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Wyszukujesz frazę ""DNA Adducts"" wg kryterium: Temat


Tytuł :
Genotoxic effect of meat consumption: A mini review.
Autorzy :
Pelland-St-Pierre L; Department of Social and Preventive Medicine, École de Santé Publique de l'Université de Montréal (ESPUM), Université de Montréal, Montréal, Québec, Canada; Health Innovation and Evaluation Hub, Université de Montréal Hospital Research Centre (CRCHUM), Montréal, Québec, Canada.
Sernoskie SC; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.
Verner MA; Centre de recherche en santé publique (CReSP), Université de Montréal, Montréal, Québec, Canada; Department of Occupational and Environmental Health, École de Santé Publique de l'Université de Montréal (ESPUM), Université de Montréal, Montréal, Québec, Canada.
Ho V; Department of Social and Preventive Medicine, École de Santé Publique de l'Université de Montréal (ESPUM), Université de Montréal, Montréal, Québec, Canada; Health Innovation and Evaluation Hub, Université de Montréal Hospital Research Centre (CRCHUM), Montréal, Québec, Canada. Electronic address: .
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Źródło :
Mutation research [Mutat Res] 2021 Mar-Apr; Vol. 863-864, pp. 503311. Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
DNA Adducts*
DNA Damage*
Food Preferences*
Red Meat/*adverse effects
Comet Assay ; Humans ; Micronucleus Tests
Czasopismo naukowe
Tytuł :
Investigation by mass spectrometry and P post-labelling of DNA adducts formation from 1,2-naphthoquinone, an oxydated metabolite of naphthalene.
Autorzy :
Clergé A; Normandy University, UNICAEN, UNIROUEN, ABTE, Caen, France. Electronic address: .
Le Goff J; ADn'tox SAS, Caen, France.
Lopez-Piffet C; Normandy University, UNICAEN, UNIROUEN, ABTE, Caen, France; Normandy University, UNICAEN, PRISMM Platform ICORE, Caen, France.
Meier S; Institute of Marine Research, Bergen, Norway.
Lagadu S; Normandy University, UNICAEN, UNIROUEN, ABTE, Caen, France; Normandy University, UNICAEN, PRISMM Platform ICORE, Caen, France; Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
Vaudorne I; Normandy University, UNICAEN, UNIROUEN, ABTE, Caen, France; Normandy University, UNICAEN, PRISMM Platform ICORE, Caen, France; Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
Babin V; Normandy University, UNICAEN, Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), 14000, Caen, France.
Cailly T; Normandy University, UNICAEN, Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), 14000, Caen, France; Normandy University, UNICAEN, IMOGERE, Caen, France; Department of Nuclear Medicine, CHU Côte de Nacre, Caen, France.
Delépée R; Normandy University, UNICAEN, UNIROUEN, ABTE, Caen, France; Normandy University, UNICAEN, PRISMM Platform ICORE, Caen, France; Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2021 Jan; Vol. 263, pp. 128079. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Adducts*
Naphthoquinones*
Chromatography, High Pressure Liquid ; Naphthalenes ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Advances in sulfur mustard-induced DNA adducts: Characterization and detection.
Autorzy :
Cheng X; Department of Biology and Chemistry, College of Liberal Arts and Sciences, National University of Defense Technology, Changsha, 410073, PR China; State Key Laboratory of NBC Protection for Civilian, Beijing, 102205, PR China.
Liu C; State Key Laboratory of NBC Protection for Civilian, Beijing, 102205, PR China.
Yang Y; State Key Laboratory of NBC Protection for Civilian, Beijing, 102205, PR China.
Liang L; State Key Laboratory of NBC Protection for Civilian, Beijing, 102205, PR China.
Chen B; State Key Laboratory of NBC Protection for Civilian, Beijing, 102205, PR China.
Yu H; State Key Laboratory of NBC Protection for Civilian, Beijing, 102205, PR China.
