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Tytuł :
Engineering brain assembloids to interrogate human neural circuits.
Autorzy :
Miura Y; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.
Li MY; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.
Revah O; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.
Yoon SJ; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.
Narazaki G; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Pașca SP; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA. .; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA. .
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Źródło :
Nature protocols [Nat Protoc] 2022 Jan; Vol. 17 (1), pp. 15-35. Date of Electronic Publication: 2022 Jan 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Nerve Net*/cytology
Nerve Net*/diagnostic imaging
Nerve Net*/physiology
Organoids*/cytology
Organoids*/diagnostic imaging
Organoids*/physiology
Brain/*cytology
Neurophysiology/*methods
Cell Culture Techniques/methods ; Cells, Cultured ; Humans ; Molecular Imaging ; Optogenetics ; Organ Culture Techniques/methods ; Pluripotent Stem Cells/cytology
Czasopismo naukowe
Tytuł :
Innervated mouse pancreas organoids as an ex vivo model to study pancreatic neuropathy in pancreatic cancer.
Autorzy :
Besikcioglu HE; Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; CRC 1321 Modelling and Targeting Pancreatic Cancer, Munich, Germany.; Department of Histology and Embryology, Institution of Health Sciences, Gazi University, Ankara, Turkey.
Yurteri Ü; Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; CRC 1321 Modelling and Targeting Pancreatic Cancer, Munich, Germany.
Munkhbaatar E; Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; CRC 1321 Modelling and Targeting Pancreatic Cancer, Munich, Germany.
Ye L; Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; CRC 1321 Modelling and Targeting Pancreatic Cancer, Munich, Germany.; Department of Histology and Embryology, Institution of Health Sciences, Gazi University, Ankara, Turkey.
Zhang F; Department of Internal Medicine I, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.
Moretti A; Department of Internal Medicine I, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.
Mota Reyes C; Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; CRC 1321 Modelling and Targeting Pancreatic Cancer, Munich, Germany.
Özoğul C; Department of Histology and Embryology, Faculty of Medicine, University of Kyrenia, Kyrenia, Cyprus.
Friess H; Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; CRC 1321 Modelling and Targeting Pancreatic Cancer, Munich, Germany.
Ceyhan GO; Department of General Surgery, HPB-Unit, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Istvanffy R; Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; CRC 1321 Modelling and Targeting Pancreatic Cancer, Munich, Germany.
Demir IE; Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; CRC 1321 Modelling and Targeting Pancreatic Cancer, Munich, Germany.; Department of General Surgery, HPB-Unit, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.; Else Kröner Clinician Scientist Professor for Translational Pancreatic Surgery.
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Źródło :
STAR protocols [STAR Protoc] 2021 Nov 17; Vol. 2 (4), pp. 100935. Date of Electronic Publication: 2021 Nov 17 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Biological*
Organoids*/cytology
Organoids*/pathology
Coculture Techniques/*methods
Pancreas/*cytology
Pancreatic Neoplasms/*pathology
Animals ; Cells, Cultured ; Mice ; Stromal Cells/cytology ; Tumor Cells, Cultured/cytology
Czasopismo naukowe
Tytuł :
A protocol for isolation of primary human immune cells from the liver and mesenteric white adipose tissue biopsies.
Autorzy :
Moreno-Fernandez ME; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45220, USA.; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Damen MSMA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45220, USA.; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Divanovic S; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45220, USA.; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; The Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
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Źródło :
STAR protocols [STAR Protoc] 2021 Nov 02; Vol. 2 (4), pp. 100937. Date of Electronic Publication: 2021 Nov 02 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Liver*/cytology
Liver*/pathology
Mesentery*/cytology
Mesentery*/pathology
Cell Separation/*methods
Immune System/*cytology
Single-Cell Analysis/*methods
Adipose Tissue, White/cytology ; Adipose Tissue, White/pathology ; Adolescent ; Biopsy ; Cells, Cultured ; Female ; Humans ; Male ; Pediatric Obesity
Czasopismo naukowe
Tytuł :
A complete temporal transcription factor series in the fly visual system.
Autorzy :
Konstantinides N; Department of Biology, New York University, New York, NY, USA. .; Université de Paris, CNRS, Institut Jacques Monod, Paris, France. .
