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Wyszukujesz frazę ""DNA Repair"" wg kryterium: Temat


Starter badań:

Tytuł:
PRMT5-mediated homologous recombination repair is essential to maintain genomic integrity of neural progenitor cells.
Autorzy:
Wang YJ; Key Laboratory of Molecular Epigenetics, Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China.
Cao JB; Key Laboratory of Molecular Epigenetics, Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China.
Yang J; Key Laboratory of Molecular Epigenetics, Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China.
Liu T; Key Laboratory of Molecular Epigenetics, Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China.
Yu HL; Key Laboratory of Molecular Epigenetics, Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China.
He ZX; Key Laboratory of Molecular Epigenetics, Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China.
Bao SL; State Key Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.
He XX; Key Laboratory of Molecular Epigenetics, Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China. .
Zhu XJ; Key Laboratory of Molecular Epigenetics, Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China. .
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Źródło:
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Mar 08; Vol. 81 (1), pp. 123. Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:
Journal Article
MeSH Terms:
Neural Stem Cells*/metabolism
Recombinational DNA Repair*
Animals ; Mice ; Arginine/metabolism ; DNA Repair ; Genomic Instability ; Genomics ; Histones/genetics ; Histones/metabolism ; Protein-Arginine N-Methyltransferases/genetics ; Protein-Arginine N-Methyltransferases/metabolism
Czasopismo naukowe
Tytuł:
Quantitative, titratable and high-throughput reporter assays to measure DNA double strand break repair activity in cells.
Autorzy:
Rajendra E; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Grande D; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Mason B; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Di Marcantonio D; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Armstrong L; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Hewitt G; The Francis Crick Institute, London NW1 1AT, UK.
Elinati E; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Galbiati A; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Boulton SJ; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.; The Francis Crick Institute, London NW1 1AT, UK.
Heald RA; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Smith GCM; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Robinson HMR; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Feb 28; Vol. 52 (4), pp. 1736-1752.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Repair*/genetics
High-Throughput Screening Assays*
DNA/metabolism ; DNA Breaks, Double-Stranded ; DNA End-Joining Repair ; Homologous Recombination ; Recombinational DNA Repair ; Humans ; Cell Line
Czasopismo naukowe
Tytuł:
Exploring DNA repair deficient CHO cell response to low dose rate radiation.
Autorzy:
Buglewicz DJ; Department of Environmental & Radiological Health Sciences, Colorado State University, USA; Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Duluth, MN, USA.
Haskins JS; Department of Environmental & Radiological Health Sciences, Colorado State University, USA.
Haskins AH; Department of Environmental & Radiological Health Sciences, Colorado State University, USA.
Su C; Department of Environmental & Radiological Health Sciences, Colorado State University, USA.
Gius JP; Department of Environmental & Radiological Health Sciences, Colorado State University, USA.
Kato TA; Department of Environmental & Radiological Health Sciences, Colorado State University, USA. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Feb 26; Vol. 698, pp. 149539. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Repair*/genetics
DNA End-Joining Repair*/genetics
Cricetinae ; Animals ; CHO Cells ; Cricetulus ; Recombinational DNA Repair ; DNA
Czasopismo naukowe
Tytuł:
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.
Autorzy:
Wang Y; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.
Gao B; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.; Department of Molecular Biology and Microbiology, Duke University School of Medicine, 213 Research Drive, Durham, NC, 27710, USA.
Zhang L; Emory University School of Medicine, Atlanta, GA, 30322, USA.
Wang X; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.
Zhu X; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.
Yang H; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.
Zhang F; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.; Department of Molecular Biology and Microbiology, Duke University School of Medicine, 213 Research Drive, Durham, NC, 27710, USA.
Zhu X; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.
Zhou B; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.
Yao S; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.
Nagayama A; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.; Ludwig Center at Harvard, Boston, MA, 02215, USA.
Lee S; UPMC Hillman Cancer Center, University of Pittsburgh, 5117 Centre Ave, Pittsburgh, PA, 15232, USA.; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, 15232, USA.; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, 15232, USA.
Ouyang J; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.
