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Tytuł :
[Generation of Multiple Ocular Lineages from Human Pluripotent Stem Cells and Its Application to Regenerative Medicine].
Autorzy :
Hayashi R; Graduate School of Medicine, Osaka University.
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Źródło :
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan [Yakugaku Zasshi] 2021; Vol. 141 (1), pp. 55-60.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Epithelium, Corneal*/cytology
Epithelium, Corneal*/transplantation
Cell Differentiation/*physiology
Induced Pluripotent Stem Cells/*cytology
Induced Pluripotent Stem Cells/*physiology
Regenerative Medicine/*methods
Cell Lineage ; Cells, Cultured ; Corneal Diseases/therapy ; Humans ; Organoids ; Retinal Pigment Epithelium/cytology
Czasopismo naukowe
Tytuł :
Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids.
Autorzy :
van den Brink SC; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands. .
Alemany A; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands.
van Batenburg V; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands.
Moris N; Department of Genetics, University of Cambridge, Cambridge, UK.
Blotenburg M; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands.
Vivié J; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands.
Baillie-Johnson P; Department of Genetics, University of Cambridge, Cambridge, UK.
Nichols J; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Sonnen KF; Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands.
Martinez Arias A; Department of Genetics, University of Cambridge, Cambridge, UK.
van Oudenaarden A; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands. .
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Źródło :
Nature [Nature] 2020 Jun; Vol. 582 (7812), pp. 405-409. Date of Electronic Publication: 2020 Feb 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gastrula*/cytology
Gastrula*/embryology
Gastrula*/metabolism
Single-Cell Analysis*
Transcriptome*
Mouse Embryonic Stem Cells/*cytology
Organoids/*cytology
Organoids/*embryology
Somites/*cytology
Somites/*embryology
Animals ; Collagen ; Drug Combinations ; Embryo, Mammalian/cytology ; Embryo, Mammalian/embryology ; Embryo, Mammalian/metabolism ; Embryonic Development ; Female ; Gene Expression Regulation, Developmental ; Laminin ; Male ; Mice ; Mouse Embryonic Stem Cells/metabolism ; Organoids/metabolism ; Proteoglycans ; RNA-Seq ; Somites/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Single-cell analyses and machine learning define hematopoietic progenitor and HSC-like cells derived from human PSCs.
Autorzy :
Fidanza A; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Stumpf PS; Joint Research Center for Computational Biomedicine, Uniklinik Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Ramachandran P; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Tamagno S; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Babtie A; Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College London, London, United Kingdom; and.
Lopez-Yrigoyen M; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Taylor AH; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Easterbrook J; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Henderson BEP; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Axton R; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Henderson NC; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Medvinsky A; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Ottersbach K; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Romanò N; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Forrester LM; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
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Źródło :
Blood [Blood] 2020 Dec 17; Vol. 136 (25), pp. 2893-2904.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Differentiation*/biosynthesis
Antigens, Differentiation*/genetics
Hematopoietic Stem Cells*/cytology
Hematopoietic Stem Cells*/metabolism
Machine Learning*
Pluripotent Stem Cells*/cytology
Pluripotent Stem Cells*/metabolism
RNA-Seq*
Single-Cell Analysis*
Fetus/cytology ; Fetus/metabolism ; Gene Expression Regulation ; Humans ; Liver/cytology ; Liver/metabolism
Czasopismo naukowe
Tytuł :
Nuclear exclusion of YAP exacerbates podocyte apoptosis and disease progression in Adriamycin-induced focal segmental glomerulosclerosis.
Autorzy :
Zhuang Q; Department of Pathology, School of Basic Medical Sciences, Fudan University, Shanghai, China.; Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Li F; Department of Pathology, School of Basic Medical Sciences, Fudan University, Shanghai, China.; Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.