Xia J; State Key Laboratory of NBC Protection for Civilian, Beijing, 102205, PR China.
Liu S; State Key Laboratory of NBC Protection for Civilian, Beijing, 102205, PR China. Electronic address: .
Li Y; Department of Biology and Chemistry, College of Liberal Arts and Sciences, National University of Defense Technology, Changsha, 410073, PR China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Jun 15; Vol. 344, pp. 46-57. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Adducts*
Chemical Warfare Agents/*toxicity
Mustard Gas/*toxicity
Animals ; Biomarkers/blood ; Humans
Czasopismo naukowe
Tytuł :
Estragole: DNA adduct formation in primary rat hepatocytes and genotoxic potential in HepG2-CYP1A2 cells.
Autorzy :
Schulte-Hubbert R; Food Chemistry and Toxicology, University of Kaiserslautern, Kaiserslautern, Germany.
Küpper JH; Molecular Cell Biology, Brandenburg University of Technology, Senftenberg, Germany.
Thomas AD; Centre for the Research in Biosciences (CRIB), UWE, Bristol, United Kingdom.
Schrenk D; Food Chemistry and Toxicology, University of Kaiserslautern, Kaiserslautern, Germany. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2020 Nov; Vol. 444, pp. 152566. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Adducts*
Anisoles/*toxicity
Carcinogens/*toxicity
Hepatocytes/*drug effects
Animals ; Cells, Cultured ; Cytochrome P-450 CYP1A2/genetics ; Hepatocytes/metabolism ; Humans ; Male ; Micronucleus Tests ; Rats, Wistar
Czasopismo naukowe
Tytuł :
The DNA damage-sensing NER repair factor XPC-RAD23B does not recognize bulky DNA lesions with a missing nucleotide opposite the lesion.
Autorzy :
Feher KM; Chemistry Department, New York University, 100 Washington East, New York, NY, 10003-5180, USA.
Kolbanovskiy A; Chemistry Department, New York University, 100 Washington East, New York, NY, 10003-5180, USA.
Durandin A; Chemistry Department, New York University, 100 Washington East, New York, NY, 10003-5180, USA.
Shim Y; Department of Chemistry & Biochemistry, Baylor University, Waco, TX, 76706, USA.
Min JH; Department of Chemistry & Biochemistry, Baylor University, Waco, TX, 76706, USA.
Lee YC; Chemistry Department, New York University, 100 Washington East, New York, NY, 10003-5180, USA.
Shafirovich V; Chemistry Department, New York University, 100 Washington East, New York, NY, 10003-5180, USA.
Mu H; Department of Biology, New York University, 100 Washington Square East, New York, N.Y., 10003-5180, USA.
Broyde S; Department of Biology, New York University, 100 Washington Square East, New York, N.Y., 10003-5180, USA.
Geacintov NE; Chemistry Department, New York University, 100 Washington East, New York, NY, 10003-5180, USA. Electronic address: .
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Źródło :
DNA repair [DNA Repair (Amst)] 2020 Dec; Vol. 96, pp. 102985. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA Repair*
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide/*metabolism
DNA Adducts/*metabolism
DNA-Binding Proteins/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide/chemistry ; DNA/chemistry ; DNA/metabolism ; DNA Adducts/chemistry ; DNA Repair Enzymes/metabolism ; DNA-Binding Proteins/chemistry ; Humans ; Kinetics ; Molecular Dynamics Simulation ; Nucleic Acid Conformation ; Protein Conformation ; Saccharomyces cerevisiae/enzymology ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/chemistry ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Insights into the Direct Oxidative Repair of Etheno Lesions: MD and QM/MM Study on the Substrate Scope of ALKBH2 and AlkB.
Autorzy :
Lenz SAP; Department of Chemistry and Biochemistry, University of Lethbridge, 4401 University Drive West, Lethbridge, Alberta, T1K 3M4, Canada.
Li D; Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI, 02881, USA.
