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Wyszukujesz frazę ""Cytotoxicity Tests, Immunologic"" wg kryterium: Temat


Tytuł:
A novel thermostable beetle luciferase based cytotoxicity assay.
Autorzy:
Choi S; Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Matta H; Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Gopalakrishnan R; Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Natarajan V; Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Gong S; Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Jeronimo A; Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Kuo WY; Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Bravo B; Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Chaudhary PM; Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 May 11; Vol. 11 (1), pp. 10002. Date of Electronic Publication: 2021 May 11.
Typ publikacji:
Evaluation Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Benzothiazoles*
Cytotoxicity Tests, Immunologic*
Luciferases*
Coleoptera/*enzymology
Animals ; Humans ; K562 Cells ; Mice, Inbred NOD ; Mice, SCID
Czasopismo naukowe
Tytuł:
Human Leukemia T-Cell Lines as Alternatives to Animal Use for Detecting Biologically Active Staphylococcal Enterotoxin Type B.
Autorzy:
Rasooly R; Foodborne Toxin Detection & Prevention Research Unit, Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA.
Do P; Foodborne Toxin Detection & Prevention Research Unit, Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA.
He X; Foodborne Toxin Detection & Prevention Research Unit, Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA.
Hernlem B; Foodborne Toxin Detection & Prevention Research Unit, Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA.
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Źródło:
Toxins [Toxins (Basel)] 2021 Apr 23; Vol. 13 (5). Date of Electronic Publication: 2021 Apr 23.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, T-Cell*
Animal Testing Alternatives/*methods
Cytotoxicity Tests, Immunologic/*methods
Enterotoxins/*pharmacology
Animals ; Cell Line, Tumor ; Enterotoxins/analysis ; Histocompatibility Antigens Class II/drug effects ; Humans ; Limit of Detection ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł:
Cytotoxicity of β-Cyclodextrins in Retinal Explants for Intravitreal Drug Formulations.
Autorzy:
Prajapati M; Faculty of Pharmaceutical Sciences, University of Iceland, Hofsvallagata 53, IS-107 Reykjavik, Iceland.
Christensen G; Institute for Ophthalmic Research, University of Tübingen, Elfriede-Aulhorn-Strasse 5-7, 72076 Tübingen, Germany.
Paquet-Durand F; Institute for Ophthalmic Research, University of Tübingen, Elfriede-Aulhorn-Strasse 5-7, 72076 Tübingen, Germany.
Loftsson T; Faculty of Pharmaceutical Sciences, University of Iceland, Hofsvallagata 53, IS-107 Reykjavik, Iceland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Mar 09; Vol. 26 (5). Date of Electronic Publication: 2021 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Cyclodextrins/*pharmacology
Cyclodextrins/*toxicity
Retina/*drug effects
2-Hydroxypropyl-beta-cyclodextrin/chemistry ; 2-Hydroxypropyl-beta-cyclodextrin/pharmacology ; 2-Hydroxypropyl-beta-cyclodextrin/toxicity ; Animals ; Cyclodextrins/metabolism ; Cytotoxicity Tests, Immunologic/methods ; Drug Compounding ; Drug Delivery Systems/methods ; Excipients ; Female ; Male ; Mice ; Mice, Inbred C3H ; Retina/metabolism ; Solubility ; beta-Cyclodextrins/chemistry ; beta-Cyclodextrins/pharmacology ; beta-Cyclodextrins/toxicity
Czasopismo naukowe
Tytuł:
MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities.
Autorzy:
Lafleur MA; Translational Safety & Bioanalytical Sciences, Amgen Research, Amgen Inc., Thousand Oaks, CA, USA.
Werner J; Translational Safety & Bioanalytical Sciences, Amgen Research, Amgen Inc., Thousand Oaks, CA, USA.
Fort M; Translational Safety & Bioanalytical Sciences, Amgen Research, Amgen Inc., Thousand Oaks, CA, USA.
Lobenhofer EK; Translational Safety & Bioanalytical Sciences, Amgen Research, Amgen Inc., Thousand Oaks, CA, USA.
Balazs M; Translational Safety & Bioanalytical Sciences, Amgen Research, Amgen, Inc., South San Francisco, CA, USA.
Goyos A; Translational Safety & Bioanalytical Sciences, Amgen Research, Amgen, Inc., South San Francisco, CA, USA.
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Źródło:
Journal of immunotoxicology [J Immunotoxicol] 2020 Dec; Vol. 17 (1), pp. 110-121.
Typ publikacji:
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Degranulation/*drug effects
High-Throughput Screening Assays/*methods
Mast Cells/*drug effects
Nerve Tissue Proteins/*metabolism
Peptides/*adverse effects
Receptors, G-Protein-Coupled/*metabolism
Receptors, Neuropeptide/*metabolism
Antigens, CD34/metabolism ; Cell Degranulation/immunology ; Cell Engineering ; Cells, Cultured ; Cytotoxicity Tests, Immunologic/methods ; Drug Evaluation, Preclinical/methods ; Hematopoietic Stem Cell Mobilization ; Hematopoietic Stem Cells/metabolism ; Histamine/analysis ; Histamine/metabolism ; Humans ; Mast Cells/immunology ; Mast Cells/metabolism ; Primary Cell Culture ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł:
In vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish.
Autorzy:
Phelps DW; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.; Comparative Medicine Institute, North Carolina State University, Raleigh, NC, USA.
Fletcher AA; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
Rodriguez-Nunez I; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
Balik-Meisner MR; Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.
Tokarz DA; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.; Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
Reif DM; Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.; Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.; Bioinformatics Research Center, North Carolina State University, Raleigh, NC, USA.
Germolec DR; National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Yoder JA; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.; Comparative Medicine Institute, North Carolina State University, Raleigh, NC, USA.; Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
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Źródło:
Journal of immunotoxicology [J Immunotoxicol] 2020 Dec; Vol. 17 (1), pp. 94-104.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Benzo(a)pyrene/*adverse effects
Cytotoxicity Tests, Immunologic/*methods
Immunity, Innate/*drug effects
Reactive Oxygen Species/*analysis
Respiratory Burst/*drug effects
Animals ; Animals, Genetically Modified ; Blood Cell Count ; Embryo, Nonmammalian ; Estradiol/adverse effects ; Feasibility Studies ; High-Throughput Screening Assays/methods ; Macrophages/drug effects ; Macrophages/immunology ; Methoxychlor/adverse effects ; Neutrophils/drug effects ; Neutrophils/immunology ; Organometallic Compounds/adverse effects ; Phenanthrenes/adverse effects ; Reactive Oxygen Species/metabolism ; Respiratory Burst/immunology ; Zebrafish
Czasopismo naukowe
Tytuł:
Cross-company evaluation of the human lymphocyte activation assay.
Autorzy:
Collinge M; Pfizer Inc, Groton, CT, USA.
Schneider P; Pfizer Inc, Groton, CT, USA.
Li D; Pfizer Inc, Groton, CT, USA.
Parish S; Health and Environmental Sciences Institute, Washington, DC, USA.
Dumont C; Charles River Laboratories, Senneville, Canada.
Freebern W; Bristol-Myers Squibb, New Brunswick, NJ, USA.
Ghanime J; Charles River Laboratories, Senneville, Canada.
Guimont-Derochers F; Charles River Laboratories, Senneville, Canada.
Langenkamp A; Roche Pharmaceutical Research and Development, Basel, Switzerland.
Lebron J; Merck, West Point, PA, USA.
Li N; Merck, West Point, PA, USA.
Marban C; Roche Pharmaceutical Research and Development, Basel, Switzerland.
Plitnick L; Merck, West Point, PA, USA.
Wheeler J; Bristol-Myers Squibb, New Brunswick, NJ, USA.
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Źródło:
Journal of immunotoxicology [J Immunotoxicol] 2020 Dec; Vol. 17 (1), pp. 51-58.
Typ publikacji:
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Assay/*instrumentation
Cytotoxicity Tests, Immunologic/*methods
Drug Evaluation, Preclinical/*methods
Lymphocyte Activation/*drug effects
Cells, Cultured ; Cyclosporine/pharmacology ; Healthy Volunteers ; Humans ; Immunosuppressive Agents/pharmacology ; Influenza Vaccines/immunology ; Inhibitory Concentration 50 ; Leukocytes, Mononuclear ; Lymphocyte Activation/immunology ; Mycophenolic Acid/pharmacology ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
Development of an antibody-dependent cellular cytotoxicity reporter assay for measuring anti-Middle East Respiratory Syndrome antibody bioactivity.
