Skocz do pozycji: 1.

Tytuł:

Hybrid Peptide-Alkoxyamine Drugs: A Strategy for the Development of a New Family of Antiplasmodial Drugs.

Autorzy:

Embo-Ibouanga AW; Aix-Marseille University, CNRS, UMR 7273, 13007 Marseille, France.
Nguyen M; LCC-CNRS, Laboratoire de Chimie de Coordination and MAAP, New Antimalarial Molecules and Pharmacological Approaches, Inserm ERL 1289, Université de Toulouse, CNRS, 31077 Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III-Paul Sabatier (UPS), 31077 Toulouse, France.
Paloque L; LCC-CNRS, Laboratoire de Chimie de Coordination and MAAP, New Antimalarial Molecules and Pharmacological Approaches, Inserm ERL 1289, Université de Toulouse, CNRS, 31077 Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III-Paul Sabatier (UPS), 31077 Toulouse, France.
Coustets M; LCC-CNRS, Laboratoire de Chimie de Coordination and MAAP, New Antimalarial Molecules and Pharmacological Approaches, Inserm ERL 1289, Université de Toulouse, CNRS, 31077 Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III-Paul Sabatier (UPS), 31077 Toulouse, France.
Joly JP; Aix-Marseille University, CNRS, UMR 7273, 13007 Marseille, France.
Augereau JM; LCC-CNRS, Laboratoire de Chimie de Coordination and MAAP, New Antimalarial Molecules and Pharmacological Approaches, Inserm ERL 1289, Université de Toulouse, CNRS, 31077 Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III-Paul Sabatier (UPS), 31077 Toulouse, France.
Vanthuyne N; Aix-Marseille University, CNRS, Centrale Marseille ISM2 Marseille, 13007 Marseille, France.
Bikanga R; Université des Sciences et Techniques de Masuku, LASNSOM, BP 901 Franceville, Gabon.
Coquin N; LCC-CNRS, Laboratoire de Chimie de Coordination and MAAP, New Antimalarial Molecules and Pharmacological Approaches, Inserm ERL 1289, Université de Toulouse, CNRS, 31077 Toulouse, France.
Robert A; LCC-CNRS, Laboratoire de Chimie de Coordination and MAAP, New Antimalarial Molecules and Pharmacological Approaches, Inserm ERL 1289, Université de Toulouse, CNRS, 31077 Toulouse, France.
Audran G; Aix-Marseille University, CNRS, UMR 7273, 13007 Marseille, France.
Boissier J; IHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 66860 Perpignan, France.
Mellet P; Magnetic Resonance of Biological Systems, UMR 5536 CNRS-University of Bordeaux, 33076 Bordeaux, France.; INSERM, 33076 Bordeaux, France.
Benoit-Vical F; LCC-CNRS, Laboratoire de Chimie de Coordination and MAAP, New Antimalarial Molecules and Pharmacological Approaches, Inserm ERL 1289, Université de Toulouse, CNRS, 31077 Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III-Paul Sabatier (UPS), 31077 Toulouse, France.
Marque SRA; Aix-Marseille University, CNRS, UMR 7273, 13007 Marseille, France.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2024 Mar 21; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 21.

Typ publikacji:

Journal Article

MeSH Terms:

Antimalarials*/chemistry
Cytostatic Agents*/therapeutic use
Malaria*/drug therapy
Malaria, Falciparum*/drug therapy
Humans ; Plasmodium falciparum ; Peptides/pharmacology ; Peptides/therapeutic use

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 2.

Tytuł:

The strain-dependent cytostatic activity of Lactococcus lactis on CRC cell lines is mediated through the release of arginine deiminase.

Autorzy:

Jastrząb R; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Adolfa Pawińskiego 5A, Warsaw, 02-106, Poland.; Olimp Laboratories, Pustynia 84F, Debica, 39-200, Poland.
Tomecki R; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Adolfa Pawińskiego 5A, Warsaw, 02-106, Poland.; Faculty of Biology, University of Warsaw, Miecznikowa 1, Warsaw, 02-089, Poland.
Jurkiewicz A; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Adolfa Pawińskiego 5A, Warsaw, 02-106, Poland.
Graczyk D; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Adolfa Pawińskiego 5A, Warsaw, 02-106, Poland.
Szczepankowska AK; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Adolfa Pawińskiego 5A, Warsaw, 02-106, Poland.
Mytych J; Olimp Laboratories, Pustynia 84F, Debica, 39-200, Poland.
Wolman D; Olimp Laboratories, Pustynia 84F, Debica, 39-200, Poland.
Siedlecki P; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Adolfa Pawińskiego 5A, Warsaw, 02-106, Poland. .

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Źródło:

Microbial cell factories [Microb Cell Fact] 2024 Mar 14; Vol. 23 (1), pp. 82. Date of Electronic Publication: 2024 Mar 14.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*/metabolism
Lactococcus lactis*/metabolism
Humans ; Hydrolases/metabolism ; Cell Line, Tumor ; Arginine

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 3.

Tytuł:

Inhibition of Multifunctional Protein p32/C1QBP Promotes Cytostatic Effects in Colon Cancer Cells by Altering Mitogenic Signaling Pathways and Promoting Mitochondrial Damage.

Autorzy:

Egusquiza-Alvarez CA; Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City 04510, Mexico.
Moreno-Londoño AP; Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City 04510, Mexico.
Alvarado-Ortiz E; Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City 04510, Mexico.
Ramos-Godínez MDP; Departamento de Microscopía Electrónica, Instituto Nacional de Cancerología, Secretaría de Salud, Mexico City 14080, Mexico.
Sarabia-Sánchez MA; Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City 04510, Mexico.
Castañeda-Patlán MC; Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City 04510, Mexico.
Robles-Flores M; Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City 04510, Mexico.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2024 Feb 27; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 27.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*/pharmacology
Colonic Neoplasms*
Humans ; Mitogens/pharmacology ; Signal Transduction ; Mitochondrial Proteins/metabolism ; Cell Proliferation ; Carrier Proteins/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 4.

Tytuł:

Involvement of the tumour necrosis factor receptor system in glioblastoma cell death induced by palbociclib-heptamethine cyanine dye conjugate.

Autorzy:

Cooper E; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Oyagawa CRM; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Johnson R; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Choi PJ; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Foliaki JM; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Correia J; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Neurosurgery, Auckland City Hospital, Private Bag 92024, Auckland, 1142, New Zealand.
Schweder P; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Neurosurgery, Auckland City Hospital, Private Bag 92024, Auckland, 1142, New Zealand.
Heppner P; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Neurosurgery, Auckland City Hospital, Private Bag 92024, Auckland, 1142, New Zealand.
Mee E; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Neurosurgery, Auckland City Hospital, Private Bag 92024, Auckland, 1142, New Zealand.
Turner C; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Anatomical Pathology, Auckland City Hospital, 2 Park Road, LabPlus, Auckland, New Zealand.
Faull R; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Denny WA; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Dragunow M; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. .; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. .
Jose J; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. .
Park TI; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. .; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. .

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Źródło:

Cell communication and signaling : CCS [Cell Commun Signal] 2024 Jan 11; Vol. 22 (1), pp. 30. Date of Electronic Publication: 2024 Jan 11.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media

MeSH Terms:

Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Carbocyanines*
Cytostatic Agents*/pharmacology
Cytostatic Agents*/therapeutic use
Glioblastoma*/drug therapy
Glioblastoma*/metabolism
Indoles*
Piperazines*
Pyridines*
Humans ; Apoptosis ; Cell Line, Tumor ; Receptors, Tumor Necrosis Factor/physiology ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Tumor Microenvironment ; Tumor Necrosis Factor-alpha/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 5.

Tytuł:

Protocol of the IntenSify-Trial: An open-label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab-paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy.

Autorzy:

Hohmann N; Department of Medical Oncology, Heidelberg University Hospital, National Center for Tumor Diseases, Heidelberg, Germany.
Sprick MR; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.
Pohl M; Institute of Medical Biometry, University Hospital Heidelberg, Heidelberg, Germany.
Ahmed A; Department of Medical Oncology, Heidelberg University Hospital, National Center for Tumor Diseases, Heidelberg, Germany.
Burhenne J; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.
Kirchner M; Institute of Medical Biometry, University Hospital Heidelberg, Heidelberg, Germany.
Le Cornet L; NCT Trial Center, NCT, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kratzmann M; NCT Trial Center, NCT, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Hajda J; Pharmacovigilance Department, Coordination Centre for Clinical Trials (KKS), Heidelberg University Hospital, Heidelberg, Germany.
Stenzinger A; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Steindorf K; Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany.
Delorme S; Division of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Schlemmer HP; Division of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Riethdorf S; Institute of Tumor Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
van Schaik R; Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.
Pantel K; Institute of Tumor Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Siveke J; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK Partner Site Essen) and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Seufferlein T; Department of Internal Medicine I, Ulm University Hospital, Ulm, Germany.
Jäger D; Department of Medical Oncology, Heidelberg University Hospital, National Center for Tumor Diseases, Heidelberg, Germany.; Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Haefeli WE; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.
Trumpp A; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.
Springfeld C; Department of Medical Oncology, Heidelberg University Hospital, National Center for Tumor Diseases, Heidelberg, Germany.