Wetmore SD; Department of Chemistry and Biochemistry, University of Lethbridge, 4401 University Drive West, Lethbridge, Alberta, T1K 3M4, Canada. Electronic address: .
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Źródło :
DNA repair [DNA Repair (Amst)] 2020 Dec; Vol. 96, pp. 102944. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Catalytic Domain*
DNA Repair*
Molecular Dynamics Simulation*
AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase/*metabolism
DNA Adducts/*metabolism
Escherichia coli Proteins/*metabolism
Mixed Function Oxygenases/*metabolism
Adenine/analogs & derivatives ; Adenine/metabolism ; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase/chemistry ; Computational Biology ; Cytosine/analogs & derivatives ; Cytosine/metabolism ; DNA Adducts/chemistry ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Escherichia coli Proteins/chemistry ; Guanine/analogs & derivatives ; Guanine/metabolism ; Humans ; Mixed Function Oxygenases/chemistry ; Models, Molecular ; Protein Conformation ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Treatment of human cells with 5-aza-dC induces formation of PARP1-DNA covalent adducts at genomic regions targeted by DNMT1.
Autorzy :
Kiianitsa K; Department of Immunology, University of Washington, Seattle, WA, 98195, USA.
Zhang Y; Department of Immunology, University of Washington, Seattle, WA, 98195, USA.
Maizels N; Department of Immunology, University of Washington, Seattle, WA, 98195, USA; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA. Electronic address: .
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Źródło :
DNA repair [DNA Repair (Amst)] 2020 Dec; Vol. 96, pp. 102977. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
CpG Islands*
Azacitidine/*pharmacology
DNA (Cytosine-5-)-Methyltransferase 1/*metabolism
DNA Adducts/*metabolism
Hematologic Neoplasms/*drug therapy
Poly (ADP-Ribose) Polymerase-1/*chemistry
Antimetabolites, Antineoplastic/pharmacology ; Antimetabolites, Antineoplastic/therapeutic use ; Azacitidine/toxicity ; Cells, Cultured ; DNA/drug effects ; DNA/metabolism ; DNA Adducts/chemistry ; DNA Methylation ; Hematologic Neoplasms/genetics ; Hematologic Neoplasms/metabolism ; Humans ; K562 Cells
Czasopismo naukowe
Tytuł :
PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts.
Autorzy :
Piberger AL; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK. .
Bowry A; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Kelly RDW; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Walker AK; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
González-Acosta D; Molecular Oncology Program, Spanish National Cancer Research Centre, Madrid, Spain.
Bailey LJ; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9RQ, UK.
Doherty AJ; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9RQ, UK.
Méndez J; Molecular Oncology Program, Spanish National Cancer Research Centre, Madrid, Spain.
Morris JR; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Bryant HE; Department of Oncology & Metabolism, The Medical School, University of Sheffield, Sheffield, S10 2RX, UK.
Petermann E; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 17; Vol. 11 (1), pp. 5863. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Adducts/*genetics
DNA Primase/*metabolism
DNA-Directed DNA Polymerase/*metabolism
Homologous Recombination/*physiology
Multifunctional Enzymes/*metabolism
4-Nitroquinoline-1-oxide/toxicity ; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide/metabolism ; Benz(a)Anthracenes/administration & dosage ; Benz(a)Anthracenes/toxicity ; Cell Line ; DNA Adducts/metabolism ; DNA Primase/genetics ; DNA, Single-Stranded ; DNA-Directed DNA Polymerase/genetics ; Humans ; Multifunctional Enzymes/genetics ; Quinolones/toxicity ; Rad51 Recombinase/genetics ; Rad51 Recombinase/metabolism ; Single Molecule Imaging ; Sister Chromatid Exchange
Czasopismo naukowe
Tytuł :
Translesion synthesis of 6-nitrochrysene-derived 2'-deoxyadenosine adduct in human cells.