Autorzy:
Cao J; Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, No. 31, Huotuo Road, Biomedical Base, Daxing District, Beijing, 102629, China.; Department of Physiology and Pathopysiology, Capital Medical University, Youanmen, Fengtai District, Beijing, 100069, China.
Wang L; Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, No. 31, Huotuo Road, Biomedical Base, Daxing District, Beijing, 102629, China.
Yu C; Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, No. 31, Huotuo Road, Biomedical Base, Daxing District, Beijing, 102629, China.
Wang K; Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, No. 31, Huotuo Road, Biomedical Base, Daxing District, Beijing, 102629, China.
Wang W; Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, No. 31, Huotuo Road, Biomedical Base, Daxing District, Beijing, 102629, China.
Yan J; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Academy of Sciences, Beijing, 100101, China.
Li Y; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Academy of Sciences, Beijing, 100101, China.
Yang Y; Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, No. 31, Huotuo Road, Biomedical Base, Daxing District, Beijing, 102629, China.
Wang X; Department of Physiology and Pathopysiology, Capital Medical University, Youanmen, Fengtai District, Beijing, 100069, China. .
Wang J; Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, No. 31, Huotuo Road, Biomedical Base, Daxing District, Beijing, 102629, China. wangjz_.
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Źródło:
Scientific reports [Sci Rep] 2020 Oct 06; Vol. 10 (1), pp. 16615. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Viral/*analysis
Antibody-Dependent Cell Cytotoxicity/*immunology
Coronavirus Infections/*immunology
Cytotoxicity Tests, Immunologic/*methods
Middle East Respiratory Syndrome Coronavirus/*immunology
Middle East Respiratory Syndrome Coronavirus/*metabolism
Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Coronavirus Infections/virology ; Genes, Reporter ; HEK293 Cells ; Humans ; Jurkat Cells ; Luciferases/genetics ; Middle East Respiratory Syndrome Coronavirus/genetics ; NFATC Transcription Factors/genetics ; Receptors, IgG/genetics ; Receptors, IgG/immunology ; Response Elements ; Spike Glycoprotein, Coronavirus/metabolism ; Transfection
Czasopismo naukowe
Tytuł:
Carbamylation reduces the capacity of IgG for hexamerization and complement activation.
Autorzy:
Lubbers R; Department Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
Oostindie SC; Genmab, Utrecht, the Netherlands.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
Dijkstra DJ; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
Parren PWHI; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.; Lava Therapeutics, Utrecht, the Netherlands.
Verheul MK; Department Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
Abendstein L; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
Sharp TH; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
de Ru A; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.
Janssen GMC; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.
van Veelen PA; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.
van den Bremer ETJ; Genmab, Utrecht, the Netherlands.
Bleijlevens B; Genmab, Utrecht, the Netherlands.
de Kreuk BJ; Genmab, Utrecht, the Netherlands.
Beurskens FJ; Genmab, Utrecht, the Netherlands.
Trouw LA; Department Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2020 Apr; Vol. 200 (1), pp. 1-11. Date of Electronic Publication: 2020 Jan 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arthritis, Rheumatoid/*immunology
Complement Activation/*immunology
Complement C1q/*immunology
Immunoglobulin G/*immunology
Aged ; Amino Acid Sequence ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/metabolism ; Arthritis, Rheumatoid/metabolism ; Cell Line, Tumor ; Complement C1q/metabolism ; Cytotoxicity Tests, Immunologic ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunoglobulin G/chemistry ; Immunoglobulin G/metabolism ; Male ; Mass Spectrometry ; Middle Aged ; Protein Carbamylation/immunology ; Protein Multimerization/immunology ; Synovial Fluid/immunology ; Synovial Fluid/metabolism ; Synovial Membrane/immunology ; Synovial Membrane/metabolism
Czasopismo naukowe
Tytuł:
Natural Killer Cell Function Tests by Flowcytometry-Based Cytotoxicity and IFN-γ Production for the Diagnosis of Adult Hemophagocytic Lymphohistiocytosis.
