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Wyszukujesz frazę ""DNA Damage"" wg kryterium: Temat


Tytuł:
Cell Type-Specific Patterns in the Accumulation of DNA Damage Following Multifractional Radiation Exposure.
Autorzy:
Akuwudike P; Centre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 10691 Stockholm, Sweden.
Tartas A; Biomedical Physics Division, Faculty of Physics, Institute of Experimental Physics, University of Warsaw, 02-093 Warsaw, Poland.
López-Riego M; Centre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 10691 Stockholm, Sweden.
Toma-Dasu I; Department of Oncology-Pathology, Karolinska Institutet, 17176 Stockholm, Sweden.; Department of Physics, Stockholm University, 10691 Stockholm, Sweden.
Wojcik A; Centre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 10691 Stockholm, Sweden.; Institute of Biology, Jan Kochanowski University, 25-369 Kielce, Poland.
Lundholm L; Centre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 10691 Stockholm, Sweden.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 25; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 25.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
Radiation Exposure*
Dose-Response Relationship, Radiation ; Radiation Tolerance/physiology ; Dose Fractionation, Radiation
Czasopismo naukowe
Tytuł:
Track Structure-Based Simulations on DNA Damage Induced by Diverse Isotopes.
Autorzy:
Kundrát P; Department of Radiation Dosimetry, Nuclear Physics Institute, Czech Academy of Sciences, Na Truhlářce 39/64, 180 00 Prague, Czech Republic.
Friedland W; Institute of Radiation Medicine, Helmholtz Zentrum München, GmbH-German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
Baiocco G; Radiation Biophysics and Radiobiology Group, Physics Department, University of Pavia, 27100 Pavia, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 08; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 08.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
Isotopes*
Monte Carlo Method ; Ions ; DNA
Czasopismo naukowe
Tytuł:
Effect of heat stress on DNA damage: a systematic literature review.
Autorzy:
Habibi P; Department of Occupational Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Ostad SN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Heydari A; Department of Health in Disaster and Emergencies, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Aliebrahimi S; Artificial Intelligence Department, Smart University of Medical Sciences, Tehran, Iran.
Montazeri V; Artificial Intelligence Department, Smart University of Medical Sciences, Tehran, Iran.
Foroushani AR; Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Monazzam MR; Department of Occupational Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Ghazi-Khansari M; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Golbabaei F; Department of Occupational Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. .
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Źródło:
International journal of biometeorology [Int J Biometeorol] 2022 Nov; Vol. 66 (11), pp. 2147-2158. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Systematic Review; Journal Article; Review
MeSH Terms:
DNA Damage*
Heat Stress Disorders*
Humans ; 8-Hydroxy-2'-Deoxyguanosine ; Heat-Shock Response ; Hot Temperature
Czasopismo naukowe
Tytuł:
DNA Damage-Induced RNAPII Degradation and Its Consequences in Gene Expression.
Autorzy:
Muñoz JC; Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE-UBA-CONICET), Ciudad Universitaria, Buenos Aires C1428EHA, Argentina.
Beckerman I; Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE-UBA-CONICET), Ciudad Universitaria, Buenos Aires C1428EHA, Argentina.
Choudhary R; IFOM ETS-The AIRC Institute of Molecular Oncology, Via Adamello, 16, 20139 Milan, Italy.
Bouvier LA; Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE-UBA-CONICET), Ciudad Universitaria, Buenos Aires C1428EHA, Argentina.
Muñoz MJ; Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE-UBA-CONICET), Ciudad Universitaria, Buenos Aires C1428EHA, Argentina.; IFOM ETS-The AIRC Institute of Molecular Oncology, Via Adamello, 16, 20139 Milan, Italy.; Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires C1428EHA, Argentina.
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Źródło:
Genes [Genes (Basel)] 2022 Oct 26; Vol. 13 (11). Date of Electronic Publication: 2022 Oct 26.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Damage*/genetics
RNA Polymerase II*/genetics
RNA Polymerase II*/metabolism
Humans ; DNA Repair/genetics ; Gene Expression ; Ubiquitination/genetics
Czasopismo naukowe
Tytuł:
PRMT7 Inhibitor SGC8158 Enhances Doxorubicin-Induced DNA Damage and Its Cytotoxicity.