Koh SB; School of Cellular & Molecular Medicine, University of Bristol; University Walk, Bristol, BS8 1TD, UK.
Eisenhauer EL; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, 55 Fruit St, Massachusetts General Hospital, Boston, MA, 02114, USA.; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, 02115, USA.
Zarrella D; Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, 55 Fruit St, Massachusetts General Hospital, Boston, MA, 02114, USA.
Lu K; David H. Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Rueda BR; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, 55 Fruit St, Massachusetts General Hospital, Boston, MA, 02114, USA.; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, 02115, USA.; Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, 55 Fruit St, Massachusetts General Hospital, Boston, MA, 02114, USA.
Zou L; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA, 02114, USA.; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, 213 Research Drive, Durham, NC, 27710, USA.
Su XA; David H. Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Yeku O; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.; Division of Hematology-Oncology, Massachusetts General Hospital, 55 Fruit St, Boston, MA, 02114, USA.; Department of Medicine, Massachusetts General Hospital, 55 Fruit St, Boston, MA, 02114, USA.
Ellisen LW; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA.; Ludwig Center at Harvard, Boston, MA, 02215, USA.
Wang XS; UPMC Hillman Cancer Center, University of Pittsburgh, 5117 Centre Ave, Pittsburgh, PA, 15232, USA.; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, 15232, USA.; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, 15232, USA.
Lan L; Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, MA, 02129, USA. .; Department of Molecular Biology and Microbiology, Duke University School of Medicine, 213 Research Drive, Durham, NC, 27710, USA. .
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Źródło:
Nature communications [Nat Commun] 2024 Feb 21; Vol. 15 (1), pp. 1568. Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
R-Loop Structures*
DNA Repair*
DNA Breaks, Double-Stranded ; Homologous Recombination ; BRCA1 Protein/genetics ; BRCA1 Protein/metabolism ; DNA ; Rad51 Recombinase/genetics ; Rad51 Recombinase/metabolism ; Recombinational DNA Repair
Czasopismo naukowe
Tytuł:
MutSβ protects common fragile sites by facilitating homology-directed repair at DNA double-strand breaks with secondary structures.
Autorzy:
Li Y; Beijing Key Laboratory of DNA Damage Response and College of Life Sciences, Capital Normal University, Beijing 100048, China.; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Zhang Y; Beijing Key Laboratory of DNA Damage Response and College of Life Sciences, Capital Normal University, Beijing 100048, China.
Shah SB; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Chang CY; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Wang H; Beijing Key Laboratory of DNA Damage Response and College of Life Sciences, Capital Normal University, Beijing 100048, China.
Wu X; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Feb 09; Vol. 52 (3), pp. 1120-1135.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Breaks, Double-Stranded*
DNA Repair*/genetics
DNA Replication/genetics ; Recombinational DNA Repair ; DNA/genetics ; DNA/metabolism ; Proteins/genetics
Czasopismo naukowe
Tytuł:
AND Logic Gate-Regulated DNAzyme Nanoflower for Monitoring the Activity of Multiple DNA Repair Enzymes.
Autorzy:
Zeng WJ; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
Li XR; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
Liu W; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
Yuan R; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
Liang WB; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
Zhuo Y; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
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Źródło:
Analytical chemistry [Anal Chem] 2024 Feb 06; Vol. 96 (5), pp. 2117-2123. Date of Electronic Publication: 2024 Jan 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Repair*
DNA, Catalytic*
DNA Damage ; DNA Repair Enzymes/genetics ; DNA-(Apurinic or Apyrimidinic Site) Lyase/metabolism ; DNA/chemistry
Czasopismo naukowe
Tytuł:
Metabolic regulation of homologous recombination repair by MRE11 lactylation.
Autorzy:
Chen Y; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China.
Wu J; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China.
Zhai L; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing, China.
Zhang T; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Yin H; Department of Thoracic Surgery, The First Affiliated Hospital of Shaoyang University, Shaoyang 422001, China.
Gao H; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.
Zhao F; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Wang Z; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China.
Yang X; Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Jin M; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China.
Huang B; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China.
Ding X; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China.
Li R; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China.
Yang J; Department of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
He Y; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China.
