- Tytuł:
- Understanding CYP3A4 and P-gp mediated drug-drug interactions through PBPK modeling - Case example of pralsetinib.
- Autorzy:
- Źródło:
- CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Apr; Vol. 13 (4), pp. 660-672. Date of Electronic Publication: 2024 Mar 13.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Cytochrome P-450 CYP3A */metabolism
Pyrimidines*
Pyrazoles*
Humans ; Drug Interactions ; Pyridines ; Membrane Transport Proteins ;Cytochrome P-450 CYP3A Inhibitors/pharmacology ; Models, Biological
Czasopismo naukowe