Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""DISEASE"" wg kryterium: Temat


Starter badań:

Tytuł :
Molecular biology of Hodgkin lymphoma.
Autorzy :
Weniger MA; Medical Faculty, Institute of Cell Biology (Cancer Research), University of Duisburg-Essen, Essen, Germany.
Küppers R; Medical Faculty, Institute of Cell Biology (Cancer Research), University of Duisburg-Essen, Essen, Germany. .
Pokaż więcej
Źródło :
Leukemia [Leukemia] 2021 Apr; Vol. 35 (4), pp. 968-981. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Disease Susceptibility*
Hodgkin Disease/*etiology
Animals ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; B-Lymphocytes/pathology ; Biomarkers, Tumor ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/immunology ; Cell Transformation, Neoplastic/metabolism ; Disease Management ; Gene Expression Regulation, Neoplastic/drug effects ; Genetic Predisposition to Disease ; Genetic Variation ; Hodgkin Disease/diagnosis ; Hodgkin Disease/metabolism ; Hodgkin Disease/therapy ; Humans ; Immune Evasion ; Signal Transduction/drug effects ; Transcription Factors/metabolism ; Tumor Microenvironment/genetics ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
Prediction of Alzheimer's disease-specific phospholipase c gamma-1 SNV by deep learning-based approach for high-throughput screening.
Autorzy :
Kim SH; Neurodegenerative Disease Research Group, 41062 Daegu, Republic of Korea.; Korea Brain Research Institute, 41062 Daegu, Republic of Korea.
Yang S; Neurodegenerative Disease Research Group, 41062 Daegu, Republic of Korea.; Korea Brain Research Institute, 41062 Daegu, Republic of Korea.
Lim KH; Neurodegenerative Disease Research Group, 41062 Daegu, Republic of Korea.; Korea Brain Research Institute, 41062 Daegu, Republic of Korea.
Ko E; Department of Computer Science, University of Nevada, Las Vegas, NV 89154.
Jang HJ; School of Life Sciences, Ulsan National Institute of Science and Technology, 44919 Ulsan, Republic of Korea.
Kang M; Department of Computer Science, University of Nevada, Las Vegas, NV 89154.
Suh PG; Korea Brain Research Institute, 41062 Daegu, Republic of Korea.
Joo JY; Neurodegenerative Disease Research Group, 41062 Daegu, Republic of Korea; .; Korea Brain Research Institute, 41062 Daegu, Republic of Korea.
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 19; Vol. 118 (3).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Deep Learning*
Genetic Predisposition to Disease*
Alzheimer Disease/*genetics
Phospholipase C gamma/*genetics
Alzheimer Disease/pathology ; Animals ; Computer Simulation ; Disease Models, Animal ; Exons/genetics ; Genome, Human ; Genome-Wide Association Study ; High-Throughput Screening Assays ; Humans ; Mice ; Polymorphism, Single Nucleotide/genetics ; RNA Splicing/genetics ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł :
Why Lyme disease is common in the northern US, but rare in the south: The roles of host choice, host-seeking behavior, and tick density.
Autorzy :
Ginsberg HS; US Geological Survey, Patuxent Wildlife Research Center, Woodward-PSE, University of Rhode Island, Kingston, Rhode Island, United States of America.; Department of Plant Sciences and Entomology, University of Rhode Island, Kingston, Rhode Island, United States of America.
Hickling GJ; Center for Wildlife Health, University of Tennessee Institute of Agriculture, Knoxville, Tennessee, United States of America.
Burke RL; Department of Biology, Hofstra University, Hempstead, New York, United States of America.
Ogden NH; Public Health Risk Sciences Division, National Microbiology Laboratory, Public Health Agency of Canada, Ste-Hyacinthe, Quebec, Canada.
Beati L; US National Tick Collection, Institute for Coastal Plain Science, Georgia Southern University, Statesboro, Georgia, United States of America.
LeBrun RA; Department of Plant Sciences and Entomology, University of Rhode Island, Kingston, Rhode Island, United States of America.