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Źródło:

Clinical and translational science [Clin Transl Sci] 2023 Dec; Vol. 16 (12), pp. 2483-2493. Date of Electronic Publication: 2023 Nov 03.

Typ publikacji:

Clinical Trial Protocol; Journal Article

MeSH Terms:

Cytostatic Agents*/therapeutic use
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/pathology
Carcinoma, Pancreatic Ductal*/drug therapy
Carcinoma, Pancreatic Ductal*/pathology
Humans ; Gemcitabine ; Cytochrome P-450 CYP3A ; Cytochrome P-450 CYP3A Inhibitors ; Deoxycytidine/adverse effects ; Cobicistat ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Paclitaxel/adverse effects ; Clinical Trials, Phase I as Topic

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 6.

Tytuł:

The role of neuromuscular ultrasound in diagnostics of peripheral neuropathies induced by cytostatic agents or immunotherapies.

Autorzy:

Hartinger S; Department of Neurology, Jena University Hospital, Friedrich Schiller University Jena, Am Klinikum 1, 07747, Jena, Germany. .; Neurooncological Center, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany. .
Hammersen J; Klinik für Innere Medizin II, Hämatologie, Internistische Onkologie und Palliativmedizin, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, Jena, Deutschland.
Leistner NA; Department of Neurology, Jena University Hospital, Friedrich Schiller University Jena, Am Klinikum 1, 07747, Jena, Germany.
Lawson McLean A; Neurooncological Center, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.; Department of Neurosurgery, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.
Risse C; Department of Neurology, Jena University Hospital, Friedrich Schiller University Jena, Am Klinikum 1, 07747, Jena, Germany.
Senft C; Neurooncological Center, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.; Department of Neurosurgery, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.
Schütze S; Department of Gynecology and Reproductive Medicine, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.
Heiling B; Department of Neurology, Jena University Hospital, Friedrich Schiller University Jena, Am Klinikum 1, 07747, Jena, Germany.
Schwab M; Department of Neurology, Jena University Hospital, Friedrich Schiller University Jena, Am Klinikum 1, 07747, Jena, Germany.
Mäurer I; Department of Neurology, Jena University Hospital, Friedrich Schiller University Jena, Am Klinikum 1, 07747, Jena, Germany.; Neurooncological Center, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.

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Źródło:

Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Nov 27; Vol. 11 (1), pp. 187. Date of Electronic Publication: 2023 Nov 27.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Peripheral Nervous System Diseases*/chemically induced
Peripheral Nervous System Diseases*/diagnostic imaging
Cytostatic Agents*/adverse effects
Antineoplastic Agents*/toxicity
Neurotoxicity Syndromes*
Humans ; Prospective Studies ; Immunotherapy/adverse effects

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 7.

Tytuł:

New Steroidal Selenides as Proapoptotic Factors.

Autorzy:

Jastrzebska I; Faculty of Chemistry, University of Białystok, Ciołkowskiego 1K, 15-245 Białystok, Poland.
Wawrusiewicz-Kurylonek N; Department of Clinical Genetics, Medical University of Białystok, Waszyngtona 13, 15-089 Białystok, Poland.
Grześ PA; Faculty of Chemistry, University of Białystok, Ciołkowskiego 1K, 15-245 Białystok, Poland.
Ratkiewicz A; Faculty of Chemistry, University of Białystok, Ciołkowskiego 1K, 15-245 Białystok, Poland.
Grabowska E; Doctoral School of Exact and Natural Sciences, University of Bialystok, K. Ciolkowskiego 1K, 15-245 Bialystok, Poland.
Czerniecka M; Faculty of Biology, University of Białystok, Ciołkowskiego 1J, 15-245 Białystok, Poland.
Czyżewska U; Faculty of Biology, University of Białystok, Ciołkowskiego 1J, 15-245 Białystok, Poland.
Tylicki A; Faculty of Biology, University of Białystok, Ciołkowskiego 1J, 15-245 Białystok, Poland.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Nov 10; Vol. 28 (22). Date of Electronic Publication: 2023 Nov 10.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*/pharmacology
Humans ; HeLa Cells ; Apoptosis ; Cholesterol/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 8.

Tytuł:

Characteristics of Microparticles Based on Resorbable Polyhydroxyalkanoates Loaded with Antibacterial and Cytostatic Drugs.

Autorzy:

Murueva AV; Institute of Biophysics SB RAS, Federal Research Center 'Krasnoyarsk Science Center SB RAS' (IBP SB RAS), 50/50 Akademgorodok, 660036 Krasnoyarsk, Russia.; Institute of Fundamental Biology and Biotechnology, Siberian Federal University, 79 Svobodny Pr., 660041 Krasnoyarsk, Russia.
Shershneva AM; Institute of Fundamental Biology and Biotechnology, Siberian Federal University, 79 Svobodny Pr., 660041 Krasnoyarsk, Russia.
Shishatskaya EI; Institute of Biophysics SB RAS, Federal Research Center 'Krasnoyarsk Science Center SB RAS' (IBP SB RAS), 50/50 Akademgorodok, 660036 Krasnoyarsk, Russia.; Institute of Fundamental Biology and Biotechnology, Siberian Federal University, 79 Svobodny Pr., 660041 Krasnoyarsk, Russia.; Chemistry Engineering Centre, ITMO University, Kronverkskiy Prospekt, 49A, 197101 Saint Petersburg, Russia.
Volova TG; Institute of Biophysics SB RAS, Federal Research Center 'Krasnoyarsk Science Center SB RAS' (IBP SB RAS), 50/50 Akademgorodok, 660036 Krasnoyarsk, Russia.; Institute of Fundamental Biology and Biotechnology, Siberian Federal University, 79 Svobodny Pr., 660041 Krasnoyarsk, Russia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Oct 07; Vol. 24 (19). Date of Electronic Publication: 2023 Oct 07.

Typ publikacji:

Journal Article

MeSH Terms:

Polyhydroxyalkanoates*
Cytostatic Agents*
Escherichia coli ; Drug Delivery Systems ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Particle Size

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 9.

Tytuł:

Cytoprotective, Cytotoxic and Cytostatic Roles of Autophagy in Response to BET Inhibitors.

Autorzy:

Elshazly AM; Department of Pharmacology and Toxicology, Massey Cancer Center, Virginia Commonwealth University, 401 College St., Richmond, VA 23298, USA.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Gewirtz DA; Department of Pharmacology and Toxicology, Massey Cancer Center, Virginia Commonwealth University, 401 College St., Richmond, VA 23298, USA.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Aug 11; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 11.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Cytostatic Agents*
Antineoplastic Agents*/pharmacology
Animals ; Nuclear Proteins ; Transcription Factors ; Autophagy

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 10.

Tytuł:

Identification of Bacterial Metabolites Modulating Breast Cancer Cell Proliferation and Epithelial-Mesenchymal Transition.

Autorzy:

Ujlaki G; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Kovács T; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Vida A; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Kókai E; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Rauch B; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Schwarcz S; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Mikó E; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Janka E; Department of Dermatology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Sipos A; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Hegedűs C; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Uray K; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Nagy P; Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Bai P; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; MTA-DE Lendület Laboratory of Cellular Metabolism, 4032 Debrecen, Hungary.; Research Center for Molecular Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; ELKH-DE Cell Biology and Signaling Research Group ELKH, 4032 Debrecen, Hungary.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Aug 05; Vol. 28 (15). Date of Electronic Publication: 2023 Aug 05.

Typ publikacji:

Journal Article

MeSH Terms:

Breast Neoplasms*/drug therapy
Breast Neoplasms*/metabolism
Cytostatic Agents*/pharmacology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Animals ; Mice ; Female ; Epithelial-Mesenchymal Transition ; Butyric Acid/pharmacology ; Cell Line, Tumor ; Cell Proliferation

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 11.

Tytuł:

Functionalization of Octacalcium Phosphate Bone Graft with Cisplatin and Zoledronic Acid: Physicochemical and Bioactive Properties.

Autorzy:

Kuvshinova EA; P.A. Herzen Moscow Research Oncology Institute, Branch of FSBI National Medical Research Radiological Centre, Ministry of Health of the Russian Federation, 2nd Botkinsky Pass. 3, 125284 Moscow, Russia.
Petrakova NV; A.A. Baikov Institute of Metallurgy and Materials Science RAS, Leninsky Avenue 49, 119334 Moscow, Russia.
Nikitina YO; A.A. Baikov Institute of Metallurgy and Materials Science RAS, Leninsky Avenue 49, 119334 Moscow, Russia.
Sviridova IK; P.A. Herzen Moscow Research Oncology Institute, Branch of FSBI National Medical Research Radiological Centre, Ministry of Health of the Russian Federation, 2nd Botkinsky Pass. 3, 125284 Moscow, Russia.
Akhmedova SA; P.A. Herzen Moscow Research Oncology Institute, Branch of FSBI National Medical Research Radiological Centre, Ministry of Health of the Russian Federation, 2nd Botkinsky Pass. 3, 125284 Moscow, Russia.
Kirsanova VA; P.A. Herzen Moscow Research Oncology Institute, Branch of FSBI National Medical Research Radiological Centre, Ministry of Health of the Russian Federation, 2nd Botkinsky Pass. 3, 125284 Moscow, Russia.
Karalkin PA; P.A. Herzen Moscow Research Oncology Institute, Branch of FSBI National Medical Research Radiological Centre, Ministry of Health of the Russian Federation, 2nd Botkinsky Pass. 3, 125284 Moscow, Russia.; L.L. Levshin Institute of Cluster Oncology, I.M. Sechenov First Moscow State Medical University, Trubetskaya 8-2, 119991 Moscow, Russia.
Komlev VS; A.A. Baikov Institute of Metallurgy and Materials Science RAS, Leninsky Avenue 49, 119334 Moscow, Russia.
Sergeeva NS; P.A. Herzen Moscow Research Oncology Institute, Branch of FSBI National Medical Research Radiological Centre, Ministry of Health of the Russian Federation, 2nd Botkinsky Pass. 3, 125284 Moscow, Russia.
Kaprin AD; FSBI National Medical Research Radiological Centre, Ministry of Health of the Russian Federation, 2nd Botkinsky Pass. 3, 125284 Moscow, Russia.; Department of Urology and Operative Nephrology, Peoples' Friendship University of Russia, Miklukho-Maklay Str., 6, 117198 Moscow, Russia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Jul 19; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 19.

