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Tytuł :
Special AT-rich sequence-binding protein 2 (Satb2) synergizes with Bmp9 and is essential for osteo/odontogenic differentiation of mouse incisor mesenchymal stem cells.
Autorzy :
Chen Q; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Zheng L; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Zhang Y; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Huang X; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Wang F; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Li S; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Yang Z; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Liang F; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Hu J; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Jiang Y; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Li Y; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Zhou P; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Luo W; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Zhang H; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
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Źródło :
Cell proliferation [Cell Prolif] 2021 Apr; Vol. 54 (4), pp. e13016. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Growth Differentiation Factor 2/*metabolism
Matrix Attachment Region Binding Proteins/*metabolism
Mesenchymal Stem Cells/*cytology
Odontoblasts/*cytology
Transcription Factors/*metabolism
Adenoviridae/genetics ; Animals ; Bone Regeneration ; Cell Adhesion ; Cell Line ; Cell Proliferation ; Cell Self Renewal ; Genetic Vectors/genetics ; Genetic Vectors/metabolism ; Growth Differentiation Factor 2/genetics ; Hydrogels/chemistry ; Incisor/cytology ; Matrix Attachment Region Binding Proteins/antagonists & inhibitors ; Matrix Attachment Region Binding Proteins/genetics ; Mesenchymal Stem Cells/metabolism ; Mice ; Mice, Inbred C57BL ; Odontoblasts/metabolism ; RNA Interference ; RNA, Small Interfering/metabolism ; Tissue Scaffolds/chemistry ; Transcription Factors/antagonists & inhibitors ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Potential Roles of Bone Morphogenetic Protein 9 in the Odontogenic Differentiation of Dental Pulp Cells.
Autorzy :
Li X; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Wang L; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Su Q; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Ye L; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Zhou X; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Zhang L; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Song D; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address: .
Huang D; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address: .
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Źródło :
Journal of endodontics [J Endod] 2021 Mar; Vol. 47 (3), pp. 436-443. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article
MeSH Terms :
Dental Pulp*
Growth Differentiation Factor 2*/genetics
Alkaline Phosphatase ; Animals ; Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; Extracellular Matrix Proteins/genetics ; In Situ Hybridization, Fluorescence ; Odontoblasts ; Odontogenesis/genetics ; Phosphoproteins/genetics ; Rats
Czasopismo naukowe
Tytuł :
RORα is a critical checkpoint for T cell and ILC2 commitment in the embryonic thymus.
Autorzy :
Ferreira ACF; MRC Laboratory of Molecular Biology, Cambridge, UK. .
Szeto ACH; MRC Laboratory of Molecular Biology, Cambridge, UK.
Heycock MWD; MRC Laboratory of Molecular Biology, Cambridge, UK.
Clark PA; MRC Laboratory of Molecular Biology, Cambridge, UK.
Walker JA; MRC Laboratory of Molecular Biology, Cambridge, UK.; AstraZeneca, Aaron Klug Building, Cambridge, UK.
Crisp A; MRC Laboratory of Molecular Biology, Cambridge, UK.
Barlow JL; MRC Laboratory of Molecular Biology, Cambridge, UK.; Department of Biology, University of York, York, UK.
Kitching S; MRC Laboratory of Molecular Biology, Cambridge, UK.
Lim A; MRC Laboratory of Molecular Biology, Cambridge, UK.; Theolytics Ltd, Oxford, UK.
Gogoi M; MRC Laboratory of Molecular Biology, Cambridge, UK.
Berks R; MRC Laboratory of Molecular Biology, Cambridge, UK.
Daly M; MRC Laboratory of Molecular Biology, Cambridge, UK.
Jolin HE; MRC Laboratory of Molecular Biology, Cambridge, UK.
McKenzie ANJ; MRC Laboratory of Molecular Biology, Cambridge, UK. .
