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Tytuł :
Efficacy of dexamethasone treatment for patients with the acute respiratory distress syndrome caused by COVID-19: study protocol for a randomized controlled superiority trial.
Autorzy :
Villar J; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain. .; Multidisciplinary Organ Dysfunction Evaluation Research Network, Research Unit, Hospital Universitario Dr. Negrin, Barranco de la Ballena s/n, 4th floor - south wing, 35019, Las Palmas de Gran Canaria, Spain. .; Keenan Research Center for Biomedical Science at the Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada. .
Añón JM; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Intensive Care Unit, Hospital Universitario La Paz, IdIPaz, Madrid, Spain.
Ferrando C; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Department of Anesthesia and Critical Care, Hospital Clinic, Barcelona, Spain.
Aguilar G; Department of Anesthesia, Hospital Clínico Universitario, Valencia, Spain.
Muñoz T; Intensive Care Unit, Hospital Universitario de Cruces, Barakaldo, Vizcaya, Spain.
Ferreres J; Intensive Care Unit, Hospital Clínico Universitario, Valencia, Spain.
Ambrós A; Intensive Care Unit, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain.
Aldecoa C; Department of Anesthesia, Hospital Universitario Río Hortega, Valladolid, Spain.
Suárez-Sipmann F; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Intensive Care Unit, Hospital Universitario La Princesa, Madrid, Spain.
Thorpe KE; Applied Health Research Center, Li Ka Shing Knowledge Institute, Toronto, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.
Jüni P; Applied Health Research Center, Li Ka Shing Knowledge Institute, Toronto, Canada.; Department of Medicine and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.
Slutsky AS; Keenan Research Center for Biomedical Science at the Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada.; Department of Medicine, University of Toronto, Toronto, Canada.
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Corporate Authors :
DEXA-COVID19 Network
Źródło :
Trials [Trials] 2020 Aug 16; Vol. 21 (1), pp. 717. Date of Electronic Publication: 2020 Aug 16.
Typ publikacji :
Clinical Trial Protocol; Journal Article; Multicenter Study
Journal Info :
Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
MeSH Terms :
Betacoronavirus*
Randomized Controlled Trials as Topic*
Coronavirus Infections/*drug therapy
Dexamethasone/*therapeutic use
Pneumonia, Viral/*drug therapy
Adult ; Dexamethasone/adverse effects ; Humans ; Outcome Assessment, Health Care ; Pandemics ; Respiratory Distress Syndrome, Adult/drug therapy ; Sample Size
SCR Disease Name :
COVID-19
SCR Protocol :
COVID-19 drug treatment
SCR Organism :
severe acute respiratory syndrome coronavirus 2
Czasopismo naukowe
Tytuł :
Dexamethasone inhibits pancreatic tumor growth in preclinical models: Involvement of activating glucocorticoid receptor.
Autorzy :
Yao Y; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Yao QY; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Xue JS; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Tian XY; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, Beijing 100142, China.
An QM; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Cui LX; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Xu C; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Su H; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Yang L; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Feng YY; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Hao CY; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, Beijing 100142, China. Electronic address: .
Zhou TY; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Aug 15; Vol. 401, pp. 115118. Date of Electronic Publication: 2020 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0333 (Electronic) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol. Appl. Pharmacol. Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents, Hormonal/*therapeutic use
Dexamethasone/*therapeutic use
Pancreatic Neoplasms/*metabolism
Receptors, Glucocorticoid/*metabolism
Tumor Burden/*drug effects
Xenograft Model Antitumor Assays/*methods
A549 Cells ; Animals ; Antineoplastic Agents, Hormonal/pharmacology ; Dexamethasone/pharmacology ; Dose-Response Relationship, Drug ; Female ; Glucocorticoids/pharmacology ; Glucocorticoids/therapeutic use ; Humans ; MCF-7 Cells ; Mice, Inbred BALB C ; Mice, Nude ; Pancreatic Neoplasms/drug therapy ; Tumor Burden/physiology
Czasopismo naukowe
Tytuł :
In utero exposure to dexamethasone programs the development of the pancreatic β- and α-cells during early postnatal life.