Autorzy:
Jeong A; Muscle Physiome Research Center and Drug Information Research Institute, College of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.
Cho Y; Muscle Physiome Research Center and Drug Information Research Institute, College of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.
Cho M; Muscle Physiome Research Center and Drug Information Research Institute, College of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.
Bae GU; Muscle Physiome Research Center and Drug Information Research Institute, College of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.
Song DG; Natural Products Research Institute, KIST Gangneung, Gangneung 25451, Korea.
Kim SN; Natural Products Research Institute, KIST Gangneung, Gangneung 25451, Korea.; Division of Bio-Medical Science and Technology, University of Science and Technology KIST School, Seoul 02792, Korea.
Kim YK; Muscle Physiome Research Center and Drug Information Research Institute, College of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 14; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Protein-Arginine N-Methyltransferases*/genetics
Protein-Arginine N-Methyltransferases*/metabolism
DNA Damage*
RNA, Small Interfering/genetics ; Cell Movement ; Doxorubicin/pharmacology
Czasopismo naukowe
Tytuł:
Ultraviolet B irradiation induces senescence of human corneal endothelial cells in vitro by DNA damage response and oxidative stress.
Autorzy:
Jiang GJ; College of marine life sciences, Ocean university of China, Qingdao, Shandong province 266003, China.
You XG; School of bioscience and technology, Weifang medical university, Weifang, Shandong province 261053, China.
Fan TJ; College of marine life sciences, Ocean university of China, Qingdao, Shandong province 266003, China. Electronic address: .
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Źródło:
Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2022 Oct; Vol. 235, pp. 112568. Date of Electronic Publication: 2022 Sep 15.
Typ publikacji:
Journal Article
MeSH Terms:
Cellular Senescence*/radiation effects
DNA Damage*
Endothelial Cells*/cytology
Endothelial Cells*/radiation effects
Oxidative Stress*
Ultraviolet Rays*/adverse effects
Cells, Cultured ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; Humans ; Reactive Oxygen Species/metabolism ; Transforming Growth Factor beta1/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Tumor Suppressor Protein p53/metabolism ; beta-Galactosidase/metabolism
Czasopismo naukowe
Tytuł:
DNA repair inhibitors and radiotherapy.
Autorzy:
Monge-Cadet J; Radiothérapie, institut universitaire du cancer de Toulouse, 1, avenue Irène-Joliot-Curie, 31100 Toulouse, France. Electronic address: .
Moyal E; Radiothérapie, institut universitaire du cancer de Toulouse, 1, avenue Irène-Joliot-Curie, 31100 Toulouse, France.
Supiot S; Radiothérapie, institut de cancérologie de l'Ouest, boulevard Professeur Jacques-Monod, 44800 Saint-Herblain, France.
Guimas V; Radiothérapie, institut de cancérologie de l'Ouest, boulevard Professeur Jacques-Monod, 44800 Saint-Herblain, France.
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Źródło:
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2022 Oct; Vol. 26 (6-7), pp. 947-954. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
DNA Damage*
DNA Repair*
DNA ; Humans
Czasopismo naukowe
Tytuł:
Critical DNA damaging pathways in tumorigenesis.
Autorzy:
Kloeber JA; Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA; Mayo Clinic Medical Scientist Training Program, Mayo Clinic, Rochester, MN, 55905, USA.
Lou Z; Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. Electronic address: .
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Źródło:
Seminars in cancer biology [Semin Cancer Biol] 2022 Oct; Vol. 85, pp. 164-184. Date of Electronic Publication: 2021 Apr 24.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
DNA Repair*/genetics
DNA Damage*
Humans ; DNA Breaks, Double-Stranded ; Cell Transformation, Neoplastic/metabolism ; DNA ; Genomic Instability ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Determination of potential thresholds for N-ethyl-N-nitrosourea and ethyl methanesulfonate based on a multi-endpoint genotoxicity assessment platform in rats.