Arsnoe IM; Department of Fisheries and Wildlife, Michigan State University, East Lansing, Michigan, United States of America.
Gerhold R; Center for Wildlife Health, University of Tennessee Institute of Agriculture, Knoxville, Tennessee, United States of America.
Han S; Comparative Medicine and Integrative Biology, Michigan State University, East Lansing, Michigan, United States of America.
Jackson K; Department of Biology, Hofstra University, Hempstead, New York, United States of America.
Maestas L; Center for Wildlife Health, University of Tennessee Institute of Agriculture, Knoxville, Tennessee, United States of America.
Moody T; Center for Wildlife Health, University of Tennessee Institute of Agriculture, Knoxville, Tennessee, United States of America.
Pang G; Department of Fisheries and Wildlife, Michigan State University, East Lansing, Michigan, United States of America.
Ross B; Department of Biology, Hofstra University, Hempstead, New York, United States of America.
Rulison EL; Department of Plant Sciences and Entomology, University of Rhode Island, Kingston, Rhode Island, United States of America.
Tsao JI; Department of Fisheries and Wildlife, Michigan State University, East Lansing, Michigan, United States of America.
Pokaż więcej
Źródło :
PLoS biology [PLoS Biol] 2021 Jan 28; Vol. 19 (1), pp. e3001066. Date of Electronic Publication: 2021 Jan 28 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Disease Vectors*/classification
Host-Seeking Behavior/*physiology
Lyme Disease/*epidemiology
Animals ; Animals, Wild ; Borrelia burgdorferi/physiology ; Climate ; Disease Reservoirs/microbiology ; Disease Reservoirs/statistics & numerical data ; Geography ; Host Specificity/physiology ; Humans ; Lizards/microbiology ; Lyme Disease/transmission ; Mice ; Population Density ; Prevalence ; Rats ; Sciuridae/microbiology ; Shrews/microbiology ; Tick Infestations/epidemiology ; Tick Infestations/microbiology ; Tick Infestations/transmission ; Ticks/microbiology ; United States/epidemiology
Czasopismo naukowe
Tytuł :
IL-17C contributes to NTHi-induced inflammation and lung damage in experimental COPD and is present in sputum during acute exacerbations.
Autorzy :
Vella G; Department of Internal Medicine V - Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Homburg, Germany.
Ritzmann F; Department of Internal Medicine V - Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Homburg, Germany.
Wolf L; Department of Internal Medicine V - Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Homburg, Germany.
Kamyschnikov A; Department of Internal Medicine V - Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Homburg, Germany.
Stodden H; Department of Internal Medicine V - Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Homburg, Germany.
Herr C; Department of Internal Medicine V - Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Homburg, Germany.
Slevogt H; Septomics Research Center, Jena University Hospital, Jena, Germany.
Bals R; Department of Internal Medicine V - Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Homburg, Germany.
Beisswenger C; Department of Internal Medicine V - Pulmonology, Allergology and Respiratory Critical Care Medicine, Saarland University, Homburg, Germany.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2021 Jan 07; Vol. 16 (1), pp. e0243484. Date of Electronic Publication: 2021 Jan 07 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Progression*
Haemophilus influenzae/*physiology
Interleukin-17/*metabolism
Lung/*microbiology
Lung/*pathology
Pneumonia/*microbiology
Pulmonary Disease, Chronic Obstructive/*microbiology
Sputum/*microbiology
Acute Disease ; Aged ; Animals ; Cigarette Smoking/adverse effects ; Cytokines/metabolism ; Female ; Humans ; Male ; Mice, Inbred C57BL ; Neutrophils/pathology
Czasopismo naukowe
Tytuł :
Experimental SARS-CoV-2 Infection of Bank Voles.
