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Wyszukujesz frazę ""Cysteine Endopeptidases"" wg kryterium: Temat


Tytuł:
Production and properties of adhesin-free gingipain proteinase RgpA.
Autorzy:
Mahmud ASM; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, Parkville, VIC, 3010, Australia.
Seers CA; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, Parkville, VIC, 3010, Australia.
Huq NL; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, Parkville, VIC, 3010, Australia.
Zhang L; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, Parkville, VIC, 3010, Australia.
Butler CA; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, Parkville, VIC, 3010, Australia.
Moore C; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, Parkville, VIC, 3010, Australia.
Cross KJ; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, Parkville, VIC, 3010, Australia.
Reynolds EC; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, Parkville, VIC, 3010, Australia. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 04; Vol. 13 (1), pp. 10780. Date of Electronic Publication: 2023 Jul 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cysteine Endopeptidases*/metabolism
Peptide Hydrolases*
Gingipain Cysteine Endopeptidases ; Adhesins, Bacterial/chemistry ; Catalytic Domain ; Porphyromonas gingivalis/metabolism ; Hemagglutinins/chemistry
Czasopismo naukowe
Tytuł:
Purification of RgpA from external outer membrane vesicles of Porphyromonas gingivalis.
Autorzy:
Castillo DM; Universidad El Bosque, Vicerrectoría de investigaciones, Facultad de Odontología, Unidad de Investigación Básica Oral (UIBO), Av. Carrera 9 No 131A - 02, Bogotá D.C, Colombia. Electronic address: .
Castillo Y; Universidad El Bosque, Vicerrectoría de investigaciones, Facultad de Odontología, Unidad de Investigación Básica Oral (UIBO), Av. Carrera 9 No 131A - 02, Bogotá D.C, Colombia.
Delgadillo NA; Universidad El Bosque, Vicerrectoría de investigaciones, Facultad de Odontología, Unidad de Investigación Básica Oral (UIBO), Av. Carrera 9 No 131A - 02, Bogotá D.C, Colombia.
Neuta Y; Universidad El Bosque, Vicerrectoría de investigaciones, Facultad de Odontología, Unidad de Investigación Básica Oral (UIBO), Av. Carrera 9 No 131A - 02, Bogotá D.C, Colombia.
Lafaurie GI; Universidad El Bosque, Vicerrectoría de investigaciones, Facultad de Odontología, Unidad de Investigación Básica Oral (UIBO), Av. Carrera 9 No 131A - 02, Bogotá D.C, Colombia.
Romero-Sánchez C; Universidad El Bosque, School of Dentistry, Cellular and Molecular Immunilogy Group/INMUBO, Av. Carrera 9 No 131A - 02, Bogotá D.C, Colombia; Hospital Militar Central, Rheumatology and Immunology Department/Clinical Immunology Group/Universidad Militar Nueva Granada, School of Medicine, Transversal 3(a) # 49-00, Bogotá D.C, Colombia.
Castellanos JE; Universidad Nacional de Colombia, Facultad de Odontología, Carrera 30 No. 45-03, Edificio 210, Oficina 301, Bogotá D.C, Colombia.
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Źródło:
Anaerobe [Anaerobe] 2022 Oct; Vol. 77, pp. 102647. Date of Electronic Publication: 2022 Sep 16.
Typ publikacji:
Journal Article
MeSH Terms:
Porphyromonas gingivalis*/metabolism
Cysteine Endopeptidases*/metabolism
Rats ; Animals ; Gingipain Cysteine Endopeptidases ; Adhesins, Bacterial/metabolism ; Hemagglutinins/chemistry ; Hemagglutinins/metabolism
Czasopismo naukowe
Tytuł:
A non-peptide-based fluorescent probe capable of sensitively visualizing asparagine endopeptidase.
Autorzy:
Li K; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. .
Hou Y; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. .
Han J; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. .
Lv C; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. .
Liu W; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. .
Du J; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. .
Sun W; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. .