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Źródło :
Nature immunology [Nat Immunol] 2021 Feb; Vol. 22 (2), pp. 166-178. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Cell Lineage*
Immunity, Innate*
CD4-Positive T-Lymphocytes/*metabolism
CD8-Positive T-Lymphocytes/*metabolism
Nuclear Receptor Subfamily 1, Group F, Member 1/*metabolism
Thymocytes/*metabolism
Thymus Gland/*metabolism
Animals ; Basic-Leucine Zipper Transcription Factors/genetics ; Basic-Leucine Zipper Transcription Factors/metabolism ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cell Movement ; Cells, Cultured ; Coculture Techniques ; Female ; Gene Expression Regulation, Developmental ; Inhibitor of Differentiation Protein 2/genetics ; Inhibitor of Differentiation Protein 2/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nuclear Receptor Subfamily 1, Group F, Member 1/genetics ; Organ Culture Techniques ; Phenotype ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Signal Transduction ; Thymocytes/immunology ; Thymus Gland/embryology ; Thymus Gland/immunology ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism
Czasopismo naukowe
Tytuł :
Induction of mesenchymal stem cell‑like transformation in rat primary glial cells using hypoxia, mild hypothermia and growth factors.
Autorzy :
Wei H; Department of Health Care for Cadres, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Zhou W; Department of Prevention and Health Care, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Hu G; Institute of Clinical Medicine, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Shi C; Department of Rheumatology and Immunology, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Feb; Vol. 23 (2). Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Hypothermia*
Epidermal Growth Factor/*pharmacology
Fibroblast Growth Factor 2/*pharmacology
Neuroglia/*metabolism
Animals ; Antigens, Differentiation/biosynthesis ; Cell Hypoxia ; Female ; Male ; Mesenchymal Stem Cells ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
CD74 regulates cellularity and maturation of medullary thymic epithelial cells partially by activating the canonical NF-κB signaling pathway.
Autorzy :
Wang HX; Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Transplantation Biology Research Division, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Zhang Q; Transplantation Biology Research Division, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Zhang J; Transplantation Biology Research Division, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Luan R; Transplantation Biology Research Division, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Liang Z; Transplantation Biology Research Division, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Tan L; Department of Urological Organ Transplantation, Center of Organ Transplantation, The Second Xiangya Hospital of Central South University, Changsha, China.
Xu Y; Transplantation Biology Research Division, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Zhang P; Transplantation Biology Research Division, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Zheng L; Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhao Y; Transplantation Biology Research Division, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Qiu YR; Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 May; Vol. 35 (5), pp. e21535.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Gene Expression Regulation*
Antigens, Differentiation, B-Lymphocyte/*physiology
Epithelial Cells/*pathology
Histocompatibility Antigens Class II/*physiology
Lymphocyte Activation/*immunology
NF-kappa B/*metabolism
Thymus Gland/*pathology
Animals ; Epithelial Cells/immunology ; Epithelial Cells/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; NF-kappa B/genetics ; Signal Transduction ; Thymus Gland/immunology ; Thymus Gland/metabolism
Czasopismo naukowe
Tytuł :
Osteogenic differentiation cues of the bone morphogenetic protein-9 (BMP-9) and its recent advances in bone tissue regeneration.
Autorzy :
Bharadwaz A; Biomedical Engineering Program, Department of Bioengineering, College of Engineering, The University of Toledo, Toledo, OH, USA.
Jayasuriya AC; Biomedical Engineering Program, Department of Bioengineering, College of Engineering, The University of Toledo, Toledo, OH, USA; Department of Orthopaedic Surgery, College of Medicine and Life Sciences, The University of Toledo, Toledo, OH, USA. Electronic address: .
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Źródło :
Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2021 Jan; Vol. 120, pp. 111748. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Growth Differentiation Factor 2*
Osteogenesis*
Bone Morphogenetic Protein 2 ; Bone Morphogenetic Proteins ; Bone Regeneration ; Cell Differentiation ; Cues ; Osteoblasts
Czasopismo naukowe
Tytuł :
Fibroblastic differentiation of mesenchymal stem/stromal cells (MSCs) is enhanced by hypoxia in 3D cultures treated with bone morphogenetic protein 6 (BMP6) and growth and differentiation factor 5 (GDF5).
Autorzy :
Lui H; Griffith University, School of Medicine, Gold Coast, Queensland, Australia; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, United States.
Denbeigh J; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, United States.
Vaquette C; The University of Queensland, School of Dentistry, Brisbane, Queensland, Australia.
Tran HM; The University of Queensland, School of Dentistry, Brisbane, Queensland, Australia.
Dietz AB; Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, United States.
Cool SM; Glycotherapeutics Group, Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore.
Dudakovic A; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, United States; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States.