Liu J; Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang H; Department of Pathology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Tian Y; Department of Pathology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Zhang Z; Department of Pathology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Wang F; Department of Nephrology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Zhao Z; Department of Pathology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Chen J; Division of Nephrology in Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA. .
Wu H; Department of Pathology, School of Basic Medical Sciences, Fudan University, Shanghai, China. .
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Źródło :
Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2021 Feb; Vol. 101 (2), pp. 258-270. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Glomerulosclerosis, Focal Segmental*/genetics
Glomerulosclerosis, Focal Segmental*/metabolism
Glomerulosclerosis, Focal Segmental*/pathology
Podocytes*/cytology
Podocytes*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Apoptosis/*genetics
Animals ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cell Nucleus/metabolism ; Cells, Cultured ; Disease Models, Animal ; Disease Progression ; Doxorubicin/adverse effects ; Humans ; Kidney/cytology ; Kidney/metabolism ; Kidney/pathology ; Male ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Concentration and total number of circulating primordial germ cells in Green-legged Partridgelike chicken embryos.
Autorzy :
Szczerba A; Department of Animal Biotechnology and Genetics, Faculty of Animal Breeding and Biology, University of Science and Technology in Bydgoszcz, 85-084 Bydgoszcz, Poland. Electronic address: .
Kuwana T; Department of Animal Biotechnology and Genetics, Faculty of Animal Breeding and Biology, University of Science and Technology in Bydgoszcz, 85-084 Bydgoszcz, Poland.
Bednarczyk M; Department of Animal Biotechnology and Genetics, Faculty of Animal Breeding and Biology, University of Science and Technology in Bydgoszcz, 85-084 Bydgoszcz, Poland.
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Źródło :
Poultry science [Poult Sci] 2021 Jan; Vol. 100 (1), pp. 319-324. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Chickens*/blood
Germ Cells*/cytology
Animals ; Blood Cells ; Cell Count/veterinary ; Chick Embryo ; Embryonic Development ; Gonads/cytology
Czasopismo naukowe
Tytuł :
Stimulation of neural stem cell differentiation by circularly polarized light transduced by chiral nanoassemblies.
Autorzy :
Qu A; Key Laboratory of Synthetic and Biological Colloids, International Joint Research Laboratory for Biointerface and Biodetection, Jiangnan University, Wuxi, Jiangsu, China.; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Sun M; Key Laboratory of Synthetic and Biological Colloids, International Joint Research Laboratory for Biointerface and Biodetection, Jiangnan University, Wuxi, Jiangsu, China.; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Kim JY; Department of Chemical Engineering, Biointerface Institute, University of Michigan, Ann Arbor, MI, USA.
Xu L; Key Laboratory of Synthetic and Biological Colloids, International Joint Research Laboratory for Biointerface and Biodetection, Jiangnan University, Wuxi, Jiangsu, China.; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Hao C; Key Laboratory of Synthetic and Biological Colloids, International Joint Research Laboratory for Biointerface and Biodetection, Jiangnan University, Wuxi, Jiangsu, China.; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Ma W; Key Laboratory of Synthetic and Biological Colloids, International Joint Research Laboratory for Biointerface and Biodetection, Jiangnan University, Wuxi, Jiangsu, China.; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Wu X; Key Laboratory of Synthetic and Biological Colloids, International Joint Research Laboratory for Biointerface and Biodetection, Jiangnan University, Wuxi, Jiangsu, China.; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Liu X; Department of Chemistry, Faculty of Science, National University of Singapore, Singapore, Singapore.
Kuang H; Key Laboratory of Synthetic and Biological Colloids, International Joint Research Laboratory for Biointerface and Biodetection, Jiangnan University, Wuxi, Jiangsu, China. .; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China. .
Kotov NA; Department of Chemical Engineering, Biointerface Institute, University of Michigan, Ann Arbor, MI, USA. .
Xu C; Key Laboratory of Synthetic and Biological Colloids, International Joint Research Laboratory for Biointerface and Biodetection, Jiangnan University, Wuxi, Jiangsu, China. .; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China. .
