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Wyszukujesz frazę ""Cytostatic Agents"" wg kryterium: Temat


Tytuł :
New insights into transformation pathways of a mixture of cytostatic drugs using Polyester-TiO 2 films: Identification of intermediates and toxicity assessment.
Autorzy :
Evgenidou E; Laboratory of Environmental Pollution Control, Department of Chemistry, Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece; Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, Thessaloniki GR-57001, Greece.
Ofrydopoulou A; Laboratory of Environmental Pollution Control, Department of Chemistry, Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece; Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, Thessaloniki GR-57001, Greece.
Malesic-Eleftheriadou N; Laboratory of Environmental Pollution Control, Department of Chemistry, Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece; Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, Thessaloniki GR-57001, Greece.
Nannou C; Laboratory of Environmental Pollution Control, Department of Chemistry, Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece; Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, Thessaloniki GR-57001, Greece.
Ainali NM; Laboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece.
Christodoulou E; Laboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece.
Bikiaris DN; Laboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece.
Kyzas GZ; Department of Chemistry, International Hellenic University, GR-654 04 Kavala, Greece.
Lambropoulou DA; Laboratory of Environmental Pollution Control, Department of Chemistry, Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece; Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, Thessaloniki GR-57001, Greece. Electronic address: .
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Źródło :
The Science of the total environment [Sci Total Environ] 2020 Nov 01; Vol. 741, pp. 140394. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Cytostatic Agents*
Water Pollutants, Chemical/*analysis
Animals ; Catalysis ; Cyclophosphamide ; Photolysis ; Titanium
Czasopismo naukowe
Tytuł :
New insights on cytostatic drug risk assessment in aquatic environments based on measured concentrations in surface waters.
Autorzy :
Gouveia TIA; LEPABE - Laboratory for Process, Environmental, Biotechnology and Energy Engineering, Faculty of Engineering, University of Porto, R. Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal.
Alves A; LEPABE - Laboratory for Process, Environmental, Biotechnology and Energy Engineering, Faculty of Engineering, University of Porto, R. Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal.
Santos MSF; LEPABE - Laboratory for Process, Environmental, Biotechnology and Energy Engineering, Faculty of Engineering, University of Porto, R. Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal. Electronic address: .
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Źródło :
Environment international [Environ Int] 2019 Dec; Vol. 133 (Pt B), pp. 105236. Date of Electronic Publication: 2019 Oct 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytostatic Agents*/analysis
Cytostatic Agents*/toxicity
Water Pollutants, Chemical*/analysis
Water Pollutants, Chemical*/toxicity
Fresh Water/*chemistry
Risk Assessment/*methods
Aquatic Organisms/drug effects ; Environmental Monitoring/methods ; Waste Water/chemistry
Czasopismo naukowe
Tytuł :
Added value recyclability of glass fiber waste as photo-oxidation catalyst for toxic cytostatic micropollutants.
Autorzy :
Nechifor G; Faculty of Applied Chemistry and Material Science, Polytechnic University of Bucharest, 060042, Bucharest, Romania.
Totu EE; Faculty of Applied Chemistry and Material Science, Polytechnic University of Bucharest, 060042, Bucharest, Romania. .
Nechifor AC; Faculty of Applied Chemistry and Material Science, Polytechnic University of Bucharest, 060042, Bucharest, Romania.
Constantin L; National Research and Development Institute for Industrial Ecology - ECOIND Bucharest, 71-73 Drumul Podul Dambovitei Str., 060652, Bucharest, Romania.
Constantin AM; National Research and Development Institute for Industrial Ecology - ECOIND Bucharest, 71-73 Drumul Podul Dambovitei Str., 060652, Bucharest, Romania.
Cărăuşu ME; Department of Public Health and Management, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115, Iasi, Romania.
Isildak I; Department of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, 34210, Esenler-Istanbul, Turkey.
