Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""DNA Repair"" wg kryterium: Temat


Tytuł:
Cellular Responses to Widespread DNA Replication Stress.
Autorzy:
Nickoloff JA; Department of Environmental and Radiological Health Sciences, Colorado State University, Ft. Collins, CO 80523, USA.
Jaiswal AS; Department of Medicine and the Mays Cancer Center, The University of Texas Health Science Center San Antonio, San Antonio, TX 78229, USA.
Sharma N; Department of Environmental and Radiological Health Sciences, Colorado State University, Ft. Collins, CO 80523, USA.
Williamson EA; Department of Medicine and the Mays Cancer Center, The University of Texas Health Science Center San Antonio, San Antonio, TX 78229, USA.
Tran MT; Department of Medicine and the Mays Cancer Center, The University of Texas Health Science Center San Antonio, San Antonio, TX 78229, USA.
Arris D; Department of Medicine and the Mays Cancer Center, The University of Texas Health Science Center San Antonio, San Antonio, TX 78229, USA.
Yang M; Department of Medicine and the Mays Cancer Center, The University of Texas Health Science Center San Antonio, San Antonio, TX 78229, USA.
Hromas R; Department of Medicine and the Mays Cancer Center, The University of Texas Health Science Center San Antonio, San Antonio, TX 78229, USA.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 29; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
DNA Replication*
DNA Repair*
Humans ; DNA Damage ; Endonucleases/metabolism ; Genomic Instability ; DNA ; Nucleotides
Czasopismo naukowe
Tytuł:
REV7 Monomer Is Unable to Participate in Double Strand Break Repair and Translesion Synthesis but Suppresses Mitotic Errors.
Autorzy:
Vassel FM; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Laverty DJ; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA 02115, USA.
Bian K; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Piett CG; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA 02115, USA.
Hemann MT; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Walker GC; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Nagel ZD; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA 02115, USA.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 31; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Repair*
DNA Replication*
Animals ; Mice ; Anaphase-Promoting Complex-Cyclosome/metabolism ; Mad2 Proteins/genetics ; Mad2 Proteins/metabolism ; Mitosis/genetics
Czasopismo naukowe
Tytuł:
CSB Regulates Pathway Choice in Response to DNA Replication Stress Induced by Camptothecin.
Autorzy:
Batenburg NL; Department of Biology, McMaster University, Hamilton, ON L8S 4K1, Canada.
Walker JR; Department of Biology, McMaster University, Hamilton, ON L8S 4K1, Canada.
Zhu XD; Department of Biology, McMaster University, Hamilton, ON L8S 4K1, Canada.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 04; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Replication*
DNA Repair*
DNA End-Joining Repair ; Camptothecin/pharmacology
Czasopismo naukowe
Tytuł:
The Adaptive Mechanisms and Checkpoint Responses to a Stressed DNA Replication Fork.
Autorzy:
Saldanha J; The Graduate Program in Genetics, Stony Brook University, Stony Brook, NY 11794, USA.; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY 11794, USA.
Rageul J; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY 11794, USA.
Patel JA; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY 11794, USA.
Kim H; The Graduate Program in Genetics, Stony Brook University, Stony Brook, NY 11794, USA.; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY 11794, USA.; Stony Brook Cancer Center, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 22; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
DNA Replication*
DNA Repair*
Ataxia Telangiectasia Mutated Proteins/genetics ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Cell Cycle ; DNA ; DNA Damage ; Checkpoint Kinase 1/metabolism
Czasopismo naukowe
Tytuł:
Targeting Replication Stress Response Pathways to Enhance Genotoxic Chemo- and Radiotherapy.
Autorzy:
Nickoloff JA; Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jul 25; Vol. 27 (15). Date of Electronic Publication: 2022 Jul 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
DNA Repair*
DNA Replication*
Cell Cycle Proteins/metabolism ; DNA Damage ; Endodeoxyribonucleases/metabolism ; Homologous Recombination ; Humans
Czasopismo naukowe
Tytuł:
The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication.
Autorzy:
Davarinejad H; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
Huang YC; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.
Mermaz B; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.
LeBlanc C; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.
Poulet A; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.
Thomson G; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.
Joly V; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.
Muñoz M; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.; Epigenetics Programme, Babraham Institute, Cambridge CB22 3AT, UK.