Autorzy :
Santos-Silva JC; Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, 105 Alexander Flemming St., Campinas 13083-881, SP, Brazil.
da Silva PMR; Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, 105 Alexander Flemming St., Campinas 13083-881, SP, Brazil.
de Souza DN; Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, 105 Alexander Flemming St., Campinas 13083-881, SP, Brazil.
Teixeira CJ; Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, 105 Alexander Flemming St., Campinas 13083-881, SP, Brazil.
Bordin S; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, 1524 Prof. Lineu Prestes Ave., ICB 1, Sao Paulo 05508-000, SP, Brazil.
Anhê GF; Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, 105 Alexander Flemming St., Campinas 13083-881, SP, Brazil. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Aug 15; Vol. 255, pp. 117810. Date of Electronic Publication: 2020 May 28.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci. Subsets: MEDLINE
MeSH Terms :
Dexamethasone/*toxicity
Glucagon-Secreting Cells/*drug effects
Glucocorticoids/*toxicity
Insulin-Secreting Cells/*drug effects
Animals ; Dexamethasone/administration & dosage ; Female ; Gene Expression Regulation ; Glucagon/blood ; Glucagon-Secreting Cells/cytology ; Glucocorticoids/administration & dosage ; Insulin/blood ; Insulin Secretion/physiology ; Insulin-Secreting Cells/cytology ; Male ; Pregnancy ; Prenatal Exposure Delayed Effects/physiopathology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
What is the optimal regimen for intravenous dexamethasone administration in primary total hip arthroplasty?: A protocol of randomized controlled trial.
Autorzy :
Liang D; Department of Orthopedics, The First Medical Center in PLA General Hospital, Beijing, 100853, China.
Xue C
Liu W
Wang Y
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Sep 04; Vol. 99 (36), pp. e22070.
Typ publikacji :
Journal Article; Randomized Controlled Trial
Journal Info :
Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Anti-Inflammatory Agents/*administration & dosage
Arthroplasty, Replacement, Hip/*adverse effects
Dexamethasone/*administration & dosage
Pain, Postoperative/*drug therapy
Administration, Intravenous ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Inflammatory Agents/therapeutic use ; Case-Control Studies ; Dexamethasone/therapeutic use ; Humans ; Inflammation Mediators/metabolism ; Length of Stay ; Middle Aged ; Morphine/adverse effects ; Narcotics/adverse effects ; Opioid-Related Disorders/epidemiology ; Range of Motion, Articular ; Visual Analog Scale ; Young Adult
Czasopismo naukowe
Tytuł :
The efficacy and safety of multiple versus single doses dexamethasone in unicompartmental knee arthroplasty: A protocol of randomized controlled trial.
Autorzy :
Gao D; Department of Anesthesia, Hanchuan People's Hospital.
Liu X; Department of Anesthesia, Hanchuan People's Hospital.
Zhang F; Department of Anesthesia, Renmin Hospital of Wuhan University/Hubei General Hospital, Hubei, China.
Ding M; Department of Anesthesia, Hanchuan People's Hospital.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Aug 21; Vol. 99 (34), pp. e21671.
Typ publikacji :
Clinical Trial Protocol; Comparative Study; Journal Article
Journal Info :
Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Arthroplasty, Replacement, Knee*/methods
Dexamethasone/*administration & dosage
Glucocorticoids/*administration & dosage
Pain, Postoperative/*drug therapy
Postoperative Nausea and Vomiting/*diet therapy
Randomized Controlled Trials as Topic/*methods
Dexamethasone/adverse effects ; Glucocorticoids/adverse effects ; Humans ; Prospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Sinusitis caused by a rare organism, Cedecea lapagei .
Autorzy :
Duperret ME; Independent Researcher, Tucson, Arizona, USA .
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Źródło :
BMJ case reports [BMJ Case Rep] 2020 Jul 20; Vol. 13 (7). Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :
Case Reports; Journal Article
Journal Info :
Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE
MeSH Terms :
Dexamethasone/*administration & dosage
Enterobacteriaceae Infections/*drug therapy
Gentamicins/*administration & dosage
Sinusitis/*drug therapy
Acute Disease ; Amoxicillin-Potassium Clavulanate Combination/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Betacoronavirus ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Dexamethasone/therapeutic use ; Drug Therapy, Combination/methods ; Enterobacteriaceae/isolation & purification ; Enterobacteriaceae Infections/complications ; Gentamicins/therapeutic use ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Sinusitis/microbiology ; Treatment Outcome ; Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use
SCR Disease Name :
COVID-19
SCR Organism :
Cedecea lapagei; severe acute respiratory syndrome coronavirus 2
Czasopismo naukowe
Tytuł :
Corticosteroid Guidance for Pregnancy during COVID-19 Pandemic.
