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Tytuł :
Suppressors of cytokine signaling (SOCS) proteins in inflammatory bone disorders.
Autorzy :
Santos MRG; Department of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Queiroz-Junior CM; Department of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Madeira MFM; Department of Microbiology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
Machado FS; Department of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil; Program in Health Sciences: Infectious Diseases and Tropical Medicine/Interdisciplinary Laboratory of Medical Investigation, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
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Źródło :
Bone [Bone] 2020 Nov; Vol. 140, pp. 115538. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Bone Diseases*
Signal Transduction*
Suppressor of Cytokine Signaling Proteins*/metabolism
Animals ; Cytokines ; Humans ; Osteoclasts/metabolism ; Suppressor of Cytokine Signaling 1 Protein ; Suppressor of Cytokine Signaling 3 Protein
Czasopismo naukowe
Tytuł :
Immune Responses to the Novel Coronavirus-2: Friend or Foe?
Autorzy :
Mahmoodpoor A; Professor of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Nader ND; Professor of Anesthesiology and Surgery, University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, USA.
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Źródło :
Immunological investigations [Immunol Invest] 2021 Nov; Vol. 50 (8), pp. 949-951. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji :
Letter
MeSH Terms :
Immunity*
COVID-19/*diagnosis
Cytokine Release Syndrome/*immunology
Respiratory Distress Syndrome/*immunology
SARS-CoV-2/*immunology
COVID-19/complications ; COVID-19/immunology ; COVID-19/virology ; Cytokine Release Syndrome/epidemiology ; Cytokine Release Syndrome/pathology ; Cytokine Release Syndrome/virology ; Humans ; Lung/immunology ; Lung/pathology ; Lung/virology ; Respiratory Distress Syndrome/epidemiology ; Respiratory Distress Syndrome/virology ; Respiratory Mucosa/immunology ; Respiratory Mucosa/pathology ; Respiratory Mucosa/virology ; Severity of Illness Index
Opinia redakcyjna
Tytuł :
Successful Treatment of Covid-19 Associated Cytokine Release Syndrome with Colchicine. A Case Report and Review of Literature.
Autorzy :
Mansouri N; Division of Pulmonary Medicine, Department of Medicine, Lausanne University Hospital (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland.; Department of Clinical Immunology and Infectious Diseases, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Marjani M; The Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Tabarsi P; The Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
von Garnier C; Division of Pulmonary Medicine, Department of Medicine, Lausanne University Hospital (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland.
Mansouri D; Department of Clinical Immunology and Infectious Diseases, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; The Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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Źródło :
Immunological investigations [Immunol Invest] 2021 Nov; Vol. 50 (8), pp. 884-890. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
COVID-19/*drug therapy
Colchicine/*administration & dosage
Cytokine Release Syndrome/*drug therapy
Gout/*drug therapy
Administration, Oral ; Adult ; COVID-19/complications ; COVID-19/immunology ; COVID-19/virology ; Cytokine Release Syndrome/diagnosis ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/virology ; Gout/diagnosis ; Gout/immunology ; Gout/virology ; Humans ; Male ; SARS-CoV-2/immunology ; Treatment Outcome
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Interindividual immunogenic variants: Susceptibility to coronavirus, respiratory syncytial virus and influenza virus.
Autorzy :
Darbeheshti F; Department of Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Medical Genetics Network (MeGeNe), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Mahdiannasser M; Department of Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Uhal BD; Department of Physiology, Michigan State University, East Lansing, Michigan, USA.
Ogino S; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Cancer Immunology and Cancer Epidemiology Programs, Dana-Farber Harvard Cancer Center, Boston, Massachusetts, USA.
Gupta S; Division of Basic and Clinical Immunology, Department of Medicine, University of California, Irvine, California, USA.