Arvanitis-Vigneault A; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
Valsakumar D; BEaTS Research Laboratory, Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario K1Y 4W7, Canada.; Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
Villarino G; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.
Ross A; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.; Epigenetics Programme, Babraham Institute, Cambridge CB22 3AT, UK.
Rotstein BH; Epigenetics Programme, Babraham Institute, Cambridge CB22 3AT, UK.; University of Ottawa Heart Institute, Ottawa, Ontario K1Y 4W7, Canada.
Alarcon EI; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.; Epigenetics Programme, Babraham Institute, Cambridge CB22 3AT, UK.
Brunzelle JS; Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Voigt P; BEaTS Research Laboratory, Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario K1Y 4W7, Canada.; Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
Dong J; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.; Institute of Crop Science, Zhejiang University, Hangzhou 310058, China.
Couture JF; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
Jacob Y; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2022 Mar 18; Vol. 375 (6586), pp. 1281-1286. Date of Electronic Publication: 2022 Mar 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Repair*
DNA Replication*
Arabidopsis/*genetics
Arabidopsis Proteins/*metabolism
DNA, Plant/*metabolism
Histones/*metabolism
Arabidopsis/metabolism ; Arabidopsis Proteins/chemistry ; Arabidopsis Proteins/genetics ; DNA Breaks, Double-Stranded ; DNA-Directed DNA Polymerase/genetics ; DNA-Directed DNA Polymerase/metabolism ; Genome, Plant ; Genomic Instability ; Histones/chemistry ; Lysine/metabolism ; Methylation ; Methyltransferases/genetics ; Mutation ; Protein Interaction Domains and Motifs ; DNA Polymerase theta
Czasopismo naukowe
Tytuł:
Limiting DNA polymerase delta alters replication dynamics and leads to a dependence on checkpoint activation and recombination-mediated DNA repair.
Autorzy:
Koussa NC; Department of Biology, New York University, New York City, New York, United State of America.
Smith DJ; Department of Biology, New York University, New York City, New York, United State of America.
Pokaż więcej
Źródło:
PLoS genetics [PLoS Genet] 2021 Jan 25; Vol. 17 (1), pp. e1009322. Date of Electronic Publication: 2021 Jan 25 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
DNA Polymerase III/*genetics
DNA Replication/*genetics
Proliferating Cell Nuclear Antigen/*genetics
Recombinational DNA Repair/*genetics
DNA Damage/genetics ; DNA Repair/genetics ; Genes, cdc/genetics ; Humans ; Replication Origin/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł:
Safeguarding DNA Replication: A Golden Touch of MiDAS and Other Mechanisms.
Autorzy:
Al Ahmad Nachar B; CNRS UMR9019, Gustave Roussy Cancer Campus, Université Paris-Saclay, Equipe Labellisée Ligue Nationale Contre le Cancer, 94801 Villejuif, France.
Rosselli F; CNRS UMR9019, Gustave Roussy Cancer Campus, Université Paris-Saclay, Equipe Labellisée Ligue Nationale Contre le Cancer, 94801 Villejuif, France.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 26; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
DNA Replication*
DNA Repair ; Mitosis/genetics ; S Phase
Czasopismo naukowe
Tytuł:
R-Loops and Its Chro-Mates: The Strange Case of Dr. Jekyll and Mr. Hyde.
Autorzy:
Uruci S; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.
Lo CSY; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.
Wheeler D; Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Taneja N; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 17; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Chromatin Assembly and Disassembly*
DNA Damage*
DNA Repair*
DNA Replication*
Genomic Instability*
R-Loop Structures*
Humans
Czasopismo naukowe
Tytuł:
Creation and resolution of non-B-DNA structural impediments during replication.
Autorzy:
Mellor C; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK.
Perez C; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK.
Sale JE; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK.
Pokaż więcej
Źródło:
Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2022 Aug; Vol. 57 (4), pp. 412-442. Date of Electronic Publication: 2022 Sep 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Helicases*/genetics
DNA Replication*
DNA/genetics ; DNA Repair ; Humans ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł:
Structural and Molecular Kinetic Features of Activities of DNA Polymerases.
