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Wyszukujesz frazę ""DISEASE progression"" wg kryterium: Temat


Tytuł:
Role of Disease Progression Models in Drug Development.
Autorzy:
Barrett JS; Rare Disease Cures Accelerator Data Analytics Platform, Critical Path Institute, Tuscon, AZ, 85718, USA. .
Nicholas T; Global Product Development, Pfizer Inc, 445 Eastern Point Rd, Groton, CT, 06340, USA.
Azer K; Axcella Therapeutics, 840 Memorial Drive, Cambridge, MA, 02139, USA.
Corrigan BW; Global Product Development, Pfizer Inc, 445 Eastern Point Rd, Groton, CT, 06340, USA.
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Źródło:
Pharmaceutical research [Pharm Res] 2022 Aug; Vol. 39 (8), pp. 1803-1815. Date of Electronic Publication: 2022 Apr 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Disease Progression*
Drug Development*
Clinical Trials as Topic ; Humans ; Research Design
Czasopismo naukowe
Tytuł:
Application of the Clustering Technique to Multiple Nutritional Factors Related to Inflammation and Disease Progression in Patients with Inflammatory Bowel Disease.
Autorzy:
Dąbek-Drobny A; Unit of Clinical Dietetics, Department of Gastroenterology and Hepatology, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Kaczmarczyk O; Department of Gastroenterology and Hepatology, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Piątek-Guziewicz A; Department of Gastroenterology and Hepatology, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Woźniakiewicz M; Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University, 31-008 Krakow, Poland.
Paśko P; Department of Food Chemistry and Nutrition, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Dobrowolska-Iwanek J; Department of Food Chemistry and Nutrition, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Woźniakiewicz A; Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University, 31-008 Krakow, Poland.
Targosz A; Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Ptak-Belowska A; Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Zagrodzki P; Department of Food Chemistry and Nutrition, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Zwolińska-Wcisło M; Unit of Clinical Dietetics, Department of Gastroenterology and Hepatology, Jagiellonian University Medical College, 31-008 Krakow, Poland.; Department of Gastroenterology and Hepatology, Jagiellonian University Medical College, 31-008 Krakow, Poland.
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Źródło:
Nutrients [Nutrients] 2022 Sep 23; Vol. 14 (19). Date of Electronic Publication: 2022 Sep 23.
Typ publikacji:
Journal Article
MeSH Terms:
Disease Progression*
Inflammatory Bowel Diseases*/metabolism
Anti-Inflammatory Agents ; C-Reactive Protein/metabolism ; Cluster Analysis ; Cytokines/metabolism ; Fatty Acids, Volatile/metabolism ; Humans ; Inflammation ; Interleukin-10 ; Interleukin-17 ; Interleukin-6 ; Interleukins ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł:
Does early disease progression predict survival after first line-treatment of Waldenström macroglobulinemia?
Autorzy:
Labreuche J; Universite de Lille, CHU Lille, ULR 2694-METRICS: évaluation des technologies de santé et des pratiques médicales, Lille, France.; Departement de Biostatistique, CHU de Lille, Lille, France.
Assouan D; Service d'Hematologie Clinique et Therapie Cellulaire, Centre Hospitalier Universitaire d'Amiens-Picardie, Amiens, France.
Durot E; Service d'Hématologie Clinique, Hôpital Robert Debré, Centre Hospitalier Universitaire de Reims, Reims, France.
Tomowiak C; Service d'Oncologie Hématologie et Thérapie cellulaire, CHU de Poitiers, Poitiers, France.
Roos-Weil D; Hôpital Pitié Salpêtrière APHP GRC-11 UPMC, Paris, France.
Toussaint E; Departement d'Hematologie, CHU de Strasbourg, Strasbourg, France.
Bijou F; Departement d'Hematologie, Institut Bergonié, Bordeaux, France.
Lemal R; Service d'Hematologie Clinique Adultes de Thérapie Cellulaire, Hôpital Estaing, Université d'Auvergne EA7283, Inserm CIC-501, CHU Clermont-Ferrand, Clermont Ferrand, France.
Brion A; Departement d'Hematologie, CHRU de Besançon, Besançon, France.
Laribi K; Departement d'Hematologie, Centre Hospitalier du Mans, Le Mans, France.
Ysebaert L; Service d'Hématologie IUC Toulouse-Oncopole Toulouse, Toulouse, France.
Duhamel A; Universite de Lille, CHU Lille, ULR 2694-METRICS: évaluation des technologies de santé et des pratiques médicales, Lille, France.; Departement de Biostatistique, CHU de Lille, Lille, France.
Morel P; Universite de Lille, CHU Lille, ULR 2694-METRICS: évaluation des technologies de santé et des pratiques médicales, Lille, France.; Service d'Hematologie Clinique et Therapie Cellulaire, Centre Hospitalier Universitaire d'Amiens-Picardie, Amiens, France.; Service d'Hematologie Clinique, Centre Hospitalier Schaffner, Lens, France.
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Corporate Authors:
French Innovative Leukaemia Organisation (FILO) Chronic Lymphocytic Leukaemia group
Źródło:
Hematological oncology [Hematol Oncol] 2022 Aug; Vol. 40 (3), pp. 400-408. Date of Electronic Publication: 2022 May 01.