Rezaei N; Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
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Źródło :
Reviews in medical virology [Rev Med Virol] 2021 Nov; Vol. 31 (6), pp. e2234. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genetic Predisposition to Disease*
COVID-19/*immunology
Cytokine Release Syndrome/*immunology
Influenza, Human/*immunology
Respiratory Syncytial Virus Infections/*immunology
Severe Acute Respiratory Syndrome/*immunology
Antiviral Agents/therapeutic use ; Biological Variation, Individual ; COVID-19/drug therapy ; COVID-19/genetics ; COVID-19/virology ; Cytokine Release Syndrome/drug therapy ; Cytokine Release Syndrome/genetics ; Cytokine Release Syndrome/virology ; Gene Expression ; Humans ; Immunity, Innate ; Immunologic Factors/therapeutic use ; Influenza, Human/drug therapy ; Influenza, Human/genetics ; Influenza, Human/virology ; Mannose-Binding Lectin/genetics ; Mannose-Binding Lectin/immunology ; Orthomyxoviridae/drug effects ; Orthomyxoviridae/immunology ; Respiratory Syncytial Virus Infections/drug therapy ; Respiratory Syncytial Virus Infections/genetics ; Respiratory Syncytial Virus Infections/virology ; Respiratory Syncytial Viruses/drug effects ; Respiratory Syncytial Viruses/immunology ; SARS Virus/drug effects ; SARS Virus/immunology ; SARS-CoV-2/classification ; SARS-CoV-2/drug effects ; SARS-CoV-2/immunology ; Severe Acute Respiratory Syndrome/drug therapy ; Severe Acute Respiratory Syndrome/genetics ; Severe Acute Respiratory Syndrome/virology ; Toll-Like Receptors/genetics ; Toll-Like Receptors/immunology
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Interleukin-17A (IL-17A): A silent amplifier of COVID-19.
Autorzy :
Maione F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Casillo GM; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Raucci F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Salvatore C; New.Fa.DEm SRL, Viale Ferrovie Dello Stato, 1, 80014 Giugliano in Campania, Naples, Italy.
Ambrosini G; New.Fa.DEm SRL, Viale Ferrovie Dello Stato, 1, 80014 Giugliano in Campania, Naples, Italy.
Costa L; Department of Clinical Medicine and Surgery, School of Medicine and Surgery, University of Naples Federico II, Via Sergio Pansini, 5, 80131 Naples, Italy.
Scarpa R; Department of Clinical Medicine and Surgery, School of Medicine and Surgery, University of Naples Federico II, Via Sergio Pansini, 5, 80131 Naples, Italy.
Caso F; Department of Clinical Medicine and Surgery, School of Medicine and Surgery, University of Naples Federico II, Via Sergio Pansini, 5, 80131 Naples, Italy. Electronic address: .
Bucci M; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Oct; Vol. 142, pp. 111980. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/diagnosis
COVID-19*/drug therapy
COVID-19*/immunology
Cytokine Release Syndrome*/etiology
Cytokine Release Syndrome*/immunology
Interleukin-17*/blood
Interleukin-17*/immunology
Biomarkers/blood ; Disease Progression ; Drug Discovery ; Humans ; Inflammation Mediators/metabolism ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Induction of Exaggerated Cytokine Production in Human Peripheral Blood Mononuclear Cells by a Recombinant SARS-CoV-2 Spike Glycoprotein S1 and Its Inhibition by Dexamethasone.
Autorzy :
Olajide OA; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK. .
Iwuanyanwu VU; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK.
Lepiarz-Raba I; BRAINCITY-EMBL-Nencki Center of Excellence for Neuronal Plasticity and Brain Disorders, Nencki Institute of Experimental Biology, Warsaw, Poland.
Al-Hindawi AA; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK.
