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Wyszukujesz frazę ""Cytochrome P-450 CYP3A"" wg kryterium: Temat

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Wyświetlanie 1-20 z 49
Tytuł:
The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC.
Autorzy:
Liptrott NJ; Department of Pharmacology and Therapeutics, The University of Liverpool, UK. />Penny M
Bray PG
Sathish J
Khoo SH
Back DJ
Owen A
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2009 Feb; Vol. 156 (3), pp. 497-508. Date of Electronic Publication: 2009 Jan 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Aryl Hydrocarbon Hydroxylases/*metabolism
Carrier Proteins/*metabolism
Cytochrome P-450 CYP3A/*metabolism
Cytokines/*pharmacology
Leukocytes, Mononuclear/*drug effects
Oxidoreductases, N-Demethylating/*metabolism
Aryl Hydrocarbon Hydroxylases/antagonists & inhibitors ; Aryl Hydrocarbon Hydroxylases/genetics ; Biological Transport ; Cells, Cultured ; Cytochrome P-450 CYP2B6 ; Cytochrome P-450 CYP3A/genetics ; Cytochrome P-450 CYP3A Inhibitors ; Cytokines/physiology ; Digoxin/pharmacokinetics ; Flow Cytometry ; Humans ; Leukocytes, Mononuclear/enzymology ; Leukocytes, Mononuclear/metabolism ; Multidrug Resistance-Associated Protein 2 ; Oxidoreductases, N-Demethylating/antagonists & inhibitors ; Oxidoreductases, N-Demethylating/genetics ; Receptors, Chemokine/biosynthesis ; Reverse Transcriptase Polymerase Chain Reaction ; Saquinavir/pharmacokinetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Different effects of proton pump inhibitors and famotidine on the clopidogrel metabolic activation by recombinant CYP2B6, CYP2C19 and CYP3A4.
Autorzy:
Ohbuchi M; Drug Metabolism Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Osaka, Japan. />Noguchi K
Kawamura A
Usui T
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Źródło:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2012 Jul; Vol. 42 (7), pp. 633-40. Date of Electronic Publication: 2012 Feb 07.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Aryl Hydrocarbon Hydroxylases/*metabolism
Cytochrome P-450 CYP3A/*metabolism
Famotidine/*pharmacology
Oxidoreductases, N-Demethylating/*metabolism
Proton Pump Inhibitors/*pharmacology
Ticlopidine/*analogs & derivatives
Aryl Hydrocarbon Hydroxylases/genetics ; Biotransformation ; Clopidogrel ; Cytochrome P-450 CYP2B6 ; Cytochrome P-450 CYP2C19 ; Cytochrome P-450 CYP3A/genetics ; Drug Interactions ; Humans ; Oxidoreductases, N-Demethylating/genetics ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Ticlopidine/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pharmacologic evidence to support clinical decision making for peripartum methadone treatment.
Autorzy:
Bogen DL; Department of Pediatrics, Division of General Academic Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, 3414 Fifth Ave, CHOB 3rd floor, Pittsburgh, PA 15213, USA. />Perel JM
Helsel JC
Hanusa BH
Romkes M
Nukui T
Friedman CR
Wisner KL
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2013 Jan; Vol. 225 (2), pp. 441-51. Date of Electronic Publication: 2012 Aug 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Aryl Hydrocarbon Hydroxylases/*genetics
Methadone/*administration & dosage
Opioid-Related Disorders/*rehabilitation
Oxidoreductases, N-Demethylating/*genetics
Pregnancy Complications/*drug therapy
Adolescent ; Adult ; Cytochrome P-450 CYP2B6 ; Cytochrome P-450 CYP2C19 ; Cytochrome P-450 CYP3A/genetics ; Decision Making ; Dose-Response Relationship, Drug ; Female ; Genotype ; Half-Life ; Humans ; Longitudinal Studies ; Opiate Substitution Treatment/methods ; Peripartum Period ; Polymorphism, Single Nucleotide ; Pregnancy ; Pregnancy Trimester, Third ; Prospective Studies ; Stereoisomerism ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study.