Kakar S; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, United States.
van Wijnen AJ; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, United States; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jul 01; Vol. 788, pp. 145662. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Morphogenetic Protein 6/*pharmacology
Cell Culture Techniques/*methods
Fibroblasts/*cytology
Growth Differentiation Factor 5/*pharmacology
Mesenchymal Stem Cells/*cytology
Bioreactors ; Cell Differentiation/drug effects ; Cell Hypoxia/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Extracellular Matrix/genetics ; Extracellular Matrix/metabolism ; Fibroblasts/chemistry ; Fibroblasts/drug effects ; Gene Expression Regulation/drug effects ; Humans ; Mesenchymal Stem Cells/chemistry ; Mesenchymal Stem Cells/drug effects ; Tissue Scaffolds
Czasopismo naukowe
Tytuł :
Bone morphogenetic protein 9 (BMP9) directly induces Notch effector molecule Hes1 through the SMAD signaling pathway in osteoblasts.
Autorzy :
Seong CH; Department of Oral and Maxillofacial Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.; Department of Oral Biochemistry, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.
Chiba N; Department of Oral Biochemistry, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.
Kusuyama J; Department of Oral Biochemistry, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.; Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, Japan.
Subhan Amir M; Department of Oral and Maxillofacial Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.; Department of Oral Biochemistry, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Airlangga University, Surabaya, Indonesia.
Eiraku N; Department of Periodontology, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.
Yamashita S; Department of Oral Biochemistry, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.
Ohnishi T; Department of Oral Biochemistry, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.
Nakamura N; Department of Oral and Maxillofacial Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.
Matsuguchi T; Department of Oral Biochemistry, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.
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Źródło :
FEBS letters [FEBS Lett] 2021 Feb; Vol. 595 (3), pp. 389-403. Date of Electronic Publication: 2020 Dec 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Growth Differentiation Factor 2/*genetics
Osteoblasts/*metabolism
Signal Transduction/*genetics
Smad7 Protein/*genetics
Transcription Factor HES-1/*genetics
Animals ; Animals, Newborn ; Autocrine Communication ; Base Sequence ; Cell Differentiation ; Feedback, Physiological ; Gene Expression Regulation, Developmental ; Growth Differentiation Factor 2/metabolism ; Humans ; Mice ; Mice, Inbred C57BL ; Osteoblasts/cytology ; Osteocalcin/genetics ; Osteocalcin/metabolism ; Osteogenesis/genetics ; Primary Cell Culture ; Promoter Regions, Genetic ; Ribosomal Proteins/genetics ; Ribosomal Proteins/metabolism ; Skull/cytology ; Skull/metabolism ; Smad6 Protein/genetics ; Smad6 Protein/metabolism ; Smad7 Protein/metabolism ; Transcription Factor HES-1/metabolism
Czasopismo naukowe
Tytuł :
Growth differentiation factor 5 in cartilage and osteoarthritis: A possible therapeutic candidate.
Autorzy :
Sun K; Department of Orthopedics, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Guo J; Department of Orthopedics, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Yao X; Department of Orthopedics, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Guo Z; Department of Orthopedics, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Guo F; Department of Orthopedics, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
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Źródło :
Cell proliferation [Cell Prolif] 2021 Mar; Vol. 54 (3), pp. e12998. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Chondrocytes/*metabolism
Growth Differentiation Factor 5/*metabolism
Osteoarthritis/*drug therapy
Osteoarthritis/*metabolism
Animals ; Cartilage Diseases/drug therapy ; Cartilage, Articular/drug effects ; Cartilage, Articular/metabolism ; Cell Differentiation/physiology ; Growth Differentiation Factor 5/genetics ; Growth Differentiation Factor 5/pharmacology ; Humans
Czasopismo naukowe
Tytuł :
Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9.
Autorzy :
Rodriguez E; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
Boelaars K; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
Brown K; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
Eveline Li RJ; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
Kruijssen L; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
Bruijns SCM; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
van Ee T; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
Schetters STT; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
Crommentuijn MHW; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
van der Horst JC; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
van Grieken NCT; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pathology, Amsterdam, Netherlands.
van Vliet SJ; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
Kazemier G; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Surgery, Cancer Center Amsterdam, Amsterdam, Netherlands.
Giovannetti E; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam, Netherlands.; Cancer Pharmacology Lab, AIRC Start-Up Unit, Fondazione Pisana per la Scienza, Pisa, Italy.