Autorzy :
Powell BV; Department of Chemistry, University of Connecticut, Storrs, CT 06269, United States.
Bacurio JHT; Department of Chemistry, University of Connecticut, Storrs, CT 06269, United States.
Basu AK; Department of Chemistry, University of Connecticut, Storrs, CT 06269, United States. Electronic address: .
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Źródło :
DNA repair [DNA Repair (Amst)] 2020 Nov; Vol. 95, pp. 102935. Date of Electronic Publication: 2020 Jul 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA Repair*
Chrysenes/*chemistry
DNA Adducts/*metabolism
DNA-Binding Proteins/*metabolism
DNA-Directed DNA Polymerase/*metabolism
Deoxyadenosines/*chemistry
DNA Adducts/chemistry ; DNA Replication ; HEK293 Cells ; Humans
Czasopismo naukowe
Tytuł :
Thermodynamic Insights by Microscale Thermophoresis into Translesion DNA Synthesis Catalyzed by DNA Polymerases Across a Lesion of Antitumor Platinum-Acridine Complex.
Autorzy :
Hreusova M; Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, CZ-61265 Brno, Czech Republic.; Department of Biophysics, Faculty of Science, Palacky University, Slechtitelu 27, CZ 78371 Olomouc, Czech Republic.
Novakova O; Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, CZ-61265 Brno, Czech Republic.
Brabec V; Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, CZ-61265 Brno, Czech Republic.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 21; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Adducts/*chemistry
DNA-Directed DNA Polymerase/*metabolism
Platinum Compounds/*pharmacology
Acridines/chemistry ; Acridines/pharmacology ; Biocatalysis ; Catalysis ; DNA/biosynthesis ; DNA Adducts/genetics ; DNA Adducts/metabolism ; DNA Repair ; DNA Replication ; Guanine/metabolism ; Nucleotides/genetics ; Nucleotides/metabolism ; Platinum Compounds/chemistry ; Thermal Diffusion ; Thermodynamics
Czasopismo naukowe
Tytuł :
DNA as an in vitro trapping agent for detection of bulky genotoxic metabolites.
Autorzy :
Motwani HV; Department of Environmental Science, Stockholm University, SE-106 91 Stockholm, Sweden. Electronic address: .
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Źródło :
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2020 Sep 01; Vol. 1152, pp. 122276. Date of Electronic Publication: 2020 Jul 18.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Adducts*/analysis
DNA Adducts*/chemistry
DNA Adducts*/metabolism
Mutagens*/analysis
Mutagens*/chemistry
Mutagens*/metabolism
DNA/*metabolism
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide/analysis ; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide/chemistry ; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide/metabolism ; Animals ; Benzo(a)pyrene/analysis ; Benzo(a)pyrene/chemistry ; Benzo(a)pyrene/metabolism ; Chromatography, Liquid/methods ; Linear Models ; Mass Spectrometry/methods ; Microsomes, Liver/metabolism ; Models, Chemical ; Rats ; Reproducibility of Results ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Protective Role of Glutathione against Peroxynitrite-Mediated DNA Damage During Acute Inflammation.
Autorzy :
Ahmed N
Chakrabarty A
Guengerich FP; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, United States.
Chowdhury G
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2020 Oct 19; Vol. 33 (10), pp. 2668-2674. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA/*drug effects
DNA Adducts/*drug effects
Glutathione/*pharmacology
Inflammation/*physiopathology
Peroxynitrous Acid/*adverse effects
Acute Disease ; Animals ; Betacoronavirus ; COVID-19 ; Cattle ; Coronavirus Infections/drug therapy ; DNA/chemistry ; DNA Adducts/chemistry ; DNA Damage ; Glutathione/chemistry ; HEK293 Cells ; Humans ; Mutagens/chemistry ; Mutagens/pharmacology ; Pandemics ; Peroxynitrous Acid/chemistry ; Pneumonia, Viral/drug therapy ; SARS-CoV-2 ; Salmonella typhimurium/genetics
Czasopismo naukowe
Tytuł :
Synthesis of Oligonucleotides containing the cis-Interstrand Crosslink Produced by Mitomycins in their Reaction with DNA.