Fan J; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. .; Ningbo Institute of Dalian University of Technology, Ningbo 315016, China.
Peng X; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. .
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Źródło:
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Mar 12; Vol. 60 (22), pp. 3031-3034. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Fluorescent Dyes*
Cysteine Endopeptidases*
Czasopismo naukowe
Tytuł:
UHPLC-MS/MS Assay for Quantification of Legubicin, a Novel Doxorubicin-Based Legumain-Activated Prodrug, and Its Application to Pharmacokinetic and Tissue Distribution Studies.
Autorzy:
Ma L; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China.; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.
Yu Q; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.
Zhuang M; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.
Yang C; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.
Liu Y; Shanghai Affinity Bio-Pharmaceuticals Co., Ltd., Shanghai 201203, China.
Li Y; Shanghai Affinity Bio-Pharmaceuticals Co., Ltd., Shanghai 201203, China.
Liu C; Shanghai Affinity Bio-Pharmaceuticals Co., Ltd., Shanghai 201203, China.
Shen X; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China.
Chang Y; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 08; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Prodrugs*/chemistry
Neoplasms*
Cysteine Endopeptidases*
Mice ; Rats ; Animals ; Chromatography, High Pressure Liquid ; Tissue Distribution ; Tandem Mass Spectrometry ; Doxorubicin/chemistry ; Albumins
Czasopismo naukowe
Tytuł:
Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses.
Autorzy:
Hu X; Department of Dermatology, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan, 410000, China.
Hu Z; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
Zhang H; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China; Department of Neurosurgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, Chongqing, 400016, China.
Zhang N; Department of Neurosurgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, Chongqing, 400016, China; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, 430074, China.
Feng H; Department of Dermatology, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan, 410000, China.
Jia X; Department of Pathology, Lhasa People's Hospital, Lhasa, Tibet Autonomous Region, 850001, China.
Zhang C; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China. Electronic address: .
Cheng Q; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China. Electronic address: .
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Źródło:
Cancer letters [Cancer Lett] 2024 Jan 28; Vol. 581, pp. 216466. Date of Electronic Publication: 2023 Nov 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Melanoma*/genetics
Melanoma*/therapy
Skin Neoplasms*/genetics
Skin Neoplasms*/therapy
Cysteine Endopeptidases*/genetics
Humans ; Multiomics ; Prognosis ; Single-Cell Gene Expression Analysis ; Transcriptome ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Weighted gene co-expression network analysis and machine learning identified the lipid metabolism-related gene LGMN as a novel biomarker for keloid.
Autorzy:
Wang Q; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Huang X; Shanghai Key Laboratory of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Orthodontics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.
Zeng S; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhou R; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang D; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło:
Experimental dermatology [Exp Dermatol] 2024 Jan; Vol. 33 (1), pp. e14974. Date of Electronic Publication: 2023 Nov 06.
Typ publikacji:
Journal Article
MeSH Terms:
Lipid Metabolism*/genetics
Keloid*/genetics
Cysteine Endopeptidases*
Humans ; Machine Learning ; Biomarkers
Czasopismo naukowe
Tytuł:
Lysosome-targeting and legumain-triggered Ga-labeled probe for enhanced tumor PET imaging.
Autorzy:
Hua D; Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Xi H; Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Xie Q; Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Cai S; Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Zhou Y; Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Hu X; Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Qiu L; Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Lin J; Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Apr 09; Vol. 703, pp. 149646. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Gallium Radioisotopes*
Neoplasms*/diagnostic imaging
Cysteine Endopeptidases*
Humans ; Positron-Emission Tomography/methods ; Lysosomes ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
c-Src regulates δ-secretase activation and truncated Tau production by phosphorylating the E3 ligase Traf6.
Autorzy:
Jiang Y; Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li L; Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu R; Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu L; Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang B; Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang JZ; Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu, China.
Liu R; Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu F; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA. Electronic address: .