Typ publikacji:

Journal Article

MeSH Terms:

Cisplatin*/pharmacology
Cytostatic Agents*
Male ; Animals ; Zoledronic Acid/pharmacology ; Calcium Phosphates/chemistry ; Bone Regeneration

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 12.

Tytuł:

Daphnetin, a Coumarin with Anticancer Potential against Human Melanoma: In Vitro Study of Its Effective Combination with Selected Cytostatic Drugs.

Autorzy:

Wróblewska-Łuczka P; Department of Occupational Medicine, Medical University of Lublin, ul. Jaczewskiego 8b, 20-090 Lublin, Poland.
Góralczyk A; Department of Occupational Medicine, Medical University of Lublin, ul. Jaczewskiego 8b, 20-090 Lublin, Poland.
Łuszczki JJ; Department of Occupational Medicine, Medical University of Lublin, ul. Jaczewskiego 8b, 20-090 Lublin, Poland.

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Źródło:

Cells [Cells] 2023 Jun 09; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 09.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Cytostatic Agents*/pharmacology
Melanoma*/drug therapy
Humans ; Vemurafenib/therapeutic use ; Docetaxel/pharmacology ; Docetaxel/therapeutic use ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Mitoxantrone/therapeutic use ; Epirubicin ; Coumarins/pharmacology ; Melanoma, Cutaneous Malignant

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 13.

Tytuł:

Enhancing the Impact of Chemotherapy on Ewing Sarcoma Cells through Combination with Cold Physical Plasma.

Autorzy:

Nitsch A; Center for Orthopedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, Germany.
Qarqash S; Center for Orthopedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, Germany.
Römer S; Department of General Pharmacology, Institute of Pharmacology, Center of Drug Absorption and Transport (C_DAT), University Medicine Greifswald, 17487 Greifswald, Germany.
Schoon J; Center for Orthopedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, Germany.
Ekkernkamp A; Center for Orthopedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, Germany.; Department of Trauma and Orthopaedic Surgery, BG Klinikum Unfallkrankenhaus Berlin, Warener Straße 7, 12683 Berlin, Germany.
Niethard M; Center for Orthopedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, Germany.; Sarcoma Centre, HELIOS-Klinikum Berlin-Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany.
Reichert JC; Center for Orthopedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, Germany.
Wassilew GI; Center for Orthopedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, Germany.
Tzvetkov MV; Department of General Pharmacology, Institute of Pharmacology, Center of Drug Absorption and Transport (C_DAT), University Medicine Greifswald, 17487 Greifswald, Germany.
Haralambiev L; Center for Orthopedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, Germany.; Department of Trauma and Orthopaedic Surgery, BG Klinikum Unfallkrankenhaus Berlin, Warener Straße 7, 12683 Berlin, Germany.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 May 12; Vol. 24 (10). Date of Electronic Publication: 2023 May 12.

Typ publikacji:

Journal Article

MeSH Terms:

Sarcoma, Ewing*/pathology
Cytostatic Agents*/therapeutic use
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Bone Neoplasms*/metabolism
Child ; Humans ; Vincristine/pharmacology ; Vincristine/therapeutic use ; Doxorubicin/therapeutic use ; Cell Line, Tumor

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 14.

Tytuł:

Synergy, Additivity and Antagonism between Esculetin and Six Commonly Used Chemotherapeutics in Various Malignant Melanoma Cell Lines-An Isobolographic Analysis.

Autorzy:

Wróblewska-Łuczka P; Department of Occupational Medicine, Medical University of Lublin, ul. Jaczewskiego 8b, 20-090 Lublin, Poland.
Góralczyk A; Department of Occupational Medicine, Medical University of Lublin, ul. Jaczewskiego 8b, 20-090 Lublin, Poland.
Łuszczki JJ; Department of Occupational Medicine, Medical University of Lublin, ul. Jaczewskiego 8b, 20-090 Lublin, Poland.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 May 05; Vol. 28 (9). Date of Electronic Publication: 2023 May 05.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*
Melanoma*/drug therapy
Humans ; Cisplatin/pharmacology ; Docetaxel ; Epirubicin/pharmacology ; Vemurafenib ; Mitoxantrone ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Paclitaxel/pharmacology ; Cell Line ; Cell Line, Tumor

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 15.

Tytuł:

Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling.

Autorzy:

Xu X; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Beijin Road, Guiyang 550014, China.
Deng L; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Beijin Road, Guiyang 550014, China.
Tang Y; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Beijin Road, Guiyang 550014, China.; Kunming Institute of Botany, Chinese Academy of Sciences (CAS), Kunming 650201, China.
Li J; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Beijin Road, Guiyang 550014, China.
Zhong T; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Beijin Road, Guiyang 550014, China.
Hao X; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Beijin Road, Guiyang 550014, China.; Kunming Institute of Botany, Chinese Academy of Sciences (CAS), Kunming 650201, China.
Fan Y; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Beijin Road, Guiyang 550014, China.
Mu S; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Beijin Road, Guiyang 550014, China.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Apr 30; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 30.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*/pharmacology
Leukemia, Erythroblastic, Acute*/drug therapy
Leukemia*/drug therapy
Humans ; Phosphatidylinositol 3-Kinases/metabolism ; Cyanides ; Apoptosis ; Proto-Oncogene Proteins c-akt/metabolism ; Cell Line, Tumor

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 16.

Tytuł:

Achievement of the Selectivity of Cytotoxic Agents against Cancer Cells by Creation of Combined Formulation with Terpenoid Adjuvants as Prospects to Overcome Multidrug Resistance.

Autorzy:

Zlotnikov ID; Faculty of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1/3, 119991 Moscow, Russia.
Dobryakova NV; Faculty of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1/3, 119991 Moscow, Russia.; Laboratory of Medical Biotechnology, Institute of Biomedical Chemistry, Pogodinskaya St. 10/8, 119121 Moscow, Russia.
Ezhov AA; Faculty of Physics, Lomonosov Moscow State University, Leninskie Gory 1/2, 119991 Moscow, Russia.
Kudryashova EV; Faculty of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1/3, 119991 Moscow, Russia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Apr 28; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 28.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*/pharmacology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Neoplasms*
Humans ; Terpenes/pharmacology ; Cytotoxins/pharmacology ; HEK293 Cells ; Drug Resistance, Neoplasm ; Drug Resistance, Multiple ; Doxorubicin/pharmacology ; Doxorubicin/chemistry ; Plant Extracts/pharmacology ; Adjuvants, Immunologic/pharmacology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 17.

Tytuł:

Half-Sandwich Type Platinum-Group Metal Complexes of C -Glucosaminyl Azines: Synthesis and Antineoplastic and Antimicrobial Activities.

Autorzy:

Kacsir I; Department of Organic Chemistry, University of Debrecen, P.O. Box 400, H-4002 Debrecen, Hungary.; Doctoral School of Chemistry, University of Debrecen, P.O. Box 400, H-4002 Debrecen, Hungary.
Sipos A; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Egyetem Tér 1., H-4032 Debrecen, Hungary.; The Hungarian Academy of Sciences, Center of Excellence, Hungary.; MTA-DE Cell Biology and Signaling Research Group ELKH, H-4032 Debrecen, Hungary.
Major E; Department of Metagenomics, University of Debrecen, H-4032 Debrecen, Hungary.
Bajusz N; Department of Metagenomics, University of Debrecen, H-4032 Debrecen, Hungary.
Bényei A; Department of Physical Chemistry, Faculty of Sciences and Technology, University of Debrecen, Egyetem Tér 1., H-4032 Debrecen, Hungary.
Buglyó P; Department of Inorganic & Analytical Chemistry, Faculty of Sciences and Technology, University of Debrecen, Egyetem Tér 1., H-4032 Debrecen, Hungary.
Somsák L; Department of Organic Chemistry, University of Debrecen, P.O. Box 400, H-4002 Debrecen, Hungary.
Kardos G; Department of Metagenomics, University of Debrecen, H-4032 Debrecen, Hungary.
Bai P; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Egyetem Tér 1., H-4032 Debrecen, Hungary.; The Hungarian Academy of Sciences, Center of Excellence, Hungary.; MTA-DE Cell Biology and Signaling Research Group ELKH, H-4032 Debrecen, Hungary.; NKFIH-DE Lendület Laboratory of Cellular Metabolism, H-4032 Debrecen, Hungary.; Research Center for Molecular Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Bokor É; Department of Organic Chemistry, University of Debrecen, P.O. Box 400, H-4002 Debrecen, Hungary.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Mar 29; Vol. 28 (7). Date of Electronic Publication: 2023 Mar 29.