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Źródło :
Inflammation [Inflammation] 2021 Oct; Vol. 44 (5), pp. 1865-1877. Date of Electronic Publication: 2021 Apr 16.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Cytokine Release Syndrome/*virology
Cytokines/*metabolism
Dexamethasone/*pharmacology
Leukocytes, Mononuclear/*metabolism
SARS-CoV-2/*pathogenicity
Spike Glycoprotein, Coronavirus/*immunology
Anti-Inflammatory Agents/therapeutic use ; Biomarkers/metabolism ; Blotting, Western ; COVID-19/drug therapy ; COVID-19/immunology ; COVID-19/virology ; Cells, Cultured ; Cytokine Release Syndrome/drug therapy ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/metabolism ; Dexamethasone/therapeutic use ; Enzyme-Linked Immunosorbent Assay ; Humans ; Leukocytes, Mononuclear/drug effects ; Recombinant Proteins/immunology ; SARS-CoV-2/immunology
Czasopismo naukowe
Tytuł :
Impact of vitamin D on the course of COVID-19 during pregnancy: A case control study.
Autorzy :
Sinaci S; Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey. Electronic address: .
Ocal DF; Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Yucel Yetiskin DF; Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Uyan Hendem D; Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Buyuk GN; Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Goncu Ayhan S; Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Tanacan A; Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Ozgu-Erdinc AS; Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Moraloglu Tekin O; Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey; University of Health Sciences, Ankara City Hospital, Ankara, Turkey.
Sahin D; Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey; University of Health Sciences, Ankara City Hospital, Ankara, Turkey.
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Źródło :
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2021 Oct; Vol. 213, pp. 105964. Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article
MeSH Terms :
Dietary Supplements*
COVID-19/*diet therapy
Cytokine Release Syndrome/*diet therapy
Pregnancy Complications, Infectious/*diet therapy
Vitamin D/*administration & dosage
Vitamin D Deficiency/*diet therapy
Adult ; COVID-19/blood ; COVID-19/pathology ; COVID-19/virology ; Calcifediol/blood ; Case-Control Studies ; Cytokine Release Syndrome/blood ; Cytokine Release Syndrome/pathology ; Cytokine Release Syndrome/virology ; Female ; Gestational Age ; Humans ; Pregnancy ; Pregnancy Complications, Infectious/blood ; Pregnancy Complications, Infectious/pathology ; Pregnancy Complications, Infectious/virology ; SARS-CoV-2/pathogenicity ; Severity of Illness Index ; Treatment Outcome ; Vitamin D/analogs & derivatives ; Vitamin D/blood ; Vitamin D Deficiency/blood ; Vitamin D Deficiency/pathology ; Vitamin D Deficiency/virology
Czasopismo naukowe
Tytuł :
Can molecular mimicry explain the cytokine storm of SARS-CoV-2?: An in silico approach.
Autorzy :
Obando-Pereda G; Proteomics, Inflammation and Pain Laboratory, Universidad Católica de Santa María, Arequipa, Peru.
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Źródło :
Journal of medical virology [J Med Virol] 2021 Sep; Vol. 93 (9), pp. 5350-5357. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19/*immunology
Coronavirus Papain-Like Proteases/*chemistry
Cytokine Release Syndrome/*immunology
Neoplasm Proteins/*chemistry
Poly(ADP-ribose) Polymerases/*chemistry
SARS-CoV-2/*immunology
Amino Acid Sequence ; Binding Sites ; COVID-19/genetics ; COVID-19/pathology ; COVID-19/virology ; Computer Simulation ; Consensus Sequence ; Coronavirus Papain-Like Proteases/genetics ; Coronavirus Papain-Like Proteases/immunology ; Cytokine Release Syndrome/genetics ; Cytokine Release Syndrome/pathology ; Cytokine Release Syndrome/virology ; Epitopes/chemistry ; Epitopes/genetics ; Epitopes/immunology ; Gene Expression ; Histocompatibility Antigens Class I/chemistry ; Histocompatibility Antigens Class I/genetics ; Histocompatibility Antigens Class I/immunology ; Histocompatibility Antigens Class II/chemistry ; Histocompatibility Antigens Class II/genetics ; Histocompatibility Antigens Class II/immunology ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/immunology ; Humans ; Macrophages/immunology ; Macrophages/virology ; Molecular Docking Simulation ; Molecular Mimicry ; Neoplasm Proteins/genetics ; Neoplasm Proteins/immunology ; Poly(ADP-ribose) Polymerases/genetics ; Poly(ADP-ribose) Polymerases/immunology ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; SARS-CoV-2/genetics ; SARS-CoV-2/pathogenicity ; Sequence Alignment ; Sequence Homology, Amino Acid ; Thermodynamics
Czasopismo naukowe
Tytuł :
Colorectal cancer cell-derived extracellular vesicles transfer miR-221-3p to promote endothelial cell angiogenesis via targeting suppressor of cytokine signaling 3.