Wang Q; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China.
Wang W; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Kloeber JA; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA; Mayo Clinic Medical Scientist Training Program, Mayo Clinic Alix School of Medicine and Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Li Y; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Hao B; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing, China.
Zhang Y; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Wang J; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Tan M; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing, China.
Li K; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Wang P; Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Shanghai 200072, China.
Lou Z; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Yuan J; State Key Laboratory of Cardiology and Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China. Electronic address: .
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Źródło:
Cell [Cell] 2024 Jan 18; Vol. 187 (2), pp. 294-311.e21. Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA-Binding Proteins*/metabolism
MRE11 Homologue Protein*/metabolism
Recombinational DNA Repair*
Humans ; DNA ; DNA Breaks, Double-Stranded ; DNA Repair ; Epigenesis, Genetic ; Homologous Recombination ; Lactic Acid/metabolism
Czasopismo naukowe
Tytuł:
Characterization of the RAD52 Gene in the Budding Yeast Naumovozyma castellii .
Autorzy:
Itriago H; Department of Biology, Genetics Group, Lund University, Sölvegatan 35, SE-223 62 Lund, Sweden.
Marufee Islam Z; Department of Biology, Genetics Group, Lund University, Sölvegatan 35, SE-223 62 Lund, Sweden.
Cohn M; Department of Biology, Genetics Group, Lund University, Sölvegatan 35, SE-223 62 Lund, Sweden.
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Źródło:
Genes [Genes (Basel)] 2023 Oct 05; Vol. 14 (10). Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Rad52 DNA Repair and Recombination Protein*/genetics
Rad52 DNA Repair and Recombination Protein*/metabolism
DNA Repair/genetics ; DNA-Binding Proteins/genetics ; Genome, Fungal
SCR Organism:
Naumovozyma castellii
Czasopismo naukowe
Tytuł:
Fibrillarin promotes homologous recombination repair by facilitating the recruitment of recombinase RAD51 to DNA damage sites.
Autorzy:
Mu Y; National-Local Joint Engineering Research Center of Biodiagnosis & Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China.; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
Han J; Zhejiang Provincial Key Lab of Geriatrics and Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310030, China.
Wu M; Trauma Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Li Z; National-Local Joint Engineering Research Center of Biodiagnosis & Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China.
DU K; National-Local Joint Engineering Research Center of Biodiagnosis & Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China.
Wei Y; National-Local Joint Engineering Research Center of Biodiagnosis & Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China.
Wu M; The Affiliated Hospital of Stomatology, School of Stomatology, Zhejiang University School of Medicine, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Hangzhou 310006, China. , .
Huang J; Zhejiang Provincial Key Lab of Geriatrics and Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310030, China. .; Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China. .; Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China. .
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Transliterated Title:
纤维蛋白通过促进重组酶RAD51在DNA损伤位点的招募参与同源重组修复.
Źródło:
Journal of Zhejiang University. Science. B [J Zhejiang Univ Sci B] 2023 Dec 15; Vol. 24 (12), pp. 1165-1173.
Typ publikacji:
Journal Article
MeSH Terms:
Recombinational DNA Repair*
DNA-Binding Proteins*/metabolism
DNA Repair ; DNA Damage ; DNA
Czasopismo naukowe
Tytuł:
A Novel Interaction Between RAD23A/B and Y-family DNA Polymerases.
Autorzy:
Ashton NW; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892-3371, USA. Electronic address: nicholas_.
Jaiswal N; Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT 06032, USA. Electronic address: .
Moreno NC; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892-3371, USA. Electronic address: .
Semenova IV; Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT 06032, USA. Electronic address: .
D'Orlando DA; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892-3371, USA. Electronic address: .
Latancia MT; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892-3371, USA. Electronic address: .
McIntyre J; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892-3371, USA. Electronic address: .
Woodgate R; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892-3371, USA. Electronic address: .
