Temat: "DNA damage" - OpacWWW

Стрибайте на позицію: 1.

Tytuł:: FLASH Radiotherapy: Expectations, Challenges, and Current Knowledge.
Autorzy:: Borghini A; CNR Institute of Clinical Physiology, 56124 Pisa, Italy.
Labate L; Intense Laser Irradiation Laboratory (ILIL), CNR Istituto Nazionale di Ottica, 56124 Pisa, Italy.
Piccinini S; Intense Laser Irradiation Laboratory (ILIL), CNR Istituto Nazionale di Ottica, 56124 Pisa, Italy.
Panaino CMV; Intense Laser Irradiation Laboratory (ILIL), CNR Istituto Nazionale di Ottica, 56124 Pisa, Italy.
Andreassi MG; CNR Institute of Clinical Physiology, 56124 Pisa, Italy.
Gizzi LA; Intense Laser Irradiation Laboratory (ILIL), CNR Istituto Nazionale di Ottica, 56124 Pisa, Italy.; Показати більше
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 22; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Motivation*
DNA Damage*
Humans ; Head ; Plasma ; Radiobiology

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Стрибайте на позицію: 2.

Tytuł:: DNA Double Strand Break and Response Fluorescent Assays: Choices and Interpretation.
Autorzy:: Atkinson J; Future Industries Institute, University of South Australia, Mawson Lakes, SA 5095, Australia.
Bezak E; UniSA Allied Health and Human Performance, University of South Australia, Adelaide, SA 5095, Australia.; Department of Physics, University of Adelaide, North Terrace, Adelaide, SA 5005, Australia.
Le H; UniSA Allied Health and Human Performance, University of South Australia, Adelaide, SA 5095, Australia.; Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
Kempson I; Future Industries Institute, University of South Australia, Mawson Lakes, SA 5095, Australia.; Показати більше
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:: Journal Article; Review
MeSH Terms:: DNA Breaks, Double-Stranded*
DNA Damage*
DNA/metabolism ; DNA Repair ; DNA End-Joining Repair

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Стрибайте на позицію: 3.

Tytuł:: New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways.
Autorzy:: Waters KL; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.
Spratt DE; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.; Показати більше
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 30; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:: Journal Article; Review
MeSH Terms:: DNA Repair*
DNA Damage*
Humans ; DNA End-Joining Repair ; Genomic Instability ; DNA

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Стрибайте на позицію: 4.

Tytuł:: Key Proteins of Replication Stress Response and Cell Cycle Control as Cancer Therapy Targets.
Autorzy:: Khamidullina AI; Laboratory of Molecular Oncobiology, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.
Abramenko YE; Laboratory of Molecular Oncobiology, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.
Bruter AV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.
Tatarskiy VV; Laboratory of Molecular Oncobiology, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.; Показати більше
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 19; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:: Journal Article; Review
MeSH Terms:: DNA Damage*
Neoplasms*/drug therapy
Neoplasms*/genetics
Ataxia Telangiectasia Mutated Proteins/metabolism ; Checkpoint Kinase 1/genetics ; Checkpoint Kinase 1/metabolism ; Cell Cycle Checkpoints ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; DNA Replication

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Стрибайте на позицію: 5.

Tytuł:: SMC5/6 Promotes Replication Fork Stability via Negative Regulation of the COP9 Signalosome.
Autorzy:: Xu MJ; Department of Biochemistry and Molecular Biology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Jordan PW; Department of Biochemistry and Molecular Biology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.; Department of Biochemistry and Molecular Biology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.; Показати більше
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 12; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:: Journal Article
MeSH Terms:: Cell Nucleus*
Cullin Proteins*
DNA Damage Tolerance*
Animals ; Mice ; Cell Cycle Proteins/genetics ; Cell Proliferation ; COP9 Signalosome Complex/genetics ; Indoleacetic Acids

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Стрибайте на позицію: 6.

Tytuł:: Impact of diffused versus vasculature targeted DNA damage on the heart of mice depleted of telomeric factor Ft1.
Autorzy:: La Torre M; Department Biology and Biotechnologies 'Charles Darwin', Sapienza University, Rome, Italy.
Centofante E; Department Biology and Biotechnologies 'Charles Darwin', Sapienza University, Rome, Italy.
Nicoletti C; DAHFMO-Unit of Histology and Medical Embryology, Sapienza University, Rome, Italy.; Istituto Pasteur Fondazione Cenci Bolognetti, Rome, Italy.
Burla R; Department Biology and Biotechnologies 'Charles Darwin', Sapienza University, Rome, Italy.; CNR Institute of Molecular Biology and Pathology, Rome, Italy.
Giampietro A; Department Biology and Biotechnologies 'Charles Darwin', Sapienza University, Rome, Italy.
Cannistrà F; Department Biology and Biotechnologies 'Charles Darwin', Sapienza University, Rome, Italy.
Schirone L; IRCCS Neuromed, Pozzilli IS, Italy.
Valenti V; Department of Cardiology, Santa Maria Goretti Hospital, Latina, Italy.
Sciarretta S; IRCCS Neuromed, Pozzilli IS, Italy.; Department Medical and Surgical Sciences and Biotechnologies, Sapienza University, Rome, Italy.
Musarò A; DAHFMO-Unit of Histology and Medical Embryology, Sapienza University, Rome, Italy.; Istituto Pasteur Fondazione Cenci Bolognetti, Rome, Italy.
Saggio I; Department Biology and Biotechnologies 'Charles Darwin', Sapienza University, Rome, Italy.; Istituto Pasteur Fondazione Cenci Bolognetti, Rome, Italy.; CNR Institute of Molecular Biology and Pathology, Rome, Italy.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.; NISB Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore.; Показати більше
Źródło:: Aging cell [Aging Cell] 2023 Dec; Vol. 22 (12), pp. e14022. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Damage*/genetics
Telomere*/genetics
Telomere*/metabolism
Animals ; Humans ; Mice ; Adaptor Proteins, Signal Transducing/genetics ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Heart Ventricles/metabolism ; Myocytes, Cardiac/metabolism

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Стрибайте на позицію: 7.

Tytuł:: Molecular cloning, subcellular localization, and rapid recruitment to DNA damage sites of chicken Ku70.
Autorzy:: Koike M; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan. .; Life Science Course, Graduate School of Science and Engineering, Saitama University, 255 Shimo-Okubo, Sakura-ku, Saitama, Saitama, 338-8570, Japan. .
Yamashita H; Department of Food and Life Sciences, School of Agriculture, Tokai University, 9-1-1 Toroku, Higashi-ku, Kumamoto, 862-8652, Japan.
Yutoku Y; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.
Koike A; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.; Показати більше
Źródło:: Scientific reports [Sci Rep] 2024 Jan 12; Vol. 14 (1), pp. 1188. Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:: Journal Article
MeSH Terms:: Antigens, Nuclear*/metabolism
Chickens*/genetics
Chickens*/metabolism
DNA Damage*/genetics
Ku Autoantigen*/genetics
Ku Autoantigen*/metabolism
Animals ; Amino Acids/genetics ; Cloning, Molecular ; DNA Repair ; DNA, Complementary ; DNA-Binding Proteins/metabolism ; Mammals/metabolism

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Стрибайте на позицію: 8.

Tytuł:: Filming DNA repair at the atomic level.
Autorzy:: Vos MH; Laboratoire d'Optique et Biosciences, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, École Polytechnique, Institut Polytechnique de Paris, 91120 Palaiseau, France.; Показати більше
Źródło:: Science (New York, N.Y.) [Science] 2023 Dec; Vol. 382 (6674), pp. 996-997. Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Repair*
Deoxyribodipyrimidine Photo-Lyase*/chemistry
Pyrimidine Dimers*/chemistry
DNA Damage*
Catalysis ; DNA/chemistry ; DNA/radiation effects ; Ultraviolet Rays

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Стрибайте на позицію: 9.

Tytuł:: Evaluation of haematological, genotoxic, cytotoxic and ATR-FTIR alterations in blood cells of fish Channa punctatus after acute exposure of aniline.
Autorzy:: Sharma G; Cytogenetics Lab, Department of Zoology, Guru Nanak Dev University, Amritsar, 143005, India.
Chadha P; Cytogenetics Lab, Department of Zoology, Guru Nanak Dev University, Amritsar, 143005, India. .; Показати більше
Źródło:: Scientific reports [Sci Rep] 2023 Nov 25; Vol. 13 (1), pp. 20757. Date of Electronic Publication: 2023 Nov 25.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Damage*
Water Pollutants, Chemical*/toxicity
Animals ; Spectroscopy, Fourier Transform Infrared ; Comet Assay ; Fishes/genetics ; Blood Cells ; Aniline Compounds/toxicity

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Стрибайте на позицію: 10.

Tytuł:: p53 and p21 dynamics encode single-cell DNA damage levels, fine-tuning proliferation and shaping population heterogeneity.
Autorzy:: Gutu N; Charité Universitätsmedizin, Charité Comprehensive Cancer Center, Berlin, Germany.; Humboldt-Universität zu Berlin, Berlin, Germany.
Binish N; Charité Universitätsmedizin, Charité Comprehensive Cancer Center, Berlin, Germany.; Hertie Institute for Clinical Brain Research, Center for Neurology, University Medical Center Tübingen, Tübingen, Germany.
Keilholz U; Charité Universitätsmedizin, Charité Comprehensive Cancer Center, Berlin, Germany.; German Cancer Consortium, Deutschen Konsortiums für Translationale Krebsforschung (DKTK), Berlin, Germany.
Herzel H; Charité Universitätsmedizin, Charité Comprehensive Cancer Center, Berlin, Germany.; Humboldt-Universität zu Berlin, Berlin, Germany.; Institute for Theoretical Biology, Berlin, Germany.
Granada AE; Charité Universitätsmedizin, Charité Comprehensive Cancer Center, Berlin, Germany. .; German Cancer Consortium, Deutschen Konsortiums für Translationale Krebsforschung (DKTK), Berlin, Germany. .; Показати більше
Źródło:: Communications biology [Commun Biol] 2023 Nov 24; Vol. 6 (1), pp. 1196. Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
DNA Damage*
Humans ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Signal Transduction ; Cell Proliferation

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Стрибайте на позицію: 11.

Tytuł:: X-ray and DNA Damage: Limitations of the Dose as a Parameter for In Vitro Studies.
Autorzy:: Udroiu I; Department of Sciences, Università Roma Tre, Viale G. Marconi 446, 00146 Rome, Italy.
Sgura A; Department of Sciences, Università Roma Tre, Viale G. Marconi 446, 00146 Rome, Italy.; Показати більше
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 23; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 23.
Typ publikacji:: Journal Article
MeSH Terms:: Photons*
DNA Damage*
X-Rays ; Radiography ; Cell Survival/radiation effects ; Dose-Response Relationship, Radiation

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Стрибайте на позицію: 12.

Tytuł:: Sensing chemical-induced genotoxicity and oxidative stress via yeast-based reporter assays using NanoLuc luciferase.
Autorzy:: Shichinohe M; Molecular Genetics Laboratory, Toyohashi, Japan.
Ohkawa S; Molecular Genetics Laboratory, Toyohashi, Japan.
Hirose Y; Department of Applied Chemistry and Life Science, Laboratory of Genomics and Photobiology, Toyohashi University of Technology, Toyohashi, Aichi, Japan.
Eki T; Molecular Genetics Laboratory, Toyohashi, Japan.; Показати більше
Źródło:: PloS one [PLoS One] 2023 Nov 22; Vol. 18 (11), pp. e0294571. Date of Electronic Publication: 2023 Nov 22 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
DNA Damage*
Humans ; Genes, Reporter ; Luciferases/genetics ; Luciferases/metabolism ; Oxidative Stress/genetics

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Стрибайте на позицію: 13.

Tytuł:: Untousling the Role of Tousled-like Kinase 1 in DNA Damage Repair.
Autorzy:: Ghosh I; Department of Medicine, Department of Biochemistry, Louisiana Health Science Center-Shreveport, Shreveport, LA 71103, USA.
De Benedetti A; Department of Medicine, Department of Biochemistry, Louisiana Health Science Center-Shreveport, Shreveport, LA 71103, USA.; Показати більше
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 29; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 29.
Typ publikacji:: Journal Article; Review
MeSH Terms:: DNA Damage*/genetics
DNA Repair*/genetics
Protein Serine-Threonine Kinases*/metabolism
Cell Survival ; Combined Modality Therapy ; Mutagens

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Стрибайте на позицію: 14.

Tytuł:: Effect of pachymaran on oxidative stress and DNA damage induced by formaldehyde.
Autorzy:: Zhang Z; College of Public Health and Laboratory Medicine, Hunan University of Medicine, 492 Jinxi South Road, Huaihua, Hunan, 418000, People's Republic of China.
Yang Y; College of Public Health and Laboratory Medicine, Hunan University of Medicine, 492 Jinxi South Road, Huaihua, Hunan, 418000, People's Republic of China.
Hu C; College of Public Health and Laboratory Medicine, Hunan University of Medicine, 492 Jinxi South Road, Huaihua, Hunan, 418000, People's Republic of China. .
Zhang Z; Hunan Provincial Key Laboratory of Dong Medicine, Hunan University of Medicine, Huaihua, Hunan, 418000, People's Republic of China.; Показати більше
Źródło:: Scientific reports [Sci Rep] 2023 Oct 14; Vol. 13 (1), pp. 17465. Date of Electronic Publication: 2023 Oct 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Adducts*/pharmacology
DNA Damage*
Mice ; Animals ; Male ; 8-Hydroxy-2'-Deoxyguanosine ; Oxidative Stress ; Formaldehyde/toxicity ; Proteins/pharmacology ; Superoxide Dismutase/metabolism ; Deoxyguanosine
SCR Organism:: Kunming mice

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Стрибайте на позицію: 15.

Tytuł:: Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response.
Autorzy:: Alvi E; Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; Laboratory of Biochemical Cell Dynamics, Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Mochizuki AL; Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; CiRA Foundation, Kyoto, Japan.
Katsuki Y; Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; Department of Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Ogawa M; Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Qi F; Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Okamoto Y; Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
Takata M; Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; Multilayer Network Research Unit, Research Coordination Alliance, Kyoto University, Kyoto, Japan.
Mu A; Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan. .; Multilayer Network Research Unit, Research Coordination Alliance, Kyoto University, Kyoto, Japan. .; Показати більше
Źródło:: Communications biology [Commun Biol] 2023 Oct 13; Vol. 6 (1), pp. 1038. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Damage*
Nuclear Proteins*/metabolism
Humans ; Mice ; Animals

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Стрибайте на позицію: 16.

Tytuł:: Fuzzy interactions between the auto-phosphorylated C-terminus and the kinase domain of CK1δ inhibits activation of TAp63α.
Autorzy:: Lambert M; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt/Main, Germany.
Gebel J; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt/Main, Germany.
Trejtnar C; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt/Main, Germany.
Wesch N; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt/Main, Germany.
Bozkurt S; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt/Main, Germany.
Adrian-Allgood M; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt/Main, Germany.
Löhr F; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt/Main, Germany.
Münch C; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt/Main, Germany.; Frankfurt Cancer Institute, Frankfurt/Main, Germany.; Cardio-Pulmonary Institute, Frankfurt/Main, Germany.
Dötsch V; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt/Main, Germany. .; Показати більше
Źródło:: Scientific reports [Sci Rep] 2023 Sep 30; Vol. 13 (1), pp. 16423. Date of Electronic Publication: 2023 Sep 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Damage*
Apoptosis*
Phosphorylation ; Oocytes/metabolism ; DNA Breaks, Double-Stranded

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Стрибайте на позицію: 17.

Tytuł:: Impact of fractionated cisplatin and radiation treatment on cell growth and accumulation of DNA damage in two normal cell types differing in origin.
Autorzy:: Akuwudike P; Centre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius väg 20C, 106 91, Stockholm, Sweden.
López-Riego M; Centre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius väg 20C, 106 91, Stockholm, Sweden.
Dehours C; Centre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius väg 20C, 106 91, Stockholm, Sweden.; Polytech Angers l École d'Ingénieurs, Angers, France.
Lundholm L; Centre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius väg 20C, 106 91, Stockholm, Sweden.
Wojcik A; Centre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius väg 20C, 106 91, Stockholm, Sweden. .; Institute of Biology, Jan Kochanowski University, Kielce, Poland. .; Показати більше
Źródło:: Scientific reports [Sci Rep] 2023 Sep 09; Vol. 13 (1), pp. 14891. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cisplatin*/pharmacology
DNA Damage*
Humans ; Carcinogenesis ; Cell Cycle ; Cell Proliferation

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Стрибайте на позицію: 18.

Tytuł:: Integrative blood-based characterization of oxidative mitochondrial DNA damage variants implicates Mexican American's metabolic risk for developing Alzheimer's disease.
Autorzy:: Reid DM; Microbiology, Immunology, and Genetics, School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX, USA.
Barber RC; Family Medicine, Texas College of Osteopathic Medicine, UNT Health Science Center, Fort Worth, TX, USA.; Institue for Translational Research, UNT Health Science Center, Fort Worth, TX, USA.
Jones HP; Microbiology, Immunology, and Genetics, School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX, USA.
Thorpe RJ Jr; Microbiology, Immunology, and Genetics, School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX, USA.; Johns Hopkins Center for Health Disparities Solutions, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Sun J; Microbiology, Immunology, and Genetics, School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX, USA.
Zhou Z; Biostatistics and Epidemiology, School of Public Health, UNT Health Science Center, Fort Worth, TX, USA.
Phillips NR; Microbiology, Immunology, and Genetics, School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX, USA. .; Institue for Translational Research, UNT Health Science Center, Fort Worth, TX, USA. .; Показати більше
Źródło:: Scientific reports [Sci Rep] 2023 Sep 07; Vol. 13 (1), pp. 14765. Date of Electronic Publication: 2023 Sep 07.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Alzheimer Disease*/genetics
DNA, Mitochondrial*/genetics
Mitochondria*/genetics
Oxidative Stress*/genetics
DNA Damage*/genetics
Aged ; Humans ; Guanine ; Mexican Americans/genetics ; White/genetics

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Стрибайте на позицію: 19.

Tytuł:: Electroactive nanoinjection platform for intracellular delivery and gene silencing.
Autorzy:: Shokouhi AR; Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia.; Melbourne Centre for Nanofabrication, Victorian Node of the Australian National Fabrication Facility, 151 Wellington Road, Clayton, VIC, 3168, Australia.
Chen Y; Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia.; Melbourne Centre for Nanofabrication, Victorian Node of the Australian National Fabrication Facility, 151 Wellington Road, Clayton, VIC, 3168, Australia.
Yoh HZ; Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia.; Melbourne Centre for Nanofabrication, Victorian Node of the Australian National Fabrication Facility, 151 Wellington Road, Clayton, VIC, 3168, Australia.
Murayama T; Institute of Semiconductor and Electronics Technologies, ULVAC Inc, 1220-1 Suyama, Susono, Shizuoka, 410-1231, Japan.
Suu K; Institute of Semiconductor and Electronics Technologies, ULVAC Inc, 1220-1 Suyama, Susono, Shizuoka, 410-1231, Japan.
Morikawa Y; Institute of Semiconductor and Electronics Technologies, ULVAC Inc, 1220-1 Suyama, Susono, Shizuoka, 410-1231, Japan.
Brenker J; Department of Mechanical and Aerospace Engineering, Monash University, Wellington Rd, Clayton, VIC, 3168, Australia.
Alan T; Department of Mechanical and Aerospace Engineering, Monash University, Wellington Rd, Clayton, VIC, 3168, Australia.
Voelcker NH; Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia. .; Melbourne Centre for Nanofabrication, Victorian Node of the Australian National Fabrication Facility, 151 Wellington Road, Clayton, VIC, 3168, Australia. .; INM-Leibniz Institute for New Materials, Campus D2 2, 66123, Saarbrücken, Germany. .; Department of Materials Science and Engineering, Monash University, 22 Alliance Lane, Clayton, VIC, 3168, Australia. .
Elnathan R; Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia. .; Melbourne Centre for Nanofabrication, Victorian Node of the Australian National Fabrication Facility, 151 Wellington Road, Clayton, VIC, 3168, Australia. .; Faculty of Health, School of Medicine, Deakin University, Waurn Ponds, Melbourne, VIC, 3216, Australia. .; Institute for Frontier Materials, Deakin University, Geelong Waurn Ponds campus, Melbourne, VIC, 3216, Australia. .; The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Deakin University, Geelong Waurn Ponds Campus, Melbourne, VIC, 3216, Australia. .; Показати більше
Źródło:: Journal of nanobiotechnology [J Nanobiotechnology] 2023 Aug 17; Vol. 21 (1), pp. 273. Date of Electronic Publication: 2023 Aug 17.
Typ publikacji:: Journal Article
MeSH Terms:: Antibodies*
DNA Damage*
Animals ; Mice ; Cell Membrane ; Cell Survival ; Gene Silencing

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Стрибайте на позицію: 20.

Tytuł:: Novel Cellular Functions of ATR for Therapeutic Targeting: Embryogenesis to Tumorigenesis.
Autorzy:: Biswas H; Department of Cell and Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.
Makinwa Y; Department of Cell and Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.
Zou Y; Department of Cell and Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.; Показати більше
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 20; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:: Journal Article; Review
MeSH Terms:: DNA Damage*
Neoplasms*/drug therapy
Neoplasms*/genetics
Humans ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Carcinogenesis/genetics ; Cell Transformation, Neoplastic ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Signal Transduction ; Embryonic Development

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