Autorzy :
Aguilar W; Science Department, John Jay College of Criminal Justice, 524 West 59th street, New York, NY, 10019, USA.
Zacarias O; Science Department, John Jay College of Criminal Justice, 524 West 59th street, New York, NY, 10019, USA.
Romaine M; Science Department, John Jay College of Criminal Justice, 524 West 59th street, New York, NY, 10019, USA.
Proni G; Science Department, John Jay College of Criminal Justice, 524 West 59th street, New York, NY, 10019, USA.
Petrovic AG; New York Institute of Technology, 1855 Broadway, EGGC 405A, New York, NY, 10023, USA.
Abzalimov R; City University of New York, Advanced Research Center, 85 St Nicholas Terrace, New York, NY, 10031, USA.; Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY, 10016, USA.
Paz MM; Departamento de Química Orgánica, Facultad de Química, Universidade de Santiago de Compostela, Santiago de Compostela, A Coruña, 15782, Spain.
Champeil E; Science Department, John Jay College of Criminal Justice, 524 West 59th street, New York, NY, 10019, USA.; Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY, 10016, USA.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Oct 01; Vol. 26 (55), pp. 12570-12578. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Adducts*
Oligonucleotides*/chemical synthesis
Oligonucleotides*/chemistry
Mitomycins/*chemistry
DNA/chemistry ; DNA Damage
Czasopismo naukowe
Tytuł :
Aristolochic acid and its effect on different cancers in uro-oncology.
Autorzy :
Rebhan K; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Austria.
Ertl IE; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Austria.
Shariat SF; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Austria.; Department of Urology, Weill Cornell Medical College, New York, New York.; Department of Urology, University of Texas Southwestern, Dallas, Texas, USA.; Department of Urology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; Institute for Urology and Reproductive Health, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.; Division of Urology, Department of Special Surgery, Jordan University Hospital, The University of Jordan, Amman, Jordan.
Grollman AP; Department of Pharmacological Sciences.; Department of Medicine, Stony Brook University, Stony Brook, New York, USA.
Rosenquist T; Department of Pharmacological Sciences.
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Źródło :
Current opinion in urology [Curr Opin Urol] 2020 Sep; Vol. 30 (5), pp. 689-695.
Typ publikacji :
Journal Article
MeSH Terms :
Aristolochic Acids/*toxicity
Balkan Nephropathy/*chemically induced
DNA Adducts/*metabolism
Drugs, Chinese Herbal/*adverse effects
Urinary Bladder Neoplasms/*chemically induced
Urologic Neoplasms/*chemically induced
Carcinogens ; DNA Adducts/genetics ; Humans
Czasopismo naukowe
Tytuł :
Agnostic Cys34-albumin adductomics and DNA methylation: Implication of N-acetylcysteine in lung carcinogenesis years before diagnosis.
Autorzy :
Dagnino S; MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Bodinier B; MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Grigoryan H; School of Public Health, University of California, Berkeley, CA.
Rappaport SM; School of Public Health, University of California, Berkeley, CA.
Karimi M; MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Guida F; International Agency for Research on Cancer (IARC), Lyon, France.
Polidoro S; IIGM, Italian Institute for Genomic Medicine, Torino, Italy.
Edmands WB; School of Public Health, University of California, Berkeley, CA.
Naccarati A; IIGM, Italian Institute for Genomic Medicine, Torino, Italy.
Fiorito G; IIGM, Italian Institute for Genomic Medicine, Torino, Italy.
Sacerdote C; Piedmont Reference Centre for Epidemiology and Cancer Prevention (CPO Piemonte), Turin, Italy.