Garcia-Vallejo JJ; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
van Kooyk Y; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 24; Vol. 12 (1), pp. 1270. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*metabolism
Antigens, Differentiation, Myelomonocytic/*metabolism
Lectins/*metabolism
Macrophages/*cytology
Macrophages/*metabolism
Monocytes/*cytology
Monocytes/*metabolism
Pancreas/*metabolism
Pancreatic Neoplasms/*metabolism
Sialic Acid Binding Immunoglobulin-like Lectins/*metabolism
Sialic Acids/*pharmacology
Antigens, CD/genetics ; Antigens, Differentiation, Myelomonocytic/genetics ; Cell Differentiation/drug effects ; Cell Line, Tumor ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; Humans ; Lectins/genetics ; Macrophages/drug effects ; Monocytes/drug effects ; Phosphorylation/drug effects ; Sialic Acid Binding Immunoglobulin-like Lectins/genetics
SCR Disease Name :
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł :
Adhesion, intracellular signalling and osteogenic differentiation of mesenchymal progenitor cells and preosteoblasts on poly(epsilon)caprolactone films functionalized by peptides derived from fibronectin and/or BMP-9.
Autorzy :
Jann J; Cell-Biomaterial Biohybrid Systems, Department of Chemical and Biotechnological Engineering, Université de Sherbrooke, 2500 boul. de l'Université, Sherbrooke, Québec J1K 2R1, Canada. Electronic address: .
Drevelle O; Thermal Plasma and Nanomaterial Synthesis Laboratory, Department of Chemical and Biotechnological Engineering, Université de Sherbrooke, 2500 boul. de l'Université, Sherbrooke, Québec J1K 2R1, Canada. Electronic address: .
Lauzon MA; 3D Cell Culture Systems Laboratory, Department of Chemical and Biotechnological Engineering, Université de Sherbrooke, 2500 boul. de l'Université, Sherbrooke, Québec J1K 2R1, Canada. Electronic address: .
Faucheux N; Cell-Biomaterial Biohybrid Systems, Department of Chemical and Biotechnological Engineering, Université de Sherbrooke, 2500 boul. de l'Université, Sherbrooke, Québec J1K 2R1, Canada; Clinical Research Centre of Centre Hospitalier Universitaire de Sherbrooke, 12e Avenue N, Sherbrooke, Québec J1H 5N4, Canada. Electronic address: .
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Źródło :
Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2020 Sep; Vol. 114, pp. 111088. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
Growth Differentiation Factor 2*
Mesenchymal Stem Cells*
Alkaline Phosphatase ; Bone Morphogenetic Protein 2 ; Caproates ; Cell Differentiation ; Fibronectins ; Lactones ; Osteoblasts ; Osteogenesis ; Peptides
Czasopismo naukowe
Tytuł :
CD226 deficiency attenuates the homeostasis and suppressive capacity of Tr1 cells.
Autorzy :
Wang N; Department of Immunology, the Fourth Military Medical University, Xi'an 710032, China; Department of Immunology, Xi'an Medical University, No.1, Xinwang Road, Xi'an 710021, China.
Chen P; Department of Immunology, the Fourth Military Medical University, Xi'an 710032, China; Medical College of Yan'an University, No.580, Shengdi Road, Yan'an 716000, China; Department of Neurology, Xianyang Hospital of Yan'an University, No.38, Wenlin Road, Xianyang 712000, China.
Song Y; Department of Immunology, the Fourth Military Medical University, Xi'an 710032, China.
Shen Y; Department of Immunology, the Fourth Military Medical University, Xi'an 710032, China.
Li J; Department of Immunology, the Fourth Military Medical University, Xi'an 710032, China; Faculty of Medicine, Northwest University, Xi'an 710069, China.
Li X; Department of Immunology, the Fourth Military Medical University, Xi'an 710032, China; Medical College of Yan'an University, No.580, Shengdi Road, Yan'an 716000, China.
Fang L; Department of Immunology, the Fourth Military Medical University, Xi'an 710032, China. Electronic address: .
Chen L; Department of Immunology, the Fourth Military Medical University, Xi'an 710032, China; Faculty of Medicine, Northwest University, Xi'an 710069, China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2021 Apr; Vol. 132, pp. 192-198. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Differentiation, T-Lymphocyte/*immunology
Homeostasis/*immunology
T-Lymphocytes, Regulatory/*immunology
Animals ; Apoptosis/immunology ; Cell Differentiation/immunology ; Cell Proliferation/physiology ; Interleukin-10/immunology ; Interleukin-2/immunology ; Lymphocyte Activation/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; STAT5 Transcription Factor/immunology ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł :
Expression and Prognostic Significance of CD47-SIRPA Macrophage Checkpoint Molecules in Colorectal Cancer.