Autorzy :
McIntosh JJ; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, Wisconsin.
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Źródło :
American journal of perinatology [Am J Perinatol] 2020 Jun; Vol. 37 (8), pp. 809-812. Date of Electronic Publication: 2020 Apr 09.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Thieme-Stratton Country of Publication: United States NLM ID: 8405212 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-8785 (Electronic) Linking ISSN: 07351631 NLM ISO Abbreviation: Am J Perinatol Subsets: MEDLINE
MeSH Terms :
Betamethasone*/administration & dosage
Betamethasone*/adverse effects
Coronavirus Infections*/diagnosis
Coronavirus Infections*/therapy
Dexamethasone*/administration & dosage
Dexamethasone*/adverse effects
Pandemics*
Pneumonia, Viral*/diagnosis
Pneumonia, Viral*/therapy
Pregnancy Complications, Infectious*/therapy
Pregnancy Complications, Infectious*/virology
Fetal Organ Maturity/*drug effects
Premature Birth/*prevention & control
Prenatal Care/*methods
Betacoronavirus/isolation & purification ; Female ; Gestational Age ; Glucocorticoids/administration & dosage ; Glucocorticoids/adverse effects ; Humans ; Pregnancy ; Risk Assessment
SCR Disease Name :
COVID-19
SCR Organism :
severe acute respiratory syndrome coronavirus 2
Czasopismo naukowe
Tytuł :
Coronavirus breakthrough: dexamethasone is first drug shown to save lives.
Autorzy :
Ledford H
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Źródło :
Nature [Nature] 2020 Jun; Vol. 582 (7813), pp. 469.
Typ publikacji :
Wiadomości
Journal Info :
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
MeSH Terms :
Coronavirus Infections/*drug therapy
Dexamethasone/*therapeutic use
Pneumonia, Viral/*drug therapy
Adenosine Monophosphate/analogs & derivatives ; Adenosine Monophosphate/supply & distribution ; Adenosine Monophosphate/therapeutic use ; Alanine/analogs & derivatives ; Alanine/supply & distribution ; Alanine/therapeutic use ; Coronavirus Infections/epidemiology ; Coronavirus Infections/mortality ; Critical Illness ; Dexamethasone/administration & dosage ; Dexamethasone/adverse effects ; Dexamethasone/supply & distribution ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/mortality ; Preprints as Topic ; Randomized Controlled Trials as Topic ; Respiration, Artificial ; Risk Assessment ; Survival Rate
SCR Disease Name :
COVID-19
SCR Protocol :
COVID-19 drug treatment
Periodyk
Tytuł :
miR-148a/LDLR mediates hypercholesterolemia induced by prenatal dexamethasone exposure in male offspring rats.
Autorzy :
Li L; Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan 430071, China; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Wuhan 430071, China.
Hu W; Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan 430071, China; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Wuhan 430071, China.
Liu K; Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan 430071, China; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Wuhan 430071, China.
Zhang D; Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan 430071, China; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Wuhan 430071, China.
Liu M; Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan 430071, China; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Wuhan 430071, China.
Li X; Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan 430071, China; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Wuhan 430071, China.
Wang H; Department of Pharmacology, Wuhan University School of Basic Medical Sciences, Wuhan 430071, China; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Wuhan 430071, China. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 May 15; Vol. 395, pp. 114979. Date of Electronic Publication: 2020 Mar 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0333 (Electronic) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol. Appl. Pharmacol. Subsets: MEDLINE
MeSH Terms :
Prenatal Exposure Delayed Effects*
Dexamethasone/*adverse effects
Hypercholesterolemia/*etiology
Hypercholesterolemia/*metabolism
Receptors, LDL/*physiology
Animals ; Dexamethasone/administration & dosage ; Epigenesis, Genetic/drug effects ; Female ; Gene Expression/drug effects ; Gestational Age ; Liver/chemistry ; Liver/embryology ; Liver/metabolism ; Male ; Pregnancy ; Rats ; Rats, Wistar ; Receptors, Glucocorticoid/drug effects ; Receptors, Glucocorticoid/physiology ; Receptors, LDL/genetics
Czasopismo naukowe
Tytuł :
Melflufen plus dexamethasone in relapsed and refractory multiple myeloma (O-12-M1): a multicentre, international, open-label, phase 1-2 study.