Typ publikacji:

Journal Article

MeSH Terms:

Coordination Complexes*/chemistry
Cytostatic Agents*/therapeutic use
Ovarian Neoplasms*/drug therapy
Antineoplastic Agents*/chemistry
Quinolines*/therapeutic use
Anti-Infective Agents*/pharmacology
Anti-Infective Agents*/therapeutic use
Ruthenium*/chemistry
Humans ; Female ; Cell Line, Tumor ; Metals ; Azo Compounds/therapeutic use ; Pyridines/pharmacology ; Pyridines/therapeutic use

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 18.

Tytuł:

Influence of the Drug Position on Bioactivity in Angiopep-2-Daunomycin Conjugates.

Autorzy:

Pethő L; ELKH-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.
Oláh-Szabó R; ELKH-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.
Mező G; ELKH-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.; Institute of Chemistry, Faculty of Science, Eötvös Loránd University, 1117 Budapest, Hungary.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Feb 04; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 04.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*
Glioblastoma*/metabolism
Rats ; Animals ; Humans ; Daunorubicin/metabolism ; Peptides/chemistry ; Blood-Brain Barrier/metabolism ; Drug Delivery Systems/methods ; Cell Line, Tumor

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 19.

Tytuł:

Novel 3,9-Disubstituted Acridines with Strong Inhibition Activity against Topoisomerase I: Synthesis, Biological Evaluation and Molecular Docking Study.

Autorzy:

Krochtová K; Department of Biochemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, Moyzesova 11, 040 01 Košice, Slovakia.
Halečková A; Department of Organic Chemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, Moyzesova 11, 040 01 Košice, Slovakia.
Janovec L; Department of Organic Chemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, Moyzesova 11, 040 01 Košice, Slovakia.
Blizniaková M; Department of Biochemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, Moyzesova 11, 040 01 Košice, Slovakia.
Kušnírová K; Department of Organic Chemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, Moyzesova 11, 040 01 Košice, Slovakia.
Kožurková M; Department of Biochemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, Moyzesova 11, 040 01 Košice, Slovakia.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Jan 30; Vol. 28 (3). Date of Electronic Publication: 2023 Jan 30.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*/pharmacology
Antineoplastic Agents*/chemistry
DNA Topoisomerases, Type I/metabolism ; Molecular Docking Simulation ; Acridines/pharmacology ; Acridines/chemistry ; DNA Topoisomerases, Type II/metabolism ; Circular Dichroism ; Structure-Activity Relationship ; Topoisomerase II Inhibitors/pharmacology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 20.

Tytuł:

Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism.

Autorzy:

Cardile A; Section of Biochemistry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Strada Le Grazie, 8, 37134 Verona, Italy.
Zanrè V; Section of Biochemistry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Strada Le Grazie, 8, 37134 Verona, Italy.
Campagnari R; Section of Biochemistry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Strada Le Grazie, 8, 37134 Verona, Italy.
Asson F; Section of Biochemistry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Strada Le Grazie, 8, 37134 Verona, Italy.
Addo SS; Section of Biochemistry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Strada Le Grazie, 8, 37134 Verona, Italy.
Orlandi E; Section of Biology and Genetics, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Strada Le Grazie, 8, 37134 Verona, Italy.
Menegazzi M; Section of Biochemistry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Strada Le Grazie, 8, 37134 Verona, Italy.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Jan 09; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 09.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*/pharmacology
Melanoma*/drug therapy
Melanoma*/genetics
Melanoma*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; NF-kappa B/metabolism ; Proto-Oncogene Proteins B-raf/metabolism ; TRPC6 Cation Channel ; Cell Line ; Apoptosis ; Mitochondria/metabolism ; Cell Line, Tumor ; STAT3 Transcription Factor/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 21.

Tytuł:

Design and synthesis of novel quinazolinone-based derivatives as EGFR inhibitors with antitumor activity.

Autorzy:

Sonousi A; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Hassan RA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Osman EO; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Abdou AM; Department of Microbiology and Immunology, National Research Centre, Dokki, Giza, Egypt.
Emam SH; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

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Źródło:

Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 2644-2659.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents*/chemistry
Cytostatic Agents*/pharmacology
Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Drug Screening Assays, Antitumor ; ErbB Receptors/metabolism ; Erlotinib Hydrochloride/pharmacology ; Humans ; Molecular Structure ; Protein Kinase Inhibitors ; Quinazolinones ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 22.

Tytuł:

Inhibitory prodrug mechanism for cysteine cathepsin-targeted self-controlled drug release.

Autorzy:

van Dalen FJ; Department of Tumour Immunology and the Institute for Chemical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, Netherlands.
Verdoes M; Department of Tumour Immunology and the Institute for Chemical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, Netherlands.

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Źródło:

Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 2566-2573.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*
Prodrugs*/pharmacology
Cathepsins ; Cysteine ; Doxorubicin/pharmacology ; Drug Liberation

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 23.

Tytuł:

Comparison of Different Techniques for the Determination of Platinized Cytostatic Drugs in Urine Samples.

Autorzy:

Arenas M; Departamento de Química Analítica, Escuela Politécnica Superior, Universidad de Sevilla, C/Virgen de África 7, E-41011 Sevilla, Spain.
Martín J; Departamento de Química Analítica, Escuela Politécnica Superior, Universidad de Sevilla, C/Virgen de África 7, E-41011 Sevilla, Spain.
Santos JL; Departamento de Química Analítica, Escuela Politécnica Superior, Universidad de Sevilla, C/Virgen de África 7, E-41011 Sevilla, Spain.
Aparicio I; Departamento de Química Analítica, Escuela Politécnica Superior, Universidad de Sevilla, C/Virgen de África 7, E-41011 Sevilla, Spain.
Fernández-Sanfrancisco O; Departamento de Medicina Preventiva y Salud Pública, Facultad de Farmacia, Universidad de Granada, E-18071 Granada, Spain.; Athisa Biogeneración, c/Periodista Francisco Javier Cobos, nº18, E-18014 Granada, Spain.
Alonso E; Departamento de Química Analítica, Escuela Politécnica Superior, Universidad de Sevilla, C/Virgen de África 7, E-41011 Sevilla, Spain.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Nov 23; Vol. 27 (23). Date of Electronic Publication: 2022 Nov 23.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*
Antineoplastic Agents*
Humans ; Chromatography, Liquid/methods ; Tandem Mass Spectrometry/methods ; Cisplatin ; Chromatography, High Pressure Liquid/methods

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 24.

Tytuł:

Rational Mutagenesis in the Lid Domain of Ribokinase from E. coli Results in an Order of Magnitude Increase in Activity towards D-arabinose.

Autorzy:

Zayats EA; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Fateev IV; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Kostromina MA; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Abramchik YA; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Lykoshin DD; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Yurovskaya DO; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Timofeev VI; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Berzina MY; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Eletskaya BZ; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Konstantinova ID; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Esipov RS; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2022 Oct 19; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 19.

Typ publikacji:

Journal Article

MeSH Terms:

Arabinose*
Cytostatic Agents*
Escherichia coli/genetics ; Kinetics ; Nucleosides ; Substrate Specificity ; Mutagenesis ; Antiviral Agents

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 25.

Tytuł:

6-(Methylsulfonyl) Hexyl Isothiocyanate: A Chemopreventive Agent Inducing Autophagy in Leukemia Cell Lines.

Autorzy:

Cocchi V; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40127 Bologna, Italy.
Jávega B; Laboratory of Cytomics, Joint Research Unit CIPF-UVEG, Department of Biochemistry and Molecular Biology, University of Valencia, 46010 Valencia, Spain.
Gasperini S; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40127 Bologna, Italy.
O'Connor JE; Laboratory of Cytomics, Joint Research Unit CIPF-UVEG, Department of Biochemistry and Molecular Biology, University of Valencia, 46010 Valencia, Spain.
Lenzi M; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40127 Bologna, Italy.
Hrelia P; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40127 Bologna, Italy.

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Źródło:

Biomolecules [Biomolecules] 2022 Oct 14; Vol. 12 (10). Date of Electronic Publication: 2022 Oct 14.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*/pharmacology
Leukemia*/drug therapy
Humans ; Reactive Oxygen Species ; Isothiocyanates/pharmacology ; Autophagy ; HL-60 Cells ; Apoptosis ; Cell Line, Tumor

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 26.

Tytuł:

Perspectives for the Use of Fucoidans in Clinical Oncology.