Autorzy:
Yimer G; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Amogne W
Habtewold A
Makonnen E
Ueda N
Suda A
Worku A
Haefeli WE
Burhenne J
Aderaye G
Lindquist L
Aklillu E
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Źródło:
The pharmacogenomics journal [Pharmacogenomics J] 2012 Dec; Vol. 12 (6), pp. 499-506. Date of Electronic Publication: 2011 Aug 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiretroviral Therapy, Highly Active/*adverse effects
Aryl Hydrocarbon Hydroxylases/*genetics
Benzoxazines/*adverse effects
Chemical and Drug Induced Liver Injury/*genetics
HIV Infections/*drug therapy
Oxidoreductases, N-Demethylating/*genetics
ATP Binding Cassette Transporter, Subfamily B ; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics ; Adult ; Alkynes ; Benzoxazines/blood ; Cohort Studies ; Cyclopropanes ; Cytochrome P-450 CYP2B6 ; Cytochrome P-450 CYP3A/genetics ; Female ; Genotype ; Humans ; Male ; Proportional Hazards Models ; Prospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Pharmacogenetics of toxicity, plasma trough concentration and treatment outcome with nevirapine-containing regimen in anti-retroviral-naïve HIV-infected adults: an exploratory study of the TRIANON ANRS 081 trial.
Autorzy:
Gozalo C; Department of Molecular Genetics, Pharmacogenetics and Hormonology, Assistance Publique-Hôpitaux de Paris, Bicêtre Hospital, France.
Gérard L
Loiseau P
Morand-Joubert L
Peytavin G
Molina JM
Dellamonica P
Becquemont L
Aboulker JP
Launay O
Verstuyft C
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Corporate Authors:
ANRS 081 Study Group
Źródło:
Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2011 Dec; Vol. 109 (6), pp. 513-20. Date of Electronic Publication: 2011 Sep 06.
Typ publikacji:
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Anti-HIV Agents*/blood
Anti-HIV Agents*/therapeutic use
Anti-HIV Agents*/toxicity
Nevirapine*/blood
Nevirapine*/therapeutic use
Nevirapine*/toxicity
Polymorphism, Single Nucleotide*
Aryl Hydrocarbon Hydroxylases/*genetics
HIV Infections/*drug therapy
Oxidoreductases, N-Demethylating/*genetics
ATP Binding Cassette Transporter, Subfamily B ; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics ; Adult ; Antiretroviral Therapy, Highly Active ; CD4 Lymphocyte Count ; Cytochrome P-450 CYP2B6 ; Cytochrome P-450 CYP3A/genetics ; Female ; HIV Infections/blood ; HIV Infections/enzymology ; HIV Infections/virology ; HLA-DRB1 Chains/genetics ; Humans ; Kaplan-Meier Estimate ; Male ; Pharmacogenetics ; Treatment Outcome ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Stereoselectivity in metabolism of ifosfamide by CYP3A4 and CYP2B6.
Autorzy:
Lu H; College of Pharmacy, Comprehensive Cancer Center, Ohio State University, Columbus, OH, USA. />Wang JJ
Chan KK
Philip PA
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Źródło:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2006 May; Vol. 36 (5), pp. 367-85.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents, Alkylating/*pharmacokinetics
Aryl Hydrocarbon Hydroxylases/*metabolism
Cytochrome P-450 Enzyme System/*metabolism
Ifosfamide/*pharmacokinetics
Microsomes, Liver/*enzymology
Oxidoreductases, N-Demethylating/*metabolism
Animals ; Antineoplastic Agents, Alkylating/pharmacology ; Biotransformation ; Cell Line ; Cytochrome P-450 CYP2B6 ; Cytochrome P-450 CYP3A ; Humans ; Ifosfamide/pharmacology ; Male ; Rats ; Rats, Sprague-Dawley ; Stereoisomerism ; Substrate Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cytochrome P450 3A and 2B6 in the developing kidney: implications for ifosfamide nephrotoxicity.
Autorzy:
Aleksa K; Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.