Autorzy :
Richardson PG; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. Electronic address: .
Bringhen S; Division of Haematology, University of Torino, Azienda Ospedaliero-Universitaria, Città della Salute e della Scienza di Torino, Torino, Italy.
Voorhees P; Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
Plesner T; Department of Haematology, Vejle Hospital, Vejle, Denmark.
Mellqvist UH; Department of Haematology, Borås Hospital, Borås, Sweden.
Reeves B; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Paba-Prada C; Miami Cancer Institute at Baptist Health South Florida, Miami, FL, USA.
Zubair H; Oncopeptides AB, Stockholm, Sweden.
Byrne C; Oncopeptides AB, Stockholm, Sweden.
Chauhan D; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Anderson K; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Nordström E; Oncopeptides AB, Stockholm, Sweden.
Harmenberg J; Oncopeptides AB, Stockholm, Sweden.
Palumbo A; GlaxoSmithKline, Zug, Switzerland.
Sonneveld P; Department of Haematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
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Źródło :
The Lancet. Haematology [Lancet Haematol] 2020 May; Vol. 7 (5), pp. e395-e407. Date of Electronic Publication: 2020 Mar 23.
Typ publikacji :
Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study
Journal Info :
Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101643584 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3026 (Electronic) Linking ISSN: 23523026 NLM ISO Abbreviation: Lancet Haematol Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents, Alkylating/*therapeutic use
Antineoplastic Agents, Hormonal/*therapeutic use
Dexamethasone/*therapeutic use
Melphalan/*analogs & derivatives
Multiple Myeloma/*drug therapy
Phenylalanine/*analogs & derivatives
Aged ; Antineoplastic Agents, Alkylating/administration & dosage ; Antineoplastic Agents, Alkylating/adverse effects ; Antineoplastic Agents, Hormonal/administration & dosage ; Antineoplastic Agents, Hormonal/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Dexamethasone/administration & dosage ; Dexamethasone/adverse effects ; Disease-Free Survival ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Maximum Tolerated Dose ; Melphalan/administration & dosage ; Melphalan/adverse effects ; Melphalan/therapeutic use ; Middle Aged ; Neoplasm Recurrence, Local/drug therapy ; Phenylalanine/administration & dosage ; Phenylalanine/adverse effects ; Phenylalanine/therapeutic use
Czasopismo naukowe
Tytuł :
Effects of dexamethasone to reverse decreased hepatic midazolam metabolism in rats with acute renal failure.
Autorzy :
Doi M; Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Kajikawa N; Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Aiba T; Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2020 May; Vol. 50 (5), pp. 506-514. Date of Electronic Publication: 2019 Aug 28.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE
MeSH Terms :
Acute Kidney Injury/*metabolism
Anti-Inflammatory Agents/*pharmacology
Dexamethasone/*pharmacology
Midazolam/*metabolism
Animals ; Anti-Inflammatory Agents/metabolism ; Cytochrome P-450 CYP3A/metabolism ; Dexamethasone/metabolism ; Metabolic Clearance Rate ; Microsomes, Liver/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Implications for dosing regimen of enrofloxacin administered concurrently with dexamethasone in febrile buffalo calves.
Autorzy :
Sidhu PK; Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA. .
Ramalingam B; Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India.
Kaur G; Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India.
Rampal S; Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India.
Coetzee JF; Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA.