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Źródło :
Scientific reports [Sci Rep] 2020 Jan 10; Vol. 10 (1), pp. 136. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Photochemical Processes*
Waste Products*
Cytostatic Agents/*chemistry
Environmental Pollutants/*chemistry
Glass/*chemistry
Recycling/*methods
Silicon Dioxide/*chemistry
Catalysis ; Cytostatic Agents/toxicity ; Environmental Pollutants/toxicity ; Microspheres ; Oxidation-Reduction ; Surface Properties ; Titanium/chemistry
Czasopismo naukowe
Tytuł :
Cytostatic pharmaceuticals as water contaminants.
Autorzy :
Jureczko M; Environmental Biotechnology Department, Faculty of Energy and Environmental Engineering, The Silesian University of Technology, Akademicka 2 Str., 44-100, Gliwice, Poland; The Biotechnology Centre, The Silesian University of Technology, Krzywoustego 8 Str., 44-100, Gliwice, Poland. Electronic address: .
Kalka J; Environmental Biotechnology Department, Faculty of Energy and Environmental Engineering, The Silesian University of Technology, Akademicka 2 Str., 44-100, Gliwice, Poland.
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2020 Jan 05; Vol. 866, pp. 172816. Date of Electronic Publication: 2019 Nov 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cytostatic Agents/*analysis
Water/*chemistry
Water Pollutants, Chemical/*analysis
Animals ; Antineoplastic Agents/analysis ; Antineoplastic Agents/toxicity ; Cytostatic Agents/toxicity ; Environment ; Humans ; Risk Assessment ; Water Pollutants, Chemical/toxicity
Czasopismo naukowe
Tytuł :
Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin.
Autorzy :
Sivalingam VN; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.; Department of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Latif A; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Kitson S; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.; Department of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
McVey R; Department of Histopathology, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Finegan KG; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Marshall K; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Lisanti MP; School of Environmental & Life Sciences, University of Salford, Salford, UK.
Sotgia F; School of Environmental & Life Sciences, University of Salford, Salford, UK.
Stratford IJ; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Crosbie EJ; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK. .; Department of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. .
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Źródło :
British journal of cancer [Br J Cancer] 2020 Jan; Vol. 122 (1), pp. 62-71. Date of Electronic Publication: 2019 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia/*drug effects
Cytostatic Agents/*therapeutic use
Endometrial Neoplasms/*drug therapy
Endometrial Neoplasms/*metabolism
Hyperglycemia/*metabolism
Hypoglycemic Agents/*therapeutic use
Metformin/*therapeutic use
Antigens, Neoplasm/genetics ; Antigens, Neoplasm/metabolism ; Carbonic Anhydrase IX/genetics ; Carbonic Anhydrase IX/metabolism ; Cell Hypoxia/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cytostatic Agents/administration & dosage ; Endometrial Neoplasms/pathology ; Female ; Gene Expression Regulation, Neoplastic ; Glucose/metabolism ; Humans ; Hypoglycemic Agents/administration & dosage ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Ki-67 Antigen/metabolism ; Metformin/administration & dosage ; Metformin/adverse effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; Preoperative Care/methods ; Signal Transduction/drug effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
The synthesis of a novel Crizotinib heptamethine cyanine dye conjugate that potentiates the cytostatic and cytotoxic effects of Crizotinib in patient-derived glioblastoma cell lines.
Autorzy :
Choi PJ; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Cooper E; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Department of Pharmacology & The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Neurosurgical Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Schweder P; Neurosurgical Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Department of Neurosurgery, Auckland City Hospital, Private Bag 92024, Auckland 1142, New Zealand.
Mee E; Neurosurgical Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Department of Neurosurgery, Auckland City Hospital, Private Bag 92024, Auckland 1142, New Zealand.
