Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Cytidine Deaminase"" wg kryterium: Temat


Tytuł:
A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome.
Autorzy:
Della Mina E; Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, Australia.
Jackson KJL; Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.
Crawford AJI; Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.
Faulks ML; Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.
Pathmanandavel K; Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, Australia.
Acquarola N; Department of Clinical Immunology and PathWest, Fiona Stanley Hospital, Murdoch, WA, Australia.
O'Sullivan M; Department of Clinical Immunology and PathWest, Fiona Stanley Hospital, Murdoch, WA, Australia.; Department of Immunology, Perth Children's Hospital, Perth, WA, Australia.
Kerre T; Department of Hematology, Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.; Center for Primary Immunodeficiency Ghent (CPIG), Jeffrey Modell Diagnosis and Research Center, ERN Rita Network Center, Ghent University Hospital, Ghent, Belgium.
Naesens L; Center for Primary Immunodeficiency Ghent (CPIG), Jeffrey Modell Diagnosis and Research Center, ERN Rita Network Center, Ghent University Hospital, Ghent, Belgium.; Primary Immunodeficiency Research Lab, Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Claes K; Center for Primary Immunodeficiency Ghent (CPIG), Jeffrey Modell Diagnosis and Research Center, ERN Rita Network Center, Ghent University Hospital, Ghent, Belgium.; Primary Immunodeficiency Research Lab, Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Goodnow CC; Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, Australia.
Haerynck F; Center for Primary Immunodeficiency Ghent (CPIG), Jeffrey Modell Diagnosis and Research Center, ERN Rita Network Center, Ghent University Hospital, Ghent, Belgium.; Primary Immunodeficiency Research Lab, Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Kracker S; Laboratory of Human Lymphohematopoiesis, INSERM UMR 1163, Imagine Institute, 75015, Paris, France.; Université Paris Cité, 75015, Paris, France.
Meyts I; Inborn Errors of Immunity, Department of Microbiology, Immunology and Transplantation, KU Leuven, Louvain, Belgium.; Pediatric Immunodeficiency, Department of Pediatrics, University Hospitals Leuven, Louvain, Belgium.
D'Orsogna LJ; Department of Clinical Immunology and PathWest, Fiona Stanley Hospital, Murdoch, WA, Australia.; School of Medicine, University of Western Australia, Nedlands, WA, Australia.
Ma CS; Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, Australia.
Tangye SG; Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia. .; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, Australia. .
Pokaż więcej
Źródło:
Journal of clinical immunology [J Clin Immunol] 2024 Feb 16; Vol. 44 (3), pp. 66. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cytidine Deaminase*/genetics
Cytidine Deaminase*/metabolism
Hyper-IgM Immunodeficiency Syndrome*/genetics
Immunoglobulin Class Switching*/genetics
Humans ; Immunoglobulin A/genetics ; Immunoglobulin G/genetics ; Phenotype ; Somatic Hypermutation, Immunoglobulin
Czasopismo naukowe
Tytuł:
Compact zinc finger architecture utilizing toxin-derived cytidine deaminases for highly efficient base editing in human cells.
Autorzy:
Fauser F; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Kadam BN; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Arangundy-Franklin S; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Davis JE; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Vaidya V; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Schmidt NJ; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Lew G; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Xia DF; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Mureli R; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Ng C; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Zhou Y; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Scarlott NA; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Eshleman J; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Bendaña YR; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Shivak DA; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Reik A; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Li P; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Davis GD; Sangamo Therapeutics, Inc., Brisbane, CA, USA.
Miller JC; Sangamo Therapeutics, Inc., Brisbane, CA, USA. .
Pokaż więcej
Źródło:
Nature communications [Nat Commun] 2024 Feb 15; Vol. 15 (1), pp. 1181. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Editing*
Cytidine Deaminase*/genetics
Cytidine Deaminase*/metabolism
Humans ; DNA/metabolism ; Zinc Fingers ; Cytidine/genetics ; CRISPR-Cas Systems
Czasopismo naukowe
Tytuł:
Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors.
Autorzy:
Berríos KN; Graduate Group in Biochemistry and Molecular Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Barka A; Graduate Group in Biochemistry and Molecular Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Gill J; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Serrano JC; Graduate Group in Biochemistry and Molecular Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Bailer PF; Graduate Group in Biochemistry and Molecular Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Parker JB; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Evitt NH; Graduate Group in Cell and Molecular Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Gajula KS; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Shi J; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Kohli RM; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Pokaż więcej
Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Feb 28; Vol. 52 (4), pp. 2078-2090.
Typ publikacji:
Journal Article
MeSH Terms:
CRISPR-Associated Protein 9*/metabolism
Cytidine Deaminase*/metabolism
Escherichia coli*/metabolism
Gene Editing*
CRISPR-Cas Systems ; DNA/genetics ; Mutation ; RNA, Guide, CRISPR-Cas Systems ; Humans ; Animals
Czasopismo naukowe
Tytuł:
Identification of significant m6A regulators and immune microenvironment characterization in ischemic stroke.
Autorzy:
Zhao L; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China.
Song D; Department of Thoracic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Li T; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China.
Li Y; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China.
Dang M; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China.
Hao Q; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, Shaanxi, China.
Fan H; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China.
Lu Z; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China.
Lu J; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China.
Heyingwang; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China.
Wang X; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China.
Jian Y; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China.
Zhang G; Department of Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwulu, Xi'an, 710004, China. zhgl_.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2024 Feb 11; Vol. 14 (1), pp. 3456. Date of Electronic Publication: 2024 Feb 11.
Typ publikacji:
Journal Article
MeSH Terms:
Ischemic Stroke*/genetics
Cytidine Deaminase*
Proteins*
Adenine/*analogs & derivatives
Humans ; Biomarkers ; Tumor Microenvironment ; Methyltransferases
Czasopismo naukowe
Tytuł:
Stage II oesophageal carcinoma: peril in disguise associated with cellular reprogramming and oncogenesis regulated by pseudogenes.
Autorzy:
Pravallika G; Quantitative Biology Lab, Department of Integrative Biology, School of BioSciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
Rajasekaran R; Quantitative Biology Lab, Department of Integrative Biology, School of BioSciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, India. .
Pokaż więcej
Źródło:
BMC genomics [BMC Genomics] 2024 Feb 02; Vol. 25 (1), pp. 135. Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Esophageal Neoplasms*/genetics
Carcinoma*/genetics
Cytidine Deaminase*
Proteins*
Humans ; Pseudogenes ; Bayes Theorem ; Carcinogenesis/genetics ; Cellular Reprogramming ; Homeodomain Proteins/genetics
Czasopismo naukowe
Tytuł:
Improvement of C-to-U RNA editing using an artificial MS2-APOBEC system.
Autorzy:
Li J; Bioscience, Biotechnology and Biomedical Engineering Research Area, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa, Japan.
Fan G; Bioscience, Biotechnology and Biomedical Engineering Research Area, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa, Japan.; School of Medicine, Shaoxing University, Shaoxing, China.
Sakari M; Bioscience, Biotechnology and Biomedical Engineering Research Area, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa, Japan.
Tsukahara T; Bioscience, Biotechnology and Biomedical Engineering Research Area, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa, Japan.; GeCoRT Co. Ltd., Nishi-ku, Yokohama, Japan.
Pokaż więcej
Źródło:
Biotechnology journal [Biotechnol J] 2024 Jan; Vol. 19 (1), pp. e2300321. Date of Electronic Publication: 2023 Dec 05.
Typ publikacji:
Journal Article
MeSH Terms:
RNA Editing*/genetics
RNA, Guide, CRISPR-Cas Systems*
Cytidine Deaminase*
Proteins/metabolism ; RNA
Czasopismo naukowe
Tytuł:
Enhanced single-base mutation diversity by the combination of cytidine deaminase with DNA-repairing enzymes in yeast.
Autorzy:
Huang ZR; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.; Frontiers Research Institute for Synthetic Biology, Tianjin University, Tianjin, China.
Chen XR; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.; Frontiers Research Institute for Synthetic Biology, Tianjin University, Tianjin, China.
Liu DF; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.; Frontiers Research Institute for Synthetic Biology, Tianjin University, Tianjin, China.
Cui YZ; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.; Frontiers Research Institute for Synthetic Biology, Tianjin University, Tianjin, China.