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Źródło :
Tropical animal health and production [Trop Anim Health Prod] 2020 May; Vol. 52 (3), pp. 1093-1102. Date of Electronic Publication: 2019 Nov 07.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Springer Country of Publication: United States NLM ID: 1277355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7438 (Electronic) Linking ISSN: 00494747 NLM ISO Abbreviation: Trop Anim Health Prod Subsets: MEDLINE
MeSH Terms :
Buffaloes*
Anti-Bacterial Agents/*pharmacology
Dexamethasone/*pharmacology
Enrofloxacin/*pharmacology
Fever/*veterinary
Animals ; Anti-Bacterial Agents/pharmacokinetics ; Dexamethasone/pharmacokinetics ; Dose-Response Relationship, Drug ; Drug Therapy, Combination/veterinary ; Enrofloxacin/pharmacokinetics ; Escherichia coli/chemistry ; Fever/drug therapy ; Fever/microbiology ; Injections, Intramuscular/veterinary ; Lipopolysaccharides/administration & dosage ; Male ; Random Allocation
Czasopismo naukowe
Tytuł :
Objective Verification of Acute Tinnitus and Validation of Efficacy of Systemic Steroids in Rats.
Autorzy :
Kim YC; Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea.; Department of Biomedical Sciences, BK21 Plus Research Center for Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.
Kim H; Department of Otorhinolaryngology Head and Neck Surgery, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.
Kim YS; Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea.
Jung SK; Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea.; Department of Biomedical Sciences, BK21 Plus Research Center for Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.
Park IY; Department of Biomedical Engineering, College of Medicine, Dankook University, Cheonan, Korea.
Choung YH; Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea.; Department of Biomedical Sciences, BK21 Plus Research Center for Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.
Jang JH; Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea. .
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Źródło :
Journal of Korean medical science [J Korean Med Sci] 2020 Apr 06; Vol. 35 (13), pp. e81. Date of Electronic Publication: 2020 Apr 06.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Korean Academy of Medical Science Country of Publication: Korea (South) NLM ID: 8703518 Publication Model: Electronic Cited Medium: Internet ISSN: 1598-6357 (Electronic) Linking ISSN: 10118934 NLM ISO Abbreviation: J. Korean Med. Sci. Subsets: MEDLINE
MeSH Terms :
Dexamethasone*/therapeutic use
Disease Models, Animal*
Glucocorticoids*/therapeutic use
Noise*/adverse effects
Tinnitus*/diagnosis
Tinnitus*/drug therapy
Tinnitus*/etiology
Acoustics ; Acute Disease ; Animals ; Evoked Potentials, Auditory, Brain Stem ; Male ; Rats
Czasopismo naukowe
Tytuł :
Comparison of intraosseous and submucosal dexamethasone injection in mandibular third molar surgery: a split-mouth randomized clinical trial.
Autorzy :
Kaewkumnert S; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Phithaksinsuk K; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Changpoo C; Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Nochit N; Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Muensaiyat Y; Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Wilaipornsawai S; Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Piriyaphokai U; Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Powcharoen W; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand. Electronic address: .
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Źródło :
International journal of oral and maxillofacial surgery [Int J Oral Maxillofac Surg] 2020 Apr; Vol. 49 (4), pp. 529-535. Date of Electronic Publication: 2019 Oct 25.
Typ publikacji :
Journal Article; Randomized Controlled Trial
Journal Info :
Publisher: Churchill Livingstone Country of Publication: Denmark NLM ID: 8605826 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-0020 (Electronic) Linking ISSN: 09015027 NLM ISO Abbreviation: Int J Oral Maxillofac Surg Subsets: Dentistry; MEDLINE
MeSH Terms :
Dexamethasone*
Tooth, Impacted*
Anti-Inflammatory Agents ; Edema ; Humans ; Molar, Third ; Pain Measurement ; Pain, Postoperative ; Prospective Studies ; Tooth Extraction ; Trismus
Czasopismo naukowe
Tytuł :
Effect of Intraoperative Dexamethasone on Major Complications and Mortality Among Infants Undergoing Cardiac Surgery: The DECISION Randomized Clinical Trial.
Autorzy :
Lomivorotov V; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.; Novosibirsk State University, Novosibirsk, Russia.
Kornilov I; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.
Boboshko V; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.
Shmyrev V; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.
Bondarenko I; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.
Soynov I; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.
Voytov A; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.
Polyanskih S; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.
Strunin O; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.
Bogachev-Prokophiev A; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.
Landoni G; IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.
Nigro Neto C; Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
Oliveira Nicolau G; Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
Saurith Izquierdo L; Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
Nogueira Nascimento V; Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
Wen Z; Shanghai Jiaotong University School of Medicine, Shanghai Children's Medical Center, Shanghai Shi, China.