Autorzy:
Kuznetsova AA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Fedorova OS; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Kuznetsov NA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 07; Vol. 23 (12). Date of Electronic Publication: 2022 Jun 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
DNA Replication*
DNA-Directed DNA Polymerase*/metabolism
DNA/chemistry ; DNA Repair ; Humans ; Kinetics ; Phylogeny
Czasopismo naukowe
Tytuł:
Kinetics of DNA Repair in Vicia faba Meristem Regeneration Following Replication Stress.
Autorzy:
Rybaczek D; Department of Cytophysiology, Institute of Experimental Biology, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Musiałek MW; Department of Cytophysiology, Institute of Experimental Biology, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Vrána J; Centre of Plant Structural and Functional Genomics, Institute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Haná for Biotechnological and Agricultural Research, Šlechtitelů 31, CZ-77900 Olomouc, Czech Republic.
Petrovská B; Centre of Plant Structural and Functional Genomics, Institute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Haná for Biotechnological and Agricultural Research, Šlechtitelů 31, CZ-77900 Olomouc, Czech Republic.
Pikus EG; Department of Cytophysiology, Institute of Experimental Biology, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.; Department of Biodiversity Studies and Bioeducation, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 1/3, 90-237 Lodz, Poland.
Doležel J; Centre of Plant Structural and Functional Genomics, Institute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Haná for Biotechnological and Agricultural Research, Šlechtitelů 31, CZ-77900 Olomouc, Czech Republic.
Pokaż więcej
Źródło:
Cells [Cells] 2021 Jan 07; Vol. 10 (1). Date of Electronic Publication: 2021 Jan 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Repair*
DNA Replication*
Stress, Physiological*
Meristem/*physiology
Regeneration/*physiology
Vicia faba/*physiology
Chromosomes, Plant/genetics ; DNA Damage ; Fluorescence ; Heterochromatin/metabolism ; Kinetics
Czasopismo naukowe
Tytuł:
Are the processes of DNA replication and DNA repair reading a common structural chromatin unit?
Autorzy:
Mamberti S; Cell Biology and Epigenetics, Department of Biology, Technische Universität Darmstadt, Darmstadt, Germany.
Cardoso MC; Cell Biology and Epigenetics, Department of Biology, Technische Universität Darmstadt, Darmstadt, Germany.
Pokaż więcej
Źródło:
Nucleus (Austin, Tex.) [Nucleus] 2020 Dec; Vol. 11 (1), pp. 66-82.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
DNA Repair*
DNA Replication*
Chromatin/*chemistry
Chromatin/*genetics
DNA/*chemistry
DNA/*genetics
Animals ; Chromatin/metabolism ; DNA/metabolism ; Humans ; Molecular Conformation
Czasopismo naukowe
Tytuł:
Characterisation of the spectrum and genetic dependence of collateral mutations induced by translesion DNA synthesis.
Autorzy:
Póti Á; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
Szikriszt B; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
Gervai JZ; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
Chen D; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
Szüts D; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
Pokaż więcej
Źródło:
PLoS genetics [PLoS Genet] 2022 Feb 07; Vol. 18 (2), pp. e1010051. Date of Electronic Publication: 2022 Feb 07 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Replication*/genetics
DNA-Directed DNA Polymerase*/genetics
DNA-Directed DNA Polymerase*/metabolism
DNA/genetics ; DNA Damage/genetics ; DNA Repair/genetics ; Mutation ; Proliferating Cell Nuclear Antigen/genetics
Czasopismo naukowe
Tytuł:
Dynamic elements of replication protein A at the crossroads of DNA replication, recombination, and repair.
Autorzy:
Caldwell CC; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Spies M; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Pokaż więcej
Źródło:
Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2020 Oct; Vol. 55 (5), pp. 482-507. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms:
DNA Repair*
DNA Replication*
Recombination, Genetic*
Eukaryota/*metabolism
Replication Protein A/*metabolism
Animals ; DNA, Single-Stranded/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Eukaryota/genetics ; Humans ; Protein Conformation ; Replication Protein A/genetics
Czasopismo naukowe
Tytuł:
Berberine inhibits non-small cell lung cancer cell growth through repressing DNA repair and replication rather than through apoptosis.
Autorzy:
Ni L; Department of Basic Medicine, Jiangnan University, Wuxi, China.
Li Z; Department of Basic Medicine, Jiangnan University, Wuxi, China.