Autorzy :
Dokhanchi M; Department of Biology, Faculty of Sciences, Islamic Azad University, Tehran, Iran.
Pakravan K; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Zareian S; Department of Biology, Faculty of Sciences, Islamic Azad University, Tehran, Iran.
Hussen BM; Department of Pharmacognosy, College of Pharmacy, Hawler Medical University, Kurdistan Region, Iraq.
Farid M; Department of Biology, Faculty of Sciences, Islamic Azad University, Tehran, Iran.
Razmara E; Department of Medical Genetics, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Mossahebi-Mohammadi M; School of Pharmaceutical Sciences and International Collaborative Center on Growth Factor Research, Wenzhou Medical University, Wenzhou, China.
Cho WC; Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong. Electronic address: .
Babashah S; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Nov 15; Vol. 285, pp. 119937. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor/*metabolism
Colorectal Neoplasms/*blood supply
Colorectal Neoplasms/*pathology
MicroRNAs/*metabolism
Neovascularization, Pathologic/*metabolism
Suppressor of Cytokine Signaling 3 Protein/*metabolism
Biomarkers, Tumor/blood ; Cytokines/metabolism ; Extracellular Vesicles/metabolism ; HCT116 Cells ; Human Umbilical Vein Endothelial Cells ; Humans ; Lymphatic Metastasis ; MicroRNAs/blood ; Neovascularization, Pathologic/genetics ; STAT3 Transcription Factor/metabolism ; Suppressor of Cytokine Signaling 3 Protein/genetics
Czasopismo naukowe
Tytuł :
C-reactive protein as an effector molecule in Covid-19 pathogenesis.
Autorzy :
Mosquera-Sulbaran JA; Instituto de Investigaciones Clinicas 'Dr. Americo Negrette', Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela.
Pedreañez A; Catedra de Inmunologia, Escuela de Bioanalisis, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela.
Carrero Y; Facultad de Ciencias de la Salud, Carrera de Medicina, Universidad Tecnica de Ambato, Ambato, Ecuador.
Callejas D; Facultad de Ciencias de la Salud, Departamento de Ciencias Biologicas, Universidad Tecnica de Manabi, Portoviejo, Ecuador.
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Źródło :
Reviews in medical virology [Rev Med Virol] 2021 Nov; Vol. 31 (6), pp. e2221. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
C-Reactive Protein/*antagonists & inhibitors
COVID-19/*drug therapy
Complement System Proteins/*immunology
Cytokine Release Syndrome/*drug therapy
SARS-CoV-2/*pathogenicity
ADAM17 Protein/antagonists & inhibitors ; ADAM17 Protein/genetics ; ADAM17 Protein/immunology ; Angiotensin-Converting Enzyme 2/antagonists & inhibitors ; Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/immunology ; Biomarkers/blood ; C-Reactive Protein/genetics ; C-Reactive Protein/immunology ; COVID-19/immunology ; COVID-19/pathology ; COVID-19/virology ; Celecoxib/therapeutic use ; Complement System Proteins/genetics ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/pathology ; Cytokine Release Syndrome/virology ; Cytokines/antagonists & inhibitors ; Cytokines/genetics ; Cytokines/immunology ; Disease Progression ; Doxycycline/therapeutic use ; Gene Expression Regulation ; Humans ; Randomized Controlled Trials as Topic ; Severity of Illness Index ; Survival Analysis
Czasopismo naukowe
Tytuł :
Perforin, COVID-19 and a possible pathogenic auto-inflammatory feedback loop.
