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Tytuł:
Integrated study of systemic and local airway transcriptomes in asthma reveals causal mediation of systemic effects by airway key drivers.
Autorzy:
Zhang L; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA.
Chun Y; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA.
Irizar H; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA.
Arditi Z; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA.
Grishina G; Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA.
Grishin A; Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA.
Vicencio A; Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA.
Bunyavanich S; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA. .; Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA. .
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Źródło:
Genome medicine [Genome Med] 2023 Sep 20; Vol. 15 (1), pp. 71. Date of Electronic Publication: 2023 Sep 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Leukocytes, Mononuclear*
Asthma*/genetics
Female ; Humans ; Adolescent ; Male ; Transcriptome ; Bayes Theorem ; DNA Helicases ; Poly-ADP-Ribose Binding Proteins ; RNA Helicases ; RNA Recognition Motif Proteins
Czasopismo naukowe
Tytuł:
ERCC6L facilitates the onset of mammary neoplasia and promotes the high malignance of breast cancer by accelerating the cell cycle.
Autorzy:
Yang H; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.
Zhen X; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.
Yang Y; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.
Zhang Y; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.
Zhang S; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.
Hao Y; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.
Du G; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.
Wang H; Department of Pancreatic Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, 300060, China.
Zhang B; Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, 100021, China.
Li W; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China. .; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. .
Wang J; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China. .; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Sep 04; Vol. 42 (1), pp. 227. Date of Electronic Publication: 2023 Sep 04.
Typ publikacji:
Journal Article
MeSH Terms:
Mammary Neoplasms, Animal*
Triple Negative Breast Neoplasms*
Female ; Animals ; Mice ; Humans ; Cell Cycle ; Mitosis ; Carcinogenesis ; Cell Transformation, Neoplastic/genetics ; Kinesins ; DNA Helicases
Czasopismo naukowe
Tytuł:
Deletion of the chd7 Hinders Oligodendrocyte Progenitor Cell Development and Myelination in Zebrafish.
Autorzy:
Shi L; Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Wang Z; Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Li Y; Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Song Z; Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Yin W; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.
Hu B; Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 31; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 31.
Typ publikacji:
Journal Article
MeSH Terms:
CHARGE Syndrome*/genetics
Oligodendrocyte Precursor Cells*
Animals ; Cell Differentiation/genetics ; DNA Helicases/genetics ; Oligodendroglia ; Zebrafish/genetics
Czasopismo naukowe
Tytuł:
SARS-CoV-2 nucleocapsid protein inhibits the PKR-mediated integrated stress response through RNA-binding domain N2b.
Autorzy:
Aloise C; Virology Section, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Schipper JG; Virology Section, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
van Vliet A; Virology Section, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Oymans J; Virology Section, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Donselaar T; Virology Section, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Hurdiss DL; Virology Section, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
de Groot RJ; Virology Section, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
van Kuppeveld FJM; Virology Section, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Aug 22; Vol. 19 (8), pp. e1011582. Date of Electronic Publication: 2023 Aug 22 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*
Humans ; DNA Helicases ; Poly-ADP-Ribose Binding Proteins ; RNA Helicases ; RNA Recognition Motif Proteins/genetics ; RNA-Binding Motifs ; Encephalomyocarditis virus
Czasopismo naukowe
Tytuł:
Downregulation of AHNAK2 inhibits cell cycle of lung adenocarcinoma cells by interacting with RUVBL1.
Autorzy:
Li X; Beijing Chaoyang Hospital, Beijing, China.
Li H; Thoracic Surgery, Beijing Chao-yang Hospital, Beijing, China.
Shao MM; Beijing Chao-Yang Hospital Capital Medical University, Beijing, China.
Miao J; Department of Thoracic Surgery, Beijing Chao-Yang Hospital Affiliated Capital Medical University, Beijing, China.
Fu Y; Thoracic Surgery, Beijing Chao-yang Hospital, Beijing, China.
Hu B; Department of Thoracic Surgery, Beijing Chao-Yang Hospital Affiliated Capital Medical University, Beijing, China.
