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Tytuł:
Characterization of a Preclinical In Vitro Model Derived from a SMARCA4-Mutated Sinonasal Teratocarcinosarcoma.
Autorzy:
Lorenzo-Guerra SL; Department of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.
Codina-Martínez H; Department of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.
Suárez-Fernández L; Department of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.
Cabal VN; Department of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.
García-Marín R; Department of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.
Riobello C; Department of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.
Vivanco B; Department of Pathology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Blanco-Lorenzo V; Department of Pathology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Sánchez-Fernández P; Department of Otolaryngology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
López F; Department of Otolaryngology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Llorente JL; Department of Otolaryngology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Hermsen MA; Department of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.
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Źródło:
Cells [Cells] 2023 Dec 30; Vol. 13 (1). Date of Electronic Publication: 2023 Dec 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nose Neoplasms*
Teratoma*/genetics
Carcinosarcoma*/genetics
Sarcoma*
Humans ; Cyclin-Dependent Kinase Inhibitor Proteins ; DNA Helicases/genetics ; Nuclear Proteins/genetics ; Transcription Factors/genetics
SCR Disease Name:
Malignant Teratocarcinosarcoma
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dynamics and Conformations of a Full-Length CRESS-DNA Replicase.
Autorzy:
Tarasova E; Department of Chemistry and Biochemistry, City College of New York, New York, NY 10031, USA.
Khayat R; Department of Chemistry and Biochemistry, City College of New York, New York, NY 10031, USA.
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Źródło:
Viruses [Viruses] 2023 Dec 08; Vol. 15 (12). Date of Electronic Publication: 2023 Dec 08.
Typ publikacji:
Journal Article
MeSH Terms:
DNA, Single-Stranded*
Brassicaceae*
Animals ; Swine ; DNA Helicases/genetics ; Hydrolysis ; DNA, Viral/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human RTEL1 Interacts with KPNB1 (Importin β) and NUP153 and Connects Nuclear Import to Nuclear Envelope Stability in S-Phase.
Autorzy:
Schertzer M; Institut Curie, PSL Research University, CNRS, UMR3244, F-75005 Paris, France.; Sorbonne Universités, CNRS, UMR3244, F-75005 Paris, France.
Jullien L; INSERM UMR 1163, Laboratory of Genome Dynamics in the Immune System, Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, F-75015 Paris, France.
Pinto AL; Department of Medical Imaging, Hematology, and Oncology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil.
Calado RT; Department of Medical Imaging, Hematology, and Oncology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil.
Revy P; INSERM UMR 1163, Laboratory of Genome Dynamics in the Immune System, Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, F-75015 Paris, France.
Londoño-Vallejo A; Institut Curie, PSL Research University, CNRS, UMR3244, F-75005 Paris, France.; Sorbonne Universités, CNRS, UMR3244, F-75005 Paris, France.
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Źródło:
Cells [Cells] 2023 Dec 08; Vol. 12 (24). Date of Electronic Publication: 2023 Dec 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nuclear Envelope*/metabolism
beta Karyopherins*/metabolism
Humans ; Active Transport, Cell Nucleus ; Nuclear Pore Complex Proteins/metabolism ; DNA Replication ; DNA Helicases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tazemetostat in the therapy of pediatric INI1-negative malignant rhabdoid tumors.
Autorzy:
Vejmelkova K; Department of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, 62500, Brno, Czechia. .
Pokorna P; Department of Biology, Faculty of Medicine and Central European Institute of Technology, Masaryk University, 62500, Brno, Czechia.
Noskova K; Department of Hospital Pharmacy, University Hospital Brno and Faculty of Medicine, Masaryk University, 62500, Brno, Czechia.; Department of Pharmacology, Faculty of Medicine, Masaryk University, 62500, Brno, Czechia.
Faustmannova A; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Masaryk University, 62500, Brno, Czechia.
Drabova K; Department of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, 62500, Brno, Czechia.
Pavelka Z; Department of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, 62500, Brno, Czechia.
Bajciova V; Department of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, 62500, Brno, Czechia.
Broz M; Department of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, 62500, Brno, Czechia.
Tinka P; Department of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, 62500, Brno, Czechia.
Jezova M; Department of Pathology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, 62500, Czechia.
Palova H; Department of Biology, Faculty of Medicine and Central European Institute of Technology, Masaryk University, 62500, Brno, Czechia.
Kren L; Department of Pathology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, 62500, Czechia.