Autorzy :
Cunningham L; St. John's Institute of Dermatology, Guy's and St Thomas' Hospital, London, UK.
Kimber I; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Basketter D; DABMEB Consultancy Ltd, Wotton-under-Edge, UK.
Simmonds P; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
McSweeney S; St. John's Institute of Dermatology, Guy's and St Thomas' Hospital, London, UK.
Tziotzios C; St. John's Institute of Dermatology, Guy's and St Thomas' Hospital, London, UK.
McFadden JP; St. John's Institute of Dermatology, Guy's and St Thomas' Hospital, London, UK.
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Źródło :
Scandinavian journal of immunology [Scand J Immunol] 2021 Nov; Vol. 94 (5), pp. e13102. Date of Electronic Publication: 2021 Sep 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*immunology
Cytokine Release Syndrome/*immunology
Killer Cells, Natural/*immunology
Lymphohistiocytosis, Hemophagocytic/*immunology
Neutrophils/*immunology
Perforin/*metabolism
SARS-CoV-2/*physiology
Animals ; Autoimmunity/genetics ; COVID-19/epidemiology ; Cytokine Release Syndrome/epidemiology ; Disease Resistance ; Humans ; Interleukin-6/metabolism ; Lymphohistiocytosis, Hemophagocytic/epidemiology ; Perforin/genetics
Czasopismo naukowe
Tytuł :
Cytokine storm associated coagulation complications in COVID-19 patients: Pathogenesis and Management.
Autorzy :
Savla SR; Department of Pharmacology, Dr. Bhanuben Nanavati College of Pharmacy, Vile Parle (West), Mumbai, 400056, India.
Prabhavalkar KS; Department of Pharmacology, Dr. Bhanuben Nanavati College of Pharmacy, Vile Parle (West), Mumbai, 400056, India.
Bhatt LK; Department of Pharmacology, Dr. Bhanuben Nanavati College of Pharmacy, Vile Parle (West), Mumbai, 400056, India.
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Źródło :
Expert review of anti-infective therapy [Expert Rev Anti Infect Ther] 2021 Nov; Vol. 19 (11), pp. 1397-1413. Date of Electronic Publication: 2021 Apr 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Blood Coagulation Disorders*/drug therapy
Blood Coagulation Disorders*/virology
COVID-19*/complications
Cytokine Release Syndrome*/virology
Venous Thromboembolism*/drug therapy
Venous Thromboembolism*/virology
Heparin, Low-Molecular-Weight/therapeutic use ; Humans
Czasopismo naukowe
Tytuł :
Laboratory biomarkers and prognosis in Covid-19, where do we stand?
Autorzy :
Israni A; Imperial College School of Medicine, Faculty of Medicine, Imperial College London, London, UK.
Goulden CJ; Imperial College School of Medicine, Faculty of Medicine, Imperial College London, London, UK.
Harky A; Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK.; Institute of Integrative biology, Faculty of Health and Life Science, University of Liverpool, Liverpool, UK.
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Źródło :
Reviews in medical virology [Rev Med Virol] 2021 Nov; Vol. 31 (6), pp. e2296. Date of Electronic Publication: 2021 Sep 13.