Bezsonova I; Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT 06032, USA. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2023 Dec 15; Vol. 435 (24), pp. 168353. Date of Electronic Publication: 2023 Nov 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural
MeSH Terms:
DNA-Directed DNA Polymerase*/metabolism
DNA-Binding Proteins*/chemistry
DNA Repair Enzymes*/chemistry
DNA Damage ; DNA Polymerase iota/chemistry ; DNA Repair ; DNA Replication ; Ubiquitins/chemistry
Czasopismo naukowe
Tytuł:
STAG2 Regulates Homologous Recombination Repair and Sensitivity to ATM Inhibition.
Autorzy:
Zhou J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Guangxi International Travel Healthcare Centre (Port Clinic of Nanning Customs District), Nanning, Guangxi, 530021, China.
Nie RC; Department of Gastric Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
He ZP; Department of Pathology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Cai XX; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Chen JW; Department of Pathology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Lin WP; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Yin YX; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Xiang ZC; Department of Pathology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Zhu TC; Department of Pathology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Xie JJ; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Zhang YC; Department of Pathology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Wang X; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Lin P; Department of Thoracic Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Xie D; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Pathology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
D'Andrea AD; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
Cai MY; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Pathology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
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Źródło:
Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2023 Dec; Vol. 10 (36), pp. e2302494. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Recombinational DNA Repair*/genetics
Neoplasms*/drug therapy
Humans ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use ; DNA Repair/genetics ; Cohesins ; Ataxia Telangiectasia Mutated Proteins/genetics ; Ataxia Telangiectasia Mutated Proteins/metabolism
Czasopismo naukowe
Tytuł:
Multi-step processing of replication stress-derived nascent strand DNA gaps by MRE11 and EXO1 nucleases.
Autorzy:
Hale A; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Dhoonmoon A; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Straka J; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Nicolae CM; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA. .
Moldovan GL; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA. .
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Źródło:
Nature communications [Nat Commun] 2023 Oct 07; Vol. 14 (1), pp. 6265. Date of Electronic Publication: 2023 Oct 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
DNA Repair*
Exodeoxyribonucleases*/metabolism
Humans ; Endonucleases/genetics ; Endonucleases/metabolism ; DNA/genetics ; Genomic Instability ; DNA Replication ; DNA, Single-Stranded/genetics ; DNA Repair Enzymes/metabolism
Czasopismo naukowe
Tytuł:
Requirement of WDR70 for POLE3-mediated DNA double-strand breaks repair.
Autorzy:
Mao X; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.
Wu J; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.
Zhang Q; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.
Zhang S; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.
Chen X; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.
Liu X; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.
Wei M; Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Wan X; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.
Qiu L; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.
Zeng M; Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education), West China Second University hospital, Sichuan University, Chengdu 610041, China.
Lei X; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.
Liu C; Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education), West China Second University hospital, Sichuan University, Chengdu 610041, China.
Han J; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.
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Źródło:
Science advances [Sci Adv] 2023 Sep 08; Vol. 9 (36), pp. eadh2358. Date of Electronic Publication: 2023 Sep 08.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Breaks, Double-Stranded*
DNA Repair*
Mutation ; Protein Processing, Post-Translational ; Recombinational DNA Repair
Czasopismo naukowe
Tytuł:
Protein Phosphatase 4 Is Required for Centrobin Function in DNA Damage Repair.
Autorzy:
Réthi-Nagy Z; MTA SZBK Lendület Laboratory of Cell Cycle Regulation, Institute of Biochemistry, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary.; Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
Ábrahám E; MTA SZBK Lendület Laboratory of Cell Cycle Regulation, Institute of Biochemistry, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary.; National Laboratory for Biotechnology, Institute of Genetics, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary.
Sinka R; Department of Genetics, University of Szeged, H-6726 Szeged, Hungary.
Juhász S; Institute of Biochemistry, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary.
Lipinszki Z; MTA SZBK Lendület Laboratory of Cell Cycle Regulation, Institute of Biochemistry, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary.; National Laboratory for Biotechnology, Institute of Genetics, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary.
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Źródło:
Cells [Cells] 2023 Sep 06; Vol. 12 (18). Date of Electronic Publication: 2023 Sep 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Repair*
Phosphoprotein Phosphatases*/genetics
Humans ; Recombinational DNA Repair ; DNA Damage
Czasopismo naukowe
Tytuł:
RBM14 promotes DNA end resection during homologous recombination repair.
Autorzy:
Li Z; College of Life Sciences, Capital Normal University, Beijing 100048, China.; Guangdong Key Laboratory for Genome Stability & Disease Prevention and Carson International Cancer Center, Marshall Laboratory of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China.
Liao Y; Guangdong Key Laboratory for Genome Stability & Disease Prevention and Carson International Cancer Center, Marshall Laboratory of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China.
Tang C; State Key Laboratory of Agro-biotechnology and MOA Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100091, China.; Shenzhen University General Hospital-Dehua Hospital Joint Research Center on Precision Medicine (sgh-dhhCPM), Dehua Hospital, Dehua 362500, China.
Xu L; College of Life Sciences, Capital Normal University, Beijing 100048, China.
Peng B; Guangdong Key Laboratory for Genome Stability & Disease Prevention and Carson International Cancer Center, Marshall Laboratory of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China.
Xu X; Guangdong Key Laboratory for Genome Stability & Disease Prevention and Carson International Cancer Center, Marshall Laboratory of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China.
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Źródło:
Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2023 Aug 10; Vol. 55 (12), pp. 1864-1873.
Typ publikacji:
Journal Article
MeSH Terms:
Recombinational DNA Repair*
DNA Breaks, Double-Stranded*
DNA Repair ; Homologous Recombination ; Replication Protein A/genetics ; DNA/genetics ; DNA End-Joining Repair
Czasopismo naukowe
Tytuł:
SETD2 variation correlates with tumor mutational burden and MSI along with improved response to immunotherapy.
Autorzy:
Zheng X; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Lin J; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Xiong J; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Guan Y; Geneplus-Beijing Institute, Beijing, China.
Lan B; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Li Y; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Gao X; Geneplus-Beijing Institute, Beijing, China.
Fei Z; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Chen L; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Chen L; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Chen L; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Chen G; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Department of Pathology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Guo Z; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Yi X; Geneplus-Beijing Institute, Beijing, China.
Cao W; Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ai X; Department of Shanghai Lung Cancer Center, Shanghai Jiao Tong University Affiliated Chest Hospital, Shanghai, China.
Zhou C; First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Li X; Department of Oncology, Affiliated Quanzhou First Hospital of Fujian Medical University, Quanzhou, Fujian Province, China.
Zhao J; Department of Thoracic Oncology, Peking University Cancer Hospital & Institute, Beijing, China.
Yan X; Department of Internal Medicine, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Henan Province, Zhengzhou, China.
Yu Q; Department of Oncology, The Cancer Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi Zhuang Autonomous Region, China.
Si L; Department of Renal Cancer and Melanoma, Peking University Cancer Hospital and Institute, Beijing, China.
Chen Y; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China. .; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China. .
Chen C; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China. .; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Jul 21; Vol. 23 (1), pp. 686. Date of Electronic Publication: 2023 Jul 21.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Repair*/genetics
Microsatellite Instability*
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/mortality
Humans ; Asian People ; Cohort Studies ; DNA Mismatch Repair/genetics ; Genomic Instability ; Immunotherapy ; Mutation ; Recombinational DNA Repair/genetics
Czasopismo naukowe
Tytuł:
MND1 enables homologous recombination in somatic cells primarily outside the context of replication.
Autorzy:
Koob L; Division of Cell Biology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Friskes A; Division of Cell Biology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
van Bergen L; Division of Cell Biology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Feringa FM; Division of Cell Biology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
van den Broek B; Bioimaging Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Koeleman ES; Division of Cell Biology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
van Beek E; Division of Cell Biology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Schubert M; Division of Cell Biology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Blomen VA; Division of Biochemistry, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Brummelkamp TR; Division of Biochemistry, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Krenning L; Division of Cell Biology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Medema RH; Division of Cell Biology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
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Źródło:
Molecular oncology [Mol Oncol] 2023 Jul; Vol. 17 (7), pp. 1192-1211. Date of Electronic Publication: 2023 Jun 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Repair*/genetics
Homologous Recombination*/genetics
Humans ; DNA Breaks, Double-Stranded ; Recombinational DNA Repair ; S Phase ; Cell Cycle Proteins/metabolism
Czasopismo naukowe
Tytuł:
Saccharomyces cerevisiae DNA polymerase IV overcomes Rad51 inhibition of DNA polymerase δ in Rad52-mediated direct-repeat recombination.