Faull R; Neurosurgical Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Denny WA; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Dragunow M; Department of Pharmacology & The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Neurosurgical Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Park TI; Department of Pharmacology & The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Neurosurgical Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Jose J; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Sep 15; Vol. 29 (18), pp. 2617-2621. Date of Electronic Publication: 2019 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Brain Neoplasms/*drug therapy
Carbocyanines/*pharmacology
Crizotinib/*pharmacology
Cytostatic Agents/*pharmacology
Fluorescent Dyes/*pharmacology
Glioblastoma/*drug therapy
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/metabolism ; Carbocyanines/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Crizotinib/chemistry ; Cytostatic Agents/chemical synthesis ; Cytostatic Agents/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Fluorescent Dyes/chemical synthesis ; Fluorescent Dyes/chemistry ; Glioblastoma/diagnostic imaging ; Glioblastoma/metabolism ; Humans ; Molecular Structure ; Optical Imaging ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Liquid-liquid extraction as a simple tool to quickly quantify fourteen cytostatics in urban wastewaters and access their impact in aquatic biota.
Autorzy :
Gouveia TIA; LEPABE - Laboratory for Process, Environmental, Biotechnology and Energy Engineering, Faculty of Engineering, University of Porto, R. Dr. Roberto Frias, 4200-465 Porto, Portugal.
Silva AMT; Laboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials (LSRE-LCM), Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.
Ribeiro AR; Laboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials (LSRE-LCM), Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.
Alves A; LEPABE - Laboratory for Process, Environmental, Biotechnology and Energy Engineering, Faculty of Engineering, University of Porto, R. Dr. Roberto Frias, 4200-465 Porto, Portugal.
Santos MSF; LEPABE - Laboratory for Process, Environmental, Biotechnology and Energy Engineering, Faculty of Engineering, University of Porto, R. Dr. Roberto Frias, 4200-465 Porto, Portugal. Electronic address: .
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Źródło :
The Science of the total environment [Sci Total Environ] 2020 Oct 20; Vol. 740, pp. 139995. Date of Electronic Publication: 2020 Jun 05.
Typ publikacji :
Journal Article
MeSH Terms :
Cytostatic Agents/*analysis
Water Pollutants, Chemical/*analysis
Biota ; Environmental Monitoring ; Humans ; Liquid-Liquid Extraction ; Waste Water/analysis
Czasopismo naukowe
Tytuł :
Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer.
Autorzy :
Yuan SJ; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China.; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 43007, China.
Xu YH; Department of Ophthalmology, Institute of Ophthalmological Research, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Wang C; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China.; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 43007, China.
An HC; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China.; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 43007, China.
Xu HZ; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China.; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 43007, China.
Li K; Center for Lab Teaching, School of Basic Medicine, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China.
Komatsu N; Graduate School of Human and Environmental Studies, Kyoto University, Sakyo-ku, Kyoto, 606-8501, Japan.
Zhao L; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection & School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, Jiangsu, China. .
Chen X; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China. .; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 43007, China. .
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Źródło :
Journal of nanobiotechnology [J Nanobiotechnology] 2019 Oct 17; Vol. 17 (1), pp. 110. Date of Electronic Publication: 2019 Oct 17.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Cytostatic Agents/*administration & dosage
Doxorubicin/*administration & dosage
Glycerol/*chemistry
Nanoconjugates/*chemistry
Polymers/*chemistry
Triple Negative Breast Neoplasms/*drug therapy
Animals ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Cytostatic Agents/therapeutic use ; Doxorubicin/therapeutic use ; Drug Resistance, Neoplasm/drug effects ; Female ; Humans ; Immune Tolerance/drug effects ; Mice, Inbred BALB C ; Nanodiamonds/chemistry ; Triple Negative Breast Neoplasms/immunology ; Tumor Microenvironment/drug effects
Czasopismo naukowe
Tytuł :
Removal of anthracycline cytostatics from aquatic environment: Comparison of nanocrystalline titanium dioxide and decontamination agents.
Autorzy :
Šťastný M; Institute of Inorganic Chemistry of the Czech Academy of Sciences, Řež, Czech Republic.
Štengl V; Institute of Inorganic Chemistry of the Czech Academy of Sciences, Řež, Czech Republic.
Štenglová-Netíková I; 1st Faculty of Medicine, Charles University in Prague, Ovocný trh, Czech Republic.