Typ publikacji :
Editorial
MeSH Terms :
COVID-19/*diagnosis
Cytokine Release Syndrome/*diagnosis
Disseminated Intravascular Coagulation/*diagnosis
SARS-CoV-2/*pathogenicity
Aspartate Aminotransferases/blood ; Asymptomatic Diseases ; Biomarkers/blood ; C-Reactive Protein/metabolism ; COVID-19/drug therapy ; COVID-19/mortality ; COVID-19/pathology ; Creatine Kinase/blood ; Cytokine Release Syndrome/drug therapy ; Cytokine Release Syndrome/mortality ; Cytokine Release Syndrome/pathology ; Disseminated Intravascular Coagulation/drug therapy ; Disseminated Intravascular Coagulation/mortality ; Disseminated Intravascular Coagulation/pathology ; Fibrin Fibrinogen Degradation Products/metabolism ; Humans ; Interleukin-6/blood ; L-Lactate Dehydrogenase/blood ; Leukocytes/immunology ; Leukocytes/virology ; Lymphopenia/diagnosis ; Lymphopenia/pathology ; Lymphopenia/virology ; Prognosis ; Severity of Illness Index ; Survival Analysis ; Thrombocytopenia/diagnosis ; Thrombocytopenia/pathology ; Thrombocytopenia/virology
Opinia redakcyjna
Tytuł :
Conquering the cytokine storm in COVID-19-induced ARDS using placenta-derived decidua stromal cells.
Autorzy :
Sadeghi B; Translational Cell Therapy Research (TCR), Department of Clinical Science, Intervention and Technology, CLINTEC, Karolinska Institutet, Huddinge, Sweden.
Roshandel E; Hematopoietic Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pirsalehi A; Department of Internal Medicine, School of Medicine, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Kazemi S; Translational Cell Therapy Research (TCR), Department of Clinical Science, Intervention and Technology, CLINTEC, Karolinska Institutet, Huddinge, Sweden.; Advanced Therapy Medicinal Product (ATMP), Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran.
Sankanian G; Hematopoietic Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Majidi M; Department of Tissue Engineering & Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.
Salimi M; Hematopoietic Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Aghdami N; Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.; Department of Infectious Diseases and Tropical Medicines, Tehran University of Medical Sciences, Tehran, Iran.
Sadrosadat H; Advanced Therapy Medicinal Product (ATMP), Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran.
Samadi Kochaksaraei S; Translational Cell Therapy Research (TCR), Department of Clinical Science, Intervention and Technology, CLINTEC, Karolinska Institutet, Huddinge, Sweden.; Advanced Therapy Medicinal Product (ATMP), Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran.
Alaeddini F; Research Center for Health Management in Mass Gathering, Red Crescent Society of the Islamic Republic of Iran, Tehran, Iran.
Ringden O; Translational Cell Therapy Research (TCR), Department of Clinical Science, Intervention and Technology, CLINTEC, Karolinska Institutet, Huddinge, Sweden.
Hajifathali A; Hematopoietic Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2021 Nov; Vol. 25 (22), pp. 10554-10564. Date of Electronic Publication: 2021 Oct 10.
Typ publikacji :
Case Reports; Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*drug therapy
Cell Transplantation/*methods
Cytokine Release Syndrome/*therapy
Respiratory Distress Syndrome/*virology
Stromal Cells/*transplantation
Adolescent ; Adult ; Aged ; COVID-19/complications ; COVID-19/therapy ; Cell Transplantation/adverse effects ; Cytokine Release Syndrome/etiology ; Cytokines/blood ; Female ; Humans ; Length of Stay ; Male ; Middle Aged ; Placenta/cytology ; Pregnancy ; Respiratory Distress Syndrome/therapy ; Stromal Cells/physiology ; Treatment Outcome
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Signaling pathways in the regulation of cytokine release syndrome in human diseases and intervention therapy.
Autorzy :
Li X; Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, Hangzhou, 311121, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, Zhejiang, People's Republic of China.
Shao M; Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, Hangzhou, 311121, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, Zhejiang, People's Republic of China.
Zeng X; Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, Hangzhou, 311121, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, Zhejiang, People's Republic of China.
Qian P; Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China. .; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, Hangzhou, 311121, People's Republic of China. .; Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China. .; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, Zhejiang, People's Republic of China. .; Center of Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Hangzhou, People's Republic of China. .
Huang H; Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China. .; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, Hangzhou, 311121, People's Republic of China. .; Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China. .; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, Zhejiang, People's Republic of China. .