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Źródło :
Nature biomedical engineering [Nat Biomed Eng] 2021 Jan; Vol. 5 (1), pp. 103-113. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Differentiation*/drug effects
Cell Differentiation*/radiation effects
Neural Stem Cells*/cytology
Neural Stem Cells*/drug effects
Neural Stem Cells*/radiation effects
Metal Nanoparticles/*chemistry
Nanostructures/*chemistry
Animals ; Cell Culture Techniques ; Cells, Cultured ; Cytoskeleton/drug effects ; Cytoskeleton/metabolism ; Cytoskeleton/radiation effects ; DNA/chemistry ; Gold/chemistry ; Hippocampus/cytology ; Humans ; Mice ; Mice, Transgenic ; Recombinant Fusion Proteins ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Intraovarian injection of mesenchymal stem cells improves oocyte yield and in vitro embryo production in a bovine model of fertility loss.
Autorzy :
Malard PF; Universidade Católica de Brasília, Brasília, DF, 70790-160, Brazil. .; Bio Biotecnologia da Reprodução Animal, Brasília, DF, 71735-505, Brazil. .
Peixer MAS; Universidade Católica de Brasília, Brasília, DF, 70790-160, Brazil.; Bio Biotecnologia da Reprodução Animal, Brasília, DF, 71735-505, Brazil.
Grazia JG; Cenatte Embrioes, Pedro Leopoldo, MG, 33600-000, Brazil.
Brunel HDSS; Bio Biotecnologia da Reprodução Animal, Brasília, DF, 71735-505, Brazil.
Feres LF; Universidade de Alfenas, Alfenas, MG, 37132-440, Brazil.
Villarroel CL; Bio Biotecnologia da Reprodução Animal, Brasília, DF, 71735-505, Brazil.
Siqueira LGB; Empresa Brasileira de Pesquisa Agropecuária - EMBRAPA Gado de Leite, Juiz de Fora, MG, 36038-330, Brazil.
Dode MAN; Empresa Brasileira de Pesquisa Agropecuária - EMBRAPA Recursos Genéticos e Biotecnologia, Brasília, DF, 70770-917, Brazil.
Pogue R; Universidade Católica de Brasília, Brasília, DF, 70790-160, Brazil.
Viana JHM; Empresa Brasileira de Pesquisa Agropecuária - EMBRAPA Recursos Genéticos e Biotecnologia, Brasília, DF, 70770-917, Brazil.
Carvalho JL; Universidade Católica de Brasília, Brasília, DF, 70790-160, Brazil. .; Universidade de Brasília, Brasília, DF, 70910-900, Brazil. .
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Źródło :
Scientific reports [Sci Rep] 2020 May 15; Vol. 10 (1), pp. 8018. Date of Electronic Publication: 2020 May 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Embryonic Development*
Mesenchymal Stem Cell Transplantation*
Mesenchymal Stem Cells*/cytology
Mesenchymal Stem Cells*/metabolism
Oocytes/*physiology
Ovary/*cytology
Ovary/*physiology
Animals ; Biomarkers ; Blastocyst/cytology ; Cattle ; Cell Differentiation ; Embryo Culture Techniques ; Embryo, Mammalian ; Female ; Fertilization in Vitro ; Gene Expression Profiling ; Infertility, Female/etiology ; Infertility, Female/therapy
Czasopismo naukowe
Tytuł :
Reprogramming to recover youthful epigenetic information and restore vision.
Autorzy :
Lu Y; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Brommer B; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Tian X; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Krishnan A; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Schepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School, Boston, MA, USA.
Meer M; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
Wang C; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Vera DL; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Zeng Q; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Yu D; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Bonkowski MS; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Yang JH; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Zhou S; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Hoffmann EM; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Schepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School, Boston, MA, USA.
Karg MM; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Schepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School, Boston, MA, USA.
Schultz MB; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Kane AE; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Davidsohn N; Department of Genetics, Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
Korobkina E; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Schepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School, Boston, MA, USA.
Chwalek K; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Rajman LA; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA.
Church GM; Department of Genetics, Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
Hochedlinger K; Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Gladyshev VN; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Horvath S; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Levine ME; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
Gregory-Ksander MS; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Schepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School, Boston, MA, USA.
Ksander BR; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Schepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School, Boston, MA, USA.
He Z; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Sinclair DA; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, MA, USA. .; Laboratory for Ageing Research, Department of Pharmacology, School of Medical Sciences, The University of New South Wales, Sydney, New South Wales, Australia. .
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Źródło :
Nature [Nature] 2020 Dec; Vol. 588 (7836), pp. 124-129. Date of Electronic Publication: 2020 Dec 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA Methylation*
Epigenesis, Genetic*
Eye*/cytology
Eye*/innervation
Eye*/pathology
Aging/*genetics
Cellular Reprogramming/*genetics
Nerve Regeneration/*genetics
Vision, Ocular/*genetics
Vision, Ocular/*physiology
Aging/physiology ; Animals ; Axons/physiology ; Cell Line, Tumor ; Cell Survival ; DNA-Binding Proteins/genetics ; Dependovirus/genetics ; Disease Models, Animal ; Female ; Genetic Vectors/genetics ; Glaucoma/genetics ; Glaucoma/pathology ; Humans ; Kruppel-Like Transcription Factors/genetics ; Mice ; Mice, Inbred C57BL ; Octamer Transcription Factor-3/genetics ; Optic Nerve Injuries/genetics ; Proto-Oncogene Proteins/genetics ; Retinal Ganglion Cells/cytology ; SOXB1 Transcription Factors/genetics ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
The Potentials and Pitfalls of a Human Cervical Organoid Model Including Langerhans Cells.
Autorzy :
Jackson R; Biotechnology Program, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.; Probe Development and Biomarker Exploration, Thunder Bay Regional Health Research Institute, Thunder Bay, ON P7B 6V4, Canada.
Lukacs JD; Department of Biology, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.
Zehbe I; Probe Development and Biomarker Exploration, Thunder Bay Regional Health Research Institute, Thunder Bay, ON P7B 6V4, Canada.; Department of Biology, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.; Northern Ontario School of Medicine, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.
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Źródło :
Viruses [Viruses] 2020 Dec 01; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Langerhans Cells*/cytology
Langerhans Cells*/metabolism
Organoids*
Cervix Uteri/*cytology
Cervix Uteri/*metabolism
Cell Culture Techniques ; Cell Differentiation ; Cell Line ; Cells, Cultured ; Cytokines/metabolism ; Female ; Humans ; Immunohistochemistry ; Models, Biological ; Tissue Culture Techniques
Czasopismo naukowe
Tytuł :
The Parabrachial Nucleus Directly Channels Spinal Nociceptive Signals to the Intralaminar Thalamic Nuclei, but Not the Amygdala.
Autorzy :
Deng J; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China. Electronic address: .
Zhou H; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China.
Lin JK; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China; University of Chinese Academy of Sciences, 19A Yu-quan Road, Beijing 100049, China.
Shen ZX; Department of Biotechnology, East China University of Science and Technology, 130 Mei-long Road, Shanghai 200237, China.
Chen WZ; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China; University of Chinese Academy of Sciences, 19A Yu-quan Road, Beijing 100049, China.
Wang LH; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China; University of Chinese Academy of Sciences, 19A Yu-quan Road, Beijing 100049, China.
Li Q; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China.
Mu D; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China.
Wei YC; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China.
Xu XH; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China.
Sun YG; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science & Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China; Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology, Shanghai 201210, China. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Sep 09; Vol. 107 (5), pp. 909-923.e6. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Afferent Pathways*/cytology
Afferent Pathways*/physiology
Intralaminar Thalamic Nuclei*/cytology
Intralaminar Thalamic Nuclei*/physiology
Parabrachial Nucleus*/cytology
Parabrachial Nucleus*/physiology
Functional Laterality/*physiology
Nociception/*physiology
Amygdala ; Animals ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Neurons/cytology ; Neurons/physiology ; Spinal Cord/cytology ; Spinal Cord/physiology
Czasopismo naukowe
Tytuł :
Long ascending propriospinal neurons provide flexible, context-specific control of interlimb coordination.
Autorzy :
Pocratsky AM; Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, United States.; Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, United States.
Shepard CT; Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, United States.; Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, United States.
Morehouse JR; Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, United States.; Department of Neurological Surgery, University of Louisville, Louisville, United States.
Burke DA; Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, United States.; Department of Neurological Surgery, University of Louisville, Louisville, United States.
Riegler AS; Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, United States.; Department of Neurological Surgery, University of Louisville, Louisville, United States.
Hardin JT; Speed School of Engineering, University of Louisville, Louisville, United States.
Beare JE; Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, United States.; Cardiovascular Innovation Institute, Department of Physiology and Biophysics, University of Louisville, Louisville, United States.
Hainline C; Speed School of Engineering, University of Louisville, Louisville, United States.
States GJ; Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, United States.; Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, United States.
Brown BL; Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, United States.
Whittemore SR; Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, United States.; Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, United States.; Department of Neurological Surgery, University of Louisville, Louisville, United States.
Magnuson DS; Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, United States.; Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, United States.; Department of Neurological Surgery, University of Louisville, Louisville, United States.; Speed School of Engineering, University of Louisville, Louisville, United States.
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Źródło :
ELife [Elife] 2020 Sep 09; Vol. 9. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Central Pattern Generators*/cytology
Central Pattern Generators*/physiology
Extremities*/innervation
Extremities*/physiology
Interneurons*/cytology
Interneurons*/physiology
Proprioception/*physiology
Animals ; Commissural Interneurons/cytology ; Commissural Interneurons/physiology ; Female ; Rats ; Rats, Sprague-Dawley ; Spinal Cord/cytology ; Spinal Cord/physiology
Czasopismo naukowe
Tytuł :
Single cell approaches to address adipose tissue stromal cell heterogeneity.
Autorzy :
Rondini EA; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, U.S.A.; Center for Integrative Metabolic and Endocrine Research, Wayne State University, Detroit, MI, U.S.A.
Granneman JG; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, U.S.A.; Center for Integrative Metabolic and Endocrine Research, Wayne State University, Detroit, MI, U.S.A.
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Źródło :
The Biochemical journal [Biochem J] 2020 Feb 14; Vol. 477 (3), pp. 583-600.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Adipose Tissue, White*/cytology
Adipose Tissue, White*/immunology
Adipose Tissue, White*/metabolism
Adipocytes/*metabolism
Macrophages/*metabolism
Stromal Cells/*cytology
Adipocytes/immunology ; Adipose Tissue/cytology ; Adipose Tissue/immunology ; Adipose Tissue/metabolism ; Animals ; Cell Communication ; Flow Cytometry ; Humans ; Macrophages/cytology ; Obesity/metabolism ; Obesity/therapy ; Sequence Analysis, RNA ; Single-Cell Analysis ; Stromal Cells/metabolism ; Stromal Cells/pathology
Czasopismo naukowe
Tytuł :
Hepatocyte Transplantation to the Liver via the Splenic Artery in a Juvenile Large Animal Model.
Autorzy :
Siefert J; Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Hillebrandt KH; Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Moosburner S; Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Podrabsky P; Radiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Geisel D; Radiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Denecke T; Radiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Unger JK; Department of Experimental Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Sawitzki B; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Gül-Klein S; Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Lippert S; Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Tang P; Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Reutzel-Selke A; Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Morgul MH; Department of General, Visceral and Transplantation Surgery, University of Münster, Münster, Germany.
Reske AW; Department of Anesthesiology and Intensive Care Medicine, University Hospital Leipzig, Leipzig, Germany.
Kafert-Kasting S; Cytonet GmbH & Co. KG, Weinheim, Germany.
Rüdinger W; Cytonet GmbH & Co. KG, Weinheim, Germany.
Oetvoes J; Department of Experimental Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Pratschke J; Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Sauer IM; Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Raschzok N; Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; BIH Charité Clinician Scientist Program, Berlin Institute of Health (BIH), Berlin, Germany.
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Źródło :
Cell transplantation [Cell Transplant] 2019 Dec; Vol. 28 (1_suppl), pp. 14S-24S. Date of Electronic Publication: 2019 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Splenic Artery*/cytology
Hepatocytes/*transplantation
Liver/*cytology
Animals ; Catheterization/methods ; Cell Transplantation/adverse effects ; Cell Transplantation/methods ; Hepatocytes/cytology ; Hepatocytes/enzymology ; Hepatocytes/immunology ; Humans ; Immunosuppression ; Liver/enzymology ; Liver/pathology ; Models, Animal ; Portal Vein/cytology ; Spleen/cytology ; Spleen/diagnostic imaging ; Spleen/pathology ; Swine ; Swine, Miniature ; Time Factors ; Tomography, X-Ray Computed ; Ultrasonography, Doppler
Czasopismo naukowe
Tytuł :
Inter- and intra-animal variation in the integrative properties of stellate cells in the medial entorhinal cortex.
Autorzy :
Pastoll H; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Garden DL; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Papastathopoulos I; The Alan Turing Institute, London, United States.; School of Mathematics, Maxwell Institute and Centre for Statistics, University of Edinburgh, Edinburgh, United Kingdom.
Sürmeli G; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Nolan MF; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
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Źródło :
ELife [Elife] 2020 Feb 13; Vol. 9. Date of Electronic Publication: 2020 Feb 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Entorhinal Cortex*/cytology
Entorhinal Cortex*/physiology
Neurons/*cytology
Action Potentials/physiology ; Animals ; Cells, Cultured ; Electrophysiology ; Female ; Grid Cells/cytology ; Male ; Mice ; Patch-Clamp Techniques ; Phenotype
Czasopismo naukowe
Tytuł :
Delayed access to feed affects broiler small intestinal morphology and goblet cell ontogeny.
Autorzy :
Liu K; Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA.
Jia M; Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA.
Wong EA; Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address: .
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Źródło :
Poultry science [Poult Sci] 2020 Nov; Vol. 99 (11), pp. 5275-5285. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Chickens*
Feeding Methods*/veterinary
Goblet Cells*/cytology
Intestine, Small*/cytology
Animal Feed ; Animals ; Intestinal Mucosa/cytology ; Random Allocation
Czasopismo naukowe
Tytuł :
Teaching Old Dogs New Tricks? The Plasticity of Lung Alveolar Macrophage Subsets.
Autorzy :
Kulikauskaite J; Immunoregulation Laboratory, Francis Crick Institute, London, UK.
Wack A; Immunoregulation Laboratory, Francis Crick Institute, London, UK. Electronic address: .
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Źródło :
Trends in immunology [Trends Immunol] 2020 Oct; Vol. 41 (10), pp. 864-877. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cell Plasticity*/immunology
Macrophages, Alveolar*/cytology
Macrophages, Alveolar*/immunology
Animals ; Humans ; Lung/cytology ; Monocytes/cytology ; Monocytes/immunology
Czasopismo naukowe
Tytuł :
Hedgehog signaling is required for endomesodermal patterning and germ cell development in the sea anemone Nematostella vectensis .
Autorzy :
Chen CY; Stowers Institute for Medical Research, Kansas City, United States.
McKinney SA; Stowers Institute for Medical Research, Kansas City, United States.
Ellington LR; Stowers Institute for Medical Research, Kansas City, United States.
Gibson MC; Stowers Institute for Medical Research, Kansas City, United States.; Department of Anatomy and Cell Biology, The University of Kansas School of Medicine, Kansas City, United States.
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Źródło :
ELife [Elife] 2020 Sep 24; Vol. 9. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Germ Layers*/cytology
Germ Layers*/growth & development
Hedgehog Proteins*/genetics
Hedgehog Proteins*/metabolism
Sea Anemones*/cytology
Sea Anemones*/genetics
Sea Anemones*/growth & development
Body Patterning/*genetics
Signal Transduction/*genetics
Animals ; Female ; Gene Knockdown Techniques ; Germ Cells/cytology ; Germ Cells/metabolism ; Life Cycle Stages/genetics ; Male
Czasopismo naukowe
Tytuł :
Osteoblast-Osteoclast Communication and Bone Homeostasis.
Autorzy :
Kim JM; Division of Rheumatology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Lin C; Division of Rheumatology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Stavre Z; Division of Rheumatology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Greenblatt MB; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
Shim JH; Division of Rheumatology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, MA 01605, USA.
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Źródło :
Cells [Cells] 2020 Sep 10; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Bone Remodeling*
Bone and Bones*/cytology
Bone and Bones*/metabolism
Osteoblasts/*cytology
Osteoclasts/*cytology
Cell Communication ; Cell Differentiation ; Homeostasis ; Humans ; Osteoclasts/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Co-culturing corncob-immobilized yeasts on orange peels for the production of pectinase.
Autorzy :
Qadir F; Department of Microbiology, University of Karachi, Karachi, Pakistan.
Ejaz U; Department of Microbiology, University of Karachi, Karachi, Pakistan.
Sohail M; Department of Microbiology, University of Karachi, Karachi, Pakistan. .
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Źródło :
Biotechnology letters [Biotechnol Lett] 2020 Sep; Vol. 42 (9), pp. 1743-1753. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Geotrichum*/cytology
Geotrichum*/enzymology
Geotrichum*/metabolism
Polygalacturonase*/analysis
Polygalacturonase*/metabolism
Saccharomyces cerevisiae*/cytology
Saccharomyces cerevisiae*/enzymology
Saccharomyces cerevisiae*/metabolism
Citrus sinensis/*chemistry
Zea mays/*chemistry
Cells, Immobilized/cytology ; Cells, Immobilized/metabolism ; Citrus sinensis/metabolism ; Coculture Techniques ; Fungal Proteins/analysis ; Fungal Proteins/metabolism ; Zea mays/metabolism
SCR Organism :
Geotrichum candidum
Czasopismo naukowe
Tytuł :
New era of trophoblast research: integrating morphological and molecular approaches.
Autorzy :
Io S; Department of Life Science Frontiers, Center for iPS Cell Research & Application, Kyoto University, Kyoto, Japan.; Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Japan Society for the Promotion of Science, Tokyo, Japan.
Kondoh E; Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Chigusa Y; Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kawasaki K; Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Mandai M; Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yamada AS; Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Congenital Anomaly Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
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Źródło :
Human reproduction update [Hum Reprod Update] 2020 Sep 01; Vol. 26 (5), pp. 611-633.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Trophoblasts*/cytology
Trophoblasts*/physiology
Biomedical Research/*trends
Molecular Biology/*trends
Animals ; Biomedical Research/methods ; Blastocyst/cytology ; Blastocyst/physiology ; Cell Differentiation/genetics ; Cell Size ; Female ; Humans ; Molecular Biology/methods ; Placenta/cytology ; Placenta/physiology ; Placentation/genetics ; Placentation/physiology ; Pregnancy ; Pregnancy Trimester, First/physiology ; Systems Integration
Czasopismo naukowe

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