Autorzy :
Sugimura-Nagata A; Division of Gastroenterology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Koshino A; Division of Gastroenterology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Inoue S; Division of Gastroenterology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Matsuo-Nagano A; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Komura M; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Riku M; Department of Pathology, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Ito H; Department of Pathology, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Inoko A; Department of Pathology, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Murakami H; Department of Pathology, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Ebi M; Division of Gastroenterology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Ogasawara N; Division of Gastroenterology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Tsuzuki T; Surgical Pathology, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Takahashi S; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Kasugai K; Division of Gastroenterology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Kasai K; Department of Pathology, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Inaguma S; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.; Department of Pathology, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.; Department of Pathology, Nagoya City East Medical Center, Nagoya 464-8547, Japan.; Educational Research Center for Advanced Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 07; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 07.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, Differentiation/*metabolism
CD47 Antigen/*metabolism
Colorectal Neoplasms/*mortality
Colorectal Neoplasms/*pathology
Receptors, Immunologic/*metabolism
Aged ; Aged, 80 and over ; Antigens, CD/metabolism ; Antigens, Differentiation, Myelomonocytic/metabolism ; Biomarkers, Tumor/metabolism ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/surgery ; Female ; Humans ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Middle Aged ; Prognosis ; Receptors, Cell Surface/metabolism ; Survival Analysis
Czasopismo naukowe
Tytuł :
BMP9 exhibits dual and coupled roles in inducing osteogenic and angiogenic differentiation of mesenchymal stem cells.
Autorzy :
Xiao H; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Wang X; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Wang C; Department of Computational and Applied Mathematics, Rice University, Houston, TX 77005, U.S.A.
Dai G; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Zhu Z; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Gao S; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
He B; Key Laboratory for Biochemistry and Molecular Pharmacology of Chongqing, Chongqing Medical University, Chongqing 400016, China.
Liao J; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Huang W; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
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Źródło :
Bioscience reports [Biosci Rep] 2020 Jun 26; Vol. 40 (6).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Neovascularization, Physiologic*
Osteogenesis*
Growth Differentiation Factor 2/*metabolism
Mesenchymal Stem Cells/*metabolism
Animals ; Gene Expression Regulation ; Growth Differentiation Factor 2/genetics ; HEK293 Cells ; Humans ; Mesenchymal Stem Cell Transplantation ; Mice ; Mice, Nude ; Platelet Endothelial Cell Adhesion Molecule-1/genetics ; Platelet Endothelial Cell Adhesion Molecule-1/metabolism ; Signal Transduction ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł :
Effect of cAMP Signaling Regulation in Osteogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells.
Autorzy :
Rumiński S; Department of Histology and Embryology, Center for Biostructure Research, Medical University of Warsaw, 02-004 Warsaw, Poland.; Postgraduate School of Molecular Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland.
Kalaszczyńska I; Department of Histology and Embryology, Center for Biostructure Research, Medical University of Warsaw, 02-004 Warsaw, Poland.; Laboratory for Cell Research and Application, Medical University of Warsaw, Warsaw 02-097, Poland.
Lewandowska-Szumieł M; Department of Histology and Embryology, Center for Biostructure Research, Medical University of Warsaw, 02-004 Warsaw, Poland.; Laboratory for Cell Research and Application, Medical University of Warsaw, Warsaw 02-097, Poland.
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Źródło :
Cells [Cells] 2020 Jun 30; Vol. 9 (7). Date of Electronic Publication: 2020 Jun 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Signal Transduction*
Adipose Tissue/*cytology
Cyclic AMP/*metabolism
Mesenchymal Stem Cells/*metabolism
Osteoblasts/*metabolism
Cells, Cultured ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Cyclic AMP-Dependent Protein Kinases/genetics ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Humans ; Inhibitor of Differentiation Protein 2/genetics ; Inhibitor of Differentiation Protein 2/metabolism ; Integrin-Binding Sialoprotein/genetics ; Integrin-Binding Sialoprotein/metabolism ; Mesenchymal Stem Cells/cytology ; Osteoblasts/cytology ; Osteocalcin/genetics ; Osteocalcin/metabolism ; Sp7 Transcription Factor/genetics ; Sp7 Transcription Factor/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling.
Autorzy :
Theilmann AL; Department of Biomedical and Molecular Sciences (A.L.T., L.G.H., L.R.H., M.K.M.W., D.V.C., J.L.M., D.H.M., M.L.O.), Queen's University, Kingston, Canada.
Hawke LG; Department of Biomedical and Molecular Sciences (A.L.T., L.G.H., L.R.H., M.K.M.W., D.V.C., J.L.M., D.H.M., M.L.O.), Queen's University, Kingston, Canada.
Hilton LR; Department of Biomedical and Molecular Sciences (A.L.T., L.G.H., L.R.H., M.K.M.W., D.V.C., J.L.M., D.H.M., M.L.O.), Queen's University, Kingston, Canada.
Whitford MKM; Department of Biomedical and Molecular Sciences (A.L.T., L.G.H., L.R.H., M.K.M.W., D.V.C., J.L.M., D.H.M., M.L.O.), Queen's University, Kingston, Canada.
Cole DV; Department of Biomedical and Molecular Sciences (A.L.T., L.G.H., L.R.H., M.K.M.W., D.V.C., J.L.M., D.H.M., M.L.O.), Queen's University, Kingston, Canada.
Mackeil JL; Department of Biomedical and Molecular Sciences (A.L.T., L.G.H., L.R.H., M.K.M.W., D.V.C., J.L.M., D.H.M., M.L.O.), Queen's University, Kingston, Canada.
Dunham-Snary KJ; Department of Medicine (K.J.D.-S., J.M., P.D.J., S.L.A., M.L.O.), Queen's University, Kingston, Canada.
Mewburn J; Department of Medicine (K.J.D.-S., J.M., P.D.J., S.L.A., M.L.O.), Queen's University, Kingston, Canada.
James PD; Department of Medicine (K.J.D.-S., J.M., P.D.J., S.L.A., M.L.O.), Queen's University, Kingston, Canada.
Maurice DH; Department of Biomedical and Molecular Sciences (A.L.T., L.G.H., L.R.H., M.K.M.W., D.V.C., J.L.M., D.H.M., M.L.O.), Queen's University, Kingston, Canada.
Archer SL; Department of Medicine (K.J.D.-S., J.M., P.D.J., S.L.A., M.L.O.), Queen's University, Kingston, Canada.
Ormiston ML; Department of Surgery (M.L.O.), Queen's University, Kingston, Canada.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Nov; Vol. 40 (11), pp. 2605-2618. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Morphogenetic Protein Receptors, Type II/*deficiency
Cell Proliferation/*drug effects
Endothelial Cells/*drug effects
Growth Differentiation Factor 2/*pharmacology
Pulmonary Arterial Hypertension/*drug therapy
Adult ; Aged ; Animals ; Bone Morphogenetic Protein Receptors, Type II/genetics ; Case-Control Studies ; Cells, Cultured ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Female ; Growth Differentiation Factor 2/toxicity ; Humans ; Inhibitor of Differentiation Proteins/genetics ; Inhibitor of Differentiation Proteins/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Middle Aged ; Pulmonary Arterial Hypertension/genetics ; Pulmonary Arterial Hypertension/metabolism ; Pulmonary Arterial Hypertension/pathology ; Signal Transduction ; Young Adult
Czasopismo naukowe
Tytuł :
Dectin-1 Stimulation of Hematopoietic Stem and Progenitor Cells Occurs In Vivo and Promotes Differentiation Toward Trained Macrophages via an Indirect Cell-Autonomous Mechanism.
Autorzy :
Bono C; Departamento de Microbiología y Ecología, Universitat de València, Burjassot, Spain.; Estructura de Recerca Interdisciplinar en Biotecnologia i Biomedicina (ERI BIOTECMED), Universitat de València, Burjassot, Spain.
Martínez A; Departamento de Microbiología y Ecología, Universitat de València, Burjassot, Spain.; Estructura de Recerca Interdisciplinar en Biotecnologia i Biomedicina (ERI BIOTECMED), Universitat de València, Burjassot, Spain.
Megías J; Departamento de Patología, Universitat de València, Valencia, Spain.
Gozalbo D; Departamento de Microbiología y Ecología, Universitat de València, Burjassot, Spain.; Estructura de Recerca Interdisciplinar en Biotecnologia i Biomedicina (ERI BIOTECMED), Universitat de València, Burjassot, Spain.
Yáñez A; Departamento de Microbiología y Ecología, Universitat de València, Burjassot, Spain.; Estructura de Recerca Interdisciplinar en Biotecnologia i Biomedicina (ERI BIOTECMED), Universitat de València, Burjassot, Spain.
Gil ML; Departamento de Microbiología y Ecología, Universitat de València, Burjassot, Spain .; Estructura de Recerca Interdisciplinar en Biotecnologia i Biomedicina (ERI BIOTECMED), Universitat de València, Burjassot, Spain.
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Źródło :
MBio [mBio] 2020 Jun 23; Vol. 11 (3). Date of Electronic Publication: 2020 Jun 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Hematopoietic Stem Cells/*cytology
Lectins, C-Type/*metabolism
Macrophages/*cytology
Stem Cells/*cytology
Animals ; Candida albicans/immunology ; Candidiasis/immunology ; Female ; Hematopoietic Stem Cells/drug effects ; Immunity, Innate ; Lectins, C-Type/genetics ; Macrophages/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Myeloid Differentiation Factor 88/metabolism ; Signal Transduction ; Stem Cells/drug effects ; Toll-Like Receptor 2/immunology ; beta-Glucans/administration & dosage
SCR Disease Name :
Systemic candidiasis
Czasopismo naukowe
Tytuł :
BMP9 Reduces Bone Loss in Ovariectomized Mice by Dual Regulation of Bone Remodeling.
Autorzy :
Zhou YM; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, China.
Yang YY; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, China.
Jing YX; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, China.
Yuan TJ; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, China.
Sun LH; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, China.
Tao B; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, China.
Liu JM; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, China.
Zhao HY; Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai, China.
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Źródło :
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2020 May; Vol. 35 (5), pp. 978-993. Date of Electronic Publication: 2020 Jan 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Resorption*
Growth Differentiation Factor 2*
Animals ; Cell Differentiation ; Female ; Mice ; NFATC Transcription Factors ; Osteoblasts ; Osteoclasts ; Osteogenesis ; RANK Ligand
Czasopismo naukowe
Tytuł :
GDF-15 negatively regulates excess erythropoiesis and its overexpression is involved in erythroid hyperplasia.
Autorzy :
Ranjbaran R; Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Abbasi M; Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia. Electronic address: .
Rahimian E; Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Dehbidi GR; Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Seyyedi N; Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Zare F; Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Behzad-Behbahani A; Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2020 Dec 15; Vol. 397 (2), pp. 112346. Date of Electronic Publication: 2020 Oct 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Erythropoiesis*
Erythroid Precursor Cells/*pathology
Growth Differentiation Factor 15/*metabolism
Hematopoietic Stem Cells/*pathology
Hyperplasia/*pathology
beta-Thalassemia/*pathology
Case-Control Studies ; Cell Differentiation ; Erythroid Precursor Cells/metabolism ; Hematopoietic Stem Cells/metabolism ; Humans ; Hyperplasia/metabolism ; Stem Cell Factor/metabolism ; Transforming Growth Factor beta/metabolism ; beta-Thalassemia/metabolism
Czasopismo naukowe
Tytuł :
Relationship between plasma growth differentiation factor-15 levels and diabetic retinopathy in individuals with type 2 diabetes.
Autorzy :
Chung JO; Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonnam National University Medical School, 8 Hak-Dong, Dong-Gu, Gwangju, 501-757, Republic of Korea.
Park SY; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chonnam National University Medical School, 8 Hak-Dong, Dong-Gu, Gwangju, 501-757, Republic of Korea. .
Cho DH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonnam National University Medical School, 8 Hak-Dong, Dong-Gu, Gwangju, 501-757, Republic of Korea.
Chung DJ; Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonnam National University Medical School, 8 Hak-Dong, Dong-Gu, Gwangju, 501-757, Republic of Korea.
Chung MY; Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonnam National University Medical School, 8 Hak-Dong, Dong-Gu, Gwangju, 501-757, Republic of Korea. .
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 25; Vol. 10 (1), pp. 20568. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2/*metabolism
Diabetic Retinopathy/*metabolism
Growth Differentiation Factor 15/*metabolism
Adult ; Aged ; Cross-Sectional Studies ; Female ; Growth Differentiation Factor 15/blood ; Growth Differentiation Factors/blood ; Growth Differentiation Factors/metabolism ; Humans ; Male ; Middle Aged ; Republic of Korea/epidemiology ; Severity of Illness Index
Czasopismo naukowe

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