; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Ai Z; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Ballesteros I; Area of Cell & Developmental Biology, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Eames HL; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Mathie S; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Martín-Salamanca S; Area of Cell & Developmental Biology, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Wang L; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Hemmings A; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Willemsen N; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
von Werz V; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Zehrer A; Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center and Walter Brendel Center of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
Walzog B; Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center and Walter Brendel Center of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
van Grinsven E; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Hidalgo A; Area of Cell & Developmental Biology, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Udalova IA; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK. .
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Źródło :
Nature immunology [Nat Immunol] 2021 Sep; Vol. 22 (9), pp. 1093-1106. Date of Electronic Publication: 2021 Jul 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromatin Assembly and Disassembly/*genetics
Inflammation/*immunology
Neutrophils/*immunology
Transcriptional Activation/*genetics
Animals ; CHO Cells ; Cell Line ; Core Binding Factor Alpha 2 Subunit/metabolism ; Cricetulus ; Female ; Interferon Regulatory Factors/metabolism ; Kruppel-Like Factor 6/metabolism ; Mice ; Mice, Inbred C57BL ; Myocardial Infarction/immunology ; Myocardial Infarction/pathology ; Regulatory Factor X Transcription Factors/metabolism ; Transcription Factor RelB/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic/genetics
Czasopismo naukowe
Tytuł :
Stable overexpression of mutated PTEN in Chinese hamster ovary cells enhances their performance and therapeutic antibody production.
Autorzy :
Zhou Q; Institutes of Physical Science and Information Technology, Anhui University, Hefei, P. R. China.
Zhang Y; Institutes of Physical Science and Information Technology, Anhui University, Hefei, P. R. China.
Lu X; Institutes of Physical Science and Information Technology, Anhui University, Hefei, P. R. China.
Wang C; Institutes of Physical Science and Information Technology, Anhui University, Hefei, P. R. China.
Pei X; Institutes of Physical Science and Information Technology, Anhui University, Hefei, P. R. China.
Lu Y; Institutes of Physical Science and Information Technology, Anhui University, Hefei, P. R. China.
Cao C; Beijing Institute of Biotechnology, Beijing, P. R. China.
Xu C; Institutes of Physical Science and Information Technology, Anhui University, Hefei, P. R. China.
Zhang B; Institutes of Physical Science and Information Technology, Anhui University, Hefei, P. R. China.
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Źródło :
Biotechnology journal [Biotechnol J] 2021 Sep; Vol. 16 (9), pp. e2000623. Date of Electronic Publication: 2021 Jun 19.
Typ publikacji :
Journal Article
MeSH Terms :
Antibody Formation*
Phosphatidylinositol 3-Kinases*
Animals ; Batch Cell Culture Techniques ; CHO Cells ; Cricetinae ; Cricetulus
Czasopismo naukowe
Tytuł :
Quantifying the impact of cell culture media on CHO cell growth and protein production.
Autorzy :
Combe M; Department of Process Engineering and Applied Science, Dalhousie University, 1360 Barrington St., PO Box 15000, Halifax, NS B3H 4R2, Canada.
Sokolenko S; Department of Process Engineering and Applied Science, Dalhousie University, 1360 Barrington St., PO Box 15000, Halifax, NS B3H 4R2, Canada. Electronic address: .
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Źródło :
Biotechnology advances [Biotechnol Adv] 2021 Sep-Oct; Vol. 50, pp. 107761. Date of Electronic Publication: 2021 May 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Bioreactors*
Cell Culture Techniques*
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Culture Media ; Recombinant Proteins/genetics
Czasopismo naukowe

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