Li BZ; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.; Frontiers Research Institute for Synthetic Biology, Tianjin University, Tianjin, China.
Yuan YJ; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.; Frontiers Research Institute for Synthetic Biology, Tianjin University, Tianjin, China.
Pokaż więcej
Źródło:
Biotechnology journal [Biotechnol J] 2023 Nov; Vol. 18 (11), pp. e2300137. Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:
Journal Article
MeSH Terms:
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Cytidine Deaminase*/genetics
Cytidine Deaminase*/metabolism
Mutation ; Mutagenesis ; DNA
Czasopismo naukowe
Tytuł:
Mayaro virus infection elicits a robust pro-inflammatory and antiviral response in human macrophages.
Autorzy:
Hernández-Sarmiento LJ; Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia.
Tamayo-Molina YS; Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia.
Valdés-López JF; Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia.
Urcuqui-Inchima S; Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia. Electronic address: .
Pokaż więcej
Źródło:
Acta tropica [Acta Trop] 2024 Apr; Vol. 252, pp. 107146. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-27*/metabolism
Interleukin-27*/pharmacology
Alphavirus*
Alphavirus Infections*
Cytidine Deaminase*
Proteins*
Humans ; Macrophages ; Interferons ; Antiviral Agents/pharmacology
Czasopismo naukowe
Tytuł:
Unraveling the Enzyme-Substrate Properties for APOBEC3A-Mediated RNA Editing.
Autorzy:
Kim K; Molecular and Computational Biology Program, Departments of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: https://twitter.com/KYUMINK1324.
Shi AB; Molecular and Computational Biology Program, Departments of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Kelley K; Molecular and Computational Biology Program, Departments of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Chen XS; Molecular and Computational Biology Program, Departments of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA; Genetic, Molecular and Cellular Biology Program, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA; Center of Excellence in NanoBiophysics, University of Southern California, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: .
Pokaż więcej
Źródło:
Journal of molecular biology [J Mol Biol] 2023 Sep 01; Vol. 435 (17), pp. 168198. Date of Electronic Publication: 2023 Jul 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cytidine Deaminase*/chemistry
Cytidine Deaminase*/genetics
Cytidine Deaminase*/metabolism
Proteins*/chemistry
Proteins*/genetics
Proteins*/metabolism
RNA Editing*
Humans ; Base Sequence ; HEK293 Cells ; Nucleic Acid Conformation ; RNA/chemistry ; Substrate Specificity
Czasopismo naukowe
Tytuł:
The off-target effects of AID in carcinogenesis.
Autorzy:
Jiao J; School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, China.
Lv Z; School of Forensic Medicine, Xinxiang Medical University, Xinxiang, Henan, China.
Wang Y; School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, China.
Fan L; School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, China.
Yang A; Henan Key Laboratory of Immunology and Targeted Therapy, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, Henan, China.; The State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, Shaanxi, China.; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, Henan, China.
Pokaż więcej
Źródło:
Frontiers in immunology [Front Immunol] 2023 Aug 04; Vol. 14, pp. 1221528. Date of Electronic Publication: 2023 Aug 04 (Print Publication: 2023).
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Autoimmune Diseases*
Hematologic Neoplasms*
Cytidine Deaminase*
Humans ; Carcinogenesis ; Cell Transformation, Neoplastic/genetics
Czasopismo naukowe
Tytuł:
Therapy-induced APOBEC3A drives evolution of persistent cancer cells.
Autorzy:
Isozaki H; Massachusetts General Hospital Cancer Center, Boston, MA, USA. .; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. .
Sakhtemani R; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Abbasi A; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Nikpour N; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Stanzione M; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Oh S; Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, School of Medicine, University of California Irvine, Irvine, CA, USA.
Langenbucher A; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Monroe S; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Su W; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Cabanos HF; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Siddiqui FM; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Phan N; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Jalili P; Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, School of Medicine, University of California Irvine, Irvine, CA, USA.
Timonina D; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Bilton S; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Gomez-Caraballo M; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Archibald HL; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Nangia V; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Dionne K; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Riley A; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Lawlor M; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Banwait MK; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Cobb RG; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
Zou L; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA.
Dyson NJ; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Ott CJ; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Benes C; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Getz G; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.
Chan CS; Department of Medicine, Rutgers Robert Wood Johnson Medical School and Center for Systems and Computational Biology, Rutgers Cancer Institute, New Brunswick, NJ, USA.
Shaw AT; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Gainor JF; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Lin JJ; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Sequist LV; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Piotrowska Z; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Yeap BY; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Engelman JA; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Lee JJ; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Maruvka YE; Faculty of Biotechnology and Food Engineering, Lorey Loki Center for Life Science and Engineering, Technion, Haifa, Israel.
Buisson R; Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, School of Medicine, University of California Irvine, Irvine, CA, USA.; Department of Pharmaceutical Sciences, School of Pharmacy & Pharmaceutical Sciences, University of California Irvine, Irvine, CA, USA.
Lawrence MS; Massachusetts General Hospital Cancer Center, Boston, MA, USA. .; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. .; Broad Institute of MIT and Harvard, Cambridge, MA, USA. .
Hata AN; Massachusetts General Hospital Cancer Center, Boston, MA, USA. .; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. .
Pokaż więcej
Źródło:
Nature [Nature] 2023 Aug; Vol. 620 (7973), pp. 393-401. Date of Electronic Publication: 2023 Jul 05.
Typ publikacji:
Journal Article
MeSH Terms:
Cytidine Deaminase*/deficiency
Cytidine Deaminase*/drug effects
Cytidine Deaminase*/genetics
Cytidine Deaminase*/metabolism
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Humans ; DNA Breaks, Double-Stranded ; Genomic Instability ; Molecular Targeted Therapy ; Mutation ; Drug Resistance, Neoplasm
Czasopismo naukowe
Tytuł:
Mitochondrial double-stranded RNA triggers induction of the antiviral DNA deaminase APOBEC3A and nuclear DNA damage.
Autorzy:
Wick C; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
Moghadasi SA; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
Becker JT; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
Fanunza E; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, USA; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.
Oh S; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Bournique E; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Buisson R; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Harris RS; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, USA; Howard Hughes Medical Institute, University of Texas Health San Antonio, San Antonio, Texas, USA. Electronic address: .
Pokaż więcej
Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Sep; Vol. 299 (9), pp. 105073. Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
DNA Damage*
Neoplasms*/genetics
RNA, Double-Stranded*/genetics
Cytidine Deaminase*/genetics
Humans ; DNA ; RNA, Mitochondrial/genetics
Czasopismo naukowe
Tytuł:
Genetic Variants in the Mitochondrial Thymidylate Biosynthesis Pathway Increase Colorectal Cancer Risk.
Autorzy:
Arrait EM; Biochemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Al-Ghafari AB; Biochemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 22252, Saudi Arabia.; Cancer and Mutagenesis Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 22252, Saudi Arabia.
Al Doghaither HA; Biochemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Pokaż więcej
Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2023 Aug 30; Vol. 30 (9), pp. 8039-8053. Date of Electronic Publication: 2023 Aug 30.
Typ publikacji:
Journal Article
MeSH Terms:
Cytidine Deaminase*
Colorectal Neoplasms*/genetics
Humans ; Case-Control Studies ; Heterozygote ; Capecitabine
Czasopismo naukowe
Tytuł:
Optimal AID expression and efficient immunoglobulin class switch recombination are dependent on the hypoxia-inducible factor.
Autorzy:
Heyer V; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), Illkirch, France.; Centre National de la Recherche Scientifique (CNRS), Illkirch, France.; Université de Strasbourg, Illkirch, France.
Reina-San-Martin B; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), Illkirch, France.; Centre National de la Recherche Scientifique (CNRS), Illkirch, France.; Université de Strasbourg, Illkirch, France.
Pokaż więcej
Źródło:
European journal of immunology [Eur J Immunol] 2023 Jul; Vol. 53 (7), pp. e2350373. Date of Electronic Publication: 2023 May 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytidine Deaminase*/metabolism
Gene Expression Regulation*
Animals ; Mice ; B-Lymphocytes ; Immunoglobulin Class Switching ; Immunoglobulin Isotypes/metabolism ; Somatic Hypermutation, Immunoglobulin ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł:
Mesoscale DNA feature in antibody-coding sequence facilitates somatic hypermutation.