Autorzy:
Cerqueira PG; Department of Microbiology and Molecular Genetics, University of California, Davis, One Shields Avenue, Davis, CA 95616-8665, USA.
Meyer D; Department of Microbiology and Molecular Genetics, University of California, Davis, One Shields Avenue, Davis, CA 95616-8665, USA.
Zhang L; Department of Microbiology and Molecular Genetics, University of California, Davis, One Shields Avenue, Davis, CA 95616-8665, USA.
Mallory B; Department of Microbiology and Molecular Genetics, University of California, Davis, One Shields Avenue, Davis, CA 95616-8665, USA.
Liu J; Department of Microbiology and Molecular Genetics, University of California, Davis, One Shields Avenue, Davis, CA 95616-8665, USA.
Hua Fu BX; Department of Microbiology and Molecular Genetics, University of California, Davis, One Shields Avenue, Davis, CA 95616-8665, USA.
Zhang X; Department of Microbiology and Molecular Genetics, University of California, Davis, One Shields Avenue, Davis, CA 95616-8665, USA.
Heyer WD; Department of Microbiology and Molecular Genetics, University of California, Davis, One Shields Avenue, Davis, CA 95616-8665, USA.; Department of Molecular and Cellular Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616-8665, USA.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2023 Jun 23; Vol. 51 (11), pp. 5547-5564.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Polymerase beta*/genetics
Rad51 Recombinase*/genetics
Rad51 Recombinase*/metabolism
Rad52 DNA Repair and Recombination Protein*/genetics
Rad52 DNA Repair and Recombination Protein*/metabolism
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Humans ; DNA/metabolism ; DNA Polymerase III/genetics ; DNA Polymerase III/metabolism ; DNA Repair ; Recombinational DNA Repair
Czasopismo naukowe
Tytuł:
Functional analysis of a conserved site mutation in the DNA end processing enzyme PNKP leading to ataxia with oculomotor apraxia type 4 in humans.
Autorzy:
Islam A; Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA.
Chakraborty A; Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA.
Gambardella S; IRCCS Neuromed & Department of Biomolecular Sciences, University of Urbino 'Carlo Bo', Urbino, Italy.
Campopiano R; IRCCS Neuromed & Department of Biomolecular Sciences, University of Urbino 'Carlo Bo', Urbino, Italy.
Sarker AH; Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Boldogh I; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Hazra T; Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 May; Vol. 299 (5), pp. 104714. Date of Electronic Publication: 2023 Apr 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Repair Enzymes*/metabolism
Leukocytes, Mononuclear*/metabolism
Phosphotransferases (Alcohol Group Acceptor)*/metabolism
Spinocerebellar Ataxias*/genetics
Humans ; DNA ; DNA Repair ; Mutation
Czasopismo naukowe
Tytuł:
Visualizing the coordination of apurinic/apyrimidinic endonuclease (APE1) and DNA polymerase β during base excision repair.
Autorzy:
Fairlamb MS; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Spies M; Department of Biochemistry and Molecular Biology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Washington MT; Department of Biochemistry and Molecular Biology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Freudenthal BD; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, USA; University of Kansas Cancer Center, Kansas City, Kansas, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 May; Vol. 299 (5), pp. 104636. Date of Electronic Publication: 2023 Mar 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Polymerase beta*/genetics
DNA Polymerase beta*/metabolism
DNA Repair*/physiology
DNA Damage ; DNA Repair Enzymes/genetics ; DNA Repair Enzymes/metabolism ; DNA-(Apurinic or Apyrimidinic Site) Lyase/genetics ; DNA-(Apurinic or Apyrimidinic Site) Lyase/metabolism ; Single Molecule Imaging ; Microscopy, Fluorescence ; Humans
Czasopismo naukowe

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