Autorzy:

Kiselevskiy MV; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, 24 Kashirskoe Sh., Moscow 115478, Russia.; Center for Biomedical Engineering, National University of Science and Technology MISIS, Leninsky Prospect 4, Moscow 119049, Russia.
Anisimova NY; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, 24 Kashirskoe Sh., Moscow 115478, Russia.; Center for Biomedical Engineering, National University of Science and Technology MISIS, Leninsky Prospect 4, Moscow 119049, Russia.
Ustyuzhanina NE; N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Av., 47, Moscow 119991, Russia.
Vinnitskiy DZ; N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Av., 47, Moscow 119991, Russia.
Tokatly AI; N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Av., 47, Moscow 119991, Russia.
Reshetnikova VV; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, 24 Kashirskoe Sh., Moscow 115478, Russia.
Chikileva IO; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, 24 Kashirskoe Sh., Moscow 115478, Russia.
Shubina IZ; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, 24 Kashirskoe Sh., Moscow 115478, Russia.
Kirgizov KI; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, 24 Kashirskoe Sh., Moscow 115478, Russia.
Nifantiev NE; N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Av., 47, Moscow 119991, Russia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2022 Oct 05; Vol. 23 (19). Date of Electronic Publication: 2022 Oct 05.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Cytostatic Agents*
Neoplasms*/drug therapy
Animals ; Anti-Inflammatory Agents ; Anticoagulants/pharmacology ; Anticoagulants/therapeutic use ; Medical Oncology ; Mice ; Polysaccharides/pharmacology ; Polysaccharides/therapeutic use ; Quality of Life

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 27.

Tytuł:

Interactions of Isoquinoline Alkaloids with Transition Metals Iron and Copper.

Autorzy:

Parvin MS; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
Chlebek J; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
Hošťálková A; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
Catapano MC; SwissBioquant, Kagenstrasse 18, 4153 Reinach, Switzerland.
Lomozová Z; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
Macáková K; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
Mladěnka P; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Sep 29; Vol. 27 (19). Date of Electronic Publication: 2022 Sep 29.

Typ publikacji:

Journal Article

MeSH Terms:

Alzheimer Disease*
Cytostatic Agents*
Chelating Agents/chemistry ; Copper/chemistry ; Dimethyl Sulfoxide ; Galantamine ; Humans ; Hydroxyl Radical ; Iron/chemistry ; Isoquinolines/pharmacology ; Reactive Oxygen Species ; Reducing Agents ; Salts

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 28.

Tytuł:

Highly Branched Betulin Based Polyanhydrides for Self-Assembled Micellar Nanoparticles Formulation.

Autorzy:

Niewolik D; Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, M. Strzody 9, 44-100 Gliwice, Poland.
Bednarczyk-Cwynar B; Department of Organic Chemistry, Poznan University of Medical Science, Grunwaldzka 6, 60-780 Poznan, Poland.
Ruszkowski P; Department of Pharmacology, Poznan University of Medical Science, Rokietnicka 3, 60-806 Poznan, Poland.
Dzido G; Department of Chemical Engineering and Process Design, Silesian University of Technology, M. Strzody 7, 44-100 Gliwice, Poland.
Jaszcz K; Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, M. Strzody 9, 44-100 Gliwice, Poland.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2022 Sep 28; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 28.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*
Nanoparticles*/chemistry
Polyanhydrides*
Prodrugs*
Drug Carriers/chemistry ; Micelles ; Polyethylene Glycols/chemistry ; Triterpenes ; Water

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 29.

Tytuł:

Combination Therapy Using Polyphenols: An Efficient Way to Improve Antitumoral Activity and Reduce Resistance.

Autorzy:

Vladu AF; Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, Gh Polizu St., 1-7, 010061 Bucharest, Romania.; National Centre for Micro and Nanomaterials, University Politehnica of Bucharest, Splaiul Independentei 313, 060042 Bucharest, Romania.; National Centre for Food Safety, University Politehnica of Bucharest, Splaiul Independentei 313, 060042 Bucharest, Romania.; The National Research and Development Institute for Textiles and Leather, Lucretiu Patrascanu, 030508 Bucharest, Romania.
Ficai D; National Centre for Micro and Nanomaterials, University Politehnica of Bucharest, Splaiul Independentei 313, 060042 Bucharest, Romania.; National Centre for Food Safety, University Politehnica of Bucharest, Splaiul Independentei 313, 060042 Bucharest, Romania.; Department of Inorganic Chemistry, Faculty of Chemical Engineering and Biotechnologies, Physical Chemistry and Electrochemistry, University Politehnica of Bucharest, Gh Polizu St., 1-7, 010061 Bucharest, Romania.
Ene AG; The National Research and Development Institute for Textiles and Leather, Lucretiu Patrascanu, 030508 Bucharest, Romania.
Ficai A; Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, Gh Polizu St., 1-7, 010061 Bucharest, Romania.; National Centre for Micro and Nanomaterials, University Politehnica of Bucharest, Splaiul Independentei 313, 060042 Bucharest, Romania.; National Centre for Food Safety, University Politehnica of Bucharest, Splaiul Independentei 313, 060042 Bucharest, Romania.; Academy of Romanian Scientists, Ilfov St. 3, 050042 Bucharest, Romania.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2022 Sep 06; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 06.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Breast Neoplasms*/metabolism
Catechin*/pharmacology
Catechin*/therapeutic use
Curcumin*/pharmacology
Cytostatic Agents*/therapeutic use
Liver Neoplasms*/drug therapy
Anti-Bacterial Agents/therapeutic use ; Doxorubicin/pharmacology ; Estrogen Receptor alpha ; Estrogen Receptor beta ; Estrogens/therapeutic use ; Female ; Fluorouracil/therapeutic use ; Humans ; Polyphenols/pharmacology ; Polyphenols/therapeutic use ; Receptors, Estrogen ; Resveratrol/pharmacology ; Resveratrol/therapeutic use ; beta Catenin

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 30.

Tytuł:

Halochromic Behavior and Anticancer Effect of New Synthetic Anthocyanidins Complexed with β-Cyclodextrin Derivatives.

Autorzy:

Păușescu I; Faculty of Industrial Chemistry and Environmental Engineering, University Politehnica Timișoara, C. Telbisz 6, 300001 Timișoara, Romania.
Kántor I; Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.; Faculty of Engineering, University of Pannonia, Egyetem u. 10, H-8200 Veszprém, Hungary.
Babos G; Faculty of Engineering, University of Pannonia, Egyetem u. 10, H-8200 Veszprém, Hungary.
May Z; Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.
Fodor-Kardos A; Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.; Faculty of Engineering, University of Pannonia, Egyetem u. 10, H-8200 Veszprém, Hungary.
Miskolczy Z; Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.
Biczók L; Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.
Péter F; Faculty of Industrial Chemistry and Environmental Engineering, University Politehnica Timișoara, C. Telbisz 6, 300001 Timișoara, Romania.; Research Institute for Renewable Energies, University Politehnica Timișoara, G. Muzicescu 138, 300501 Timișoara, Romania.
Medeleanu M; Faculty of Industrial Chemistry and Environmental Engineering, University Politehnica Timișoara, C. Telbisz 6, 300001 Timișoara, Romania.
Feczkó T; Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.; Faculty of Engineering, University of Pannonia, Egyetem u. 10, H-8200 Veszprém, Hungary.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2022 Jul 22; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 22.

Typ publikacji:

Journal Article

MeSH Terms:

Chalcone*
Cytostatic Agents*
Anthocyanins/chemistry ; Anthocyanins/pharmacology ; Cations ; Spectroscopy, Fourier Transform Infrared

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 31.

Tytuł:

Anticancer Activity of Amantadine and Evaluation of Its Interactions with Selected Cytostatics in Relation to Human Melanoma Cells.

Autorzy:

Krasowska D; Department of Dermatology, Venerology and Pediatric Dermatology, Medical University of Lublin, 20-090 Lublin, Poland.
Gerkowicz A; Department of Dermatology, Venerology and Pediatric Dermatology, Medical University of Lublin, 20-090 Lublin, Poland.
Wróblewska-Łuczka P; Department of Pathophysiology, Medical University of Lublin, 20-090 Lublin, Poland.
Grabarska A; Department of Biochemistry and Molecular Biology, Medical University of Lublin, 20-090 Lublin, Poland.
Załuska-Ogryzek K; Department of Pathophysiology, Medical University of Lublin, 20-090 Lublin, Poland.
Krasowska D; Department of Dermatology, Venerology and Pediatric Dermatology, Medical University of Lublin, 20-090 Lublin, Poland.
Łuszczki JJ; Department of Pathophysiology, Medical University of Lublin, 20-090 Lublin, Poland.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2022 Jul 11; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 11.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*/pharmacology
Melanoma*/metabolism
Parkinson Disease*
Amantadine/pharmacology ; Amantadine/therapeutic use ; Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Humans

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 32.

Tytuł:

Primary cold atmospheric plasma combined with low dose cisplatin as a possible adjuvant combination therapy for HNSCC cells-an in-vitro study.

Autorzy:

Brunner TF; Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, University Hospital, LMU, Munich, Germany. .
Probst FA; Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, University Hospital, LMU, Munich, Germany.
Troeltzsch M; Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, University Hospital, LMU, Munich, Germany.
Schwenk-Zieger S; Department of Otolaryngology, Head and Neck Surgery, University Hospital, LMU, Munich, Germany.
Zimmermann JL; Terraplasma GmbH, Garching, Germany.
Morfill G; Terraplasma GmbH, Garching, Germany.
Becker S; Department of Otolaryngology, Head and Neck Surgery, University Hospital, EKU , Tübingen, Germany.
Harréus U; Department of ENT/Head and Neck Surgery, Asklepios Hospital, Bad Tölz, Germany.
Welz C; HNO München Nord, Munich, Germany.