Krogh V; Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
Vermeulen R; MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Vineis P; MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; IIGM, Italian Institute for Genomic Medicine, Torino, Italy.
Chadeau-Hyam M; MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
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Źródło :
International journal of cancer [Int J Cancer] 2020 Jun 15; Vol. 146 (12), pp. 3294-3303. Date of Electronic Publication: 2019 Oct 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcysteine/*metabolism
Carcinogenesis/*genetics
DNA Adducts/*blood
Lung Neoplasms/*epidemiology
Smoking/*adverse effects
Biomarkers, Tumor/blood ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Case-Control Studies ; CpG Islands/genetics ; DNA Adducts/genetics ; DNA Adducts/metabolism ; DNA Methylation ; Epigenomics/methods ; Female ; Follow-Up Studies ; Humans ; Lung Neoplasms/blood ; Lung Neoplasms/genetics ; Male ; Middle Aged ; Oxidation-Reduction ; Prospective Studies ; Risk Assessment/methods ; Smoking/blood ; Smoking/genetics
Czasopismo naukowe
Tytuł :
Detection of the thietane precursor in the UVA formation of the DNA 6-4 photoadduct.
Autorzy :
Ortiz-Rodríguez LA; Department of Chemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
Reichardt C; Department of Chemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
Hoehn SJ; Department of Chemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
Jockusch S; Department of Chemistry, Columbia University, New York, NY, 10027, USA.
Crespo-Hernández CE; Department of Chemistry, Case Western Reserve University, Cleveland, OH, 44106, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Jul 17; Vol. 11 (1), pp. 3599. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA/*genetics
DNA Adducts/*genetics
Skin Neoplasms/*genetics
Thionucleosides/*chemistry
Thymidine/*analogs & derivatives
Ultraviolet Rays/*adverse effects
DNA/chemistry ; DNA Adducts/radiation effects ; Humans ; Molecular Structure ; Nucleic Acid Conformation/radiation effects ; Skin Neoplasms/etiology ; Thymidine/chemistry
Czasopismo naukowe
Tytuł :
Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs topoisomerase 1 DNA-protein crosslinks and 3'-blocking lesions in the absence of tyrosyl-DNA phosphodiesterase 1 (TDP1).
Autorzy :
Tsuda M; Program of Mathematical and Life Sciences, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima 739-8526, Japan. Electronic address: .
Kitamasu K; Program of Mathematical and Life Sciences, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima 739-8526, Japan.
Kumagai C; Program of Mathematical and Life Sciences, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima 739-8526, Japan.
Sugiyama K; Program of Mathematical and Life Sciences, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima 739-8526, Japan.
Nakano T; DNA Damage Chemistry Research Group, Institute for Quantum Life Science, National Institutes of Quantum and Radiological Science and Technology, 8-1-7 Umemidai, Kizugawa-shi, Kyoto 619-0215, Japan.
Ide H; Program of Mathematical and Life Sciences, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima 739-8526, Japan. Electronic address: .
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Źródło :
DNA repair [DNA Repair (Amst)] 2020 Jul - Aug; Vol. 91-92, pp. 102849. Date of Electronic Publication: 2020 May 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Repair*
Camptothecin/*pharmacology
DNA Adducts/*metabolism
DNA Topoisomerases, Type I/*chemistry
DNA-Binding Proteins/*metabolism
Phosphoric Diester Hydrolases/*metabolism
Cell Line, Tumor ; DNA/chemistry ; DNA Adducts/chemistry ; DNA-Binding Proteins/genetics ; Gene Deletion ; Humans ; Phosphoric Diester Hydrolases/genetics ; Proteasome Endopeptidase Complex
Czasopismo naukowe
Tytuł :
BP[dG]-induced distortions to DNA polymerase and DNA duplex: A detailed mechanism of BP adducts blocking replication.
Autorzy :
Wu Z; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Peng L; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Hu Y; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Xie T; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Yan H; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Wan H; College of Mathematics and Informatics, South China Agricultural University, Guangzhou, China.