Matsell D
Krausz K
Gelboin H
Ito S
Koren G
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Źródło:
Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2005 Jul; Vol. 20 (7), pp. 872-85. Date of Electronic Publication: 2005 May 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aging/*metabolism
Aryl Hydrocarbon Hydroxylases/*metabolism
Kidney/*embryology
Kidney/*enzymology
Oxidoreductases, N-Demethylating/*metabolism
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Monoclonal/pharmacology ; Antineoplastic Agents, Alkylating/adverse effects ; Antineoplastic Agents, Alkylating/metabolism ; Aryl Hydrocarbon Hydroxylases/immunology ; Blotting, Western ; Child ; Child, Preschool ; Cyclophosphamide/analogs & derivatives ; Cyclophosphamide/chemistry ; Cyclophosphamide/metabolism ; Cytochrome P-450 CYP2B6 ; Cytochrome P-450 CYP3A ; Fetus/enzymology ; Humans ; Ifosfamide/adverse effects ; Ifosfamide/analogs & derivatives ; Ifosfamide/chemistry ; Ifosfamide/metabolism ; Immunohistochemistry ; Infant ; Kidney/drug effects ; Kidney/metabolism ; Microsomes/enzymology ; Microsomes/metabolism ; Middle Aged ; Oxidoreductases, N-Demethylating/immunology ; Stereoisomerism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Model systems based on experimental animals for studies on drug metabolism in man: (mini)pig cytochromes P450 3A29 and 2E1.
Autorzy:
Anzenbacherová E; Institute of Medical Chemistry and Biochemistry, Faculty of Medicine, Palacky University, Hnevotinska 3, CZ-775 15 Olomouc, Czech Republic. />Baranová J
Zuber R
Pechová A
Anzenbacher P
Soucek P
Martínková J
Pokaż więcej
Źródło:
Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2005 Mar; Vol. 96 (3), pp. 244-5.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aryl Hydrocarbon Hydroxylases/*physiology
Cytochrome P-450 CYP2E1/*physiology
Nifedipine/*metabolism
Oxidoreductases, N-Demethylating/*physiology
Testosterone/*metabolism
Animals ; Cytochrome P-450 CYP3A ; Humans ; Models, Biological ; Swine ; Swine, Miniature
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Ethnic differences between Japanese and Caucasians in the expression levels of mRNAs for CYP3A4, CYP3A5 and CYP3A7: lack of co-regulation of the expression of CYP3A in Japanese livers.
Autorzy:
Yamaori S; Laboratory of Drug Metabolism, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. />Yamazaki H
Iwano S
Kiyotani K
Matsumura K
Saito T
Parkinson A
Nakagawa K
Kamataki T
Pokaż więcej
Źródło:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2005 Jan; Vol. 35 (1), pp. 69-83.
Typ publikacji:
Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aryl Hydrocarbon Hydroxylases/*metabolism
Cytochrome P-450 Enzyme System/*metabolism
Liver/*enzymology
Oxidoreductases, N-Demethylating/*metabolism
RNA, Messenger/*genetics
RNA, Messenger/*metabolism
Reverse Transcriptase Polymerase Chain Reaction/*methods
Aryl Hydrocarbon Hydroxylases/genetics ; Asian People/genetics ; Computer Systems ; Cytochrome P-450 CYP3A ; Cytochrome P-450 Enzyme System/genetics ; Gene Expression Regulation, Enzymologic/physiology ; Genetic Testing/methods ; Humans ; Oxidoreductases, N-Demethylating/genetics ; White People/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Melatonin attenuates lipopolysaccharide-induced down-regulation of pregnane X receptor and its target gene CYP3A in mouse liver.
Autorzy:
Xu DX; Institute of Clinical Pharmacology, Anhui Medical University, Hefei, P.R. China. />Wei W
Sun MF
Wei LZ
Wang JP
Pokaż więcej
Źródło:
Journal of pineal research [J Pineal Res] 2005 Jan; Vol. 38 (1), pp. 27-34.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aryl Hydrocarbon Hydroxylases/*metabolism
Down-Regulation/*physiology
Lipopolysaccharides/*pharmacology
Melatonin/*physiology
Microsomes, Liver/*drug effects
Oxidoreductases, N-Demethylating/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Receptors, Steroid/*metabolism
Animals ; Aryl Hydrocarbon Hydroxylases/genetics ; Base Sequence ; Cytochrome P-450 CYP3A ; DNA Primers ; Down-Regulation/drug effects ; Female ; Glutathione/metabolism ; Membrane Proteins ; Mice ; Mice, Inbred ICR ; Microsomes, Liver/enzymology ; Microsomes, Liver/metabolism ; Oxidoreductases, N-Demethylating/genetics ; Pregnane X Receptor ; RNA, Messenger/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Role of CYP3A enzymes in the biotransformation of triazolam in rat liver.