Ren H; The Institute of Science, Technology and Humanities, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Kong L; Department of Rehabilitation Acupuncture Medicine, Bozhou People's Hospital, Bozhou, China.
Chen X; Department of Basic Medicine, Jiangnan University, Wuxi, China.
Xiong M; Department of Basic Medicine, Jiangnan University, Wuxi, China.
Zhang X; Department of Respiratory Medicine, Affiliated Hospital of Jiangnan University, Wuxi, China.
Ning B; Department of Cardiology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Li J; Department of Emergency, Wuxi No 2 People's Hospital, Wuxi, China.
Pokaż więcej
Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2022 Jan; Vol. 49 (1), pp. 134-144. Date of Electronic Publication: 2021 Oct 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Apoptosis/*drug effects
Berberine/*therapeutic use
Carcinoma, Non-Small-Cell Lung/*drug therapy
DNA Repair/*drug effects
DNA Replication/*drug effects
Lung Neoplasms/*drug therapy
Animals ; Antineoplastic Agents/pharmacology ; Berberine/pharmacology ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Mice ; Neoplasm Transplantation ; Oligonucleotide Array Sequence Analysis
Czasopismo naukowe
Tytuł:
Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer.
Autorzy:
Keijzers G; Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. .
Bakula D; Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. .
Petr MA; Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. .; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA. .
Madsen NGK; Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. .
Teklu A; Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. .
Mkrtchyan G; Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. .
Osborne B; Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. .
Scheibye-Knudsen M; Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. .
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2018 Dec 25; Vol. 20 (1). Date of Electronic Publication: 2018 Dec 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
DNA Replication*
DNA Repair Enzymes/*metabolism
Exodeoxyribonucleases/*metabolism
Apoptosis ; Cell Cycle Checkpoints ; DNA Breaks, Double-Stranded ; DNA Repair ; Homologous Recombination ; Humans ; Neoplasms/metabolism ; Neoplasms/pathology
Czasopismo naukowe
Tytuł:
Using a Human Papillomavirus Model to Study DNA Replication and Repair of Wild Type and Damaged DNA Templates in Mammalian Cells.
Autorzy:
Das D; Department of Oral and Craniofacial Molecular Biology, VCU Philips Institute for Oral Health Research, Virginia Commonwealth University School of Dentistry, Richmond, VA 23298, USA.
Bristol ML; Department of Oral and Craniofacial Molecular Biology, VCU Philips Institute for Oral Health Research, Virginia Commonwealth University School of Dentistry, Richmond, VA 23298, USA.
Pichierri P; Department of Environment and Health, Istituto Superiore di Sanita', 00161 Rome, Italy.
Morgan IM; Department of Oral and Craniofacial Molecular Biology, VCU Philips Institute for Oral Health Research, Virginia Commonwealth University School of Dentistry, Richmond, VA 23298, USA.; VCU Massey Cancer Center, Richmond, VA 23298, USA.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 13; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
DNA Repair*
DNA Replication*
Alphapapillomavirus/*genetics
Alphapapillomavirus/metabolism ; Animals ; DNA Damage ; Genetic Engineering/methods ; Humans
Czasopismo naukowe
Tytuł:
Chromatin Trapping of Factors Involved in DNA Replication and Repair Underlies Heat-Induced Radio- and Chemosensitization.
Autorzy:
Luzhin AV; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia.
Avanesyan B; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.
Velichko AK; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia.; Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Shender VO; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.
Ovsyannikova N; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Arapidi GP; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.; Moscow Institute of Physics and Technology (State University), 141701 Moscow, Russia.
Shnaider PV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.
Petrova NV; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.
Kireev II; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, 117997 Moscow, Russia.
Razin SV; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.; Department of Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Kantidze OL; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.
Pokaż więcej
Źródło:
Cells [Cells] 2020 Jun 08; Vol. 9 (6). Date of Electronic Publication: 2020 Jun 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Repair*/radiation effects
DNA Replication*/radiation effects
Hot Temperature*
Chromatin/*metabolism
DNA/metabolism ; DNA Damage ; HEK293 Cells ; HeLa Cells ; Humans ; Nuclear Proteins/metabolism ; Poly Adenosine Diphosphate Ribose/metabolism ; Poly(ADP-ribose) Polymerases/metabolism
Czasopismo naukowe
Tytuł:
Medium levels of transcription and replication related chromosomal instability are associated with poor clinical outcome.