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Źródło :
Signal transduction and targeted therapy [Signal Transduct Target Ther] 2021 Oct 20; Vol. 6 (1), pp. 367. Date of Electronic Publication: 2021 Oct 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cytokine Release Syndrome*/etiology
Cytokine Release Syndrome*/immunology
Cytokine Release Syndrome*/therapy
Signal Transduction/*immunology
Acute Disease ; Autoimmune Diseases/complications ; Autoimmune Diseases/immunology ; Autoimmune Diseases/therapy ; COVID-19/complications ; COVID-19/immunology ; COVID-19/therapy ; Graft vs Host Disease/complications ; Graft vs Host Disease/immunology ; Graft vs Host Disease/therapy ; Hematopoietic Stem Cell Transplantation ; Humans ; Immunotherapy, Adoptive/adverse effects ; Influenza, Human/complications ; Influenza, Human/immunology ; Neoplasms/complications ; Neoplasms/immunology ; Neoplasms/therapy ; SARS Virus/immunology ; SARS-CoV-2/immunology ; Severe Acute Respiratory Syndrome/complications ; Severe Acute Respiratory Syndrome/immunology ; Severe Acute Respiratory Syndrome/therapy
Czasopismo naukowe
Tytuł :
Autoinflammatory Diseases and Cytokine Storms-Imbalances of Innate and Adaptative Immunity.
Autorzy :
Marcuzzi A; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Melloni E; LTTA Centre, Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Zauli G; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Romani A; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Secchiero P; LTTA Centre, Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Maximova N; Bone Marrow Transplant Unit, Institute for Maternal and Child Health-IRCCS Burlo Garofolo, 34137 Trieste, Italy.
Rimondi E; LTTA Centre, Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 18; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adaptive Immunity*
Immunity, Innate*
Autoimmune Diseases/*pathology
Cytokine Release Syndrome/*pathology
Autoimmune Diseases/immunology ; COVID-19/complications ; COVID-19/pathology ; COVID-19/virology ; Cytokine Release Syndrome/etiology ; Cytokine Release Syndrome/immunology ; Cytokines/metabolism ; Humans ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; SARS-CoV-2/isolation & purification
Czasopismo naukowe
Tytuł :
Role of Gut Microbiome in COVID-19: An Insight Into Pathogenesis and Therapeutic Potential.
Autorzy :
Hussain I; Department of Gastroenterology, Khoo Teck Puat Hospital, Singapore, Singapore.
Cher GLY; Department of Gastroenterology, Khoo Teck Puat Hospital, Singapore, Singapore.
Abid MA; Department of Hematopathology and Microbiology, Aga Khan University Hospital, Karachi, Pakistan.
Abid MB; Division of Infectious Diseases, Medical College of Wisconsin, Milwaukee, WI, United States.; Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Oct 14; Vol. 12, pp. 765965. Date of Electronic Publication: 2021 Oct 14 (Print Publication: 2021).
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*microbiology
Cytokine Release Syndrome/*microbiology
Dysbiosis/*microbiology
Gastrointestinal Microbiome/*immunology
SARS-CoV-2/*physiology
COVID-19/immunology ; Cytokine Release Syndrome/immunology ; Dysbiosis/immunology ; Humans ; Immunity ; Inflammation
Czasopismo naukowe
Tytuł :
Cyclic mimetics of kinase-inhibitory region of Suppressors of Cytokine Signaling 1: Progress toward novel anti-inflammatory therapeutics.
Autorzy :
La Manna S; Department of Pharmacy - University of Naples 'Federico II', 80134, Naples, Italy; Renal and Vascular Inflammation Group, Instituto de Investigacion Sanitaria-Fundacion Jimenez Diaz (IIS-FJD), Autonoma University of Madrid (UAM), 28040, Madrid, Spain.
Lopez-Sanz L; Renal and Vascular Inflammation Group, Instituto de Investigacion Sanitaria-Fundacion Jimenez Diaz (IIS-FJD), Autonoma University of Madrid (UAM), 28040, Madrid, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), 28040, Madrid, Spain.
Bernal S; Renal and Vascular Inflammation Group, Instituto de Investigacion Sanitaria-Fundacion Jimenez Diaz (IIS-FJD), Autonoma University of Madrid (UAM), 28040, Madrid, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), 28040, Madrid, Spain.
Fortuna S; Department of Chemical and Pharmaceutical Sciences, University of Trieste, 34127, Trieste, Italy.
Mercurio FA; Institute of Biostructures and Bioimaging - CNR, 80134, Naples, Italy.
Leone M; Institute of Biostructures and Bioimaging - CNR, 80134, Naples, Italy.
Gomez-Guerrero C; Renal and Vascular Inflammation Group, Instituto de Investigacion Sanitaria-Fundacion Jimenez Diaz (IIS-FJD), Autonoma University of Madrid (UAM), 28040, Madrid, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), 28040, Madrid, Spain.
Marasco D; Department of Pharmacy - University of Naples 'Federico II', 80134, Naples, Italy. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 05; Vol. 221, pp. 113547. Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Peptidomimetics/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Suppressor of Cytokine Signaling 1 Protein/*antagonists & inhibitors
Animals ; Anti-Inflammatory Agents/chemical synthesis ; Anti-Inflammatory Agents/chemistry ; Cells, Cultured ; Dose-Response Relationship, Drug ; Mice ; Molecular Structure ; Peptidomimetics/chemical synthesis ; Peptidomimetics/chemistry ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Structure-Activity Relationship ; Suppressor of Cytokine Signaling 1 Protein/metabolism
Czasopismo naukowe
Tytuł :
COVID-19 and male reproductive system: pathogenic features and possible mechanisms.
Autorzy :
Ardestani Zadeh A; Clinical Research Development Center, Kowsar Hospital, Semnan University of Medical Sciences, Semnan, Iran.; Department of Surgery, Kowsar Hospital, Semnan University of Medical Sciences, Semnan, Iran.
Arab D; Clinical Research Development Center, Kowsar Hospital, Semnan University of Medical Sciences, Semnan, Iran. .; Department of Surgery, Kowsar Hospital, Semnan University of Medical Sciences, Semnan, Iran. .
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Źródło :
Journal of molecular histology [J Mol Histol] 2021 Oct; Vol. 52 (5), pp. 869-878. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cytokine Release Syndrome*
COVID-19/*epidemiology
Infertility, Male/*pathology
SARS-CoV-2/*physiology
COVID-19/pathology ; Genitalia, Male/pathology ; Humans ; Male
Czasopismo naukowe
Tytuł :
Antibody response to SARS-CoV-2 in patients receiving glucocorticoids with or without tocilizumab for COVID-19-associated hyperinflammation.
Autorzy :
Janssen MTHF; Pulmonology, Zuyderland Medical Centre Heerlen, Heerlen, The Netherlands .
Ramiro S; Rheumatology, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands.; Rheumatology, Zuyderland Medical Centre Heerlen, Heerlen, Limburg, The Netherlands.
Landewé RBM; Rheumatology, Zuyderland Medical Centre Heerlen, Heerlen, Limburg, The Netherlands.; Amsterdam Rheumatology Center, AMC, Amsterdam, The Netherlands.
Magro-Checa C; Rheumatology, Zuyderland Medical Centre Heerlen, Heerlen, Limburg, The Netherlands.
Mostard RLM; Pulmonology, Zuyderland Medical Centre Heerlen, Heerlen, The Netherlands.
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Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2021 Oct; Vol. 80 (10), pp. 1362-1363. Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Letter
MeSH Terms :
Antibodies, Viral/*drug effects
COVID-19/*drug therapy
COVID-19/*immunology
Cytokine Release Syndrome/*drug therapy
Immunosuppressive Agents/*therapeutic use
Antibodies, Monoclonal, Humanized/therapeutic use ; Antibodies, Viral/blood ; Antibodies, Viral/immunology ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/virology ; Humans ; Methylprednisolone/therapeutic use ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Opinia redakcyjna

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