Valik D; Department of Laboratory Medicine, University Hospital Brno and Department of Laboratory Methods, Faculty of Medicine, Masaryk University, 62500, Brno, Czechia.
Slaby O; Department of Biology, Faculty of Medicine and Central European Institute of Technology, Masaryk University, 62500, Brno, Czechia.
Sterba J; Department of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, 62500, Brno, Czechia.
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 07; Vol. 13 (1), pp. 21623. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Rhabdoid Tumor*/drug therapy
Rhabdoid Tumor*/pathology
Teratoma*/pathology
Central Nervous System Neoplasms*/pathology
Humans ; Child ; Female ; Infant ; Child, Preschool ; Neoplasm Recurrence, Local/drug therapy ; SMARCB1 Protein ; DNA Helicases ; Nuclear Proteins ; Transcription Factors
SCR Disease Name:
Typical Teratoid Rhabdoid Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
RTEL1 gene polymorphisms and neuroblastoma risk in Chinese children.
Autorzy:
Zhang T; Department of Clinical Laboratory, The Affiliated Wenling Hospital of Wenzhou Medical University, Taizhou, 317500, Zhejiang, China.
Zhou C; Department of Pathology, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, 210008, Jiangsu, China.
Guo J; Department of Clinical Laboratory, The Affiliated Wenling Hospital of Wenzhou Medical University, Taizhou, 317500, Zhejiang, China.
Chang J; Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, 9 Jinsui Road, Guangzhou, 510623, Guangdong, China.
Wu H; Department of Pathology, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, 210008, Jiangsu, China. .
He J; Department of Clinical Laboratory, The Affiliated Wenling Hospital of Wenzhou Medical University, Taizhou, 317500, Zhejiang, China. .; Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, 9 Jinsui Road, Guangzhou, 510623, Guangdong, China. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Nov 24; Vol. 23 (1), pp. 1145. Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:
Journal Article
MeSH Terms:
Genetic Predisposition to Disease*
Neuroblastoma*/genetics
Neuroblastoma*/pathology
Male ; Female ; Humans ; Child ; East Asian People ; Genotype ; Polymorphism, Single Nucleotide ; Case-Control Studies ; DNA Helicases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
DNA damage repair-related gene signature for identifying the immune status and predicting the prognosis of hepatocellular carcinoma.
Autorzy:
Lu Y; Department of Plastic Surgery, Shandong University of Traditional Chinese Medicine, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qian Foshan Hospital, Jingshi Road, Jinan, 250014, Shandong, China.
Wang S; Department of Medical Ultrasound, Shandong Medicine and Health Key Laboratory of Abdominal Medical Imaging, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qian Foshan Hospital, Shandong First Medical University, No. 16766, Jingshi Road, Jinan, 250014, Shandong, China.
Chi T; Department of Acupuncture and Rehabilitation, The Affiliated Qingdao Hai Ci Hospital of Qingdao University (West Hospital Area), Qingdao, 266000, Shandong, China.
Zhao Y; Department of Medical Ultrasound, Shandong Medicine and Health Key Laboratory of Abdominal Medical Imaging, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qian Foshan Hospital, Shandong First Medical University, No. 16766, Jingshi Road, Jinan, 250014, Shandong, China.
Guo H; Department of Medical Ultrasound, Shandong Medicine and Health Key Laboratory of Abdominal Medical Imaging, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qian Foshan Hospital, Jining Medical College, No. 16766, Jingshi Road, Jinan, 250014, Shandong, China.
Wang H; Department of Medical Ultrasound, Shandong Medicine and Health Key Laboratory of Abdominal Medical Imaging, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qian Foshan Hospital, Shandong First Medical University, No. 16766, Jingshi Road, Jinan, 250014, Shandong, China.
Feng L; Department of Medical Ultrasound, Shandong Medicine and Health Key Laboratory of Abdominal Medical Imaging, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qian Foshan Hospital, Shandong First Medical University, No. 16766, Jingshi Road, Jinan, 250014, Shandong, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 03; Vol. 13 (1), pp. 18978. Date of Electronic Publication: 2023 Nov 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Liver Neoplasms*/genetics
Humans ; Prognosis ; DNA Damage ; RNA, Messenger/genetics ; ATPases Associated with Diverse Cellular Activities ; Carrier Proteins ; DNA Helicases/genetics ; DNA-Binding Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice.
Autorzy:
Göbel C; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, 20251, Germany.; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, Building N63 (LIV), Hamburg, D-20251, Germany.