Autorzy:
Wang Y; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China; Shanghai Institute of Immunology, Department of Immunology and Microbiology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Zhang S; Department of Mathematics, Shanghai Normal University, Shanghai 200234, China.
Yang X; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Hwang JK; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Zhan C; Shanghai Institute of Immunology, Department of Immunology and Microbiology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Lian C; Shanghai Institute of Immunology, Department of Immunology and Microbiology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Wang C; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Gui T; Shanghai Institute of Immunology, Department of Immunology and Microbiology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Wang B; Shanghai Institute of Immunology, Department of Immunology and Microbiology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Xie X; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
Dai P; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
Zhang L; School of Life Sciences, Fudan University, Shanghai 200438, China.
Tian Y; Shanghai Institute of Immunology, Department of Immunology and Microbiology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Zhang H; Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Han C; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
Cai Y; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
Hao Q; Shanghai Institute of Immunology, Department of Immunology and Microbiology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Ye X; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, 141-83 Stockholm, Sweden; Kindstar Global Precision Medicine Institute, Wuhan 430000, China.
Liu X; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
Liu J; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
Cao Z; School of Life Sciences, Fudan University, Shanghai 200438, China.
Huang S; Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; School of Biosciences, University of Chinese Academy of Sciences, Beijing 101499, China.
Song J; Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.
Pan-Hammarström Q; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, 141-83 Stockholm, Sweden; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Zhao Y; State Key Laboratory of Farm Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Alt FW; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Zheng X; Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Da LT; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Yeap LS; Shanghai Institute of Immunology, Department of Immunology and Microbiology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Endocrinology and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: .
Meng FL; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China; Shanghai Huashen Institute of Microbes and Infections, Shanghai 200052, China. Electronic address: .
Pokaż więcej
Źródło:
Cell [Cell] 2023 May 11; Vol. 186 (10), pp. 2193-2207.e19. Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytidine Deaminase*/genetics
Cytidine Deaminase*/metabolism
Somatic Hypermutation, Immunoglobulin*
Animals ; Mice ; Antibodies/genetics ; DNA/genetics ; DNA, Single-Stranded ; Mutation ; Evolution, Molecular ; Complementarity Determining Regions/genetics ; Nucleotide Motifs
Czasopismo naukowe
Tytuł:
B cell-specific knockout of AID protects against atherosclerosis.
Autorzy:
Ebrahimian T; Lady Davis Institute for Medical Research, 3755, Cote Ste Catherine, Montreal, QC, H3T 1E2, Canada. .
Dierick F; Lady Davis Institute for Medical Research, 3755, Cote Ste Catherine, Montreal, QC, H3T 1E2, Canada.
Ta V; Lady Davis Institute for Medical Research, 3755, Cote Ste Catherine, Montreal, QC, H3T 1E2, Canada.
Kotsiopriftis M; Lady Davis Institute for Medical Research, 3755, Cote Ste Catherine, Montreal, QC, H3T 1E2, Canada.
O'Connor Miranda J; Lady Davis Institute for Medical Research, 3755, Cote Ste Catherine, Montreal, QC, H3T 1E2, Canada.
Mann KK; Lady Davis Institute for Medical Research, 3755, Cote Ste Catherine, Montreal, QC, H3T 1E2, Canada.
Orthwein A; Lady Davis Institute for Medical Research, 3755, Cote Ste Catherine, Montreal, QC, H3T 1E2, Canada.
Lehoux S; Lady Davis Institute for Medical Research, 3755, Cote Ste Catherine, Montreal, QC, H3T 1E2, Canada. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2023 May 30; Vol. 13 (1), pp. 8723. Date of Electronic Publication: 2023 May 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis*/genetics
Atherosclerosis*/prevention & control
Atherosclerosis*/metabolism
Plaque, Atherosclerotic*/genetics
Plaque, Atherosclerotic*/metabolism
Cytidine Deaminase*/genetics
Animals ; Mice ; B-Lymphocytes ; Cell Differentiation ; Hydrolases/metabolism ; Immunoglobulin M/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, LDL/genetics ; Receptors, LDL/metabolism
Czasopismo naukowe
Tytuł:
A computational exploration of global and temporal dynamics of selection pressure on HIV-1 Vif polymorphism.