Autorzy:
Zhu X; Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China.; West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Huo J; Department of Nutrition and Food Safety, Chongqing Center for Disease Control and Prevention, Chongqing, China.; Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China.
Zeng Z; Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China.; Chengdu Fifth People's Hospital, Chengdu, Sichuan, China.
Liu Y; Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, Sichuan, China.
Li R; Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, Sichuan, China.
Chen Y; Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, Sichuan, China.
Zhang L; Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, Sichuan, China.
Chen J; Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China. .; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, Sichuan, China. .
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Źródło:
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2022 Dec; Vol. 29 (56), pp. 85128-85142. Date of Electronic Publication: 2022 Jul 06.
Typ publikacji:
Journal Article
MeSH Terms:
Ethylnitrosourea*/toxicity
DNA Damage*
Rats ; Animals ; Male ; Ethyl Methanesulfonate/toxicity ; Dose-Response Relationship, Drug ; Rats, Sprague-Dawley ; Micronucleus Tests/methods ; Mutagens/toxicity ; Mutagenicity Tests/methods
Czasopismo naukowe
Tytuł:
The Genotoxicity of Acrylfentanyl, Ocfentanyl and Furanylfentanyl Raises the Concern of Long-Term Consequences.
Autorzy:
Gasperini S; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.
Bilel S; LTTA Center and University Center of Gender Medicine, Department of Translational Medicine, Section of Legal Medicine, University of Ferrara, 44121 Ferrara, Italy.
Cocchi V; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.
Marti M; LTTA Center and University Center of Gender Medicine, Department of Translational Medicine, Section of Legal Medicine, University of Ferrara, 44121 Ferrara, Italy.; Collaborative Center of the National Early Warning System, Department for Anti-Drug Policies, Presidency of the Council of Ministers, 00186 Rome, Italy.
Lenzi M; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.
Hrelia P; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 19; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 19.
Typ publikacji:
Journal Article
MeSH Terms:
Fentanyl*/toxicity
DNA Damage*
Humans ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł:
Translesion Synthesis across the N -Ethyl-deoxyguanosine Adduct by Human PrimPol.
Autorzy:
Boldinova EO; Institute of Molecular Genetics, National Research Center Kurchatov Institute, Kurchatov sq. 2, Moscow 123182, Russia.
Ghodke PP; Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
Sudhakar S; Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
Mishra VK; Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
Manukyan AA; Institute of Molecular Genetics, National Research Center Kurchatov Institute, Kurchatov sq. 2, Moscow 123182, Russia.
Miropolskaya N; Institute of Molecular Genetics, National Research Center Kurchatov Institute, Kurchatov sq. 2, Moscow 123182, Russia.
Pradeepkumar PI; Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
Makarova AV; Institute of Molecular Genetics, National Research Center Kurchatov Institute, Kurchatov sq. 2, Moscow 123182, Russia.
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Źródło:
ACS chemical biology [ACS Chem Biol] 2022 Nov 18; Vol. 17 (11), pp. 3238-3250. Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:
Journal Article
MeSH Terms:
Deoxycytidine Monophosphate*
DNA Damage*
Humans ; Deoxyguanosine/chemistry ; DNA Replication ; DNA-Directed DNA Polymerase/metabolism ; DNA/chemistry ; DNA Adducts ; Nuclear Proteins/metabolism ; DNA Primase/metabolism ; Multifunctional Enzymes/metabolism
Czasopismo naukowe
Tytuł:
Unexpected new insights into DNA clamp loaders: Eukaryotic clamp loaders contain a second DNA site for recessed 5' ends that facilitates repair and signals DNA damage: Eukaryotic clamp loaders contain a second DNA site for recessed 5' ends that facilitates repair and signals DNA damage.
Autorzy:
Li H; Department of Structural Biology, Van Andel Institute, Grand Rapids, Michigan, USA.