Typ publikacji:
Journal Article
MeSH Terms:
Disease Progression*
Waldenstrom Macroglobulinemia*/pathology
Waldenstrom Macroglobulinemia*/therapy
Humans ; Prognosis ; Progression-Free Survival
Czasopismo naukowe
Tytuł:
Ordered and deterministic cancer genome evolution after p53 loss.
Autorzy:
Baslan T; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Morris JP 4th; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Zhao Z; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Pathology, Molecular and Cell-based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Reyes J; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
Ho YJ; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Tsanov KM; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Bermeo J; Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Tian S; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Zhang S; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Askan G; Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Yavas A; Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lecomte N; Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Erakky A; Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Varghese AM; Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Zhang A; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Kendall J; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Ghiban E; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Chorbadjiev L; Technical School of Electronic Systems, Technical University of Sofia, Sofia, Bulgaria.
Wu J; Phillips Research North America, Oncology Informatics and Genomics, Cambridge, MA, USA.
Dimitrova N; Phillips Research North America, Oncology Informatics and Genomics, Cambridge, MA, USA.
Chadalavada K; Molecular Cytogenetics Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nanjangud GJ; Molecular Cytogenetics Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Bandlamudi C; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Gong Y; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Donoghue MTA; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Socci ND; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Krasnitz A; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Notta F; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Leach SD; Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Dartmouth Cancer Center, Hanover, NH, USA.
Iacobuzio-Donahue CA; Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lowe SW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. .; Howard Hughes Medical Institute, Chevy Chase, MD, USA. .
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Źródło:
Nature [Nature] 2022 Aug; Vol. 608 (7924), pp. 795-802. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinogenesis*/genetics
Carcinogenesis*/pathology
Disease Progression*
Genes, p53*/genetics
Genome*/genetics
Loss of Heterozygosity*
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/pathology
Tumor Suppressor Protein p53*/genetics
Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Animals ; Carcinoma, Pancreatic Ductal/genetics ; Carcinoma, Pancreatic Ductal/pathology ; Evolution, Molecular ; Gene Deletion ; Mice ; Models, Genetic
Czasopismo naukowe
Tytuł:
Ocular manifestations in Kindler syndrome.
Autorzy:
Maharana PK; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Sahay P; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Mandal S; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Nagpal R; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Sharma N; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
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Źródło:
Indian journal of ophthalmology [Indian J Ophthalmol] 2022 Jul; Vol. 70 (7), pp. 2585-2587.
Typ publikacji:
Case Reports
MeSH Terms:
Blister*
Disease Progression*
Eye Diseases*/etiology
Periodontal Diseases*
Photosensitivity Disorders*/complications
Photosensitivity Disorders*/diagnosis
Adult ; Child ; Epidermolysis Bullosa ; Eye ; Face ; Female ; Humans ; Male
SCR Disease Name:
Poikiloderma of Kindler
Raport
Tytuł:
Baseline serum Krebs von den Lungen-6 as a biomarker for the disease progression in idiopathic pulmonary fibrosis.
Autorzy:
Chung C; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Kim J; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Cho HS; University of Ulsan College of Medicine, Seoul, Republic of Korea.
Kim HC; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2022 May 20; Vol. 12 (1), pp. 8564. Date of Electronic Publication: 2022 May 20.
Typ publikacji:
Journal Article
MeSH Terms:
Disease Progression*
Idiopathic Pulmonary Fibrosis*/diagnosis
Idiopathic Pulmonary Fibrosis*/metabolism
Mucin-1*/metabolism
Biomarkers ; Humans ; Lung/pathology ; Vital Capacity
Czasopismo naukowe
Tytuł:
The Suppressor of Cytokine Signalling family of proteins and their potential impact on COVID-19 disease progression.
Autorzy:
Low ZY; School of Science, Monash University, Bandar Sunway, Selangor, Malaysia.
Wen Yip AJ; School of Science, Monash University, Bandar Sunway, Selangor, Malaysia.
Chow VTK; Infectious Diseases Translational Research Program, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Lal SK; School of Science, Monash University, Bandar Sunway, Selangor, Malaysia.; Tropical Medicine and Biology Platform, Monash University, Bandar Sunway, Selangor, Malaysia.
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Źródło:
Reviews in medical virology [Rev Med Virol] 2022 May; Vol. 32 (3), pp. e2300. Date of Electronic Publication: 2021 Sep 21.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*
Disease Progression*
Suppressor of Cytokine Signaling Proteins*/genetics
Suppressor of Cytokine Signaling Proteins*/metabolism
Cytokines/metabolism ; Humans ; SARS-CoV-2 ; Suppressor of Cytokine Signaling 3 Protein/genetics ; Suppressor of Cytokine Signaling 3 Protein/metabolism
Czasopismo naukowe
Tytuł:
Th17 cells and their related cytokines: vital players in progression of malignant pleural effusion.
Autorzy:
Niu Y; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue 1277, Wuhan, Hubei, China.
Zhou Q; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue 1277, Wuhan, Hubei, China. .
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Źródło:
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Mar 17; Vol. 79 (4), pp. 194. Date of Electronic Publication: 2022 Mar 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Disease Progression*
Cytokines/*metabolism
Pleural Effusion, Malignant/*immunology
Pleural Effusion, Malignant/*pathology
Th17 Cells/*immunology
Animals ; Cell Communication ; Humans ; Models, Biological
Czasopismo naukowe
Tytuł:
Augmentation in patients with restless legs syndrome receiving pramipexole therapy: a retrospective study in a single center from China.
Autorzy:
Wang T; Department of Pharmacy, Xiasha Campus, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 368 Rd Xiasha, Zhejiang Province, 310016, Hangzhou, China.; Institute of Pharmacology and Toxicology, College of Pharmaceutical Science, Zhejiang University, No. 866 Rd Yuhangtang, Zhejiang Province, 310058, Hangzhou, China.; Center for Sleep Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3 Rd East Qingchun, Zhejiang Province, 310016, Hangzhou, China.
Ying M; Department of Pharmacy, Xiasha Campus, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 368 Rd Xiasha, Zhejiang Province, 310016, Hangzhou, China.
Zhao R; Department of Pharmacy, Xiasha Campus, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 368 Rd Xiasha, Zhejiang Province, 310016, Hangzhou, China.
Zhu D; Institute of Pharmacology and Toxicology, College of Pharmaceutical Science, Zhejiang University, No. 866 Rd Yuhangtang, Zhejiang Province, 310058, Hangzhou, China. .
Zhang L; Center for Sleep Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3 Rd East Qingchun, Zhejiang Province, 310016, Hangzhou, China. .; Department of Neurology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3 Rd East Qingchun, Zhejiang Province, 310016, Hangzhou, China. .
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Źródło:
Sleep & breathing = Schlaf & Atmung [Sleep Breath] 2022 Mar; Vol. 26 (1), pp. 373-380. Date of Electronic Publication: 2021 Apr 16.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Disease Progression*
Dopamine Agonists/*adverse effects
Pramipexole/*adverse effects
Restless Legs Syndrome/*drug therapy
Adult ; Aged ; China ; Dopamine Agonists/therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Pramipexole/therapeutic use ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Significance of a PTEN Mutational Status-Associated Gene Signature in the Progression and Prognosis of Endometrial Carcinoma.
Autorzy:
Wu Y; Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Wang J; Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Ge L; Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Hu Q; Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
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Źródło:
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2022 Feb 23; Vol. 2022, pp. 5130648. Date of Electronic Publication: 2022 Feb 23 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Disease Progression*
Gene Expression Regulation, Neoplastic*
Mutation*
Endometrial Neoplasms/*genetics
Endometrial Neoplasms/*mortality
PTEN Phosphohydrolase/*genetics
Transcriptome/*genetics
Adult ; Biomarkers, Tumor/genetics ; Female ; Gene Expression Profiling/methods ; Humans ; Kaplan-Meier Estimate ; Middle Aged ; Nomograms ; Polymorphism, Single Nucleotide ; Prognosis ; ROC Curve ; Survival Rate
Czasopismo naukowe
Tytuł:
Association of B-type natriuretic peptide with rapid progression in patients with aortic stenosis.
Autorzy:
Han K; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, 100029 Beijing, China.; The Key Laboratory of Remodeling-related Cardiovascular Disease, Ministry of Education, 100029 Beijing, China.
Shi D; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, 100029 Beijing, China.; The Key Laboratory of Remodeling-related Cardiovascular Disease, Ministry of Education, 100029 Beijing, China.
Yang L; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, 100029 Beijing, China.; The Key Laboratory of Remodeling-related Cardiovascular Disease, Ministry of Education, 100029 Beijing, China.
Xie M; Beijing Institute of Heart, Lung and Blood Vessel Diseases, 100029 Beijing, China.; Department of Echocardiogram, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.
Wang Z; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, 100029 Beijing, China.; The Key Laboratory of Remodeling-related Cardiovascular Disease, Ministry of Education, 100029 Beijing, China.
Gao F; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, 100029 Beijing, China.; The Key Laboratory of Remodeling-related Cardiovascular Disease, Ministry of Education, 100029 Beijing, China.
Ma X; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, 100029 Beijing, China.; The Key Laboratory of Remodeling-related Cardiovascular Disease, Ministry of Education, 100029 Beijing, China.
Zhou Y; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, 100029 Beijing, China.; The Key Laboratory of Remodeling-related Cardiovascular Disease, Ministry of Education, 100029 Beijing, China.
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Źródło:
Reviews in cardiovascular medicine [Rev Cardiovasc Med] 2022 Feb 22; Vol. 23 (2), pp. 75.
Typ publikacji:
Journal Article
MeSH Terms:
Aortic Valve Stenosis*/blood
Aortic Valve Stenosis*/diagnostic imaging
Aortic Valve Stenosis*/physiopathology
Disease Progression*
Natriuretic Peptide, Brain*/blood
Biomarkers/blood ; Echocardiography ; Female ; Humans ; Male ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Efficacy and Safety of Masitinib in Progressive Forms of Multiple Sclerosis: A Randomized, Phase 3, Clinical Trial.
Autorzy:
Vermersch P; From the Univ. Lille (P.V.), UMR Inserm U1172, CHU Lille, FHU Precise, France; Neurology Department (L.B.-R.), Hospital Arnau de Vilanova de Lleida, Spain; Mellen Center for Multiple Sclerosis (R.J.F.), Neurological Institute, Cleveland Clinic, OH; Experimental and Clinical Research Center and NeuroCure Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Neurology Department (L.R.-T.), Dr Josep Trueta University Hospital, Girona; Neurodegeneration and Neuroinflammation Research Group (L.R.-T.), IDIBGI, Salt; Medical Science Department (L.R.-T.), University of Girona, Spain; Neurology Department (M.S.), Jena University Hospital, Germany; AB Science (A.M., C.M., O.H.), Paris, France; Imagine Institute (O.H.), INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; and MA LEK AM Maciejowscy SC Centrum Terapii SM (M.M.), Katowice, Poland. .
Brieva-Ruiz L; From the Univ. Lille (P.V.), UMR Inserm U1172, CHU Lille, FHU Precise, France; Neurology Department (L.B.-R.), Hospital Arnau de Vilanova de Lleida, Spain; Mellen Center for Multiple Sclerosis (R.J.F.), Neurological Institute, Cleveland Clinic, OH; Experimental and Clinical Research Center and NeuroCure Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Neurology Department (L.R.-T.), Dr Josep Trueta University Hospital, Girona; Neurodegeneration and Neuroinflammation Research Group (L.R.-T.), IDIBGI, Salt; Medical Science Department (L.R.-T.), University of Girona, Spain; Neurology Department (M.S.), Jena University Hospital, Germany; AB Science (A.M., C.M., O.H.), Paris, France; Imagine Institute (O.H.), INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; and MA LEK AM Maciejowscy SC Centrum Terapii SM (M.M.), Katowice, Poland.
Fox RJ; From the Univ. Lille (P.V.), UMR Inserm U1172, CHU Lille, FHU Precise, France; Neurology Department (L.B.-R.), Hospital Arnau de Vilanova de Lleida, Spain; Mellen Center for Multiple Sclerosis (R.J.F.), Neurological Institute, Cleveland Clinic, OH; Experimental and Clinical Research Center and NeuroCure Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Neurology Department (L.R.-T.), Dr Josep Trueta University Hospital, Girona; Neurodegeneration and Neuroinflammation Research Group (L.R.-T.), IDIBGI, Salt; Medical Science Department (L.R.-T.), University of Girona, Spain; Neurology Department (M.S.), Jena University Hospital, Germany; AB Science (A.M., C.M., O.H.), Paris, France; Imagine Institute (O.H.), INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; and MA LEK AM Maciejowscy SC Centrum Terapii SM (M.M.), Katowice, Poland.
Paul F; From the Univ. Lille (P.V.), UMR Inserm U1172, CHU Lille, FHU Precise, France; Neurology Department (L.B.-R.), Hospital Arnau de Vilanova de Lleida, Spain; Mellen Center for Multiple Sclerosis (R.J.F.), Neurological Institute, Cleveland Clinic, OH; Experimental and Clinical Research Center and NeuroCure Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Neurology Department (L.R.-T.), Dr Josep Trueta University Hospital, Girona; Neurodegeneration and Neuroinflammation Research Group (L.R.-T.), IDIBGI, Salt; Medical Science Department (L.R.-T.), University of Girona, Spain; Neurology Department (M.S.), Jena University Hospital, Germany; AB Science (A.M., C.M., O.H.), Paris, France; Imagine Institute (O.H.), INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; and MA LEK AM Maciejowscy SC Centrum Terapii SM (M.M.), Katowice, Poland.
Ramio-Torrenta L; From the Univ. Lille (P.V.), UMR Inserm U1172, CHU Lille, FHU Precise, France; Neurology Department (L.B.-R.), Hospital Arnau de Vilanova de Lleida, Spain; Mellen Center for Multiple Sclerosis (R.J.F.), Neurological Institute, Cleveland Clinic, OH; Experimental and Clinical Research Center and NeuroCure Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Neurology Department (L.R.-T.), Dr Josep Trueta University Hospital, Girona; Neurodegeneration and Neuroinflammation Research Group (L.R.-T.), IDIBGI, Salt; Medical Science Department (L.R.-T.), University of Girona, Spain; Neurology Department (M.S.), Jena University Hospital, Germany; AB Science (A.M., C.M., O.H.), Paris, France; Imagine Institute (O.H.), INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; and MA LEK AM Maciejowscy SC Centrum Terapii SM (M.M.), Katowice, Poland.
Schwab M; From the Univ. Lille (P.V.), UMR Inserm U1172, CHU Lille, FHU Precise, France; Neurology Department (L.B.-R.), Hospital Arnau de Vilanova de Lleida, Spain; Mellen Center for Multiple Sclerosis (R.J.F.), Neurological Institute, Cleveland Clinic, OH; Experimental and Clinical Research Center and NeuroCure Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Neurology Department (L.R.-T.), Dr Josep Trueta University Hospital, Girona; Neurodegeneration and Neuroinflammation Research Group (L.R.-T.), IDIBGI, Salt; Medical Science Department (L.R.-T.), University of Girona, Spain; Neurology Department (M.S.), Jena University Hospital, Germany; AB Science (A.M., C.M., O.H.), Paris, France; Imagine Institute (O.H.), INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; and MA LEK AM Maciejowscy SC Centrum Terapii SM (M.M.), Katowice, Poland.
Moussy A; From the Univ. Lille (P.V.), UMR Inserm U1172, CHU Lille, FHU Precise, France; Neurology Department (L.B.-R.), Hospital Arnau de Vilanova de Lleida, Spain; Mellen Center for Multiple Sclerosis (R.J.F.), Neurological Institute, Cleveland Clinic, OH; Experimental and Clinical Research Center and NeuroCure Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Neurology Department (L.R.-T.), Dr Josep Trueta University Hospital, Girona; Neurodegeneration and Neuroinflammation Research Group (L.R.-T.), IDIBGI, Salt; Medical Science Department (L.R.-T.), University of Girona, Spain; Neurology Department (M.S.), Jena University Hospital, Germany; AB Science (A.M., C.M., O.H.), Paris, France; Imagine Institute (O.H.), INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; and MA LEK AM Maciejowscy SC Centrum Terapii SM (M.M.), Katowice, Poland.
Mansfield C; From the Univ. Lille (P.V.), UMR Inserm U1172, CHU Lille, FHU Precise, France; Neurology Department (L.B.-R.), Hospital Arnau de Vilanova de Lleida, Spain; Mellen Center for Multiple Sclerosis (R.J.F.), Neurological Institute, Cleveland Clinic, OH; Experimental and Clinical Research Center and NeuroCure Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Neurology Department (L.R.-T.), Dr Josep Trueta University Hospital, Girona; Neurodegeneration and Neuroinflammation Research Group (L.R.-T.), IDIBGI, Salt; Medical Science Department (L.R.-T.), University of Girona, Spain; Neurology Department (M.S.), Jena University Hospital, Germany; AB Science (A.M., C.M., O.H.), Paris, France; Imagine Institute (O.H.), INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; and MA LEK AM Maciejowscy SC Centrum Terapii SM (M.M.), Katowice, Poland.
Hermine O; From the Univ. Lille (P.V.), UMR Inserm U1172, CHU Lille, FHU Precise, France; Neurology Department (L.B.-R.), Hospital Arnau de Vilanova de Lleida, Spain; Mellen Center for Multiple Sclerosis (R.J.F.), Neurological Institute, Cleveland Clinic, OH; Experimental and Clinical Research Center and NeuroCure Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Neurology Department (L.R.-T.), Dr Josep Trueta University Hospital, Girona; Neurodegeneration and Neuroinflammation Research Group (L.R.-T.), IDIBGI, Salt; Medical Science Department (L.R.-T.), University of Girona, Spain; Neurology Department (M.S.), Jena University Hospital, Germany; AB Science (A.M., C.M., O.H.), Paris, France; Imagine Institute (O.H.), INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; and MA LEK AM Maciejowscy SC Centrum Terapii SM (M.M.), Katowice, Poland.
Maciejowski M; From the Univ. Lille (P.V.), UMR Inserm U1172, CHU Lille, FHU Precise, France; Neurology Department (L.B.-R.), Hospital Arnau de Vilanova de Lleida, Spain; Mellen Center for Multiple Sclerosis (R.J.F.), Neurological Institute, Cleveland Clinic, OH; Experimental and Clinical Research Center and NeuroCure Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Neurology Department (L.R.-T.), Dr Josep Trueta University Hospital, Girona; Neurodegeneration and Neuroinflammation Research Group (L.R.-T.), IDIBGI, Salt; Medical Science Department (L.R.-T.), University of Girona, Spain; Neurology Department (M.S.), Jena University Hospital, Germany; AB Science (A.M., C.M., O.H.), Paris, France; Imagine Institute (O.H.), INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; and MA LEK AM Maciejowscy SC Centrum Terapii SM (M.M.), Katowice, Poland.
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Corporate Authors:
AB07002 Study Group
Źródło:
Neurology(R) neuroimmunology & neuroinflammation [Neurol Neuroimmunol Neuroinflamm] 2022 Feb 21; Vol. 9 (3). Date of Electronic Publication: 2022 Feb 21 (Print Publication: 2022).
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Progression*
Benzamides/*pharmacology
Multiple Sclerosis, Chronic Progressive/*drug therapy
Piperidines/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Pyridines/*pharmacology
Thiazoles/*pharmacology
Adolescent ; Adult ; Benzamides/administration & dosage ; Benzamides/adverse effects ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Outcome Assessment, Health Care ; Piperidines/administration & dosage ; Piperidines/adverse effects ; Protein Kinase Inhibitors/administration & dosage ; Protein Kinase Inhibitors/adverse effects ; Pyridines/administration & dosage ; Pyridines/adverse effects ; Thiazoles/administration & dosage ; Thiazoles/adverse effects ; Young Adult
Czasopismo naukowe
Tytuł:
Pre-infection plasma cytokines and chemokines as predictors of HIV disease progression.
Autorzy:
Ngcobo S; Centre for the AIDS Programme of Research in South Africa (CAPRISA), 719 Umbilo Road, Durban, South Africa.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa.
Molatlhegi RP; Centre for the AIDS Programme of Research in South Africa (CAPRISA), 719 Umbilo Road, Durban, South Africa.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa.
Osman F; Centre for the AIDS Programme of Research in South Africa (CAPRISA), 719 Umbilo Road, Durban, South Africa.
Ngcapu S; Centre for the AIDS Programme of Research in South Africa (CAPRISA), 719 Umbilo Road, Durban, South Africa.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa.
Samsunder N; Centre for the AIDS Programme of Research in South Africa (CAPRISA), 719 Umbilo Road, Durban, South Africa.
Garrett NJ; Centre for the AIDS Programme of Research in South Africa (CAPRISA), 719 Umbilo Road, Durban, South Africa.; Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Abdool Karim SS; Centre for the AIDS Programme of Research in South Africa (CAPRISA), 719 Umbilo Road, Durban, South Africa.; Department of Epidemiology, Columbia University, New York, NY, USA.
Abdool Karim Q; Centre for the AIDS Programme of Research in South Africa (CAPRISA), 719 Umbilo Road, Durban, South Africa.; Department of Epidemiology, Columbia University, New York, NY, USA.
McKinnon LR; Centre for the AIDS Programme of Research in South Africa (CAPRISA), 719 Umbilo Road, Durban, South Africa.; Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada.; Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya.
Sivro A; Centre for the AIDS Programme of Research in South Africa (CAPRISA), 719 Umbilo Road, Durban, South Africa. .; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 14; Vol. 12 (1), pp. 2437. Date of Electronic Publication: 2022 Feb 14.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Progression*
Anti-HIV Agents/*therapeutic use
Chemokines/*blood
HIV Infections/*blood
HIV Infections/*prevention & control
HIV-1/*immunology
Tenofovir/*therapeutic use
Adolescent ; Adult ; Biomarkers/blood ; CD4-CD8 Ratio ; Cohort Studies ; Double-Blind Method ; Female ; HIV Infections/epidemiology ; HIV Infections/immunology ; HIV Seropositivity ; Humans ; Immunity ; Prognosis ; South Africa/epidemiology ; Treatment Outcome ; Viral Load ; Young Adult
Czasopismo naukowe
Tytuł:
Nickel particles are present in Crohn's disease tissue and exacerbate intestinal inflammation in IBD susceptible mice.
Autorzy:
Matsuda H; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Nibe-Shirakihara Y; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Japan.
Tamura A; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Aonuma E; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Arakawa S; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Japan.
Otsubo K; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Nemoto Y; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Nagaishi T; Department of Advanced Therapeutics for G.I. Diseases, Tokyo Medical and Dental University, Tokyo, Japan.
Tsuchiya K; Department of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Shimizu S; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Japan.
Ma A; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Watanabe M; Advanced Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Uo M; Department of Advanced Biomaterials, Tokyo Medical and Dental University, Tokyo, Japan.
Okamoto R; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Oshima S; Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Feb 12; Vol. 592, pp. 74-80. Date of Electronic Publication: 2022 Jan 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Progression*
Crohn Disease/*pathology
Inflammation/*pathology
Intestines/*pathology
Nickel/*toxicity
Animals ; Autophagy/drug effects ; Autophagy-Related Protein 5/metabolism ; Dextran Sulfate ; Disease Susceptibility ; Humans ; Macrophages/drug effects ; Macrophages/pathology ; Macrophages/ultrastructure ; Mice, Inbred C57BL ; THP-1 Cells ; Tumor Necrosis Factor alpha-Induced Protein 3/metabolism
Czasopismo naukowe
Tytuł:
Association of ischemic stroke onset time with presenting severity, acute progression, and long-term outcome: A cohort study.
Autorzy:
Ryu WS; Department of Neurology, Dongguk University Ilsan Hospital, Goyang, Korea.; National Priority Research Center for Stroke, Goyang, Korea.
Hong KS; Department of Neurology, Inje University Ilsan Paik Hospital, Goyang, Korea.
Jeong SW; Department of Neurology, Dongguk University Ilsan Hospital, Goyang, Korea.
Park JE; Department of Neurology, Dongguk University Ilsan Hospital, Goyang, Korea.
Kim BJ; Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.
Kim JT; Department of Neurology, Chonnam National University Hospital, Gwangju, Korea.
Lee KB; Department of Neurology, Soonchunhyang University Hospital, Seoul, Korea.
Park TH; Department of Neurology, Seoul Medical Center, Seoul, Korea.
Park SS; Department of Neurology, Seoul Medical Center, Seoul, Korea.
Park JM; Department of Neurology, Uijeongbu Eulji Medical Center, Uijeongbu, Korea.
Kang K; Department of Neurology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea.
Cho YJ; Department of Neurology, Inje University Ilsan Paik Hospital, Goyang, Korea.
Park HK; Department of Neurology, Inje University Ilsan Paik Hospital, Goyang, Korea.
Lee BC; Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea.
Yu KH; Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea.
Oh MS; Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea.
Lee SJ; Department of Neurology, Eulji University Hospital, Daejeon, Korea.
Kim JG; Department of Neurology, Eulji University Hospital, Daejeon, Korea.
Cha JK; Department of Neurology, Dong-A University Hospital, Busan, Korea.
Kim DH; Department of Neurology, Dong-A University Hospital, Busan, Korea.
Lee J; Department of Neurology, Yeungnam University Hospital, Daegu, Korea.
Han MK; Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.
Park MS; Department of Neurology, Chonnam National University Hospital, Gwangju, Korea.
Choi KH; Department of Neurology, Chonnam National University Hospital, Gwangju, Korea.
Lee J; Department of Biostatistics, Korea University, Seoul, Korea.
Saver JL; Comprehensive Stroke Center, Department of Neurology, University of California, Los Angeles, California, United States of America.; Consortium International pour la Recherche Circadienne sur l'AVC (CIRCA).
Lo EH; Consortium International pour la Recherche Circadienne sur l'AVC (CIRCA).; Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
Bae HJ; Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.; Consortium International pour la Recherche Circadienne sur l'AVC (CIRCA).
Kim DE; Department of Neurology, Dongguk University Ilsan Hospital, Goyang, Korea.; National Priority Research Center for Stroke, Goyang, Korea.; Consortium International pour la Recherche Circadienne sur l'AVC (CIRCA).
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Źródło:
PLoS medicine [PLoS Med] 2022 Feb 04; Vol. 19 (2), pp. e1003910. Date of Electronic Publication: 2022 Feb 04 (Print Publication: 2022).
Typ publikacji:
Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Progression*
Patient Acuity*
Circadian Rhythm/*physiology
Ischemic Stroke/*epidemiology
Ischemic Stroke/*physiopathology
Recovery of Function/*physiology
Aged ; Aged, 80 and over ; Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Ischemic Stroke/diagnosis ; Male ; Middle Aged ; Prospective Studies ; Republic of Korea/epidemiology ; Risk Factors ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Slowly Expanding Lesions Predict 9-Year Multiple Sclerosis Disease Progression.
Autorzy:
Preziosa P; From the Neuroimaging Research Unit (P.P., E.P., A.M., M.F., M.A.R.), Division of Neuroscience; Neurology Unit (P.P., L.M., M.R., M.F., M.A.R.); Neurorehabilitation Unit (M.F.); Neurophysiology Service (M.F.), IRCCS San Raffaele Scientific Institute; and Vita-Salute San Raffaele University (M.F., M.A.R.); Milan, Italy.
Pagani E; From the Neuroimaging Research Unit (P.P., E.P., A.M., M.F., M.A.R.), Division of Neuroscience; Neurology Unit (P.P., L.M., M.R., M.F., M.A.R.); Neurorehabilitation Unit (M.F.); Neurophysiology Service (M.F.), IRCCS San Raffaele Scientific Institute; and Vita-Salute San Raffaele University (M.F., M.A.R.); Milan, Italy.
Meani A; From the Neuroimaging Research Unit (P.P., E.P., A.M., M.F., M.A.R.), Division of Neuroscience; Neurology Unit (P.P., L.M., M.R., M.F., M.A.R.); Neurorehabilitation Unit (M.F.); Neurophysiology Service (M.F.), IRCCS San Raffaele Scientific Institute; and Vita-Salute San Raffaele University (M.F., M.A.R.); Milan, Italy.
Moiola L; From the Neuroimaging Research Unit (P.P., E.P., A.M., M.F., M.A.R.), Division of Neuroscience; Neurology Unit (P.P., L.M., M.R., M.F., M.A.R.); Neurorehabilitation Unit (M.F.); Neurophysiology Service (M.F.), IRCCS San Raffaele Scientific Institute; and Vita-Salute San Raffaele University (M.F., M.A.R.); Milan, Italy.
Rodegher M; From the Neuroimaging Research Unit (P.P., E.P., A.M., M.F., M.A.R.), Division of Neuroscience; Neurology Unit (P.P., L.M., M.R., M.F., M.A.R.); Neurorehabilitation Unit (M.F.); Neurophysiology Service (M.F.), IRCCS San Raffaele Scientific Institute; and Vita-Salute San Raffaele University (M.F., M.A.R.); Milan, Italy.
Filippi M; From the Neuroimaging Research Unit (P.P., E.P., A.M., M.F., M.A.R.), Division of Neuroscience; Neurology Unit (P.P., L.M., M.R., M.F., M.A.R.); Neurorehabilitation Unit (M.F.); Neurophysiology Service (M.F.), IRCCS San Raffaele Scientific Institute; and Vita-Salute San Raffaele University (M.F., M.A.R.); Milan, Italy.
Rocca MA; From the Neuroimaging Research Unit (P.P., E.P., A.M., M.F., M.A.R.), Division of Neuroscience; Neurology Unit (P.P., L.M., M.R., M.F., M.A.R.); Neurorehabilitation Unit (M.F.); Neurophysiology Service (M.F.), IRCCS San Raffaele Scientific Institute; and Vita-Salute San Raffaele University (M.F., M.A.R.); Milan, Italy. .
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Źródło:
Neurology(R) neuroimmunology & neuroinflammation [Neurol Neuroimmunol Neuroinflamm] 2022 Feb 01; Vol. 9 (2). Date of Electronic Publication: 2022 Feb 01 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Progression*
Multiple Sclerosis, Relapsing-Remitting*/diagnostic imaging
Multiple Sclerosis, Relapsing-Remitting*/drug therapy
Multiple Sclerosis, Relapsing-Remitting*/pathology
Multiple Sclerosis, Relapsing-Remitting*/physiopathology
Immunologic Factors/*pharmacology
Adult ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Prognosis
Czasopismo naukowe
Tytuł:
Radiological progression of extremity soft tissue sarcoma following pre-operative radiotherapy predicts for poor survival.
Autorzy:
Isaac C; University of Toronto Musculoskeletal Oncology Unit, Mount Sinai Hospital, Toronto, Canada.
Kavanagh J; Department of Medical Imaging, Mount Sinai Hospital and Princess Margaret Cancer Center, University of Toronto, Toronto, Canada.
Griffin AM; University of Toronto Musculoskeletal Oncology Unit, Mount Sinai Hospital, Toronto, Canada.
Dickie CI; Department of Radiation Oncology, Princess Margaret Cancer Centre and University of Toronto, Toronto, Canada.
Mohankumar R; Department of Medical Imaging, Mount Sinai Hospital and Princess Margaret Cancer Center, University of Toronto, Toronto, Canada.
Chung PW; Department of Radiation Oncology, Princess Margaret Cancer Centre and University of Toronto, Toronto, Canada.
Catton CN; Department of Radiation Oncology, Princess Margaret Cancer Centre and University of Toronto, Toronto, Canada.
Shultz D; Department of Radiation Oncology, Princess Margaret Cancer Centre and University of Toronto, Toronto, Canada.
Ferguson PC; University of Toronto Musculoskeletal Oncology Unit, Mount Sinai Hospital, Toronto, Canada.; Department of Surgical Oncology, Princess Margaret Cancer Center, Toronto, Canada.; Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, Toronto, Canada.
Wunder JS; University of Toronto Musculoskeletal Oncology Unit, Mount Sinai Hospital, Toronto, Canada.; Department of Surgical Oncology, Princess Margaret Cancer Center, Toronto, Canada.; Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, Toronto, Canada.
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Źródło:
The British journal of radiology [Br J Radiol] 2022 Feb 01; Vol. 95 (1130), pp. 20210936. Date of Electronic Publication: 2021 Dec 03.
Typ publikacji:
Journal Article
MeSH Terms:
Disease Progression*
Extremities*
Tumor Burden*/radiation effects
Hemangiosarcoma/*diagnostic imaging
Liposarcoma, Myxoid/*diagnostic imaging
Magnetic Resonance Imaging/*methods
Sarcoma/*diagnostic imaging
Databases, Factual ; Disease-Free Survival ; Female ; Hemangiosarcoma/pathology ; Hemangiosarcoma/radiotherapy ; Hemangiosarcoma/surgery ; Humans ; Liposarcoma, Myxoid/pathology ; Liposarcoma, Myxoid/radiotherapy ; Liposarcoma, Myxoid/surgery ; Male ; Middle Aged ; Preoperative Care ; Retrospective Studies ; Sarcoma/pathology ; Sarcoma/radiotherapy ; Sarcoma/surgery
Czasopismo naukowe
Tytuł:
"Real-world" eligibility for aducanumab depends on clinical setting and patients' journey.
Autorzy:
Padovani A; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Neurology Unit, Department of Neurological and Vision Sciences, ASST Spedali Civili, Brescia, Italy.
Caratozzolo S; Neurology Unit, Department of Neurological and Vision Sciences, ASST Spedali Civili, Brescia, Italy.
Rozzini L; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Neurology Unit, Department of Neurological and Vision Sciences, ASST Spedali Civili, Brescia, Italy.
Pilotto A; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Neurology Unit, Department of Neurological and Vision Sciences, ASST Spedali Civili, Brescia, Italy.
Benussi A; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Neurology Unit, Department of Neurological and Vision Sciences, ASST Spedali Civili, Brescia, Italy.
Tedeschi G; Neurology Unit, Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli', Naples, Italy.
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Źródło:
Journal of the American Geriatrics Society [J Am Geriatr Soc] 2022 Feb; Vol. 70 (2), pp. 626-628. Date of Electronic Publication: 2021 Nov 09.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Progression*
Eligibility Determination*
Alzheimer Disease/*drug therapy
Antibodies, Monoclonal, Humanized/*therapeutic use
Cognitive Dysfunction/*drug therapy
Aged ; Drug Approval ; Humans ; United States ; United States Food and Drug Administration
Raport
Tytuł:
Hsa_circ_0000437 upregulates and promotes disease progression in rheumatic valvular heart disease.
Autorzy:
Zhu L; Department of Cardiothoracic Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.
Wang Z; Medical School of Ningbo University, Ningbo, China.
Sun L; Department of Cardiothoracic Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.
Zheng D; Department of Cardiothoracic Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.
Hu B; Department of Cardiothoracic Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.
Li N; Department of Cardiothoracic Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.; Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Shao G; Department of Cardiothoracic Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.
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Źródło:
Journal of clinical laboratory analysis [J Clin Lab Anal] 2022 Feb; Vol. 36 (2), pp. e24197. Date of Electronic Publication: 2021 Dec 24.
Typ publikacji:
Journal Article
MeSH Terms:
Disease Progression*
Heart Valve Diseases/*physiopathology
RNA, Circular/*metabolism
Rheumatic Heart Disease/*physiopathology
Cells, Cultured ; Female ; Humans ; Male ; Up-Regulation
Czasopismo naukowe

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