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Wyświetlanie 1-20 z 271139
Tytuł:
Introduction to the virtual thematic issue on room-temperature biological crystallography.
Autorzy:
Steiner RA; King's College London, New Hunt's House - Guy's Campus, London SE1 1UL, United Kingdom.
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Źródło:
Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2023 Apr 01; Vol. 79 (Pt 4), pp. 79-81. Date of Electronic Publication: 2023 Mar 31.
Typ publikacji:
Journal Article
MeSH Terms:
Crystallography*
Crystallography, X-Ray ; Temperature
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Crystal Modifications of a Cyclic Guanosine Phosphorothioate Analogue, a Drug Candidate for Retinal Neurodegenerations.
Autorzy:
Pérez O; Chemical Processes and Pharmaceutical Development, Research Institutes of Sweden, Forskargatan 20 J, 151 36, Södertälje, Sweden.; Faculty of Pharmaceutical Sciences, University of Iceland, Saemundargata 2, 102, Reykjavík, Iceland.
Schipper N; Chemical Processes and Pharmaceutical Development, Research Institutes of Sweden, Forskargatan 20 J, 151 36, Södertälje, Sweden.
Leandri V; Chemical Processes and Pharmaceutical Development, Research Institutes of Sweden, Forskargatan 20 J, 151 36, Södertälje, Sweden.
Svensson PH; Chemical Processes and Pharmaceutical Development, Research Institutes of Sweden, Forskargatan 20 J, 151 36, Södertälje, Sweden.; Department of Chemistry, Applied Physical Chemistry, KTH Royal Institute of Technology, 100 44, Stockholm, Sweden.
Bohlin M; Chemical Processes and Pharmaceutical Development, Research Institutes of Sweden, Forskargatan 20 J, 151 36, Södertälje, Sweden.
Loftsson T; Faculty of Pharmaceutical Sciences, University of Iceland, Saemundargata 2, 102, Reykjavík, Iceland.
Bollmark M; Chemical Processes and Pharmaceutical Development, Research Institutes of Sweden, Forskargatan 20 J, 151 36, Södertälje, Sweden.
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Źródło:
ChemistryOpen [ChemistryOpen] 2023 Dec; Vol. 12 (12), pp. e202300141. Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Crystallography, X-Ray*
X-Ray Diffraction ; Solubility ; Crystallization ; Molecular Conformation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibitors of Transthyretin Amyloidosis: How to Rank Drug Candidates Using X-ray Crystallography Data.
Autorzy:
Leite JP; ICBAS-Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4050-313 Porto, Portugal.
Costa-Rodrigues D; ICBAS-Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4050-313 Porto, Portugal.; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.; IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.
Gales L; ICBAS-Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4050-313 Porto, Portugal.; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.; IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 18; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 18.
Typ publikacji:
Journal Article
MeSH Terms:
Prealbumin*/metabolism
Amyloid Neuropathies, Familial*/drug therapy
Humans ; Crystallography, X-Ray ; Amyloid/chemistry
SCR Disease Name:
Amyloidosis, Hereditary, Transthyretin-Related
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phanogracilins A–C, New Bibenzochromenones of Crinoid Phanogenia gracilis (Hartlaub, 1890).
Autorzy:
Vasileva, Elena A. (AUTHOR)
Berdyshev, Dmitrii V. (AUTHOR)
Mishchenko, Natalia P. (AUTHOR)
Gerasimenko, Andrey V. (AUTHOR)
Menchinskaya, Ekaterina S. (AUTHOR)
Pislyagin, Evgeniy A. (AUTHOR)
Chingizova, Ekaterina A. (AUTHOR)
Kaluzhskiy, Leonid A. (AUTHOR)
Dautov, Salim Sh. (AUTHOR)
Fedoreyev, Sergey A. (AUTHOR)
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Źródło:
Biomolecules (2218-273X). Feb2024, Vol. 14 Issue 2, p151. 18p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Influence of pozzolanic addition on strength and microstructure of metakaolin-based concrete.
Autorzy:
Bansal M; Civil Engineering Department, M.R.S.P.T.U, Bathinda (Punjab), India.
Bansal M; Civil Engineering Department, M.R.S.P.T.U, Bathinda (Punjab), India.
Bahrami A; Department of Building Engineering, Energy Systems and Sustainability Science, Faculty of Engineering and Sustainable Development, University of Gävle, Gävle, Sweden.
Krishan B; Civil Engineering Department, M.R.S.P.T.U, Bathinda (Punjab), India.
Garg R; Civil Engineering Department, Galgotias College of Engineering and Technology, Greater Noida (Uttar Pradesh), India.
Özkılıç YO; Department of Civil Engineering, Faculty of Engineering, Necmettin Erbakan University, Konya, Turkey.; Department of Civil Engineering, Lebanese American University, Byblos, Lebanon.
Althaqafi E; Civil Engineering Department, College of Engineering, King Khalid University, Abha, Saudi Arabia.
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Źródło:
PloS one [PLoS One] 2024 Apr 10; Vol. 19 (4), pp. e0298761. Date of Electronic Publication: 2024 Apr 10 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Bone Cements*
Glass Ionomer Cements*
Crystallography, X-Ray ; Intention ; Microscopy, Electron, Scanning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model.
Autorzy:
Tan B; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Zhang X; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
Ansari A; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Jadhav P; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Tan H; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Li K; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Chopra A; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Ford A; Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
Chi X; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
Ruiz FX; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Arnold E; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Deng X; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.; Oklahoma Center for Respiratory and Infectious Diseases, Oklahoma State University, Stillwater, OK 74078, USA.
Wang J; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. 1434-1440. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Coronavirus Papain-Like Proteases*/antagonists & inhibitors
Coronavirus Papain-Like Proteases*/chemistry
COVID-19*
SARS-CoV-2*/drug effects
SARS-CoV-2*/enzymology
Coronavirus Protease Inhibitors*/administration & dosage
Coronavirus Protease Inhibitors*/chemistry
Coronavirus Protease Inhibitors*/pharmacology
Drug Design*
COVID-19 Drug Treatment*
Animals ; Mice ; Disease Models, Animal ; Administration, Oral ; Crystallography, X-Ray ; Structure-Activity Relationship ; Viral Load/drug effects ; Male ; Mice, Inbred C57BL ; Mice, Inbred BALB C
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural Insights into Plant Viruses Revealed by Small-Angle X-ray Scattering and Atomic Force Microscopy.
Autorzy:
Shtykova EV; National Research Centre, 'Kurchatov Institute', Moscow 123098, Russia.; Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow 119071, Russia.
Dubrovin EV; Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow 119071, Russia.; Faculty of Physics, Lomonosov Moscow State University, Moscow 119991, Russia.
Ksenofontov AL; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119991, Russia.
Gifer PK; Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow 119071, Russia.
Petoukhov MV; National Research Centre, 'Kurchatov Institute', Moscow 123098, Russia.; Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow 119071, Russia.
Tokhtar VK; Scientific and Educational Center, Botanical Garden of the National Research University 'BelSU', Belgorod 308033, Russia.
Sapozhnikova IM; Institute of Chemical Engineering, Ural Federal University Named after the First President of Russia B. N. Yeltsin, Ekaterinburg 620002, Russia.
Stavrianidi AN; Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow 119071, Russia.; Faculty of Physics, Lomonosov Moscow State University, Moscow 119991, Russia.
Kordyukova LV; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119991, Russia.
Batishchev OV; Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow 119071, Russia.
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Źródło:
Viruses [Viruses] 2024 Mar 10; Vol. 16 (3). Date of Electronic Publication: 2024 Mar 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Plant Viruses*
X-Ray Diffraction ; Cryoelectron Microscopy ; Scattering, Small Angle ; Microscopy, Atomic Force/methods ; X-Rays ; Crystallography, X-Ray
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Comparative Study of New Fluorescent Anthraquinone and Benzanthrone α-Aminophosphonates: Synthesis, Spectroscopy, Toxicology, X-ray Crystallography, and Microscopy of Opisthorchis felineus .
Autorzy:
Maļeckis A; Institute of Chemistry and Chemical Technology, Faculty of Natural Sciences and Technology, Riga Technical University, P. Valdena Str. 3, LV-1048 Riga, Latvia.
Cvetinska M; Institute of Chemistry and Chemical Technology, Faculty of Natural Sciences and Technology, Riga Technical University, P. Valdena Str. 3, LV-1048 Riga, Latvia.
Kirjušina M; Department of Ecology, Institute of Life Sciences and Technology, Daugavpils University, LV-5401 Daugavpils, Latvia.
Mežaraupe L; Department of Ecology, Institute of Life Sciences and Technology, Daugavpils University, LV-5401 Daugavpils, Latvia.
Kecko S; Department of Ecology, Institute of Life Sciences and Technology, Daugavpils University, LV-5401 Daugavpils, Latvia.
Gavarāne I; Department of Ecology, Institute of Life Sciences and Technology, Daugavpils University, LV-5401 Daugavpils, Latvia.
Kiyan V; Laboratory of Biodiversity and Genetic Resources, National Center for Biotechnology, 13/5 Kurgalzhynskoye Road, Astana 010000, Kazakhstan.
Lider L; Faculty of Veterinary Medicine and Animal Husbandry Technology, S. Seifullin Kazakh Agro Technical Research University, 62 Zhenis Avenue, Astana 010011, Kazakhstan.
Pavlova V; Department of Ecology, Institute of Life Sciences and Technology, Daugavpils University, LV-5401 Daugavpils, Latvia.
Savicka M; Department of Ecology, Institute of Life Sciences and Technology, Daugavpils University, LV-5401 Daugavpils, Latvia.
Belyakov S; Latvian Institute of Organic Synthesis, Aizkraukles Str. 21, LV-1006 Riga, Latvia.
Kirilova E; Department of Environment and Technologies, Faculty of Natural Sciences and Healthcare, Daugavpils University, LV-5401 Daugavpils, Latvia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 04; Vol. 29 (5). Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Opisthorchis*
Organophosphonates*/chemistry
Benz(a)Anthracenes*
Animals ; Crystallography, X-Ray ; Magnetic Resonance Spectroscopy ; Microscopy, Confocal/methods ; Anthraquinones
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Dinuclear Copper(II) Complex Electrochemically Obtained via the Endogenous Hydroxylation of a Carbamate Schiff Base Ligand: Synthesis, Structure and Catalase Activity.
Autorzy:
Fernández-Fariña S; Departamento de Química Inorgánica, Facultade de Ciencias, Campus Terra, Universidade de Santiago de Compostela, 27002 Lugo, Spain.
Velo-Heleno I; Departamento de Química Inorgánica, Facultade de Química, Campus Vida, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Rodríguez-Silva L; Departamento de Química Inorgánica, Facultade de Ciencias, Campus Terra, Universidade de Santiago de Compostela, 27002 Lugo, Spain.
Maneiro M; Departamento de Química Inorgánica, Facultade de Ciencias, Campus Terra, Universidade de Santiago de Compostela, 27002 Lugo, Spain.
González-Noya AM; Departamento de Química Inorgánica, Facultade de Química, Campus Vida, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Pedrido R; Departamento de Química Inorgánica, Facultade de Química, Campus Vida, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 10; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 10.
Typ publikacji:
Journal Article
MeSH Terms:
Copper*/chemistry
Schiff Bases*/chemistry
Hydroxylation ; Ligands ; Catalase ; Carbamates ; Crystallography, X-Ray
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis and Investigations of the Antitumor Effects of First-Row Transition Metal(II) Complexes Supported by Two Fluorinated and Non-Fluorinated β-Diketonates.
Autorzy:
Pellei M; School of Science and Technology-Chemistry Division, University of Camerino, Via Madonna delle Carceri (ChIP), Camerino, 62032 Macerata, Italy.
Del Gobbo J; School of Science and Technology-Chemistry Division, University of Camerino, Via Madonna delle Carceri (ChIP), Camerino, 62032 Macerata, Italy.
Caviglia M; School of Science and Technology-Chemistry Division, University of Camerino, Via Madonna delle Carceri (ChIP), Camerino, 62032 Macerata, Italy.
Gandin V; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35131 Padova, Italy.
Marzano C; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35131 Padova, Italy.
Karade DV; Department of Chemistry and Biochemistry, The University of Texas at Arlington, P.O. Box 19065, Arlington, TX 76019, USA.
Noonikara Poyil A; Department of Chemistry and Biochemistry, The University of Texas at Arlington, P.O. Box 19065, Arlington, TX 76019, USA.
Dias HVR; Department of Chemistry and Biochemistry, The University of Texas at Arlington, P.O. Box 19065, Arlington, TX 76019, USA.
Santini C; School of Science and Technology-Chemistry Division, University of Camerino, Via Madonna delle Carceri (ChIP), Camerino, 62032 Macerata, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 07; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Copper*/chemistry
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Humans ; Metals/chemistry ; Zinc/chemistry ; Iron/chemistry ; Ferrous Compounds ; Ligands ; Crystallography, X-Ray ; Molecular Structure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multivariate estimation of substructure amplitudes for a single-wavelength anomalous diffraction experiment.
Autorzy:
Pannu NS; Department of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
Skubák P; Department of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
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Źródło:
Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2023 Apr 01; Vol. 79 (Pt 4), pp. 339-344. Date of Electronic Publication: 2023 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Crystallography, X-Ray*
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A workflow for deriving chemical entities from crystallographic data and its application to the Crystallography Open Database.
Autorzy:
Vaitkus, Antanas (AUTHOR)
Merkys, Andrius (AUTHOR)
Sander, Thomas (AUTHOR)
Quirós, Miguel (AUTHOR)
Thiessen, Paul A. (AUTHOR)
Bolton, Evan E. (AUTHOR)
Gražulis, Saulius (AUTHOR)
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Źródło:
Journal of Cheminformatics. 12/19/2023, Vol. 15 Issue 1, p1-15. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Growing Crystals for X-ray Free-Electron Laser Structural Studies of Biomolecules and Their Complexes.
Autorzy:
Nanev CN; Rostislaw Kaischew Institute of Physical Chemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Saridakis E; Institute of Nanoscience and Nanotechnology, National Centre for Scientific Research 'Demokritos', Ag. Paraskevi, 15310 Athens, Greece.
Chayen NE; Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London W12 0NN, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 15; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Electrons*
Synchrotrons*
X-Rays ; Crystallography, X-Ray ; Proteins ; Lasers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Discovery of the SHP2 allosteric inhibitor 2-((3R,4R)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-5-(2,3-dichlorophenyl)-3-methylpyrrolo[2,1-f][1,2,4] triazin-4(3H)-one.
Autorzy:
Luo Y; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Li J; Division of Medicinal Chemistry, PharmaBlock Sciences (Nanjing), Inc., Nanjing, China.
Zong Y; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Sun M; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Zheng W; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Zhu J; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China.; Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Liu L; Division of Medicinal Chemistry, PharmaBlock Sciences (Nanjing), Inc., Nanjing, China.
Liu B; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China.; Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 398-404.
Typ publikacji:
Journal Article
MeSH Terms:
Triazines*/pharmacology
Crystallography, X-Ray ; Protein Tyrosine Phosphatase, Non-Receptor Type 11
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor.
Autorzy:
Goto M; Department of Molecular Bioscience, Toho University, Japan.
Sakamoto N; Department of Chemistry, Toho University, Japan.
Higashi S; Department of Chemistry, Toho University, Japan.
Kawata R; Department of Molecular Bioscience, Toho University, Japan.
Nagatsu K; Department of Molecular Bioscience, Toho University, Japan.
Saito R; Department of Chemistry, Toho University, Japan.; Research Center for Materials with Integrated Properties, Toho University, Japan.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2219038.
Typ publikacji:
Journal Article
MeSH Terms:
Ricin*/chemistry
Ricin*/genetics
Ricin*/metabolism
Pterins/chemistry ; Pterins/pharmacology ; Crystallography, X-Ray ; Peptides
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1.
Autorzy:
Das D; XPose Therapeutics, Inc., San Carlos, CA 94070, USA.; Accelero Biostructures, Inc., San Carlos, CA 94070, USA.
Duncton MAJ; XPose Therapeutics, Inc., San Carlos, CA 94070, USA.
Georgiadis TM; XPose Therapeutics, Inc., San Carlos, CA 94070, USA.
Pellicena P; XPose Therapeutics, Inc., San Carlos, CA 94070, USA.
Clark J; Mitchell Cancer Institute and Department of Pharmacology, University of South Alabama, Mobile, AL 36604, USA.
Sobol RW; Mitchell Cancer Institute and Department of Pharmacology, University of South Alabama, Mobile, AL 36604, USA.; Department of Pathology & Laboratory Medicine, Warrant Alpert Medical School & Legorreta Cancer Center, Brown University, Providence, RI 02912, USA.
Georgiadis MM; XPose Therapeutics, Inc., San Carlos, CA 94070, USA.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
King-Underwood J; XPose Therapeutics, Inc., San Carlos, CA 94070, USA.
Jobes DV; XPose Therapeutics, Inc., San Carlos, CA 94070, USA.; Mid-Atlantic BioTherapeutics, Inc., Doylestown, PA 18902, USA.
Chang C; Department of BioSciences, Rice University, Houston, TX 77251, USA.
Gao Y; Department of BioSciences, Rice University, Houston, TX 77251, USA.
Deacon AM; XPose Therapeutics, Inc., San Carlos, CA 94070, USA.; Accelero Biostructures, Inc., San Carlos, CA 94070, USA.
Wilson DM 3rd; XPose Therapeutics, Inc., San Carlos, CA 94070, USA.; Biomedical Research Institute, Hasselt University, 3500 Diepenbeek, Belgium.; Belgium & Boost Scientific, 3550 Heusden-Zolder, Belgium.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 23; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
DNA-Directed DNA Polymerase*/metabolism
Drug Discovery*
Binding Sites ; Endonucleases/metabolism ; Crystallography, X-Ray ; DNA-(Apurinic or Apyrimidinic Site) Lyase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The universal suppressor mutation restores membrane budding defects in the HSV-1 nuclear egress complex by stabilizing the oligomeric lattice.
Autorzy:
Draganova, Elizabeth B. (AUTHOR)
Wang, Hui (AUTHOR)
Wu, Melanie (AUTHOR)
Liao, Shiqing (AUTHOR)
Vu, Amber (AUTHOR)
Gonzalez-Del Pino, Gonzalo L. (AUTHOR)
Zhou, Z. Hong (AUTHOR)
Roller, Richard J. (AUTHOR)
Heldwein, Ekaterina E. (AUTHOR)
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Źródło:
PLoS Pathogens. 1/16/2024, Vol. 20 Issue 1, p1-33. 33p.
Czasopismo naukowe
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