Autorzy:
Warrington JS; Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA, USA.
Greenblatt DJ
Von Moltke LL
Pokaż więcej
Źródło:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2004 May; Vol. 34 (5), pp. 463-71.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Aryl Hydrocarbon Hydroxylases/*metabolism
Microsomes, Liver/*metabolism
Oxidoreductases, N-Demethylating/*metabolism
Triazolam/*metabolism
Adult ; Animals ; Aryl Hydrocarbon Hydroxylases/antagonists & inhibitors ; Biotransformation ; Cytochrome P-450 CYP3A ; Enzyme Inhibitors/pharmacology ; GABA-A Receptor Agonists ; Humans ; Hydroxylation ; In Vitro Techniques ; Isoenzymes/metabolism ; Ketoconazole/pharmacology ; Kinetics ; Male ; Microsomes, Liver/drug effects ; Oxidoreductases, N-Demethylating/antagonists & inhibitors ; Rats ; Rats, Inbred F344 ; Recombinant Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Model for the drug-drug interaction responsible for CYP3A enzyme inhibition. II: establishment and evaluation of dexamethasone-pretreated female rats.
Autorzy:
Kanazu T; Developmental Research Laboratories, Shionogi & Co., LTD, Toyonaka, Osaka, Japan. />Yamaguchi Y
Okamura N
Baba T
Koike M
Pokaż więcej
Źródło:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2004 May; Vol. 34 (5), pp. 403-13.
Typ publikacji:
Comparative Study; Evaluation Study; Journal Article
MeSH Terms:
Aryl Hydrocarbon Hydroxylases/*antagonists & inhibitors
Dexamethasone/*administration & dosage
Oxidoreductases, N-Demethylating/*antagonists & inhibitors
Administration, Oral ; Animals ; Cytochrome P-450 CYP3A ; Drug Interactions ; Enzyme Inhibitors/administration & dosage ; Female ; Humans ; In Vitro Techniques ; Ketoconazole/administration & dosage ; Kinetics ; Microsomes, Liver/drug effects ; Microsomes, Liver/enzymology ; Midazolam/administration & dosage ; Midazolam/metabolism ; Midazolam/pharmacokinetics ; Models, Animal ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes.
Autorzy:
Schmidt R; Institute of Clinical Pharmacology, University of Leipzig, Härtelstr. 16-18, D-04107 Leipzig, Germany. />Baumann F
Knüpfer H
Brauckhoff M
Horn LC
Schönfelder M
Köhler U
Preiss R
Pokaż więcej
Źródło:
British journal of cancer [Br J Cancer] 2004 Feb 23; Vol. 90 (4), pp. 911-6.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents, Alkylating/*metabolism
Antineoplastic Agents, Alkylating/*pharmacokinetics
Aryl Hydrocarbon Hydroxylases/*biosynthesis
Breast Neoplasms/*genetics
Breast Neoplasms/*pathology
Cytochrome P-450 Enzyme System/*biosynthesis
Ifosfamide/*metabolism
Ifosfamide/*pharmacokinetics
Oxidoreductases, N-Demethylating/*biosynthesis
Aged ; Aged, 80 and over ; Breast Neoplasms/surgery ; Cytochrome P-450 CYP2B6 ; Cytochrome P-450 CYP2C9 ; Cytochrome P-450 CYP3A ; Female ; Humans ; Microsomes ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Ritonavir and dexamethasone induce expression of CYP3A and P-glycoprotein in rats.