Wang J; Department of Immunology School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
Wang X; Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu, China; Shenzhen Huazhong University of Science and Technology Research Institute, Shenzhen, China. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Dec; Vol. 299 (12), pp. 105462. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Cysteine Endopeptidases*/metabolism
src-Family Kinases*/antagonists & inhibitors
src-Family Kinases*/metabolism
tau Proteins*/metabolism
TNF Receptor-Associated Factor 6*/chemistry
TNF Receptor-Associated Factor 6*/metabolism
Ubiquitin-Protein Ligases*/metabolism
Animals ; Humans ; Mice ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Phosphorylation ; Enzyme Activation ; Phenylalanine ; Ubiquitination
Czasopismo naukowe
Tytuł:
Asparagine endopeptidase protects podocytes in adriamycin-induced nephropathy by regulating actin dynamics through cleaving transgelin.
Autorzy:
Qiu Y; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.
Lei C; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.
Zeng J; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.
Xie Y; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.
Cao Y; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.
Yuan Q; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.
Su H; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.
Zhang Z; Department of Neurology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Zhang C; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China. Electronic address: .
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Źródło:
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2023 Nov 01; Vol. 31 (11), pp. 3337-3354. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glomerulosclerosis, Focal Segmental*/chemically induced
Glomerulosclerosis, Focal Segmental*/genetics
Glomerulosclerosis, Focal Segmental*/metabolism
Kidney Diseases*/metabolism
Podocytes*/metabolism
Cysteine Endopeptidases*/genetics
Animals ; Humans ; Mice ; Actins/genetics ; Actins/metabolism ; Doxorubicin/adverse effects ; Mice, Knockout ; Microfilament Proteins/genetics ; Microfilament Proteins/metabolism ; Proteinuria/metabolism ; Proteinuria/pathology
Czasopismo naukowe
Tytuł:
Dual-Targeting PET Tracers Enable Enzyme-Mediated Self-Assembly for the PET Imaging of Legumain Activity.
Autorzy:
Lu C; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, China.
Li K; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, China.
Xi H; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, China.
Hua D; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, China.
Li H; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, China.
Gao F; Laboratory for Experimental Teratology of the Ministry of Education and Biomedical Isotope Research Center School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
Qiu L; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, China.
Lin J; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, China.
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Źródło:
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2023 Sep 27; Vol. 15 (38), pp. 44654-44664. Date of Electronic Publication: 2023 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Cysteine Endopeptidases*
Liver Neoplasms*
Humans ; Reducing Agents ; Glutamic Acid
Czasopismo naukowe
Tytuł:
Immunoproteasome-specific subunit PSMB9 induction is required to regulate cellular proteostasis upon mitochondrial dysfunction.
Autorzy:
Kim M; IMol Polish Academy of Sciences, Warsaw, Poland.
Serwa RA; IMol Polish Academy of Sciences, Warsaw, Poland.; ReMedy International Research Agenda Unit, IMol Polish Academy of Sciences, Warsaw, Poland.
Samluk L; Centre of New Technologies, University of Warsaw, Warsaw, Poland.
Suppanz I; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Kodroń A; IMol Polish Academy of Sciences, Warsaw, Poland.; ReMedy International Research Agenda Unit, IMol Polish Academy of Sciences, Warsaw, Poland.
Stępkowski TM; IMol Polish Academy of Sciences, Warsaw, Poland.; ReMedy International Research Agenda Unit, IMol Polish Academy of Sciences, Warsaw, Poland.
Elancheliyan P; IMol Polish Academy of Sciences, Warsaw, Poland.
Tsegaye B; IMol Polish Academy of Sciences, Warsaw, Poland.
Oeljeklaus S; Department of Biochemistry, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany.
Wasilewski M; IMol Polish Academy of Sciences, Warsaw, Poland.
Warscheid B; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.; Department of Biochemistry, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany.
Chacinska A; IMol Polish Academy of Sciences, Warsaw, Poland. .; ReMedy International Research Agenda Unit, IMol Polish Academy of Sciences, Warsaw, Poland. .