Autorzy:
Lee H; Department of Laboratory Medicine, Catholic Kwandong University International St. Mary's Hospital, Incheon 22711, Korea. .
Kim HS; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea. .
Lee JM; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea. .
Park KH; Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea. .
Choi AR; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea. .
Yoon JH; Department of Hematology, Catholic Hematology Hospital and Leukemia Research Institute, Seoul St. Mary's Hematology Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea. .
Ryu H; Samkwang Medical Laboratories, Seoul 06742, Korea. .
Oh EJ; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Oct 30; Vol. 20 (21). Date of Electronic Publication: 2019 Oct 30.
Typ publikacji:
Journal Article
MeSH Terms:
Interferon-gamma/*metabolism
Killer Cells, Natural/*metabolism
Lymphohistiocytosis, Hemophagocytic/*diagnosis
Adult ; Aged ; Cytotoxicity Tests, Immunologic ; Early Diagnosis ; Female ; Ferritins/metabolism ; Flow Cytometry ; Humans ; Interferon-gamma/blood ; Killer Cells, Natural/immunology ; Lymphohistiocytosis, Hemophagocytic/immunology ; Male ; Middle Aged ; Retrospective Studies ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł:
Persistent gamma delta T-cell dysfunction in chronic HCV infection despite direct-acting antiviral therapy induced cure.
Autorzy:
Ghosh A; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland.
Mondal RK; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland.
Romani S; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland.
Bagchi S; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland.
Cairo C; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland.
Pauza CD; American Gene Technologies, Rockville, Maryland.
Kottilil S; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland.
Poonia B; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland.
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Źródło:
Journal of viral hepatitis [J Viral Hepat] 2019 Sep; Vol. 26 (9), pp. 1105-1116. Date of Electronic Publication: 2019 May 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Sustained Virologic Response*
Antiviral Agents/*therapeutic use
Hepatitis C, Chronic/*drug therapy
Hepatitis C, Chronic/*immunology
T-Lymphocytes/*pathology
Adult ; Aged ; Cell Proliferation/drug effects ; Clinical Trials as Topic ; Cohort Studies ; Cytokines/immunology ; Cytotoxicity Tests, Immunologic ; Female ; Hep G2 Cells ; Humans ; Lymphocyte Activation ; Male ; Middle Aged ; Phenotype ; Receptors, Antigen, T-Cell, gamma-delta ; T-Lymphocytes/immunology ; Zoledronic Acid/pharmacology
Czasopismo naukowe
Tytuł:
Image cytometry as an alternative to flow cytometry for the transplant histocompatibility crossmatch assay.
Autorzy:
Ramon DS; Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, Arizona.; Department of Pathology, University of Michigan School of Medicine, Ann Arbor, Michigan.
Franks T; Department of Pathology, University of Michigan School of Medicine, Ann Arbor, Michigan.
Jaramillo A; Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, Arizona.
Paradis BD; Department of Technology R&D, Nexcelom Bioscience LLC, Lawrence, Massachusetts.
Chan LL; Department of Technology R&D, Nexcelom Bioscience LLC, Lawrence, Massachusetts.
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Źródło:
HLA [HLA] 2019 Jun; Vol. 93 (6), pp. 436-444. Date of Electronic Publication: 2019 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
Flow Cytometry/*methods
Histocompatibility Testing/*methods
Image Cytometry/*methods
Alleles ; Color ; Cytotoxicity Tests, Immunologic/methods ; HLA Antigens/immunology ; Humans ; Immunoglobulin G/chemistry ; Linear Models ; Lymphocytes/cytology ; Phenotype ; Predictive Value of Tests ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł:
Antibody depletion for the treatment of crossmatch-positive pediatric heart transplant recipients.
Autorzy:
Daly KP; Department of Cardiology, Boston Children's Hospital, Boston, MA, USA.
Chandler SF
Almond CS
Singh TP
Mah H
Milford E
Matte GS
Bastardi HJ
Mayer JE
Fynn-Thompson F
Blume ED
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Źródło:
Pediatric transplantation [Pediatr Transplant] 2013 Nov; Vol. 17 (7), pp. 661-9. Date of Electronic Publication: 2013 Aug 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytotoxicity Tests, Immunologic*
Antibodies/*immunology
Graft Rejection/*immunology
Heart Transplantation/*methods
Adolescent ; Child ; Child, Preschool ; Female ; Graft Survival ; HLA Antigens/immunology ; Heart Failure/immunology ; Heart Failure/surgery ; Humans ; Immunoglobulins, Intravenous/administration & dosage ; Immunosuppressive Agents/therapeutic use ; Infant ; Male ; Retrospective Studies ; Risk Factors ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Evaluation of a new flow cytometry crossmatch procedure for simultaneous detection of cytotoxicity and antibody binding.
Autorzy:
Alheim M; Department of Laboratory Medicine, Division of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden. />Paul PK
Hauzenberger DM
Wikström AC
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Źródło:
Tissue antigens [Tissue Antigens] 2013 Aug; Vol. 82 (2), pp. 125-30. Date of Electronic Publication: 2013 Jun 17.
Typ publikacji:
Journal Article
MeSH Terms:
Cytotoxicity, Immunologic*
Cytotoxicity Tests, Immunologic/*methods
Flow Cytometry/*methods
B-Lymphocytes/cytology ; B-Lymphocytes/immunology ; Cytotoxicity Tests, Immunologic/standards ; Flow Cytometry/standards ; Humans ; Immunoglobulin G/metabolism ; Male ; Observer Variation ; Protein Binding ; Reproducibility of Results ; Sensitivity and Specificity ; T-Lymphocytes/cytology ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł:
After TGN1412: recent developments in cytokine release assays.
Autorzy:
Stebbings R; Biotherapeutics Group, NIBSC, Potters Bar, Hertfordshire EN6 3QG, UK. />Eastwood D
Poole S
Thorpe R
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Źródło:
Journal of immunotoxicology [J Immunotoxicol] 2013 Jan-Mar; Vol. 10 (1), pp. 75-82. Date of Electronic Publication: 2012 Sep 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytotoxicity Tests, Immunologic*
Antibodies, Monoclonal, Humanized/*adverse effects
CD4-Positive T-Lymphocytes/*drug effects
Interleukin-2/*immunology
Animals ; Antibodies, Immobilized ; CD28 Antigens/immunology ; CD4-Positive T-Lymphocytes/immunology ; Clinical Trials, Phase I as Topic ; Coculture Techniques ; Cytokines/immunology ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Endothelial Cells ; Humans ; Immunologic Memory/drug effects ; Inflammation/etiology ; Macaca fascicularis ; Predictive Value of Tests ; Treatment Failure
Czasopismo naukowe
Tytuł:
IL-26 in allergic contact dermatitis: Resource in a state of readiness.
Autorzy:
Caiazzo G; Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.
Di Caprio R; Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.
Lembo S; Department of Medicine, Surgery and Dentistry, 'Scuola Medica Salernitana' University of Salerno, Salerno, Italy.
Raimondo A; Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.
Scala E; Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.
Patruno C; Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.
Balato A; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
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Źródło:
Experimental dermatology [Exp Dermatol] 2018 Jun; Vol. 27 (6), pp. 681-684. Date of Electronic Publication: 2018 Apr 10.
Typ publikacji:
Journal Article
MeSH Terms:
Dermatitis, Allergic Contact/*immunology
Interleukins/*blood
Interleukins/*immunology
Leukocytes, Mononuclear/*metabolism
Bacterial Toxins/pharmacology ; Cell Line ; Cell Survival ; Cytotoxicity Tests, Immunologic ; Dermatitis, Allergic Contact/blood ; Dermatitis, Allergic Contact/genetics ; Dermatitis, Atopic/genetics ; Enterotoxins/pharmacology ; Gene Expression ; Gene Silencing ; Humans ; Interleukins/genetics ; Keratinocytes ; Nickel/pharmacology ; Psoriasis/genetics ; Superantigens/pharmacology ; Transfection
Czasopismo naukowe
Tytuł:
Review article: Luminex technology for HLA antibody detection in organ transplantation.