Godbole S; Center for Molecular Neurobiology, Falkenried 94, Hamburg, 20251, Germany.
Schoof M; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, 20251, Germany.; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, Building N63 (LIV), Hamburg, D-20251, Germany.
Holdhof D; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, 20251, Germany.; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, Building N63 (LIV), Hamburg, D-20251, Germany.
Kresbach C; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, 20251, Germany.; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, Building N63 (LIV), Hamburg, D-20251, Germany.; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, 20251, Germany.
Loose C; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, 20251, Germany.; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, Building N63 (LIV), Hamburg, D-20251, Germany.
Neumann J; Center for Molecular Neurobiology, Falkenried 94, Hamburg, 20251, Germany.; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, 20251, Germany.
Schüller U; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, 20251, Germany. .; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, Building N63 (LIV), Hamburg, D-20251, Germany. .; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, 20251, Germany. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Nov 02; Vol. 11 (1), pp. 174. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Neoplasms*/genetics
Cerebellar Neoplasms*/metabolism
Medulloblastoma*/metabolism
Animals ; Humans ; Mice ; DNA Helicases/genetics ; Hedgehog Proteins/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Transcription Factors/genetics ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prognostic and predictive impact of molecular tumor burden index in non-small cell lung cancer patients.
Autorzy:
Yang F; Department of Medical Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Tang M; Department of Medical Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Cui L; Geneplus-Beijing Institute, Beijing, People's Republic of China.
Bai J; Geneplus-Beijing Institute, Beijing, People's Republic of China.
Yu J; Department of Medical Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Gao J; Department of Medical Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Nie X; Department of Medical Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Li X; Department of Medical Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Xia X; Geneplus-Beijing Institute, Beijing, People's Republic of China.
Yi X; Geneplus-Beijing Institute, Beijing, People's Republic of China.
Zhang P; Department of Medical Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Li L; Department of Medical Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
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Źródło:
Thoracic cancer [Thorac Cancer] 2023 Nov; Vol. 14 (31), pp. 3097-3107. Date of Electronic Publication: 2023 Sep 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/pathology
Humans ; Prognosis ; Tumor Burden ; Biomarkers, Tumor ; DNA Helicases ; Nuclear Proteins ; Transcription Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transcriptional targets of senataxin and E2 promoter binding factors are associated with neuro-degenerative pathways during increased autophagic flux.
Autorzy:
Casey AE; Computational and Systems Biology Program, Precision Medicine Theme, South Australian Health and Medical Research Institute, North Terrace, Adelaide, SA, 5000, Australia. .; Australian Centre for Precision Health, Cancer Research Institute, University of South Australia, Adelaide, Australia. .
Liu W; Dame Roma Mitchell Cancer Research Laboratories, Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia.
Hein LK; Lysosomal Health in Ageing, Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute, Adelaide, Australia.
Sargeant TJ; Lysosomal Health in Ageing, Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute, Adelaide, Australia.
Pederson SM; Dame Roma Mitchell Cancer Research Laboratories, Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia.
Mäkinen VP; Computational and Systems Biology Program, Precision Medicine Theme, South Australian Health and Medical Research Institute, North Terrace, Adelaide, SA, 5000, Australia.; Australian Centre for Precision Health, Cancer Research Institute, University of South Australia, Adelaide, Australia.; Computational Medicine, Faculty of Medicine, University of Oulu, Oulu, Finland.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 21; Vol. 12 (1), pp. 17665. Date of Electronic Publication: 2022 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Helicases*/genetics
Multifunctional Enzymes*/genetics
RNA Helicases*/genetics
Humans ; Amino Acids ; Autophagy/genetics ; HEK293 Cells ; TOR Serine-Threonine Kinases/metabolism ; Transcription Factors/genetics ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes.
Autorzy:
Yang E; Molecular Biology Institute, University of California, Los Angeles, California, United States of America.; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, California, United States of America.
Huang S; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, California, United States of America.
Jami-Alahmadi Y; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, United States of America.
McInerney GM; Department of Microbiology, Tumor, and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Wohlschlegel JA; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, United States of America.
Li MMH; Molecular Biology Institute, University of California, Los Angeles, California, United States of America.; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, California, United States of America.; AIDS Institute, David Geffen School of Medicine, University of California, Los Angeles, California, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2022 Sep 06; Vol. 18 (9), pp. e1010743. Date of Electronic Publication: 2022 Sep 06 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Antiviral Agents*/metabolism
DNA Helicases*/metabolism
Interferons/metabolism ; Nucleosides/metabolism ; Poly-ADP-Ribose Binding Proteins/metabolism ; RNA Helicases/metabolism ; RNA Recognition Motif Proteins/metabolism ; Tripartite Motif Proteins/genetics ; Tripartite Motif Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitination ; Ubiquitins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chl1, an ATP-Dependent DNA Helicase, Inhibits DNA:RNA Hybrids Formation at DSB Sites to Maintain Genome Stability in S. pombe .
Autorzy:
He D; State Key Laboratory of Biobased Material and Green Papermaking, School of Bioengineering, Qilu University of Technology, Jinan 250353, China.; Key Laboratory of Shandong Microbial Engineering, Shandong Academy of Sciences, Qilu University of Technology, Jinan 250353, China.
Du Z; State Key Laboratory of Biobased Material and Green Papermaking, School of Bioengineering, Qilu University of Technology, Jinan 250353, China.; Key Laboratory of Shandong Microbial Engineering, Shandong Academy of Sciences, Qilu University of Technology, Jinan 250353, China.
Xu H; State Key Laboratory of Biobased Material and Green Papermaking, School of Bioengineering, Qilu University of Technology, Jinan 250353, China.; Key Laboratory of Shandong Microbial Engineering, Shandong Academy of Sciences, Qilu University of Technology, Jinan 250353, China.
Bao X; State Key Laboratory of Biobased Material and Green Papermaking, School of Bioengineering, Qilu University of Technology, Jinan 250353, China.; Key Laboratory of Shandong Microbial Engineering, Shandong Academy of Sciences, Qilu University of Technology, Jinan 250353, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 14; Vol. 23 (12). Date of Electronic Publication: 2022 Jun 14.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Helicases*/genetics
DNA Helicases*/metabolism
Schizosaccharomyces*/metabolism
Cell Adhesion Molecules/metabolism ; DEAD-box RNA Helicases/genetics ; DEAD-box RNA Helicases/metabolism ; DNA/metabolism ; DNA Breaks, Double-Stranded ; DNA End-Joining Repair ; DNA Repair ; Genomic Instability ; Humans ; RNA/metabolism ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BRG1 is a biomarker of hypertrophic cardiomyopathy in human heart specimens.
Autorzy:
Scherba JC; Department of Biomedical Engineering, Duke University, Durham, NC, 27710, USA.
Halushka MK; Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, 21287, USA.
Andersen ND; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC, 27710, USA.
Maleszewski JJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.
Landstrom AP; Division of Pediatric Cardiology, Department of Pediatrics, Duke University Medical Center, Durham, NC, 27710, USA.
Bursac N; Department of Biomedical Engineering, Duke University, Durham, NC, 27710, USA.
Glass C; Department of Pathology, Duke University Medical Center, 217AM Davison Bldg, 40 Duke Medicine Circle, Box 3712 DUHS, Durham, NC, 27710, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 May 17; Vol. 12 (1), pp. 7996. Date of Electronic Publication: 2022 May 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cardiomyopathy, Hypertrophic*/genetics
Cardiomyopathy, Hypertrophic*/metabolism
Cardiomyopathy, Hypertrophic*/pathology
DNA Helicases*/genetics
DNA Helicases*/metabolism
Induced Pluripotent Stem Cells*/metabolism
Nuclear Proteins*/genetics
Nuclear Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Animals ; Biomarkers/metabolism ; Humans ; Mice ; Mutation ; Myosin Heavy Chains/genetics ; Myosin Heavy Chains/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Endometrial cancer (EC) derived G3BP1 overexpression and mutant promote EC tumorigenesis and metastasis via SPOP/ERα axis.
Autorzy:
Ge Y; Department of Radiotherapy and Chemotherapy, The First Hospital of Ningbo University, Ningbo University, Ningbo, 315010, China.; The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China.; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Health Science Center, Medical School of Ningbo University, Ningbo University, Ningbo, 315211, Zhejiang, China.
Jin J; The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China.
Chen G; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Health Science Center, Medical School of Ningbo University, Ningbo University, Ningbo, 315211, Zhejiang, China.
Li J; Department of Radiotherapy and Chemotherapy, The First Hospital of Ningbo University, Ningbo University, Ningbo, 315010, China. .; The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China. .
Ye M; Department of Radiotherapy and Chemotherapy, The First Hospital of Ningbo University, Ningbo University, Ningbo, 315010, China. .; The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China. .
Jin X; Department of Radiotherapy and Chemotherapy, The First Hospital of Ningbo University, Ningbo University, Ningbo, 315010, China. .; The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China. .; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Health Science Center, Medical School of Ningbo University, Ningbo University, Ningbo, 315211, Zhejiang, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2023 Oct 30; Vol. 21 (1), pp. 303. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endometrial Neoplasms*/metabolism
Estrogen Receptor alpha*/metabolism
Female ; Humans ; Male ; Cell Transformation, Neoplastic ; DNA Helicases/genetics ; DNA Helicases/metabolism ; Fulvestrant ; Poly-ADP-Ribose Binding Proteins/genetics ; Poly-ADP-Ribose Binding Proteins/metabolism ; RNA Helicases/genetics ; RNA Helicases/metabolism ; RNA Recognition Motif Proteins/genetics ; RNA Recognition Motif Proteins/metabolism ; Ubiquitination
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The plant organellar primase-helicase directs template recognition and primosome assembly via its zinc finger domain.
Autorzy:
Peralta-Castro A; Langebio-Cinvestav Sede Irapuato, Km. 9.6 Libramiento Norte Carretera. Irapuato-León, 36821, Irapuato Guanajuato, Mexico.
Cordoba-Andrade F; Langebio-Cinvestav Sede Irapuato, Km. 9.6 Libramiento Norte Carretera. Irapuato-León, 36821, Irapuato Guanajuato, Mexico.
Díaz-Quezada C; Langebio-Cinvestav Sede Irapuato, Km. 9.6 Libramiento Norte Carretera. Irapuato-León, 36821, Irapuato Guanajuato, Mexico.
Sotelo-Mundo R; Laboratorio de Estructura Biomolecular, Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas Núm. 46, Ejido a La Victoria, 83304, Hermosillo, Sonora, Mexico.
Winkler R; Langebio-Cinvestav Sede Irapuato, Km. 9.6 Libramiento Norte Carretera. Irapuato-León, 36821, Irapuato Guanajuato, Mexico.
Brieba LG; Langebio-Cinvestav Sede Irapuato, Km. 9.6 Libramiento Norte Carretera. Irapuato-León, 36821, Irapuato Guanajuato, Mexico. .
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Źródło:
BMC plant biology [BMC Plant Biol] 2023 Oct 06; Vol. 23 (1), pp. 467. Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Primase*/genetics
DNA Primase*/chemistry
DNA Primase*/metabolism
Arabidopsis*/metabolism
Animals ; DNA Helicases/chemistry ; DNA Helicases/genetics ; DNA Helicases/metabolism ; DNA-Directed DNA Polymerase/genetics ; DNA-Directed DNA Polymerase/metabolism ; Mitochondria/metabolism ; Zinc Fingers ; Ribonucleotides ; DNA Replication ; Bacteriophage T7/genetics
Czasopismo naukowe
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Tytuł:
Exploring the G-quadruplex binding and unwinding activity of the bacterial FeS helicase DinG.
Autorzy:
De Piante, Elisa (AUTHOR)
D'Aria, Federica (AUTHOR)
Napolitano, Luisa M. R. (AUTHOR)
Amato, Jussara (AUTHOR)
Pirrello, Simone (AUTHOR)
Onesti, Silvia (AUTHOR)
Giancola, Concetta (AUTHOR)
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Źródło:
Scientific Reports. 8/3/2023, Vol. 13 Issue 1, p1-11. 11p.
Czasopismo naukowe
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Tytuł:
TT-pocket/HIRAN: binding to 3'-terminus of DNA for recognition and processing of stalled replication forks.
Autorzy:
Masai H; Department of Basic Medical Sciences, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.
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Źródło:
Journal of biochemistry [J Biochem] 2022 Jul 25; Vol. 172 (2), pp. 57-60.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Helicases*/metabolism
DNA Replication*
DNA/metabolism ; DNA-Binding Proteins/metabolism ; Eukaryotic Cells/metabolism
Czasopismo naukowe
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Tytuł:
The increase in cell death rates in caloric restricted cells of the yeast helicase mutant rrm3 is Sir complex dependent.
Autorzy:
Ivessa AS; Department of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Rutgers Biomedical and Health Sciences, 185 South Orange Avenue, Newark, NJ, 07101-1709, USA. .
Singh S; Pathology and Laboratory Medicine/Flow Cytometry and Immunology Core Laboratory, Rutgers New Jersey Medical School, Rutgers Biomedical and Health Sciences, 185 South Orange Avenue, Newark, NJ, 07101-1709, USA.
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 19; Vol. 13 (1), pp. 17832. Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Caloric Restriction ; DNA Helicases/genetics ; Genomic Instability ; Glucose/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity.
Autorzy:
Bennett CL; Departments of Pathology, Laboratory Medicine, Neurology, and Biological Chemistry, UCI Center for Neurotherapeutics, University of California Irvine School of Medicine, Irvine, CA, 92697, USA.; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.
Dastidar S; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Center for Molecular Neurosciences, Kasturba Medical College, Manipal, 576104, India.
Arnold FJ; Departments of Pathology, Laboratory Medicine, Neurology, and Biological Chemistry, UCI Center for Neurotherapeutics, University of California Irvine School of Medicine, Irvine, CA, 92697, USA.
McKinstry SU; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.
Stockford C; Departments of Pathology, Laboratory Medicine, Neurology, and Biological Chemistry, UCI Center for Neurotherapeutics, University of California Irvine School of Medicine, Irvine, CA, 92697, USA.
Freibaum BD; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Sopher BL; Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, WA, 98195, USA.
Wu M; Department of Pharmacology, University of California, San Diego, La Jolla, CA, 92093, USA.
Seidner G; Department of Pharmacology, University of California, San Diego, La Jolla, CA, 92093, USA.
Joiner W; Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, WA, 98195, USA.
Taylor JP; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, 20815, USA.
West RJH; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, S10 2HQ, UK. .; Neuroscience Institute, University of Sheffield, Sheffield, S10 2TN, UK. .
La Spada AR; Departments of Pathology, Laboratory Medicine, Neurology, and Biological Chemistry, UCI Center for Neurotherapeutics, University of California Irvine School of Medicine, Irvine, CA, 92697, USA. .; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA. .; Department of Neurobiology and Behavior, University of California Irvine School of Biosciences, Irvine, CA, 92697, USA. .; UCI Center for Neurotherapeutics, University of California Irvine, Irvine, CA, 92697, USA. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Oct 17; Vol. 11 (1), pp. 164. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Amyotrophic Lateral Sclerosis*/metabolism
Frontotemporal Dementia*/genetics
Humans ; Animals ; Dipeptides/genetics ; C9orf72 Protein/genetics ; C9orf72 Protein/metabolism ; Arginine/genetics ; Arginine/metabolism ; HEK293 Cells ; Motor Neurons/metabolism ; Drosophila/metabolism ; RNA/metabolism ; DNA Repeat Expansion/genetics ; DNA Helicases/genetics ; RNA Helicases/genetics ; Multifunctional Enzymes/genetics
SCR Disease Name:
Amyotrophic lateral sclerosis 1
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
DDX52 gene expression in LUAD tissues indicates potential as a prognostic biomarker and therapeutic target.
Autorzy:
Xu M; Department of Thoracic Surgery, Affiliated Hospital of Nantong University, 20 Xisi Street, Nantong, 226001, China.
Yang M; Department of Thoracic Surgery, Affiliated Hospital of Nantong University, 20 Xisi Street, Nantong, 226001, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 13; Vol. 13 (1), pp. 17434. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung*
Adenocarcinoma*
Lung Neoplasms*
Humans ; Prognosis ; RNA Helicases ; DNA Helicases ; Gene Expression ; Biomarkers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Switch/Sucrose Non-Fermentable Complex-Deficient Rhabdoid Carcinoma of Stomach: A Rare Case Report and Literature Review.
Autorzy:
Chen M; Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yao X; Department of Hepatopancreatobiliary Surgery, Huzhou Central Hospital, Huzhou, China.
Ping J; Department of Pathology, Huzhou Central Hospital, Huzhou, China.
Shen H; Department of Gastrointestinal Surgery, Huzhou Central Hospital, Huzhou, China.
Wei Y; Department of Gastrointestinal Surgery, Huzhou Central Hospital, Huzhou, China.
Wang WL; Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
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Źródło:
International journal of surgical pathology [Int J Surg Pathol] 2023 Oct; Vol. 31 (7), pp. 1364-1374. Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:
Review; Case Reports; Journal Article
MeSH Terms:
Carcinoma*/pathology
Stomach Neoplasms*/diagnosis
Stomach Neoplasms*/genetics
Rhabdoid Tumor*/diagnosis
Rhabdoid Tumor*/genetics
Adult ; Humans ; Male ; Aged ; Cell Differentiation ; Biomarkers, Tumor/metabolism ; DNA Helicases ; Nuclear Proteins ; Transcription Factors/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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