O'Donnell M; DNA Replication Laboratory, The Rockefeller University, New York, New York, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.
Kelch B; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
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Źródło:
BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2022 Nov; Vol. 44 (11), pp. e2200154. Date of Electronic Publication: 2022 Sep 18.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
Saccharomyces cerevisiae Proteins*/metabolism
Humans ; Replication Protein C/chemistry ; Replication Protein C/genetics ; Replication Protein C/metabolism ; Proliferating Cell Nuclear Antigen/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; DNA Replication ; DNA/metabolism ; Adenosine Triphosphate/metabolism ; DNA, Circular/metabolism ; Cell Cycle Proteins/metabolism ; DNA-Binding Proteins/metabolism ; Nuclear Proteins/metabolism
Czasopismo naukowe
Tytuł:
Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites.
Autorzy:
Cao Y; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Oh J; Department of Chemistry, Yale University, New Haven, CT 06520, USA.; Institute of Biomolecular Design and Discovery, Yale University, West Haven, CT 06516, USA.
Xue M; Department of Chemistry, Yale University, New Haven, CT 06520, USA.
Huh WJ; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA.
Wang J; Program of Computational Biology and Bioinformatics, Yale University, New Haven, CT 06510, USA.
Gonzalez-Hernandez JA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Rice TA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Martin AL; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Song D; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Crawford JM; Department of Chemistry, Yale University, New Haven, CT 06520, USA.; Institute of Biomolecular Design and Discovery, Yale University, West Haven, CT 06516, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
Herzon SB; Department of Chemistry, Yale University, New Haven, CT 06520, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.
Palm NW; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Oct 28; Vol. 378 (6618), pp. eabm3233. Date of Electronic Publication: 2022 Oct 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/microbiology
DNA Damage*
Gastrointestinal Microbiome*
Inflammatory Bowel Diseases*/microbiology
Morganella morganii*/genetics
Morganella morganii*/isolation & purification
Morganella morganii*/metabolism
Indoles*/metabolism
Mutagens*/metabolism
Animals ; Mice ; Carcinogenesis/genetics ; Humans ; HeLa Cells
Czasopismo naukowe
Tytuł:
Microbial metabolites damage DNA.
Autorzy:
Puschhof J; Microbiome and Cancer Division, German Cancer Research Center, Heidelberg, Germany.
Sears CL; Departments of Medicine and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; TheBloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Oct 28; Vol. 378 (6618), pp. 358-359. Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
Colorectal Neoplasms*/diagnosis
Colorectal Neoplasms*/microbiology
DNA Damage*
Gastrointestinal Microbiome*
Morganella morganii*/metabolism
Mutagens*/metabolism
Humans ; Mice
Czasopismo naukowe
Tytuł:
Assessing the DNA Damaging Effectiveness of Ionizing Radiation Using Plasmid DNA.
Autorzy:
Maayah Y; Department of Physics, San Diego State University, San Diego, CA 92182, USA.
Nusrat H; Odette Cancer Centre, Department of Radiation Oncology, University of Toronto, Toronto, ON M4N 3M5, Canada.
Pang G; Odette Cancer Centre, Department of Radiation Oncology, University of Toronto, Toronto, ON M4N 3M5, Canada.
Tambasco M; Department of Physics, San Diego State University, San Diego, CA 92182, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 18; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 18.
Typ publikacji:
Journal Article
MeSH Terms:
Aluminum*
DNA Damage*
Dose-Response Relationship, Radiation ; Plasmids/genetics ; Radiation, Ionizing ; DNA/genetics
Czasopismo naukowe
Tytuł:
Sirtuin5 protects colorectal cancer from DNA damage by keeping nucleotide availability.
Autorzy:
Wang HL; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chen Y; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Wang YQ; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Tao EW; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Tan J; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Liu QQ; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Li CM; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Tong XM; Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Gao QY; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Hong J; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chen YX; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. .