Šrámová-Slušná M; Institute of Inorganic Chemistry of the Czech Academy of Sciences, Řež, Czech Republic.
Janoš P; Faculty of the Environment, J.E.Purkyně University in Ústí nad Labem, Ústí nad Labem, Czech Republic.
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Źródło :
PloS one [PLoS One] 2019 Oct 11; Vol. 14 (10), pp. e0223117. Date of Electronic Publication: 2019 Oct 11 (Print Publication: 2019).
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Cytostatic Agents/*chemistry
Doxorubicin/*analogs & derivatives
Nanostructures/*chemistry
Titanium/*chemistry
Water Pollutants, Chemical/*chemistry
Adsorption ; Crystallization ; Cytostatic Agents/isolation & purification ; Decontamination/methods ; Doxorubicin/chemistry ; Doxorubicin/isolation & purification ; Hydrolysis ; Particle Size ; Sodium Hydroxide/chemistry ; Sodium Hypochlorite/chemistry ; Surface Properties ; Water Pollutants, Chemical/isolation & purification
Czasopismo naukowe
Tytuł :
Biochemical profile and in vitro biological activities of extracts from seven folk medicinal plants growing wild in southern Tunisia.
Autorzy :
Tlili H; Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms, Institute of Arid Regions (IRA), Medenine, Tunisia.
Hanen N; Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms, Institute of Arid Regions (IRA), Medenine, Tunisia.
Ben Arfa A; Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms, Institute of Arid Regions (IRA), Medenine, Tunisia.
Neffati M; Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms, Institute of Arid Regions (IRA), Medenine, Tunisia.
Boubakri A; Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms, Institute of Arid Regions (IRA), Medenine, Tunisia.
Buonocore D; Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Dossena M; Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Verri M; Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Doria E; Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.
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Źródło :
PloS one [PLoS One] 2019 Sep 17; Vol. 14 (9), pp. e0213049. Date of Electronic Publication: 2019 Sep 17 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*chemistry
Cytostatic Agents/*chemistry
Magnoliopsida/*chemistry
Plant Extracts/*chemistry
Anti-Inflammatory Agents/pharmacology ; Caco-2 Cells ; Cell Proliferation/drug effects ; Cytostatic Agents/pharmacology ; Humans ; Plant Extracts/pharmacology ; Plants, Medicinal/chemistry ; Tunisia
Czasopismo naukowe
Tytuł :
Cytostatic cancer therapy modulates monocyte-macrophage cell functions: how it impacts on treatment outcomes.
Autorzy :
Patysheva M; Tomsk State University, Tomsk 634050, Russia.
Stakheyeva M; Tomsk State University, Tomsk 634050, Russia.
Larionova I; Tomsk State University, Tomsk 634050, Russia.
Fedorov A; Cancer Research Institute, Tomsk National Research Medical Center of Russian Academy of Sciences, Tomsk 634009, Russia.
Kzhyshkowska J; Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer, 1-3, Mannheim 68167, Germany.
Cherdyntseva N; Cancer Research Institute, Tomsk National Research Medical Center of Russian Academy of Sciences, Tomsk 634009, Russia.
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Źródło :
Experimental oncology [Exp Oncol] 2019 Sep; Vol. 41 (3), pp. 248-253.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents/*pharmacology
Cytostatic Agents/*pharmacology
Macrophages/*drug effects
Monocytes/*drug effects
Animals ; Antineoplastic Agents/therapeutic use ; Cytostatic Agents/therapeutic use ; Humans ; Macrophage Activation/drug effects ; Macrophage Activation/immunology ; Macrophages/immunology ; Macrophages/metabolism ; Monocytes/immunology ; Monocytes/metabolism ; Neoplasms/drug therapy ; Neoplasms/etiology ; Neoplasms/metabolism ; Neoplasms/pathology ; Tumor Microenvironment/drug effects ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
Organoseleno cytostatic derivatives: Autophagic cell death with AMPK and JNK activation.
Autorzy :
Garnica P; Universidad de Navarra, Facultad de Farmacia y Nutrición, Departamento de Tecnología y Química Farmacéuticas, Campus Universitario, 31080, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Irunlarrea 3, E-31008, Pamplona, Spain.
Encío I; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Irunlarrea 3, E-31008, Pamplona, Spain; Department of Health Sciences, Public University of Navarra, Avda. Barañain s/n, E-31008, Pamplona, Spain.
Plano D; Universidad de Navarra, Facultad de Farmacia y Nutrición, Departamento de Tecnología y Química Farmacéuticas, Campus Universitario, 31080, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Irunlarrea 3, E-31008, Pamplona, Spain.
Palop JA; Universidad de Navarra, Facultad de Farmacia y Nutrición, Departamento de Tecnología y Química Farmacéuticas, Campus Universitario, 31080, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Irunlarrea 3, E-31008, Pamplona, Spain.
Sanmartín C; Universidad de Navarra, Facultad de Farmacia y Nutrición, Departamento de Tecnología y Química Farmacéuticas, Campus Universitario, 31080, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Irunlarrea 3, E-31008, Pamplona, Spain. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2019 Aug 01; Vol. 175, pp. 234-246. Date of Electronic Publication: 2019 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Adenylate Kinase/*metabolism
Autophagy/*drug effects
Cell Death/*drug effects
Cytostatic Agents/*pharmacology
MAP Kinase Kinase 4/*metabolism
Organoselenium Compounds/*pharmacology
Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cytostatic Agents/administration & dosage ; Cytostatic Agents/chemistry ; Dose-Response Relationship, Drug ; Enzyme Activation ; Humans ; Organoselenium Compounds/administration & dosage ; Organoselenium Compounds/chemistry ; S Phase/drug effects
Czasopismo naukowe
Tytuł :
[Cytostatic and cytotoxic waste - rules of conduct in Poland].
Autorzy :
Furtak-Niczyporuk M; Uniwersytet Medyczny w Lublinie / Medical University of Lublin, Lublin, Poland (Katedra i Zakład Zdrowia Publicznego / Department of Public Health). .
Jaroszyński J; Uniwersytet Marii Curie-Skłodowskiej w Lublinie / Maria Curie-Sklodowska University of Lublin, Lublin, Poland (Wydział Prawa i Administracji, Katedra Postępowania Administracyjnego / Faculty of Law and Administration, Department of Administrative Procedure). .
Mela A; Warszawski Uniwersytet Medyczny / Medical University of Warsaw, Warsaw, Poland (Katedra i Zakład Farmakologii Doświadczalnej i Klinicznej / Department of Experimental and Clinical Pharmacology). .
Staniszewska A; Warszawski Uniwersytet Medyczny / Medical University of Warsaw, Warsaw, Poland (Katedra i Zakład Farmakologii Doświadczalnej i Klinicznej / Department of Experimental and Clinical Pharmacology). .
Piotrowska J; Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi / Copernicus Provincial Multidisciplinary Centre of Oncology and Traumatology in Lodz, Łódź, Poland. .
Zimmermann A; Uniwersytet Medyczny w Gdańsku / Medical University of Gdansk, Gdańsk, Poland (Zakład Prawa Medycznego i Farmaceutycznego / Department of Medical and Pharmacy Law). .
Czajka-Bełz A; Centralny Szpital Kliniczny Ministerstwa Spraw Wewnętrznych i Administracji w Warszawie / Central Clinical Hospital of Ministry of the Interior and Administration in Warsaw, Warsaw, Poland (Klinika Neurologii / Clinical Department of Neurology). .
Dreher P; Uniwersytet Medyczny w Lublinie / Medical University of Lublin, Lublin, Poland (Katedra i Zakład Zdrowia Publicznego / Department of Public Health). .
Dąbrowski J; Instytut Medycyny Doświadczalnej i Klinicznej. im. M. Mossakowskiego Polskiej Akademii Nauk / Mossakowski Medical Research Centre Polish Academy of Sciences, Warsaw, Poland (Zakład Fizjologii Stosowanej / Department of Applied Physiology). .