Liu W; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Liang L; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Xie Z; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Liu K; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Shi H; Laboratory of Tumor Targeted and Immune Therapy, Clinical Research Center for Breast, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China. Electronic address: .
Zhao G; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China. Electronic address: .
Hu J; College of Pharmacy and Biological Engineering, Sichuan Industrial Institute of Antibiotics, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China. Electronic address: .
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2020 Jun; Vol. 140, pp. 111325. Date of Electronic Publication: 2020 Apr 06.
Typ publikacji :
Journal Article
MeSH Terms :
Benzo(a)pyrene/*chemistry
DNA/*drug effects
DNA Adducts/*chemistry
Deoxyguanosine/*chemistry
Benzo(a)pyrene/toxicity ; DNA Adducts/toxicity ; Humans ; Hydrogen Bonding ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Cross-linking of the DNA repair protein O -alkylguanine DNA alkyltransferase to DNA in the presence of cisplatin.
Autorzy :
Ming X; Department of Medicinal Chemistry and the Masonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA.
Michaelson-Richie ED; Department of Medicinal Chemistry and the Masonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA.
Groehler AS 4th; Center for Genomic Integrity, Institute for Basic Science, Ulsan, Republic of Korea.
Villalta PW; Mass Spectrometry Core at the Masonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA.
Campbell C; Department of Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA.
Tretyakova NY; Department of Medicinal Chemistry and the Masonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA. Electronic address: .
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Źródło :
DNA repair [DNA Repair (Amst)] 2020 May; Vol. 89, pp. 102840. Date of Electronic Publication: 2020 Mar 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Adducts*
Models, Molecular*
Cisplatin/*pharmacology
DNA/*chemistry
O(6)-Methylguanine-DNA Methyltransferase/*chemistry
Antineoplastic Agents/pharmacology ; Chromatography, High Pressure Liquid ; Cross-Linking Reagents/pharmacology ; Humans ; Protein Conformation ; Recombinant Proteins ; Sequence Analysis, Protein ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase.
Autorzy :
Reed L; Department of Analytical, Environmental and Forensic Sciences, MRC-PHE Centre for Environment and Health, King's College London, London, SE1 9NH, United Kingdom.
Jarvis IWH; Department of Analytical, Environmental and Forensic Sciences, MRC-PHE Centre for Environment and Health, King's College London, London, SE1 9NH, United Kingdom.
Phillips DH; Department of Analytical, Environmental and Forensic Sciences, MRC-PHE Centre for Environment and Health, King's College London, London, SE1 9NH, United Kingdom; NIHR Health Protection Research Unit in Health Impact of Environmental Hazards, King's College London in Partnership With Public Health England and Imperial College London, London, SE1 9NH, United Kingdom.
Arlt VM; Department of Analytical, Environmental and Forensic Sciences, MRC-PHE Centre for Environment and Health, King's College London, London, SE1 9NH, United Kingdom; NIHR Health Protection Research Unit in Health Impact of Environmental Hazards, King's College London in Partnership With Public Health England and Imperial College London, London, SE1 9NH, United Kingdom. Electronic address: .
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Źródło :
Mutation research [Mutat Res] 2020 Apr; Vol. 852, pp. 503162. Date of Electronic Publication: 2020 Feb 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzo(a)pyrene/*toxicity
Carcinogens/*toxicity
Cytochrome P-450 Enzyme System/*genetics
DNA Adducts/*chemistry
Benzo(a)pyrene/chemistry ; Benzo(a)pyrene/metabolism ; Cell Survival/drug effects ; Cytochrome P-450 Enzyme System/deficiency ; DNA Adducts/agonists ; DNA Adducts/metabolism ; DNA Damage ; Dose-Response Relationship, Drug ; Gene Expression ; Gene Knockout Techniques ; Hep G2 Cells ; Humans
Czasopismo naukowe

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