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Źródło:

Head & face medicine [Head Face Med] 2022 Jun 29; Vol. 18 (1), pp. 21. Date of Electronic Publication: 2022 Jun 29.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Carcinoma, Squamous Cell*/drug therapy
Carcinoma, Squamous Cell*/genetics
Cytostatic Agents*/therapeutic use
Head and Neck Neoplasms*/drug therapy
Plasma Gases*/pharmacology
Plasma Gases*/therapeutic use
Cell Line, Tumor ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Humans ; Squamous Cell Carcinoma of Head and Neck/drug therapy

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 33.

Tytuł:

Adjusting the neuron to astrocyte ratio with cytostatics in hippocampal cell cultures from postnatal rats: A comparison of cytarabino furanoside (AraC) and 5-fluoro-2'-deoxyuridine (FUdR).

Autorzy:

Lesslich HM; Department of Biochemistry II, Ruhr-Universität Bochum, Bochum, Germany.
Klapal L; Department of Biochemistry II, Ruhr-Universität Bochum, Bochum, Germany.
Wilke J; Department of Biochemistry II, Ruhr-Universität Bochum, Bochum, Germany.
Haak A; Nanoscopy Group, RUBION, Ruhr-Universität Bochum, Bochum, Germany.
Dietzel ID; Department of Biochemistry II, Ruhr-Universität Bochum, Bochum, Germany.

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Źródło:

PloS one [PLoS One] 2022 Mar 09; Vol. 17 (3), pp. e0265084. Date of Electronic Publication: 2022 Mar 09 (Print Publication: 2022).

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Astrocytes*/metabolism
Cytostatic Agents*/pharmacology
Animals ; Cell Culture Techniques ; Cells, Cultured ; Deoxyuridine/analogs & derivatives ; Floxuridine/pharmacology ; Hippocampus ; Neurons/metabolism ; Rats

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 34.

Tytuł:

Cell Culture Characterization of Prooxidative Chain-Transfer Agents as Novel Cytostatic Drugs.

Autorzy:

Heymans V; Evolutionary Biochemistry and Redox Medicine, Institute for Pathobiochemistry, University Medical Center of the Johannes Gutenberg University, 55128 Mainz, Germany.
Kunath S; Evolutionary Biochemistry and Redox Medicine, Institute for Pathobiochemistry, University Medical Center of the Johannes Gutenberg University, 55128 Mainz, Germany.
Hajieva P; Institute for Translational Medicine, MSH Medical School Hamburg, 20457 Hamburg, Germany.
Moosmann B; Evolutionary Biochemistry and Redox Medicine, Institute for Pathobiochemistry, University Medical Center of the Johannes Gutenberg University, 55128 Mainz, Germany.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Nov 08; Vol. 26 (21). Date of Electronic Publication: 2021 Nov 08.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents/*pharmacology
Antioxidants/*pharmacology
Coordination Complexes/*pharmacology
Cytostatic Agents/*pharmacology
Nitrogen Oxides/*pharmacology
Sulfhydryl Compounds/*pharmacology
Antineoplastic Agents/chemistry ; Antioxidants/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Coordination Complexes/chemistry ; Cytostatic Agents/chemistry ; Drug Screening Assays, Antitumor ; Humans ; Nitrogen Oxides/chemistry ; Sulfhydryl Compounds/chemistry ; Tumor Cells, Cultured

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 35.

Tytuł:

Optimisation of maintenance in delivery systems for cytostatic medicines.

Autorzy:

Carnero MC; Technical School of Industrial Engineers, University of Castilla-la Mancha, Ciudad Real, Spain. .; CEG-IST, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal. .
Gómez A; SERMAS, Madrid, Spain.

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Źródło:

BMC health services research [BMC Health Serv Res] 2021 Nov 02; Vol. 21 (1), pp. 1188. Date of Electronic Publication: 2021 Nov 02.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*
Pharmaceutical Preparations*
Decision Making ; Delivery of Health Care ; Humans ; Quality of Health Care

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 36.

Tytuł:

Recent Advances and Trends in Chemical CPP-Drug Conjugation Techniques.

Autorzy:

Gayraud F; Department of Chemistry, Institute for Biochemistry, University of Cologne, Zuelpicher str. 47a, D-50674 Cologne, Germany.
Klußmann M; Department of Chemistry, Institute for Biochemistry, University of Cologne, Zuelpicher str. 47a, D-50674 Cologne, Germany.
Neundorf I; Department of Chemistry, Institute for Biochemistry, University of Cologne, Zuelpicher str. 47a, D-50674 Cologne, Germany.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Mar 13; Vol. 26 (6). Date of Electronic Publication: 2021 Mar 13.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Cell-Penetrating Peptides/*administration & dosage
Cell-Penetrating Peptides/*chemical synthesis
Cytostatic Agents/*administration & dosage
Cytostatic Agents/*chemical synthesis
Drug Delivery Systems/*methods
Amino Acid Sequence ; Animals ; Cell Line, Tumor ; Cytostatic Agents/chemistry ; Drug Carriers/administration & dosage ; Drug Carriers/chemical synthesis ; Drug Carriers/chemistry ; Drug Delivery Systems/trends ; Humans ; Molecular Structure ; Organic Chemistry Phenomena

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 37.

Tytuł:

Inhibition of phase-1 biotransformation and cytostatic effects of diphenyleneiodonium on hepatoblastoma cell line HepG2 and a CYP3A4-overexpressing HepG2 cell clone.

Autorzy:

Schulz C; Fraunhofer Project Group PZ-Syn, Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses (IZI-BB), Potsdam, Germany, located at the Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Germany.
Jung F; Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany.
Küpper JH; Fraunhofer Project Group PZ-Syn, Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses (IZI-BB), Potsdam, Germany, located at the Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Germany.

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Źródło:

Clinical hemorheology and microcirculation [Clin Hemorheol Microcirc] 2021; Vol. 79 (1), pp. 231-243.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents*
Hepatoblastoma*/drug therapy
Liver Neoplasms*
Biotransformation ; Cell Line ; Clone Cells ; Cytochrome P-450 CYP3A/genetics ; Hep G2 Cells ; Humans ; Onium Compounds

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 38.

Tytuł:

Cytostatic compounds in sludge and sediment: extraction and determination by a combination of microwave-assisted extraction and UHPLC-MS/MS.

Autorzy:

Santana-Viera S; Instituto Universitario de Estudios Ambientales y Recursos Naturales (i-UNAT), Universidad de Las Palmas de Gran Canaria, 35017, Las Palmas de Gran Canaria, Spain.
Tuček J; Faculty of Natural Sciences, Department of Analytical Chemistry, Comenius University in Bratislava, Ilkovičova 6, 842 15, Bratislava, Slovak Republic.
Torres-Padrón ME; Instituto Universitario de Estudios Ambientales y Recursos Naturales (i-UNAT), Universidad de Las Palmas de Gran Canaria, 35017, Las Palmas de Gran Canaria, Spain.
Sosa-Ferrera Z; Instituto Universitario de Estudios Ambientales y Recursos Naturales (i-UNAT), Universidad de Las Palmas de Gran Canaria, 35017, Las Palmas de Gran Canaria, Spain.
Santana-Rodríguez JJ; Instituto Universitario de Estudios Ambientales y Recursos Naturales (i-UNAT), Universidad de Las Palmas de Gran Canaria, 35017, Las Palmas de Gran Canaria, Spain. .
Halko R; Faculty of Natural Sciences, Department of Analytical Chemistry, Comenius University in Bratislava, Ilkovičova 6, 842 15, Bratislava, Slovak Republic.

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Źródło:

Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2020 Jun; Vol. 412 (15), pp. 3639-3651. Date of Electronic Publication: 2020 Apr 14.

Typ publikacji:

Journal Article; Validation Study

MeSH Terms:

Chromatography, High Pressure Liquid/*methods
Cytostatic Agents/*analysis
Geologic Sediments/*analysis
Sewage/*analysis
Tandem Mass Spectrometry/*methods
Water Pollutants, Chemical/*analysis
Cytostatic Agents/isolation & purification ; Limit of Detection ; Microwaves ; Solid Phase Extraction/methods ; Water Pollutants, Chemical/isolation & purification

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 39.

Tytuł:

Green Synthesis of MnO Nanoparticles Using Abutilon indicum Leaf Extract for Biological, Photocatalytic, and Adsorption Activities.

Autorzy:

Khan SA; Center of Super-Diamond and Advanced Films (COSDAF), Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China.
Shahid S; Department of Chemistry, University of Management and Technology, Lahore-54770, Pakistan.
Shahid B; Department of Chemistry, University of Management and Technology, Lahore-54770, Pakistan.
Fatima U; Department of Chemistry, University of Management and Technology, Lahore-54770, Pakistan.
Abbasi SA; Department of Mathematics, Statistics, and Physics, Qatar University, Doha 2713, Qatar.

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Źródło:

Biomolecules [Biomolecules] 2020 May 19; Vol. 10 (5). Date of Electronic Publication: 2020 May 19.