Autorzy:
Perloff MD; Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, and the Division of Clinical Pharmacology, Tufts-New England Medical Center, Boston, MA 02111, USA.
von Moltke LL
Greenblatt DJ
Pokaż więcej
Źródło:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2004 Feb; Vol. 34 (2), pp. 133-50.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
ATP Binding Cassette Transporter, Subfamily B, Member 1/*biosynthesis
Anti-Inflammatory Agents/*pharmacology
Aryl Hydrocarbon Hydroxylases/*biosynthesis
Dexamethasone/*pharmacology
HIV Protease Inhibitors/*pharmacology
Oxidoreductases, N-Demethylating/*biosynthesis
Ritonavir/*pharmacology
ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics ; Algorithms ; Animals ; Antibodies, Blocking/pharmacology ; Aryl Hydrocarbon Hydroxylases/antagonists & inhibitors ; Aryl Hydrocarbon Hydroxylases/genetics ; Blood-Brain Barrier/drug effects ; Blotting, Western ; Capillaries/drug effects ; Capillaries/enzymology ; Chromatography, High Pressure Liquid ; Cytochrome P-450 CYP3A ; Enzyme Induction/drug effects ; Enzyme Inhibitors/pharmacology ; GABA Modulators/metabolism ; Gene Expression/drug effects ; Intestines/drug effects ; Intestines/enzymology ; Liver/drug effects ; Liver/enzymology ; Luminescent Measurements ; Male ; Microsomes/drug effects ; Microsomes/enzymology ; Oxidoreductases, N-Demethylating/antagonists & inhibitors ; Oxidoreductases, N-Demethylating/genetics ; Rats ; Rats, Sprague-Dawley ; Triazolam/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.
Autorzy:
Anakk S; Department of Biochemistry & Molecular Biology, The University of Texas Medical School of Houston, TX 77225, USA.
Kalsotra A
Kikuta Y
Huang W
Zhang J
Staudinger JL
Moore DD
Strobel HW
Pokaż więcej
Źródło:
The pharmacogenomics journal [Pharmacogenomics J] 2004; Vol. 4 (2), pp. 91-101.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Aryl Hydrocarbon Hydroxylases/*genetics
Cytochrome P-450 Enzyme System/*genetics
Oxidoreductases/*genetics
Oxidoreductases, N-Demethylating/*genetics
Receptors, Cytoplasmic and Nuclear/*physiology
Receptors, Steroid/*physiology
Transcription Factors/*physiology
Animals ; Aryl Hydrocarbon Hydroxylases/biosynthesis ; Constitutive Androstane Receptor ; Cytochrome P-450 CYP3A ; Cytochrome P-450 Enzyme System/biosynthesis ; Dexamethasone/pharmacology ; Dose-Response Relationship, Drug ; Female ; Gene Expression Regulation, Enzymologic/drug effects ; Gene Expression Regulation, Enzymologic/physiology ; Isoenzymes/biosynthesis ; Isoenzymes/genetics ; Isoenzymes/physiology ; Male ; Membrane Proteins ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microsomes, Liver/drug effects ; Microsomes, Liver/enzymology ; Oxidoreductases/biosynthesis ; Oxidoreductases, N-Demethylating/biosynthesis ; Pregnane X Receptor ; Receptors, Cytoplasmic and Nuclear/biosynthesis ; Receptors, Cytoplasmic and Nuclear/deficiency ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, Steroid/biosynthesis ; Receptors, Steroid/deficiency ; Receptors, Steroid/genetics ; Transcription Factors/deficiency ; Transcription Factors/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Physiological regulation of P-glycoprotein, MRP1, MRP2 and cytochrome P450 3A2 during rat ontogeny.
Autorzy:
Rosati A; Department of Biomedical Sciences, University of Trieste, Via L. Giorgieri no. 7, 34100 Trieste, Italy.
Maniori S
Decorti G
Candussio L
Giraldi T
Bartoli F
Pokaż więcej
Źródło:
Development, growth & differentiation [Dev Growth Differ] 2003 Aug; Vol. 45 (4), pp. 377-87.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP-Binding Cassette Transporters*
ATP Binding Cassette Transporter, Subfamily B, Member 1/*metabolism
Aryl Hydrocarbon Hydroxylases/*metabolism
Carrier Proteins/*metabolism
Embryo, Mammalian/*metabolism
Oxidoreductases, N-Demethylating/*metabolism
Aging ; Animals ; Cytochrome P-450 CYP3A ; Liver/enzymology ; Liver/metabolism ; Organ Specificity ; Rats ; Rats, Wistar ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 49

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