Autorzy:
Arman MS; Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet 3114, Bangladesh.
Hasan MZ; Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet 3114, Bangladesh. Electronic address: .
Pokaż więcej
Źródło:
Virus research [Virus Res] 2024 Mar; Vol. 341, pp. 199323. Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*
HIV Infections*
Humans ; vif Gene Products, Human Immunodeficiency Virus/genetics ; vif Gene Products, Human Immunodeficiency Virus/chemistry ; vif Gene Products, Human Immunodeficiency Virus/metabolism ; Mutation, Missense ; Polymorphism, Genetic ; Protein Binding ; Cytidine Deaminase/genetics ; Cytidine Deaminase/metabolism
Czasopismo naukowe
Tytuł:
HIV-1 Vif protein sequence variations in South African people living with HIV and their influence on Vif-APOBEC3G interaction.
Autorzy:
Williams ME; Human Metabolomics, North-West University, Potchefstroom, South Africa. .
Pokaż więcej
Źródło:
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 2024 Feb; Vol. 43 (2), pp. 325-338. Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*/genetics
HIV-1*/metabolism
HIV Infections*
Humans ; vif Gene Products, Human Immunodeficiency Virus/genetics ; vif Gene Products, Human Immunodeficiency Virus/metabolism ; Cytidine Deaminase/genetics ; Cytidine Deaminase/metabolism ; African People ; APOBEC-3G Deaminase/genetics
Czasopismo naukowe
Tytuł:
RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork.
Autorzy:
Hayran AB; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.
Liabakk NB; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.
Aas PA; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.
Kusnierczyk A; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; PROMEC - Proteomics and Modomics Experimental Core Facility at NTNU and the Central Norway Regional Health Authority, NO-7491 Trondheim, Norway.
Vågbø CB; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; PROMEC - Proteomics and Modomics Experimental Core Facility at NTNU and the Central Norway Regional Health Authority, NO-7491 Trondheim, Norway.
Sarno A; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.
Iveland TS; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; Cancer Clinic, St. Olav's Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.
Chawla K; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; BioCore - Bioinformatics Core Facility at NTNU and the Central Norway Regional Health Authority, NO-7491 Trondheim, Norway.
Zahn A; Institut de Recherches Cliniques de Montréal, 110 Av des Pins Ouest, Montréal, QC H2W 1R7, Canada.
Di Noia JM; Institut de Recherches Cliniques de Montréal, 110 Av des Pins Ouest, Montréal, QC H2W 1R7, Canada.; Département of Médicine, Université de Montréal H3C 3J7 Montréal, Québec, Canada.
Slupphaug G; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; PROMEC - Proteomics and Modomics Experimental Core Facility at NTNU and the Central Norway Regional Health Authority, NO-7491 Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olav's Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.
Kavli B; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olav's Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.
Pokaż więcej
Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Jan 25; Vol. 52 (2), pp. 784-800.
Typ publikacji:
Journal Article
MeSH Terms:
Replication Protein A*/genetics
Replication Protein A*/metabolism
Uracil-DNA Glycosidase*/genetics
Uracil-DNA Glycosidase*/metabolism
Cytidine Deaminase/genetics ; Cytidine Deaminase/metabolism ; DNA Repair/genetics ; DNA, Single-Stranded/genetics ; Immunoglobulin Class Switching/genetics ; Immunoglobulin Isotypes/genetics ; Immunoglobulins/genetics ; Mutagens ; Uracil/metabolism ; Humans ; Animals ; Mice
Czasopismo naukowe
Tytuł:
APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability.
Autorzy:
Kawale AS; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
Ran X; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA.
Patel PS; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
Saxena S; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
Lawrence MS; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
Zou L; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.
Pokaż więcej
Źródło:
Science advances [Sci Adv] 2024 Jan 19; Vol. 10 (3), pp. eadk2771. Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Poly(ADP-ribose) Polymerase Inhibitors*
Proteins*/metabolism
DNA ; Cytidine Deaminase/genetics ; Cytidine Deaminase/metabolism ; DNA Replication ; DNA, Single-Stranded/genetics
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies