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Tytuł :
Colon fibroblasts from Pirc rats (F344/NTac-Apc ) exhibit a proliferative and inflammatory phenotype that could support early stages of colon carcinogenesis.
Autorzy :
Tortora K; NEUROFARBA Department, Pharmacology and Toxicology Section, University of Florence, Florence, Italy.
Margheri F; Department of Experimental and Clinical Biomedical Sciences Mario Serio, University of Florence, Florence, Italy.
Luceri C; NEUROFARBA Department, Pharmacology and Toxicology Section, University of Florence, Florence, Italy.
Mocali A; Department of Experimental and Clinical Biomedical Sciences Mario Serio, University of Florence, Florence, Italy.
Ristori S; NEUROFARBA Department, Pharmacology and Toxicology Section, University of Florence, Florence, Italy.
Magnelli L; Department of Experimental and Clinical Biomedical Sciences Mario Serio, University of Florence, Florence, Italy.
Caderni G; NEUROFARBA Department, Pharmacology and Toxicology Section, University of Florence, Florence, Italy.
Giovannelli L; NEUROFARBA Department, Pharmacology and Toxicology Section, University of Florence, Florence, Italy.
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Źródło :
International journal of cancer [Int J Cancer] 2022 Jan 15; Vol. 150 (2), pp. 362-373. Date of Electronic Publication: 2021 Sep 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
DNA Damage*
Genes, APC*
Colon/*pathology
Colonic Neoplasms/*pathology
Fibroblasts/*pathology
Inflammation/*pathology
Animals ; Apoptosis ; Colon/metabolism ; Colonic Neoplasms/etiology ; Colonic Neoplasms/metabolism ; Fibroblasts/metabolism ; Inflammation/etiology ; Inflammation/metabolism ; Mutation ; Phenotype ; Rats ; Rats, Inbred F344
Czasopismo naukowe
Tytuł :
How can environmental conditions influence dicofol genotoxicity on the edible Asiatic clam, Meretrix meretrix?
Autorzy :
Ivorra L; Institute of Science and Environment, ISE-University of Saint Joseph, Macao.
Cruzeiro C; Helmholtz Zentrum München, German Research Centre for Environmental Health, GmbH, Research Unit Comparative Microbiome Analysis, Ingolstaedter Landstrasse 1, 85764, Neuherberg, Germany; Department of Life Sciences, CFE-Centre for Functional Ecology, University of Coimbra, Coimbra, Portugal.
Ramos A; Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto (U.Porto), Porto, Portugal; CIIMAR-Interdisciplinary Centre for Marine and Environmental Research, University of Porto, Matosinhos, Portugal.
Tagulao K; Institute of Science and Environment, ISE-University of Saint Joseph, Macao.
Cardoso PG; CIIMAR-Interdisciplinary Centre for Marine and Environmental Research, University of Porto, Matosinhos, Portugal. Electronic address: .
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Źródło :
Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2022 Jan 15; Vol. 293, pp. 118467. Date of Electronic Publication: 2021 Nov 05.
Typ publikacji :
Journal Article
MeSH Terms :
Bivalvia*/drug effects
Bivalvia*/genetics
DNA Damage*
Dicofol*/toxicity
Animals ; Comet Assay ; Hydrogen Peroxide/toxicity
Czasopismo naukowe
Tytuł :
Blue light induces DNA damage in normal human skin keratinocytes.
Autorzy :
Chamayou-Robert C; Coty Lancaster R&D Technology & Innovation Laboratories, Monaco, Monaco.
DiGiorgio C; Laboratoire de Mutagénèse Environnementale, Aix-Marseille Université, CNRS, IRD, Avignon Université, IMBE UMR 7263, Marseille, France.
Brack O; K.S.I.C., Statistique Industrielle -Khi² - Consulting, 347 rue des sources, Monaco, Monaco.
Doucet O; Coty Lancaster R&D Technology & Innovation Laboratories, Monaco, Monaco.
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Źródło :
Photodermatology, photoimmunology & photomedicine [Photodermatol Photoimmunol Photomed] 2022 Jan; Vol. 38 (1), pp. 69-75. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Damage*
Pyrimidine Dimers*
DNA Repair ; Humans ; Keratinocytes ; Light ; Ultraviolet Rays/adverse effects
Czasopismo naukowe
Tytuł :
DNA damage response proteins synergistically affect the cancer prognosis and resistance.
Autorzy :
Sharma M; Functional Genomics and Complex System Lab, Department of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176 061, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Anand P; Pharmacology and Toxicology Lab, Dietetics & Nutrition Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176 061, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Padwad YS; Pharmacology and Toxicology Lab, Dietetics & Nutrition Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176 061, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address: .
Dogra V; Plant Molecular Biology and Stress Signalling Lab, Department of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176 061, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address: .
Acharya V; Functional Genomics and Complex System Lab, Department of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176 061, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2022 Jan; Vol. 178, pp. 174-188. Date of Electronic Publication: 2021 Nov 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage*
Neoplasms*/drug therapy
Neoplasms*/genetics
Cell Cycle Checkpoints ; DNA Repair ; Humans ; Hydrogen Peroxide ; Network Pharmacology
Czasopismo naukowe
Tytuł :
Epithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal Carcinogenesis.
Autorzy :
Welz L; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Internal Medicine I, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Kakavand N; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Hang X; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Laue G; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Ito G; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Silva MG; Center for Translational Cancer Research (TranslaTUM), Technische Universität München, Munich, Germany.
Plattner C; Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria.
Mishra N; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Tengen F; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany.
Ogris C; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany.
Jesinghaus M; Institute of Pathology, University Hospital Marburg, Marburg, Germany.
Wottawa F; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Arnold P; Institute of Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany.
Kaikkonen L; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts.
Stengel S; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Tran F; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Internal Medicine I, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Das S; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts.
Kaser A; Division of Gastroenterology and Hepatology, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Trajanoski Z; Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria.
Blumberg R; Gastroenterology Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Roecken C; Department of Pathology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Saur D; Center for Translational Cancer Research (TranslaTUM), Technische Universität München, Munich, Germany.
Tschurtschenthaler M; Center for Translational Cancer Research (TranslaTUM), Technische Universität München, Munich, Germany.
Schreiber S; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Internal Medicine I, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Rosenstiel P; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. Electronic address: .
Aden K; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Internal Medicine I, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. Electronic address: .
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Źródło :
Gastroenterology [Gastroenterology] 2022 Jan; Vol. 162 (1), pp. 223-237.e11. Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Damage*
Adenocarcinoma/*metabolism
Adenoma/*metabolism
Cell Transformation, Neoplastic/*metabolism
Epithelial Cells/*metabolism
Intestinal Mucosa/*metabolism
Intestinal Neoplasms/*metabolism
X-Box Binding Protein 1/*metabolism
Adaptor Proteins, Signal Transducing/metabolism ; Adenocarcinoma/drug therapy ; Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Adenoma/drug therapy ; Adenoma/genetics ; Adenoma/pathology ; Animals ; Cell Cycle Proteins/metabolism ; Cell Transformation, Neoplastic/drug effects ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/pathology ; Databases, Genetic ; Endoplasmic Reticulum Stress ; Epithelial Cells/drug effects ; Epithelial Cells/pathology ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Humans ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/pathology ; Intestinal Neoplasms/drug therapy ; Intestinal Neoplasms/genetics ; Intestinal Neoplasms/pathology ; MTOR Inhibitors/pharmacology ; Mice, Knockout ; Signal Transduction ; Sirolimus/pharmacology ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; X-Box Binding Protein 1/genetics
Czasopismo naukowe
Tytuł :
GSTpi reduces DNA damage and cell death by regulating the ubiquitination and nuclear translocation of NBS1.
Autorzy :
Zhou J; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, No.1 Wenyuan Road, Nanjing, 210046, People's Republic of China.
Gu L; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, No.1 Wenyuan Road, Nanjing, 210046, People's Republic of China.
Shi Y; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, No.1 Wenyuan Road, Nanjing, 210046, People's Republic of China.
Huang T; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, No.1 Wenyuan Road, Nanjing, 210046, People's Republic of China.
Fan X; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, No.1 Wenyuan Road, Nanjing, 210046, People's Republic of China.
Bi X; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, No.1 Wenyuan Road, Nanjing, 210046, People's Republic of China.
Lu S; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, No.1 Wenyuan Road, Nanjing, 210046, People's Republic of China.
Liang J; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, No.1 Wenyuan Road, Nanjing, 210046, People's Republic of China.
Luo L; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, People's Republic of China. .
Cao P; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China. .; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China. .
Yin Z; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, No.1 Wenyuan Road, Nanjing, 210046, People's Republic of China. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Dec 22; Vol. 79 (1), pp. 54. Date of Electronic Publication: 2021 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Damage*
Cell Cycle Proteins/*metabolism
Glutathione S-Transferase pi/*physiology
Nijmegen Breakage Syndrome/*metabolism
Nuclear Proteins/*metabolism
HEK293 Cells ; Humans ; MCF-7 Cells ; Phosphorylation ; Ubiquitination
Czasopismo naukowe
Tytuł :
Mechanisms and Regulation of Cellular Senescence.
Autorzy :
Roger L; Structure and Instability of Genomes Laboratory, Muséum National d'Histoire Naturelle (MNHN), CNRS-UMR 7196/INSERM U1154, 43 Rue Cuvier, 75005 Paris, France.
Tomas F; Centre de Recherche en Biologie cellulaire de Montpellier (CRBM), Université de Montpellier, CNRS UMR 5237, 1919 Route de Mende, 34293 Montpellier, France.
Gire V; Centre de Recherche en Biologie cellulaire de Montpellier (CRBM), Université de Montpellier, CNRS UMR 5237, 1919 Route de Mende, 34293 Montpellier, France.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 06; Vol. 22 (23). Date of Electronic Publication: 2021 Dec 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Aging*
Cellular Senescence*
DNA Damage*
Senescence-Associated Secretory Phenotype*
Inflammation/*pathology
Animals ; Humans ; Inflammation/etiology ; Signal Transduction
Czasopismo naukowe
Tytuł :
The base excision repair process: comparison between higher and lower eukaryotes.
Autorzy :
Hindi NN; Division of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Education City, Doha, Qatar.
Elsakrmy N; Division of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Education City, Doha, Qatar.
Ramotar D; Division of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Education City, Doha, Qatar. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Dec; Vol. 78 (24), pp. 7943-7965. Date of Electronic Publication: 2021 Nov 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Damage*
DNA Repair*
DNA-Binding Proteins/*metabolism
Drosophila melanogaster/*genetics
Saccharomyces cerevisiae/*genetics
Animals ; DNA-Binding Proteins/genetics ; Drosophila melanogaster/metabolism ; Humans ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł :
Regulation of the Cell-Intrinsic DNA Damage Response by the Innate Immune Machinery.
Autorzy :
Hayman TJ; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Glazer PM; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 25; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Damage*
DNA Repair*
Immunity, Innate*
Membrane Proteins/*metabolism
Nucleotidyltransferases/*metabolism
Humans ; Membrane Proteins/genetics ; Nucleotidyltransferases/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
The Influence of 5',8-Cyclo-2'-deoxypurines on the Mitochondrial Repair of Clustered DNA Damage in Xrs5 Cells: The Preliminary Study.
Autorzy :
Boguszewska K; DNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Poland.
Kaźmierczak-Barańska J; DNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Poland.
Karwowski BT; DNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Poland.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Nov 22; Vol. 26 (22). Date of Electronic Publication: 2021 Nov 22.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Damage*
DNA Repair*
Oligonucleotides*/chemistry
Oligonucleotides*/pharmacology
Purine Nucleosides*/chemistry
Purine Nucleosides*/pharmacology
DNA, Mitochondrial/*metabolism
Animals ; CHO Cells ; Cricetulus
Czasopismo naukowe
Tytuł :
Effects of 5',8'-Cyclo-2'-Deoxypurines on the Base Excision Repair of Clustered DNA Lesions in Nuclear Extracts of the XPC Cell Line.
Autorzy :
Kaźmierczak-Barańska J; DNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, 90-151 Lodz, Poland.
Boguszewska K; DNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, 90-151 Lodz, Poland.
Szewczuk M; DNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, 90-151 Lodz, Poland.
Karwowski BT; DNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, 90-151 Lodz, Poland.
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Źródło :
Cells [Cells] 2021 Nov 20; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage*
DNA Repair*/drug effects
Cell Nucleus/*pathology
Purines/*pharmacology
Xeroderma Pigmentosum/*pathology
Cell Line ; Cell Nucleus/drug effects ; Humans ; Substrate Specificity/drug effects
Czasopismo naukowe
Tytuł :
SARS-CoV-2 triggers DNA damage response in Vero E6 cells.
Autorzy :
Victor J; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA.
Deutsch J; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA.
Whitaker A; Division of Immunobiology, Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA.
Lamkin EN; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA.
March A; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA.
Zhou P; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA.
Botten JW; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA; Division of Immunobiology, Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA.
Chatterjee N; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA; Division of Immunobiology, Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA; University of Vermont Cancer Center, University of Vermont, Burlington, VT, 05405, USA. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Nov 19; Vol. 579, pp. 141-145. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage*
COVID-19/*genetics
Host-Pathogen Interactions/*genetics
SARS-CoV-2/*pathogenicity
Animals ; Ataxia Telangiectasia Mutated Proteins/genetics ; Checkpoint Kinase 1/metabolism ; Chlorocebus aethiops ; Histones/genetics ; Phosphorylation ; Telomere ; Vero Cells
Czasopismo naukowe
Tytuł :
Effect of Cold Atmospheric Plasma on Epigenetic Changes, DNA Damage, and Possibilities for Its Use in Synergistic Cancer Therapy.
Autorzy :
Braný D; Biomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Dvorská D; Biomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Strnádel J; Biomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Matáková T; Department of Medical Biochemistry, Jessenius Faculty of Medicine in Martin, Comenius University, Bratislava, 036 01 Martin, Slovakia.
Halašová E; Biomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Škovierová H; Biomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 12; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Damage*
Antineoplastic Agents/*therapeutic use
Epigenesis, Genetic/*drug effects
Neoplasms/*drug therapy
Plasma Gases/*therapeutic use
Animals ; Apoptosis/drug effects ; Apoptosis/genetics ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Drug Synergism ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Neoplasms/genetics ; Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Alterations in blood parameters, DNA damage, oxidative stress and antioxidant enzymes and immune-related genes expression in Nile tilapia (Oreochromis niloticus) exposed to glyphosate-based herbicide.
Autorzy :
Acar Ü; Çanakkale Onsekiz Mart University, Bayramiç Vocational School, Department of Forestry, Çanakkale, Turkey. Electronic address: .
İnanan BE; Aksaray University, Faculty of Veterinary Medicine, Department of Fisheries and Diseases, Aksaray, Turkey. Electronic address: .
Navruz FZ; Bartın University, Faculty of Science, Department of Molecular Biology and Genetics, Turkey.
Yılmaz S; Çanakkale Onsekiz Mart University, Marine Science and Technlogy Faculty, Department of Aquaculture, Çanakkale, Turkey. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP [Comp Biochem Physiol C Toxicol Pharmacol] 2021 Nov; Vol. 249, pp. 109147. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Cichlids*/blood
Cichlids*/metabolism
DNA Damage*
Fish Proteins/*immunology
Glycine/*analogs & derivatives
Oxidative Stress/*drug effects
Animals ; Antioxidants/metabolism ; Enzymes/metabolism ; Fish Proteins/genetics ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/immunology ; Glycine/toxicity ; Herbicides/toxicity ; Lethal Dose 50 ; Lipid Peroxidation/drug effects ; Liver/drug effects ; Liver/physiology ; Oxidative Stress/physiology ; Toxicity Tests, Acute ; Water Pollutants, Chemical/toxicity
Czasopismo naukowe
Tytuł :
Persistent DNA damage alters the neuronal transcriptome suggesting cell cycle dysregulation and altered mitochondrial function.
Autorzy :
Vazquez-Villasenor I; Sheffield Institute for Translational Neuroscience, The University of Sheffield, Sheffield, UK.
Garwood CJ; Sheffield Institute for Translational Neuroscience, The University of Sheffield, Sheffield, UK.
Simpson JE; Sheffield Institute for Translational Neuroscience, The University of Sheffield, Sheffield, UK.
Heath PR; Sheffield Institute for Translational Neuroscience, The University of Sheffield, Sheffield, UK.
Mortiboys H; Sheffield Institute for Translational Neuroscience, The University of Sheffield, Sheffield, UK.
Wharton SB; Sheffield Institute for Translational Neuroscience, The University of Sheffield, Sheffield, UK.
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Źródło :
The European journal of neuroscience [Eur J Neurosci] 2021 Nov; Vol. 54 (9), pp. 6987-7005. Date of Electronic Publication: 2021 Oct 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage*
Transcriptome*
Cell Cycle ; Mitochondria/metabolism ; Neurons/metabolism ; Oxidative Stress
Czasopismo naukowe
Tytuł :
DNA Damage and Expression Profile of Genes Associated with Nephrotoxicity Induced by Butralin and Ameliorating Effect of Arabic Gum in Female Rats.
Autorzy :
Refaie AA; Environmental Toxicology Research Unit (ETRU), Pesticide Chemistry Department, National Research Centre (NRC), 33 El Bohouth Street, P.O. 12622, Dokki, Giza, Egypt.
Shalby AB; Department of Hormones, National Research Centre (NRC), 33 El Bohouth Street, P.O. 12622, Dokki, Giza, Egypt. .
Kassem SM; Department of Cell Biology, National Research Centre, 33-Bohouth St., P.O. 12622, Dokki, Giza, Egypt.
Khalil WKB; Department of Cell Biology, National Research Centre, 33-Bohouth St., P.O. 12622, Dokki, Giza, Egypt.
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Źródło :
Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2021 Nov; Vol. 193 (11), pp. 3454-3468. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Damage*
Kidney Diseases*/chemically induced
Kidney Diseases*/drug therapy
Kidney Diseases*/metabolism
Transcriptome*
Aniline Compounds/*toxicity
Gum Arabic/*pharmacology
Kidney/*metabolism
Animals ; Female ; Gene Expression Regulation/drug effects ; Rats
Czasopismo naukowe
Tytuł :
Avermectin induces toxic effects in insect nontarget cells involves DNA damage and its associated programmed cell death.
Autorzy :
Li M; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Zhang P; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Xu W; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Yuan J; CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China.
Li Q; CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China.
Tao L; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Li Z; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Zhang Y; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP [Comp Biochem Physiol C Toxicol Pharmacol] 2021 Nov; Vol. 249, pp. 109130. Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Damage*
Apoptosis/*drug effects
Insect Proteins/*metabolism
Ivermectin/*analogs & derivatives
Spodoptera/*drug effects
Animals ; Autophagy/drug effects ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Ivermectin/toxicity ; Reactive Oxygen Species/metabolism ; Spodoptera/cytology ; Spodoptera/metabolism
Czasopismo naukowe
Tytuł :
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication.
Autorzy :
Arena A; Department of Experimental Medicine, 'Sapienza' University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.
Gilardini Montani MS; Department of Experimental Medicine, 'Sapienza' University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.
Romeo MA; Department of Experimental Medicine, 'Sapienza' University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.
Benedetti R; Department of Experimental Medicine, 'Sapienza' University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.
Gaeta A; Department of Molecular Medicine, 'Sapienza' University of Rome, Rome, Italy.
Cirone M; Department of Experimental Medicine, 'Sapienza' University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2022 Jan; Vol. 1869 (1), pp. 119168. Date of Electronic Publication: 2021 Oct 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
DNA Damage*
Virus Replication*
Lymphoma, Primary Effusion/*metabolism
Proto-Oncogene Proteins c-myc/*metabolism
Tumor Suppressor Protein p53/*metabolism
Cell Line ; Cells, Cultured ; Checkpoint Kinase 1/antagonists & inhibitors ; Checkpoint Kinase 1/metabolism ; Herpesvirus 8, Human/physiology ; Humans ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism ; Lymphoma, Primary Effusion/genetics ; Lymphoma, Primary Effusion/virology ; Phthalazines/pharmacology ; Piperidines/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors/toxicity ; Protein Kinase Inhibitors/toxicity ; Staurosporine/analogs & derivatives ; Staurosporine/pharmacology
Czasopismo naukowe
Tytuł :
Genotoxic and cytotoxic evaluation of venlafaxine in an acute and a subchronic assay in mouse.
Autorzy :
Madrigal-Bujaidar E; Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Zacatenco, Ciudad de México, México.
Gómez-González P; Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Zacatenco, Ciudad de México, México.
Camacho-Cantera S; Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Zacatenco, Ciudad de México, México.
Morales-González JA; Instituto Politécnico Nacional, Escuela Superior de Medicina, Laboratorio de Medicina de la Conservación, Casco de Santo Tomás, Ciudad de México, México.
Madrigal-Santillán E; Instituto Politécnico Nacional, Escuela Superior de Medicina, Laboratorio de Medicina de la Conservación, Casco de Santo Tomás, Ciudad de México, México.
Álvarez-González I; Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Zacatenco, Ciudad de México, México.
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Źródło :
Brazilian journal of biology = Revista brasleira de biologia [Braz J Biol] 2021 Dec 20; Vol. 84, pp. e251289. Date of Electronic Publication: 2021 Dec 20 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*
DNA Damage*
Animals ; Dose-Response Relationship, Drug ; Erythrocytes ; Mice ; Micronucleus Tests ; Venlafaxine Hydrochloride/toxicity
Czasopismo naukowe
Tytuł :
Exposure to nivalenol declines mouse oocyte quality via inducing oxidative stress-related apoptosis and DNA damage†.
Autorzy :
Wang Y; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Xing CH; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Zhang HL; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Pan ZN; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Sun SC; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
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Źródło :
Biology of reproduction [Biol Reprod] 2021 Dec 20; Vol. 105 (6), pp. 1474-1483.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
DNA Damage*
Oxidative Stress*
Melatonin/*pharmacology
Mycotoxins/*toxicity
Oocytes/*drug effects
Protective Agents/*pharmacology
Trichothecenes/*toxicity
Animals ; Mice ; Oocytes/physiology
Czasopismo naukowe

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