Holguera I; Department of Biology, New York University, New York, NY, USA.
Rossi AM; Department of Biology, New York University, New York, NY, USA.; Department of Neurobiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Escobar A; Department of Biology, New York University, New York, NY, USA.
Dudragne L; Department of Biology, New York University, New York, NY, USA.
Chen YC; Department of Biology, New York University, New York, NY, USA.
Tran TN; Department of Biology, New York University, New York, NY, USA.; Center for Genomics and Systems Biology, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.
Martínez Jaimes AM; Department of Biology, New York University, New York, NY, USA.
Özel MN; Department of Biology, New York University, New York, NY, USA.
Simon F; Department of Biology, New York University, New York, NY, USA.
Shao Z; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Institute for Genomics and Multiscale Biology, New York, NY, USA.
Tsankova NM; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Fullard JF; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Institute for Genomics and Multiscale Biology, New York, NY, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Walldorf U; Developmental Biology, Saarland University, Homburg, Germany.
Roussos P; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Institute for Genomics and Multiscale Biology, New York, NY, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mental Illness Research, Education and Clinical Center (VISN 2 South), James J. Peters VA Medical Center, New York, NY, USA.
Desplan C; Department of Biology, New York University, New York, NY, USA. .; Center for Genomics and Systems Biology, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates. .
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Źródło :
Nature [Nature] 2022 Apr; Vol. 604 (7905), pp. 316-322. Date of Electronic Publication: 2022 Apr 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Drosophila Proteins*/genetics
Drosophila Proteins*/metabolism
Drosophila melanogaster*/cytology
Drosophila melanogaster*/genetics
Drosophila melanogaster*/metabolism
Gene Expression Regulation, Developmental*
Optic Lobe, Nonmammalian*/cytology
Transcription Factors*/metabolism
Vision, Ocular*
Visual Perception*
Animals ; Neural Stem Cells/cytology ; Neural Stem Cells/metabolism ; Neurons/cytology ; Neurons/metabolism ; RNA-Seq ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Conditioned medium of E17 rat brain cells induced differentiation of primary colony of mice blastocyst into neuron-like cells.
Autorzy :
Budiariati V; Department of Anatomy, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia. .
Rinendyaputri R; Center for Research and Development of Biomedical and Basic Health Technology, National Institute of Health Research and Development, Ministry of Health Republic of Indonesia, Jakarta 10560, Indonesia.
Noviantari A; Center for Research and Development of Biomedical and Basic Health Technology, National Institute of Health Research and Development, Ministry of Health Republic of Indonesia, Jakarta 10560, Indonesia.
Haq NMD; Department of Anatomy, Physiology, and Pharmacology, Faculty of Veterinary Medicine, IPB University, Bogor 16680, Indonesia.
Budiono D; Department of Anatomy, Physiology, and Pharmacology, Faculty of Veterinary Medicine, IPB University, Bogor 16680, Indonesia.
Pristihadi DN; Department of Anatomy, Physiology, and Pharmacology, Faculty of Veterinary Medicine, IPB University, Bogor 16680, Indonesia.
Juliandi B; Department of Biology, Faculty of Mathematics and Natural Sciences, IPB University, Bogor 16680, Indonesia.
Fahrudin M; Department of Anatomy, Physiology, and Pharmacology, Faculty of Veterinary Medicine, IPB University, Bogor 16680, Indonesia.
Boediono A; Department of Anatomy, Physiology, and Pharmacology, Faculty of Veterinary Medicine, IPB University, Bogor 16680, Indonesia.
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Źródło :
Journal of veterinary science [J Vet Sci] 2021 Nov; Vol. 22 (6), pp. e86.
Typ publikacji :
Journal Article
MeSH Terms :
Culture Media, Conditioned*
Neurons*/cytology
Secretome*
Blastocyst/*cytology
Animals ; Brain/cytology ; Cell Differentiation ; Mice ; Rats
Czasopismo naukowe
Tytuł :
The effect of erythrocyte lysing reagents on enumeration of leukocyte subpopulations compared with a no-lyse-no-wash protocol.
Autorzy :
Plank K; Universität Erlangen-Nürnberg, Erlangen, Germany.
Dorn C; Medizinische Klinik 5, Universitätsklinikum Erlangen, Erlangen, Germany.
Krause SW; Medizinische Klinik 5, Universitätsklinikum Erlangen, Erlangen, Germany.
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Źródło :
International journal of laboratory hematology [Int J Lab Hematol] 2021 Oct; Vol. 43 (5), pp. 939-947. Date of Electronic Publication: 2021 Feb 13.
Typ publikacji :
Journal Article
MeSH Terms :
Erythrocytes*/cytology
Erythrocytes*/drug effects
Antigens, CD/*analysis
Flow Cytometry/*methods
Leukocyte Count/*methods
Lymphocyte Subsets/*cytology
Hemolysis/drug effects ; Humans ; Indicators and Reagents ; Leukocytes/cytology
Czasopismo naukowe
Tytuł :
Regulation of gingival fibroblast phenotype by periodontal ligament cells in vitro.
Autorzy :
Garna DF; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.; Department of Periodontology, Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia.
Hughes FJ; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.
Ghuman MS; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.
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Źródło :
Journal of periodontal research [J Periodontal Res] 2022 Apr; Vol. 57 (2), pp. 402-411. Date of Electronic Publication: 2022 Jan 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gingiva*/cytology
Periodontal Ligament*/cytology
Fibroblasts/*cytology
Alkaline Phosphatase/metabolism ; Cell Differentiation ; Cells, Cultured ; Humans ; Phenotype
Czasopismo naukowe
Tytuł :
Aged mice ovaries harbor stem cells and germ cell nests but fail to form follicles.
Autorzy :
Sharma D; Stem Cell Biology Department, ICMR- National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Mumbai, 400, 012, India.
Bhartiya D; Stem Cell Biology Department, ICMR- National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Mumbai, 400, 012, India. .
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Źródło :
Journal of ovarian research [J Ovarian Res] 2022 Mar 23; Vol. 15 (1), pp. 37. Date of Electronic Publication: 2022 Mar 23.
Typ publikacji :
Journal Article
MeSH Terms :
Germ Cells*/cytology
Germ Cells*/physiology
Ovarian Follicle*/growth & development
Ovary*/cytology
Ovary*/physiology
Animals ; Cellular Senescence ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/physiology ; Female ; Humans ; Mice ; Oocytes ; Transcription Factors
Czasopismo naukowe
Tytuł :
Developmental and evolutionary constraints on olfactory circuit selection.
Autorzy :
Hiratani N; Gatsby Computational Neuroscience Unit, University College London, London W1T 4JG, United Kingdom.
Latham PE; Gatsby Computational Neuroscience Unit, University College London, London W1T 4JG, United Kingdom.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Mar 15; Vol. 119 (11), pp. e2100600119. Date of Electronic Publication: 2022 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Insecta*
Learning*/physiology
Mammals*
Models, Neurological*
Olfactory Pathways*/cytology
Olfactory Pathways*/growth & development
Animals ; Biological Evolution ; Cell Count ; Mushroom Bodies/cytology ; Neural Networks, Computer ; Neurons/cytology ; Piriform Cortex/cytology
Czasopismo naukowe
Tytuł :
Human 8-cell-like cells discovered.
Autorzy :
Balaton BP; KU Leuven-University of Leuven, Department of Development and Regeneration, Leuven Institute for Single-Cell Omics (LISCO), Leuven Stem Cell Institute, Leuven, Belgium. Electronic address: .
Pasque V; KU Leuven-University of Leuven, Department of Development and Regeneration, Leuven Institute for Single-Cell Omics (LISCO), Leuven Stem Cell Institute, Leuven, Belgium. Electronic address: .
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Źródło :
Cell stem cell [Cell Stem Cell] 2022 Mar 03; Vol. 29 (3), pp. 347-348.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Germ Layers*/cytology
Pluripotent Stem Cells*/cytology
Embryo, Mammalian/cytology ; Humans
Czasopismo naukowe
Tytuł :
Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling.
Autorzy :
Yan Q; Department of Biochemistry, School of Medicine, Southern University of Science and Technology, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Shenzhen, China.
Gao H; Department of Biochemistry, School of Medicine, Southern University of Science and Technology, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Shenzhen, China.
Yao Q; Department of Biochemistry, School of Medicine, Southern University of Science and Technology, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Shenzhen, China.
Ling K; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.
Xiao G; Department of Biochemistry, School of Medicine, Southern University of Science and Technology, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Shenzhen, China. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2022 Mar; Vol. 298 (3), pp. 101639. Date of Electronic Publication: 2022 Jan 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Diseases, Metabolic*/genetics
Bone Diseases, Metabolic*/metabolism
Bone Resorption*/enzymology
Bone Resorption*/metabolism
Mesenchymal Stem Cells*/cytology
Mesenchymal Stem Cells*/enzymology
Mesenchymal Stem Cells*/metabolism
Phosphotransferases (Alcohol Group Acceptor)*/deficiency
Phosphotransferases (Alcohol Group Acceptor)*/metabolism
Animals ; Bone Remodeling/physiology ; Calcium/metabolism ; Cell Differentiation/physiology ; Mice ; Osteoblasts/cytology ; Osteoblasts/enzymology ; Osteoblasts/metabolism ; Osteoclasts/cytology ; Osteoclasts/enzymology ; Osteoclasts/metabolism ; Osteogenesis ; RANK Ligand/metabolism
Czasopismo naukowe
Tytuł :
Protocol for targeting the magnocellular neuroendocrine cell ensemble via retrograde tracing from the posterior pituitary.
Autorzy :
Zhang B; Department of Neurobiology and Department of Neurology of Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, China.; The MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Brain Science and Brain Medicine, Hangzhou 310058, China.
Qiu L; Department of Neurobiology and Department of Neurology of Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, China.; The MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Brain Science and Brain Medicine, Hangzhou 310058, China.
Long C; Department of Neurobiology and Department of Neurology of Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, China.; The MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Brain Science and Brain Medicine, Hangzhou 310058, China.
Gao Z; Department of Neurobiology and Department of Neurology of Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, China.; The MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Brain Science and Brain Medicine, Hangzhou 310058, China.
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Źródło :
STAR protocols [STAR Protoc] 2021 Aug 27; Vol. 2 (3), pp. 100787. Date of Electronic Publication: 2021 Aug 27 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuroendocrine Cells*/cytology
Neuroendocrine Cells*/physiology
Hypothalamus/*cytology
Optogenetics/*methods
Pituitary Gland, Posterior/*cytology
Animals ; Animals, Genetically Modified ; Male ; Median Eminence/cytology ; Nerve Net/cytology ; Nerve Net/physiology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Microglia replacement by bone marrow transplantation (Mr BMT) in the central nervous system of adult mice.
Autorzy :
Xu Z; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Zhou X; Department of Neurosurgery, Huashan Hospital, Institute for Translational Brain Research, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200032, China.
Peng B; Department of Neurosurgery, Huashan Hospital, Institute for Translational Brain Research, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200032, China.
Rao Y; Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 201108, China.
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Źródło :
STAR protocols [STAR Protoc] 2021 Jul 07; Vol. 2 (3), pp. 100666. Date of Electronic Publication: 2021 Jul 07 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Central Nervous System*/cytology
Central Nervous System*/surgery
Microglia*/cytology
Microglia*/physiology
Bone Marrow Cells/*cytology
Bone Marrow Transplantation/*methods
Animals ; Brain/cytology ; Female ; Male ; Mice ; Spinal Cord/cytology ; Transplantation, Homologous
Czasopismo naukowe
Tytuł :
Epithelial monitoring through ligand-receptor segregation ensures malignant cell elimination.
Autorzy :
de Vreede G; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Gerlach SU; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Bilder D; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2022 Apr 15; Vol. 376 (6590), pp. 297-301. Date of Electronic Publication: 2022 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Cell Polarity*/physiology
Cell Transformation, Neoplastic*/pathology
Drosophila Proteins*/genetics
Drosophila Proteins*/metabolism
Drosophila melanogaster*/cytology
Drosophila melanogaster*/physiology
Epithelial Cells*/physiology
Animals ; Imaginal Discs/cytology ; Ligands ; Signal Transduction
Czasopismo naukowe
Tytuł :
Receptor activity-modifying protein 1 regulates mouse skin fibroblast proliferation via the Gαi3-PKA-CREB-YAP axis.
Autorzy :
Yin S; Department of Plastic Surgery, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.; Department of Plastic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Song R; Department of Plastic Surgery, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Ma J; Department of Plastic Surgery, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Liu C; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.; Department of Plastic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Wu Z; Department of Plastic Surgery, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Cao G; Department of Plastic Surgery, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Liu J; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.; Department of Plastic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Zhang G; Department of Plastic Surgery, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Zhang H; Department of Plastic Surgery, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Sun R; Department of Plastic Surgery, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Chen A; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.; Department of Plastic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China.
Wang Y; Department of Plastic Surgery, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China. .; Jinan Clinical Research Center for Tissue Engineering Skin Regeneration and Wound Repair, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China. .; Department of Plastic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, People's Republic of China. .
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Źródło :
Cell communication and signaling : CCS [Cell Commun Signal] 2022 Apr 12; Vol. 20 (1), pp. 52. Date of Electronic Publication: 2022 Apr 12.
Typ publikacji :
Journal Article; Video-Audio Media
MeSH Terms :
Cyclic AMP-Dependent Protein Kinases*/metabolism
GTP-Binding Protein alpha Subunits, Gi-Go*/metabolism
Receptor Activity-Modifying Protein 1*/genetics
Receptor Activity-Modifying Protein 1*/metabolism
Signal Transduction*
Skin*/cytology
Skin*/metabolism
YAP-Signaling Proteins*/metabolism
Animals ; Cell Proliferation ; Cyclic AMP Response Element-Binding Protein/metabolism ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Mice
Czasopismo naukowe
Tytuł :
[Expression Level of SOCS3 in Acute Lymphoblastic Leukemia Cells Affects the Cytotoxicity of NK Cells].
Autorzy :
Tang B; Clinical Department of Nanyang Medical College,Nanyang 473061, Henan Province, China.
Li YG; Clinical Department of Nanyang Medical College,Nanyang 473061, Henan Province, China.
Cheng L; Clinical Department of Nanyang Medical College,Nanyang 473061, Henan Province, China.
Dang HB; Department of Hematology, The First Affiliated Hospital of Nanyang Medical College, Nanyang 73000, Henan Province, China,E-mail: .
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Źródło :
Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2022 Apr; Vol. 30 (2), pp. 400-406.
Typ publikacji :
Journal Article
MeSH Terms :
Killer Cells, Natural*/cytology
NK Cell Lectin-Like Receptor Subfamily K*/metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics
Suppressor of Cytokine Signaling 3 Protein*/metabolism
Child ; Histocompatibility Antigens Class I/genetics ; Histocompatibility Antigens Class I/metabolism ; Humans ; Leukocytes, Mononuclear/cytology ; Ligands ; RNA, Messenger/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Spatial and temporal immunoreaction of nestin, CD44, collagen IX and GFAP in human retinal Müller cells in the developing fetal eye.
Autorzy :
Bulirsch LM; Department of Ophthalmology, University Hospital Bonn, Germany; Division of Ophthalmic Pathology, Department of Ophthalmology, University Hospital Bonn, Germany. Electronic address: .
Loeffler KU; Department of Ophthalmology, University Hospital Bonn, Germany; Division of Ophthalmic Pathology, Department of Ophthalmology, University Hospital Bonn, Germany.
Holz FG; Department of Ophthalmology, University Hospital Bonn, Germany.
Koinzer S; Augenarzt am Dreiecksplatz and Department of Ophthalmology, University Hospital of Schleswig-Holstein, Campus Kiel, Germany.
Nadal J; Department of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Germany.
Müller AM; Center of Pediatric Pathology and Pathology, University Hospital Cologne, Germany.
Herwig-Carl MC; Department of Ophthalmology, University Hospital Bonn, Germany; Division of Ophthalmic Pathology, Department of Ophthalmology, University Hospital Bonn, Germany.
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Źródło :
Experimental eye research [Exp Eye Res] 2022 Apr; Vol. 217, pp. 108958. Date of Electronic Publication: 2022 Jan 24.