Autorzy:
Benhaddou A; OncoSarc, INSERM U1037, Cancer Research Center in Toulouse (CRCT), 31000, Toulouse, France.
Gaston L; Department of Medical Genetics, CHU de Bordeaux, 33000, Bordeaux, France.
Pérot G; OncoSarc, INSERM U1037, Cancer Research Center in Toulouse (CRCT), 31000, Toulouse, France.; Centre Hospitalier Universitaire (CHU) de Toulouse, IUCT-Oncopole, 31000, Toulouse, France.
Desplat N; INSERM UMR1218, ACTION, Institut Bergonié, 33000, Bordeaux, France.
Leroy L; OncoSarc, INSERM U1037, Cancer Research Center in Toulouse (CRCT), 31000, Toulouse, France.; Department of Pathology, Institut Claudius Régaud, IUCT-Oncopole, 31000, Toulouse, France.
Le Guellec S; OncoSarc, INSERM U1037, Cancer Research Center in Toulouse (CRCT), 31000, Toulouse, France.; Department of Pathology, Institut Claudius Régaud, IUCT-Oncopole, 31000, Toulouse, France.
Ben Haddou M; Mentis Consulting, 1000, Brussels, Belgique.
Rochaix P; OncoSarc, INSERM U1037, Cancer Research Center in Toulouse (CRCT), 31000, Toulouse, France.; Department of Pathology, Institut Claudius Régaud, IUCT-Oncopole, 31000, Toulouse, France.
Valentin T; OncoSarc, INSERM U1037, Cancer Research Center in Toulouse (CRCT), 31000, Toulouse, France.; Department of Oncology, Institut Claudius Régaud, IUCT-Oncopole, 31000, Toulouse, France.
Ferron G; OncoSarc, INSERM U1037, Cancer Research Center in Toulouse (CRCT), 31000, Toulouse, France.; Department of Surgical Oncology, Institut Claudius Régaud, IUCT-Oncopole, 31000, Toulouse, France.
Chevreau C; Department of Oncology, Institut Claudius Régaud, IUCT-Oncopole, 31000, Toulouse, France.
Bui B; Department of Oncology, Institut Bergonié, 33000, Bordeaux, France.
Stoeckle E; Department of Surgery, Institut Bergonié, 33000, Bordeaux, France.
Le Cesne A; Department of Oncology, Institut Gustave Roussy, 94800, Villejuif, France.
Piperno-Neumann S; Department of Medical Oncology, Institut Curie, 75005, Paris, France.
Collin F; Department of Pathology, Centre Georges-François Leclerc, 21000, Dijon, France.
Firmin N; Department of Oncology, Institut Régional du Cancer de Montpellier, 34000, Montpellier, France.
De Pinieux G; Department of Pathology, Hôpital Universitaire Trousseau, 37170, Tours, France.
Coindre JM; Department of Pathology, Institut Bergonié, 33000, Bordeaux, France.
Blay JY; Department of Medical Oncology, Centre Léon Bérard, 69000, Lyon, France.; Centre Léon Bérard, Université Claude Bernard Lyon 1, INSERM U1052, CNRS 5286, 69000, Lyon, France.
Chibon F; OncoSarc, INSERM U1037, Cancer Research Center in Toulouse (CRCT), 31000, Toulouse, France. .; Department of Pathology, Institut Claudius Régaud, IUCT-Oncopole, 31000, Toulouse, France. .; Cancer Research Center in Toulouse (CRCT), 2 Avenue Hubert Curien, 31037, Toulouse, France. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Dec 06; Vol. 11 (1), pp. 23429. Date of Electronic Publication: 2021 Dec 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chromosomal Instability*
DNA Replication*
Chromosomes/*ultrastructure
Algorithms ; Antineoplastic Agents/administration & dosage ; DNA/analysis ; DNA Damage ; DNA Mutational Analysis ; DNA Repair ; Enhancer Elements, Genetic ; Gene Regulatory Networks ; Genome, Human ; Humans ; Kaplan-Meier Estimate ; Neoplasm Metastasis ; Neoplasms/genetics ; Promoter Regions, Genetic ; Risk ; Sarcoma/pathology ; Sequence Analysis, DNA ; Transcription, Genetic ; Treatment Outcome
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies