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Tytuł:
Engineered bacteria detect tumor DNA.
Autorzy:
Cooper RM; Synthetic Biology Institute, University of California, San Diego, La Jolla, CA 92093, USA.
Wright JA; Precision Cancer Medicine Theme, South Australia Health and Medical Research Institute, Adelaide, SA 5000, Australia.
Ng JQ; Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
Goyne JM; Precision Cancer Medicine Theme, South Australia Health and Medical Research Institute, Adelaide, SA 5000, Australia.
Suzuki N; Precision Cancer Medicine Theme, South Australia Health and Medical Research Institute, Adelaide, SA 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
Lee YK; Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
Ichinose M; Precision Cancer Medicine Theme, South Australia Health and Medical Research Institute, Adelaide, SA 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
Radford G; Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
Ryan FJ; Precision Cancer Medicine Theme, South Australia Health and Medical Research Institute, Adelaide, SA 5000, Australia.; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.
Kumar S; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
Thomas EM; Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
Vrbanac L; Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
Knight R; Molecular Biology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.; Department of Computer Science and Engineering, University of California, San Diego, La Jolla, CA 92093, USA.; Center for Microbiome Innovation, University of California, San Diego, La Jolla, CA 92093, USA.
Woods SL; Precision Cancer Medicine Theme, South Australia Health and Medical Research Institute, Adelaide, SA 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
Worthley DL; Precision Cancer Medicine Theme, South Australia Health and Medical Research Institute, Adelaide, SA 5000, Australia.; Colonoscopy Clinic, Brisbane, QLD 4000, Australia.
Hasty J; Synthetic Biology Institute, University of California, San Diego, La Jolla, CA 92093, USA.; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.; Molecular Biology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.; Center for Microbiome Innovation, University of California, San Diego, La Jolla, CA 92093, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Aug 11; Vol. 381 (6658), pp. 682-686. Date of Electronic Publication: 2023 Aug 10.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/diagnosis
Colorectal Neoplasms*/genetics
DNA, Neoplasm*/analysis
Acinetobacter*/genetics
Cell-Free Nucleic Acids*/analysis
Biosensing Techniques*
Animals ; Humans ; Mice ; Mutation ; Bioengineering
SCR Organism:
Acinetobacter baylyi
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Quest for Survival: A Review of the Early Biomarkers of Pancreatic Cancer and the Most Effective Approaches at Present.
Autorzy:
Bestari MB; Division of Gastroenterohepatology, Department of Internal Medicine, Hasan Sadikin General Hospital, Faculty of Medicine, University of Padjadjaran, Bandung 40161, Indonesia.
Joewono IR; Mochtar Riady Comprehensive Cancer Center, Siloam Hospitals, Jakarta 12930, Indonesia.
Syam AF; Division of Gastroenterology, Department of Internal Medicine, Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, University of Indonesia, Jakarta 10430, Indonesia.
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Źródło:
Biomolecules [Biomolecules] 2024 Mar 19; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
MicroRNAs*
Pancreatic Neoplasms*/pathology
Humans ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/analysis ; DNA, Neoplasm ; Liquid Biopsy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization and mitigation of artifacts derived from NGS library preparation due to structure-specific sequences in the human genome.
Autorzy:
Chen H; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.; Computer Network Information Center, Chinese Academy of Sciences,, University of Chinese Academy of Sciences, Beijing, 100190, China.; WillingMed Technology Beijing Co., Ltd., Beijing, 100176, China.
Zhang Y; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.
Wang B; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.
Liao R; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.
Duan X; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.; ChosenMed Technology (Zhejiang) Co. Ltd., Zhejiang, 311103, China.
Yang C; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.
Chen J; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.
Hao Y; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.
Shu Y; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.
Cai L; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.
Leng X; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China.
Qian NS; Department of Oncology,Senior Department of Respiratory and Critical Care Medicine, The Eighth Medical Center of Chinese, PLA General Hospital, No.17A Heishanhu Road, Haidian District, Beijing, 100853, China. .
Sun D; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China. .; ChosenMed Technology (Zhejiang) Co. Ltd., Zhejiang, 311103, China. .
Niu B; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China. .; Computer Network Information Center, Chinese Academy of Sciences,, University of Chinese Academy of Sciences, Beijing, 100190, China. .; ChosenMed Technology (Zhejiang) Co. Ltd., Zhejiang, 311103, China. .
Zhou Q; Beijing ChosenMed Clinical Laboratory Company Limited, Jinghai Industrial Park, Economic and Technological Development Area, Beijing, 100176, China. .; ChosenMed Technology (Zhejiang) Co. Ltd., Zhejiang, 311103, China. .
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Źródło:
BMC genomics [BMC Genomics] 2024 Mar 01; Vol. 25 (1), pp. 227. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Artifacts*
Genome, Human*
Humans ; Gene Library ; Sequence Analysis, DNA/methods ; DNA, Neoplasm ; High-Throughput Nucleotide Sequencing/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical Application of Liquid Biopsy in Pancreatic Cancer: A Narrative Review.
Autorzy:
Ramírez-Maldonado E; HBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.; Medicine and Surgery Department, Rovira i Virgili University, 43204 Reus, Spain.
López Gordo S; General Surgery Department, Maresme Health Consortium, 08304 Mataro, Spain.
Major Branco RP; General Surgery at Garcia de Orta's Hospital, 2805-267 Almada, Portugal.
Pavel MC; HBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.; Medicine and Surgery Department, Rovira i Virgili University, 43204 Reus, Spain.
Estalella L; HBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.; Medicine and Surgery Department, Rovira i Virgili University, 43204 Reus, Spain.
Llàcer-Millán E; HBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.; Medicine and Surgery Department, Rovira i Virgili University, 43204 Reus, Spain.
Guerrero MA; HBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.; Medicine and Surgery Department, Rovira i Virgili University, 43204 Reus, Spain.
López-Gordo E; Affinia Therapeutics Inc., Waltham, MA 02453, USA.
Memba R; HBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.; Medicine and Surgery Department, Rovira i Virgili University, 43204 Reus, Spain.
Jorba R; HBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.; Medicine and Surgery Department, Rovira i Virgili University, 43204 Reus, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 29; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pancreatic Neoplasms*/pathology
Carcinoma, Pancreatic Ductal*/pathology
Neoplastic Cells, Circulating*/pathology
Humans ; Endothelial Cells/pathology ; Liquid Biopsy/methods ; DNA, Neoplasm/genetics ; Biomarkers, Tumor/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Use of Multiple Machine Learning Approaches for Selecting Urothelial Cancer-Specific DNA Methylation Biomarkers in Urine.
Autorzy:
Köhler CU; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr University Bochum (IPA), Bürkle-de-la-Camp Platz 1, 44789 Bochum, Germany.
Schork K; Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum and Medical Proteome Analysis, Center for Protein Diagnostics (PRODI), Gesundheitscampus 4, 44081 Bochum, Germany.
Turewicz M; Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum and Medical Proteome Analysis, Center for Protein Diagnostics (PRODI), Gesundheitscampus 4, 44081 Bochum, Germany.
Eisenacher M; Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum and Medical Proteome Analysis, Center for Protein Diagnostics (PRODI), Gesundheitscampus 4, 44081 Bochum, Germany.
Roghmann F; Department of Urology, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Noldus J; Department of Urology, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Marcus K; Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum and Medical Proteome Analysis, Center for Protein Diagnostics (PRODI), Gesundheitscampus 4, 44081 Bochum, Germany.
Brüning T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr University Bochum (IPA), Bürkle-de-la-Camp Platz 1, 44789 Bochum, Germany.
Käfferlein HU; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr University Bochum (IPA), Bürkle-de-la-Camp Platz 1, 44789 Bochum, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 06; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 06.
Typ publikacji:
Journal Article
MeSH Terms:
Body Fluids*
Neoplasms*
Hair Diseases*
Langer-Giedion Syndrome*
Fingers/*abnormalities
Nose/*abnormalities
Male ; Humans ; Biomarkers, Tumor/genetics ; DNA Methylation ; Machine Learning ; DNA, Neoplasm ; Repressor Proteins
SCR Disease Name:
Trichorhinophalangeal Syndrome, Type I
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A comparative study on ctDNA and tumor DNA mutations in lung cancer and benign cases with a high number of CTCs and CTECs.
Autorzy:
Xie J; Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hu B; Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Gong Y; Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
He S; Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lin J; Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Huang Q; Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. huangqian_.
Cheng J; Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Dec 01; Vol. 21 (1), pp. 873. Date of Electronic Publication: 2023 Dec 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lung Neoplasms*/diagnosis
Cell-Free Nucleic Acids*
Humans ; In Situ Hybridization, Fluorescence ; Endothelial Cells ; Biomarkers, Tumor/genetics ; Neoplasm Recurrence, Local ; DNA, Neoplasm/genetics ; Mutation/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Completing a genomic characterisation of microscopic tumour samples with copy number.
Autorzy:
Nulsen J; Weatherall Institute for Molecular Medicine, University of Oxford, Oxford, UK.; Nuffield Department for Women's and Reproductive Health, University of Oxford, Oxford, UK.; Singula Bio Ltd., Oxford, UK.
Hussain N; Weatherall Institute for Molecular Medicine, University of Oxford, Oxford, UK.; Nuffield Department for Women's and Reproductive Health, University of Oxford, Oxford, UK.; Singula Bio Ltd., Oxford, UK.
Al-Deka A; Weatherall Institute for Molecular Medicine, University of Oxford, Oxford, UK.; Nuffield Department for Women's and Reproductive Health, University of Oxford, Oxford, UK.; Singula Bio Ltd., Oxford, UK.
Yap J; University of Birmingham, Birmingham, UK.
Uddin K; University of Birmingham, Birmingham, UK.
Yau C; Nuffield Department for Women's and Reproductive Health, University of Oxford, Oxford, UK.; Health Data Research UK, London, UK.
Ahmed AA; Weatherall Institute for Molecular Medicine, University of Oxford, Oxford, UK. .; Nuffield Department for Women's and Reproductive Health, University of Oxford, Oxford, UK. .; Singula Bio Ltd., Oxford, UK. .; Oxford Biomedical Research Centre, National Institute of Health Research, Oxford, UK. .
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2023 Nov 30; Vol. 24 (1), pp. 453. Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Copy Number Variations*
Neoplasms*/genetics
Neoplasms*/pathology
Humans ; Genome ; Genomics ; DNA, Neoplasm/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tumor-Agnostic Circulating Tumor DNA Testing for Monitoring Muscle-Invasive Bladder Cancer.
Autorzy:
Carrasco R; Laboratori i Servei d'Urologia, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.; Genètica i Tumors Urològics, Fundació de Recerca Clinic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), 08036 Barcelona, Spain.; Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), 08036 Barcelona, Spain.
Ingelmo-Torres M; Laboratori i Servei d'Urologia, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.; Genètica i Tumors Urològics, Fundació de Recerca Clinic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), 08036 Barcelona, Spain.
Trullas R; Unitat de Neurobiologia, Institut d'Investigacions Biomèdiques de Barcelona (IIBB/CSIC/IDIBAPS), 08036 Barcelona, Spain.
Roldán FL; Laboratori i Servei d'Urologia, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.; Genètica i Tumors Urològics, Fundació de Recerca Clinic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), 08036 Barcelona, Spain.
Rodríguez-Carunchio L; Servei d'Anatomia Patològica, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.
Juez L; Laboratori i Servei d'Urologia, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.
Sureda J; Laboratori i Servei d'Urologia, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.
Alcaraz A; Laboratori i Servei d'Urologia, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.; Genètica i Tumors Urològics, Fundació de Recerca Clinic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), 08036 Barcelona, Spain.
Mengual L; Laboratori i Servei d'Urologia, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.; Genètica i Tumors Urològics, Fundació de Recerca Clinic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), 08036 Barcelona, Spain.; Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), 08036 Barcelona, Spain.
Izquierdo L; Laboratori i Servei d'Urologia, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.; Genètica i Tumors Urològics, Fundació de Recerca Clinic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), 08036 Barcelona, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 21; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
Circulating Tumor DNA*/genetics
Cell-Free Nucleic Acids*
Urinary Bladder Neoplasms*/diagnosis
Urinary Bladder Neoplasms*/genetics
Urinary Bladder Neoplasms*/pathology
Humans ; DNA, Neoplasm ; Biomarkers ; Muscles/pathology ; Biomarkers, Tumor/genetics ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Liquid Biopsy in Head and Neck Cancer: Its Present State and Future Role in Africa.
Autorzy:
Temilola DO; Department of Craniofacial Biology, Faculty of Dentistry, University of the Western Cape, Tygerberg Hospital, Cape Town 7505, South Africa.
Adeola HA; Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, University of the Western Cape, Tygerberg Hospital, Cape Town 7505, South Africa.; Division of Dermatology, Department of Medicine, Faculty of Health Sciences and Groote Schuur Hospital, University of Cape Town, Cape Town 7925, South Africa.
Grobbelaar J; Division of Otorhinolaryngology, Department of Surgical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town 7505, South Africa.
Chetty M; Department of Craniofacial Biology, Faculty of Dentistry, University of the Western Cape, Tygerberg Hospital, Cape Town 7505, South Africa.
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Źródło:
Cells [Cells] 2023 Nov 20; Vol. 12 (22). Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Head and Neck Neoplasms*/diagnosis
Humans ; Liquid Biopsy ; Africa ; DNA, Neoplasm ; RNA
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Liquid-based biomarkers in breast cancer: looking beyond the blood.
Autorzy:
Shuai Y; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Ma Z; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Endoscopy, Peking University Cancer Hospital & Institute, Beijing, 100142, China.
Ju J; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Wei T; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Gao S; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Kang Y; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Yang Z; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Wang X; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Yue J; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Yuan P; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Nov 13; Vol. 21 (1), pp. 809. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/diagnosis
Neoplastic Cells, Circulating*/pathology
Humans ; Female ; Biomarkers, Tumor/genetics ; Liquid Biopsy ; DNA, Neoplasm/genetics ; RNA, Neoplasm
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Early detection of hepatocellular carcinoma via no end-repair enzymatic methylation sequencing of cell-free DNA and pre-trained neural network.
Autorzy:
Deng Z; Department of Oncology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ji Y; BamRock Research Department, Suzhou BamRock Biotechnology Ltd., Suzhou, Jiangsu Province, China.
Han B; Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.; Department of Transplantation, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tan Z; Hepatobiliary Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Ren Y; College of Intelligence and Computing, Tianjin University, Tianjin, China.
Gao J; Department of Software Engineering, Tsinghua University, Beijing, China.
Chen N; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Ma C; Suzhou Known Biotechnology Ltd, Suzhou, Jiangsu Province, China.
Zhang Y; Department of Transplantation, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yao Y; Infectious Disease Department, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Lu H; Infectious Disease Department, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Huang H; Infectious Disease Department, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Xu M; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Chen L; Department of Pathology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zheng L; Department of Oncology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Gu J; Department of Oncology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
Xiong D; College of Intelligence and Computing, Tianjin University, Tianjin, China. .
Zhao J; Department of Interventional Medicine, the affiliated hospital of infectious diseases of Soochow University, Suzhou, 215131, Jiangsu Province, China. .
Gu J; Department of Transplantation, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. .; Liver Transplantation Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. .
Chen Z; Infectious Disease Department, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China. .; Suzhou Key Laboratory of Pathogen Bioscience and Anti-Infective Medicine, Suzhou, Jiangsu Province, China. .
Wang K; Hepatobiliary Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China. .
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Źródło:
Genome medicine [Genome Med] 2023 Nov 08; Vol. 15 (1), pp. 93. Date of Electronic Publication: 2023 Nov 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/diagnosis
Carcinoma, Hepatocellular*/genetics
Liver Neoplasms*/diagnosis
Liver Neoplasms*/genetics
Cell-Free Nucleic Acids*/genetics
Humans ; Biomarkers, Tumor/genetics ; DNA, Neoplasm ; DNA Methylation ; Neural Networks, Computer
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Calibration-Aimed Comparison of Image-Cytometry- and Flow-Cytometry-Based Approaches of Ploidy Analysis.
Autorzy:
Jónás VZ; Image Analysis Department, 3DHISTECH Ltd., 1141 Budapest, Hungary.
Paulik R; Image Analysis Department, 3DHISTECH Ltd., 1141 Budapest, Hungary.
Kozlovszky M; Department of BioTech Research Center, Óbuda University, 1034 Budapest, Hungary.
Molnár B; Image Analysis Department, 3DHISTECH Ltd., 1141 Budapest, Hungary.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2022 Sep 14; Vol. 22 (18). Date of Electronic Publication: 2022 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
DNA, Neoplasm*/genetics
Ploidies*
Calibration ; Flow Cytometry ; Image Processing, Computer-Assisted ; Reproducibility of Results
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Liquid biopsy techniques and pancreatic cancer: diagnosis, monitoring, and evaluation.
Autorzy:
Wang K; Department of Organ Transplantation and Hepatobiliary, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
Wang X; Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, 410008, China.
Pan Q; Department of Organ Transplantation and Hepatobiliary, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China. .
Zhao B; Department of Ultrasound, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2023 Oct 06; Vol. 22 (1), pp. 167. Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pancreatic Neoplasms*/diagnosis
Pancreatic Neoplasms*/genetics
Neoplastic Cells, Circulating*/pathology
Humans ; Biomarkers, Tumor/genetics ; Liquid Biopsy/methods ; DNA, Neoplasm ; Pancreatic Neoplasms
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CTC, ctDNA, and Exosome in Thyroid Cancers: A Review.
Autorzy:
Wang W; Division of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Zheng Z; Division of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.; Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Lei J; Division of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 06; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Exosomes*/genetics
Thyroid Neoplasms*/diagnosis
Thyroid Neoplasms*/genetics
Humans ; DNA, Neoplasm ; Liquid Biopsy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Functional Role of Mitochondrial DNA in Cancer Progression.
Autorzy:
Lin YH; Liver Research Center, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Lim SN; Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Chen CY; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
Chi HC; Graduate Institute of Integrated Medicine, China Medical University, Taichung 404, Taiwan.; Chinese Medicine Research Center, China Medical University, Taichung 404, Taiwan.
Yeh CT; Liver Research Center, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of Hepatology and Gastroenterology, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.; Molecular Medicine Research Center, Chang Gung University, Taoyuan 333, Taiwan.
Lin WR; Liver Research Center, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of Hepatology and Gastroenterology, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 31; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 31.
Typ publikacji:
Journal Article; Review
MeSH Terms:
DNA, Mitochondrial*/genetics
DNA, Mitochondrial*/metabolism
DNA, Neoplasm*/genetics
DNA, Neoplasm*/metabolism
Mitochondria*/genetics
Mitochondria*/metabolism
Mutation*
Neoplasms*/genetics
Neoplasms*/metabolism
Polymorphism, Single Nucleotide*
Humans ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Silico Investigation of the Biological Implications of Complex DNA Damage with Emphasis in Cancer Radiotherapy through a Systems Biology Approach.
Autorzy:
Pavlopoulou A; Izmir Biomedicine and Genome Center, Balcova, Izmir 35340, Turkey.; Izmir International Biomedicine and Genome Institute, Genomics and Molecular Biotechnology Department, Dokuz Eylül University, Balcova, Izmir 35220, Turkey.
Asfa S; Izmir Biomedicine and Genome Center, Balcova, Izmir 35340, Turkey.; Izmir International Biomedicine and Genome Institute, Genomics and Molecular Biotechnology Department, Dokuz Eylül University, Balcova, Izmir 35220, Turkey.
Gioukakis E; Physics Department, School of Applied Mathematical and Physical Sciences, National Technical University of Athens (NTUA), 15780 Zografou, Greece.
Mavragani IV; Physics Department, School of Applied Mathematical and Physical Sciences, National Technical University of Athens (NTUA), 15780 Zografou, Greece.
Nikitaki Z; Physics Department, School of Applied Mathematical and Physical Sciences, National Technical University of Athens (NTUA), 15780 Zografou, Greece.
Takan I; Izmir Biomedicine and Genome Center, Balcova, Izmir 35340, Turkey.; Izmir International Biomedicine and Genome Institute, Genomics and Molecular Biotechnology Department, Dokuz Eylül University, Balcova, Izmir 35220, Turkey.
Pouget JP; IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, 34298 Montpellier, France.
Harrison L; Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA.
Georgakilas AG; Physics Department, School of Applied Mathematical and Physical Sciences, National Technical University of Athens (NTUA), 15780 Zografou, Greece.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Dec 15; Vol. 26 (24). Date of Electronic Publication: 2021 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
DNA Repair*
DNA, Neoplasm*/genetics
DNA, Neoplasm*/metabolism
Neoplasms*/genetics
Neoplasms*/metabolism
Neoplasms*/radiotherapy
Systems Biology*
Humans ; Radiation, Ionizing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Epitachophoresis is a novel versatile total nucleic acid extraction method.
Autorzy:
Datinska V; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Gheibi P; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Jefferson K; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Yang J; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Paladugu S; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Dallett C; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Voracova I; Institute of Analytical Chemistry, Czech Academy of Sciences, 602 00, Brno, Czech Republic.
Foret F; Institute of Analytical Chemistry, Czech Academy of Sciences, 602 00, Brno, Czech Republic.
Astier Y; Roche Sequencing Solution, Pleasanton, CA, 94588, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 23; Vol. 11 (1), pp. 22736. Date of Electronic Publication: 2021 Nov 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms/*genetics
DNA, Neoplasm/*isolation & purification
High-Throughput Nucleotide Sequencing/*methods
Lung Neoplasms/*genetics
RNA, Neoplasm/*isolation & purification
Colorectal Neoplasms/pathology ; DNA, Neoplasm/analysis ; DNA, Neoplasm/chemistry ; Humans ; Lung Neoplasms/pathology ; RNA, Neoplasm/analysis ; RNA, Neoplasm/chemistry ; Tissue Fixation ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding.
Autorzy:
Maračić S; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10000 Zagreb, Croatia.
Grbčić P; Department of Biotechnology, University of Rijeka, Ulica Radmile Matejčić 2, HR-51000 Rijeka, Croatia.
Shammugam S; Division of Organic Chemistry and Biochemistry, Laboratory for Biomolecular Interactions and Spectroscopy, Ruđer Bošković Institute, Bijenička 54, HR-10000 Zagreb, Croatia.
Radić Stojković M; Division of Organic Chemistry and Biochemistry, Laboratory for Biomolecular Interactions and Spectroscopy, Ruđer Bošković Institute, Bijenička 54, HR-10000 Zagreb, Croatia.
Pavelić K; Faculty of Medicine, Juraj Dobrila University of Pula, HR-52100 Pula, Croatia.
Sedić M; Centre for Applied Bioanthropology, Institute for Anthropological Research, Ljudevita Gaja 32, HR-10000 Zagreb, Croatia.
Kraljević Pavelić S; Faculty of Health Studies, University of Rijeka, Ulica Viktora Cara Emina 5, HR-51000 Rijeka, Croatia.
Raić-Malić S; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10000 Zagreb, Croatia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Nov 22; Vol. 26 (22). Date of Electronic Publication: 2021 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Proliferation*
DNA, Neoplasm*/chemistry
DNA, Neoplasm*/metabolism
Intercalating Agents*/chemical synthesis
Intercalating Agents*/chemistry
Intercalating Agents*/pharmacology
Neoplasms*/drug therapy
Neoplasms*/metabolism
Oximes/*chemistry
A549 Cells ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; HeLa Cells ; Hep G2 Cells ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
lncRNA GAS5 Sensitizes Breast Cancer Cells to Ionizing Radiation by Inhibiting DNA Repair.
Autorzy:
Ma Y; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
Yu L; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
Yan W; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
Qiu L; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
Zhang J; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
Jia X; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
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Źródło:
BioMed research international [Biomed Res Int] 2022 Jan 11; Vol. 2022, pp. 1987519. Date of Electronic Publication: 2022 Jan 11 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
DNA Repair*
X-Rays*
Breast Neoplasms/*metabolism
DNA, Neoplasm/*metabolism
RNA, Long Noncoding/*metabolism
RNA, Neoplasm/*metabolism
Breast Neoplasms/genetics ; DNA, Neoplasm/genetics ; Female ; Humans ; MCF-7 Cells ; RNA, Long Noncoding/genetics ; RNA, Neoplasm/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Urine DNA for monitoring chemoradiotherapy response in muscle-invasive bladder cancer: a pilot study.
Autorzy:
Gordon NS; Bladder Cancer Research Centre, Institute of Cancer & Genomic Sciences, University of Birmingham, Birmingham, UK.
Baxter LA; Department of Computer Science, University of Warwick, Coventry, UK.
Goel A; Bladder Cancer Research Centre, Institute of Cancer & Genomic Sciences, University of Birmingham, Birmingham, UK.
Arnold R; Bladder Cancer Research Centre, Institute of Cancer & Genomic Sciences, University of Birmingham, Birmingham, UK.
Kaur B; Cancer Research UK Clinical Trials Unit, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Liu W; Cancer Research UK Clinical Trials Unit, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Pirrie SJ; Cancer Research UK Clinical Trials Unit, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Hussain S; Department of Oncology and Metabolism, The Medical School, Sheffield, UK.
Viney R; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Ford D; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Zarkar A; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Wood MA; Phase Genomics Inc., Seattle, WA, USA.
Mitin T; Department of Radiation Medicine, Oregon Health and Science University, Portland, OR, USA.
Thompson RF; Department of Radiation Medicine, Oregon Health and Science University, Portland, OR, USA.
James ND; The Institute of Cancer Research, London, UK.
Ward DG; Bladder Cancer Research Centre, Institute of Cancer & Genomic Sciences, University of Birmingham, Birmingham, UK.
Bryan RT; Bladder Cancer Research Centre, Institute of Cancer & Genomic Sciences, University of Birmingham, Birmingham, UK.
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Źródło:
BJU international [BJU Int] 2022 Jan; Vol. 129 (1), pp. 32-34. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
DNA, Neoplasm/*urine
Neoplasm Recurrence, Local/*urine
Urinary Bladder Neoplasms/*therapy
Urinary Bladder Neoplasms/*urine
Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biomarkers, Tumor/urine ; Cetuximab/administration & dosage ; Chemoradiotherapy ; Clinical Trials, Phase I as Topic ; Clinical Trials, Phase II as Topic ; DNA, Neoplasm/analysis ; Fluorouracil/administration & dosage ; Humans ; Liquid Biopsy ; Mitomycin/administration & dosage ; Muscle, Smooth/pathology ; Mutation ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local/genetics ; Pilot Projects ; Receptor, Fibroblast Growth Factor, Type 3/genetics ; Sequence Analysis, DNA ; Telomerase/genetics ; Treatment Outcome ; Tumor Suppressor Protein p53/genetics ; Urinary Bladder Neoplasms/genetics ; Urinary Bladder Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 3282

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