Kapka-Skrzypczak L; Instytut Medycyny Wsi im. Witolda Chodźki w Lublinie / Witold Chodźko Institute of Rural Health in Lublin, Lublin, Poland (Zakład Biologii Medycznej i Badań Translacyjnych / Department of Molecular Biology and Translational Research).
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Transliterated Title :
Odpady cytostatyczne i cytotoksyczne – zasady postępowania w Polsce.
Źródło :
Medycyna pracy [Med Pr] 2019 Jun 14; Vol. 70 (3), pp. 377-391. Date of Electronic Publication: 2019 May 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents*
Chemical Safety*
Cytostatic Agents*
Cytotoxins*
Medical Waste Disposal*
Health Personnel ; Humans ; Poland
Czasopismo naukowe
Tytuł :
Guanosine Nucleolipids: Synthesis, Characterization, Aggregation and X-Ray Crystallographic Identification of Electricity-Conducting G-Ribbons.
Autorzy :
Reuter H; Anorganische Chemie II, Strukturchemie, Institute of Chemistry of New Materials, University of Osnabrück, Barbarastrasse 7, DE-49069, Osnabrück, Germany.
van Bodegraven AM; Organic Chemistry I - Bioorganic Chemistry, Institute of Chemistry of New Materials, University of Osnabrück, Barbarastrasse 7, DE-49069, Osnabrück, Germany.
Bender E; Organic Chemistry I - Bioorganic Chemistry, Institute of Chemistry of New Materials, University of Osnabrück, Barbarastrasse 7, DE-49069, Osnabrück, Germany.
Knies C; Organic Chemistry I - Bioorganic Chemistry, Institute of Chemistry of New Materials, University of Osnabrück, Barbarastrasse 7, DE-49069, Osnabrück, Germany.
Diek N; Organic Chemistry I - Organic Materials Chemistry, Institute of Chemistry of New Materials, University of Osnabrück, Barbarastrasse 7, DE-49069, Osnabrück, Germany.
Beginn U; Organic Chemistry I - Organic Materials Chemistry, Institute of Chemistry of New Materials, University of Osnabrück, Barbarastrasse 7, DE-49069, Osnabrück, Germany.
Hammerbacher K; Anatomy and Cell Biology, Department of Medical Cell Biology, Philipps-, University of Marburg, Robert-Koch-Strasse 8, DE-35032, Marburg, Germany.
Schneider V; Anatomy and Cell Biology, Department of Medical Cell Biology, Philipps-, University of Marburg, Robert-Koch-Strasse 8, DE-35032, Marburg, Germany.
Kinscherf R; Anatomy and Cell Biology, Department of Medical Cell Biology, Philipps-, University of Marburg, Robert-Koch-Strasse 8, DE-35032, Marburg, Germany.
Bonaterra GA; Anatomy and Cell Biology, Department of Medical Cell Biology, Philipps-, University of Marburg, Robert-Koch-Strasse 8, DE-35032, Marburg, Germany.
Svajda R; Department of Physics, Workshop for Electronics/IT, University of Osnabrück, Barbarastrasse 7, DE-49069, Osnabrück, Germany.
Rosemeyer H; Organic Chemistry I - Bioorganic Chemistry, Institute of Chemistry of New Materials, University of Osnabrück, Barbarastrasse 7, DE-49069, Osnabrück, Germany.
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2019 May; Vol. 16 (5), pp. e1900024. Date of Electronic Publication: 2019 May 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cytostatic Agents/*chemical synthesis
Guanosine/*chemistry
Lipids/*chemistry
Animals ; Calorimetry, Differential Scanning ; Cell Line, Tumor ; Cell Survival/drug effects ; Crystallography, X-Ray ; Cytostatic Agents/chemistry ; Cytostatic Agents/pharmacology ; Electricity ; Humans ; Hydrogen Bonding ; Lipids/chemical synthesis ; Lipids/pharmacology ; Magnetic Resonance Spectroscopy ; Molecular Conformation ; Rats ; Spectrometry, Mass, Electrospray Ionization
Czasopismo naukowe
Tytuł :
Occupational exposure to cytostatic fumes during hyperthermic intraperitoneal chemotherapy.
Autorzy :
Wiszniewska M; Department of Occupational Diseases and Environmental Health, Nofer Institute of Occupational Medicine, Lodz, Poland.
Książek A; Department of Occupational Diseases and Environmental Health, Nofer Institute of Occupational Medicine, Lodz, Poland.
Lipińska-Ojrzanowska A; Department of Occupational Diseases and Environmental Health, Nofer Institute of Occupational Medicine, Lodz, Poland.
Walusiak-Skorupa J; Department of Occupational Diseases and Environmental Health, Nofer Institute of Occupational Medicine, Lodz, Poland.
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Źródło :
Occupational medicine (Oxford, England) [Occup Med (Lond)] 2020 Jun 20; Vol. 70 (4), pp. 286-288.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Anemia, Aplastic/*chemically induced
Cytostatic Agents/*adverse effects
Hyperthermia, Induced/*nursing
Occupational Diseases/*chemically induced
Occupational Exposure/*adverse effects
Adult ; Female ; Humans
Czasopismo naukowe
Tytuł :
Ecotoxicity risk of presence of two cytostatic drugs: Bleomycin and vincristine and their binary mixture in aquatic environment.
Autorzy :
Jureczko M; Environmental Biotechnology Department, Faculty of Energy and Environmental Engineering, The Silesian University of Technology, Akademicka 2 A Str., 44-100 Gliwice, Poland. Electronic address: .
Przystaś W; Environmental Biotechnology Department, Faculty of Energy and Environmental Engineering, The Silesian University of Technology, Akademicka 2 A Str., 44-100 Gliwice, Poland; The Biotechnology Centre, The Silesian University of Technology, Krzywoustego 8 St., 44-100 Gliwice, Poland. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2019 May 15; Vol. 172, pp. 210-215. Date of Electronic Publication: 2019 Jan 30.
Typ publikacji :
Journal Article
MeSH Terms :
Araceae/*drug effects
Bleomycin/*toxicity
Cytostatic Agents/*toxicity
Daphnia/*drug effects
Pseudomonas putida/*drug effects
Vincristine/*toxicity
Water Pollutants, Chemical/*toxicity
Animals ; Biodegradation, Environmental ; Bleomycin/chemistry ; Cytostatic Agents/chemistry ; Food Chain ; Fresh Water/chemistry ; Risk Assessment ; Toxicity Tests, Acute ; Vincristine/chemistry ; Waste Water/chemistry ; Water Purification
Czasopismo naukowe
Tytuł :
Dipeptidyl nitrile derivatives have cytostatic effects against Leishmania spp. promastigotes.
Autorzy :
Quilles JC Jr; Medicinal Chemistry Group (NEQUIMED), São Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), Av. Trabalhador São-carlense, 400, São Carlos, SP, 13.566-590, Brazil. Electronic address: .
Tezuka DY; Medicinal Chemistry Group (NEQUIMED), São Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), Av. Trabalhador São-carlense, 400, São Carlos, SP, 13.566-590, Brazil; Programa de Pós-graduação em Bioengenharia, University of São Paulo (USP), Av. Trabalhador São-carlense, 400, São Carlos, SP, Brazil. Electronic address: .
Lopes CD; Medicinal Chemistry Group (NEQUIMED), São Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), Av. Trabalhador São-carlense, 400, São Carlos, SP, 13.566-590, Brazil; Programa de Pós-graduação em Bioengenharia, University of São Paulo (USP), Av. Trabalhador São-carlense, 400, São Carlos, SP, Brazil. Electronic address: .
Ribeiro FL; Medicinal Chemistry Group (NEQUIMED), São Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), Av. Trabalhador São-carlense, 400, São Carlos, SP, 13.566-590, Brazil. Electronic address: .
Laughton CA; School of Pharmacy and Centre for Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD, UK. Electronic address: .
de Albuquerque S; Laboratório de Parasitologia, Falculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP-USP), Ribeirão Preto, SP, Brazil. Electronic address: .
Montanari CA; Medicinal Chemistry Group (NEQUIMED), São Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), Av. Trabalhador São-carlense, 400, São Carlos, SP, 13.566-590, Brazil. Electronic address: .
Leitão A; Medicinal Chemistry Group (NEQUIMED), São Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), Av. Trabalhador São-carlense, 400, São Carlos, SP, 13.566-590, Brazil. Electronic address: .
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Źródło :
Experimental parasitology [Exp Parasitol] 2019 May; Vol. 200, pp. 84-91. Date of Electronic Publication: 2019 Apr 05.
Typ publikacji :
Journal Article
MeSH Terms :
Antiprotozoal Agents/*pharmacology
Cysteine Proteinase Inhibitors/*pharmacology
Cytostatic Agents/*pharmacology
Leishmania infantum/*drug effects
Leishmania mexicana/*drug effects
Nitriles/*pharmacology
Animals ; Antiprotozoal Agents/chemistry ; Cell Line ; Cysteine Proteinase Inhibitors/chemistry ; Cytostatic Agents/chemistry ; Fibroblasts/drug effects ; Flow Cytometry ; Leishmania infantum/enzymology ; Leishmania mexicana/enzymology ; Macrophages/drug effects ; Mice ; Nitriles/chemistry
Czasopismo naukowe
Tytuł :
Binding of BRACO19 to a Telomeric G-Quadruplex DNA Probed by All-Atom Molecular Dynamics Simulations with Explicit Solvent.
Autorzy :
Machireddy B; College of Science and Mathematics, Rowan University, Glassboro, NJ 08028, USA. .
Sullivan HJ; College of Science and Mathematics, Rowan University, Glassboro, NJ 08028, USA. .
Wu C; College of Science and Mathematics, Rowan University, Glassboro, NJ 08028, USA. .
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2019 Mar 13; Vol. 24 (6). Date of Electronic Publication: 2019 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Acridines/*pharmacology
Cytostatic Agents/*pharmacology
DNA/*chemistry
DNA/*metabolism
Acridines/chemistry ; Binding Sites ; Cell Line, Tumor ; Cytostatic Agents/chemistry ; G-Quadruplexes ; Humans ; Models, Molecular ; Molecular Dynamics Simulation ; Nucleic Acid Conformation ; Solvents/chemistry
Czasopismo naukowe
Tytuł :
Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate.
Autorzy :
Gaugaz FZ; ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, 8093 Zürich, Switzerland. .
Chicca A; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland. .
Redondo-Horcajo M; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. .
Barasoain I; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. .
Díaz JF; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. .
Altmann KH; ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, 8093 Zürich, Switzerland. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Mar 05; Vol. 20 (5). Date of Electronic Publication: 2019 Mar 05.
Typ publikacji :
Journal Article
MeSH Terms :
Cytostatic Agents/*chemical synthesis
Epothilones/*pharmacology
Microtubules/*metabolism
Peptides/*pharmacology
Tubulin Modulators/*chemical synthesis
Animals ; Cattle ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cytostatic Agents/pharmacology ; Epothilones/chemistry ; ErbB Receptors/metabolism ; HEK293 Cells ; Humans ; Peptides/chemistry ; Tubulin/metabolism ; Tubulin Modulators/pharmacology
Czasopismo naukowe
Tytuł :
Targeting a major hub of cell fate decisions - the mitochondrial-associated membrane.
Autorzy :
Carroll WL; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU-Langone Medical Center, New York, NY, USA.
Evensen NA; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU-Langone Medical Center, New York, NY, USA.
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Źródło :
Haematologica [Haematologica] 2019 Mar; Vol. 104 (3), pp. 419-421.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Cytostatic Agents*
Leukemia*
Cell Differentiation ; Endoplasmic Reticulum ; Humans ; Mitochondria/drug effects
Opinia redakcyjna

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