Fang JY; State Key Laboratory for Oncogenes and Related Genes, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
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Źródło:
Nature communications [Nat Commun] 2022 Oct 17; Vol. 13 (1), pp. 6121. Date of Electronic Publication: 2022 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/metabolism
DNA Damage*
Sirtuins*/genetics
Sirtuins*/metabolism
Humans ; Histone Deacetylases/genetics ; NAD/metabolism ; Nucleosides ; Nucleotides ; Transketolase
Czasopismo naukowe
Tytuł:
Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases.
Autorzy:
Basu AK; Department of Chemistry, The University of Connecticut Storrs, Storrs, Connecticut 06269, United States.
Essigmann JM; Departments of Chemistry, Biological Engineering and Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2022 Oct 17; Vol. 35 (10), pp. 1655-1675. Date of Electronic Publication: 2022 Jul 26.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
DNA Damage*
DNA Repair*
DNA/genetics ; Humans ; Mutagenesis ; Mutation
Czasopismo naukowe
Tytuł:
Complex genomic patterns of abasic sites in mammalian DNA revealed by a high-resolution SSiNGLe-AP method.
Autorzy:
Cai Y; Institute of Genomics, School of Medicine, Huaqiao University, 668 Jimei Road, 361021, Xiamen, China.
Cao H; Institute of Genomics, School of Medicine, Huaqiao University, 668 Jimei Road, 361021, Xiamen, China. .
Wang F; Institute of Genomics, School of Medicine, Huaqiao University, 668 Jimei Road, 361021, Xiamen, China.
Zhang Y; Institute of Genomics, School of Medicine, Huaqiao University, 668 Jimei Road, 361021, Xiamen, China.
Kapranov P; Institute of Genomics, School of Medicine, Huaqiao University, 668 Jimei Road, 361021, Xiamen, China. .
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Źródło:
Nature communications [Nat Commun] 2022 Oct 05; Vol. 13 (1), pp. 5868. Date of Electronic Publication: 2022 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA*/genetics
DNA*/metabolism
DNA Damage*/genetics
Animals ; DNA Repair ; Genomics ; Humans ; Mammals/genetics ; Mice ; Nucleotides/genetics
Czasopismo naukowe
Tytuł:
Doxorubicin induces prolonged DNA damage signal in cells overexpressing DEK isoform-2.
Autorzy:
Özçelik E; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Kalaycı A; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Çelik B; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Avcı A; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Akyol H; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Kılıç İB; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Güzel T; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Çetin M; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Öztürk MT; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Çalışkaner ZO; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Tombaz M; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.
Yoleri D; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
Konu Ö; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.
Kandilci A; Department of Molecular Biology and Genetics, Gebze Technical University, Gebze, Kocaeli, Turkey.
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Źródło:
PloS one [PLoS One] 2022 Oct 03; Vol. 17 (10), pp. e0275476. Date of Electronic Publication: 2022 Oct 03 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Chromosomal Proteins, Non-Histone*/genetics
Chromosomal Proteins, Non-Histone*/metabolism
DNA Damage*
Doxorubicin*/pharmacology
Oncogene Proteins*/genetics
Oncogene Proteins*/metabolism
Poly-ADP-Ribose Binding Proteins*/genetics
Poly-ADP-Ribose Binding Proteins*/metabolism
Amino Acids/genetics ; Humans ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; RNA, Small Interfering
Czasopismo naukowe
Tytuł:
Nuclear RAC1 is a modulator of the doxorubicin-induced DNA damage response.
Autorzy:
Kitzinger R; Institute of Toxicology, Medical Faculty of the Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Fritz G; Institute of Toxicology, Medical Faculty of the Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Henninger C; Institute of Toxicology, Medical Faculty of the Heinrich Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany. Electronic address: .
Pokaż więcej
Źródło:
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2022 Oct; Vol. 1869 (10), pp. 119320. Date of Electronic Publication: 2022 Jul 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Damage*
Fibroblasts*/metabolism
Animals ; Cell Nucleus/metabolism ; Doxorubicin/metabolism ; Doxorubicin/pharmacology ; Mice ; Phosphorylation
Czasopismo naukowe

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