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Źródło:
Nature communications [Nat Commun] 2023 Jul 11; Vol. 14 (1), pp. 4092. Date of Electronic Publication: 2023 Jul 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proteasome Endopeptidase Complex*
Proteostasis*
Cysteine Endopeptidases*/metabolism
Humans ; Cytoplasm ; Mitochondria ; Peptide Elongation Factor 1
Czasopismo naukowe
Tytuł:
SENP1 modulates chronic intermittent hypoxia-induced inflammation of microglia and neuronal injury by inhibiting TOM1 pathway.
Autorzy:
Wang H; Department of Respiratory Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China. Electronic address: .
Wang X; Research Center of Respiratory Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Shen Y; Department of Respiratory Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Wang Y; Department of Respiratory Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Yang T; Department of Respiratory Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Sun J; Department of Respiratory Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Liu S; Department of Respiratory Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2023 Jun; Vol. 119, pp. 110230. Date of Electronic Publication: 2023 May 01.
Typ publikacji:
Journal Article
MeSH Terms:
Cysteine Endopeptidases*/genetics
Cysteine Endopeptidases*/metabolism
Microglia*/metabolism
Sleep Apnea, Obstructive*/metabolism
Animals ; Mice ; Endopeptidases ; Hypoxia/metabolism ; Inflammation/metabolism ; Mice, Inbred C57BL ; Neuroinflammatory Diseases ; Peptide Hydrolases/metabolism
Czasopismo naukowe
Tytuł:
Allosteric regulation of Senecavirus A 3Cpro proteolytic activity by an endogenous phospholipid.
Autorzy:
Zhao HF; School of Life Sciences, University of Science and Technology of China, Hefei, China.; Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
Meng L; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Geng Z; School of Life Sciences, University of Science and Technology of China, Hefei, China.
Gao ZQ; School of Life Sciences, University of Science and Technology of China, Hefei, China.
Dong YH; Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
Wang HW; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Zhang H; Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 May 30; Vol. 19 (5), pp. e1011411. Date of Electronic Publication: 2023 May 30 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Cysteine Endopeptidases*/metabolism
Picornaviridae*
Animals ; Swine ; 3C Viral Proteases/metabolism ; Peptide Hydrolases/metabolism ; Allosteric Regulation ; Phospholipids ; Viral Proteins/metabolism
SCR Organism:
Senecavirus A
Czasopismo naukowe
Tytuł:
SENP3 mediates the activation of the Wnt/β-catenin signaling pathway to accelerate the growth and metastasis of oesophagal squamous cell carcinoma in mice.
Autorzy:
Wang P; Department of Thoracic Surgery, the Fourth Hospital of Hebei Medical University, No.12 Jian-Kang Road, Chang-An District, Shijiazhuang, 050011, People's Republic of China.
Yang L; Department of Respiratory Medicine, the Second Hospital of Hebei Medical University, Shijiazhuang, 050011, People's Republic of China.
Guo Y; Department of Radiotherapy, the Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, People's Republic of China.
Qi S; Department of Thoracic Surgery, Gucheng County Hospital in Hebei Province, Hengshui, 253800, People's Republic of China.
Liang J; Department of Cancer, the Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, People's Republic of China.
Tian G; Medical Record Room, the Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, People's Republic of China.
Tian Z; Department of Thoracic Surgery, the Fourth Hospital of Hebei Medical University, No.12 Jian-Kang Road, Chang-An District, Shijiazhuang, 050011, People's Republic of China. dr_.
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Źródło:
Functional & integrative genomics [Funct Integr Genomics] 2024 Feb 22; Vol. 24 (2), pp. 40. Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Squamous Cell*/metabolism
Esophageal Neoplasms*/genetics
Esophageal Squamous Cell Carcinoma*/genetics
Esophageal Squamous Cell Carcinoma*/metabolism
Esophageal Squamous Cell Carcinoma*/pathology
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cysteine Endopeptidases/genetics ; Cysteine Endopeptidases/metabolism ; Gene Expression Regulation, Neoplastic ; Wnt Signaling Pathway/genetics
Czasopismo naukowe
Tytuł:
SENP3 Promotes Mantle Cell Lymphoma Development through Regulating Wnt10a Expression.