Typ publikacji:

Journal Article

MeSH Terms:

Anti-Bacterial Agents/*chemical synthesis
Cytostatic Agents/*chemical synthesis
Malvaceae/*chemistry
Manganese Compounds/*chemistry
Nanoparticles/*chemistry
Oxides/*chemistry
Plant Extracts/*chemistry
Adsorption ; Anti-Bacterial Agents/pharmacology ; Bacillus subtilis/drug effects ; Bordetella bronchiseptica/drug effects ; Cytostatic Agents/pharmacology ; Green Chemistry Technology ; HeLa Cells ; Humans ; Staphylococcus aureus/drug effects

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 40.

Tytuł:

Added value recyclability of glass fiber waste as photo-oxidation catalyst for toxic cytostatic micropollutants.

Autorzy:

Nechifor G; Faculty of Applied Chemistry and Material Science, Polytechnic University of Bucharest, 060042, Bucharest, Romania.
Totu EE; Faculty of Applied Chemistry and Material Science, Polytechnic University of Bucharest, 060042, Bucharest, Romania. .
Nechifor AC; Faculty of Applied Chemistry and Material Science, Polytechnic University of Bucharest, 060042, Bucharest, Romania.
Constantin L; National Research and Development Institute for Industrial Ecology - ECOIND Bucharest, 71-73 Drumul Podul Dambovitei Str., 060652, Bucharest, Romania.
Constantin AM; National Research and Development Institute for Industrial Ecology - ECOIND Bucharest, 71-73 Drumul Podul Dambovitei Str., 060652, Bucharest, Romania.
Cărăuşu ME; Department of Public Health and Management, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115, Iasi, Romania.
Isildak I; Department of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, 34210, Esenler-Istanbul, Turkey.

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Źródło:

Scientific reports [Sci Rep] 2020 Jan 10; Vol. 10 (1), pp. 136. Date of Electronic Publication: 2020 Jan 10.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Photochemical Processes*
Waste Products*
Cytostatic Agents/*chemistry
Environmental Pollutants/*chemistry
Glass/*chemistry
Recycling/*methods
Silicon Dioxide/*chemistry
Catalysis ; Cytostatic Agents/toxicity ; Environmental Pollutants/toxicity ; Microspheres ; Oxidation-Reduction ; Surface Properties ; Titanium/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 41.

Tytuł:

Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer.

Autorzy:

Yuan SJ; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China.; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 43007, China.
Xu YH; Department of Ophthalmology, Institute of Ophthalmological Research, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Wang C; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China.; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 43007, China.
An HC; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China.; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 43007, China.
Xu HZ; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China.; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 43007, China.
Li K; Center for Lab Teaching, School of Basic Medicine, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China.
Komatsu N; Graduate School of Human and Environmental Studies, Kyoto University, Sakyo-ku, Kyoto, 606-8501, Japan.
Zhao L; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection & School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, Jiangsu, China. .
Chen X; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China. .; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 43007, China. .

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Źródło:

Journal of nanobiotechnology [J Nanobiotechnology] 2019 Oct 17; Vol. 17 (1), pp. 110. Date of Electronic Publication: 2019 Oct 17.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents/*administration & dosage
Cytostatic Agents/*administration & dosage
Doxorubicin/*administration & dosage
Glycerol/*chemistry
Nanoconjugates/*chemistry
Polymers/*chemistry
Triple Negative Breast Neoplasms/*drug therapy
Animals ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Cytostatic Agents/therapeutic use ; Doxorubicin/therapeutic use ; Drug Resistance, Neoplasm/drug effects ; Female ; Humans ; Immune Tolerance/drug effects ; Mice, Inbred BALB C ; Nanodiamonds/chemistry ; Triple Negative Breast Neoplasms/immunology ; Tumor Microenvironment/drug effects

Czasopismo naukowe

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Skocz do pozycji: 42.

Tytuł:

Removal of anthracycline cytostatics from aquatic environment: Comparison of nanocrystalline titanium dioxide and decontamination agents.

Autorzy:

Šťastný M; Institute of Inorganic Chemistry of the Czech Academy of Sciences, Řež, Czech Republic.
Štengl V; Institute of Inorganic Chemistry of the Czech Academy of Sciences, Řež, Czech Republic.
Štenglová-Netíková I; 1st Faculty of Medicine, Charles University in Prague, Ovocný trh, Czech Republic.
Šrámová-Slušná M; Institute of Inorganic Chemistry of the Czech Academy of Sciences, Řež, Czech Republic.
Janoš P; Faculty of the Environment, J.E.Purkyně University in Ústí nad Labem, Ústí nad Labem, Czech Republic.

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Źródło:

PloS one [PLoS One] 2019 Oct 11; Vol. 14 (10), pp. e0223117. Date of Electronic Publication: 2019 Oct 11 (Print Publication: 2019).

Typ publikacji:

Comparative Study; Journal Article

MeSH Terms:

Cytostatic Agents/*chemistry
Doxorubicin/*analogs & derivatives
Nanostructures/*chemistry
Titanium/*chemistry
Water Pollutants, Chemical/*chemistry
Adsorption ; Crystallization ; Cytostatic Agents/isolation & purification ; Decontamination/methods ; Doxorubicin/chemistry ; Doxorubicin/isolation & purification ; Hydrolysis ; Particle Size ; Sodium Hydroxide/chemistry ; Sodium Hypochlorite/chemistry ; Surface Properties ; Water Pollutants, Chemical/isolation & purification

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Skocz do pozycji: 43.

Tytuł:

Biochemical profile and in vitro biological activities of extracts from seven folk medicinal plants growing wild in southern Tunisia.

Autorzy:

Tlili H; Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms, Institute of Arid Regions (IRA), Medenine, Tunisia.
Hanen N; Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms, Institute of Arid Regions (IRA), Medenine, Tunisia.
Ben Arfa A; Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms, Institute of Arid Regions (IRA), Medenine, Tunisia.
Neffati M; Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms, Institute of Arid Regions (IRA), Medenine, Tunisia.
Boubakri A; Laboratory of Pastoral Ecosystems and Valorisation of Spontaneous Plants and Microorganisms, Institute of Arid Regions (IRA), Medenine, Tunisia.
Buonocore D; Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Dossena M; Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Verri M; Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Doria E; Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.

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Źródło:

PloS one [PLoS One] 2019 Sep 17; Vol. 14 (9), pp. e0213049. Date of Electronic Publication: 2019 Sep 17 (Print Publication: 2019).

Typ publikacji:

Journal Article

MeSH Terms:

Anti-Inflammatory Agents/*chemistry
Cytostatic Agents/*chemistry
Magnoliopsida/*chemistry
Plant Extracts/*chemistry
Anti-Inflammatory Agents/pharmacology ; Caco-2 Cells ; Cell Proliferation/drug effects ; Cytostatic Agents/pharmacology ; Humans ; Plant Extracts/pharmacology ; Plants, Medicinal/chemistry ; Tunisia

Czasopismo naukowe

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Skocz do pozycji: 44.

Tytuł:

Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549.

Autorzy:

Bistrović A; a Department of Organic Chemistry, Faculty of Chemical Engineering and Technology , University of Zagreb , Zagreb , Croatia.
Grbčić P; b Department of Biotechnology, Center for High-Throughput Technologies , University of Rijeka , Rijeka , Croatia.
Harej A; b Department of Biotechnology, Center for High-Throughput Technologies , University of Rijeka , Rijeka , Croatia.
Sedić M; b Department of Biotechnology, Center for High-Throughput Technologies , University of Rijeka , Rijeka , Croatia.
Kraljević-Pavelić S; b Department of Biotechnology, Center for High-Throughput Technologies , University of Rijeka , Rijeka , Croatia.
Koštrun S; c Chemistry Department , Fidelta Ltd. , Zagreb , Croatia.
Plavec J; d Slovenian NMR Centre , National Institute of Chemistry , Ljubljana , Slovenia.; e En-FIST Centre of Excellence , Ljubljana , Slovenia.; f Faculty of Chemistry and Chemical Technology , University of Ljubljana , Ljubljana , Slovenia.
Makuc D; d Slovenian NMR Centre , National Institute of Chemistry , Ljubljana , Slovenia.; e En-FIST Centre of Excellence , Ljubljana , Slovenia.
Raić-Malić S; a Department of Organic Chemistry, Faculty of Chemical Engineering and Technology , University of Zagreb , Zagreb , Croatia.

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Źródło:

Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2018 Dec; Vol. 33 (1), pp. 271-285.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents/*pharmacology
Carcinoma, Non-Small-Cell Lung/*drug therapy
Cytostatic Agents/*pharmacology
Lung Neoplasms/*drug therapy
Purines/*pharmacology
Small Molecule Libraries/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Proliferation/drug effects ; Cells, Cultured ; Cytostatic Agents/chemical synthesis ; Cytostatic Agents/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Lung Neoplasms/pathology ; Models, Molecular ; Molecular Structure ; Purines/chemical synthesis ; Purines/chemistry ; Small Molecule Libraries/chemical synthesis ; Small Molecule Libraries/chemistry ; Structure-Activity Relationship ; Triazoles/chemistry ; Triazoles/pharmacology

Czasopismo naukowe

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Skocz do pozycji: 45.

Tytuł:

Binding of BRACO19 to a Telomeric G-Quadruplex DNA Probed by All-Atom Molecular Dynamics Simulations with Explicit Solvent.

Autorzy:

Machireddy B; College of Science and Mathematics, Rowan University, Glassboro, NJ 08028, USA. .
Sullivan HJ; College of Science and Mathematics, Rowan University, Glassboro, NJ 08028, USA. .
Wu C; College of Science and Mathematics, Rowan University, Glassboro, NJ 08028, USA. .

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2019 Mar 13; Vol. 24 (6). Date of Electronic Publication: 2019 Mar 13.

Typ publikacji:

Journal Article

MeSH Terms:

Acridines/*pharmacology
Cytostatic Agents/*pharmacology
DNA/*chemistry
DNA/*metabolism
Acridines/chemistry ; Binding Sites ; Cell Line, Tumor ; Cytostatic Agents/chemistry ; G-Quadruplexes ; Humans ; Models, Molecular ; Molecular Dynamics Simulation ; Nucleic Acid Conformation ; Solvents/chemistry

Czasopismo naukowe

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Skocz do pozycji: 46.

Tytuł:

Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate.

Autorzy:

Gaugaz FZ; ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, 8093 Zürich, Switzerland. .
Chicca A; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland. .
Redondo-Horcajo M; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. .
Barasoain I; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. .
Díaz JF; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. .
Altmann KH; ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, 8093 Zürich, Switzerland. .

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2019 Mar 05; Vol. 20 (5). Date of Electronic Publication: 2019 Mar 05.

Typ publikacji:

Journal Article

MeSH Terms:

Cytostatic Agents/*chemical synthesis
Epothilones/*pharmacology
Microtubules/*metabolism
Peptides/*pharmacology
Tubulin Modulators/*chemical synthesis
Animals ; Cattle ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cytostatic Agents/pharmacology ; Epothilones/chemistry ; ErbB Receptors/metabolism ; HEK293 Cells ; Humans ; Peptides/chemistry ; Tubulin/metabolism ; Tubulin Modulators/pharmacology

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Skocz do pozycji: 47.

Tytuł:

NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination.

Autorzy:

Ruscetti M; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Leibold J; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Bott MJ; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Fennell M; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Kulick A; Department of Molecular Pharmacology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Salgado NR; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Chen CC; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Ho YJ; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Sanchez-Rivera FJ; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Feucht J; Center for Cell Engineering and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Baslan T; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Tian S; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Chen HA; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Romesser PB; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Poirier JT; Department of Molecular Pharmacology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Rudin CM; Department of Molecular Pharmacology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
de Stanchina E; Department of Molecular Pharmacology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Manchado E; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Sherr CJ; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
Lowe SW; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. .; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

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Źródło:

Science (New York, N.Y.) [Science] 2018 Dec 21; Vol. 362 (6421), pp. 1416-1422.

Typ publikacji:

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

MeSH Terms:

Cytotoxicity, Immunologic*
Immunologic Surveillance*
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Cyclin-Dependent Kinase 4/*antagonists & inhibitors
Cyclin-Dependent Kinase 6/*antagonists & inhibitors
Cytostatic Agents/*therapeutic use
Killer Cells, Natural/*immunology
Lung Neoplasms/*drug therapy
Aminopyridines/pharmacology ; Aminopyridines/therapeutic use ; Animals ; Apoptosis ; Benzimidazoles/pharmacology ; Benzimidazoles/therapeutic use ; Cellular Senescence ; Cytostatic Agents/pharmacology ; Humans ; Intercellular Adhesion Molecule-1/metabolism ; Lung Neoplasms/pathology ; Mice ; Mice, Inbred C57BL ; Mitogen-Activated Protein Kinases ; Molecular Targeted Therapy ; Mutation ; Piperazines/pharmacology ; Piperazines/therapeutic use ; Proto-Oncogene Proteins p21(ras)/genetics ; Purines/pharmacology ; Purines/therapeutic use ; Pyridines/pharmacology ; Pyridines/therapeutic use ; Pyridones/pharmacology ; Pyridones/therapeutic use ; Pyrimidinones/pharmacology ; Pyrimidinones/therapeutic use ; Retinoblastoma Protein/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Xenograft Model Antitumor Assays

Czasopismo naukowe

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Skocz do pozycji: 48.

Tytuł:

Isoxazolidine Conjugates of N3-Substituted 6-Bromoquinazolinones-Synthesis, Anti-Varizella-Zoster Virus, and Anti-Cytomegalovirus Activity.

Autorzy:

Grabkowska-Drużyc M; Bioorganic Chemistry Laboratory, Faculty of Pharmacy, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland. .
Andrei G; Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium. .
Schols D; Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium. .
Snoeck R; Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium. .
Piotrowska DG; Bioorganic Chemistry Laboratory, Faculty of Pharmacy, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland. .

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2018 Jul 28; Vol. 23 (8). Date of Electronic Publication: 2018 Jul 28.

Typ publikacji:

Journal Article

MeSH Terms:

Antiviral Agents/*chemical synthesis
Cytomegalovirus/*drug effects
Cytostatic Agents/*chemical synthesis
Herpesvirus 3, Human/*drug effects
Isoxazoles/*chemical synthesis
Quinazolinones/*chemical synthesis
Animals ; Antiviral Agents/pharmacology ; Cell Line ; Chlorocebus aethiops ; Cycloaddition Reaction ; Cytomegalovirus/growth & development ; Cytostatic Agents/pharmacology ; Dogs ; Drug Design ; Fibroblasts/drug effects ; Fibroblasts/virology ; HeLa Cells ; Herpesvirus 3, Human/growth & development ; Humans ; Inhibitory Concentration 50 ; Isoxazoles/pharmacology ; Madin Darby Canine Kidney Cells ; Nitrogen Oxides/chemistry ; Quinazolinones/pharmacology ; Structure-Activity Relationship ; Vero Cells ; Virus Replication/drug effects

Czasopismo naukowe

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Skocz do pozycji: 49.

Tytuł:

Synthesis and in vitro evaluation of antiviral and cytostatic properties of novel 8-triazolyl acyclovir derivatives.

Autorzy:

Saftić D; a Division of Organic Chemistry and Biochemistry , Ruđer Bošković Institute , Zagreb , Croatia.
Žinić B; a Division of Organic Chemistry and Biochemistry , Ruđer Bošković Institute , Zagreb , Croatia.
Glavaš-Obrovac L; b Department of Chemistry, Biochemistry and Clinical Chemistry, Faculty of Medicine , Osijek , Croatia.
Studzińska M; c Laboratory of Molecular Virology and Biological Chemistry , Institute of Medical Biology of the Polish Academy of Sciences , Łódź , Poland.
Paradowska E; c Laboratory of Molecular Virology and Biological Chemistry , Institute of Medical Biology of the Polish Academy of Sciences , Łódź , Poland.
Leśnikowski ZJ; c Laboratory of Molecular Virology and Biological Chemistry , Institute of Medical Biology of the Polish Academy of Sciences , Łódź , Poland.

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Źródło:

Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2018; Vol. 37 (7), pp. 397-414. Date of Electronic Publication: 2018 Nov 17.

Typ publikacji:

Journal Article

MeSH Terms:

Acyclovir/*chemistry
Antiviral Agents/*chemistry
Antiviral Agents/*pharmacology
Cytostatic Agents/*chemistry
Cytostatic Agents/*pharmacology
Alkynes/chemistry ; Animals ; Antiviral Agents/chemical synthesis ; Caco-2 Cells ; Cycloaddition Reaction ; Cytostatic Agents/chemical synthesis ; Dogs ; Drug Evaluation, Preclinical/methods ; Drug Screening Assays, Antitumor ; Guanosine/chemistry ; Humans ; Jurkat Cells ; K562 Cells ; Madin Darby Canine Kidney Cells ; Magnetic Resonance Spectroscopy ; Propanols/chemistry

Czasopismo naukowe

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Skocz do pozycji: 50.

Tytuł:

Triple Isozyme Lactic Acid Dehydrogenase Inhibition in Fully Viable MDA-MB-231 Cells Induces Cytostatic Effects That Are Not Reversed by Exogenous Lactic Acid.

Autorzy:

Mazzio E; Institute of Public Health, College of Pharmacy & Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA.
Mack N; Institute of Public Health, College of Pharmacy & Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA.; Institute of Computational Medicine, Johns Hopkins Whiting School of Engineering, Baltimore, MD 21218, USA.
Badisa RB; Institute of Public Health, College of Pharmacy & Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA.
Soliman KFA; Institute of Public Health, College of Pharmacy & Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA.

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Źródło:

Biomolecules [Biomolecules] 2021 Nov 24; Vol. 11 (12). Date of Electronic Publication: 2021 Nov 24.

Typ publikacji:

Journal Article; Research Support, N.I.H., Extramural

MeSH Terms:

Cytostatic Agents/*pharmacology
Lactic Acid/*metabolism
Pyridones/*pharmacology
Thiophenes/*pharmacology
Triple Negative Breast Neoplasms/*metabolism
Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Regulatory Networks/drug effects ; Glycolysis ; High-Throughput Screening Assays ; Humans ; Lactic Acid/pharmacology ; Triple Negative Breast Neoplasms/drug therapy ; Triple Negative Breast Neoplasms/genetics ; Tumor Microenvironment/drug effects

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