Autor: "Crick PJ" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Mining for Oxysterols in Cyp7b1 Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5.
Autorzy:: Meljon A; Swansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK. .; Institute for Global Food Security, Queens University Belfast, Stranmillis Road, Belfast BT9 5AG, UK. .
Crick PJ; Swansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK. peter.crick@gmail.com.
Yutuc E; Swansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK. .
Yau JL; Endocrinology Unit, BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK. .
Seckl JR; Endocrinology Unit, BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK. .
Theofilopoulos S; Swansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK. .; Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden. .
Arenas E; Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden. .
Wang Y; Swansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK. .
Griffiths WJ; Swansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK. .; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2019 Apr 13; Vol. 9 (4). Date of Electronic Publication: 2019 Apr 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain/*metabolism
Cytochrome P450 Family 7/*genetics
Hydroxycholesterols/*metabolism
Spastic Paraplegia, Hereditary/*metabolism
Steroid Hydroxylases/*genetics
Animals ; Cytochrome P450 Family 7/deficiency ; Hydroxycholesterols/blood ; Male ; Mice ; Spastic Paraplegia, Hereditary/blood ; Spastic Paraplegia, Hereditary/genetics ; Steroid Hydroxylases/deficiency

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Skocz do pozycji: 2.

Tytuł:: Developing an Enzyme-Assisted Derivatization Method for Analysis of C 27 Bile Alcohols and Acids by Electrospray Ionization-Mass Spectrometry.
Autorzy:: Abdel-Khalik J; Swansea University Medical School, ILS1 Building, Swansea University, Singleton Park, Swansea SA2 8PP, Wales, UK. .
Crick PJ
Yutuc E
Wang Y
Griffiths WJ; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2019 Feb 07; Vol. 24 (3). Date of Electronic Publication: 2019 Feb 07.
Typ publikacji:: Journal Article
MeSH Terms:: Bile Acids and Salts/*analysis
Cholestanols/*analysis
Spectrometry, Mass, Electrospray Ionization/*methods
Betaine/analogs & derivatives ; Bile Acids and Salts/chemistry ; Cholestanols/chemistry ; Chromatography, Liquid ; Hydroxysteroid Dehydrogenases/chemistry ; Mass Spectrometry ; Oxidation-Reduction ; Sterols/analysis ; Sterols/chemistry ; Substrate Specificity

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Skocz do pozycji: 3.

Tytuł:: An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway.
Autorzy:: Robertson KA; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.; SynthSys at Edinburgh University, The King's Buildings, Edinburgh, United Kingdom.
Hsieh WY; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Forster T; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.; SynthSys at Edinburgh University, The King's Buildings, Edinburgh, United Kingdom.
Blanc M; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.; École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Lu H; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Crick PJ; Institute of Mass Spectrometry, College of Medicine, Grove Building, Swansea University, Singleton Park, Swansea, United Kingdom.
Yutuc E; Institute of Mass Spectrometry, College of Medicine, Grove Building, Swansea University, Singleton Park, Swansea, United Kingdom.
Watterson S; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.; Northern Ireland Centre for Stratified Medicine, University of Ulster, C-Tric, Altnagelvin Campus, Londonderry, Ireland.
Martin K; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Integrative Physiology, Edinburgh, United Kingdom.
Griffiths SJ; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Enright AJ; EMBL - European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Yamamoto M; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Pradeepa MM; The Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom.
Lennox KA; Integrated DNA Technologies, Coralville, Iowa, United States of America.
Behlke MA; Integrated DNA Technologies, Coralville, Iowa, United States of America.
Talbot S; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Haas J; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Dölken L; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.; Institute of Virology, University of Würzburg, Würzburg, Germany.
Griffiths WJ; Institute of Mass Spectrometry, College of Medicine, Grove Building, Swansea University, Singleton Park, Swansea, United Kingdom.
Wang Y; Institute of Mass Spectrometry, College of Medicine, Grove Building, Swansea University, Singleton Park, Swansea, United Kingdom.
Angulo A; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.; Immunology Unit, Department of Cell Biology, Immunology, and Neurosciences, Medical School, University of Barcelona, Barcelona, Spain.
Ghazal P; Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom.; SynthSys at Edinburgh University, The King's Buildings, Edinburgh, United Kingdom.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2016 Mar 03; Vol. 14 (3), pp. e1002364. Date of Electronic Publication: 2016 Mar 03 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Interferon Regulatory Factor-1/*metabolism
Interferons/*physiology
MicroRNAs/*metabolism
Sterols/*biosynthesis
Virus Diseases/*immunology
Animals ; Mice, Inbred C57BL

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Skocz do pozycji: 4.

Tytuł:: Revised sample preparation for the analysis of oxysterols by enzyme-assisted derivatisation for sterol analysis (EADSA).
Autorzy:: Crick PJ; College of Medicine, Swansea University, Grove Building, Singleton Park, Swansea, SA2 8PP, UK.
Bentley TW
Wang Y
Griffiths WJ; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2015 Jul; Vol. 407 (17), pp. 5235-9. Date of Electronic Publication: 2015 Mar 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Solid Phase Extraction/*methods
Sterols/*analysis
Sterols/*blood
Cholesterol/analysis ; Cholesterol/blood ; Cholesterol/isolation & purification ; Cholesterol/metabolism ; Cholesterol Oxidase/metabolism ; Chromatography, Liquid/methods ; Humans ; Mass Spectrometry/methods ; Polymers/chemistry ; Sterols/isolation & purification ; Sterols/metabolism

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