Autorzy:
Ma YN; Department of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.; Department of Hematology, the Third Affiliated Hospital (Daping Hospital), Third Military Medical University (Army Medical University), Chongqing, 400042, China.
Zou YD; Department of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Liu ZL; Department of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Wu GX; Department of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Zhou YZ; Department of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Luo CX; Department of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Huang XT; Department of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Xie ML; Department of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Xu SN; Department of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Li X; Department of Hematology, the Third Affiliated Hospital (Daping Hospital), Third Military Medical University (Army Medical University), Chongqing, 400042, China. .
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Źródło:
Current medical science [Curr Med Sci] 2024 Feb; Vol. 44 (1), pp. 134-143. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Lymphoma, Mantle-Cell*/genetics
Lymphoma, Mantle-Cell*/drug therapy
Lymphoma, Mantle-Cell*/pathology
Adult ; Animals ; Humans ; Mice ; Apoptosis/genetics ; Cysteine Endopeptidases/genetics ; Cysteine Endopeptidases/metabolism ; Disease Models, Animal ; Mice, Nude ; Nerve Tissue Proteins ; Peptide Hydrolases/therapeutic use ; RNA, Messenger ; Wnt Proteins/therapeutic use
Czasopismo naukowe
Tytuł:
Applying the bioisosterism strategy to obtain lead compounds against SARS-CoV-2 cysteine proteases: An in-silico approach.
Autorzy:
Borba JRBM; João Ricardo Bueno de Morais Borba, Laboratory of Molecular Modeling and Computer Simulation - MolMod-CS, Institute of Chemistry, Federal University of Alfenas - UNIFAL-MG, Alfenas, Brazil.
de Araújo LP; Leonardo Pereira de Araújo, Laboratory of Molecular Modeling and Computer Simulation - MolMod-CS, Institute of Chemistry, Federal University of Alfenas - UNIFAL-MG, Alfenas, Brazil.
Veloso MP; Marcia Paranho Veloso, Laboratory of Molecular Modeling and Computer Simulation - MolMod-CS, Institute of Chemistry, Federal University of Alfenas - UNIFAL-MG, Alfenas, Brazil.
da Silveira NJF; Nelson José Freitas da Silveira, Laboratory of Molecular Modeling and Computer Simulation - MolMod-CS, Institute of Chemistry, Federal University of Alfenas - UNIFAL-MG, Alfenas, Brazil.
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Źródło:
Journal of computational chemistry [J Comput Chem] 2024 Jan 05; Vol. 45 (1), pp. 35-46. Date of Electronic Publication: 2023 Aug 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*
Cysteine Proteases*/metabolism
Humans ; SARS-CoV-2/metabolism ; Molecular Docking Simulation ; Protease Inhibitors/pharmacology ; Protease Inhibitors/chemistry ; Cysteine Endopeptidases/chemistry ; Cysteine Endopeptidases/metabolism ; Molecular Dynamics Simulation
Czasopismo naukowe
Tytuł:
SENP1 knockdown-mediated CTCF SUMOylation enhanced its stability and alleviated lipopolysaccharide-evoked inflammatory injury in human lung fibroblasts via regulation of FOXA2 transcription.
Autorzy:
Kang L; Neonatal Intensive Care Unit, Zhumadian Central Hospital, 463100 Zhumadian, Henan Province, China. Electronic address: .
Wang X; Neonatal Intensive Care Unit, Zhumadian Central Hospital, 463100 Zhumadian, Henan Province, China.
Wang J; Department of Clinical Laboratory, Zhumadian Central Hospital, 463100 Zhumadian, Henan Province, China.
Guo J; Neonatal Intensive Care Unit, Henan Children's Hospital, 450000 Zhengzhou, Henan Province, China.
Zhang W; Neonatal Intensive Care Unit, Zhumadian Central Hospital, 463100 Zhumadian, Henan Province, China.
Lei R; Department of Neonatology, Zhumadian Central Hospital, 463100 Zhumadian, Henan Province, China.
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Źródło:
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2024 Jan; Vol. 1868 (1), pp. 130500. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*
Peptide Hydrolases*/metabolism
Infant, Newborn ; Humans ; CCCTC-Binding Factor/genetics ; CCCTC-Binding Factor/metabolism ; Sumoylation ; Cysteine Endopeptidases/genetics ; Cysteine Endopeptidases/metabolism ; Fibroblasts/metabolism ; Lung/metabolism ; Anti-Inflammatory Agents ; Hepatocyte Nuclear Factor 3-beta/genetics ; Hepatocyte Nuclear Factor 3-beta/metabolism
Czasopismo naukowe
Tytuł:
A naturally occurring G11S mutation in the 3C-like protease from the SARS-CoV-2 virus dramatically weakens the dimer interface.
Autorzy:
Wang G; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
Venegas FA; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
Rueda AM; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
Weerasinghe NW; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
Uggowitzer KA; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
Thibodeaux CJ; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
Moitessier N; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
Mittermaier AK; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
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Źródło:
Protein science : a publication of the Protein Society [Protein Sci] 2024 Jan; Vol. 33 (1), pp. e4857.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*
Humans ; Peptide Hydrolases/genetics ; Cysteine Endopeptidases/chemistry ; Cysteine Endopeptidases/genetics ; Mutation ; Antiviral Agents/chemistry
Czasopismo naukowe
Tytuł:
LncRNA FRMD6-AS1 promotes hepatocellular carcinoma cell migration and stemness by regulating SENP1/HIF-1α axis.
Autorzy:
Sun W; The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China.
Lei X; School of Basic Medical Sciences and Forensic Medicine, Hangzhou Medical College, Hangzhou 310053, China.
Lu Q; Qingdao medical college, Qingdao university, Qingdao 266000, China.
Wu Q; The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China.
Ma Q; College of Bioscience Engineering, Zhejiang University of Technology, Hangzhou 310014, China.
Huang D; The Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, No. 8, Yikang Street, Lin'an District, Hangzhou 310014, China. Electronic address: .
Zhang Y; The Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, No. 8, Yikang Street, Lin'an District, Hangzhou 310014, China. Electronic address: .
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Źródło:
Pathology, research and practice [Pathol Res Pract] 2023 Mar; Vol. 243, pp. 154377. Date of Electronic Publication: 2023 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Cysteine Endopeptidases*/genetics
Cysteine Endopeptidases*/metabolism
Liver Neoplasms*/pathology
MicroRNAs*/genetics
RNA, Long Noncoding*/genetics
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Cytoskeletal Proteins/metabolism ; Gene Expression Regulation, Neoplastic ; Hypoxia ; Peptide Hydrolases/genetics ; Peptide Hydrolases/metabolism ; RNA, Messenger
Czasopismo naukowe
Tytuł:
Asparaginyl endopeptidase contributes to cetuximab resistance via MEK/ERK signaling in RAS wide-type metastatic colorectal cancer.
Autorzy:
Xu X; Department of Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Liu M; Department of Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Peng K; Department of Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yu Y; Department of Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Liu T; Department of Oncology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. .; Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. .; Center of Evidence-Based Medicine, Fudan University, 180 Feng Lin Road, Shanghai, 200032, China. .
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Źródło:
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2023 Mar; Vol. 25 (3), pp. 776-785. Date of Electronic Publication: 2023 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Drug Resistance, Neoplasm*/genetics
Cysteine Endopeptidases*/genetics
Cysteine Endopeptidases*/metabolism
Humans ; Cetuximab/pharmacology ; Cetuximab/therapeutic use ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/genetics ; ErbB Receptors/genetics ; Mitogen-Activated Protein Kinase Kinases/metabolism ; Mutation ; Proto-Oncogene Proteins p21(ras)/genetics ; Rectal Neoplasms/drug therapy ; Rectal Neoplasms/genetics ; Signal Transduction ; MAP Kinase Signaling System
Czasopismo naukowe

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