Renjie H; Shanghai Jiaotong University School of Medicine, Shanghai Children's Medical Center, Shanghai Shi, China.
Haibo Z; Shanghai Jiaotong University School of Medicine, Shanghai Children's Medical Center, Shanghai Shi, China.
Bazylev V; Federal Centre of Cardiovascular Surgery, Penza, Russian Federation.
Evdokimov M; Federal Centre of Cardiovascular Surgery, Penza, Russian Federation.
Sulejmanov S; Federal Centre of Cardiovascular Surgery, Penza, Russian Federation.
Chernogrivov A; Federal Centre of Cardiovascular Surgery, Penza, Russian Federation.
Ponomarev D; E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.
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Źródło :
JAMA [JAMA] 2020 Jun 23; Vol. 323 (24), pp. 2485-2492.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info :
Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Cardiac Surgical Procedures*/mortality
Intraoperative Care*
Dexamethasone/*therapeutic use
Glucocorticoids/*therapeutic use
Heart Defects, Congenital/*surgery
Postoperative Cognitive Complications/*prevention & control
Cardiopulmonary Bypass ; Dexamethasone/adverse effects ; Double-Blind Method ; Female ; Glucocorticoids/adverse effects ; Humans ; Infant ; Infant, Newborn ; Male ; Postoperative Cognitive Complications/mortality
Czasopismo naukowe
Tytuł :
Eagle syndrome after a fracture of complete ossified stylohyoid ligament from indirect trauma treated using local steroid injection: A case report.
Autorzy :
Lee YW; Department of Otorhinolaryngology-Head and Neck Surgery, Veterans Health Service Daejeon Hospital.
Chung J; Department of Anesthesiology and Pain medicine, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Daejeon.; Department of Anesthesiology and Pain medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Jun 19; Vol. 99 (25), pp. e20818.
Typ publikacji :
Case Reports; Journal Article
Journal Info :
Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Dexamethasone/*therapeutic use
Fractures, Bone/*complications
Hyoid Bone/*injuries
Ligaments, Articular/*injuries
Ossification, Heterotopic/*diagnosis
Temporal Bone/*abnormalities
Aged ; Dexamethasone/administration & dosage ; Humans ; Ligaments, Articular/pathology ; Male ; Ossification, Heterotopic/drug therapy ; Ossification, Heterotopic/etiology
SCR Disease Name :
Eagle syndrome
Czasopismo naukowe
Tytuł :
Dexamethasone solution and dexamethasone in Mucolox for the treatment of oral lichen planus: a preliminary study.
Autorzy :
Villa A; Associate Surgeon, Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA, USA; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA. Electronic address: .
Sankar V; Associate Surgeon, Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA, USA; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA.
Bassani G; Professional Compounding Centers of America, Houston, TX, USA.
Johnson LB; Associate Surgeon, Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA, USA; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA.
Sroussi H; Associate Surgeon, Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA, USA; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA.
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Źródło :
Oral surgery, oral medicine, oral pathology and oral radiology [Oral Surg Oral Med Oral Pathol Oral Radiol] 2020 Jun; Vol. 129 (6), pp. 585-590. Date of Electronic Publication: 2020 Mar 25.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial
Journal Info :
Publisher: Elsevier Country of Publication: United States NLM ID: 101576782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-4411 (Electronic) NLM ISO Abbreviation: Oral Surg Oral Med Oral Pathol Oral Radiol Subsets: Dentistry; MEDLINE
MeSH Terms :
Anti-Inflammatory Agents*/therapeutic use
Dexamethasone*/therapeutic use
Lichen Planus, Oral*
Mouth Diseases*
Aged ; Aged, 80 and over ; Humans ; Middle Aged
Czasopismo naukowe
Tytuł :
Multiple versus single doses of dexamethasone in total hip arthroplasty: A protocol of randomized controlled trial.
Autorzy :
Zhang B; Department of Anesthesiology.
Sun S; Department of Operation room, Panzhihua Central Hospital.
Sheng B; Department of Anesthesiology, West China Second University Hospital, Sichuan University, Sichuan Province, China.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 May; Vol. 99 (19), pp. e20147.
Typ publikacji :
Clinical Trial Protocol; Journal Article; Randomized Controlled Trial
Journal Info :
Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Arthroplasty, Replacement, Hip/*methods
Dexamethasone/*therapeutic use
Pain, Postoperative/*drug therapy
Administration, Intravenous ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Inflammatory Agents/administration & dosage ; Dexamethasone/administration & dosage ; Double-Blind Method ; Drug Administration Schedule ; Female ; Humans ; Length of Stay ; Male ; Middle Aged ; Pain Measurement ; Prospective Studies ; Range of Motion, Articular ; Young Adult
Czasopismo naukowe
Tytuł :
The synergetic effect of bioactive molecule-loaded electrospun core-shell fibres for reconstruction of critical-sized calvarial bone defect-The effect of synergetic release on bone Formation.
Autorzy :
Wu Z; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.; Department of Periodontology and Implantology, Stomatological Hospital, Southern Medical University, Guangzhou, China.
Bao C; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Zhou S; Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, China.
Yang T; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Wang L; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Li M; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Li L; Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, China.
Luo E; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Yu Y; Department of Biomedical Engineering, Tufts University, Medford, MA, USA.
Wang Y; Department of Biomedical Engineering, Tufts University, Medford, MA, USA.
Guo X; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Liu X; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.; Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, China.
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Źródło :
Cell proliferation [Cell Prolif] 2020 Apr; Vol. 53 (4), pp. e12796. Date of Electronic Publication: 2020 Mar 22.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications Country of Publication: England NLM ID: 9105195 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2184 (Electronic) Linking ISSN: 09607722 NLM ISO Abbreviation: Cell Prolif. Subsets: MEDLINE
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Bone Morphogenetic Protein 2/*therapeutic use
Bone Regeneration/*drug effects
Dexamethasone/*therapeutic use
Tissue Scaffolds/*chemistry
Animals ; Anti-Inflammatory Agents/administration & dosage ; Biocompatible Materials/chemistry ; Bone Morphogenetic Protein 2/administration & dosage ; Cells, Cultured ; Dexamethasone/administration & dosage ; Drug Synergism ; Female ; Humans ; Osteogenesis/drug effects ; Rats, Sprague-Dawley ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/therapeutic use ; Skull/drug effects ; Skull/injuries
Czasopismo naukowe
Tytuł :
Effect of intravenous dexamethasone on the anaesthetic characteristics of peripheral nerve block: a double-blind, randomised controlled, dose-response volunteer study.
Autorzy :
Short A; Wrightington, Wigan and Leigh NHS Foundation Trust, Wigan, UK. Electronic address: .
El-Boghdadly K; Guys and St Thomas's NHS Foundation Trust, London, UK; King's College London, London, UK.
Clarke H; Toronto General Hospital, Toronto, Canada.
Komaba T; Toronto Western Hospital, Toronto, ON, Canada.
Jin R; Toronto Western Hospital, Toronto, ON, Canada.
Chin KJ; Toronto Western Hospital, Toronto, ON, Canada.
Chan V; Toronto Western Hospital, Toronto, ON, Canada.
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Źródło :
British journal of anaesthesia [Br J Anaesth] 2020 Jan; Vol. 124 (1), pp. 92-100. Date of Electronic Publication: 2019 Nov 09.
Typ publikacji :
Journal Article; Randomized Controlled Trial
Journal Info :
Publisher: Elsevier Country of Publication: England NLM ID: 0372541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-6771 (Electronic) Linking ISSN: 00070912 NLM ISO Abbreviation: Br J Anaesth Subsets: MEDLINE
MeSH Terms :
Adjuvants, Anesthesia*/administration & dosage
Adjuvants, Anesthesia*/adverse effects
Dexamethasone*/administration & dosage
Dexamethasone*/adverse effects
Peripheral Nerves*
Nerve Block/*methods
Administration, Intravenous ; Adult ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Double-Blind Method ; Female ; Hand Strength ; Healthy Volunteers ; Humans ; Male ; Median Nerve ; Middle Aged ; Nerve Block/adverse effects ; Pain Threshold/drug effects ; Sensation/drug effects ; Thermosensing/drug effects ; Young Adult
Czasopismo naukowe

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