Autorzy:
Tait BD; Victorian Transplantation and Immunogenetic Service, Australian Red Cross Blood Service, Parkville, Victoria, Australia. />Hudson F
Cantwell L
Brewin G
Holdsworth R
Bennett G
Jose M
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Źródło:
Nephrology (Carlton, Vic.) [Nephrology (Carlton)] 2009 Apr; Vol. 14 (2), pp. 247-54.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Organ Transplantation*
Cytotoxicity Tests, Immunologic/*methods
HLA Antigens/*immunology
Isoantibodies/*blood
Algorithms ; Alleles ; Cost-Benefit Analysis ; Cytotoxicity Tests, Immunologic/economics ; Histocompatibility Testing ; Humans ; Microspheres ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł:
The CD107 mobilization assay: viable isolation and immunotherapeutic potential of tumor-cytolytic NK cells.
Autorzy:
Uhrberg M; Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
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Źródło:
Leukemia [Leukemia] 2005 May; Vol. 19 (5), pp. 707-9.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
Cytotoxicity Tests, Immunologic*
Antigens, CD/*immunology
Killer Cells, Natural/*immunology
Humans ; Killer Cells, Natural/metabolism ; Lysosomal Membrane Proteins ; Models, Biological
Czasopismo naukowe
Tytuł:
Flow cytometry beads rather than the antihuman globulin method should be used to detect HLA Class I IgG antibody (PRA) in cadaveric renal regraft candidates.
Autorzy:
Bryan CF; Midwest Transplant Network, Westwood, KS 66205, USA.
McDonald SB
Baier KA
Luger AM
Aeder MI
Murillo D
Muruve NA
Nelson PW
Shield CF 3rd
Warady BA
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Źródło:
Clinical transplantation [Clin Transplant] 2002; Vol. 16 Suppl 7, pp. 15-23.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Coombs Test*
Cytotoxicity Tests, Immunologic*
Flow Cytometry*/methods
Histocompatibility Antigens Class I/*immunology
Kidney Transplantation/*immunology
Humans ; Immunoglobulin G/immunology ; Reoperation
Czasopismo naukowe
Tytuł:
Cell mediated cytotoxicity assessment by relative changes in viable target absolute counts.
Autorzy:
Topakas GN; Department of Immunology, G. Gennimatas General Hospital of Athens, Greece. />Karchilaki IN
Cacoullos NT
Stavropoulos-Giokas C
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Źródło:
Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2001 Aug; Vol. 23 (3), pp. 459-75.
Typ publikacji:
Journal Article
MeSH Terms:
Cytotoxicity Tests, Immunologic/*methods
Cell Count ; Cell Survival ; Cells, Cultured ; Cytotoxicity Tests, Immunologic/statistics & numerical data ; Cytotoxicity, Immunologic ; Fluoresceins ; Fluorescent Dyes ; Humans ; In Vitro Techniques ; Killer Cells, Natural/immunology ; Lymphocyte Culture Test, Mixed ; Sensitivity and Specificity ; T-Lymphocytes, Cytotoxic/immunology
Czasopismo naukowe
Tytuł:
Enhanced natural killer cell activity is found in exposed uninfected recipients of hepatitis C-contaminated blood.
Autorzy:
Ow MM; Department of Medicine, University of Auckland, Auckland, New Zealand.; Hepatology Research Group, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK.
Hegazy D; Hepatology Research Group, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK.
Warshow UM; Hepatology Research Group, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK.
Cramp ME; Hepatology Research Group, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK.; Southwest Liver Unit, Derriford Hospital, Plymouth Hospitals NHS Trust, Plymouth, UK.
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Źródło:
Journal of viral hepatitis [J Viral Hepat] 2018 Mar; Vol. 25 (3), pp. 245-253. Date of Electronic Publication: 2017 Nov 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Environmental Exposure*
Hepatitis C/*immunology
Killer Cells, Natural/*immunology
Adult ; Aged ; Blood Transfusion ; CD56 Antigen/analysis ; Cohort Studies ; Cytotoxicity Tests, Immunologic ; England ; Female ; Humans ; Killer Cells, Natural/chemistry ; Lectins, C-Type/analysis ; Male ; Middle Aged ; Natural Cytotoxicity Triggering Receptor 3/analysis ; Receptors, KIR2DL3/analysis ; Receptors, Natural Killer Cell/analysis ; T-Lymphocytes/immunology
Czasopismo naukowe

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