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Źródło:
Thoracic cancer [Thorac Cancer] 2023 Aug; Vol. 14 (22), pp. 2093-2104. Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung*/pathology
Lung Neoplasms*/pathology
Humans ; ATPases Associated with Diverse Cellular Activities/genetics ; ATPases Associated with Diverse Cellular Activities/metabolism ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; DNA Helicases/genetics ; Down-Regulation
Czasopismo naukowe
Tytuł:
Knockdown of long non‑coding RNA DDX11‑AS1 inhibits the proliferation, migration and paclitaxel resistance of breast cancer cells by upregulating microRNA‑497 expression.
Autorzy:
Liang M; Department of Pathology, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310005, P.R. China.
Zhu B; Department of Infectious Diseases, The First Affiliated Hospital of Jinan University, Guangdong, Guangzhou 510632, P.R. China.
Wang M; Emergency Department, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310005, P.R. China.
Jin J; Department of Pathology, Cancer Hospital of the University of Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2022 Apr; Vol. 25 (4). Date of Electronic Publication: 2022 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms/*genetics
DEAD-box RNA Helicases/*genetics
DNA Helicases/*genetics
Drug Resistance, Neoplasm/*genetics
MicroRNAs/*genetics
RNA, Long Noncoding/*genetics
Antigens, CD/metabolism ; Cadherins/metabolism ; Cell Line ; Cell Movement/genetics ; Cell Proliferation/genetics ; DEAD-box RNA Helicases/metabolism ; DNA Helicases/metabolism ; Humans ; MicroRNAs/metabolism ; Paclitaxel/pharmacology ; RNA, Long Noncoding/metabolism ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł:
OTUD6A promotes prostate tumorigenesis via deubiquitinating Brg1 and AR.
Autorzy:
Fu X; Key Laboratory of Systems Biomedicine (Ministry of Education) and Collaborative Innovation Center of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China.
Zhao J; Department of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai, 200032, China.
Yu G; Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Zhang X; Department of Urology, Shanghai Changhai Hospital, Shanghai, 200433, China.
Sun J; Department of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai, 200032, China.
Li L; Key Laboratory of Systems Biomedicine (Ministry of Education) and Collaborative Innovation Center of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China.
Yin J; Key Laboratory of Systems Biomedicine (Ministry of Education) and Collaborative Innovation Center of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China.
Niu Y; Key Laboratory of Systems Biomedicine (Ministry of Education) and Collaborative Innovation Center of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China.
Ren S; Department of Urology, Shanghai Changhai Hospital, Shanghai, 200433, China.
Zhu Y; Department of Urology, Shanghai Changhai Hospital, Shanghai, 200433, China. .
Xu B; Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. .
Huang L; Key Laboratory of Systems Biomedicine (Ministry of Education) and Collaborative Innovation Center of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China. .
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Źródło:
Communications biology [Commun Biol] 2022 Mar 01; Vol. 5 (1), pp. 182. Date of Electronic Publication: 2022 Mar 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Helicases*/metabolism
Nuclear Proteins*/genetics
Nuclear Proteins*/metabolism
Ovarian Neoplasms*/pathology
Prostatic Neoplasms*/pathology
Receptors, Androgen*/metabolism
Transcription Factors*/metabolism
Animals ; Cell Transformation, Neoplastic ; Deubiquitinating Enzymes/metabolism ; Female ; Heterografts ; Humans ; Male ; Mice ; Prostate/pathology ; Repressor Proteins/metabolism ; Ubiquitination
Czasopismo naukowe
Tytuł:
DNA Polymerase-Parental DNA Interaction Is Essential for Helicase-Polymerase Coupling during Bacteriophage T7 DNA Replication.
Autorzy:
Lo CY; Department of BioSciences, Rice University, Houston, TX 77005, USA.
Gao Y; Department of BioSciences, Rice University, Houston, TX 77005, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 25; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Helicases/*metabolism
DNA Replication/*genetics
DNA-Directed DNA Polymerase/*metabolism
Bacteriophage T7/enzymology ; Bacteriophage T7/metabolism ; DNA Helicases/physiology ; DNA Replication/physiology ; DNA, Viral/metabolism ; DNA-Directed DNA Polymerase/physiology ; Viral Proteins/metabolism
Czasopismo naukowe
Tytuł:
Identification of the nuclear localization signal in the Saccharomyces cerevisiae Pif1 DNA helicase.
Autorzy:
Lee RS; Department of Biology, University of Iowa, Iowa City, Iowa, United States of America.
Geronimo CL; Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America.
Liu L; Department of Biology, University of Iowa, Iowa City, Iowa, United States of America.
Twarowski JM; Department of Biology, University of Iowa, Iowa City, Iowa, United States of America.
Malkova A; Department of Biology, University of Iowa, Iowa City, Iowa, United States of America.
Zakian VA; Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2023 Jul 24; Vol. 19 (7), pp. e1010853. Date of Electronic Publication: 2023 Jul 24 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins*/metabolism
DNA Replication ; Nuclear Localization Signals/genetics ; Nuclear Localization Signals/metabolism ; DNA Helicases/genetics ; DNA Helicases/metabolism
Czasopismo naukowe
Tytuł:
A proteomics study identifying interactors of the FSHD2 gene product SMCHD1 reveals RUVBL1-dependent DUX4 repression.
Autorzy:
Goossens R; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Tihaya MS; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
van den Heuvel A; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Tabot-Ndip K; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Willemsen IM; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Tapscott SJ; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, USA.
González-Prieto R; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Chang JG; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Vertegaal ACO; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Balog J; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. .
van der Maarel SM; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. S.M.van_der_.
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Źródło:
Scientific reports [Sci Rep] 2021 Dec 08; Vol. 11 (1), pp. 23642. Date of Electronic Publication: 2021 Dec 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
ATPases Associated with Diverse Cellular Activities/*genetics
Carrier Proteins/*genetics
Chromosomal Proteins, Non-Histone/*genetics
DNA Helicases/*genetics
Homeodomain Proteins/*genetics
Muscular Dystrophy, Facioscapulohumeral/*genetics
Proteomics/*methods
ATPases Associated with Diverse Cellular Activities/metabolism ; Carrier Proteins/metabolism ; Cell Line, Tumor ; Chromosomal Proteins, Non-Histone/metabolism ; DNA Helicases/metabolism ; Gene Expression Regulation, Developmental ; HEK293 Cells ; Homeodomain Proteins/metabolism ; Humans ; Protein Binding
Czasopismo naukowe
Tytuł:
SUMOylated Senataxin functions in genome stability, RNA degradation, and stress granule disassembly, and is linked with inherited ataxia and motor neuron disease.
Autorzy:
Bennett CL; School of Life Sciences, University of Lincoln, Lincoln, UK.
La Spada AR; Departments of Pathology & Laboratory Medicine, Neurology, and Biological Chemistry, and UCI Institute for Neurotherapeutics, University of California, Irvine, Irvine, California, USA.
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Źródło:
Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2021 Dec; Vol. 9 (12), pp. e1745. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:
Genomic Instability*
RNA Stability*
Ataxia/*etiology
Ataxia/*metabolism
DNA Helicases/*metabolism
Motor Neuron Disease/*etiology
Motor Neuron Disease/*metabolism
Multifunctional Enzymes/*metabolism
RNA Helicases/*metabolism
Stress Granules/*metabolism
Animals ; Ataxia/diagnosis ; Biomarkers ; DNA Helicases/genetics ; DNA-Directed DNA Polymerase/metabolism ; Disease Susceptibility ; Exosomes/metabolism ; Gene Expression Regulation ; Genetic Predisposition to Disease ; Humans ; Multifunctional Enzymes/genetics ; Mutation ; Neurodegenerative Diseases/diagnosis ; Neurodegenerative Diseases/etiology ; Neurodegenerative Diseases/metabolism ; RNA Helicases/genetics ; RNA Polymerase II/metabolism ; S Phase ; S Phase Cell Cycle Checkpoints ; Sumoylation
Czasopismo naukowe
Tytuł:
ESS2 controls prostate cancer progression through recruitment of chromodomain helicase DNA binding protein 1.
Autorzy:
Takahashi, Sayuri (AUTHOR)
Takada, Ichiro (AUTHOR)
Hashimoto, Kenichi (AUTHOR)
Yokoyama, Atsushi (AUTHOR)
Nakagawa, Tohru (AUTHOR)
Makishima, Makoto (AUTHOR)
Kume, Haruki (AUTHOR)
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Źródło:
Scientific Reports. 7/31/2023, Vol. 13 Issue 1, p1-16. 16p.
Czasopismo naukowe
Tytuł:
Apis mellifera Solinvivirus-1, a Novel Honey Bee Virus That Remained Undetected for over a Decade, Is Widespread in the USA.
Autorzy:
Ryabov, Eugene V. (AUTHOR)
Nearman, Anthony J. (AUTHOR)
Nessa, Ashrafun (AUTHOR)
Grubbs, Kyle (AUTHOR)
Sallmann, Benjamin (AUTHOR)
Fahey, Rachel (AUTHOR)
Wilson, Mikayla E. (AUTHOR)
Rennich, Karen D. (AUTHOR)
Steinhauer, Nathalie (AUTHOR)
Fauvel, Anne Marie (AUTHOR)
Chen, Yanping (AUTHOR)
Evans, Jay D. (AUTHOR)
vanEngelsdorp, Dennis (AUTHOR)
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Źródło:
Viruses (1999-4915). Jul2023, Vol. 15 Issue 7, p1597. 13p.
Czasopismo naukowe
Tytuł:
Neuroblastoma Cells Depend on CSB for Faithful Execution of Cytokinesis and Survival.
Autorzy:
Paccosi E; Unit of Molecular Genetics of Aging, Department of Ecology and Biology, University of Tuscia, 01100 Viterbo, Italy.
Costantino M; Unit of Molecular Genetics of Aging, Department of Ecology and Biology, University of Tuscia, 01100 Viterbo, Italy.
Balzerano A; Unit of Molecular Genetics of Aging, Department of Ecology and Biology, University of Tuscia, 01100 Viterbo, Italy.
Filippi S; Unit of Molecular Genetics of Aging, Department of Ecology and Biology, University of Tuscia, 01100 Viterbo, Italy.
Brancorsini S; Unit of Molecular Pathology, Department of Experimental Medicine, Section of Terni, University of Perugia, 06100 Perugia, Italy.
Proietti-De-Santis L; Unit of Molecular Genetics of Aging, Department of Ecology and Biology, University of Tuscia, 01100 Viterbo, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 17; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 17.
Typ publikacji:
Journal Article
MeSH Terms:
RNA Interference*
Cytokinesis/*physiology
DNA Helicases/*physiology
DNA Repair Enzymes/*physiology
Neuroblastoma/*metabolism
Poly-ADP-Ribose Binding Proteins/*physiology
Apoptosis ; Caspase 3/metabolism ; Caspase 9/metabolism ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cell Survival ; Centrosome ; DNA Helicases/genetics ; DNA Helicases/metabolism ; DNA Repair ; DNA Repair Enzymes/genetics ; Humans ; Poly-ADP-Ribose Binding Proteins/genetics ; Spindle Apparatus
Czasopismo naukowe
Tytuł:
DNA Helicase-Polymerase Coupling in Bacteriophage DNA Replication.
Autorzy:
Lo CY; Department of BioSciences, Rice University, Houston, TX 77005, USA.
Gao Y; Department of BioSciences, Rice University, Houston, TX 77005, USA.
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Źródło:
Viruses [Viruses] 2021 Aug 31; Vol. 13 (9). Date of Electronic Publication: 2021 Aug 31.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
DNA Helicases/*metabolism
DNA Replication/*physiology
DNA-Directed DNA Polymerase/*metabolism
Bacteriophage T4/genetics ; Bacteriophage T7/genetics ; DNA Helicases/chemistry ; DNA Helicases/genetics ; DNA, Viral/chemistry ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; DNA-Directed DNA Polymerase/chemistry ; DNA-Directed DNA Polymerase/genetics ; Kinetics ; Models, Molecular ; Viral Proteins/chemistry ; Viral Proteins/genetics ; Viral Proteins/metabolism ; Virus Replication/physiology
Czasopismo naukowe
Tytuł:
Perspectives and Issues in the Assessment of SMARCA4 Deficiency in the Management of Lung Cancer Patients.
Autorzy:
Armon S; Laboratory of Clinical and Experimental Pathology, Hospital-Integrated Biobank (BB-0033-00025), Nice Hospital University, FHU OncoAge, Université Côte d' Azur, 06000 Nice, France.; Histopathology Unit, Department of Pathology, Hospital Kuala Lumpur, Jalan Pahang, Kuala Lumpur 50586, Malaysia.
Hofman P; Laboratory of Clinical and Experimental Pathology, Hospital-Integrated Biobank (BB-0033-00025), Nice Hospital University, FHU OncoAge, Université Côte d' Azur, 06000 Nice, France.
Ilié M; Laboratory of Clinical and Experimental Pathology, Hospital-Integrated Biobank (BB-0033-00025), Nice Hospital University, FHU OncoAge, Université Côte d' Azur, 06000 Nice, France.
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Źródło:
Cells [Cells] 2021 Jul 29; Vol. 10 (8). Date of Electronic Publication: 2021 Jul 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Adenocarcinoma of Lung/*metabolism
DNA Helicases/*deficiency
DNA Helicases/*genetics
Nuclear Proteins/*deficiency
Nuclear Proteins/*genetics
Transcription Factors/*deficiency
Transcription Factors/*genetics
Adenocarcinoma of Lung/genetics ; Biomarkers, Tumor ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/metabolism ; DNA Helicases/analysis ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Mutation ; Nuclear Proteins/analysis ; Sequence Analysis, DNA ; Transcription Factors/analysis
Czasopismo naukowe
Tytuł:
Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability.
Autorzy:
Hoffmeister H; Department of Biochemistry, Genetics and Microbiology, Biochemistry III, University of Regensburg, Germany.
Fuchs A; Department of Biochemistry, Genetics and Microbiology, Biochemistry III, University of Regensburg, Germany.
Komives E; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA.
Groebner-Ferreira R; Department of Biochemistry, Genetics and Microbiology, Biochemistry III, University of Regensburg, Germany.
Strobl L; Department of Biochemistry, Genetics and Microbiology, Biochemistry III, University of Regensburg, Germany.
Nazet J; Department of Biochemistry II, University of Regensburg, Germany.
Heizinger L; Department of Biochemistry II, University of Regensburg, Germany.
Merkl R; Department of Biochemistry II, University of Regensburg, Germany.
Dove S; Department of Pharmaceutical and Medical Chemistry II, University of Regensburg, Germany.
Längst G; Department of Biochemistry, Genetics and Microbiology, Biochemistry III, University of Regensburg, Germany.
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Źródło:
The FEBS journal [FEBS J] 2021 Jul; Vol. 288 (13), pp. 4000-4023. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenosine Triphosphatases/*metabolism
Adenosine Triphosphate/*metabolism
Chromosomal Proteins, Non-Histone/*metabolism
DNA Helicases/*metabolism
Mi-2 Nucleosome Remodeling and Deacetylase Complex/*metabolism
Adenosine Diphosphate/metabolism ; Adenosine Triphosphatases/chemistry ; Adenosine Triphosphatases/genetics ; Amino Acid Sequence ; Binding, Competitive ; Chromatin/genetics ; Chromatin/metabolism ; Chromatin Assembly and Disassembly ; Chromosomal Proteins, Non-Histone/chemistry ; Chromosomal Proteins, Non-Histone/genetics ; DNA Helicases/chemistry ; DNA Helicases/genetics ; Humans ; Hydrolysis ; Mi-2 Nucleosome Remodeling and Deacetylase Complex/chemistry ; Mi-2 Nucleosome Remodeling and Deacetylase Complex/genetics ; Mutation ; Nucleosomes/genetics ; Nucleosomes/metabolism ; Protein Binding ; Protein Domains ; Sequence Homology, Amino Acid ; Substrate Specificity
Czasopismo naukowe
Tytuł:
Phylogenetic Diversity of Lhr Proteins and Biochemical Activities of the Thermococcales aLhr2 DNA/RNA Helicase.
Autorzy:
Hajj M; Laboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Paul Sabatier, F-31062 Toulouse, France.; Laboratory of Applied Biotechnology (LBA3B), Azm Center for Research in Biotechnology and Its Application, EDST, Lebanese University, Tripoli 1300, Lebanon.
Langendijk-Genevaux P; Laboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Paul Sabatier, F-31062 Toulouse, France.
Batista M; Laboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Paul Sabatier, F-31062 Toulouse, France.
Quentin Y; Laboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Paul Sabatier, F-31062 Toulouse, France.
Laurent S; Ifremer, Univ Brest, CNRS, UMR 6197 Laboratoire de Microbiologie des Environnements Extrêmes, F-29280 Plouzané, France.
Capeyrou R; Laboratoire de Biologie Moléculaire, Cellulaire et du Développement, UMR5077, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Paul Sabatier, F-31062 Toulouse, France.
Abdel-Razzak Z; Laboratory of Applied Biotechnology (LBA3B), Azm Center for Research in Biotechnology and Its Application, EDST, Lebanese University, Tripoli 1300, Lebanon.
Flament D; Ifremer, Univ Brest, CNRS, UMR 6197 Laboratoire de Microbiologie des Environnements Extrêmes, F-29280 Plouzané, France.
Chamieh H; Laboratory of Applied Biotechnology (LBA3B), Azm Center for Research in Biotechnology and Its Application, EDST, Lebanese University, Tripoli 1300, Lebanon.
Fichant G; Laboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Paul Sabatier, F-31062 Toulouse, France.
Clouet-d'Orval B; Laboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Paul Sabatier, F-31062 Toulouse, France.; Laboratoire de Biologie Moléculaire, Cellulaire et du Développement, UMR5077, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Paul Sabatier, F-31062 Toulouse, France.
Bouvier M; Laboratoire de Microbiologie et Génétique Moléculaires, UMR5100, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Paul Sabatier, F-31062 Toulouse, France.; Laboratoire de Biologie Moléculaire, Cellulaire et du Développement, UMR5077, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Paul Sabatier, F-31062 Toulouse, France.
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Źródło:
Biomolecules [Biomolecules] 2021 Jun 26; Vol. 11 (7). Date of Electronic Publication: 2021 Jun 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Helicases/*genetics
RNA Helicases/*genetics
Thermococcales/*enzymology
Adenosine Triphosphatases/genetics ; Archaeal Proteins/chemistry ; DNA/chemistry ; DNA Helicases/isolation & purification ; DNA Helicases/metabolism ; Phylogeny ; RNA/chemistry ; RNA Helicases/isolation & purification ; RNA Helicases/metabolism ; Sequence Homology, Amino Acid ; Thermococcales/genetics ; Thermococcales/metabolism
Czasopismo naukowe
Tytuł:
Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner.
Autorzy:
Gwon Y; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Maxwell BA; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Kolaitis RM; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Zhang P; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Kim HJ; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Taylor JP; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, TN, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2021 Jun 25; Vol. 372 (6549), pp. eabf6548. Date of Electronic Publication: 2021 Aug 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Heat-Shock Response*
Blood Proteins/*metabolism
Cytoplasmic Granules/*metabolism
DNA Helicases/*metabolism
Membrane Proteins/*metabolism
Poly-ADP-Ribose Binding Proteins/*metabolism
RNA Helicases/*metabolism
RNA Recognition Motif Proteins/*metabolism
Ubiquitinated Proteins/*metabolism
Valosin Containing Protein/*metabolism
Autophagy ; Cell Line, Tumor ; DNA Helicases/chemistry ; DNA Helicases/genetics ; Endoplasmic Reticulum/metabolism ; HEK293 Cells ; Humans ; Intracellular Membranes/metabolism ; Mutation ; Poly-ADP-Ribose Binding Proteins/chemistry ; Poly-ADP-Ribose Binding Proteins/genetics ; Polyubiquitin/metabolism ; Protein Domains ; Proteolysis ; RNA Helicases/chemistry ; RNA Helicases/genetics ; RNA Recognition Motif Proteins/chemistry ; RNA Recognition Motif Proteins/genetics ; Ubiquitinated Proteins/chemistry ; Ubiquitination
Czasopismo naukowe

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