Typ publikacji :
Journal Article
MeSH Terms :
Collagen Type IX*/metabolism
Ependymoglial Cells*/cytology
Ependymoglial Cells*/metabolism
Glial Fibrillary Acidic Protein*/metabolism
Hyaluronan Receptors*/metabolism
Nestin*/metabolism
Retina*/embryology
Retina*/metabolism
Fetus ; Humans ; Infant ; Neuroglia/cytology ; Neuroglia/metabolism
Czasopismo naukowe
Tytuł :
Mechanism of CircANKRD36 regulating cell heterogeneity and endothelial mesenchymal transition in aortic valve stromal cells by regulating miR-599 and TGF-β signaling pathway.
Autorzy :
Zhang C; Cardiac laboratory, Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Liu M; Cardiac laboratory, Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wang X; Cardiac laboratory, Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Chen S; Cardiac laboratory, Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Fu X; Cardiac laboratory, Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Li G; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Dong N; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Shang X; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address: .
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Źródło :
International journal of cardiology [Int J Cardiol] 2022 Apr 01; Vol. 352, pp. 104-114. Date of Electronic Publication: 2022 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
MicroRNAs*
Nuclear Proteins*/genetics
Osteogenesis*/genetics
Stromal Cells*/cytology
Stromal Cells*/metabolism
Aortic Diseases ; Aortic Valve/cytology ; Aortic Valve/metabolism ; Calcinosis ; Cell Differentiation ; Cells, Cultured ; Humans ; RNA, Circular ; Signal Transduction/genetics ; Transforming Growth Factor beta/genetics ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
General Control Nonrepressed Protein 5 Modulates Odontogenic Differentiation Through NF-κB Pathway in Tumor Necrosis Factor-α-Mediated Impaired Human Dental Pulp Stem Cells.
Autorzy :
Xiao J; Department of Stomatology, Haimen District People's Hospital, Nantong, China.
Zheng Y; Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
Zhang W; Department of Stomatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, China.
Zhang Y; Jiangsu Vocational College of Medicine, Yancheng, China.
Cao P; Nantong Boyue Dentistry Out-patient Department, Nantong, China.
Liang Y; Department of Stomatology, Shanghai East Hospital Affiliated with Tongji University, Shanghai, China.
Bao L; Department of Stomatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, China.
Shi S; Department of Stomatology, Haimen District People's Hospital, Nantong, China.
Feng X; Department of Stomatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, China.
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Źródło :
Cellular reprogramming [Cell Reprogram] 2022 Apr; Vol. 24 (2), pp. 95-104. Date of Electronic Publication: 2022 Feb 16.
Typ publikacji :
Journal Article
MeSH Terms :
Histone Acetyltransferases*/genetics
NF-kappa B*/metabolism
Osteogenesis*/physiology
Stem Cells*/cytology
Tumor Necrosis Factor-alpha*/pharmacology
Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; Dental Pulp/cytology ; Humans
Czasopismo naukowe
Tytuł :
Inhibition of RIP3 increased ADSC viability under OGD and modified the competency of adipogenesis, angiogenesis, and inflammation regulation.
Autorzy :
Yang Z; Chinese Academy of Medical Sciences and Peking Union Medical College Plastic Surgery Hospital and Institute, Beijing, China.
Qi Z; Chinese Academy of Medical Sciences and Peking Union Medical College Plastic Surgery Hospital and Institute, Beijing, China.
Yang X; Chinese Academy of Medical Sciences and Peking Union Medical College Plastic Surgery Hospital and Institute, Beijing, China.
Gao Q; Chinese Academy of Medical Sciences and Peking Union Medical College Plastic Surgery Hospital and Institute, Beijing, China.
Hu Y; Chinese Academy of Medical Sciences and Peking Union Medical College Plastic Surgery Hospital and Institute, Beijing, China.
Yuan X; Chinese Academy of Medical Sciences and Peking Union Medical College Plastic Surgery Hospital and Institute, Beijing, China.
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Źródło :
Bioscience reports [Biosci Rep] 2022 Mar 31; Vol. 42 (3).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucose*/pharmacology
Stem Cells*/cytology
Vascular Endothelial Growth Factor A*
Adipogenesis ; Adipose Tissue/cytology ; Apoptosis ; Fibroblast Growth Factor 2 ; Human Umbilical Vein Endothelial Cells ; Humans ; Inflammation ; Oxygen/pharmacology ; Receptor-Interacting Protein Serine-Threonine Kinases/antagonists & inhibitors
Czasopismo naukowe

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