Autorzy :
Ulrich L
Michelitsch A
Halwe N
Wernike K
Hoffmann D
Beer M
Pokaż więcej
Źródło :
Emerging infectious diseases [Emerg Infect Dis] 2021 Apr; Vol. 27 (4), pp. 1193-1195.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arvicolinae*
COVID-19*/immunology
COVID-19*/transmission
COVID-19*/virology
Disease Transmission, Infectious*
Rodent Diseases*/immunology
Rodent Diseases*/transmission
Rodent Diseases*/virology
Seroconversion*
Virus Shedding*
Animals ; Antibodies, Viral ; COVID-19 Serological Testing ; Disease Models, Animal ; Disease Susceptibility ; Nasal Mucosa/virology
Czasopismo naukowe
Tytuł :
Characterization of a Mouse Model of Alzheimer's Disease Expressing Aβ4-42 and Human Mutant Tau.
Autorzy :
Zampar S; Department of Psychiatry and Psychotherapy, University Medical Center (UMG), Georg-August-University, D-37075 Göttingen, Germany.
Wirths O; Department of Psychiatry and Psychotherapy, University Medical Center (UMG), Georg-August-University, D-37075 Göttingen, Germany.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 14; Vol. 22 (10). Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Mutation*
Alzheimer Disease/*complications
Amyloid beta-Peptides/*metabolism
Memory Disorders/*etiology
Motor Disorders/*etiology
tau Proteins/*genetics
Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Amyloid beta-Peptides/genetics ; Animals ; Behavior, Animal ; Female ; Humans ; Male ; Memory Disorders/metabolism ; Memory Disorders/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Motor Disorders/metabolism ; Motor Disorders/pathology ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
Update on ocular graft-versus-host disease.
Autorzy :
Nair S; Cornea, Cataract & Refractive Surgery Services, Dr R P Centre, All India Institute of Medical Sciences, New Delhi, India.
Vanathi M; Cornea, Cataract & Refractive Surgery Services, Dr R P Centre, All India Institute of Medical Sciences, New Delhi, India.
Mukhija R; Cornea, Cataract & Refractive Surgery Services, Dr R P Centre, All India Institute of Medical Sciences, New Delhi, India.
Tandon R; Cornea, Cataract & Refractive Surgery Services, Dr R P Centre, All India Institute of Medical Sciences, New Delhi, India.
Jain S; Department of Ophthalmology, University of Chicago, USA.
Ogawa Y; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Pokaż więcej
Źródło :
Indian journal of ophthalmology [Indian J Ophthalmol] 2021 May; Vol. 69 (5), pp. 1038-1050.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Dry Eye Syndromes*
Graft vs Host Disease*/diagnosis
Graft vs Host Disease*/etiology
Hematopoietic Stem Cell Transplantation*/adverse effects
Chronic Disease ; Humans ; Meibomian Glands ; Quality of Life ; United States
Czasopismo naukowe
Tytuł :
Patients with inflammatory bowel disease on immunosuppressive drugs: perspectives' on COVID-19 and health care service during the pandemic.
Autorzy :
Moum KM; Faculty of Health Science, University of Southern Denmark, Odense, Denmark.
Moum B; Department of Gastroenterology, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Opheim R; Department of Gastroenterology, Oslo University Hospital, Oslo, Norway.; Department of Health and Society, University of Oslo, Oslo, Norway.
Pokaż więcej
Źródło :
Scandinavian journal of gastroenterology [Scand J Gastroenterol] 2021 May; Vol. 56 (5), pp. 545-551. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/epidemiology
COVID-19*/prevention & control
Colitis, Ulcerative*/drug therapy
Colitis, Ulcerative*/epidemiology
Colitis, Ulcerative*/psychology
Crohn Disease*/drug therapy
Crohn Disease*/epidemiology
Crohn Disease*/psychology
Patient Compliance*/psychology
Patient Compliance*/statistics & numerical data
Patient Preference*
Immunosuppressive Agents/*therapeutic use
Adult ; Attitude to Health ; Communicable Disease Control/methods ; Communicable Disease Control/statistics & numerical data ; Continuity of Patient Care/standards ; Female ; Humans ; Male ; Middle Aged ; Norway/epidemiology ; Physical Distancing ; Remote Consultation/statistics & numerical data ; SARS-CoV-2 ; Self Report
Czasopismo naukowe
Tytuł :
DYNLT1 gene expression is downregulated in whole blood of patients at different Huntington's disease stages.
Autorzy :
Rosseto SM; Graduate Program in Biochemistry and Pharmacology, Health Sciences Center, Federal University of Espírito Santo, Vitória, ES, Brazil.
Alarcon TA; Laboratory of Molecular and Behavioral Neurobiology, Health Sciences Center, Federal University of Espírito Santo, Vitória, ES, Brazil.
Rocha DMC; Department of Pharmaceutical Sciences, Health Sciences Center, Federal University of Espírito Santo, Vitória, ES, 29043-900, Brazil.
Ribeiro FM; Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Ferguson SSG; Department of Cellular and Molecular Medicine, Brain and Mind Research Institute and Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Martins-Silva C; Graduate Program in Biochemistry and Pharmacology, Health Sciences Center, Federal University of Espírito Santo, Vitória, ES, Brazil.; Laboratory of Molecular and Behavioral Neurobiology, Health Sciences Center, Federal University of Espírito Santo, Vitória, ES, Brazil.
Muniz MR; Department of Clinical Medicine, Health Science Center, Federal University of Espírito Santo, Espírito Santo, Brazil.
Costa PF; Department of Physiotherapy, School of Sciences, Santa Casa de Misericordia de Vitoria, Vitória, ES, Brazil.
Guimarães DA; Graduate Program in Biochemistry and Pharmacology, Health Sciences Center, Federal University of Espírito Santo, Vitória, ES, Brazil.; Department of Pharmaceutical Sciences, Health Sciences Center, Federal University of Espírito Santo, Vitória, ES, 29043-900, Brazil.
Pires RGW; Graduate Program in Biochemistry and Pharmacology, Health Sciences Center, Federal University of Espírito Santo, Vitória, ES, Brazil. .; Laboratory of Molecular and Behavioral Neurobiology, Health Sciences Center, Federal University of Espírito Santo, Vitória, ES, Brazil. .; Department of Physiological Sciences, Health Sciences Center, Federal University of Espirito Santo, Vitória, ES, 29043-910, Brazil. .
Pokaż więcej
Źródło :
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2021 May; Vol. 42 (5), pp. 1963-1967. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article
MeSH Terms :
Huntington Disease*/genetics
Animals ; Disease Models, Animal ; Disease Progression ; Dyneins ; Gene Expression ; Humans ; Huntingtin Protein/genetics ; Mice
Czasopismo naukowe
Tytuł :
Composite UHDRS Correlates With Progression of Imaging Biomarkers in Huntington's Disease.
Autorzy :
Estevez-Fraga C; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Scahill RI; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Durr A; Sorbonne Université, Paris Brain Institute (ICM), AP-HP, Inserm, CNRS, Pitié-Salpêtrière University Hospital, Paris, France.
Leavitt BR; Centre for Molecular Medicine and Therapeutics, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
Roos RAC; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Langbehn DR; Department of Psychiatry, University of Iowa, Iowa City, Iowa, USA.
Rees G; Wellcome Centre for Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
Gregory S; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Tabrizi SJ; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Pokaż więcej
Źródło :
Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2021 May; Vol. 36 (5), pp. 1259-1264. Date of Electronic Publication: 2021 Jan 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Huntington Disease*/diagnostic imaging
Huntington Disease*/pathology
White Matter*/diagnostic imaging
White Matter*/pathology
Anisotropy ; Atrophy/pathology ; Biomarkers ; Disease Progression ; Humans ; Magnetic Resonance Imaging
Czasopismo naukowe
Tytuł :
Presymptomatic Crohn's Disease in a Young Patient Diagnosed Just After the Onset of Idiopathic Acute Pancreatitis.
Autorzy :
Endo K; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Hirota M; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Sasaki Y; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Koiwai A; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Nihei K; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Takasu A; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Kawamura K; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Murakami K; Division of Pathology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Murakami K; Division of Pathology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Kogure T; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Meguro T; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Satoh K; Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, Japan.
Pokaż więcej
Źródło :
Internal medicine (Tokyo, Japan) [Intern Med] 2021 Apr 15; Vol. 60 (8), pp. 1205-1210. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Colitis*
Crohn Disease*/complications
Crohn Disease*/diagnosis
Inflammatory Bowel Diseases*
Pancreatitis*/diagnosis
Pancreatitis*/etiology
Acute Disease ; Adolescent ; Child ; Humans ; Male
Czasopismo naukowe
Tytuł :
A Data-Driven Simulation of the Exposure Notification Cascade for Digital Contact Tracing of SARS-CoV-2 in Zurich, Switzerland.
Autorzy :
Menges D; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Aschmann HE; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Moser A; CTU Bern, University of Bern, Bern, Switzerland.
Althaus CL; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
von Wyl V; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.; Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.
Pokaż więcej
Źródło :
JAMA network open [JAMA Netw Open] 2021 Apr 01; Vol. 4 (4), pp. e218184. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/diagnosis
COVID-19*/epidemiology
COVID-19*/prevention & control
COVID-19*/transmission
Computer Simulation*
Contact Tracing*/methods
Contact Tracing*/statistics & numerical data
Disease Notification*/methods
Disease Notification*/statistics & numerical data
Disease Transmission, Infectious*/prevention & control
Disease Transmission, Infectious*/statistics & numerical data
Mobile Applications*
Adult ; Communicable Disease Control/methods ; Communicable Disease Control/organization & administration ; Female ; Humans ; Male ; Quarantine ; SARS-CoV-2/isolation & purification ; Switzerland/epidemiology
Czasopismo naukowe
Tytuł :
Meta-analysis of sample-level dbGaP data reveals novel shared genetic link between body height and Crohn's disease.
Autorzy :
Di Narzo A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York, NY, 10029, USA.; Icahn School of Medicine At Mount Sinai, Icahn Institute for Data Science and Genomic Technology, New York, NY, USA.
Frades I; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York, NY, 10029, USA.; Computational Biology and Systems Biomedicine Research Group, Biodonostia Health Research Institute, San Sebastián, Spain.
Crane HM; Department of Medicine, University of Washington, Seattle, WA, USA.; Center for AIDS Research, University of Washington, Seattle, WA, USA.
Crane PK; Department of Medicine, University of Washington, Seattle, WA, USA.
Hulot JS; Université de Paris, INSERM, PARCC, CIC1418, F-75015, Paris, France.; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kasarskis A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York, NY, 10029, USA.; Icahn School of Medicine At Mount Sinai, Icahn Institute for Data Science and Genomic Technology, New York, NY, USA.; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hart A; Janssen R&D, LLC, 1400 McKean Road, Spring House, PA, USA.
Argmann C; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York, NY, 10029, USA.; Icahn School of Medicine At Mount Sinai, Icahn Institute for Data Science and Genomic Technology, New York, NY, USA.
Dubinsky M; Department of Pediatric Gastroenterology and Nutrition, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Peter I; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York, NY, 10029, USA.; Icahn School of Medicine At Mount Sinai, Icahn Institute for Data Science and Genomic Technology, New York, NY, USA.
Hao K; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York, NY, 10029, USA. .; Icahn School of Medicine At Mount Sinai, Icahn Institute for Data Science and Genomic Technology, New York, NY, USA. .
Pokaż więcej
Źródło :
Human genetics [Hum Genet] 2021 Jun; Vol. 140 (6), pp. 865-877. Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :
Journal Article; Meta-Analysis
MeSH Terms :
Genetic Predisposition to Disease*
Body Height/*genetics
Crohn Disease/*genetics
Diabetes Mellitus, Type 2/*genetics
Intercellular Signaling Peptides and Proteins/*genetics
Myocardial Infarction/*genetics
Adult ; Body Height/immunology ; Child ; Crohn Disease/immunology ; Crohn Disease/pathology ; Databases, Genetic ; Diabetes Mellitus, Type 2/immunology ; Diabetes Mellitus, Type 2/pathology ; Female ; Gene Expression Regulation ; Humans ; Immune Checkpoint Proteins/genetics ; Immune Checkpoint Proteins/immunology ; Immunity, Innate ; Intercellular Signaling Peptides and Proteins/immunology ; Male ; Multifactorial Inheritance/immunology ; Myocardial Infarction/immunology ; Myocardial Infarction/pathology ; Phenotype ; Risk Factors
Czasopismo naukowe
Tytuł :
Effect of compliance with GOLD treatment recommendations on COPD health care resource utilization, cost, and exacerbations among patients with COPD on maintenance therapy.
Autorzy :
Palli SR; Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT.
Zhou S; HealthCore, Wilmington, DE.
Shaikh A; Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT.
Willey VJ; HealthCore, Wilmington, DE.
Pokaż więcej
Źródło :
Journal of managed care & specialty pharmacy [J Manag Care Spec Pharm] 2021 May; Vol. 27 (5), pp. 625-637. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Disease Progression*
Patient Acceptance of Health Care*
Patient Compliance*
Global Health/*trends
Health Care Costs/*trends
Pulmonary Disease, Chronic Obstructive/*therapy
Adrenal Cortex Hormones/economics ; Adrenal Cortex Hormones/therapeutic use ; Aged ; Aged, 80 and over ; Cohort Studies ; Female ; Global Health/economics ; Global Health/standards ; Humans ; Male ; Middle Aged ; Muscarinic Antagonists/economics ; Muscarinic Antagonists/therapeutic use ; Practice Guidelines as Topic/standards ; Pulmonary Disease, Chronic Obstructive/economics ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis Cirrhosis Confirmed by Liver Histology after 14 Years.
Autorzy :
Kawanaka M; Department of General Internal Medicine2, Kawasaki Medical Center, Kawasaki Medical School, Japan.
Nishino K; Department of General Internal Medicine2, Kawasaki Medical Center, Kawasaki Medical School, Japan.
Morimoto Y; Department of General Internal Medicine2, Kawasaki Medical Center, Kawasaki Medical School, Japan.
Ishii K; Department of General Internal Medicine2, Kawasaki Medical Center, Kawasaki Medical School, Japan.
Tanikawa T; Department of General Internal Medicine2, Kawasaki Medical Center, Kawasaki Medical School, Japan.
Urata N; Department of General Internal Medicine2, Kawasaki Medical Center, Kawasaki Medical School, Japan.
Suehiro M; Department of General Internal Medicine2, Kawasaki Medical Center, Kawasaki Medical School, Japan.
Sasai T; Department of General Internal Medicine2, Kawasaki Medical Center, Kawasaki Medical School, Japan.
Haruma K; Department of General Internal Medicine2, Kawasaki Medical Center, Kawasaki Medical School, Japan.
Kawamoto H; Department of General Internal Medicine2, Kawasaki Medical Center, Kawasaki Medical School, Japan.
Pokaż więcej
Źródło :
Internal medicine (Tokyo, Japan) [Intern Med] 2021 May 01; Vol. 60 (9), pp. 1397-1401. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Non-alcoholic Fatty Liver Disease*/complications
Non-alcoholic Fatty Liver Disease*/pathology
Adult ; Biopsy ; Disease Progression ; Female ; Humans ; Liver/pathology ; Liver Cirrhosis/etiology ; Liver Cirrhosis/pathology ; Middle Aged
Czasopismo naukowe
Tytuł :
Metabolic Spectrum of Liver Failure in Type 2 Diabetes and Obesity: From NAFLD to NASH to HCC.
Autorzy :
Kim H; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon 34141, Korea.
Lee DS; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.
An TH; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon 34141, Korea.
Park HJ; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon 34141, Korea.
Kim WK; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon 34141, Korea.
Bae KH; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon 34141, Korea.
Oh KJ; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon 34141, Korea.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 26; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Non-alcoholic Fatty Liver Disease*/diagnosis
Non-alcoholic Fatty Liver Disease*/metabolism
Diabetes Mellitus, Type 2/*complications
Liver/*pathology
Obesity/*complications
Adipokines/metabolism ; Carcinoma, Hepatocellular/physiopathology ; Diabetes Mellitus, Type 2/metabolism ; Disease Progression ; Humans ; Liver/metabolism ; Liver Cirrhosis/physiopathology ; Liver Failure ; Liver Neoplasms/physiopathology ; Metabolic Syndrome/physiopathology ; Obesity/metabolism
Czasopismo naukowe
Tytuł :
Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Autorzy :
Baglietto-Vargas D; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain.
Forner S; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Cai L; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Martini AC; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Trujillo-Estrada L; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain.
Swarup V; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.
Nguyen MMT; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Do Huynh K; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Javonillo DI; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Tran KM; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Phan J; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Jiang S; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
Kramár EA; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.
Nuñez-Diaz C; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain.
Balderrama-Gutierrez G; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
Garcia F; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.
Childs J; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.
Rodriguez-Ortiz CJ; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Division of Occupational and Environmental Medicine, Department of Medicine. Center for Occupational and Environmental Health (COEH), University of California, Irvine, CA, USA.
Garcia-Leon JA; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain.
Kitazawa M; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Division of Occupational and Environmental Medicine, Department of Medicine. Center for Occupational and Environmental Health (COEH), University of California, Irvine, CA, USA.
Shahnawaz M; The Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
Matheos DP; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.
Ma X; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
Da Cunha C; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Walls KC; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Ager RR; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Soto C; The Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
Gutierrez A; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain.
Moreno-Gonzalez I; Department of Cell Biology, Genetic and Physiology, Faculty of Sciences, Instituto de Investigacion Biomedica de Malaga-IBIMA, Networking Research Center on Neurodegenerative Diseases (CIBERNED), University of Malaga, Malaga, Spain.; The Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
Mortazavi A; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
Tenner AJ; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, USA.
MacGregor GR; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
Wood M; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA.
Green KN; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA. .; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA. .
LaFerla FM; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA. .; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Apr 23; Vol. 12 (1), pp. 2421. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mutation*
Alzheimer Disease/*physiopathology
Amyloid beta-Peptides/*genetics
Amyloid beta-Protein Precursor/*genetics
Brain/*physiopathology
Neuronal Plasticity/*physiology
Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Animals ; Brain/metabolism ; Female ; Gene Expression Profiling/methods ; Gene Ontology ; Gene Regulatory Networks ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Transgenic ; Neuronal Plasticity/genetics
Czasopismo naukowe
Tytuł :
Dynamics of Cortical Degeneration Over a Decade in Huntington's Disease.
Autorzy :
Johnson EB; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom. Electronic address: .
Ziegler G; Institute of Cognitive Neurology and Dementia Research, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany; German Center for Neurodegenerative Diseases, Magdeburg, Germany. Electronic address: .
Penny W; School of Psychology, University of East Anglia, Norwich, United Kingdom.
Rees G; Wellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
Tabrizi SJ; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom; Dementia Research Institute at University College London, London, United Kingdom.
Scahill RI; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
Gregory S; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
Pokaż więcej
Źródło :
Biological psychiatry [Biol Psychiatry] 2021 Apr 15; Vol. 89 (8), pp. 807-816. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Huntington Disease*/genetics
Huntington Disease*/pathology
Atrophy/pathology ; Bayes Theorem ; Brain/pathology ; Child ; Disease Progression ; Humans ; Magnetic Resonance Imaging
Czasopismo naukowe
Tytuł :
Role of Oxidative DNA Damage and Repair in Atrial Fibrillation and Ischemic Heart Disease.
Autorzy :
Hu L; Human and Animal Physiology, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.
Wang Z; Human and Animal Physiology, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.
Carmone C; Human and Animal Physiology, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.
Keijer J; Human and Animal Physiology, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.
Zhang D; Human and Animal Physiology, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 07; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Repair*
Disease Susceptibility*
Oxidative Stress*
Atrial Fibrillation/*etiology
Myocardial Ischemia/*etiology
Animals ; Atrial Fibrillation/metabolism ; Atrial Fibrillation/therapy ; Biomarkers ; Cell Nucleus/genetics ; Cell Nucleus/metabolism ; Disease Management ; Gene Expression ; Humans ; Models, Biological ; Myocardial Ischemia/metabolism ; Myocardial Ischemia/therapy ; Myocardium/metabolism ; Oxidation-Reduction ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
The OSMR Gene Is Involved in Hirschsprung Associated Enterocolitis Susceptibility through an Altered Downstream Signaling.
Autorzy :
Bachetti T; Laboratory of Developmental Neurobiology, Dipartimento di Scienze della Terra dell'Ambiente e della Vita (DISTAV), Università di Genova, Viale Benedetto XV, 5, 16132 Genova, Italy.; UOSD Laboratorio di Genetica e Genomica delle Malattie Rare, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini, 5, 16148 Genova, Italy.
Rosamilia F; Health Science Department (DISSAL), Biostatistics Unit, Università di Genova, Via Pastore 1, 16132 Genova, Italy.
Bartolucci M; Core Facilities-Clinical Proteomics and Metabolomics, IRCCS, Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147 Genova, Italy.
Santamaria G; UOSD Laboratorio di Genetica e Genomica delle Malattie Rare, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini, 5, 16148 Genova, Italy.
Mosconi M; Fetal and Perinatal Pathology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Via Gerolamo Gaslini 5, 16147 Genova, Italy.
Sartori S; COSR-Center for Omics Sciences, IRCCS Hospital San Raffaele, Dibit2-Basilica, 3A3, Via Olgettina 58, 20132 Milano, Italy.
De Filippo MR; COSR-Center for Omics Sciences, IRCCS Hospital San Raffaele, Dibit2-Basilica, 3A3, Via Olgettina 58, 20132 Milano, Italy.
Di Duca M; Laboratorio di Fisiopatologia dell' Uremia, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147 Genova, Italy.
Obino V; Laboratory of Developmental Neurobiology, Dipartimento di Scienze della Terra dell'Ambiente e della Vita (DISTAV), Università di Genova, Viale Benedetto XV, 5, 16132 Genova, Italy.
Avanzini S; Pediatric Surgery Unit, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147 Genova, Italy.
Mavilio D; Department of Medical Biotechnologies and Translational Medicine, University of Milan, Via Manzoni 113, 20089 Milan, Italy.; Laboratory of Clinical and Experimental Immunology, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano Milan, Italy.
Candiani S; Laboratory of Developmental Neurobiology, Dipartimento di Scienze della Terra dell'Ambiente e della Vita (DISTAV), Università di Genova, Viale Benedetto XV, 5, 16132 Genova, Italy.
Petretto A; Core Facilities-Clinical Proteomics and Metabolomics, IRCCS, Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147 Genova, Italy.
Pini Prato A; Centro Bosio per la Patologia Digestiva Pediatrica, Ospedale Infantile AON SS Antonio e Biagio e Cesare Arrigo, 15121 Alessandria, Italy.
Ceccherini I; UOSD Laboratorio di Genetica e Genomica delle Malattie Rare, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini, 5, 16148 Genova, Italy.
Lantieri F; Health Science Department (DISSAL), Biostatistics Unit, Università di Genova, Via Pastore 1, 16132 Genova, Italy.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 07; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Susceptibility*
Signal Transduction*
Enterocolitis/*etiology
Enterocolitis/*metabolism
Hirschsprung Disease/*complications
Hirschsprung Disease/*genetics
Oncostatin M Receptor beta Subunit/*genetics
Alleles ; Enterocolitis/pathology ; Gene Expression ; Gene Frequency ; Genetic Variation ; Genotype ; Hirschsprung Disease/diagnosis ; Humans ; Models, Molecular ; Oncostatin M Receptor beta Subunit/chemistry ; Oncostatin M Receptor beta Subunit/metabolism ; Protein Conformation ; Proteomics/methods ; Structure-Activity Relationship ; Whole Exome Sequencing ; Whole Genome Sequencing
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies